Acne treatment with 5% Aczone gel (dapsone)


Aczone is a prescription-only brand of dapsone for acne. It is used to treat mild to moderate acne vulgaris . It comes in the form of a gel that is applied directly to the skin.

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You can use Aczone (dapsone) to treat acne on both the face and the body. It's especially good for inflammatory acne breakouts, but it's also somewhat effective for treating non-inflammatory breakouts like acne and milia .


Dapsone is an antimicrobial agent, so it reduces Propionibacteria acnes (bacteria that cause acne breakouts). Thus, it works in the same way as topical antibiotics such as erythromycin or clindamycin . In fact, Aczone is technically an antibiotic because the active ingredient in the drug, dapsone, is a sulfone antibiotic.

Aczone also reduces inflammation. So it can help soothe those big red pimples.

Aczone can be used alone or in conjunction with other topical or oral acne medications . This will help clear acne faster and get better results. Your doctor or dermatologist will tell you if this treatment plan is right for you.

However, keep in mind that if you use Aczone with benzoyl peroxide , your skin may temporarily turn yellow, orange, or brown. Don't worry, this color is generally washable. But you won't want to go for a walk until you realize that your acne medications have made your skin look unusual in color.

To prevent this problem, make sure each drug is fully absorbed before using the other. Or better yet, use Benzoyl Peroxide in the morning and Aczone in the evening, or vice versa.


Aczone can be used to treat acne in both adults and adolescents over 12 years of age. Interestingly, in clinical trials, women saw more improvement than men when using this treatment. but for boys it is still an effective option.

When it comes to acne medications, it's pretty mild. If topical retinoids (such as retin-A or diferin ) are too much for your skin, making it very dry, red, and flaky, Aczone may be a good alternative. It is generally not as harmful to the skin as topical retinoids.

There are currently no good studies demonstrating the use and safety of Aczone during pregnancy. Therefore, it is not clear how this could affect the developing fetus. Tell your doctor or dermatologist if you are pregnant.

There are acne medications that are best used during pregnancy . Also, do not use Aczone if you are breastfeeding.


Typically, you apply a pea-sized amount to acne-affected areas twice a day. Rub gently but completely. It is absorbed quite quickly.

Aczone can be used on the face and neck, as well as the chest, back, arms, or wherever there is an acne problem. The trick is to apply it to the entire area where acne is a problem, not just the individual pimples.

Also, make sure your skin is clean and well dry before applying.

Keep using this medicine even if you don't see improvement or if new acne is still forming. It may take up to a full 12 weeks before you see any real improvement.

And like most acne medications, Aczone is not for everyone. If you use it for 12 weeks without noticing much improvement, tell your doctor or dermatologist. You will most likely be prescribed additional or different acne treatments.

Side effects

Aczone can cause dryness, peeling, and redness of the skin. For some people, it can also make the skin look oily.

Tell your doctor if you are deficient in glucose-6-phosphate dehydrogenase (G6PD). Oral dapsone can cause hemolytic anemia. A topical medication is unlikely to have the same effect because your skin cannot absorb enough. However, just in case, tell your doctor or dermatologist if you have a G6PD deficiency.

Get the word of drug information

Your doctor or dermatologist will tell you if Aczone is suitable for treating your acne. If not, remember that you have many other acne treatment options .

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