Advil (ibuprofen) use, dosage, and side effects

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Advil, an over-the-counter drug, is a brand-name version of ibuprofen , a non-steroidal anti -inflammatory drug (NSAID) used to treat mild pain. Each Advil tablet for adults contains 200 milligrams (mg) of ibuprofen. Ibuprofen is also available in generic form and is the main ingredient in another brand of Motrin.

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Indications

Advil is used for a number of common ailments. You can use it to relieve pain, reduce inflammation, and lower your body temperature if you have a fever.

The rate of occurrence of pain relief depends on the drug Advil. Its effect usually lasts four to eight hours, but you must follow the specific instructions on the label.

Advil can be used to relieve minor aches and pains associated with :

  • Cold
  • Headache
  • Menstrual cramps
  • Toothache
  • Back pain and muscles
  • Mild arthritis pain

Please note that Advil is used to temporarily relieve symptoms, which means that it does not cure any disease or health condition.

Dose

When taking Advil, you should use the lowest effective dose to minimize the possibility of side effects. Your healthcare professional will help you determine the correct dose.

Adults and children 12 years of age and older can take up to two Advil tablets every four to six hours. You should not take more than six tablets in 24 hours or take Advil for more than 10 days unless directed by your healthcare professional.

Advil for adults is available as 200 mg film-coated tablets, quick-release film-coated tablets, and 200 mg liquid gels. Advil Liqui-gels is a fast-acting formulation containing solubilized ibuprofen dissolved in the liquid center of a softgel capsule.

While Advil Regular Strength is recommended for adults, there are pediatric forms that include Advil Junior Strength chewable tablets, Advil infant drops, and Advil suspension for children. For children, the recommended dose of Advil depends on their weight, but age can sometimes be used as a guide. Each package comes with special measuring cups or spoons and instructions for measuring the dose for your child.

How does it work

Advil works through several biochemical mechanisms, some of which are associated with the inhibition of cyclooxygenase (COX) , an enzyme that helps in the production of prostaglandins and thromboxane. Prostaglandins are involved in relieving pain and fever, thromboxane is involved in blood clots, and COX also helps maintain a protective layer on the stomach lining.

The therapeutic effects of Advil to reduce pain and lower fever are based on a decrease in the action of prostaglandins. Advil's side effects on the gastrointestinal tract are also associated with its inhibition of COX and thromboxane.

Side effects, risks and contraindications.

Advil can cause side effects, but it is important to know that Advil's side effects, risks , and contraindications are the same as with other brands of ibuprofen and are very similar to the side effects of other NSAIDs.

Side effects

Advil and other NSAIDs can cause an upset stomach. You can reduce your chances of developing an upset stomach if you take it with food or milk. Advil can also cause bleeding, mainly stomach bleeding. It is important to know the symptoms of stomach bleeding, which include dark stools, fatigue, dizziness, and blood in vomit.

Advil can also cause easy bruising, prolonged bleeding from a cut, blood in the urine, and bleeding from the eye.

Advil rarely causes allergies, leading to symptoms such as hives, facial swelling, asthma, rashes, blisters, or shock.

Advil can increase the chance of developing kidney damage. This risk increases in patients with dehydration or hypovolemia. If you have underlying kidney disease such as diabetes, high blood pressure, or any other reason, refrain from taking Advil or other NSAIDs as much as possible. If you must take it, make sure you are sufficiently hydrated.

Advil can also lower blood sodium levels and raise blood potassium levels. If you are taking blood pressure medications that raise blood potassium levels or lower blood sodium levels, refrain from taking Advil or other NSAIDs. Advil can also cause volume overload, so if you are taking medications to remove excess water in your body, you should not take Advil.

Risks

Advil can increase your risk of heart attack or stroke . The risk increases with higher doses or with long-term use of Advil. Aspirin, another NSAID, does not increase this risk; in fact, it is often used to reduce the risk of strokes and heart attacks .

Contraindications

You should not take Advil immediately before or after heart bypass surgery. Also, unless otherwise stated, pregnant women should not take Advil during the last trimester.

Several factors increase the risk of bleeding while taking Advil. Do not use if you have any of the following contraindications, unless directed by your healthcare professional:

  • Age over 60 years
  • Taking a blood thinner
  • Using another NSAID
  • Ulcer history
  • Alcohol consumption

Get the word of drug information

Advil is one of the most widely used over-the-counter medications. It is usually very safe, but there are risks. Make sure to follow the instructions and do not exceed the recommended dosage. If you have persistent pain or fever, or symptoms that do not improve with Advil, be sure to see your doctor, as your symptoms may be a sign of an underlying condition that requires medical evaluation.

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