6 Things You Should Know About Inositol For Polycystic Ovarian Syndrome


Women with polycystic ovary syndrome or PCOS have hormonal imbalances. This can lead to a number of health problems, such as diabetes and infertility. Treatment with a vitamin-like substance called inositol has shown promising results.

Read on to learn more about inositol supplements and how they can help women with PCOS control blood sugar and get pregnant.

Get Medical Information / Laura Porter

Inositols and SOP

Inositol is a type of sugar made by the body. They help balance chemicals that control mood swings, blood sugar levels, fertility and metabolism, and the process of converting food into energy.

Many women with PCOS are insulin resistant . Their bodies make insulin but cannot use it efficiently. This increases the risk of diabetes, infertility, obesity, and high cholesterol levels.

Inositols make molecules participate in the body's response to insulin. The researchers say that inositols can be used as a backup messaging system when the normal insulin signaling system fails.

You can get inositol by eating healthy foods like:

Fruits : melon, grapefruit, other citrus.

Beans: Lima, dark blue

Cereals: brown rice, whole grains

Nuts: almonds, walnuts

You can also buy inositol supplements, tablets, or powders mixed with water. Inositol is well tolerated by most people. This is important because doctors often use diabetes medications to treat PCOS. Metformin is associated with serious side effects such as diarrhea, stomach pain, and nausea.

There are nine inositols in all. Two that seem to benefit women with PCOS are myo- (MI) and d-chiro (DCI). Both are important for the body's response to insulin. MI also helps control the hormones necessary for the production of eggs in the ovaries. DCI also helps control male hormone levels in women.

99% of the inositols in the body are myocardial infarction, but a certain level of ICD is required to maintain a healthy balance. Researchers believe that many women with PCOS are less able to convert MI to ICD. Lower levels of DCI in body tissues increase the risk of insulin resistance and high blood sugar levels.

The ratio reduces blood sugar, cholesterol and improves fertility.

In the past, researchers have tried to show that IM or ICD is better for treating PCOS. Several recent studies have shown that using a combination of IM and ICD can help improve insulin sensitivity and resume ovulation . This is part of a woman's monthly cycle when the ovary releases an egg.

Researchers know that in healthy women, the ratio of IM to BCI in most body tissues is about 40: 1. Many women with PCOS have a much higher ratio.

Studies using 40: 1 MI to ICD ratio treatments have shown it to be more beneficial in improving fertility rates in women with PCOS. However, supplement companies sell drugs with varying proportions of inositol. A recent observational study found that the ratio of MI to INN in PCOS products can range from 0.04 to 1 to 104 to 1.

Some medications only contain INN. Others add vitamins, artificial sugar, and other substances. There is no evidence that these ingredients help. In fact, some artificial sugars like sucralose (Splenda) and sugar alcohols like sorbitol (found in sugar-free candy and chewing gum) can make the treatment less effective. This is because they interfere with the absorption of the myocardial infarction by the small intestine.

A 40-to-one ratio has also been shown to reduce insulin and cholesterol levels and inflammation in women with PCOS better than treatment with MI alone.

Another study found that compared to the prescription diabetes drug metformin, women who took a 40: 1 IM to ICD ratio had significantly better rates of weight loss, ovulation, and pregnancy (46.7% vs. 11, 2%).

The relationship improves menstruation, ovulation, and egg quality.

PCOS is the most common cause of infertility, affecting up to 12% of women. Symptoms usually start in the first period. The levels of MI and DCI in tissues differ from levels in some organs. In women with PCOS, there is an imbalance in the ratio of MI and BCI in the ovaries. This can affect them:

Periods : Women with PCOS may have irregular periods or no periods. Inositol treatment has been shown to help improve insulin sensitivity and reduce levels of male hormones, such as testosterone, in women with PCOS. Helps restore menstruation.

Ovulation: Women with PCOS may not ovulate every month or may not ovulate at all. Researchers attribute this to too low a MI and too high an ICD in the ovaries.

Egg quality : Women with PCOS have been shown to produce less mature eggs than women without the disease (13.8% to 5.8%, respectively). Researchers attribute this to very little MI in the follicular fluid that surrounds the eggs in the ovaries.

A high rate of myocardial infarction in follicular fluid is required for the maturation of healthy eggs. In healthy women, the ratio of IM to ICD in this fluid is approximately 100: 1. However, in infertile women with PCOS, the mean ratio of IM to ICD in this fluid is 0.2: 1.

Inositol treatment can help restore ovulation and improve egg quality. However, the researchers caution that using the correct formula is essential. High doses of INN have been shown to adversely affect ovarian cells, which can develop into eggs. Too high a dose of DCI can also prevent the body from absorbing MI.

MI is used to treat gestational diabetes

Women with PCOS are four times more likely to develop diabetes than women without it. They are also at increased risk for gestational diabetes (HD), which occurs during pregnancy. One study found that the risk was almost 20% higher.

Researchers have shown that taking IM supplements can lower blood sugar and GD risk in overweight women with PCOS.

A study in gynecology and endocrinology found that the incidence of HD among pregnant women with PCOS who received MI was 17.4% compared to 54% among those who did not.


Inositol is a sugar produced by the body that helps regulate insulin and cholesterol levels. They also play a key role in detecting mood swings and helping you get pregnant. Two types of inositol are useful for treating women with PCOS, MI and ICD.

You can get inositol from certain foods or supplements. Research shows that if you are battling infertility, a 40: 1 ratio of MI to DCI is more beneficial. This ratio also helps lower insulin and cholesterol levels in women with PCOS.

Get the word of drug information

Research on the use of inositol supplement combinations to treat women with PCOS is very promising. It is also interesting because it is inexpensive compared to other fertility treatments. If you have PCOS, you can ask your doctor if it might benefit you.

You may be tempted to try taking inositol supplements on your own. Bad idea. For example, taking too much INN can lower estrogen levels and increase male hormone levels. Estrogen provides several benefits, such as protecting bones and preventing breast cancer. Increasing testosterone levels in women who are already at risk for infertility is also not practical.

If your healthcare provider agrees and decides to try inositol, you may need to be very careful about what you eat and drink. Some artificial sugars and sugar alcohols reduce the effects of these additives.

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