Full text biomedical articles

Old Things New View: Ascorbic Acid Protects the Brain in Neurodegenerative Disorders

Adriana Covarrubias-Pinto, Aníbal Ignacio Acuña, Felipe Andrés Beltrán, Leandro Torres-Díaz, Maite Aintzane Castro
Int J Mol Sci. 2015 Dec; 16(12): 28194–28217. Published online 2015 Nov 27. doi: 10.3390/ijms161226095


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In vivo fluorescence bioimaging of ascorbic acid in mice: Development of an efficient probe consisting of phthalocyanine, TEMPO, and albumin

Takanori Yokoi, Takayuki Otani, Kazuyuki Ishii
Sci Rep. 2018; 8: 1560. Published online 2018 Jan 24. doi: 10.1038/s41598-018-19762-8


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Ascorbic acid for the treatment of Charcot‐Marie‐Tooth disease

Burkhard Gess, Jonathan Baets, Peter De Jonghe, Mary M Reilly, Davide Pareyson, Peter Young
Cochrane Database Syst Rev. 2015 Dec; 2015(12): CD011952. Published online 2015 Dec 11. doi: 10.1002/14651858.CD011952


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Ascorbic Acid Mitigates D-galactose-Induced Brain Aging by Increasing Hippocampal Neurogenesis and Improving Memory Function

Sung Min Nam, Misun Seo, Jin-Seok Seo, Hyewhon Rhim, Sang-Soep Nahm, Ik-Hyun Cho, Byung-Joon Chang, Hyeon-Joong Kim, Sun-Hye Choi, Seung-Yeol Nah
Nutrients. 2019 Jan; 11(1): 176. Published online 2019 Jan 15. doi: 10.3390/nu11010176


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Plasma ascorbic acid and the risk of islet autoimmunity and type 1 diabetes: the TEDDY study

Markus Mattila, Iris Erlund, Hye-Seung Lee, Sari Niinistö, Ulla Uusitalo, Carin Andrén Aronsson, Sandra Hummel, Hemang Parikh, Stephen S. Rich, William Hagopian, Jorma Toppari, Åke Lernmark, Anette G. Ziegler, Marian Rewers, Jeffrey P. Krischer, Jill M. Norris, Suvi M. Virtanen, for the TEDDY Study Group
Diabetologia. 2020; 63(2): 278–286. Published online 2019 Nov 14. doi: 10.1007/s00125-019-05028-z


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Glucose transporter 10 modulates adipogenesis via an ascorbic acid-mediated pathway to protect mice against diet-induced metabolic dysregulation

Chung-Lin Jiang, Wei-Ping Jen, Chang-Yu Tsao, Li-Ching Chang, Chien-Hsiun Chen, Yi-Ching Lee
PLoS Genet. 2020 May; 16(5): e1008823. Published online 2020 May 26. doi: 10.1371/journal.pgen.1008823


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Treatment of Irradiated Mice with High-Dose Ascorbic Acid Reduced Lethality

Tomohito Sato, Manabu Kinoshita, Tetsuo Yamamoto, Masataka Ito, Takafumi Nishida, Masaru Takeuchi, Daizoh Saitoh, Shuhji Seki, Yasuo Mukai
PLoS One. 2015; 10(2): e0117020. Published online 2015 Feb 4. doi: 10.1371/journal.pone.0117020


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Phase I safety trial of intravenous ascorbic acid in patients with severe sepsis

Alpha A Fowler, III, Aamer A Syed, Shelley Knowlson, Robin Sculthorpe, Don Farthing, Christine DeWilde, Christine A Farthing, Terri L Larus, Erika Martin, Donald F Brophy, Seema Gupta, Bernard J Fisher, Ramesh Natarajan
J Transl Med. 2014; 12: 32. Published online 2014 Jan 31. doi: 10.1186/1479-5876-12-32


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Protective effects of ascorbic acid and calcitriol combination on airway remodelling in ovalbumin-induced chronic asthma

Farzaneh Kianian, Seyed Morteza Karimian, Mehri Kadkhodaee, Nasrin Takzaree, Behjat Seifi, Hamid Reza Sadeghipour
Pharm Biol. 2020; 58(1): 107–115. Published online 2020 Jan 16. doi: 10.1080/13880209.2019.1710218


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Redox Interactions of Vitamin C and Iron: Inhibition of the Pro-Oxidant Activity by Deferiprone

Viktor A. Timoshnikov, Tatyana V. Kobzeva, Nikolay E. Polyakov, George J. Kontoghiorghes
Int J Mol Sci. 2020 Jun; 21(11): 3967. Published online 2020 May 31. doi: 10.3390/ijms21113967


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Preventive and therapeutic potential of ascorbic acid in neurodegenerative diseases

Morgana Moretti, Daiane Bittencourt Fraga, Ana Lúcia S. Rodrigues
CNS Neurosci Ther. 2017 Dec; 23(12): 921–929. Published online 2017 Oct 4. doi: 10.1111/cns.12767


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Near-Infrared Spectroscopy and Aquaphotomics for Monitoring Mung Bean (Vigna radiata) Sprout Growth and Validation of Ascorbic Acid Content

David Tjandra Nugraha, John-Lewis Zinia Zaukuu, Juan Pablo Aguinaga Bósquez, Zsanett Bodor, Flora Vitalis, Zoltan Kovacs
Sensors (Basel) 2021 Jan; 21(2): 611. Published online 2021 Jan 17. doi: 10.3390/s21020611


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Topical Ascorbic Acid Ameliorates Oxidative Stress-Induced Corneal Endothelial Damage via Suppression of Apoptosis and Autophagic Flux Blockage

Yi-Jen Hsueh, Yaa-Jyuhn James Meir, Lung-Kun Yeh, Tze-Kai Wang, Chieh-Cheng Huang, Tsai-Te Lu, Chao-Min Cheng, Wei-Chi Wu, Hung-Chi Chen
Cells. 2020 Apr; 9(4): 943. Published online 2020 Apr 11. doi: 10.3390/cells9040943


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Comparison of protective effect of ascorbic acid on redox and endocannabinoid systems interactions in in vitro cultured human skin fibroblasts exposed to UV radiation and hydrogen peroxide

Agnieszka Gęgotek, Katarzyna Bielawska, Michał Biernacki, Ilona Zaręba, Arkadiusz Surażyński, Elżbieta Skrzydlewska
Arch Dermatol Res. 2017; 309(4): 285–303. Published online 2017 Mar 11. doi: 10.1007/s00403-017-1729-0


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Ascorbic acid stimulates the in vitro myoblast proliferation and migration of pacu (Piaractus mesopotamicus)

Bruno Oliveira Silva Duran, Guilherme Alcarás Góes, Bruna Tereza Thomazini Zanella, Paula Paccielli Freire, Jessica Silvino Valente, Rondinelle Artur Simões Salomão, Ana Fernandes, Edson Assunção Mareco, Robson Francisco Carvalho, Maeli Dal-Pai-Silva
Sci Rep. 2019; 9: 2229. Published online 2019 Feb 18. doi: 10.1038/s41598-019-38536-4


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Ascorbic Acid Inhibition of Candida albicans Hsp90-Mediated Morphogenesis Occurs via the Transcriptional Regulator Upc2

Frédérique Van Hauwenhuyse, Alessandro Fiori, Patrick Van Dijck
Eukaryot Cell. 2014 Oct; 13(10): 1278–1289. doi: 10.1128/EC.00096-14


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Oral ascorbic acid 2-glucoside prevents coordination disorder induced via laser-induced shock waves in rat brain

Takaaki Maekawa, Takahiro Uchida, Yuka Nakata-Horiuchi, Hiroaki Kobayashi, Satoko Kawauchi, Manabu Kinoshita, Daizoh Saitoh, Shunichi Sato
PLoS One. 2020; 15(4): e0230774. Published online 2020 Apr 2. doi: 10.1371/journal.pone.0230774


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Adipogenic and Lipolytic Effects of Ascorbic Acid in Ovariectomized Rats

Byoungjae Kim, Kyung Min Choi, Hong Soon Yim, Hyun Tae Park, Joung Han Yim, Min-Goo Lee
Yonsei Med J. 2018 Jan 1; 59(1): 85–91. Published online 2017 Nov 29. doi: 10.3349/ymj.2018.59.1.85


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Application of Transgalactosylation Activity of β-Galactosidase from Kluyveromyces lactis for the Synthesis of Ascorbic Acid Galactoside

Aleksandra Wojciechowska, Robert Klewicki, Michał Sójka, Katarzyna Grzelak-Błaszczyk
Appl Biochem Biotechnol. 2018; 184(1): 386–400. Published online 2017 Jul 13. doi: 10.1007/s12010-017-2551-z


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Ascorbic Acid Promotes the Stemness of Corneal Epithelial Stem/Progenitor Cells and Accelerates Epithelial Wound Healing in the Cornea

Jialin Chen, Jie Lan, Dongle Liu, Ludvig J. Backman, Wei Zhang, Qingjun Zhou, Patrik Danielson
Stem Cells Transl Med. 2017 May; 6(5): 1356–1365. Published online 2017 Mar 9. doi: 10.1002/sctm.16-0441


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