Full text biomedical articles

Anastrozole Aromatase Inhibitor Plasma Drug Concentration Genome‐Wide Association Study: Functional Epistatic Interaction Between SLC38A7 and ALPPL2

Tanda M. Dudenkov, Duan Liu, Junmei Cairns, Sandhya Devarajan, Yongxian Zhuang, James N. Ingle, Aman U. Buzdar, Mark E. Robson, Michiaki Kubo, Anthony Batzler, Poulami Barman, Gregory D. Jenkins, Erin E. Carlson, Matthew P. Goetz, Donald W. Northfelt, Alvaro Moreno‐Aspitia, Zeruesenay Desta, Joel M. Reid, Krishna R. Kalari, Liewei Wang, Richard M. Weinshilboum
Clin Pharmacol Ther. 2019 Jul; 106(1): 219–227. Published online 2019 Mar 18. doi: 10.1002/cpt.1359


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Effects of psoralen on the pharmacokinetics of anastrozole in rats

Yuzhu Zhang, Jingjing Wu, Yue Zhou, Yulian Yin, Hongfeng Chen
Pharm Biol. 2018; 56(1): 433–439. Published online 2018 Oct 21. doi: 10.1080/13880209.2018.1501584


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Pharmacokinetic evaluation of a transdermal anastrozole-in-adhesive formulation

Ralf Regenthal, Margarita Voskanian, Frank Baumann, Jens Teichert, Christian Brätter, Achim Aigner, Getu Abraham
Drug Des Devel Ther. 2018; 12: 3653–3664. Published online 2018 Nov 1. doi: 10.2147/DDDT.S170764


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Estrogens and their precursors in postmenopausal women with early breast cancer receiving anastrozole

James N. Ingle, KR Kalari, Aman U. Buzdar, Mark E. Robson, Matthew P. Goetz, Zeruesenay Desta, Poulami Barman, Tanda T. Dudenkov, Donald W. Northfelt, Edith A. Perez, David A. Flockhart, Clark V. Williard, Liewei Wang, Richard M. Weinshilboum
Steroids. Author manuscript; available in PMC 2016 Jul 1.
Published in final edited form as: Steroids. 2015 Jul; 99(0 0): 32–38. Published online 2014 Aug 24. doi: 10.1016/j.steroids.2014.08.007


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Fulvestrant decreases anastrozole drug concentrations when taken concurrently by patients with metastatic breast cancer treated on SWOG study S0226

Daniel L. Hertz, William E. Barlow, Kelley M. Kidwell, Kathy S. Albain, Ted A. Vandenberg, Shaker R. Dakhil, Nagendra R. Tirumali, Robert B. Livingston, Julie Gralow, Daniel F. Hayes, Gabriel N. Hortobagyi, Rita S. Mehta, James M. Rae
Br J Clin Pharmacol. 2016 Jun; 81(6): 1134–1141. Published online 2016 Apr 8. doi: 10.1111/bcp.12904


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A meta-analysis of randomized controlled trials comparing the efficacy and safety of anastrozole versus tamoxifen for breast cancer

Yan Yang, Wei Pan, Xinyu Tang, Shuqing Wu, Xinchen Sun
Oncotarget. 2017 Jul 18; 8(29): 48362–48374. Published online 2017 Mar 22. doi: 10.18632/oncotarget.16466


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Vitamin D Compounds PRI-2191 and PRI-2205 Enhance Anastrozole Activity in Human Breast Cancer Models

Beata Filip-Psurska, Mateusz Psurski, Artur Anisiewicz, Patrycja Libako, Ewa Zbrojewicz, Magdalena Maciejewska, Michał Chodyński, Andrzej Kutner, Joanna Wietrzyk
Int J Mol Sci. 2021 Mar; 22(5): 2781. Published online 2021 Mar 9. doi: 10.3390/ijms22052781


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Potent Cell-Cycle Inhibition and Upregulation of Immune Response with Abemaciclib and Anastrozole in neoMONARCH, Phase II Neoadjuvant Study in HR+/HER2− Breast Cancer

Sara A. Hurvitz, Miguel Martin, Michael F. Press, David Chan, María Fernandez-Abad, Edgar Petru, Regan Rostorfer, Valentina Guarneri, Chiun-Sheng Huang, Susana Barriga, Sameera Wijayawardana, Manisha Brahmachary, Philip J. Ebert, Anwar Hossain, Jiangang Liu, Adam Abel, Amit Aggarwal, Valerie M. Jansen, Dennis J. Slamon
Clin Cancer Res. Author manuscript; available in PMC 2020 Sep 17.
Published in final edited form as: Clin Cancer Res. 2020 Feb 1; 26(3): 566–580. Published online 2019 Oct 15. doi: 10.1158/1078-0432.CCR-19-1425


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Polymorphisms in ABCB1 and CYP19A1 genes affect anastrozole plasma concentrations and clinical outcomes in postmenopausal breast cancer patients

Guillermo Gervasini, Carlos Jara, Clara Olier, Nuria Romero, Ruth Martínez, Juan Antonio Carrillo
Br J Clin Pharmacol. 2017 Mar; 83(3): 562–571. Published online 2016 Oct 18. doi: 10.1111/bcp.13130


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Overall Survival with Fulvestrant plus Anastrozole in Metastatic Breast Cancer

Rita S. Mehta, William E. Barlow, Kathy S. Albain, Ted A. Vandenberg, Shaker R. Dakhil, Nagendra R. Tirumali, Danika L. Lew, Daniel F. Hayes, Julie R. Gralow, Hannah M. Linden, Robert B. Livingston, Gabriel N. Hortobagyi
N Engl J Med. Author manuscript; available in PMC 2019 Dec 1.
Published in final edited form as: N Engl J Med. 2019 Mar 28; 380(13): 1226–1234. doi: 10.1056/NEJMoa1811714


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Comparison of risedronate versus placebo in preventing anastrozole-induced bone loss in women at high risk of developing breast cancer with osteopenia

Ivana Sestak, Glen M. Blake, Rajesh Patel, Robert E. Coleman, Jack Cuzick, Richard Eastell
Bone. 2019 Jul; 124: 83–88. doi: 10.1016/j.bone.2019.04.016


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Differences between the non-steroidal aromatase inhibitors anastrozole and letrozole – of clinical importance?

J Geisler
Br J Cancer. 2011 Mar 29; 104(7): 1059–1066. Published online 2011 Mar 1. doi: 10.1038/bjc.2011.58


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Anastrozole and levonorgrestrel-releasing intrauterine device in the treatment of endometriosis: a randomized clinical trial

Pedro Acién, Irene Velasco, Maribel Acién
BMC Womens Health. 2021; 21: 211. Published online 2021 May 20. doi: 10.1186/s12905-021-01347-9


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Cost-effectiveness analysis of anastrozole vs tamoxifen in adjuvant therapy for early stage breast cancer in the United Kingdom: the 5-year completed treatment analysis of the ATAC (‘Arimidex', Tamoxifen alone or in combination) trial

R Mansel, G Locker, L Fallowfield, Á Benedict, D Jones
Br J Cancer. 2007 Jul 16; 97(2): 152–161. Published online 2007 Jul 10. doi: 10.1038/sj.bjc.6603804


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Cytotoxicity anticancer activities of anastrozole against breast, liver hepatocellular, and prostate cancer cells

Firas Hassan, Gamal A. El-Hiti, Mays Abd-Allateef, Emad Yousif
Saudi Med J. 2017 Apr; 38(4): 359–365. doi: 10.15537/smj.2017.4.17061


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A prospective, randomized study on hepatotoxicity of anastrozole compared with tamoxifen in women with breast cancer

Ying Lin, Jianlun Liu, Xiaohua Zhang, Li Li, Rui Hu, Jian Liu, Yongchuan Deng, Dedian Chen, Yangbing Zhao, Shengrong Sun, Rong Ma, Ying Zhao, Jinping Liu, Yang Zhang, Xijing Wang, Yafen Li, Pingqing He, Enxiao Li, Zheli Xu, Yaqun Wu, Zhongsheng Tong, Xiaojia Wang, Tao Huang, Zhongxiao Liang, Shui Wang, Fengxi Su, Yunfei Lu, Helong Zhang, Guosheng Feng, Shenming Wang
Cancer Sci. 2014 Sep; 105(9): 1182–1188. Published online 2014 Sep 18. doi: 10.1111/cas.12474


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In vitro and in vivo oxidative metabolism and glucuronidation of anastrozole

Landry K Kamdem, Yong Liu, Vered Stearns, Susan A Kadlubar, Jacqueline Ramirez, Stacie Jeter, Karineh Shahverdi, Bryan A Ward, Evan Ogburn, Mark J Ratain, David A Flockhart, Zeruesenay Desta
Br J Clin Pharmacol. 2010 Dec; 70(6): 854–869. doi: 10.1111/j.1365-2125.2010.03791.x


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Antiplatelet Therapy Combined with Anastrozole Induces Features of Partial EMT in Breast Cancer Cells and Fails to Mitigate Breast-Cancer Induced Hypercoagulation

Kutlwano R. Xulu, Tanya N. Augustine
Int J Mol Sci. 2021 Apr; 22(8): 4153. Published online 2021 Apr 16. doi: 10.3390/ijms22084153


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Anastrozole versus tamoxifen for the prevention of locoregional and contralateral breast cancer in postmenopausal women with locally excised ductal carcinoma in situ (IBIS-II DCIS): a double-blind, randomised controlled trial

John F Forbes, Ivana Sestak, Anthony Howell, Bernardo Bonanni, Nigel Bundred, Christelle Levy, Gunter von Minckwitz, Wolfgang Eiermann, Patrick Neven, Michael Stierer, Chris Holcombe, Robert E Coleman, Louise Jones, Ian Ellis, Jack Cuzick, IBIS-II investigators
Lancet. 2016 Feb 27; 387(10021): 866–873. doi: 10.1016/S0140-6736(15)01129-0


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Clinical and genomic analysis of a randomised phase II study evaluating anastrozole and fulvestrant in postmenopausal patients treated for large operable or locally advanced hormone-receptor-positive breast cancer

Nathalie Quenel-Tueux, Marc Debled, Justine Rudewicz, Gaetan MacGrogan, Marina Pulido, Louis Mauriac, Florence Dalenc, Thomas Bachelot, Barbara Lortal, Christelle Breton-Callu, Nicolas Madranges, Christine Tunon de Lara, Marion Fournier, Hervé Bonnefoi, Hayssam Soueidan, Macha Nikolski, Audrey Gros, Catherine Daly, Henry Wood, Pamela Rabbitts, Richard Iggo
Br J Cancer. 2015 Aug 11; 113(4): 585–594. Published online 2015 Jul 14. doi: 10.1038/bjc.2015.247


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