Clinical Trials

Reduced Clavulanate Formulation of Amoxicillin-Clavulanate in Children 6-23 Months With Acute Otitis Media

Condition:   Acute Otitis Media
Intervention:   Drug: Amoxicillin-Clavulanate potassium
Sponsor:   Nader Shaikh
Completed
Tue, 15 Dec 2015 12:00:00 EST

Bioequivalence Study of Clavamox, Film-coated Tablets, 875 mg + 125 mg Pharmtechnology LLC, Belarus), and Augmentin®, Film-coated Tablets, 875 mg + 125 mg (GlaxoSmithKline Trading CJSC, Russia), in Healthy Volunteers Under Fasting Conditions

Condition:   Bioequivalence
Interventions:   Drug: Clavamox;   Drug: Augmentin®
Sponsors:   Pharmtechnology LLC;   ClinPharmInvest, LLC
Completed
Thu, 11 Oct 2018 12:00:00 EDT

Bioequivalence Study of Clavamox, Powder for Oral Suspension, 400 mg + 57 mg / 5 ml (Pharmtechnology LLC, Belarus), and Augmentin®, Powder for Oral Suspension, 400 mg + 57 mg / 5 ml (GlaxoSmithKline Trading CJSC, Russia), in Healthy Volunteers Under Fasting Conditions

Condition:   Bioequivalence
Interventions:   Drug: Clavamox;   Drug: Augmentin®
Sponsors:   Pharmtechnology LLC;   ClinPharmInvest, LLC
Completed
Mon, 06 Aug 2018 12:00:00 EDT

Study to Evaluate the Safety and Clinical Efficacy of Augmentin® Extra Strength-600 in Children With Acute Otitis Media in India

Condition:   Otitis Media
Intervention:   Drug: Augmentin (ES)-600
Sponsors:   GlaxoSmithKline;   Iqvia Pty Ltd
Not yet recruiting
Fri, 23 Oct 2020 12:00:00 EDT

Clindamycin Versus Amoxicillin With Clavulanic Acid in Prevention of Early Dental Implants Failure

Condition:   Antibiotics Causing Adverse Effects in Therapeutic Use
Interventions:   Drug: Clindamycin 300 mg;   Drug: Amoxicillin with Clavulanic Acid 635mg
Sponsor:   Jordan University Hospital
Not yet recruiting
Wed, 28 Jul 2021 12:00:00 EDT

Amoxicillin-clavulanate in Treating Acute Otitis Media Evaluated by Daily Tympanometry

Condition:   Otitis Media, Suppurative
Interventions:   Drug: Amoxicillin-clavulanate;   Drug: Placebo
Sponsor:   University of Oulu
Completed
Fri, 19 Nov 2010 12:00:00 EST

Comparison of Intravenous Co-amoxiclav Versus Benzyl Penicillin

Condition:   Tonsillitis Streptococcal
Intervention:   Drug: inj co-amoxiclav 50 units/kg/day vs inj Benzyl Penicillin 25000 units/kg/day
Sponsor:   Combined Military Hospital, Pakistan
Completed
Thu, 02 Jan 2020 12:00:00 EST

Efficacy of Short-Course Antimicrobial Treatment for Children With Acute Otitis Media and Impact on Resistance

Condition:   Acute Otitis Media
Interventions:   Drug: Amoxicillin-Clavulanate, 10 days;   Drug: Amoxicillin-Clavulanate, 5 days
Sponsors:   Alejandro Hoberman;   National Institute of Allergy and Infectious Diseases (NIAID)
Terminated
Wed, 18 Jan 2012 12:00:00 EST

Amoxicillin-Clavulanic Acid 400 mg-57 mg Chewable Tablets Under Fasting Conditions

Condition:   Healthy
Interventions:   Drug: amoxicillin-clavulanic acid;   Drug: Augmentin®
Sponsor:   Teva Pharmaceuticals USA
Completed
Wed, 04 Feb 2009 12:00:00 EST

Amoxicillin-Clavulanic Acid 400 mg-57 mg Chewable Tablets Under Non-Fasting Conditions

Condition:   Healthy
Interventions:   Drug: amoxicillin-clavulanic acid;   Drug: Augmentin®
Sponsor:   Teva Pharmaceuticals USA
Completed
Wed, 04 Feb 2009 12:00:00 EST

Higher Versus Standard Dose of Amoxicillin-clavulanate in Pediatric PBB

Condition:   Protracted Bacterial Bronchitis
Intervention:   Drug: Amoxicillin-Clavulanate 200 Mg-28.5 Mg Oral dry suspension
Sponsor:   Second Affiliated Hospital of Wenzhou Medical University
Not yet recruiting
Thu, 07 May 2020 12:00:00 EDT

Bioequivalence Study of Amoxicillin-Clavulanic Acid 600 mg-42.9 mg/ 5 mL Oral Suspension Under Fed Conditions

Condition:   Healthy
Intervention:   Drug: amoxicillin-clavulanic acid 600 mg- 42.9 mg/ 5 mL oral suspension
Sponsor:   Ranbaxy Laboratories Limited
Completed
Thu, 23 Oct 2008 12:00:00 EDT

Bioequivalence Study of Amoxicillin-Clavulanic Acid 600 mg - 42.9 mg/ 5 mL Oral Suspension Under Fasting Conditions

Condition:   Healthy
Intervention:   Drug: Amoxicillin-Clavulanic acid 600mg - 42.9 mg/ 5 mL oral suspension
Sponsor:   Ranbaxy Laboratories Limited
Completed
Thu, 23 Oct 2008 12:00:00 EDT

Prophylaxis Of Wound Infections- Antibiotics in Renal Donation

Condition:   Infection
Interventions:   Drug: Co-Amoxiclav;   Drug: Normal Saline
Sponsor:   Guy's and St Thomas' NHS Foundation Trust
Completed
Tue, 18 Mar 2014 12:00:00 EDT

A Multicentre, Randomized as a Double Blind Study, Triple Placebo, Comparative of the Efficacy and Safety of an Association Secnidazol-Ciprofloxacin Compared With Amoxicillin-Clavulanic Acid for the Treatment of Uncomplicated Episode of Diverticular Sigmoïditis Among Adults

Condition:   Diverticular Sigmoïditis
Interventions:   Drug: Secnidazole, ciprofloxacine;   Drug: Amoxicillin-Clavulanic Acid
Sponsors:   Quanta Medical;   Laboratoires Iprad-Vegebom
Terminated
Tue, 27 Nov 2012 12:00:00 EST

Does Antibiotics Use During Surgery Help to Decrease Wound Infection and Increase Success After Ear Surgery in Children

Conditions:   Post Operative Wound Infection;   Graft Uptake;   Myringoplasty
Intervention:   Drug: Co-amoxiclav
Sponsor:   Tribhuvan University, Nepal
Completed
Tue, 09 Oct 2018 12:00:00 EDT

Routine Antibiotic vs. Directed Antibiotic Treatment in Snake Bite

Condition:   Snake Bites
Interventions:   Drug: Co-amoxiclav;   Biological: Tetanus toxoid
Sponsor:   Jawaharlal Institute of Postgraduate Medical Education & Research
Recruiting
Wed, 07 Oct 2015 12:00:00 EDT

Acute Otitis Media (AOM) Therapy Trial in Young Children

Condition:   Acute Otitis Media
Interventions:   Drug: amoxicillin-clavulanate;   Drug: Placebo
Sponsors:   University of Pittsburgh;   National Institute of Allergy and Infectious Diseases (NIAID)
Completed
Mon, 18 Sep 2006 12:00:00 EDT

Amoxicillin-clavulanate Alone or in Combination With Ciprofloxacin in Low-Risk Febrile Neutropenic Adult Patients: A Prospective, Double-blind, Randomized, Non-Inferiority Multicenter, Phase III Clinical Trial.

Condition:   Febrile Neutropenia
Interventions:   Drug: Placebo;   Drug: Amoxicillin Clavulanate;   Drug: Ciprofloxacin
Sponsor:   Poitiers University Hospital
Not yet recruiting
Wed, 06 Jan 2021 12:00:00 EST

Prophylactic Antibiotics in Comatose Survivors of Out-of-hospital Cardiac Arrest

Condition:   Out-of-hospital Cardiac Arrest
Intervention:   Drug: Amoxicillin-Clavulanic acid
Sponsor:   University Medical Centre Ljubljana
Completed
Wed, 14 Sep 2016 12:00:00 EDT

Effect of Tebipenem on Normal Human Intestinal Microbiota

Condition:   Healthy Volunteers
Interventions:   Drug: TBPM-PI-HBr;   Drug: amoxicillin-clavulanate
Sponsors:   Spero Therapeutics;   Iqvia Pty Ltd
Completed
Wed, 06 May 2020 12:00:00 EDT

A Clinical Study to Explore Biomarkers for Drug-induced Liver Injury (DILI)

Condition:   Healthy
Intervention:   Drug: Augmentin tablet
Sponsor:   Seoul National University Hospital
Completed
Wed, 21 May 2014 12:00:00 EDT

Antibiotic-Associated Diarrhea and the Role of Microorganisms in the Gut

Condition:   Antibiotic-associated Diarrhea
Intervention:   Drug: Amoxicillin-Clavulanate 875 Mg-125 Mg Oral Tablet
Sponsor:   Singapore General Hospital
Recruiting
Thu, 07 Nov 2019 12:00:00 EST

Efficacy of Amoxicilline/Clavulanic Acid in Patients Affected by Tic Disorder Colonized by Group A Streptococcus

Condition:   Tic Disorders
Interventions:   Drug: Amoxicillin-Potassium Clavulanate Combination;   Drug: placebo
Sponsor:   University of Roma La Sapienza
Unknown status
Wed, 22 May 2013 12:00:00 EDT

Diverticulitis: Antibiotics or Close Observation?

Condition:   Diverticulitis
Intervention:   Drug: Amoxicillin-clavulanate
Sponsors:   Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA);   ZonMw: The Netherlands Organisation for Health Research and Development;   Dutch Digestive Diseases Foundation
Unknown status
Tue, 27 Apr 2010 12:00:00 EDT

Hospitalised Pneumonia With Extended Treatment (HOPE) Study

Condition:   Pneumonia
Interventions:   Drug: Amoxicillin-clavulanic Acid;   Drug: Placebo (for Amoxicillin-clavulanic Acid)
Sponsors:   Menzies School of Health Research;   Griffith University;   Sarawak General Hospital;   University of Malaya;   The University of Queensland;   Queensland University of Technology;   Nanyang Technological University
Active, not recruiting
Thu, 26 May 2016 12:00:00 EDT

Efficacy of Antibiotics in Children With Acute Sinusitis: Which Subgroups Benefit?

Conditions:   Sinusitis;   Respiratory Tract Infections
Interventions:   Drug: Amoxicillin-clavulanate;   Drug: Placebo
Sponsors:   Nader Shaikh;   National Institute of Allergy and Infectious Diseases (NIAID)
Recruiting
Fri, 18 Sep 2015 12:00:00 EDT

Initial Non-operative Treatment Strategy Versus Appendectomy Treatment Strategy for Simple Appendicitis in Children

Condition:   Appendicitis
Interventions:   Drug: Augmentin + Gentamicin;   Procedure: Appendectomy
Sponsors:   Ramon Gorter;   ZonMw: The Netherlands Organisation for Health Research and Development;   VU University Medical Center
Recruiting
Fri, 29 Jul 2016 12:00:00 EDT

Antibiotic Prophylaxis for PEG in Children

Condition:   Infection
Interventions:   Drug: co-amoxiclav;   Dietary Supplement: Placebo
Sponsor:   Azienda Policlinico Umberto I
Unknown status
Wed, 05 Jun 2013 12:00:00 EDT

Place of Antibiotics in the Postoperative Acute Lithiasic Cholecystitis

Conditions:   Acute Lithiasic Cholecystitis Grade I or II;   Symptoms Lasting for Less Than 5 Days;   Required Cholecystectomy;   Preoperative Amoxicillin Clavulanic Acid for at Most 5 Days
Interventions:   Drug: Amoxicillin clavulanic acid;   Other: No medication
Sponsor:   Centre Hospitalier Universitaire, Amiens
Completed
Wed, 18 Nov 2009 12:00:00 EST

2-day Prophylactic Antibiotic is Effective in Transoral Endoscopic Thyroidectomy

Condition:   Thyroid Nodule
Intervention:   Drug: Amoxicillin Clavulanate
Sponsor:   Chang Gung Memorial Hospital
Not yet recruiting
Thu, 13 Feb 2020 12:00:00 EST

Assessing the Necessity of Prescribing Antibiotics (Clavulin or Clindamycin Versus Placebo) Post-peritonsillar Abscess Drainage

Condition:   Peritonsillar Abscess
Interventions:   Drug: Clavulin;   Drug: Randomization to Placebo;   Drug: Clindamycin
Sponsor:   Lawson Health Research Institute
Withdrawn
Mon, 29 Oct 2012 12:00:00 EDT

Effects of Phenoximethylpenicillin, Amoxicillin and Amoxicillin-clavulanic Acid on the Gut Microbiota

Condition:   Infectious Disease
Interventions:   Drug: Phenoxymethylpenicillin;   Drug: Amoxicillin;   Drug: Amoxicillin-clavulanic acid
Sponsor:   Uppsala University
Recruiting
Tue, 10 Sep 2019 12:00:00 EDT

Pharmacodynamic Drug Interaction Between Warfarin and Amoxicillin-clavulanic Acid

Conditions:   Oral Anticoagulation;   Deep Venous Thrombosis;   Atrial Fibrillation;   Pulmonary Embolism
Interventions:   Drug: Firstly : Amoxicillin-Clavulanic acid and secondly : Placebo;   Drug: Firstly : Placebo and secondly : Amoxicillin-Clavulanic acid
Sponsor:   Assistance Publique - Hôpitaux de Paris
Completed
Tue, 29 Jan 2008 12:00:00 EST

Moxifloxacin Versus Amoxicillin Clavulanic Acid in Treatment of Acute Exacerbation of Chronic Bronchitis

Condition:   Chronic Bronchitis
Interventions:   Drug: Avelox (Moxifloxacin, BAY12-8039);   Drug: Amoxicillin clavulanic acid
Sponsor:   Bayer
Completed
Fri, 11 Apr 2008 12:00:00 EDT

Mechanisms of Preventing Antibiotic-Associated Diarrhea and the Role for Probiotics

Condition:   Antibiotic-associated Diarrhea
Interventions:   Drug: Amoxicillin-Clavulanate 875 Mg-125 Mg Oral Tablet;   Biological: BB-12;   Other: Control
Sponsors:   Georgetown University;   National Center for Complementary and Integrative Health (NCCIH);   University of Maryland, Baltimore
Completed
Wed, 28 Nov 2018 12:00:00 EST

Exploration of microRNA and Metabolomics Biomarkers Predicting Drug Induced Liver Injury in Elderly People

Condition:   Healthy
Intervention:   Drug: Augmentin tab
Sponsor:   Seoul National University Hospital
Completed
Fri, 01 May 2015 12:00:00 EDT

Preoperative Dose of Co-amoxiclav for Prevention of Postoperative Complications in Dentoalveolar Surgery

Condition:   Infection
Interventions:   Drug: Co-Amoxiclav;   Drug: Paracetamol;   Drug: Chlorhexidine mouthwash;   Drug: Normal saline;   Drug: Amoxicillin 500 Mg;   Drug: Metronidazole
Sponsor:   Taibah University
Recruiting
Mon, 18 Feb 2019 12:00:00 EST

Amoxicillin Clavulanate in Treatment of Acute Otitis Media

Condition:   Acute Otitis Media
Interventions:   Drug: amoxicillin-clavulanate;   Drug: Placebo
Sponsors:   University of Turku;   Finnish Institute for Health and Welfare
Unknown status
Mon, 06 Mar 2006 12:00:00 EST

Comparative Study of the Safety and Efficacy of Clarithromycin Extended-Release Tablets Versus Amoxicillin-Clavulanate for the Treatment of Acute Bacterial Sinusitis

Condition:   Acute Bacterial Sinusitis (ABS)
Interventions:   Drug: Clarithromycin;   Drug: Amoxicillin
Sponsor:   Abbott
Completed
Thu, 27 Mar 2008 12:00:00 EDT

Comparing Efficacy of Postoperative Oral Antibiotic Use in Trans-Oral Thyroidectomy

Conditions:   Surgical Wound Infection;   Thyroid Nodule
Intervention:   Drug: Amoxicillin Clavulanate
Sponsor:   Seoul National University Hospital
Unknown status
Thu, 28 Sep 2017 12:00:00 EDT

Antibiotic Prophylaxis in Ragged Placental Membranes

Conditions:   Endometritis Postpartum;   Endometritis;   Membranes; Retained
Interventions:   Drug: Prophylactic antibiotics;   Other: No prophylaxis (Amox-clav withheld)
Sponsors:   Sarawak General Hospital;   University Malaysia Sarawak
Completed
Fri, 09 Mar 2018 12:00:00 EST

Intravenous Enhancin[Co-amoxiclav] Versus Postoperative Enhancin in Prevention of Postadenotonsillectomy Morbidity.

Condition:   Adenotonsillar Hypertrophy,Under 12 Years.
Intervention:   Drug: Enhancin
Sponsor:   University of Nairobi
Completed
Wed, 29 Dec 2010 12:00:00 EST

Randomized Controlled Trial Comparing Long and Short Duration of Antibiotic Prophylaxis for Patients Undergoing Sinus Lift Surgery

Condition:   Maxillofacial Surgery
Intervention:   Drug: Amoxicillin-Potassium Clavulanate Combination
Sponsor:   Tel-Aviv Sourasky Medical Center
Unknown status
Fri, 06 May 2016 12:00:00 EDT

Non-operative Management of Pediatric Appendicitis With an Appendicoltih

Condition:   Appendicitis
Intervention:   Drug: Antibiotics only (Zosyn then Augmentin)
Sponsor:   Peter Minneci
Terminated
Mon, 14 Jul 2014 12:00:00 EDT

Levofloxacin in Bacterial Rhinosinussitis

Condition:   Rhinosinusitis
Interventions:   Drug: Levofloxacin;   Drug: Amoxicillin-Potassium Clavulanate Combination
Sponsor:   Dr. Reddy's Laboratories Limited
Completed
Fri, 18 Mar 2016 12:00:00 EDT

Preschool Wheeze: Inflammation/Infection Guided Management

Condition:   Asthma
Interventions:   Drug: Beclometasone;   Drug: Co-amoxiclav;   Drug: Azithromycin
Sponsors:   Imperial College London;   National Institute for Health Research, United Kingdom
Completed
Thu, 06 Aug 2015 12:00:00 EDT

A Single, High-Dose Azithromycin Extended Release (60 mg/kg) Compared With 10 Days of High-Dose Amoxicillin Clavulanate in Children With Ear Infections at High Risk of Persistent/Recurrent Ear Infections

Condition:   Acute Otitis Media
Interventions:   Drug: amoxicillin/clavulanate postassium (Augmentin ES-600);   Drug: azithromycin SR
Sponsor:   Pfizer
Completed
Wed, 26 Mar 2008 12:00:00 EDT

Oral Steroids in Chronic Rhinosinusitis Without Nasal Polyps

Condition:   Sinusitis
Interventions:   Drug: 6 day Prednisone;   Drug: Augmentin;   Drug: 21 day Prednisone
Sponsor:   Loma Linda University
Completed
Fri, 07 Oct 2016 12:00:00 EDT

Trial on the Ideal Duration of Oral Antibiotics in Children With Pneumonia

Condition:   Pneumonia
Interventions:   Drug: Amoxicillin-Potassium Clavulanate Combination;   Drug: Placebo
Sponsors:   University of Malaya;   Menzies School of Health Research
Completed
Tue, 07 Oct 2014 12:00:00 EDT

Role of Intravenous Versus Home Oral Antibiotics in Perforated Appendicitis

Condition:   Perforated Appendicitis
Interventions:   Drug: home intravenous ertapenem;   Drug: home oral amoxicillin-clavulanate;   Device: peripheral inserted central Catheter
Sponsor:   Atrium Health
Completed
Thu, 31 Mar 2016 12:00:00 EDT

Determining the Necessity for Postoperative Antibiotics After Salivary Stent Placement

Condition:   Salivary Duct
Intervention:   Drug: Postoperative Oral Antibiotics (Clindamycin or Augmentin)
Sponsors:   Our Lady of the Lake Hospital;   Louisiana State University Health Sciences Center in New Orleans
Recruiting
Mon, 06 Nov 2017 12:00:00 EST

Short (5 Days) Versus Long (14 Days) Duration of Antimicrobial Therapy for Acute Bacterial Sinusitis in Children

Condition:   Sinusitis
Interventions:   Drug: Amoxicillin-Potassium Clavulanate Combination;   Drug: Placebo
Sponsors:   University of Wisconsin, Madison;   Thrasher Research Fund
Completed
Wed, 21 Jul 2010 12:00:00 EDT

Bioequivalence Study of an Amoxicillin-Clavulanic

Condition:   Infections, Respiratory Tract
Intervention:   Drug: 400 mg Amoxicillin + 57 mg Clavulanic Acid/ 5 ml
Sponsor:   GlaxoSmithKline
Completed
Mon, 21 Jan 2013 12:00:00 EST

Efficacy of Seven-day Combined Rabeprazole Plus Levofloxacin Plus Augmentin for Eradication of Helicobacter Pylori

Condition:   Helicobacter Pylori Infection
Interventions:   Drug: Levofloxacin-Amox/clav.;   Drug: Clarithromycin-Amoxicillin
Sponsor:   Buddhist Tzu Chi General Hospital
Terminated
Thu, 12 Apr 2012 12:00:00 EDT

Oral-only Antibiotics for Bone and Joint Infections in Children

Conditions:   Osteomyelitis;   Septic Arthritis;   Bone Infection;   Joint Infection;   Bone and Joint Infection
Interventions:   Drug: Oral co-amoxiclav or oral dicloxacillin only;   Drug: IV ceftriaxon followed by oral co-amoxiclav or oral dicloxacillin
Sponsors:   Rigshospitalet, Denmark;   The research foundation of Copenhagen University Hospital, Rigshospitalet;   Copenhagen Health Science Partners;   Innovation Fund Denmark
Recruiting
Thu, 24 Sep 2020 12:00:00 EDT

The Efficiency of Postoperative Antibiotics in Orthognathic Surgery

Condition:   Asymptomatic Diseases
Interventions:   Drug: Amoxicillin Clavulanate;   Drug: Placebo
Sponsor:   The Baruch Padeh Medical Center, Poriya
Unknown status
Fri, 15 Apr 2016 12:00:00 EDT

Prophylactic Antibiotics After Functional Endoscopic Sinus Surgery: a Randomized, Double-blind Placebo Controlled Trial

Condition:   Sinusitis
Interventions:   Drug: Amoxicillin-Potassium Clavulanate;   Drug: Placebo
Sponsor:   Massachusetts Eye and Ear Infirmary
Completed
Fri, 09 Aug 2013 12:00:00 EDT

The Evaluation of Postoperative Antibiotics in Non-Infected Mandible Fractures

Conditions:   Jaw Fractures;   Infection
Interventions:   Drug: Antibiotic treatment (Unasyn or Cleocin);   Drug: Antibiotic treatment (Augmentin or Cleocin);   Other: Control Group
Sponsor:   The University of Texas Health Science Center, Houston
Recruiting
Fri, 13 Dec 2019 12:00:00 EST

Study Comparing the Safety and Efficacy of Tigecycline With Ampicillin-Sulbactam or Amoxicillin-Clavulanate to Treat Skin Infections

Condition:   Skin Diseases, Bacterial
Interventions:   Drug: Tigecycline;   Drug: ampicillin-sulbactam
Sponsor:   Wyeth is now a wholly owned subsidiary of Pfizer
Completed
Thu, 24 Aug 2006 12:00:00 EDT

Study the Efficacy of Topical Antibiotherapy in the Prophylaxis of Incisional Surgical Infection in Urgent Surgery

Conditions:   Surgical Wound Infection;   Postoperative Wound Infection;   Postoperative Wound Infection Superficial Incisional;   Preventive Therapy
Interventions:   Drug: Amoxicillin Clavulanate;   Drug: Physiological Saline
Sponsors:   Universitat Internacional de Catalunya;   Hospital de Granollers
Unknown status
Fri, 29 Jun 2018 12:00:00 EDT

Use of Perioperative Antibiotics in Endoscopic Sinus Surgery

Condition:   Chronic Sinus Infection
Intervention:   Drug: Amoxi Clavulanate
Sponsor:   Montefiore Medical Center
Suspended
Tue, 12 Dec 2017 12:00:00 EST

AUGMENTIN 1gm In Skin And Soft Tissue Infection

Conditions:   Skin Diseases, Infectious;   Infection, Soft Tissue
Intervention:   Drug: amoxicillin/clavulanate potassium 1gm
Sponsor:   GlaxoSmithKline
Completed
Thu, 22 Jun 2006 12:00:00 EDT

Effects of S. Boulardii and Amoxicillin/Clavulanate on Gut Microbiota

Condition:   Healthy Volunteers
Interventions:   Dietary Supplement: Saccharomyces boulardii;   Drug: Amoxicillin Clavulanate
Sponsors:   Beth Israel Deaconess Medical Center;   Biocodex
Completed
Thu, 17 Nov 2011 12:00:00 EST

Effect of Irrigation With Antibiotic-containing Solutions on Postoperative Pain and Intra-canal Bacteria

Condition:   Necrotic Pulp
Interventions:   Combination Product: co-amoxiclav-clindamycin solution;   Combination Product: MTAD;   Combination Product: 2.5% sodium hypochlorite
Sponsor:   Cairo University
Not yet recruiting
Mon, 29 Jul 2019 12:00:00 EDT

Antibiotic PRophylAxis Based on infeCTIve Risk in Cardiac Implantable Electronic Device

Condition:   Device Related Infection
Intervention:   Drug: amoxicillin clavulanate
Sponsor:   University Hospital of Ferrara
Completed
Wed, 03 Feb 2021 12:00:00 EST

Prospective Randomized Study: Assessment of PRF Efficacy in Prevention of Jaw Osteonecrosis After Tooth Extraction

Condition:   Bisphosphonate-Associated Osteonecrosis of the Jaw
Interventions:   Drug: tooth extraction with antibiotics (amoxicillin- clavulanate, clindamycine);   Procedure: atraumatic extraction
Sponsor:   Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Unknown status
Wed, 23 Jul 2014 12:00:00 EDT

Bacteriological Study of Acute Follicular Tonsillitis

Condition:   Acute Follicular Tonsillitis
Intervention:   Drug: Amoxicillin Clavulanate
Sponsor:   Assiut University
Not yet recruiting
Wed, 25 Mar 2020 12:00:00 EDT

Mechanisms of Probiotics and Antibiotic-Associated Diarrhea

Condition:   Antibiotic-associated Diarrhea
Interventions:   Drug: Amoxicillin-Clavulanate 875 Mg-125 Mg Oral Tablet;   Biological: BB-12;   Other: Control
Sponsors:   Georgetown University;   National Center for Complementary and Integrative Health (NCCIH);   University of Maryland, Baltimore;   Penn State University
Recruiting
Thu, 04 Jun 2020 12:00:00 EDT

A Study to Assess the Safety, Tolerability and Efficacy of OP0201 as an Adjunct Treatment for Acute Otitis Media in Infants and Children Aged 6 to 24 Months

Condition:   Acute Otitis Media
Interventions:   Combination Product: OP0201;   Combination Product: Placebo;   Drug: Amoxicillin-clavulanate
Sponsor:   Novus Therapeutics, Inc
Completed
Mon, 28 Jan 2019 12:00:00 EST

Study to Assess the Efficacy and Safety of Potassium Clavulanate/Amoxicillin in Children With Acute Bacterial Rhinosinusitis

Condition:   Sinusitis, Acute
Intervention:   Drug: Amoxicillin-Potassium Clavulanate Combination
Sponsor:   GlaxoSmithKline
Completed
Wed, 04 Sep 2013 12:00:00 EDT

Antibiotic Therapy in Erupted Tooth Extractions

Conditions:   Tooth Extraction;   Post-Op Complication;   Amoxicillin
Interventions:   Drug: Amoxicillin Clavulanate;   Dietary Supplement: Bifidobacterium longum and Lactoferrin
Sponsor:   Antonio Barone
Completed
Mon, 09 Sep 2019 12:00:00 EDT

Antibiotics for Severe Perineal Laceration to Prevent Infection Following Repair

Condition:   Vaginal Laceration During Delivery
Interventions:   Drug: Augmentin/Flagyl or Augmentin/Clindamycin;   Drug: Placebo
Sponsor:   Northwestern University
Recruiting
Mon, 05 Oct 2020 12:00:00 EDT

Duration of Antibiotic Therapy as Part of Maximal Medical Therapy for Chronic Rhinosinusitis

Condition:   Sinusitis
Interventions:   Drug: Doxycycline;   Drug: Azithromycin;   Drug: Augmentin
Sponsor:   University of North Carolina, Chapel Hill
Completed
Fri, 05 Apr 2013 12:00:00 EDT

Target Attainment and Pharmacokinetics of Antimicrobials in Non-critically Ill Surgery Patients (TAPAS)

Condition:   Surgery
Intervention:   Drug: amoxicillin-clavulanic acid
Sponsor:   Universitaire Ziekenhuizen Leuven
Unknown status
Wed, 19 Apr 2017 12:00:00 EDT

Initial Antibiotics and Delayed Appendectomy for Acute Appendicitis

Condition:   Acute Appendicitis
Intervention:   Drug: Piperacillin + Amoxicillin
Sponsor:   Rhode Island Hospital
Completed
Tue, 02 Oct 2012 12:00:00 EDT

Effect of Lactobacillus Reuteri DSM 17938 to Prevent Antibiotic-associated Diarrhea in Children

Condition:   Antibiotic Associated Diarrhea
Interventions:   Drug: Lactobacillus reuteri DSM 17938;   Drug: Placebo;   Drug: Amoxicillin-Clavulanic Acid
Sponsors:   Eskisehir Osmangazi University;   Hacettepe University;   Acıbadem University School of Medicine;   Umraniye Education and Research Hospital;   Sisli Hamidiye Etfal Training and Research Hospital;   Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization;   Ege University Medical School;   Yuzuncu Yıl University;   Goztepe Training and Research Hospital;   Erzurum Regional Training & Research Hospital;   Namik Kemal University
Completed
Fri, 06 May 2016 12:00:00 EDT

Pharmacokinetic Profiles Of Amoxicillin 2000 mg And Clavulanate 125 mg In Adolescent Patients

Condition:   Infections, Respiratory Tract
Intervention:   Drug: amoxicillin/clavulanate potassium
Sponsor:   GlaxoSmithKline
Completed
Thu, 20 Jul 2006 12:00:00 EDT

An Oral Amoxicillin-Clavulanate Regimen to Prevent Bacteremia Following Dental Procedures

Conditions:   Bacteraemia;   Endocarditis
Interventions:   Drug: Amoxicillin;   Drug: Amoxicillin-Potassium Clavulanate
Sponsors:   University of Santiago de Compostela;   Hospital Clinico Universitario de Santiago
Recruiting
Thu, 26 May 2016 12:00:00 EDT

Efficacy of Tympanostomy Tubes for Children With Recurrent Acute Otitis Media

Condition:   Acute Otitis Media
Interventions:   Device: Tympanostomy tube placement;   Drug: Amoxicillin-Clavulanate and/or Ceftriaxone;   Drug: Ofloxacin Otic
Sponsors:   Alejandro Hoberman;   George Washington University;   National Institute on Deafness and Other Communication Disorders (NIDCD)
Completed
Mon, 05 Oct 2015 12:00:00 EDT

Quadruple Therapy for Triple Therapy Resistant Helicobacter Pylori Infection

Condition:   Treatment of Helicobacter Pylori
Interventions:   Drug: Augmentin (Amoxicillin-clavulanic);   Drug: Furoxone (furazolidone);   Drug: Cebes (colloidal bismuth subcitrate);   Drug: Esso (esomeprazole)
Sponsor:   Aga Khan University
Completed
Mon, 27 Aug 2007 12:00:00 EDT

Sulopenem Followed by Sulopenem-etzadroxil/Probenecid vs Ertapenem Followed by Cipro for Complicated UTI in Adults

Condition:   Complicated Urinary Tract Infections
Interventions:   Drug: Sulopenem;   Drug: Sulopenem-Etzadroxil/Probenecid;   Drug: Ertapenem;   Drug: Ciprofloxacin;   Drug: Amoxicillin-clavulanate
Sponsor:   Iterum Therapeutics, International Limited
Completed
Thu, 30 Nov 2017 12:00:00 EST

Antibiotic Duration in Post-appendectomy Abscess

Conditions:   Complicated Appendicitis;   Perforated Appendicitis
Intervention:   Drug: ampicillin/clavulanate
Sponsor:   Phoenix Children's Hospital
Unknown status
Mon, 07 Jan 2019 12:00:00 EST

Special Drug Use Investigation for CLAVAMOX® (Amoxicillin/Clavulanate) Pediatrics Dry Syrup (Every Indication Excluded Otitis Media)

Condition:   Otitis Maedia
Intervention:   Drug: Amoxicillin and clavulanate
Sponsor:   GlaxoSmithKline
Completed
Mon, 01 Aug 2011 12:00:00 EDT

Effect of Preoperative Amoxicillin/Clavulanic Acid Combination on Postoperative Endodontic Pain

Condition:   Symptomatic Periapical Periodontitis
Interventions:   Drug: Amoxicillin/Clavulanate Potassium 875 mg-125 mg oral tablet;   Drug: Oral placebo
Sponsor:   Cairo University
Completed
Thu, 26 Jan 2017 12:00:00 EST

Benefit of a Single Preoperative Dose of Antibiotics for the Prevention of Surgical Site Infections

Condition:   Surgical Site Infection
Intervention:   Drug: Amoxicillin/Clavulanic Acid
Sponsors:   Swiss Tropical & Public Health Institute;   Swiss Academy of Medical Sciences (SAMS)
Completed
Wed, 03 Dec 2008 12:00:00 EST

A Multicentre, Randomised, Open-Label Study To Compare The Efficacy And Safety Of Azithromycin For 5 Days With Those Of Amoxicillin-Clavulanic Acid In Patients With Chronic Bronchitis

Condition:   Bronchitis, Chronic
Interventions:   Drug: Amoxicillin/clavulinic acid;   Drug: Azithromycin
Sponsor:   Pfizer
Completed
Tue, 01 Apr 2008 12:00:00 EDT

Do Antibiotics Prevent Anal Fistulae Formation?

Condition:   Anal Fistula
Interventions:   Drug: Amoxicillin-Clavulanate;   Drug: Placebo
Sponsor:   Ankara University
Completed
Fri, 13 Nov 2009 12:00:00 EST

Reduction of Intravenous Antibiotics In Neonates

Conditions:   Neonatal Infection;   Neonatal SEPSIS
Interventions:   Drug: Amoxicillin Clavulanate;   Drug: Antibiotics
Sponsors:   Franciscus Gasthuis;   Erasmus Medical Center
Completed
Mon, 14 Aug 2017 12:00:00 EDT

600 mg Amoxicillin/42.9 mg Clavulanate Postassium /5 mL Suspension Under Fed Conditions

Condition:   Healthy
Interventions:   Drug: 600 mg Amoxicillin/42.9 mg Clavulanate Postassium /5 mL;   Drug: Augmentin ES-600™
Sponsor:   Teva Pharmaceuticals USA
Completed
Tue, 10 Feb 2009 12:00:00 EST

Whole Blood Bactericidal Activity (WBA) Against Mycobacterium Tuberculosis of Faropenem Plus Amoxicillin/Clavulanic Acid in Healthy Volunteers

Condition:   Tuberculosis
Interventions:   Drug: Faropenem;   Drug: Amoxicillin/clavulanic acid 500mg/125mg;   Drug: Rifampicin
Sponsor:   National University Hospital, Singapore
Completed
Thu, 19 Mar 2015 12:00:00 EDT

Antibiotherapy During Therapeutic Hypothermia to Prevent Infectious Complications

Conditions:   Ventilator-associated Pneumonia;   Cardiac Arrests With Shockable Rhythm;   Mild Therapeutic Hypothermia;   Preventive Antibiotics
Interventions:   Drug: Amoxicillin - clavulanic acid;   Drug: Placebo
Sponsor:   University Hospital, Limoges
Completed
Thu, 10 Jul 2014 12:00:00 EDT

600 mg Amoxicillin/42.9 mg Clavulanate Postassium /5 mL Suspension Under Fasting Conditions

Condition:   Healthy
Interventions:   Drug: 600 mg Amoxicillin/42.9 mg Clavulanate Postassium /5 mL;   Drug: Augmentin ES-600™ 600 mg/42.9 mg/5 mL Suspension
Sponsor:   Teva Pharmaceuticals USA
Completed
Tue, 10 Feb 2009 12:00:00 EST

The Amputation Surgical Site Infection Trial (ASSIT)

Conditions:   Wound Infection;   Amputation Wound
Interventions:   Drug: Co-amoxiclav;   Drug: Iodine;   Drug: Metronidazole;   Drug: Chlorhexidine;   Drug: Teicoplanin;   Drug: Clindamycin
Sponsors:   Hull University Teaching Hospitals NHS Trust;   University of Hull
Completed
Mon, 23 Dec 2013 12:00:00 EST

Bacteriology and Inflammation in Bronchiectasis

Condition:   Bronchiectasis
Interventions:   Drug: Fluroquinolones;   Drug: Beta-lactamase inhibitor
Sponsor:   Guangzhou Institute of Respiratory Disease
Recruiting
Fri, 04 Jan 2013 12:00:00 EST

Sulopenem Versus Ertapenem for Complicated Intra-abdominal Infection (cIAI)

Condition:   Intra Abdominal Infections
Interventions:   Drug: Ertapenem;   Drug: Sulopenem-Etzadroxil/Probenecid;   Drug: Ciprofloxacin;   Drug: Metronidazole;   Drug: Amoxicillin-Clavulanate;   Drug: Sulopenem
Sponsor:   Iterum Therapeutics, International Limited
Completed
Thu, 30 Nov 2017 12:00:00 EST

Safety and Efficacy Study of Ceftaroline Versus a Comparator in Pediatric Subjects With Community Acquired Bacterial Pneumonia (CABP)

Conditions:   Infections;   Community Acquired Pneumonia
Interventions:   Drug: Ceftaroline fosamil;   Drug: Ceftriaxone;   Drug: amoxicillin clavulanate
Sponsors:   Forest Laboratories;   AstraZeneca
Completed
Fri, 10 Feb 2012 12:00:00 EST

Antibiotic Prophylaxis and Renal Damage In Congenital Abnormalities of the Kidney and Urinary Tract

Conditions:   Vesicoureteral Reflux;   Renal Hypodysplasia, Nonsyndromic, 1;   Chronic Kidney Disease
Interventions:   Drug: nitrofurantoin;   Other: No prophylaxis;   Drug: Amoxicillin-Potassium Clavulanate Combination;   Drug: Trimethoprim/sulfamethoxazole;   Drug: Cefixime
Sponsors:   Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico;   Ministero della Salute, Italy;   IL Sogno di Stefano
Active, not recruiting
Fri, 27 Dec 2013 12:00:00 EST

Early-onset Ventilator-associated Pneumonia in Adults: Comparison of 8 Versus 15 Days of Antibiotic Treatment

Condition:   Pneumonia Ventilator Associated
Interventions:   Drug: Augmentin, Ceftriaxone, Cefotaxime, netilmycin, tobramycin;   Drug: compare 8 to15 days of antibiotic treatment
Sponsors:   Centre Hospitalier Universitaire de Besancon;   French Society for Intensive Care;   SmithKline Beecham;   GlaxoSmithKline
Completed
Wed, 21 Mar 2012 12:00:00 EDT

Short Post-surgical Antibiotic Therapy in Spine Infections - a Prospective, Randomized, Unblinded, Non-inferiority Trial

Condition:   Infection
Intervention:   Drug: duration of standard antibiotic therapy
Sponsor:   Balgrist University Hospital
Recruiting
Wed, 07 Aug 2019 12:00:00 EDT

Trial to Evaluate Beta-Lactam Antimicrobial Therapy of Community Acquired Pneumonia in Children

Condition:   Pneumonia
Interventions:   Drug: Amoxicillin;   Drug: Amoxicillin-clavulanate;   Drug: Cefdinir;   Other: Placebo
Sponsor:   National Institute of Allergy and Infectious Diseases (NIAID)
Completed
Thu, 08 Sep 2016 12:00:00 EDT

Bioequivalence Study of Amoxicillin 400 mg/Clavulanic Acid 57 mg Chewable Tablets Under Fasting Conditions

Condition:   Healthy
Intervention:   Drug: amoxicillin 400mg + clovalunic acid 57.5mg tablets
Sponsor:   Ranbaxy Laboratories Limited
Completed
Thu, 23 Oct 2008 12:00:00 EDT

Effect of Vitamin D on Drug Resistant Helicobacter Pylori (HP) Eradication Study

Condition:   H. Pylori Infection
Interventions:   Drug: Esomeprazole;   Drug: Amoxicillin-Potassium Clavulanate Combination;   Drug: Clarithromycin;   Drug: Vitamin D3
Sponsor:   Chinese University of Hong Kong
Unknown status
Fri, 05 May 2017 12:00:00 EDT

AUGMENTIN™ in Dental Infections

Condition:   Focal Infection, Dental
Interventions:   Drug: Amoxicillin/clavulanate;   Drug: Clindamycin
Sponsor:   GlaxoSmithKline
Completed
Mon, 19 May 2014 12:00:00 EDT

Zmax Compared to Augmentin in Sinusitis

Condition:   Sinusitis
Interventions:   Drug: Azithromycin Extended Release;   Drug: Amoxicillin/Clavulanate
Sponsor:   Pfizer
Completed
Tue, 22 Aug 2006 12:00:00 EDT

Monotherapy Versus Bitherapy in Non-severe Hospitalized Community-acquired Pneumonia

Condition:   Community-acquired Pneumonia
Interventions:   Drug: Beta lactam (amoxicillin / clav. acid OR cefuroxime);   Drug: Beta-lactam (amoxicillin / clav. acid OR cefuroxime) AND macrolide (clarithromycin)
Sponsors:   Swiss National Fund for Scientific Research;   University Hospital, Geneva
Completed
Wed, 07 Jan 2009 12:00:00 EST

A Study to Compare Different Antibiotics and Different Modes of Fluid Treatment for Children With Severe Pneumonia

Condition:   Pneumonia
Interventions:   Drug: Benzyl penicillin;   Drug: Gentamicin Sulfate;   Drug: Ceftriaxone;   Drug: Amoxicillin Clavulanate;   Other: Intravenous fluid;   Other: Nasogastric feeds;   Drug: Ampicillin
Sponsors:   University of Oxford;   University of Nairobi;   London School of Hygiene and Tropical Medicine;   National Institute for Health Research, United Kingdom;   Department for International Development, United Kingdom;   Medical Research Council;   Wellcome Trust;   Kenya Ministry of Health
Suspended
Thu, 01 Aug 2019 12:00:00 EDT

Culture-guided Antimicrobial Prophylaxis in Men Undergoing Prostate Biopsy.

Conditions:   Complication;   Infection;   Prostate Cancer
Interventions:   Drug: Ciprofloxacin;   Drug: Trimethoprim/Sulfamethoxazole;   Drug: Fosfomycin;   Drug: Pivmecillinam/augmentin
Sponsors:   Radboud University;   ZonMw: The Netherlands Organisation for Health Research and Development
Active, not recruiting
Mon, 24 Jul 2017 12:00:00 EDT

Short Duration Treatment of Non-severe Community Acquired Pneumonia

Condition:   Community Acquired Pneumonia
Interventions:   Radiation: Chest X-ray;   Biological: blood sampling /Cell Counts/ C reactive protein (CRP)/Biochemistry;   Drug: Augmentin;   Drug: Placebo (for Augmentin);   Drug: Beta-Lactams
Sponsor:   Versailles Hospital
Unknown status
Wed, 16 Oct 2013 12:00:00 EDT

Systemic Methylprednisolone in Chronic Rhinosinusitis

Conditions:   Chronic Rhinosinusitis;   Children
Intervention:   Drug: methylprednisolone
Sponsor:   Ondokuz Mayıs University
Completed
Tue, 21 Sep 2010 12:00:00 EDT

Conservative Versus Operative ManageMent of Acute Uncomplicated Appendicitis

Condition:   Appendicitis
Interventions:   Procedure: Laparoscopic +/- Open Appendicectomy;   Drug: Antibiotic treatment
Sponsor:   Beaumont Hospital
Completed
Tue, 27 Sep 2016 12:00:00 EDT

A Study Of Intravenous Sulopenem And Oral PF-03709270 In Community Acquired Pneumonia That Requires Hospitalization

Condition:   Pneumonia, Bacterial
Interventions:   Drug: sulopenem and PF-03709270;   Drug: Sulopenem and PF-03709270;   Drug: Ceftriaxone and amoxicillin/clavulanate
Sponsor:   Pfizer
Completed
Tue, 25 Nov 2008 12:00:00 EST

Trial of Faropenem and Cefadroxil (in Combination With Amoxicillin/Clavulanic Acid and Standard TB Drugs) in Patients With Pulmonary Tuberculosis: Measurement of Early Bactericidal Activity and Effects on Novel Biomarkers

Condition:   Pulmonary Tuberculosis
Interventions:   Drug: Faropenem;   Drug: Amoxicillin/clavulanic acid;   Drug: Cefadroxil;   Drug: Rifampicin
Sponsor:   National University Hospital, Singapore
Completed
Fri, 06 Mar 2015 12:00:00 EST

Early Hospital Discharge or Standard Inpatient Care in Cancer Patients Receiving Antibiotics for Febrile Neutropenia

Conditions:   Brain and Central Nervous System Tumors;   Lymphoma;   Neutropenia;   Psychosocial Effects of Cancer and Its Treatment;   Small Intestine Cancer;   Unspecified Adult Solid Tumor, Protocol Specific
Interventions:   Drug: amoxicillin-clavulanate potassium;   Drug: ciprofloxacin;   Procedure: psychosocial assessment and care;   Procedure: quality-of-life assessment
Sponsor:   Clatterbridge Centre for Oncology
Unknown status
Fri, 09 Mar 2007 12:00:00 EST

Sputum Microbiota and the Association With Clinical Parameters in Steady-state, Acute Exacerbation and Convalescence of Bronchiectasis

Condition:   Bronchiectasis
Intervention:   Drug: Antibiotics
Sponsor:   Guangzhou Institute of Respiratory Disease
Recruiting
Fri, 12 Dec 2014 12:00:00 EST

Probiotic Product in Healthy Adults Undergoing Antibiotic Treatment

Condition:   Antibiotic Therapy
Interventions:   Dietary Supplement: Probiotic;   Dietary Supplement: Placebo
Sponsors:   Danisco;   KGK Science Inc.
Completed
Fri, 17 Aug 2012 12:00:00 EDT

Bioequivalence Study of Amoxicillin 400 mg/Clavulanic Acid 57 mg Chewable Tablets Under Fed Conditions

Condition:   Healthy
Intervention:   Drug: Amoxicillin 400mg + clovalunic acid 57.5mg chewable tablets
Sponsor:   Ranbaxy Laboratories Limited
Completed
Thu, 23 Oct 2008 12:00:00 EDT

CHOOSE : Telithromycin, Acute Bacterial Sinusitis

Condition:   Sinusitis
Intervention:   Drug: Telithromycin
Sponsor:   Sanofi
Completed
Thu, 15 Sep 2005 12:00:00 EDT

Effectiveness of Intravenous Immunoglobulins (IVIG) in Toxic Shock Syndromes in Children

Conditions:   Staphylococcal Infection;   Streptococcal Infection
Interventions:   Drug: PRIVIGEN (CSL Behring);   Drug: Albumin
Sponsor:   Hospices Civils de Lyon
Withdrawn
Wed, 14 Sep 2016 12:00:00 EDT

Efficacy of Surgical Treatment of Osteomyelitis in Diabetic Foot Ulcers

Conditions:   Osteomyelitis;   Diabetic Foot;   Diabetic Foot Ulcers
Interventions:   Procedure: Conservative surgery;   Drug: Ciprofloxacin;   Drug: Amoxicillin-Potassium Clavulanate Combination;   Drug: Sulfamethoxazole trimethoprim
Sponsor:   Universidad Complutense de Madrid
Unknown status
Mon, 07 Jun 2010 12:00:00 EDT

Antibiotic Dosing in Geriatric Patients at the Emergency Department

Conditions:   Elderly Infection;   Frailty;   Frail Elderly Syndrome;   Infection, Bacterial
Interventions:   Diagnostic Test: Blood sampling;   Diagnostic Test: Sputum sample;   Diagnostic Test: Hemoculture;   Diagnostic Test: Urine sample
Sponsor:   University Hospital, Ghent
Recruiting
Thu, 18 Jun 2020 12:00:00 EDT

Moxifloxacin Compared With Ciprofloxacin/Amoxicillin in Treating Fever and Neutropenia in Patients With Cancer

Conditions:   Chronic Myeloproliferative Disorders;   Fever, Sweats, and Hot Flashes;   Infection;   Leukemia;   Lymphoma;   Multiple Myeloma and Plasma Cell Neoplasm;   Myelodysplastic Syndromes;   Myelodysplastic/Myeloproliferative Neoplasms;   Neutropenia;   Precancerous Condition;   Unspecified Adult Solid Tumor, Protocol Specific
Interventions:   Drug: amoxicillin-clavulanate potassium;   Drug: ciprofloxacin;   Drug: moxifloxacin hydrochloride;   Procedure: management of therapy complications
Sponsor:   European Organisation for Research and Treatment of Cancer - EORTC
Terminated
Fri, 06 Jun 2003 12:00:00 EDT

The Use of Prophylactic Antibiotics in Endoscopy Sinus Surgery for Chronic Rhinosinusitis With or Without Polyp

Condition:   Chronic Sinus Infection
Interventions:   Drug: Amoxicillin / Clavulanic acid 875mg / 125mg;   Drug: Placebos
Sponsor:   CHU de Quebec-Universite Laval
Recruiting
Fri, 18 Jan 2019 12:00:00 EST

Phase I Study of Safety and Immunogenicity of ADU-623

Conditions:   Astrocytic Tumors;   Glioblastoma Multiforme;   Anaplastic Astrocytoma;   Brain Tumor
Interventions:   Biological: Cohort 1;   Biological: Cohort 2;   Biological: Cohort 3;   Drug: Antibiotics
Sponsors:   Providence Health & Services;   Aduro Biotech, Inc.
Completed
Wed, 23 Oct 2013 12:00:00 EDT

Effect of Antimicrobial Treatment of Acute Otitis Media on the Intestinal Microbiome in Children

Condition:   Acute Otitis Media
Interventions:   Drug: Amoxicillin;   Drug: Amoxicillin-Potassium Clavulanate;   Drug: Macrolide
Sponsors:   University of Oulu;   Oulu University Hospital
Unknown status
Mon, 17 Oct 2016 12:00:00 EDT

A Trial Comparing Two Modalities of Prophylactic Nutritional Support During Treatment for Head and Neck Cancer

Condition:   Head and Neck Neoplasms
Interventions:   Procedure: percutaneous endoscopic gastrostomy tube placement;   Procedure: nasogastric tube placement
Sponsor:   Shaukat Khanum Memorial Cancer Hospital & Research Centre
Unknown status
Fri, 15 Nov 2013 12:00:00 EST

Clinical Trial Corticoids For Empyema And Pleural Effusion In Children

Conditions:   Parapneumonic Pleural Effusion;   Empyema
Interventions:   Drug: Dexamethasone;   Drug: Placebo
Sponsors:   Hospital Infanta Sofia;   Pediatrics Spanish Association (Madrid and Castilla-La Mancha Pediatric Association);   Spanish Ministry of Health.
Completed
Thu, 16 Dec 2010 12:00:00 EST

Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired Pneumonia

Condition:   Community-acquired Pneumonia, Influenza, COVID-19
Interventions:   Drug: Fixed-duration Hydrocortisone;   Drug: Shock-dependent hydrocortisone;   Drug: Ceftriaxone;   Drug: Moxifloxacin or Levofloxacin;   Drug: Piperacillin-tazobactam;   Drug: Ceftaroline;   Drug: Amoxicillin-clavulanate;   Drug: Macrolide administered for 3-5 days;   Drug: Macrolide administered for up to 14 days;   Drug: Five-days oseltamivir;   Drug: Ten-days oseltamivir;   Drug: Lopinavir/ritonavir;   Drug: Hydroxychloroquine;   Drug: Hydroxychloroquine + lopinavir/ritonavir;   Drug: Interferon-β1a;   Drug: Anakinra;   Drug: Fixed-duration higher dose Hydrocortisone;   Drug: Tocilizumab;   Drug: Sarilumab;   Drug: Vitamin C;   Drug: Therapeutic anticoagulation;   Drug: Simvastatin;   Biological: Convalescent plasma;   Other: Protocolised mechanical ventilation strategy;   Drug: Eritoran;   Drug: Apremilast;   Drug: Aspirin;   Drug: Clopidogrel;   Drug: Prasugrel;   Drug: Ticagrelor
Sponsors:   MJM Bonten;   Australian and New Zealand Intensive Care Research Centre;   Medical Research Institute of New Zealand;   Unity Health;   Berry Consultants;   Global Coalition for Adaptive Research;   University of Pittsburgh Medical Center
Recruiting
Wed, 13 Apr 2016 12:00:00 EDT

Safety and Efficacy of Solithromycin in Adolescents and Children With Community-Acquired Bacterial Pneumonia

Condition:   Community-acquired Bacterial Pneumonia
Interventions:   Drug: Solithromycin;   Drug: Standard of Care
Sponsors:   Melinta Therapeutics, Inc.;   Biomedical Advanced Research and Development Authority
Terminated
Mon, 16 Nov 2015 12:00:00 EST

Empirical vs 2nd Line Antibiotic Therapy in Health-care Associated Infections in Cirrhosis

Condition:   Cirrhosis
Interventions:   Drug: Imipenem;   Drug: Vancomycin;   Drug: azithromycin;   Drug: Cefotaxime;   Drug: Amoxicillin
Sponsor:   University of Roma La Sapienza
Unknown status
Thu, 28 Mar 2013 12:00:00 EDT

Antibiotic Dosing in Pediatric Intensive Care

Conditions:   Pharmacokinetics;   Amoxicillin-clavulanate;   Piperacillin-tazobactam;   Vancomycin;   Teicoplanin;   Meropenem;   Ciprofloxacin;   Amikacin
Interventions:   Procedure: blood sampling in patients receiving amoxicillin-clavulanate as part of routine clinical care;   Procedure: blood sampling in patients receiving piperacilline-tazobactam as part of routine clinical care.;   Procedure: blood sampling in patients receiving vancomycin as part of routine clinical care.;   Procedure: blood sampling in patients receiving teicoplanin as part of routine clinical care.;   Procedure: blood sampling in patients receiving meropenem as part of routine clinical care.;   Procedure: blood sampling and urine smapling in patients receiving ciprofloxacin as part of routine clinical care.;   Procedure: blood sampling in patients receiving amikacin as part of routine clinical care.
Sponsors:   University Hospital, Ghent;   University Hospital, Antwerp;   Queen Fabiola Children's University Hospital, Brussels
Unknown status
Fri, 29 May 2015 12:00:00 EDT

Efficacy of Antibiotic Therapy in Severe Alcoholic Hepatitis Treated With Prednisolone

Conditions:   Alcoholic Hepatitis;   Alcoholic Liver Disease
Interventions:   Drug: Amoxicillin;   Drug: Placebo;   Drug: Prednisolone
Sponsors:   University Hospital, Lille;   Ministry of Health, France
Completed
Tue, 04 Nov 2014 12:00:00 EST

Evaluating the EBA of Meropenem With Amoxicillin/Clavulanate and Pyrazinamide or Bedaquiline in Adults With PTB

Condition:   Tuberculosis
Interventions:   Drug: Meropenem Injection;   Drug: Amoxicillin Clavulanate;   Drug: Pyrazinamide;   Drug: Bedaquiline;   Drug: Rifafour
Sponsor:   TASK Applied Science
Recruiting
Mon, 16 Nov 2020 12:00:00 EST

Safety and Efficacy Study of Ceftaroline Versus a Comparator in Pediatric Subjects With Complicated Community Acquired Pneumonia (CABP)

Conditions:   Infections;   Pneumonia
Interventions:   Drug: Ceftaroline fosamil;   Drug: IV Ceftriaxone and Vancomycin
Sponsor:   Forest Laboratories
Completed
Tue, 21 Aug 2012 12:00:00 EDT

Short Post-operative Antibacterial Therapy in Complicated Appendicitis: Oral Versus Intravenous

Conditions:   Acute Appendicitis;   Acute Appendicitis With Rupture;   Acute Appendicitis Without Peritonitis;   Acute Appendicitis With Appendix Abscess;   Appendicitis; Perforation;   Appendicitis Perforated;   Appendicitis Acute
Intervention:   Other: Oral versus intravenous administration of antibacterial treatment
Sponsors:   North Estonia Medical Centre;   Tartu University Hospital
Recruiting
Thu, 01 Jul 2021 12:00:00 EDT

The HYsteroscopic Miscarriage MaNagement Trial: A Pilot RCT Investigating a Novel Management Pathway for RPOC

Condition:   Retained Products After Miscarriage
Interventions:   Procedure: Outpatient hysteroscopy;   Behavioral: Expectant management;   Drug: Medical management;   Drug: Antibiotic;   Procedure: Surgical management
Sponsors:   Birmingham Women's and Children's NHS Foundation Trust;   Tommy's
Recruiting
Fri, 12 Feb 2021 12:00:00 EST

Antibiotics Use and Carriage of Methicillin-resistant Staphylococci in Community Patients

Condition:   Methicillin Resistant Staphylococcus Aureus
Intervention:  
Sponsor:   Assistance Publique - Hôpitaux de Paris
Completed
Mon, 12 Dec 2011 12:00:00 EST

Early Bactericidal Activity of Rifampin + Meropenem + Amoxicillin/Clavulanate in Adults With Pulmonary TB

Condition:   Tuberculosis, Pulmonary
Interventions:   Drug: Rifampin;   Drug: MEROPENEM 2 grams TID;   Drug: MEROPENEM 1 gram TID;   Drug: MEROPENEM 3 grams QD;   Drug: Amoxicillin/Clavulanate Potassium 500 MG-125 MG Oral Tablet;   Drug: Amoxicillin/Clavulanate Potassium 875 MG-125 MG Oral Tablet
Sponsor:   Johns Hopkins University
Recruiting
Fri, 02 Jun 2017 12:00:00 EDT

Pharmacokinetics and Safety of Antimicrobial Agents Administered by Subcutaneous Route in Patients AGEd Over 65 Years

Conditions:   Antimicrobials;   Subcutaneous Injection;   Antibiotic;   Older People
Interventions:   Drug: Subcutaneous (SC) route for antibiotic treatment;   Drug: Intravenous (IV) route for antibiotic treatment
Sponsor:   University Hospital, Bordeaux
Recruiting
Wed, 11 Jul 2018 12:00:00 EDT

Short-term Antibiotic Treatment for Unexplained Fever in Solid Cancer Patients With Febrile Neutropenia

Condition:   Febrile Neutropenia
Interventions:   Other: Early antibiotic discontinuation;   Other: Usual practice
Sponsor:   Rabin Medical Center
Withdrawn
Wed, 12 Oct 2011 12:00:00 EDT

Maxillary Sinus Irrigation in the Management of Chronic Rhinosinusitis

Condition:   Sinusitis
Interventions:   Procedure: Maxillary Sinus Irrigation;   Drug: IV Amoxicillin and Clavulanate acid
Sponsor:   Ohad Ronen
Completed
Fri, 09 Jun 2006 12:00:00 EDT

Effects of Advair® in Outpatients With Chronic Obstructive Pulmonary Disease (COPD) Acute Exacerbation

Condition:   Chronic Obstructive Pulmonary Disease (COPD)
Interventions:   Drug: prednisone group;   Drug: Advair group
Sponsors:   Laval University;   GlaxoSmithKline
Completed
Wed, 19 Sep 2007 12:00:00 EDT

Patients Response to Early Switch To Oral:Osteomyelitis Study

Condition:   Osteomyelitis
Interventions:   Drug: oral antibiotics;   Procedure: intravenous antibiotics
Sponsors:   Julio Ramirez;   University of Louisville
Terminated
Fri, 28 Mar 2014 12:00:00 EDT

Pharmacokinetic Study of the Association of Amoxicillin / Clavulanic Acid to Obese Adults

Condition:   Obesity
Intervention:   Drug: amoxicillin and clavulanic acid
Sponsor:   Institut de Médecine et d'Epidémiologie Appliquée - Fondation Internationale Léon M'Ba
Completed
Thu, 08 Oct 2015 12:00:00 EDT

Antibiotic Concentrations Among Critically Ill Patients

Condition:   Administration of Antibiotics in Intensive Care Units
Intervention:   Biological: Blood sampling
Sponsor:   Centre Hospitalier Universitaire de Nīmes
Completed
Fri, 02 Mar 2012 12:00:00 EST

Comparative Effectiveness of Antibiotics for Respiratory Infections

Conditions:   Acute Otitis Media;   Acute Sinusitis;   Group A Streptococcal Pharyngitis
Interventions:   Drug: Broad-spectrum antibiotics;   Drug: Narrow-spectrum antibiotics
Sponsor:   Children's Hospital of Philadelphia
Completed
Fri, 21 Nov 2014 12:00:00 EST

Comparison of a Serum PRO-CT Guided Treatment and the Recommended Antibiotic Treatment for COPD

Condition:   Chronic Obstructive Pulmonary Disease
Intervention:   Other: PRO-CT values
Sponsors:   University of Modena and Reggio Emilia;   Agenzia Italiana del Farmaco
Completed
Tue, 18 May 2010 12:00:00 EDT

Intravenous Versus Intravenous/Oral Antibiotics for Perforated Appendicitis

Condition:   Perforated Appendicitis
Interventions:   Drug: 5 days of IV antibiotics (ceftriaxone and metronidazole);   Drug: Home with oral antibiotics when eating (ampicillin/clavulanic acid)
Sponsor:   Children's Mercy Hospital Kansas City
Completed
Wed, 18 Apr 2007 12:00:00 EDT

The Use Of Pontic Shield Technique For Alveolar Ridge Preservation . A Case Series

Condition:   To Assess Bucco-lingual Dimension of the Ridge While Using Pontic Shield Technique as a Treatment Modality for Ridge Preservation
Intervention:   Procedure: Pontic Shield Technique
Sponsor:   Cairo University
Enrolling by invitation
Mon, 28 Sep 2020 12:00:00 EDT

Prophylaxis of Surgical Wound Infection With Topical Antibiotics

Conditions:   Surgical Site Infection;   Surgery--Complications;   Colorectal Surgery;   Cesarean Section; Infection;   Hernia, Abdominal
Intervention:   Other: Topical antibiotic prophylaxis
Sponsor:   Hospital de Granollers
Recruiting
Mon, 20 Jul 2020 12:00:00 EDT

Antibiotics for the Treatment of Ulcerative Colitis

Condition:   Colitis, Ulcerative
Interventions:   Drug: Cefuroxime;   Drug: Ciprofloxacin;   Drug: Clarithromycin;   Drug: Cotrimoxazole;   Drug: Coamoxiclav;   Drug: metronidazole;   Drug: neomycin;   Drug: rifaximin;   Drug: Vancomycin;   Drug: Doxycycline
Sponsors:   University of Dundee;   Tenovus Scotland
Completed
Mon, 24 Jul 2006 12:00:00 EDT

The Role of Antibiotic Treatment in Patients With Acute Mild Cholecystitis - A Prospective Randomized Controlled Trial

Condition:   Acute Cholecystitits
Interventions:   Drug: Antibiotic treatment;   Drug: No antibiotics
Sponsor:   Hadassah Medical Organization
Completed
Wed, 14 Nov 2007 12:00:00 EST

Effect of Topical Sinonasal Antibiotics

Conditions:   Chronic Rhinosinusitis (Diagnosis);   Antibiotic Side Effect
Intervention:   Drug: Oral versus topical antibioitics
Sponsor:   United States Naval Medical Center, San Diego
Unknown status
Thu, 02 May 2019 12:00:00 EDT

An Exploratory Study of TMC207 in Japanese Participants With Pulmonary Multi-Drug Resistant Tuberculosis (MDR-TB)

Condition:   Tuberculosis, Multidrug-Resistant
Interventions:   Drug: TMC207 (bedaquiline);   Drug: Background Regimen (BR)
Sponsor:   Janssen Pharmaceutical K.K.
Completed
Thu, 19 Feb 2015 12:00:00 EST

Population Pharmacokinetics of Anti-tuberculosis Drugs in Children With Tuberculosis

Condition:   Tuberculosis
Intervention:   Drug: anti-tuberculosis drug
Sponsors:   Beijing Children's Hospital;   Shandong University;   Robert Debré Hospital;   Rennes University Hospital
Recruiting
Fri, 10 Aug 2018 12:00:00 EDT

Antibiotic Dosing in Patients on Intermittent Hemodialysis

Conditions:   Kidney Failure, Chronic;   Antibiotics;   Hemodialysis
Intervention:   Other: Blood and urine sampling
Sponsors:   University Hospital, Ghent;   University Ghent
Recruiting
Wed, 10 Apr 2019 12:00:00 EDT

Vertical Augmentation Using Onlay Versus Inlay Autogenous Graft With Simultaneous Implant Placement.

Condition:   Bone Resorption
Intervention:   Other: assigned intervention
Sponsor:   Cairo University
Unknown status
Tue, 14 Feb 2017 12:00:00 EST

Non-operative Management for Appendicitis in Children

Conditions:   Acute Focal Appendicitis;   Appendicitis
Interventions:   Drug: Non-operative management group (NOM);   Procedure: Appendectomy group (Operative management, OM)
Sponsor:   Sydney Children's Hospitals Network
Unknown status
Fri, 10 Jun 2016 12:00:00 EDT

Comparing Healthcare Utilization Between Adenotonsillectomy Patients With and Without Postoperative Antibiotic Use

Conditions:   Snoring;   Strep Throat
Intervention:   Drug: Antibiotic
Sponsor:   University of Missouri-Columbia
Completed
Fri, 23 Mar 2012 12:00:00 EDT

Role of Antibiotics Post Tonsillectomy

Condition:   Tonsillectomy
Intervention:   Drug: Amoxicillin/clavulanate
Sponsor:   Assiut University
Unknown status
Mon, 09 Apr 2018 12:00:00 EDT

Effect of Amoxicillin/Clavulanic Acid Combination on Postoperative Endodontic Pain

Condition:   Symptomatic Periapical Periodontitis
Interventions:   Drug: Amoxicillin/Clavulanate Potassium 875 mg-125 mg oral tablet;   Drug: Placebo
Sponsor:   Cairo University
Unknown status
Mon, 02 Jan 2017 12:00:00 EST

Clinical Trial of the Treatment of Acute Sinusitis With Standard-dose Versus High-dose Amoxicillin/Clavulanate

Condition:   Sinusitis
Interventions:   Drug: standard dose amoxicillin/clavulanate;   Drug: high dose amoxicillin/clavulanate
Sponsor:   Albany Medical College
Completed
Fri, 16 Jan 2015 12:00:00 EST

The Impact of Antibiotic Prophylaxis on Incidence of Post-bronchoscopy Fever and Change of Serum Cytokines

Conditions:   Fever;   Pneumonia
Interventions:   Drug: oral amoxicillin/clavulanate 1g (875/125mg);   Drug: control
Sponsor:   Seoul National University Hospital
Completed
Thu, 18 Mar 2010 12:00:00 EDT

Antibiotic Therapy Versus Appendectomy for Acute Appendicitis

Condition:   Appendicitis
Interventions:   Drug: amoxicillin/clavulanate potassium;   Procedure: appendectomy
Sponsor:   Assistance Publique - Hôpitaux de Paris
Completed
Fri, 26 Aug 2005 12:00:00 EDT

Community-Acquired Pneumonia - Study on the Initial Treatment With Antibiotics of Lower Respiratory Tract Infections

Condition:   Community-acquired Pneumonia
Intervention:   Other: Preferred empirical treatment
Sponsors:   UMC Utrecht;   ZonMw: The Netherlands Organisation for Health Research and Development
Completed
Wed, 08 Aug 2012 12:00:00 EDT

Efficacy of Oxybutynin in Paediatric Cystitis

Condition:   Cystitis
Interventions:   Drug: Oxybutynin;   Other: "Orasweet" Liquid Placebo;   Drug: Antibiotics
Sponsor:   University of Calgary
Completed
Fri, 15 Mar 2019 12:00:00 EDT

Azithromycin+Amoxicillin/Clavulanate vs Amoxicillin/Clavulanate in COVID19 Patients With Pneumonia in Non-intensive Unit

Condition:   COVID-19 Pneumonia
Interventions:   Combination Product: Azithromycin with amoxicillin/clavulanate;   Drug: amoxicillin/clavulanate
Sponsor:   Nantes University Hospital
Not yet recruiting
Mon, 27 Apr 2020 12:00:00 EDT

Pharmacokinetics and Pleural Fluid Penetration of Amoxicillin and Clavulanic Acid in Patients With Pleural Infections

Conditions:   Pleural Infection;   Empyema;   Community-acquired Pneumonia;   Pharmacokinetic;   Amoxicillin
Interventions:   Procedure: chest tube drainage;   Biological: antibiotic concentration in pleural fluid;   Drug: Amoxicillin + clavulanic acid
Sponsor:   Centre Hospitalier Universitaire, Amiens
Recruiting
Fri, 17 Apr 2020 12:00:00 EDT

Systemic Steroids Plus Antibiotics in Sleep Apnea Syndrome in Children

Condition:   Obstructive Sleep Apnea Syndrome
Intervention:   Drug: Prednisolone and amoxicillin/clavulanate
Sponsor:   University of Chicago
Terminated
Wed, 04 Apr 2007 12:00:00 EDT

Comparison Study Between Cefdinir & Amoxicilline/Clavulanate in Acute Sinusitis and Assessment of Quality of Life

Condition:   Acute Bacterial Sinusitis
Interventions:   Drug: Cefdinir (drug);   Drug: amoxicillin/clavulanate
Sponsor:   University of Chicago
Completed
Wed, 07 Sep 2005 12:00:00 EDT

Best Treatment Choice for Osteonecrosis of the Jaw

Condition:   Medication Related Osteonecrosis of the Jaw
Interventions:   Drug: Antibiotics;   Drug: Chlorhexidine mouthwash;   Procedure: Minimally invasive surgery with LPRF;   Procedure: Surgical resection
Sponsors:   Tim Van den Wyngaert;   Kom Op Tegen Kanker
Not yet recruiting
Thu, 13 Aug 2020 12:00:00 EDT

Neonatal and Paediatric Pharmacokinetics of Antimicrobials Study

Condition:   Paediatric Antimicrobial Pharmacokinetics
Intervention:  
Sponsor:   St George's, University of London
Unknown status
Sun, 03 Nov 2013 12:00:00 EDT

A Safety and Tolerability Study of Doripenem Compared With Cefepime in Hospitalized Children With Bacterial Pneumonia

Conditions:   Pneumonia, Bacterial;   Community-Acquired Infections;   Nosocomial Infection;   Pneumonia, Ventilator-Associated
Interventions:   Drug: Cefepime placebo;   Drug: Cefepime;   Drug: Doripenem;   Drug: Doripenem placebo;   Drug: Amoxicillin/clavulanate potassium
Sponsor:   Janssen Research & Development, LLC
Terminated
Mon, 26 Apr 2010 12:00:00 EDT

A Safety and Tolerability Study of Doripenem Compared With Cefepime in Children Hospitalized With Complicated Urinary Tract Infections

Condition:   Complicated Urinary Tract Infections or Pyelonephritis
Interventions:   Drug: Doripenem;   Drug: Doripenem placebo;   Drug: Cefepime;   Drug: Cefepime placebo;   Drug: Amoxicillin/clavulanate potassium
Sponsor:   Janssen Research & Development, LLC
Terminated
Mon, 26 Apr 2010 12:00:00 EDT

A Safety and Tolerability Study of Doripenem Compared With Meropenem in Children Hospitalized With Complicated Intra-abdominal Infections

Conditions:   Abscess, Intra-Abdominal;   Abdominal Abscess;   Abdomen, Acute;   Abdominal Pain;   Appendicitis;   Rupture;   Infection;   Intestinal Perforation;   Peritonitis;   Ileus
Interventions:   Drug: Doripenem;   Drug: Meropenem placebo;   Drug: Meropenem;   Drug: Doripenem placebo;   Drug: Amoxicillin/clavulanate potassium
Sponsor:   Janssen Research & Development, LLC
Terminated
Mon, 26 Apr 2010 12:00:00 EDT

Study to Evaluate the Efficacy and Safety of Moxifloxacin Versus Amoxicillin/Clavulanate in the Treatment of Acute Bacterial Rhinosinusitis

Conditions:   Sinusitis;   Bacterial Infections
Interventions:   Drug: Moxifloxacin (Avelox, BAY12-8039);   Drug: Amoxicillin/Clavulanate
Sponsor:   Bayer
Terminated
Wed, 27 Jun 2007 12:00:00 EDT

Comparison The Postoperative Effects of Local and Systemic Antibiotics Applied With Platelets Rich Fibrin

Condition:   Impacted Wisdom Tooth
Interventions:   Diagnostic Test: Diagnosis;   Procedure: traditional osteotomies;   Biological: Platelet Rich Fibrin;   Drug: Antibiotics, Penicillin;   Drug: Analgesic;   Drug: Antibiotic
Sponsor:   Ceren Melahat Donmezer
Completed
Wed, 04 Aug 2021 12:00:00 EDT

Levofloxacin In The Treatment Of Children With Recurrent And/or Persistent Acute Otitis Media

Condition:   Otitis Media
Intervention:   Drug: levofloxacin; amoxicillin/clavulanate
Sponsor:   Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Completed
Fri, 17 Jan 2003 12:00:00 EST

Beta-Lactams Dosing In Pneumonia in ICU in Patients Treated by Continuous Renal Replacement Therapy: the BLIPIC Study

Conditions:   Beta-lactam;   Continuous Renal Replacement Therapy;   Pneumonia;   Antibiotic
Intervention:  
Sponsors:   Centre Hospitalier de Valenciennes;   Centre Hospitalier de Lens;   Centre Hospitalier de Bethune;   University Hospital, Lille;   General Hospital of Douai;   Centre hospitalier de Boulogne
Recruiting
Mon, 01 Apr 2019 12:00:00 EDT

Risk of Acute Liver Injury in Users of Antimicrobials

Condition:   Drug-Induced Liver Injury
Interventions:   Drug: Moxifloxacin (Avelox, BAY12-8039);   Drug: Amoxicillin, Amoxicillin plus clavulanic acid, Cefuroxime, Clarithromycin, Doxycycline, Levofloxacin, Telithromycin
Sponsors:   Bayer;   RTI Health Solutions
Completed
Wed, 14 Sep 2011 12:00:00 EDT

Perianal Abscess Recurrence and Fistula Formation: Antibiotics Following Incision and Drainage Trial

Conditions:   Perianal Abscess;   Perianal Fistula
Interventions:   Drug: Antibiotic 1 arm (amoxicillin + clavulanic acid);   Drug: Antibiotic 2 arm (ciprofloxacin + metronidazole)
Sponsor:   Sunnybrook Health Sciences Centre
Not yet recruiting
Wed, 16 Sep 2020 12:00:00 EDT

Study on Reduced Antibiotic Treatment vs Broad Spectrum Betalactam in Patients With Bacteremia by Enterobacteriaceae

Condition:   Enterobacteriaceae Infections
Interventions:   Drug: Antipseudomonal beta-lactam antibiotic;   Drug: De-escalation(short-spectrum antibiotic)
Sponsors:   Fundación Pública Andaluza para la gestión de la Investigación en Sevilla;   Spanish Network for Research in Infectious Diseases
Completed
Fri, 10 Jun 2016 12:00:00 EDT

Moxifloxacin in Pediatric Subjects With Complicated Intra-abdominal Infection

Condition:   Intraabdominal Infections
Interventions:   Drug: Moxifloxacin (Avelox, BAY12-8039);   Drug: Ertapenem;   Drug: Amoxicillin/Clavulanate;   Drug: Moxifloxacin placebo;   Drug: Ertapenem placebo;   Drug: Amoxicillin/Clavulanate placebo
Sponsor:   Bayer
Completed
Wed, 17 Feb 2010 12:00:00 EST

A Study to Assess the Efficacy and Safety of IV/PO Moxifloxacin in Subjects With Community-acquired Pneumonia

Condition:   Pneumonia
Interventions:   Drug: Avelox (Moxifloxacin, BAY12-8039);   Drug: Ceftriaxone; Azithromycin; Amoxicilline/clavulanate; Clarithromycin
Sponsor:   Bayer
Completed
Thu, 17 Jul 2008 12:00:00 EDT

A Study of the Effectiveness and Safety of High Dose, Short-course Levofloxacin in the Treatment of Acute Bacterial Exacerbation (Worsening) of Chronic Bronchitis.

Conditions:   Bronchitis;   Chronic Bronchitis
Intervention:   Drug: levofloxacin, azithromycin, amoxicillin/clavulanate
Sponsors:   Johnson & Johnson Pharmaceutical Research & Development, L.L.C.;   PriCara, Unit of Ortho-McNeil, Inc.
Completed
Wed, 07 Aug 2002 12:00:00 EDT