Full text biomedical articles

Leflunomide increased the renal exposure of acyclovir by inhibiting OAT1/3 and MRP2

Xiao-ying Liao, Qiang-qiang Deng, Li Han, Zhi-tao Wu, Zhao-liang Peng, Yuan Xie, Guang-ji Wang, Ji-ye Aa, Guo-yu Pan
Acta Pharmacol Sin. 2020 Jan; 41(1): 129–137. Published online 2019 Jul 24. doi: 10.1038/s41401-019-0283-z


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Effectiveness of acyclovir in the treatment of pityriasis rosea. A systematic review and meta-analysis

Milton Rodriguez-Zuniga, Natalie Torres, Herney Garcia-Perdomo
An Bras Dermatol. 2018 Sep-Oct; 93(5): 686–695. doi: 10.1590/abd1806-4841.20187252


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Acute Kidney Injury During Treatment with Intravenous Acyclovir for Suspected or Confirmed Neonatal Herpes Simplex Virus Infection

Kevin J. Downes, Craig L. K. Boge, Elande Baro, Gerold T. Wharton, Kellie M. Liston, Brittany L. Haltzman, Hannah M. Emerson, Edwin Doe, Rosanna Fulchiero, Van Tran, Lilly Yen, Phuong Lieu, Sara L. Van Driest, Alison G. Grisso, Ida T. Aka, Jennifer Hale, Jessica Gillon, Julie S. Pingel, Susan E. Coffin, Ann W. McMahon
J Pediatr. Author manuscript; available in PMC 2021 Apr 1.
Published in final edited form as: J Pediatr. 2020 Apr; 219: 126–132.e2. Published online 2020 Feb 6. doi: 10.1016/j.jpeds.2019.12.056


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Physiologically Based Pharmacokinetic Models to Predict Maternal Pharmacokinetics and Fetal Exposure to Emtricitabine and Acyclovir

Xiaomei I. Liu, Jeremiah D. Momper, Natella Rakhmanina, John N. van den Anker, Dionna J. Green, Gilbert J. Burckart, Brookie M. Best, Mark Mirochnick, Edmund V. Capparelli, André Dallmann
J Clin Pharmacol. Author manuscript; available in PMC 2021 Feb 1.
Published in final edited form as: J Clin Pharmacol. 2020 Feb; 60(2): 240–255. Published online 2019 Sep 6. doi: 10.1002/jcph.1515


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Development of a gastroretentive delivery system for acyclovir by 3D printing technology and its in vivo pharmacokinetic evaluation in Beagle dogs

Soyoung Shin, Tae Hwan Kim, Seok Won Jeong, Seung Eun Chung, Da Young Lee, Do-Hyung Kim, Beom Soo Shin
PLoS One. 2019; 14(5): e0216875. Published online 2019 May 15. doi: 10.1371/journal.pone.0216875


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Acyclovir Has Low but Detectable Influence on HLA-B*57:01 Specificity without Inducing Hypersensitivity

Imir G. Metushi, Amanda Wriston, Priyanka Banerjee, Bjoern Oliver Gohlke, A. Michelle English, Andrew Lucas, Carrie Moore, John Sidney, Soren Buus, David A. Ostrov, Simon Mallal, Elizabeth Phillips, Jeffrey Shabanowitz, Donald F. Hunt, Robert Preissner, Bjoern Peters
PLoS One. 2015; 10(5): e0124878. Published online 2015 May 29. doi: 10.1371/journal.pone.0124878


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Niosomes: A Strategy toward Prevention of Clinically Significant Drug Incompatibilities

Hebatallah B. Mohamed, Sohair M. El-Shanawany, Mostafa A. Hamad, Mahmoud Elsabahy
Sci Rep. 2017; 7: 6340. Published online 2017 Jul 24. doi: 10.1038/s41598-017-06955-w


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Delay of Alternative Antiviral Therapy and Poor Outcomes of Acyclovir-Resistant Herpes Simplex Virus Infections in Recipients of Allogeneic Stem Cell Transplant

Ella J. Ariza-Heredia, Roy F. Chemaly, Lokesh R. Shahani, Ying Jang, Richard Champlin, Victor E. Mulanovich
Transpl Int. Author manuscript; available in PMC 2019 Jun 1.
Published in final edited form as: Transpl Int. 2018 Jun; 31(6): 639–648. Published online 2018 Mar 13. doi: 10.1111/tri.13142


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Immunomodulatory Strategies in Herpes Simplex Virus Encephalitis

Jocelyne Piret, Guy Boivin
Clin Microbiol Rev. 2020 Apr; 33(2): e00105-19. Published online 2020 Feb 12. doi: 10.1128/CMR.00105-19


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Effect of suppressive acyclovir administered to HSV-2 positive mothers from week 28 to 36 weeks of pregnancy on adverse obstetric outcomes: a double-blind randomised placebo-controlled trial

Sarah Nakubulwa, Dan K. Kaye, Freddie Bwanga, Nazarius Mbona Tumwesigye, Edith Nakku-Joloba, Florence Mirembe
Reprod Health. 2017; 14: 31. Published online 2017 Mar 3. doi: 10.1186/s12978-017-0292-7


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Impact of a Rapid Herpes Simplex Virus PCR Assay on Duration of Acyclovir Therapy

Tam T. Van, Kanokporn Mongkolrattanothai, Melissa Arevalo, Maryann Lustestica, Jennifer Dien Bard
J Clin Microbiol. 2017 May; 55(5): 1557–1565. Prepublished online 2017 Mar 8. Published online 2017 Apr 25. doi: 10.1128/JCM.02559-16


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In Silico Absorption Analysis of Valacyclovir in Wildtype and Pept1 Knockout Mice Following Oral Dose Escalation

Bei Yang, David E. Smith, B. Yang, D. E. Smith
Pharm Res. Author manuscript; available in PMC 2018 Nov 1.
Published in final edited form as: Pharm Res. 2017 Nov; 34(11): 2349–2361. Published online 2017 Aug 2. doi: 10.1007/s11095-017-2242-z


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Tricyclic Derivative of Acyclovir and Its Esters in Relation to the Esters of Acyclovir Enzymatic Stability: Enzymatic Stability Study

Izabela Muszalska-Kolos, Monika A. Lesniewska-Kowiel, Szymon Plewa, Agnieszka Klupczyńska
Molecules. 2020 May; 25(9): 2156. Published online 2020 May 5. doi: 10.3390/molecules25092156


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Valacyclovir versus acyclovir for the treatment of herpes zoster ophthalmicus in immunocompetent patients

Alexander K Schuster, Björn C Harder, Frank C Schlichtenbrede, Marc N Jarczok, Jonas Tesarz
Cochrane Database Syst Rev. 2016 Nov; 2016(11): CD011503. Published online 2016 Nov 14. doi: 10.1002/14651858.CD011503.pub2


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Acyclovir for Mechanically Ventilated Patients With Herpes Simplex Virus Oropharyngeal Reactivation: A Randomized Clinical Trial

Charles-Edouard Luyt, Jean-Marie Forel, David Hajage, Samir Jaber, Sophie Cayot-Constantin, Thomas Rimmelé, Elisabeth Coupez, Qin Lu, Mamadou Hassimiou Diallo, Christine Penot-Ragon, Marc Clavel, Carole Schwebel, Jean-François Timsit, Jean-Pierre Bedos, Caroline Hauw-Berlemont, Jérémy Bourenne, Julien Mayaux, Jean-Yves Lefrant, Jean-Paul Mira, Alain Combes, Michel Wolff, Jean Chastre, Laurent Papazian
JAMA Intern Med. 2020 Feb; 180(2): 263–272. Published online 2019 Dec 16. doi: 10.1001/jamainternmed.2019.5713


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PEGylated Lipid Polymeric Nanoparticle–Encapsulated Acyclovir for In Vitro Controlled Release and Ex Vivo Gut Sac Permeation

Syed Mahmood, Kong Chak Kiong, Chun Shern Tham, Tan Choo Chien, Ayah Rebhi Hilles, Jayarama Reddy Venugopal
AAPS PharmSciTech. 2020 Oct; 21(7): 285. Published online 2020 Oct 14. doi: 10.1208/s12249-020-01810-0


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Comparison of antibiotic and acyclovir usage before and after the implementation of an on-site FilmArray meningitis/encephalitis panel in an academic tertiary pediatric hospital: a retrospective observational study

Alexandra Hagen, Anna Eichinger, Melanie Meyer-Buehn, Tilmann Schober, Johannes Huebner
BMC Pediatr. 2020; 20: 56. Published online 2020 Feb 5. doi: 10.1186/s12887-020-1944-2


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Safety of High-Dose Acyclovir in Infants with Suspected and Confirmed Neonatal Herpes Simplex Virus Infections

Jessica E. Ericson, Martyn Gostelow, Julie Autmizguine, Christoph P. Hornik, Reese H. Clark, Daniel K. Benjamin, Jr., P. Brian Smith
Pediatr Infect Dis J. Author manuscript; available in PMC 2018 Apr 1.
Published in final edited form as: Pediatr Infect Dis J. 2017 Apr; 36(4): 369–373. doi: 10.1097/INF.0000000000001451


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Prospective, Controlled Study of Acyclovir Pharmacokinetics in Obese Patients

R. Brigg Turner, Aaron Cumpston, Michael Sweet, Frank Briggs, Douglas Slain, Sijin Wen, Michael Craig, Mehdi Hamadani, William Petros
Antimicrob Agents Chemother. 2016 Mar; 60(3): 1830–1833. Prepublished online 2016 Jan 11. Published online 2016 Feb 26. doi: 10.1128/AAC.02010-15


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Role of Intravenous Acyclovir in Treatment of Herpes Simplex Virus Stromal Keratitis with Ulceration: A Review of 2 Cases

Punyanuch Pisitpayat, Passara Jongkhajornpong, Kaevalin Lekhanont, Manachai Nonpassopon
Am J Case Rep. 2021; 22: e930467-1–e930467-6. Published online 2021 Jun 16. doi: 10.12659/AJCR.930467


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