Clinical Trials

Intravenous (IV) Vitamin C With Chemotherapy for Cisplatin Ineligible Bladder Cancer Patients

Condition:   Bladder Cancer
Intervention:   Drug: Ascorbic Acid
Sponsor:   University of Kansas Medical Center
Recruiting

Tue, 06 Aug 2019 12:00:00 EDT

Pharmacologic Ascorbic Acid as an Activator of Lymphocyte Signaling for COVID-19 Treatment

Condition:   COVID-19
Intervention:   Drug: Ascorbic Acid
Sponsor:   Thomas Jefferson University
Not yet recruiting

Mon, 27 Apr 2020 12:00:00 EDT

Vitamin C in Cardiac Surgery Patients

Condition:   Coronary Artery Bypass Graft Surgery
Intervention:   Drug: Ascorbic Acid
Sponsors:   Geisinger Clinic;   Wilkes University
Completed

Fri, 21 Apr 2017 12:00:00 EDT

Perioperative Vitamin C Lung Transplant

Conditions:   Primary Graft Dysfunction;   Lung Transplant; Complications
Intervention:   Drug: Vitamin C
Sponsor:   University of Wisconsin, Madison
Not yet recruiting

Mon, 10 Aug 2020 12:00:00 EDT

Impact of Ascorbic Acid in the Prevention of Vancomycin Induced Nephrotoxicty

Condition:   Acute Kidney Injury
Intervention:   Drug: Ascorbic Acid
Sponsor:   Ain Shams University
Recruiting

Fri, 19 Apr 2019 12:00:00 EDT

Intravenous Ascorbic Acid Administration in Hysterectomy

Condition:   Abdominal Hysterectomy
Intervention:   Drug: vitamin C
Sponsor:   Shahid Beheshti University
Completed

Wed, 29 May 2019 12:00:00 EDT

Effect of Low Doses of Vitamin C on Salivary Cortisol , Heart Rate , Blood Pressure During Group Presentation

Condition:   Stress, Psychological
Interventions:   Drug: ascorbic acid;   Other: placebo
Sponsor:   Kufa University
Completed

Tue, 22 Oct 2019 12:00:00 EDT

Determining the Safe Dosage of Ascorbic Acid Used in the Treatment of Occluded Totally Implanted Central Venous Catheter

Condition:   Occluded Totally Implanted Central Venous Catheter
Intervention:   Drug: Ascorbic Acid
Sponsor:   University of Sao Paulo
Completed

Wed, 05 Jan 2011 12:00:00 EST

Intravenous Ascorbic Acid in Women Receiving Adjuvant or Neo-Adjuvant Chemotherapy for Early Stage Breast Cancer

Condition:   Fatigue
Interventions:   Drug: Ascorbic Acid;   Other: Normal Saline
Sponsor:   Midwestern Regional Medical Center
Withdrawn

Thu, 13 Aug 2015 12:00:00 EDT

Effect of Ascorbic Acid Supplementation in Pregnancy on Anemia (AAA)

Condition:   Anemia in Pregnancy
Intervention:   Dietary Supplement: Vitamin C
Sponsors:   Fetal Medicine Foundation;   Wright State University;   Five Rivers Health Centers
Unknown status

Thu, 21 Jun 2018 12:00:00 EDT

Outcomes of Septic Shock Patients Treated With a Metabolic Resuscitation Bundle Consisting of Intravenous Hydrocortisone, Ascorbic Acid and Thiamine.

Conditions:   Septic Shock;   Ascorbic Acid Deficiency
Intervention:   Drug: Intravenous Ascorbic Acid
Sponsor:   University of Wisconsin, Madison
Completed

Fri, 12 Apr 2019 12:00:00 EDT

Vitamin C to Reduce Morning Cardiovascular Risk

Condition:   Cardiovascular Risk Factor
Interventions:   Dietary Supplement: Vitamin C;   Other: Placebo
Sponsor:   Oregon Health and Science University
Recruiting

Mon, 25 Sep 2017 12:00:00 EDT

Ascorbic Acid on Restenosis of Dysfunctional Hemodialysis Vascular Access

Condition:   Hemodialysis Access Failure
Interventions:   Drug: Ascorbic Acid 300 MG;   Drug: Ascorbic Acid 600 MG;   Drug: Normal saline
Sponsor:   National Taiwan University Hospital Hsin-Chu Branch
Completed

Tue, 15 May 2018 12:00:00 EDT

Lead Detoxifying Effects of Ascorbic Acid Among School Going Adolescents of Karachi- A Cluster Randomized Control Trial

Condition:   Elevated Blood Lead Levels
Intervention:   Drug: Ascorbic Acid
Sponsors:   Aga Khan University;   Pakistan Science Foundation
Completed

Wed, 20 Apr 2016 12:00:00 EDT

Ascorbic Acid Administration in the Treatment of Anemia in Chronic Hemodialysed Patients

Conditions:   Anaemia Response to the Treatment;   Peripheral Iron Indices;   Oxalemia
Intervention:   Drug: Ascorbic Acid
Sponsor:   Anemia Working Group Romania
Recruiting

Tue, 26 Aug 2014 12:00:00 EDT

Efficacy of Injectable Vitamin C on Accelerating Canine Movement: A Clinical Study

Condition:   Palatally Impacted Canines
Intervention:   Drug: vitamin C
Sponsor:   Cairo University
Completed

Thu, 24 Aug 2017 12:00:00 EDT

Effect of Ascorbic Acid on Postoperative Pulmonary Complications in Patients Undergoing Cardiac Surgery

Condition:   Postoperative Pulmonary Complications
Interventions:   Drug: Ascorbic Acid;   Drug: Saline
Sponsor:   Xuzhou Medical University
Unknown status

Wed, 28 Nov 2018 12:00:00 EST

Intravenous Ascorbic Acid Supplementation in Neoadjuvant Chemotherapy for Breast Cancer

Condition:   Breast Cancer
Interventions:   Drug: Ascorbic Acid;   Drug: Placebos
Sponsors:   Academic Emergency County Hospital Sibiu;   CHU-UCL Namur (site Mont-Godinne), Belgium
Unknown status

Mon, 05 Jun 2017 12:00:00 EDT

Study of High Dose Intravenous (IV) Ascorbic Acid in Measurable Solid Tumor Disease

Conditions:   Sarcoma;   Adenocarcinoma;   Carcinoma;   Multiple Myeloma;   Desmoplastic Small Round Cell Tumor
Intervention:   Drug: Ascorbic acid (vitamin C)
Sponsor:   Situs Cancer Research Center
Suspended

Tue, 18 May 2010 12:00:00 EDT

The Effect of High Dose Parenteral Ascorbic Acid On Microcirculation In Sepsis

Conditions:   Sepsis;   Septic Shock
Interventions:   Drug: Ascorbic acid;   Drug: Placebo
Sponsor:   Lithuanian University of Health Sciences
Completed

Fri, 26 Feb 2021 12:00:00 EST

Impact of Ascorbic Acid Treatment on the Development and Treatment of Vasodilation in Cardiac Surgery

Condition:   Vasoplegia
Intervention:   Drug: Ascorbic Acid
Sponsor:   Mayo Clinic
Completed

Fri, 16 Nov 2018 12:00:00 EST

Therapeutic Use of Intravenous Vitamin C in Allogeneic Stem Cell Transplant Recipients

Conditions:   Hodgkin Lymphoma;   Lymphoid Leukemia;   Multiple Myeloma;   Myeloid Leukemia;   Monocytic Leukemia;   Non Hodgkin Lymphoma;   Myelodysplasia
Intervention:   Drug: Intravenous (IV) and oral Vitamin C
Sponsor:   Virginia Commonwealth University
Recruiting

Fri, 03 Aug 2018 12:00:00 EDT

Administration of Intravenous Vitamin C in Novel Coronavirus Infection (COVID-19) and Decreased Oxygenation

Conditions:   COVID-19;   Hypoxia
Intervention:   Drug: L-ascorbic acid
Sponsors:   Hunter Holmes Mcguire Veteran Affairs Medical Center;   McGuire Research Institute
Completed

Wed, 22 Apr 2020 12:00:00 EDT

TET2 Mutations in Myelodysplastic Syndromes and Acute Myeloid Leukemia With Azacitidine + Ascorbic Acid

Conditions:   Myelodysplastic Syndromes;   Myeloproliferative Neoplasm;   Acute Myeloid Leukemia
Interventions:   Drug: Azacitidine;   Drug: Ascorbic acid
Sponsor:   Case Comprehensive Cancer Center
Completed

Thu, 11 Jan 2018 12:00:00 EST

Ascorbic Acid Treatment in Congenital Glucocorticoids and Mineralocorticoids Deficiency Due to NNT Mutation

Condition:   Glucocorticoids Deficiency
Intervention:   Drug: Ascorbic Acid
Sponsors:   Hadassah Medical Organization;   Soroka University Medical Center
Unknown status

Wed, 20 Jul 2016 12:00:00 EDT

Parenteral Ascorbic Acid Repletion in TransplantatIon

Condition:   Liver Transplant Failure and Rejection
Interventions:   Drug: Ascorbic acid;   Other: Placebo
Sponsor:   University of Wisconsin, Madison
Not yet recruiting

Tue, 16 Feb 2021 12:00:00 EST

Assessing the Efficacy and Safety of IV Vitamin C in Combination With Standard Chemotherapy for Pancreatic Ca

Condition:   Stage IV Pancreatic Cancer
Intervention:   Drug: Ascorbic Acid
Sponsor:   Thomas Jefferson University
Terminated

Thu, 15 Mar 2012 12:00:00 EDT

Vitamin C for the Prevention of UTI in Women Who Undergo Elective GYN Surgeries

Condition:   Catheter-Associated Urinary Tract Infection, Ascorbic Acid
Intervention:   Drug: Ascorbic Acid 1000 MG
Sponsor:   American University of Beirut Medical Center
Withdrawn

Fri, 11 Jan 2019 12:00:00 EST

Ascorbic Acid (Vitamin C) Infusion in Human Sepsis

Conditions:   Sepsis;   Septic Shock;   Hypotension;   Acute Lung Injury
Interventions:   Drug: Ascorbic Acid;   Drug: Placebo
Sponsor:   Virginia Commonwealth University
Completed

Wed, 14 Sep 2011 12:00:00 EDT

Efficacy of Vitamin C Administration for the Prevention of Postpolypectomy Bleeding

Condition:   Postpolypectomy Bleeding
Interventions:   Other: Ascorbic acid;   Other: Normal Saline
Sponsor:   Ilam University of Medical Sciences
Completed

Wed, 17 Jan 2018 12:00:00 EST

Influence of High Vitamin C Dose on Lactate During and After Extracorporeal Circulation

Conditions:   Hyperlactatemia;   Cardiac Disease;   Bypass Complication;   Valve Disease, Heart;   Vitamin C
Interventions:   Dietary Supplement: ascorbic acid,;   Other: Placebo (saline)
Sponsor:   University Medical Centre Maribor
Unknown status

Tue, 06 Aug 2019 12:00:00 EDT

A Pharmacokinetics Study of Intravenous Ascorbic Acid

Condition:   Pharmacokinetics
Intervention:   Drug: Ascor L 500® (Ascorbic Acid Injection, USP)
Sponsor:   McGuff Pharmaceuticals, Inc.
Completed

Fri, 28 Aug 2015 12:00:00 EDT

Ascorbic Acid Versus Diode Laser in the Treatment of Gingival Hyperpigmentation

Condition:   Gingival Hyperpigmentaion
Interventions:   Drug: Ascorbic Acid 500 MG;   Device: diode laser
Sponsor:   Ain Shams University
Completed

Thu, 17 Aug 2017 12:00:00 EDT

Preoperative IMRT With Concurrent High-dose Vitamin C and mFOLFOX6 in Locally Advanced Rectal Cancer

Condition:   Rectal Cancer
Intervention:   Drug: Vitamin C
Sponsor:   Zhou Fuxiang
Recruiting

Wed, 17 Mar 2021 12:00:00 EDT

Efficacy of Ascorbic Acid for Prevention of Colistin-Associated Nephrotoxicity

Condition:   Drug Safety
Interventions:   Drug: Colistin;   Drug: Colistin + Ascorbic acid
Sponsors:   Mahidol University;   Siriraj Hospital
Unknown status

Fri, 30 Dec 2011 12:00:00 EST

High Dose Vitamin C in Cardiac Surgery Patients

Conditions:   Disorder of Vitamin C;   Atrial Fibrillation;   Complications Due to Coronary Artery Bypass Graft;   Heart Valve Disease
Interventions:   Drug: Ascorbic Acid;   Drug: Placebo
Sponsor:   Virginia Commonwealth University
Terminated

Wed, 04 May 2016 12:00:00 EDT

Effect of Oral Vitamin C in Assessing the Severity of Oral Mucositis in Chemoradiation of Head and Neck Cancers

Condition:   Oral Mucositis
Interventions:   Drug: Ascorbic Acid;   Drug: Zinc acetate
Sponsors:   Panineeya Mahavidyalaya Institute of Dental Sciences & Research Centre;   Saveetha University;   MNJ Institute of Oncology & Regional cancer Center
Completed

Tue, 16 Aug 2016 12:00:00 EDT

Lessening Organ Dysfunction With VITamin C

Conditions:   Sepsis;   Vitamin C;   Intensive Care Unit;   COVID-19;   Pandemic;   Coronavirus
Interventions:   Drug: Vitamin C;   Other: Control
Sponsors:   Université de Sherbrooke;   Lotte & John Hecht Memorial Foundation
Active, not recruiting

Fri, 21 Sep 2018 12:00:00 EDT

IV Ascorbic Acid in Peritoneal Metastatic Colorectal Cancer

Conditions:   Colorectal Cancer;   Vitamin C;   GLUT3
Interventions:   Drug: Ascorbic acid;   Drug: FOLFOXIRI Protocol
Sponsor:   Fudan University
Recruiting

Tue, 18 Aug 2020 12:00:00 EDT

IV Ascorbic Acid in Advanced Gastric Cancer

Condition:   Gastric Cancer
Interventions:   Drug: ascorbic acid;   Drug: mFOLFOX6
Sponsor:   Sun Yat-sen University
Unknown status

Tue, 10 Jan 2017 12:00:00 EST

A Pilot Study of High-Dose, Intravenous Ascorbic Acid (Vitamin C) to Treat Hepatitis C

Condition:   Hepatitis C
Intervention:   Dietary Supplement: ascorbic acid (vitamin C)
Sponsor:   Health Innovations, Frontier Research Institute
Terminated

Wed, 01 Dec 2010 12:00:00 EST

Assessment of the Effect of Vitamin C on Anemia in Patients With Continuous Ambulatory Peritoneal Dialysis

Condition:   Anemia
Interventions:   Drug: vitamin c;   Drug: placebo
Sponsor:   Shiraz University of Medical Sciences
Completed

Mon, 23 May 2016 12:00:00 EDT

Effect of Vitamin C in Autologous Stem Cell Transplantations

Conditions:   Myeloma Multiple;   Lymphoma
Interventions:   Drug: Vitamin C;   Drug: Placebos
Sponsor:   Maastricht University Medical Center
Recruiting

Tue, 28 May 2019 12:00:00 EDT

Influence of Oral Vitamin C Supplement on the Inflammation Status in Dialysis Patients

Conditions:   Uremia;   Inflammation
Intervention:   Drug: oral vitamin C
Sponsor:   Peking University First Hospital
Completed

Thu, 19 May 2011 12:00:00 EDT

Lessening Organ Dysfunction With VITamin C - COVID-19

Conditions:   Vitamin C;   COVID-19;   Hospitalized Patients
Interventions:   Drug: Vitamin C;   Drug: Control
Sponsors:   Université de Sherbrooke;   Lotte & John Hecht Memorial Foundation
Recruiting

Tue, 26 May 2020 12:00:00 EDT

"Novo C Plus" Vitamin C Containing Dietary Supplement Bioavailability in Healthy Subjects

Condition:   Vitamin C Deficiency
Intervention:   Drug: Ascorbic Acid
Sponsors:   Semmelweis University;   Novonex Pharma Kft
Completed

Tue, 17 Nov 2015 12:00:00 EST

Role of Ascorbic Acid Infusion in Critically Ill Patients With Transfusion Related Acute Lung Injury

Condition:   Acute Lung Injury, Transfusion Related
Interventions:   Drug: Ascorbic Acid Injectable Product;   Drug: Placebo
Sponsors:   Damanhour University;   Alexandria University
Completed

Wed, 06 Nov 2019 12:00:00 EST

Hmong Microbiome ANd Gout, Obesity, Vitamin C (HMANGO-C)

Conditions:   Hyperuricemia;   Gout
Intervention:   Dietary Supplement: Vitamin C
Sponsor:   University of Minnesota
Recruiting

Thu, 24 Jun 2021 12:00:00 EDT

High Dose Vitamin C Intravenous Infusion in Patients With Resectable or Metastatic Solid Tumor Malignancies

Conditions:   Colorectal Cancer;   Pancreatic Cancer;   Lung Cancer
Intervention:   Drug: Vitamin C
Sponsors:   Weill Medical College of Cornell University;   Stand Up To Cancer
Recruiting

Wed, 10 May 2017 12:00:00 EDT

Impact of Rutin and Vitamin C Combination on Oxidative Stress, Insulin Sensitivity and Lipid Profile in Type 2 Diabetic Patients

Condition:   Type 2 Diabetes Mellitus
Interventions:   Dietary Supplement: Rutin in combination with Vitamin C;   Dietary Supplement: Vitamin C
Sponsor:   Ain Shams University
Completed

Mon, 19 Feb 2018 12:00:00 EST

VItamin C in Thermal injuRY: The VICToRY Pilot Trial

Conditions:   Shock;   Thermal Burn
Interventions:   Drug: Ascorbic Acid;   Drug: placebo
Sponsor:   Clinical Evaluation Research Unit at Kingston General Hospital
Recruiting

Thu, 24 Oct 2019 12:00:00 EDT

Pharmacokinetics of Two Different High-dose Regimens of Intravenous Vitamin C in Critically Ill Patients

Conditions:   Multiple Organ Failure;   Sepsis;   Systemic Inflammatory Response Syndrome;   Trauma
Intervention:   Drug: Ascorbic Acid
Sponsor:   VU University Medical Center
Completed

Wed, 27 May 2015 12:00:00 EDT

Vitamin C to Reduce Vasopressor Dose in Septic Shock

Conditions:   Septic Shock;   Sepsis
Interventions:   Drug: Vitamin C;   Drug: Placebos
Sponsor:   Hospital Español de Mexico
Active, not recruiting

Fri, 08 Feb 2019 12:00:00 EST

Ascorbic Acid Treatment in CMT1A Trial (AATIC)

Conditions:   Charcot-Marie-Tooth Disease;   Hereditary Motor and Sensory Neuropathies
Interventions:   Drug: Placebo;   Drug: ascorbic acid
Sponsor:   Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Completed

Wed, 04 Jan 2006 12:00:00 EST

Study on the Effect of Intravenous Ascorbic Acid on Intraoperative Blood Loss in Women With Uterine Myoma

Condition:   Uterine Leiomyoma
Interventions:   Drug: ascorbic acid;   Drug: Normal saline
Sponsor:   Seoul National University Hospital
Completed

Mon, 29 Oct 2012 12:00:00 EDT

Study of High Dose Vitamin C On Outcome in Cardiac Surgery Patients

Condition:   Reperfusion Injury
Interventions:   Drug: Ascorbic Acid;   Other: 5 % Dextrose Water or Normal Saline
Sponsor:   Rutgers, The State University of New Jersey
Completed

Thu, 22 Jul 2010 12:00:00 EDT

Oxalate Formation From Ascorbic Acid

Condition:   Kidney Stone
Interventions:   Dietary Supplement: Low Oxalate Diet;   Dietary Supplement: Carbon-13 Ascorbic Acid Oral Load
Sponsor:   University of Alabama at Birmingham
Not yet recruiting

Tue, 27 Oct 2020 12:00:00 EDT

Combining Active and Passive DNA Hypomethylation

Conditions:   Myelodysplastic Syndromes;   Acute Myeloid Leukemia;   Chronic Myelomonocytic Leukemia
Interventions:   Dietary Supplement: Vitamin C;   Dietary Supplement: Placebo
Sponsors:   Kirsten Grønbæk;   Van Andel Research Institute;   Karolinska University Hospital;   Skane University Hospital;   Sahlgrenska University Hospital, Sweden;   Oslo University Hospital;   Helsinki University Central Hospital;   University of Southern California;   Imperial College London;   University of Copenhagen;   Zealand University Hospital;   Aalborg University Hospital;   Odense University Hospital;   Technical University of Denmark;   Aarhus University Hospital;   Norrland University Hospital;   Uppsala University Hospital
Recruiting

Thu, 27 Jun 2019 12:00:00 EDT

High-Dose Vitamin C Treatment in Critically Ill COVID-19 Patients

Conditions:   Respiratory Distress Syndrome, Adult;   Covid19
Intervention:   Drug: Ascorbic acid
Sponsor:   Sisli Hamidiye Etfal Training and Research Hospital
Completed

Thu, 14 Jan 2021 12:00:00 EST

Trial of Arsenic Trioxide With Ascorbic Acid in the Treatment of Adult Non-Acute Promyelocytic Leukemia (APL) Acute Myelogenous Leukemia

Condition:   Acute Myelogenous Leukemia
Interventions:   Drug: Arsenic Trioxide (ATO);   Drug: Ascorbic Acid
Sponsor:   University of Southern California
Terminated

Fri, 16 Sep 2005 12:00:00 EDT

A Trial to Assess the Impact of Ascorbic Acid on Cardiac Surgeries Outcomes and Complications''

Condition:   Cardiothoracic Surgery
Interventions:   Drug: Ascorbic Acid 500Mg Chew Tab;   Other: Carbonated orange beverage
Sponsor:   El-Galaa Military Medical Complex
Unknown status

Tue, 21 Aug 2018 12:00:00 EDT

Vitamin C in Post-cardiac Arrest

Condition:   Cardiac Arrest
Interventions:   Drug: Vitamin C;   Drug: Thiamine;   Drug: Placebos
Sponsors:   VU University Medical Center;   Gelderse Vallei Hospital;   Sint Franciscus Gasthuis;   Tergooiziekenhuizen;   Amphia Hospital;   Erasmus Medical Center;   Noordwest Ziekenhuisgroep;   Maasstad Hospital;   OLVG
Recruiting

Thu, 26 Apr 2018 12:00:00 EDT

Lessening Organ Dysfunction With VITamin C in Septic ARDS

Conditions:   Septic;   Acute Respiratory Distress Syndrome
Interventions:   Drug: Administration of vitamin C;   Drug: Administration of placebo
Sponsor:   Assistance Publique - Hôpitaux de Paris
Not yet recruiting

Wed, 27 May 2020 12:00:00 EDT

Vitamin C Intravenously With Chemotherapy in Advanced Colorectal Cancer

Condition:   Colorectal Neoplasms
Interventions:   Drug: ascorbic acid;   Drug: Chemotherapy
Sponsor:   Sun Yat-sen University
Unknown status

Mon, 21 Nov 2016 12:00:00 EST

Topical Vitamin C for Treatment of Basal Cell Cancer

Condition:   Basal Cell Carcinoma
Intervention:   Drug: Topical Ascorbic Acid
Sponsor:   Center for Biomedical Research, Inc.
Completed

Fri, 21 Feb 2020 12:00:00 EST

The Effect of Vitamin C on Wound Healing In Mandibular Fracture Patients

Conditions:   Vitamin C Deficiency;   Smoking;   Surgery;   Surgery--Complications;   Wound;   Wound Complication;   Wound Infection;   Wound Dehiscence;   Wound of Skin;   Mandible Fracture;   Mandible Open Fracture;   Mandible Closed Fracture;   Mandibular Fractures;   Ascorbic Acid Deficiency;   Oxidative Stress;   Inflammation
Interventions:   Dietary Supplement: Vitamin C;   Other: Placebo
Sponsors:   Hennepin Healthcare Research Institute;   Regions Hospital;   University of Minnesota
Recruiting

Mon, 06 May 2019 12:00:00 EDT

Vitamin C for the Prevention of UTI in Women Who Undergo Elective Gynecological Surgeries

Condition:   Catheter-Associated Urinary Tract Infection, Ascorbic Acid
Interventions:   Drug: Ascorbic Acid 1000 mg;   Other: Placebo
Sponsor:   American University of Beirut Medical Center
Recruiting

Fri, 07 Feb 2020 12:00:00 EST

The Effect of 1L Polyethylene Glycol Plus Ascorbic Acid With Prepackaged Low-Residue Diet for Bowel Preparation

Conditions:   Colonoscopy;   Colon Polyp;   Bowel Preparation Solutions
Intervention:   Procedure: 1 L PEG with ascorbic acid with prepackaged, low residue diet
Sponsor:   Seoul National University Bundang Hospital
Completed

Mon, 06 Nov 2017 12:00:00 EST

Impact of Ascorbic Acid on Post-Cardiothoracic Surgery Inflammation

Conditions:   Cardiac Surgery;   Inflammation
Interventions:   Drug: Ascorbic acid;   Drug: Placebo
Sponsors:   Hartford Hospital;   The Gustavus and Louise Pfeiffer Research Foundation
Completed

Wed, 22 Aug 2007 12:00:00 EDT

The Effect of Vitamin c on Preventing Complex Regional Pain Syndrome (CRPS Type I) Following Ankle Fracture

Condition:   Ankle Fracture
Interventions:   Dietary Supplement: vitamin c;   Drug: placebo
Sponsor:   Rabin Medical Center
Unknown status

Tue, 19 Apr 2011 12:00:00 EDT

Vitamin C and Atrial Fibrillation After Cardiac Surgery

Condition:   Atrial Fibrillation
Interventions:   Drug: Ascorbic Acid;   Other: Identical Placebo
Sponsor:   Regional Hospital of Scranton
Withdrawn

Thu, 19 Apr 2012 12:00:00 EDT

Early Administration of Vitamin C in Patients With Sepsis or Septic Shock in Emergency Departments

Conditions:   Sepsis;   Septic Shock;   Sepsis, Severe
Interventions:   Drug: Vitamin C;   Drug: Normal saline
Sponsors:   Universitaire Ziekenhuizen Leuven;   Federaal Kenniscentrum voor Gezondheidszorg, Belgium
Recruiting

Wed, 10 Feb 2021 12:00:00 EST

Vitamin C to Decrease Effects of Smoking in Pregnancy on Infant Lung Function

Conditions:   Pulmonary Function; Newborn, Abnormal;   Infant Wheeze;   In-utero Nicotine;   Second Hand Smoke
Interventions:   Dietary Supplement: Vitamin C +prenatal vitamin;   Dietary Supplement: Placebo tablet+prenatal vitamin
Sponsors:   Oregon Health and Science University;   National Heart, Lung, and Blood Institute (NHLBI);   Office of Dietary Supplements (ODS)
Completed

Thu, 08 Nov 2012 12:00:00 EST

Study of Association of Arsenic Trioxide (ATO) and Ascorbic Acid in Myelodysplastic Syndromes

Condition:   Myelodysplastic Syndromes
Intervention:   Drug: ATO + Ascorbic acid
Sponsors:   Fondazione Italiana Sindromi Mielodisplastiche-ETS;   Centro di Riferimento per l'Epidemiologia e la Prev. Oncologica Piemonte
Terminated

Fri, 05 Dec 2008 12:00:00 EST

Steroid, Thiamine and Ascorbic Acid for Comatose Out-of-hospital Cardiac Arrest Survivors

Conditions:   Out-Of-Hospital Cardiac Arrest;   Postcardiac Arrest Syndrome
Interventions:   Drug: The combined supplement of Ascorbic acid, Thiamine, and Cortisol;   Drug: Placebo
Sponsors:   Asan Medical Center;   Seoul St. Mary's Hospital;   Wonju Severance Christian Hospital;   Samsung Changwon Hospital;   Samsung Medical Center;   Chung-Ang University;   Hanyang University;   Ewha Womans University
Recruiting

Thu, 10 Jun 2021 12:00:00 EDT

Vitamin C and Septic Shock

Conditions:   Septic Shock;   Sepsis
Interventions:   Drug: Vitamin C;   Drug: Placebo
Sponsor:   University of Minnesota
Completed

Thu, 09 Nov 2017 12:00:00 EST

The Effect of Vitamin C on Quality of Life of Terminal Cancer Patients

Condition:   Vitamin C Deficiency
Interventions:   Drug: high-dose vitamin C 30gm;   Other: normal saline
Sponsor:   National Taiwan University Hospital
Unknown status

Fri, 21 Jul 2017 12:00:00 EDT

RCT,Double Blind, Placebo to Evaluate the Effect of Zinc and Ascorbic Acid Supplementation in COVID-19 Positive Hospitalized Patients in BSMMU

Condition:   Covid19
Intervention:   Dietary Supplement: zinc gluconate and ascorbic acid
Sponsor:   Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Not yet recruiting

Tue, 22 Sep 2020 12:00:00 EDT

Vitamin C for Severe Thermal Injuries

Condition:   Severe Thermal Injury, Greater Than 20% TBSA
Interventions:   Drug: Vitamin C;   Drug: Placebo
Sponsor:   University of Texas Southwestern Medical Center
Withdrawn

Mon, 30 Apr 2012 12:00:00 EDT

SAFEty Study of Early Infusion of Vitamin C for Treatment of Novel Coronavirus Acute Lung Injury (SAFE EVICT CORONA-ALI)

Conditions:   COVID-19;   Lung Injury, Acute;   Kidney Injury
Interventions:   Drug: L-ascorbic acid;   Other: Placebo
Sponsor:   Virginia Commonwealth University
Recruiting

Tue, 14 Apr 2020 12:00:00 EDT

Effects Of Combination Therapy Of Statin And Ascorbic Acid For Prevention Of Contrast-Induced Nephropathy

Conditions:   Contrast-induced Nephropathy;   Statin;   Ascorbic Acid;   AKI
Interventions:   Drug: Atorvastatin-Ascorbic acid;   Drug: Placebo
Sponsor:   Mansoura University
Completed

Fri, 05 Jan 2018 12:00:00 EST

Treatment of Reperfusion Event by Vitamin C Infusion

Condition:   Angina Pectoris
Interventions:   Drug: Vitamin C;   Drug: Placebo
Sponsor:   University of Roma La Sapienza
Unknown status

Tue, 23 Mar 2010 12:00:00 EDT

the Effect of High Dose Ascorbic Acid on Critically Ill Patients With ARDS

Condition:   Acute Respiratory Distress
Intervention:   Dietary Supplement: vitamin c
Sponsor:   Misr International University
Completed

Wed, 19 Dec 2018 12:00:00 EST

Comparison of Low-volume PEG Plus Ascorbic Acid Versus Standard PEG Solution as Bowel Cleansing for Colonoscopy

Condition:   Colonoscopy [E01.370.372.250.250.200]
Intervention:   Drug: polyethylene glycol, ascorbic acid
Sponsor:   Dong Il Park, M.D, Ph.D.
Unknown status

Tue, 04 Dec 2012 12:00:00 EST

High Dose Vitamin C Combined With Metformin in the Treatment of Malignant Tumors

Conditions:   Hepatocellular Cancer;   Pancreatic Cancer;   Gastric Cancer;   Colorectal Cancer
Interventions:   Drug: Vitamin C;   Drug: Metformin
Sponsor:   Zhongnan Hospital
Recruiting

Thu, 25 Jul 2019 12:00:00 EDT

Vitamin C Infusion for Treatment in Sepsis Induced Acute Lung Injury

Conditions:   Acute Lung Injury;   Sepsis
Interventions:   Drug: Ascorbic Acid;   Drug: Placebo: 5% Dextrose in water
Sponsors:   Virginia Commonwealth University;   National Heart, Lung, and Blood Institute (NHLBI)
Completed

Tue, 08 Apr 2014 12:00:00 EDT

Bioequivalence Study on Vitamin C in Healthy Adults

Condition:   Dietary Exposure
Interventions:   Dietary Supplement: Vitamin C gummy;   Dietary Supplement: Vitamin C tablet
Sponsors:   Church & Dwight Company, Inc.;   KGK Science Inc.
Completed

Wed, 20 Jun 2018 12:00:00 EDT

High Dose Intravenous Ascorbic Acid in Severe Sepsis

Condition:   Sepsis
Interventions:   Drug: Ascorbic Acid;   Other: Normal Saline
Sponsor:   Christiana Care Health Services
Terminated

Tue, 12 Apr 2016 12:00:00 EDT

Vitamin C Efficacy in Reducing Post Operative Pain

Condition:   Gallbladder Inflammation
Intervention:   Drug: Ascorbic Acid
Sponsor:   American University of Beirut Medical Center
Completed

Thu, 24 Mar 2011 12:00:00 EDT

The Effectiveness of High-dose Intravenous Vitamin c With Very Low Carbohydrate Diet for Terminal Colon Cancer Patients

Condition:   Colon Cancer Stage Iv
Interventions:   Drug: Ascorbic Acid;   Other: Control group
Sponsor:   National Taiwan University Hospital
Not yet recruiting

Mon, 29 Jul 2019 12:00:00 EDT

Efficacy of Vitamin C Injection on Fatigue in Workers After Work

Condition:   Fatigue
Interventions:   Dietary Supplement: Ascorbic acid (Vitamin C);   Dietary Supplement: Normal saline
Sponsors:   DongGuk University;   Korean Association For Vitamin Research
Completed

Wed, 12 Mar 2008 12:00:00 EDT

The Effect of High Dose Vitamin C on the Liver Function in Chronic Hepatitis Patients

Conditions:   Chronic Hepatitis;   Chronic Hepatitis C;   Chronic Alcoholic Hepatitis
Intervention:   Drug: High dose vitamin C
Sponsor:   Seoul National University Hospital
Completed

Wed, 10 Aug 2011 12:00:00 EDT

Evaluation of Intravenous Ascorbic Acid

Condition:   Safety and Pharmacokinetics of Intravenous Ascorbate
Intervention:   Drug: IV Vitamin C
Sponsors:   University of Kansas Medical Center;   Thomas Jefferson University
Completed

Tue, 16 Apr 2013 12:00:00 EDT

Pazopanib Hydrochloride With or Without Ascorbic Acid in Treating Patients With Kidney Cancer That Is Metastatic or Cannot Be Removed by Surgery

Conditions:   Clear Cell Renal Cell Carcinoma;   Metastatic Clear Cell Renal Cell Carcinoma;   Stage III Renal Cell Cancer AJCC v8;   Stage IV Renal Cell Cancer AJCC v7;   Unresectable Renal Cell Carcinoma
Interventions:   Drug: Ascorbic Acid;   Drug: Pazopanib Hydrochloride
Sponsors:   Academic and Community Cancer Research United;   National Cancer Institute (NCI)
Terminated

Tue, 07 Nov 2017 12:00:00 EST

High-dose Intravenous Vitamin C as an Adjunctive Treatment for Sepsis in Rwanda

Condition:   Sepsis
Interventions:   Drug: Ascorbic Acid 500Mg/Ml Inj;   Drug: Dextrose in Water
Sponsors:   Virginia Commonwealth University;   University of Rwanda
Not yet recruiting

Fri, 13 Sep 2019 12:00:00 EDT

Coronavirus 2019 (COVID-19)- Using Ascorbic Acid and Zinc Supplementation

Conditions:   COVID;   Corona Virus Infection
Interventions:   Dietary Supplement: Ascorbic Acid;   Dietary Supplement: Zinc Gluconate;   Dietary Supplement: Ascorbic Acid and Zinc Gluconate;   Other: Standard of Care
Sponsor:   The Cleveland Clinic
Completed

Mon, 13 Apr 2020 12:00:00 EDT

Research Study of IV Vitamin C in Combination With Irinotecan vs Irinotecan Alone for Advanced Colorectal CA

Condition:   Stage IV Colorectal Cancer
Interventions:   Drug: Ascorbic Acid;   Drug: Irinotecan
Sponsor:   Thomas Jefferson University
Terminated

Mon, 12 Mar 2012 12:00:00 EDT

A Study of Vitamin C in the Treatment of Liver Cancer to Determine if it is Safe and Effective

Conditions:   Metastatic Hepatocellular Carcinoma;   Advanced Liver Cancer
Interventions:   Drug: Ascorbic Acid + Sorafenib;   Drug: Sorafenib
Sponsor:   Thomas Jefferson University
Completed

Fri, 21 Dec 2012 12:00:00 EST

High Dose Ascorbic Acid (AA) + Nanoparticle Paclitaxel Protein Bound + Cisplatin + Gemcitabine (AA NABPLAGEM) in Patients Who Have Metastatic Pancreatic Cancer

Condition:   Metastatic Pancreatic Cancer
Interventions:   Drug: Ascorbic Acid;   Drug: nab paclitaxel;   Drug: Cisplatin;   Drug: Gemcitabine
Sponsors:   Piedmont Cancer Institute;   Cancer Research UK;   Stand Up To Cancer;   Lustgarten Foundation;   Destroy Pancreatic Cancer;   Translational Genomics Research Institute
Withdrawn

Wed, 09 Jan 2019 12:00:00 EST

High Dose of Vitamin C on Mechanically Ventilated Septic Patients in Intensive Care Unit

Conditions:   Ventilator Associated Pneumonia ( VAP);   Sepsis
Intervention:   Dietary Supplement: Vitamin C
Sponsor:   Ain Shams University
Completed

Tue, 23 Jul 2019 12:00:00 EDT

The Body's Affect on Vitamin C

Condition:   Healthy Volunteers
Intervention:   Other: Vitamin C
Sponsor:   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Completed

Thu, 04 Nov 1999 12:00:00 EST

Comparison of 4L Polyethylene Glycol and 2L Polyethylene Glycol With Ascorbic Acid in Inactive UC Patients

Condition:   Ulcerative Colitis
Interventions:   Drug: polyethylene glycol;   Drug: Ascorbic Acid
Sponsor:   Kyungpook National University Hospital
Completed

Wed, 28 Aug 2013 12:00:00 EDT

The Effect of Melatonin and Vitamin C on COVID-19

Conditions:   Covid19;   SARS-CoV Infection
Interventions:   Dietary Supplement: Vitamin C;   Dietary Supplement: melatonin;   Dietary Supplement: Placebo;   Other: Symptom Survey
Sponsor:   Lancaster General Hospital
Recruiting

Fri, 28 Aug 2020 12:00:00 EDT

Therapy With Hydrocortisone, Ascorbic Acid, Thamine in Patients With Sepsis

Condition:   Sepsis
Interventions:   Drug: Hydrocortisone, Ascorbic acid, Thiamine;   Drug: Normal saline
Sponsors:   Tanta University;   Mostafa Ismail Sharaf;   Salah Eldeen Ibrahim Alsherif;   Mohamed Mohi El deen Abo El yazeed
Completed

Wed, 13 Nov 2019 12:00:00 EST

High Dose Ascorbic Acid Treatment of CMT1A

Condition:   Charcot-Marie-Tooth Disease, Type Ia
Interventions:   Drug: Ascorbic acid (Vitamin C);   Drug: placebo
Sponsors:   Wayne State University;   Muscular Dystrophy Association;   Charcot-Marie-Tooth Association
Completed

Mon, 11 Jun 2007 12:00:00 EDT

Vitamin C and Tyrosine Kinase Inhibitor in Lung Cancer Patients With Epidermal Growth Factor Receptor Mutations

Condition:   Carcinoma, Non-Small-Cell Lung
Interventions:   Drug: Vitamin C;   Drug: Tyrosine kinase inhibitor
Sponsor:   Clifford Hospital, Guangzhou, China
Recruiting

Thu, 10 Jan 2019 12:00:00 EST

The Effect of Phenolic Compounds in Osteoarthritis; a Nutritional Intervention

Condition:   Symptomatic Knee Osteoarthritis
Interventions:   Dietary Supplement: Ascorbic acid / phytochemical supplement;   Dietary Supplement: Ascorbic acid
Sponsor:   Harokopio University
Recruiting

Fri, 05 Mar 2021 12:00:00 EST

High Dose Vitamin C in the Critically Ill Patient

Condition:   Shock
Interventions:   Drug: Ascorbic Acid;   Other: Ringers Lactate or Normal Saline
Sponsor:   Rutgers, The State University of New Jersey
Terminated

Mon, 30 Apr 2012 12:00:00 EDT

Vitamin C as an Anti-cancer Drug

Condition:   Prostatic Neoplasms
Intervention:   Drug: Ascorbic Acid (Vitamin C)
Sponsors:   Copenhagen University Hospital at Herlev;   Rigshospitalet, Denmark;   University of Copenhagen
Completed

Thu, 04 Mar 2010 12:00:00 EST

Vitamin C Supplementation Intervention

Condition:   Heart Failure
Interventions:   Dietary Supplement: Vitamin C 500 mg;   Dietary Supplement: Vitamin C 1000 mg;   Other: Placebo
Sponsors:   University of North Carolina, Chapel Hill;   Sigma Theta Tau International Honor Society of Nursing;   National Institute of Nursing Research (NINR)
Completed

Mon, 29 Jul 2019 12:00:00 EDT

Arsenic Trioxide With Ascorbic Acid and Melphalan for Myeloma Patients

Conditions:   Multiple Myeloma;   Stem Cell Transplantation
Interventions:   Drug: Arsenic Trioxide;   Drug: Melphalan;   Drug: Ascorbic Acid
Sponsors:   M.D. Anderson Cancer Center;   CTI BioPharma
Completed

Fri, 18 Apr 2008 12:00:00 EDT

Mechanisms of Impaired Brain Blood Flow With Aging

Condition:   Aging
Interventions:   Other: Ascorbic Acid;   Other: Normal Saline
Sponsor:   University of Delaware
Active, not recruiting

Thu, 13 Dec 2018 12:00:00 EST

Effect of Vitamin C Upon SSRI-treated OCD Patients

Condition:   OCD
Intervention:   Dietary Supplement: Vitamin C
Sponsor:   Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Unknown status

Tue, 27 Nov 2018 12:00:00 EST

Use of Ascorbic Acid in Patients With COVID 19

Condition:   Hospitalized Patients With Covid-19 Pneumonia
Intervention:   Dietary Supplement: Vitamin C
Sponsor:   University of Palermo
Recruiting

Thu, 26 Mar 2020 12:00:00 EDT

Interest of Ascorbic Acid in the Management of Pneumonia in Elderly People Hospitalized.

Condition:   Pneumonia With Hospitalized Elderly Patient
Interventions:   Drug: Vitamin C;   Drug: Placebo
Sponsor:   University Hospital, Bordeaux
Completed

Thu, 10 Jul 2014 12:00:00 EDT

A Research Trial of High Dose Vitamin C and Chemotherapy for Metastatic Pancreatic Cancer

Condition:   Pancreatic Neoplasms
Intervention:   Drug: Gemcitabine with escalating ascorbic acid
Sponsors:   Joseph J. Cullen;   University of Iowa;   Holden Comprehensive Cancer Center
Completed

Fri, 15 Jan 2010 12:00:00 EST

Ascorbic Acid and Thiamine Effect in Septic Shock

Conditions:   Septic Shock;   Sepsis
Interventions:   Drug: Combination therapy of vitamin C and thiamine;   Drug: Normal saline solution
Sponsors:   Tae Gun Shin;   National Research Foundation of Korea
Completed

Wed, 28 Nov 2018 12:00:00 EST

Impact of Vitamin C on Biomarkers of Neurologic Injury in Survivors of Cardiac Arrest

Conditions:   Heart Arrest, Out-Of-Hospital;   Biomarkers;   Oxidative Stress;   Neurological Injury
Interventions:   Drug: Vitamin C;   Drug: Placebo
Sponsor:   University Medical Centre Maribor
Not yet recruiting

Thu, 24 Sep 2020 12:00:00 EDT

Effect of Vitamin C on Iron Absorption

Condition:   Iron Deficiency
Intervention:   Dietary Supplement: Vitamin C
Sponsor:   Baylor College of Medicine
Completed

Tue, 11 Dec 2007 12:00:00 EST

Evaluating the Effects of Supplemental Vitamin C on Infant Lung Function in Pregnant Smoking Women

Conditions:   Pregnancy;   Smoking
Interventions:   Other: Placebo;   Dietary Supplement: Vitamin C
Sponsors:   Oregon Health and Science University;   National Heart, Lung, and Blood Institute (NHLBI);   National Institute of Environmental Health Sciences (NIEHS)
Completed

Mon, 10 Mar 2008 12:00:00 EDT

Assessment of Gastric pH Changes Induced by Ascorbic Acid Tablets

Condition:   Hypochlorhydria
Interventions:   Drug: Omeprazole 20mg;   Dietary Supplement: Vitamin C
Sponsors:   Indiana University;   Hala Fadda;   Butler University
Not yet recruiting

Mon, 16 Dec 2019 12:00:00 EST

High-dose Ascorbic Acid Intravenous Injection Decreases Mitochondrial DNA Damage in Chronic Fatigue Patients: Randomized-controlled Study

Condition:   Chronic Fatigue
Interventions:   Drug: ascorbic acid 10g/20ml;   Drug: Normal Saline 150ml
Sponsor:   Yonsei University
Unknown status

Tue, 20 Aug 2013 12:00:00 EDT

Epigenetics, Vitamin C, and Abnormal Blood Cell Formation - Vitamin C in Patients With Low-Risk Myeloid Malignancies

Conditions:   Myelodysplastic Syndromes;   Chronic Myelomonocytic Leukemia-1;   Cytopenia
Interventions:   Dietary Supplement: Vitamin C (ascorbic acid);   Other: Placebo
Sponsors:   Rigshospitalet, Denmark;   Van Andel Research Institute;   University of Southern California;   Imperial College London;   University of Copenhagen;   Odense University Hospital;   Technical University of Denmark;   Aalborg University Hospital
Recruiting

Mon, 24 Sep 2018 12:00:00 EDT

Vitamin C in Atrial Fibrillation Ablation

Condition:   Atrial Fibrillation Ablation
Interventions:   Drug: Vitamin C;   Other: Placebo
Sponsor:   Virginia Commonwealth University
Completed

Wed, 10 May 2017 12:00:00 EDT

Vitamin C Infusion for TReatment in Sepsis and Alcoholic Hepatitis

Conditions:   Alcoholic Hepatitis;   Sepsis
Interventions:   Drug: Vitamin C;   Drug: Dextrose 5% in water
Sponsors:   Virginia Commonwealth University;   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting

Mon, 04 Feb 2019 12:00:00 EST

Effect of Fish Oil and Vitamin C on Exercise-Induced Bronchoconstriction and Airway Inflammation in Asthma

Condition:   Asthma
Interventions:   Dietary Supplement: Fish Oil;   Dietary Supplement: Ascorbic Acid;   Dietary Supplement: Fish Oil Placebo;   Dietary Supplement: Ascorbic Acid Placebo
Sponsor:   Indiana University
Completed

Wed, 27 Jan 2010 12:00:00 EST

Influence of Vitamin C on Post-operative Atrial Fibrillation

Condition:   Atrial Fibrillation
Interventions:   Dietary Supplement: Vitamin C;   Other: Placebo
Sponsor:   Algemeen Ziekenhuis Maria Middelares
Unknown status

Thu, 19 Jul 2018 12:00:00 EDT

Trial of Ascorbic Acid (AA) + Nanoparticle Paclitaxel Protein Bound + Cisplatin + Gemcitabine (AA NABPLAGEM)

Conditions:   Pancreatic Cancer;   Pancreas Cancer;   Pancreatic Adenocarcinoma Resectable;   Pancreatic Ductal Adenocarcinoma;   Pancreas Metastases
Interventions:   Drug: Ascorbic Acid;   Drug: Paclitaxel protein-bound;   Drug: Cisplatin;   Drug: Gemcitabine
Sponsors:   HonorHealth Research Institute;   Stand Up To Cancer;   Cancer Research UK;   Lustgarten Foundation;   Translational Genomics Research Institute;   Princeton University;   Salk Institute for Biological Studies;   Cold Spring Harbor Laboratory;   Barts Cancer Institute;   University of Arizona;   Imaging Endpoints
Active, not recruiting

Thu, 25 Jan 2018 12:00:00 EST

Safety of Antioxidants During GYN Cancer Care

Conditions:   Ovarian Cancer;   Cervical Cancer;   Uterine Cancer
Intervention:   Drug: vitamin C
Sponsors:   Jeanne Drisko, MD, CNS, FACN;   University of Kansas Medical Center
Completed

Tue, 31 Jan 2006 12:00:00 EST

Antioxidants in Gestational Diabetes

Condition:   Gestational Diabetes Mellitus
Intervention:   Drug: L-ascorbic acid
Sponsor:   Cairo University
Completed

Wed, 04 Feb 2015 12:00:00 EST

High Dose Ascorbic Acid and Nanoparticle Paclitaxel Protein Bound and Cisplatin and Gemcitabine (AA NABPLAGEM) in Patients Who Have Metastatic Pancreatic Cancer

Conditions:   Metastatic Pancreatic Cancer;   Pancreatic Cancer;   Pancreas Cancer;   Pancreatic Adenocarcinoma Resectable;   Pancreatic Ductal Adenocarcinoma;   Pancreatic Metastasis
Interventions:   Drug: Ascorbic Acid;   Drug: Paclitaxel protein-bound;   Drug: Cisplatin;   Drug: Gemcitabine
Sponsors:   Medical College of Wisconsin;   Cancer Research UK;   Stand Up To Cancer;   Lustgarten Foundation;   Destroy Pancreatic Cancer;   Translational Genomics Research Institute;   HonorHealth Research Institute
Withdrawn

Tue, 09 Apr 2019 12:00:00 EDT

Vitamin C for Prevention of Urinary Tract Infections in the Spinal Cord Injured

Conditions:   Urinary Tract Infection;   Spinal Cord Injury
Intervention:   Drug: vitamin C
Sponsors:   Sunnaas Rehabilitation Hospital;   Dentsply Sirona Implants
Terminated

Thu, 26 Mar 2009 12:00:00 EDT

High Dose Ascorbic Acid (AA) + Nanoparticle Paclitaxel Protein Bound + Cisplatin + Gemcitabine (AA NABPLAGEM) in Patients Who Have Metastatic Pancreatic Cancer

Conditions:   Metastatic Pancreatic Cancer;   Pancreatic Cancer;   Pancreas Cancer;   Pancreatic Adenocarcinoma Resectable;   Pancreatic Ductal Adenocarcinoma;   Pancreatic Metastasis
Interventions:   Drug: Ascorbic Acid;   Drug: Paclitaxel protein-bound;   Drug: Cisplatin;   Drug: Gemcitabine
Sponsors:   Hitendra Patel;   Cancer Research UK;   Stand Up To Cancer;   Lustgarten Foundation;   Destroy Pancreatic Cancer;   Translational Genomics Research Institute;   HonorHealth Research Institute
Withdrawn

Fri, 05 Oct 2018 12:00:00 EDT

Vitamin C, Thiamine and Hydrocortisone for the Treatment of Septic Shock

Condition:   Septic Shock
Interventions:   Drug: Vitamin C,thiamine,hydrocortisone;   Drug: Placebo
Sponsor:   Northern Jiangsu Province People's Hospital
Completed

Tue, 12 Mar 2019 12:00:00 EDT

Temozolomide and Ascorbic Acid in Treating Patients With Recurrent High-Grade Glioma

Conditions:   Anaplastic Astrocytoma;   Anaplastic Oligodendroglioma;   Anaplastic Oligoastrocytoma;   Glioblastoma;   Gliosarcoma
Interventions:   Dietary Supplement: ascorbic acid;   Drug: temozolomide;   Other: quality-of-life assessment;   Other: laboratory biomarker analysis
Sponsors:   University of Nebraska;   National Cancer Institute (NCI)
Terminated

Fri, 20 Jun 2014 12:00:00 EDT

Quantitative in Vivo Biomarkers of Oxidative Stress in Diabetes

Conditions:   Type 2 Diabetes;   Oxidative Stress
Intervention:   Biological: ascorbic acid (Vitamin C)
Sponsor:   In-Young Choi, Ph.D.
Completed

Wed, 18 Feb 2009 12:00:00 EST

Vitamin C Depigmenattion Versus Conventional Technique

Condition:   Melanin Hyperpigmentation
Intervention:   Dietary Supplement: vitamin c depigementation
Sponsor:   Cairo University
Completed

Thu, 25 Oct 2018 12:00:00 EDT

Can Vitamin C Reduce the Risk of Postoperative Shoulder Stiffness?

Condition:   Shoulder Stiffness
Interventions:   Drug: Vitamin C;   Drug: Placebo
Sponsor:   Lindenhofgruppe AG
Recruiting

Wed, 15 Jul 2020 12:00:00 EDT

Effects of Vitamin C Administration on Extravascular Lung Water in Patients With Severe Features of Preeclampsia

Conditions:   Preeclampsia Severe;   Preeclampsia Postpartum
Interventions:   Drug: Vitamin C;   Drug: placebo
Sponsor:   University Medical Centre Ljubljana
Completed

Thu, 01 Mar 2018 12:00:00 EST

Cephalon Decitabine, Arsenic Trioxide and Ascorbic Acid for Myelodysplastic Syndrome

Condition:   Myelodysplastic Syndrome
Intervention:   Drug: Decitabine, Arsenic Trioxide and Ascorbic Acid
Sponsors:   Duke University;   Cephalon;   Eisai Inc.
Completed

Fri, 22 Feb 2008 12:00:00 EST

Comparison of Ascorbic Acid and Grape Seed Extract in Oxidative Stress Induced by on Pump Heart Surgery

Condition:   CABG-Induced Oxidative Stress
Interventions:   Drug: GSE;   Drug: Vit C (Ascorbic Acid)
Sponsor:   Tabriz University
Unknown status

Mon, 09 Feb 2009 12:00:00 EST

Effect of Glutamine and Vitamin C on Interleukin-6 and Clinical Outcomes in Surgical Intensive Care Unit Patients

Condition:   Critical Care
Intervention:   Dietary Supplement: Glutamine and vitamin C enteral supplement
Sponsor:   Chung Shan Medical University
Completed

Thu, 25 May 2017 12:00:00 EDT

Safety and Efficacy of Vitamin C Infusion in Combination With Local mEHT to Treat Non Small Cell Lung Cancer

Conditions:   Carcinoma, Non-Small-Cell Lung;   Stage IIIA Non-small Cell Lung Cancer;   Stage IIIB Non-small Cell Lung Cancer;   Stage IV Non-small Cell Lung Cancer;   Recurrent Non-small Cell Lung Cancer
Interventions:   Drug: vitamin C;   Device: Modulated Electro-Hyperthermia (mEHT);   Other: Supportive care
Sponsor:   Clifford Hospital, Guangzhou, China
Completed

Thu, 14 Jan 2016 12:00:00 EST

Role of Vitamin C to Augment Iron Chelation With DFP or DFX

Conditions:   Vitamin c;   Thalassemia Major;   Iron Chelation
Interventions:   Drug: Vitamin C, Defriprone, deferisarox;   Drug: deferiprone , deferesarox
Sponsor:   Ain Shams University
Unknown status

Tue, 11 Mar 2014 12:00:00 EDT

High Doses Vitamin C and Tissular Repair in Surgical Patients

Condition:   Tissue Damage
Interventions:   Dietary Supplement: Vitamin C;   Other: Placebo
Sponsors:   Universidad San Francisco de Quito;   Biomolec Pharma
Completed

Fri, 21 May 2021 12:00:00 EDT

Ascorbic Acid, Corticosteroids, and Thiamine in Sepsis (ACTS) Trial

Conditions:   Sepsis;   Septic Shock;   Metabolic Disturbance
Interventions:   Drug: vitamin C, vitamin B1, hydrocortisone;   Drug: Normal saline
Sponsors:   Beth Israel Deaconess Medical Center;   Open Philanthropy Project
Completed

Wed, 03 Jan 2018 12:00:00 EST

Tolerance of Two Forms of Vitamin C in Acid-sensitive Adults

Condition:   Tolerance
Interventions:   Dietary Supplement: Calcium ascorbate;   Dietary Supplement: Ascorbic acid
Sponsors:   NBTY, Inc.;   KGK Science Inc.;   Moyad, Mark MD MPH
Completed

Mon, 10 Jun 2013 12:00:00 EDT

Trial of Vitamin C as Add on Therapy for Children With Idiopathic Epilepsy

Condition:   Idiopathic Epilepsy
Intervention:   Dietary Supplement: Vitamin C
Sponsor:   Ain Shams University
Unknown status

Tue, 24 Feb 2015 12:00:00 EST

Sympathetic-vascular Dysfunction in Obesity and Insulin Resistance (Vitamin C Study)

Conditions:   Hypertension;   Cardiovascular Diseases
Interventions:   Drug: Ascorbic acid solution (American Regent Laboratories Inc.);   Drug: Saline
Sponsor:   University of Kansas Medical Center
Recruiting

Wed, 20 Jan 2021 12:00:00 EST

Trial of Chemotherapy Plus Intravenous Vitamin C in Patients With Advanced Cancer for Whom Chemotherapy Alone is Only Marginally Effective

Condition:   Cancer
Intervention:   Dietary Supplement: vitamin C (ascorbic acid)
Sponsor:   Jewish General Hospital
Completed

Fri, 15 Jan 2010 12:00:00 EST

Colon Cleansing Quality of Polyethylene Glycol Compared With Polyethylene Glycol Plus Ascorbic Acid.

Condition:   Colonoscopy Preparation
Interventions:   Drug: Polyethylene glycol 4000;   Drug: Macrogol 3350 plus ascorbic acid
Sponsor:   Fundación Canaria Rafael Clavijo para la Investigación Biomédica
Completed

Thu, 27 Feb 2014 12:00:00 EST

Comparative Bioavailability of Two Forms of Vitamin C

Condition:   Bioavailability
Interventions:   Dietary Supplement: calcium ascorbate;   Dietary Supplement: ascorbic acid;   Other: placebo
Sponsors:   NBTY, Inc.;   KGK Science Inc.;   Moyad, Mark MD MPH
Completed

Tue, 14 May 2013 12:00:00 EDT

Vitamin C, Vitamin B1 and Steroid in Sepsis

Condition:   Sepsis, Severe
Interventions:   Drug: Ascorbic acid-Vitamin B1-Hydrocortisone;   Drug: Placebo
Sponsor:   Far Eastern Memorial Hospital
Unknown status

Wed, 31 Jul 2019 12:00:00 EDT

Effect of Grape Seed Extract Plus Ascorbic Acid on Endothelial Function

Condition:   Coronary Artery Disease
Intervention:   Dietary Supplement: Grape seed extract and ascorbic acid
Sponsor:   Boston University
Completed

Tue, 06 Nov 2007 12:00:00 EST

Cognitive and Cerebral Blood Flow Effects of Vitamin C

Conditions:   Endothelial Function;   Cognition
Intervention:   Dietary Supplement: Vitamin C
Sponsor:   Northumbria University
Completed

Mon, 25 Jan 2010 12:00:00 EST

Influence of Endothelial Function on Central and Peripheral Causes Of Exercise Impairment in Type 2 Diabetes

Condition:   Type 2 Diabetes
Interventions:   Behavioral: Exercise program;   Drug: Ascorbic Acid (Vitamin C)
Sponsors:   University of Colorado, Denver;   American Diabetes Association;   National Institutes of Health (NIH)
Completed

Wed, 05 Nov 2008 12:00:00 EST

Sodium Picosulphate/Magnesium Citrate and Low-volume PEG -Ascorbic Acid as Preparation for Colonoscopy

Condition:   Colon Cleansing for Colonoscopy
Interventions:   Drug: sodium picosulphate magnesium citrate;   Drug: low-volume PEG -ascorbic acid
Sponsor:   ASST Fatebenefratelli Sacco
Completed

Tue, 22 May 2012 12:00:00 EDT

Role of Vitamin C in Cardiac Vasoplegia After Cardiopulmonary Bypass

Condition:   to Study the Effect of Vitamin C Administration on the Amount and the Time of Weaning of Noradrenaline Given Post-operatively to Patients After CPB
Intervention:   Drug: IV of vitamin C
Sponsor:   Cairo University
Recruiting

Wed, 19 Aug 2020 12:00:00 EDT

Alcohol Abuse or Alcohol Withdrawal: Risk of Latent Scurvy

Condition:   Alcoholics
Intervention:   Drug: Vitamin C
Sponsor:   SCP Battistelli
Completed

Thu, 15 Mar 2018 12:00:00 EDT

Clinical Trial of High-dose Vitamin C for Advanced Pancreatic Cancer

Conditions:   Pancreatic Neoplasms;   Pancreatic Cancer
Intervention:   Drug: Gemcitabine with escalating ascorbic acid
Sponsors:   Joseph J. Cullen;   Susan L Bader Foundation of Hope;   Holden Comprehensive Cancer Center;   National Cancer Institute (NCI)
Terminated

Mon, 23 Jan 2012 12:00:00 EST

Combination Method Using Sodium Picosulfate and Magnesium Citrate and PEG With Ascorbic Acid for Bowel Preparation

Conditions:   Bowel Preparation;   Sodium Picosulfate and Magnesium Citrate;   Polyethylene Glycol With Ascorbic Acid
Intervention:   Drug: sodium picosulfate and magnesium citrate, polyethylene glycol with ascorbic acid
Sponsor:   National Cancer Center, Korea
Completed

Thu, 01 Dec 2016 12:00:00 EST

Effect of Vitamin C and E in Breast Cancer Patients Undergoing Chemotherapy

Condition:   Breast Cancer
Intervention:   Drug: Vitamin C, Vitamin E
Sponsor:   Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Recruiting

Thu, 09 Jul 2020 12:00:00 EDT

Study of High-Dose Intravenous (IV) Vitamin C Treatment in Patients With Solid Tumors

Condition:   Cancer
Intervention:   Drug: Ascorbic Acid
Sponsor:   Midwestern Regional Medical Center
Completed

Wed, 28 Feb 2007 12:00:00 EST

Topical Tranexamic Acid Versus Topical Vitamin C With Microneedling in Periorbital Hyperpigmentation; Comparative Study

Condition:   Periorbital Hyperpigmentation
Interventions:   Drug: vitamin c 20%;   Drug: Tranexamic acid 5mg/ml
Sponsor:   Kasr El Aini Hospital
Completed

Wed, 06 Jan 2021 12:00:00 EST

Effectiveness of Ascorbic Acid and Tocopherol for Depression in Elderly.

Condition:   Depression
Interventions:   Drug: Ascorbic Acid;   Drug: Alpha tocopherol;   Drug: PLACEBO
Sponsor:   Yolanda de Diego Otero
Completed

Wed, 08 Jun 2016 12:00:00 EDT

Vitamin C & Thiamine in Sepsis

Conditions:   Sepsis;   Septic Shock
Interventions:   Drug: Vitamin C;   Drug: Vitamin B1
Sponsor:   Saint Francis Care
Recruiting

Thu, 19 Jul 2018 12:00:00 EDT

Compare Effects of EpiCor and Vitamin C to Vitamin C Alone on the Common Cold or Influenza in Healthy Children

Condition:   Signs and Symptoms, Respiratory
Interventions:   Dietary Supplement: EpiCor and Vitamin C;   Dietary Supplement: Vitamin C
Sponsors:   Cargill;   Clinres Farmacija d.o.o.;   PharmaLinea d.o.o.;   Diagnostic Laboratory Medicare PLUS d.o.o.;   Embria Health Sciences
Completed

Tue, 17 Sep 2019 12:00:00 EDT

The Impact of Vitamin C on Postoperative Acute Kidney Injury in Risk Patients Undergoing Valvular Heart Surgery

Condition:   Acute Kidney Injury
Interventions:   Drug: Vitamin C;   Drug: Control (Normal saline)
Sponsor:   Yonsei University
Recruiting

Tue, 24 Dec 2019 12:00:00 EST

First-day High Dose Vitamin C, E in Severe Birth Asphyxia

Condition:   Birth Asphyxia
Intervention:   Drug: Vitamin E, Vitamin C
Sponsor:   Sir Takhtasinhji General Hospital
Completed

Thu, 06 Dec 2012 12:00:00 EST

Role of Vitamin C at 6 Months on Incidence of Complex Regional Pain Syndrome Type I in Upper Limb Surgery

Condition:   Complex Regional Pain Syndrome (CRPS) TYPE I
Interventions:   Drug: Vitamin C;   Drug: Placebo
Sponsor:   Centre Hospitalier Universitaire, Amiens
Recruiting

Tue, 17 Mar 2015 12:00:00 EDT

Epigenetics, Vitamin C and Abnormal Hematopoiesis - Pilot Study

Conditions:   Myelodysplastic Syndrome;   Acute Myeloid Leukemia
Interventions:   Dietary Supplement: Vitamin C;   Dietary Supplement: Placebo
Sponsors:   Rigshospitalet, Denmark;   Van Andel Research Institute
Completed

Wed, 24 Aug 2016 12:00:00 EDT

Arsenic Trioxide With or Without Ascorbic Acid in Treating Patients With Myelofibrosis

Conditions:   Essential Thrombocythemia;   Polycythemia Vera;   Primary Myelofibrosis
Interventions:   Drug: Arsenic Trioxide;   Dietary Supplement: Ascorbic Acid;   Other: Laboratory Biomarker Analysis;   Other: Pharmacological Study
Sponsors:   Roswell Park Cancer Institute;   National Cancer Institute (NCI);   Cephalon
Terminated

Tue, 17 Nov 2009 12:00:00 EST

Trisenox, Ascorbic Acid and Bortezomib in Patients With Relapsed/Refractory Multiple Myeloma

Condition:   Multiple Myeloma
Intervention:   Drug: Arsenic Trioxide, Ascorbic Acid and Bortezomib
Sponsors:   Duke University;   Cephalon
Terminated

Thu, 10 Jan 2008 12:00:00 EST

Oral Vitamin C for Correction of Anemia in Patients Receiving Peritoneal Dialysis

Conditions:   Anemia;   Peritoneal Dialysis
Interventions:   Dietary Supplement: Vitamin C;   Dietary Supplement: placebo
Sponsor:   Unity Health Toronto
Completed

Mon, 15 Jun 2009 12:00:00 EDT

The Effects of Vitamin E and Vitamin C and Exercise

Condition:   Exercise and Non-exercise Effect Upon Vitamins E and C
Intervention:   Dietary Supplement: Vitamin E and Vitamin C
Sponsor:   USDA Grand Forks Human Nutrition Research Center
Terminated

Wed, 08 Jun 2011 12:00:00 EDT

High-dose Intravenous Vitamin C (HDIVC) as Adjuvant Therapy in Critical Patients With Positive COVID-19. A Pilot Randomized Controlled Dose-comparison Trial.

Condition:   Covid19
Interventions:   Drug: High doses of intravenous vitamin C;   Drug: Dextrose 500 mL
Sponsor:   Hugo Galindo
Not yet recruiting

Tue, 31 Aug 2021 12:00:00 EDT

Comparing the Use of Vitamin c (Ascorbic Acid) in Eye Burn in Subconjunctival Injection to Topical or Oral Treatment.

Condition:   Burn
Intervention:   Dietary Supplement: vitamin c
Sponsors:   The Baruch Padeh Medical Center, Poriya;   Rambam Health Care Campus;   Soroka University Medical Center
Withdrawn

Thu, 14 Aug 2008 12:00:00 EDT

Tolerability and Efficacy of Sodium Picosulfate/Magnesium Citrate Versus PEG/Ascorbic Acid in Ulcerative Colitis Patients

Condition:   Ulcerative Colitis
Interventions:   Drug: Sodium Picosulfate/Magnesium Citrate Laxative;   Drug: 2L polyethylene glycol/ascorbic acid
Sponsor:   American University of Beirut Medical Center
Unknown status

Tue, 10 Jul 2018 12:00:00 EDT

Vitamin C Supplementation Plus Hypoglycemic Agents Versus Hypoglycemic Agents Alone in Type 2 Diabetes Mellitus

Condition:   Type 2 Diabetes Mellitus
Interventions:   Dietary Supplement: Vitamin C;   Drug: glyburide
Sponsor:   Al-Neelain University
Unknown status

Tue, 22 Mar 2011 12:00:00 EDT

Bevacizumab and Ascorbic Acid in Patients Treating With Recurrent High Grade Glioma

Conditions:   Glioblastoma;   Glioma
Interventions:   Dietary Supplement: Ascorbic Acid;   Biological: Bevacizumab;   Other: Laboratory Biomarker Analysis;   Other: Quality-of-Life Assessment
Sponsors:   University of Nebraska;   National Cancer Institute (NCI)
Terminated

Thu, 14 Jul 2016 12:00:00 EDT

Vitamin C Supplementation as a Preventive Treatment of Diabetic Peripheral Neuropathy

Condition:   Diabetic Neuropathies
Interventions:   Dietary Supplement: Vitamin C;   Dietary Supplement: Placebo
Sponsor:   Washington State University
Completed

Thu, 13 Mar 2008 12:00:00 EDT

The Vitamin C, Hydrocortisone and Thiamine in Patients With Septic Shock Trial

Conditions:   Shock, Septic;   Critically Ill;   Vasoplegic Syndrome;   Sepsis
Interventions:   Drug: Vitamin C;   Drug: Thiamine;   Drug: Hydrocortisone,
Sponsors:   Australian and New Zealand Intensive Care Research Centre;   Austin Hospital, Melbourne Australia;   Melbourne Health;   Barwon Health;   Monash Health;   The Alfred;   Wellington Hospital;   Western Health, Australia
Completed

Mon, 06 Nov 2017 12:00:00 EST

Vitamin C & Exercise Induced Bronchoconstriction (EIB)

Condition:   Exercise-induced Bronchospasm
Interventions:   Dietary Supplement: Vitamin C;   Other: Placebo
Sponsor:   University of Kansas Medical Center
Withdrawn

Wed, 01 Aug 2018 12:00:00 EDT

Outcome Following Vitamin C Administration in Sepsis

Condition:   Severe Sepsis
Interventions:   Drug: Vitamin C;   Drug: placebo
Sponsor:   Lawson Health Research Institute
Unknown status

Wed, 02 May 2012 12:00:00 EDT

Metabolic Resuscitation Using Ascorbic Acid, Thiamine, and Glucocorticoids in Sepsis.

Conditions:   Sepsis, Severe;   Septic Shock
Interventions:   Drug: Ascorbic Acid;   Drug: Thiamine;   Drug: Hydrocortisone;   Drug: Sodium Chloride 0.9%
Sponsor:   Community Medical Center, Toms River, NJ
Completed

Mon, 05 Feb 2018 12:00:00 EST

Preoperative Melatonin or Vitamin C Administration on Postoperative Analgesia

Condition:   Postoperative Pain
Interventions:   Drug: Melatonin;   Drug: Vitamin C;   Other: Placebo
Sponsor:   Cukurova University
Completed

Thu, 24 Dec 2015 12:00:00 EST

Role of Mega Dose of Vitamin C in Critical COVID-19 Patients

Condition:   Corona Virus Infection
Intervention:   Drug: Vitamin C
Sponsor:   University of Lahore
Recruiting

Wed, 23 Dec 2020 12:00:00 EST

Effect of Vitamin C on Postoperative Pain After Laparoscopic Cholecystectomy

Conditions:   Chronic Cholecystitis;   Cholelithiasis
Interventions:   Drug: Vitamin C;   Drug: Placebo
Sponsor:   Taeho Hong
Unknown status

Thu, 17 Sep 2015 12:00:00 EDT

Efficacy of Microneedling With Topical Vitamin C in Treatment of Acne Scarring

Conditions:   Acne Vulgaris;   Acne Scars
Interventions:   Device: Dermaroller;   Drug: Topical Vitamin C
Sponsor:   Sohag University
Completed

Mon, 14 May 2018 12:00:00 EDT

Influence of Hesperidin and Vitamin C on Uric Acid Concentration

Conditions:   Higher Uric Acid Concentrations (>5,5 mg/dl);   Healthy
Interventions:   Dietary Supplement: Control;   Dietary Supplement: Hesperidin;   Dietary Supplement: Vitamin C;   Dietary Supplement: Hesperidin + Vitamin C
Sponsors:   University of Kiel;   Hochschule Geisenheim University
Not yet recruiting

Fri, 20 Mar 2020 12:00:00 EDT

Effect of IV Vitamin C, Thiamine, and Steroids on Mortality of Septic Shock

Condition:   Septic Shock
Interventions:   Drug: Vitamin C;   Drug: Normal saline
Sponsor:   New York Presbyterian Brooklyn Methodist Hospital
Terminated

Mon, 04 Feb 2019 12:00:00 EST

Impact of Vitamin C on Endothelial Function and Exercise Capacity in Fontan-Palliated Patients

Conditions:   Fontan Procedure;   Hypoplastic Left Heart Syndrome;   Tricuspid Atresia
Interventions:   Dietary Supplement: Vitamin C;   Dietary Supplement: Placebo
Sponsors:   University of Michigan;   Griese-Hutchinson Champions for Children's Hearts Investigator Award
Completed

Thu, 10 Sep 2009 12:00:00 EDT

Use of ARINA-1 in an Intermediate Size Patient Population of Bilateral Lung Transplant Patients With CLAD Grade 0

Condition:   Lung Transplant
Intervention:   Drug: Ascorbic Acid
Sponsor:   Duke University
Completed

Fri, 21 Jul 2017 12:00:00 EDT

Soft Tissue Augmentation Using CAF With Either SCTG and Vitamin C Versus SCTG Alone in Management of RT1 Gingival Recession

Condition:   Gingival Thickness
Interventions:   Procedure: CAF with SCTG and Vitamin C injection;   Procedure: CAF with SCTG alone
Sponsor:   Cairo University
Recruiting

Tue, 17 Nov 2020 12:00:00 EST

A Phase 2, Pharmacokinetic (PK) Study of 6R-BH4 Alone or 6R-BH4 With Vitamin C in Subjects With Endothelial Dysfunction

Condition:   Endothelial Dysfunction
Interventions:   Drug: Sapropterin Dihydrochloride;   Drug: Sapropterin Dihydrochloride and Vitamin C
Sponsor:   BioMarin Pharmaceutical
Completed

Thu, 20 Sep 2007 12:00:00 EDT

Vitamin C Level Effect in Orthognathic Surgery

Conditions:   Maxillofacial Abnormalities;   Maxillofacial Injuries;   Maxillofacial Trauma
Intervention:   Other: Vitamin C
Sponsor:   Medipol University
Recruiting

Thu, 04 Jun 2020 12:00:00 EDT

Effect of Intravenous Vitamin C on SOFA Score Among Septic Patients

Condition:   Sepsis
Interventions:   Drug: vitamin C, vitamin B1;   Drug: vitamin B1
Sponsor:   Indonesia University
Completed

Thu, 24 Oct 2019 12:00:00 EDT

Daily vs. Every Other Day Oral Iron Supplementation in Patients With Absolute Iron Deficiency Anemia

Conditions:   Anemia;   Iron Deficiency Anemia
Interventions:   Drug: Ferrous Sulfate 300Mg Tablet;   Drug: Vitamin C 500Mg tablet
Sponsors:   Sunnybrook Health Sciences Centre;   Unity Health Toronto
Recruiting

Wed, 31 Oct 2018 12:00:00 EDT

Vitamin C and Cardiovascular Risk

Conditions:   Atherosclerosis;   Type 2 Diabetes
Intervention:   Dietary Supplement: Vitamin C
Sponsors:   University of New Mexico;   American Diabetes Association
Completed

Mon, 24 Sep 2007 12:00:00 EDT

Pilot Trial of Intravenous Vitamin C in Refractory Non-Hodgkin Lymphoma (NHL)

Condition:   Non-Hodgkin Lymphoma
Intervention:   Drug: Intravenous vitamin C
Sponsor:   Sidney Kimmel Cancer Center at Thomas Jefferson University
Terminated

Fri, 29 Feb 2008 12:00:00 EST

Evaluation of Safety and Dosing of a Vitamin C Bundle for Sepsis Treatment in Africa

Conditions:   Sepsis;   Septic Shock;   HIV
Interventions:   Drug: Vitamin C;   Drug: Vitamin B1
Sponsors:   Liverpool School of Tropical Medicine;   Infectious Diseases Institute, Uganda;   Walimu;   University of Copenhagen;   University of Liverpool
Recruiting

Tue, 10 Aug 2021 12:00:00 EDT

"Liposomal Encapsulated Vitamin C in Complex Regional Pain Syndrome"

Condition:   Complex Regional Pain Syndrome I of Lower Limb
Interventions:   Dietary Supplement: liposomal vitamin C;   Dietary Supplement: standard vitamin C;   Dietary Supplement: placebo
Sponsor:   Centre Hospitalier de Ham
Completed

Wed, 18 Dec 2019 12:00:00 EST

The Effect of Vitamin C on Growth Hormone Secretion

Conditions:   Obese;   Disorder of Vitamin C;   Growth Hormone Secretion Abnormality
Interventions:   Dietary Supplement: Placebo;   Dietary Supplement: Vitamin C 250 mg once daily;   Dietary Supplement: Vitamin C 1,000 mg once daily
Sponsor:   Massachusetts General Hospital
Withdrawn

Thu, 23 Feb 2012 12:00:00 EST

Does Vitamin C Reduce Finger Stiffness After Distal Radius Fractures?

Conditions:   Finger Stiffness;   Distal Radius Fracture
Interventions:   Drug: 500 mg vitamin c, 1 pill per day for 6 weeks;   Drug: 1 placebo pill for 6 weeks
Sponsor:   Massachusetts General Hospital
Completed

Fri, 15 Aug 2014 12:00:00 EDT

Vitamin C as an Adjunct in Periodontal Treatment in Type 2 Diabetes Mellitus Patients

Conditions:   Diabetes Mellitus Type 2 With Hyperglycemia;   Periodontitis
Interventions:   Drug: Vitamin C 500 MG Oral Capsule;   Other: placebo
Sponsor:   Mahidol University
Unknown status

Fri, 01 Sep 2017 12:00:00 EDT

Evaluation of the Effect of Incorporation of Vitamin C Into Platelet Rich Fibrin Scaffold in Treatment of Intra-osseous Periodontal Defects

Condition:   Periodontal Bone Loss
Intervention:   Combination Product: combination of vitamin C and platelet rich fibrin
Sponsor:   Cairo University
Unknown status

Tue, 16 Oct 2018 12:00:00 EDT

Ascorbic Acid and Ibuprofen in Infants With Hypoxic Ischemic Encephalopathy

Conditions:   Hypoxic Ischemic Encephalopathy;   Perinatal Asphyxia
Interventions:   Drug: Ascorbic acid (vitamin C);   Drug: Ibuprofen;   Drug: Placebo
Sponsor:   Al-Azhar University
Completed

Thu, 28 Feb 2008 12:00:00 EST

Reducing Frailty for Older Cancer Survivors Using Supplements

Conditions:   Frailty;   Inflammation
Intervention:   Drug: Epigallocatechin-3-Gallate (EGCG) plus Ascorbic Acid (Vitamin C)
Sponsor:   University of Rochester
Recruiting

Thu, 17 Sep 2020 12:00:00 EDT

New Treatment Option for Pancreatic Cancer

Condition:   Pancreatic Cancer
Interventions:   Drug: Intravenous Vitamin C;   Drug: Gemcitabine
Sponsors:   Jeanne Drisko, MD, CNS, FACN;   Lotte & John Hecht Memorial Foundation;   University of Kansas Medical Center
Completed

Thu, 02 Jun 2011 12:00:00 EDT

The Effectiveness of Vitamin C in Postoperative Pain Management of Single-level Posterior Lumbar Interbody Fusion (PLIF)

Condition:   Fusion of Spine (Disease)
Interventions:   Drug: Vitamin C;   Drug: Placebo drug
Sponsor:   Seoul National University Hospital
Completed

Wed, 30 Apr 2014 12:00:00 EDT

Effects of Vitamin C and E on Endothelial Function in Adolescent Diabetes

Condition:   Type 1 Diabetes Mellitus
Interventions:   Dietary Supplement: Vitamin C;   Dietary Supplement: Vitamin E
Sponsor:   Nationwide Children's Hospital
Completed

Tue, 24 Dec 2013 12:00:00 EST

High-dose Intravenous Vitamin C in Patients With Septic Shock

Conditions:   Sepsis, Severe;   Septic Shock
Intervention:   Drug: Sodium Ascorbate
Sponsors:   Melbourne Health;   Monash Medical Centre;   The Florey Institute of Neuroscience and Mental Health;   University of Melbourne
Not yet recruiting

Mon, 15 Mar 2021 12:00:00 EDT

Effects of Hydrolyzed Collagen and Vitamin C on Explosive Performance

Conditions:   Collagen Synthesis;   Rate of Force (RFD) Development
Interventions:   Dietary Supplement: Collagen and Vitamin C powder mix nutritional intervention;   Other: Maltodextrin placebo powder;   Other: Maximum power training exercise
Sponsor:   PepsiCo Global R&D
Completed

Thu, 18 Jun 2020 12:00:00 EDT

Thiamine, Vitamin C and Hydrocortisone in the Treatment of Septic Shock

Condition:   Septic Shock
Intervention:   Dietary Supplement: Thiamine and Vitamin C
Sponsor:   Spectrum Health - Lakeland
Unknown status

Wed, 30 May 2018 12:00:00 EDT

Differences by Sex and Genotype in the Effects of Stress on Executive Functions

Condition:   Stress
Interventions:   Drug: Methylphenidate;   Drug: Vitamin C
Sponsors:   University of British Columbia;   National Institute on Drug Abuse (NIDA)
Recruiting

Tue, 18 Feb 2020 12:00:00 EST

Vitamin C, Steroids, and Thiamine, and Cerebral Autoregulation and Functional Outcome in Septic Shock

Condition:   Septic Shock
Interventions:   Drug: Stress-dose Hydrocortisone plus Vitamin C;   Drug: isotonic sodium chloride solution placebo plus isotonic sodium chloride solution placebo
Sponsor:   University of Athens
Recruiting

Tue, 28 Aug 2018 12:00:00 EDT

Contrast Agent-associated Nephrotoxicity in Intensive Care Unit Patients

Condition:   Contrast Induced Nephropathy
Intervention:   Drug: N-acetylcysteine and ascorbic acid
Sponsor:   University of Thessaly
Unknown status

Mon, 23 Nov 2009 12:00:00 EST

Nitrate and Vitamin C on Vascular Health Oxidative Stress

Condition:   Endothelial Dysfunction
Interventions:   Dietary Supplement: Dietary nitrate in the form of beetroot juice for all participnats;   Dietary Supplement: Nature Made vitamin c 1000 mg;   Dietary Supplement: Placebo
Sponsor:   David Travis Thomas
Completed

Tue, 25 Feb 2020 12:00:00 EST

A Long-term Study to Describe the Use of PASCORBIN® 7.5 g in Patients With Vitamin C Deficiency

Conditions:   Vitamin C Deficiency;   Acute Disease;   Chronic Disease
Intervention:   Drug: vitamin C
Sponsor:   Pascoe Pharmazeutische Praeparate GmbH
Recruiting

Wed, 22 Apr 2015 12:00:00 EDT

Docetaxel With or Without Ascorbic Acid in Treating Patients With Metastatic Prostate Cancer

Conditions:   Hormone-Resistant Prostate Cancer;   Metastatic Prostate Carcinoma;   Stage IV Prostate Cancer
Interventions:   Dietary Supplement: Ascorbic Acid;   Drug: Docetaxel;   Other: Laboratory Biomarker Analysis;   Other: Pharmacological Study;   Other: Placebo;   Other: Quality-of-Life Assessment
Sponsors:   Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins;   National Cancer Institute (NCI)
Recruiting

Thu, 06 Aug 2015 12:00:00 EDT

Clinical Utility of Endothelial Dysfunction in PAD

Condition:   Peripheral Arterial Disease
Interventions:   Drug: atorvastatin;   Drug: ascorbic acid;   Drug: Placebo
Sponsor:   Boston University
Terminated

Tue, 26 Jun 2007 12:00:00 EDT

the Efficacy and Safety of Vitamin C for Iron Supplementation in Adult IDA Patients

Condition:   Anemia, Iron-Deficiency
Interventions:   Drug: ferrous succinate and vitamin C;   Drug: ferrous succinate
Sponsor:   Huashan Hospital
Completed

Wed, 16 Dec 2015 12:00:00 EST

Ascorbic Acid and Combination Chemotherapy in Treating Patients With Locally Advanced or Recurrent Pancreatic Cancer That Cannot Be Removed by Surgery

Conditions:   Pancreatic Adenocarcinoma;   Recurrent Pancreatic Carcinoma;   Stage III Pancreatic Cancer;   Stage IV Pancreatic Cancer;   Unresectable Pancreatic Carcinoma
Interventions:   Drug: Oxaliplatin;   Drug: Irinotecan Hydrochloride;   Drug: Leucovorin Calcium;   Drug: Fluorouracil;   Dietary Supplement: Ascorbic Acid
Sponsor:   Sidney Kimmel Cancer Center at Thomas Jefferson University
Completed

Mon, 12 Sep 2016 12:00:00 EDT

Role of Antioxidants (Vitamin C and E) in the Management of Schizophrenia

Condition:   Schizophrenia
Intervention:   Dietary Supplement: Antioxidants (Vitamin C, E )
Sponsor:   University of Health Sciences Lahore
Completed

Wed, 04 Sep 2019 12:00:00 EDT

Vitamin C, Hydrocortisone and Thiamine for Septic Shock

Condition:   Shock, Septic
Interventions:   Drug: Combined Vitamin C and Stress-Dose Hydrocortisone;   Drug: Placebo plus placebo
Sponsors:   University of Athens;   General Hospital of Nikaia "Saint Panteleimon";   Naval Hospital, Athens
Recruiting

Thu, 19 Jul 2018 12:00:00 EDT

Hydroxychloroquine for COVID-19 Post-exposure Prophylaxis (PEP)

Conditions:   COVID-19;   Corona Virus Infection;   SARS (Severe Acute Respiratory Syndrome);   SARS-CoV-2
Interventions:   Drug: Hydroxychloroquine Sulfate;   Drug: Ascorbic Acid
Sponsors:   University of Washington;   Bill and Melinda Gates Foundation
Completed

Wed, 01 Apr 2020 12:00:00 EDT

Effect of Resveratrol and Vitamin C on Insulin Resistance Among Postmenopausal Women

Conditions:   Postmenopausal;   Insulin Resistance
Interventions:   Dietary Supplement: vitamin C (500 mg / day) + placebo;   Dietary Supplement: resveratrol (500 mg / day) + placebo;   Dietary Supplement: vitamin C (500 mg / day) and resveratrol (500 mg / day)
Sponsor:   Instituto Nacional de Perinatologia Isidro Espinosa de los Reyes
Unknown status

Mon, 27 Mar 2017 12:00:00 EDT

The Effect of High Dose Vitamin C in Burn Patients

Condition:   Burns
Interventions:   Drug: Intravenous Vitamin C;   Drug: Vitamin C
Sponsors:   United States Army Institute of Surgical Research;   University of Miami
Withdrawn

Mon, 10 Jul 2006 12:00:00 EDT

Intravenous Vitamin C in Combination With Standard Chemotherapy for Pancreatic Cancer

Condition:   Metastatic Pancreatic Cancer
Interventions:   Drug: Gemcitabine and Erlotinib;   Dietary Supplement: Intravenous Vitamin C
Sponsor:   Sidney Kimmel Cancer Center at Thomas Jefferson University
Completed

Fri, 07 Aug 2009 12:00:00 EDT

Vitamin C, Thiamine, Cyanocobalamine, Pyridoxine and Hydrocortisone in Sepsis

Conditions:   Sepsis;   Septic Shock
Interventions:   Drug: Vitamin C;   Drug: Hydrocortisone;   Drug: Complex B
Sponsor:   IMSS Hospital General de Zona 11, Piedras Negras
Completed

Thu, 12 Dec 2019 12:00:00 EST

Antioxidant Vitaminas and Hypertrophy Adaptations to Resistance Training

Condition:   Hypertrophy
Interventions:   Dietary Supplement: Vitamin C and vitamin E;   Dietary Supplement: Placebo
Sponsor:   Universidad Europea de Madrid
Completed

Fri, 02 Apr 2021 12:00:00 EDT

The Effect of Liposome Vitamin C on the Absorption and Metabolism of the Human Body.

Condition:   Vitamin C Deficiency
Interventions:   Dietary Supplement: vitamin C without liposome;   Dietary Supplement: liposomal process A vitamin C;   Dietary Supplement: liposomal process B vitamin C (Double Nutri™)
Sponsor:   TCI Co., Ltd.
Completed

Fri, 14 May 2021 12:00:00 EDT

Zinc and Green Tea Extract for Community Respiratory Viral Infections

Condition:   Respiratory Viral Infection
Intervention:   Drug: zinc-green tea extract-ascorbic acid
Sponsor:   University of Missouri-Columbia
Not yet recruiting

Mon, 24 May 2021 12:00:00 EDT

Oral Arsenic Trioxide for Newly Diagnosed Acute Promyelocytic Leukaemia

Condition:   Acute Promyelocytic Leukemia
Intervention:   Drug: Oral arsenic Trioxide, ATRA and ascorbic acid
Sponsor:   The University of Hong Kong
Recruiting

Fri, 10 Aug 2018 12:00:00 EDT

Iron Supplementation in Hip/Knee Surgery (SIDERAL)

Conditions:   Orthopedic Disorder;   Hip Arthropathy;   Knee Arthropathy;   Anemia;   Iron Poor Blood
Intervention:   Dietary Supplement: Sucrosomial iron plus ascorbic acid
Sponsor:   Istituto Ortopedico Galeazzi
Completed

Fri, 06 Sep 2019 12:00:00 EDT

Ph 2 Trial of Vitamin C & G-FLIP (Low Doses Gemcitabine, 5FU, Leucovorin, Irinotecan, Oxaliplatin) for Pancreatic Cancer

Condition:   Pancreatic Cancer
Interventions:   Drug: G-FLIP;   Drug: G-FLIP-DM;   Dietary Supplement: Vitamin C
Sponsor:   Bruckner Oncology
Completed

Tue, 23 Jul 2013 12:00:00 EDT

High Dose Ascorbic Acid for Plasma Cell Disorders

Condition:   Multiple Myeloma
Interventions:   Other: Ascorbate;   Drug: Melphalan
Sponsors:   Michael Tomasson;   University of Iowa
Recruiting

Thu, 26 Jul 2018 12:00:00 EDT

Collagen Vitamin C Dose Response Performance

Condition:   Healthy Volunteers
Interventions:   Dietary Supplement: Hydrolyzed collagen;   Dietary Supplement: Vitamin C;   Dietary Supplement: Optimized Hydrolyzed Collagen and Vitamin C;   Dietary Supplement: Gummy Placebo
Sponsor:   University of California, Davis
Completed

Tue, 26 Sep 2017 12:00:00 EDT

Efficacy of Vitamin C Supplement vs Spinal Manipulation to Treatment in Lateral Epicondylitis

Conditions:   Lateral Epicondylitis;   Tennis Elbow
Interventions:   Combination Product: Vitamin C;   Combination Product: spinal manipulation;   Combination Product: Transcutaneous electrical nerve stimulation (TENS)
Sponsor:   Universidad Rey Juan Carlos
Enrolling by invitation

Wed, 24 Jun 2020 12:00:00 EDT

Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Sepsis and Septic Shock

Condition:   Sepsis
Interventions:   Drug: Hydrocortisone, Vitamin C, and Thiamine;   Other: Normal saline
Sponsor:   Zhujiang Hospital
Completed

Wed, 23 Aug 2017 12:00:00 EDT

Does Vitamins C and E Supplementation of After Preterm Rupture of Membranes Prolong the Duration of Latency? A Prospective Randomized Controlled Study

Condition:   Preterm Premature Rupture of Membranes
Intervention:   Drug: vitamine C and E
Sponsor:   Erzincan Military Hospital
Completed

Fri, 24 Dec 2010 12:00:00 EST

The Effect of Vitamin C on GCF Total Oxidant Capacity in Smoker Patients With Periodontitis

Condition:   Vitamin C Deficiency
Intervention:   Drug: Vitamin C
Sponsor:   Cairo University
Recruiting

Tue, 17 Aug 2021 12:00:00 EDT

Restless Legs Syndrome in Hemodialysis Patients

Condition:   Restless Leg Syndrome
Interventions:   Other: Vitamin C;   Other: Placebo
Sponsor:   Makassed General Hospital
Completed

Thu, 09 Nov 2017 12:00:00 EST

Study of Vitamin C, Vitamin E and Their Combination to Treat Restless Legs Syndrome in Hemodialysis Patients

Conditions:   Restless Legs Syndrome;   Kidney Failure, Chronic
Interventions:   Drug: Vitamin C & Vitamin E;   Drug: Vitamin C;   Drug: Vitamin E;   Drug: Vitamin C Placebo & Vitamin E Placebo
Sponsor:   Shiraz University of Medical Sciences
Completed

Tue, 18 May 2010 12:00:00 EDT

Hydroxychloroquine in Patients With Newly Diagnosed COVID-19 Compared to Standard of Care

Conditions:   COVID-19;   Corona Virus Infection;   SARS-CoV-2;   2019-nCoV;   2019 Novel Coronavirus
Interventions:   Drug: Hydroxychloroquine;   Dietary Supplement: Vitamin C
Sponsors:   Providence Health & Services;   Center for Outcomes Research and Education;   Providence Cancer Center, Earle A. Chiles Research Institute
Suspended

Mon, 06 Apr 2020 12:00:00 EDT

Effects of Vitamin C on Hyperoxia-Induced Reduction of Retinal Blood Flow

Conditions:   Ocular Physiology;   Regional Blood Flow
Interventions:   Dietary Supplement: vitamin C (Mayrhofer) 24mg/min i.v. for 64 min;   Dietary Supplement: Placebo;   Other: 100% O2 (AGA) two times for 12 min
Sponsor:   Medical University of Vienna
Completed

Thu, 10 Jul 2008 12:00:00 EDT

Effect of Age and Fitness on Vascular Function and Oxidative Stress During Acute Inflammation

Conditions:   Aging;   Inflammation
Intervention:   Biological: Typhoid Vaccine/Ascorbic Acid
Sponsor:   University of Illinois at Chicago
Terminated

Tue, 26 Mar 2019 12:00:00 EDT

Hyperglycemia and Oxidative Stress in the Human Brain With Diabetes

Condition:   Type 2 Diabetes
Intervention:   Dietary Supplement: Vitamin C
Sponsor:   In-Young Choi, Ph.D.
Terminated

Mon, 20 Oct 2008 12:00:00 EDT

Preventing COVID-19 in Healthcare Workers With HCQ: A RCT

Condition:   Covid-19
Interventions:   Drug: Hydroxychloroquine;   Other: Vitamin C
Sponsor:   Stony Brook University
Withdrawn

Wed, 15 Apr 2020 12:00:00 EDT

Arsenic Trioxide Plus Vitamin C in Treating Patients With Recurrent or Refractory Multiple Myeloma

Condition:   Multiple Myeloma and Plasma Cell Neoplasm
Interventions:   Dietary Supplement: ascorbic acid;   Drug: arsenic trioxide
Sponsors:   University of Miami;   National Cancer Institute (NCI)
Completed

Mon, 27 Jan 2003 12:00:00 EST

Efficacy and Safety of High-dose Vitamin C Combined With Chinese Medicine Against Coronavirus Pneumonia (COVID-19)

Condition:   COVID-19
Interventions:   Drug: Alpha-interferon alpha, abidol, ribavirin, Buzhong Yiqi plus and minus formula, Huhuang Detoxicity Paste, Baimu Qingre Jiedu Paste, fumigation/inhalation of vitamin C;   Drug: Alpha-interferon, abidol, ribavirin, Buzhong Yiqi plus and minus formula, Huhuang Detoxicity Paste, Baimu Qingre Jiedu Paste and 5% glucose;   Drug: Alpha-interferon, abidol, ribavirin, Buzhong Yiqi plus and minus formula, Huhuang Detoxicity Paste, Baimu Qingre Jiedu Paste and high-dose vitamin C treatment
Sponsor:   Xi'an International Medical Center Hospital
Active, not recruiting

Fri, 11 Dec 2020 12:00:00 EST

Arsenic Trioxide, Ascorbic Acid, Dexamethasone, and Thalidomide in Myelofibrosis/Myeloproliferative Disorder

Conditions:   Chronic Myeloproliferative Disorders;   Leukemia;   Myelodysplastic Syndromes;   Myelodysplastic/Myeloproliferative Diseases
Interventions:   Dietary Supplement: ascorbic acid;   Drug: arsenic trioxide;   Drug: dexamethasone;   Drug: thalidomide
Sponsor:   Case Comprehensive Cancer Center
Completed

Wed, 11 Jan 2006 12:00:00 EST

Vitamin C and Liraglutide Effects on Hypoglycemia-induced Oxidative Stress, Inflammation and Endothelial Dysfunction in Type 1 Diabetes.

Condition:   Type 1 Diabetes Mellitus
Interventions:   Drug: Vitamine C;   Drug: Liraglutide 6 mg
Sponsor:   Anna Cruceta
Withdrawn

Wed, 09 Apr 2014 12:00:00 EDT

Effects of Antioxidant Dentifrice on Gingivitis

Condition:   Gingivitis
Interventions:   Drug: Experimental toothpaste;   Drug: Control toothpaste
Sponsors:   Lion Corporation;   Osaka University;   Tohoku University;   Nihon University
Completed

Wed, 02 Apr 2014 12:00:00 EDT

Vitamin C Infusion for the Treatment of Severe 2019-nCoV Infected Pneumonia

Conditions:   Vitamin C;   Pneumonia, Viral;   Pneumonia, Ventilator-Associated
Interventions:   Drug: VC;   Drug: Sterile Water for Injection
Sponsor:   ZhiYong Peng
Terminated

Tue, 11 Feb 2020 12:00:00 EST

Fluorescence-guided Surgery for Low- and High-grade Gliomas

Condition:   Glioma
Interventions:   Drug: 5-Aminolevulinic acid (ALA);   Drug: Placebo - ascorbic acid
Sponsor:   St. Joseph's Hospital and Medical Center, Phoenix
Unknown status

Fri, 30 Dec 2011 12:00:00 EST

The Effect of Vitamin C, Thiamine and Hydrocortisone on Clinical Course and Outcome in Patients With Severe Sepsis and Septic Shock

Conditions:   Sepsis;   Septic Shock;   Critical Illness;   Fluid Overload
Interventions:   Drug: Vitamin C;   Drug: Hydrocortisone;   Drug: Thiamine;   Drug: 0.9% Sodium Chloride Injection
Sponsor:   University Medical Centre Ljubljana
Terminated

Tue, 07 Nov 2017 12:00:00 EST

Safety & Efficacy Study of Gemcitabine...With High Dose IV Vit. C (HDIVC)

Condition:   Metastatic Adenocarcinoma of the Pancreas
Intervention:   Drug: Gemcitabine, Intravenous and oral Ascorbic Acid (Vitamin C)
Sponsor:   Eastern Regional Medical Center
Terminated

Wed, 01 Aug 2012 12:00:00 EDT

Clinical Trial for Asses the Safety and Efficacy of Vitamin C and Vitamin E in Combination Versus Placebo for Treating Cognitive and Behavior Disorder in Children With Fragile X Syndrome

Condition:   X Fragile Syndrome
Interventions:   Drug: Vitamin C 10mg/Kg Vitamin E 10 mg/Kg;   Drug: Placebo
Sponsors:   Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud;   Delos Clinical
Unknown status

Mon, 24 Oct 2016 12:00:00 EDT

Vitamin C Supplement for Lumbar Spine Surgery

Condition:   Lumbar Spine Surgery
Interventions:   Dietary Supplement: Vitamin C;   Dietary Supplement: Placebo
Sponsor:   University of Kansas Medical Center
Recruiting

Wed, 17 Apr 2019 12:00:00 EDT

Safety and Efficacy Study of Antioxidants for the Treatment of the Fragile X Syndrome

Condition:   Fragile X Syndrome
Interventions:   Dietary Supplement: Ascorbic Acid (Vitamin C) and Alpha-tocopherol (Vitamin E);   Dietary Supplement: Placebo
Sponsor:   Yolanda de Diego Otero
Completed

Wed, 06 Apr 2011 12:00:00 EDT

Combined Antioxidant and Preeclampsia Prediction Studies (CAPPS)

Condition:   Preeclampsia
Interventions:   Drug: Dietary Supplement/Vitamins;   Drug: Placebo for Vitamin C and Vitamin E
Sponsors:   The George Washington University Biostatistics Center;   National Heart, Lung, and Blood Institute (NHLBI);   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Completed

Fri, 26 Aug 2005 12:00:00 EDT

Vitamin C Versus Nitric Oxide in Prolonged Ventilation

Condition:   ARDS
Interventions:   Drug: Vitamin C;   Drug: Nitric Oxide;   Device: ventilators
Sponsor:   King Abdul Aziz Specialist Hospital
Completed

Tue, 02 Jun 2020 12:00:00 EDT

Efficacy Evaluation of 16 Weeks' Dietary Supplementation With Iron Bis-glycinate Plus Vitamin C on Cognitive Function, Subjective Mood, Fatigue, Health and Well-being

Conditions:   Cognitive Function and Mood;   Non-anaemic Iron Deficiency
Interventions:   Dietary Supplement: Iron Bis-Glycinate Chelate and Vitamin C;   Dietary Supplement: Iron Bis-Glycinate Chelate;   Dietary Supplement: Placebo
Sponsors:   Northumbria University;   Bayer
Completed

Mon, 13 Jul 2020 12:00:00 EDT

Local Vasoconstriction in Postural Tachycardia Syndrome

Condition:   Postural Tachycardia Syndrome
Interventions:   Drug: Losartan;   Drug: Ascorbic Acid (Vitamin C);   Drug: Normal Saline
Sponsor:   New York Medical College
Completed

Tue, 28 Sep 2010 12:00:00 EDT

Arsenic Trioxide, Thalidomide, Dexamethasone, and Ascorbic Acid in Treating Patients With Relapsed or Refractory Multiple Myeloma

Condition:   Multiple Myeloma and Plasma Cell Neoplasm
Interventions:   Dietary Supplement: ascorbic acid;   Drug: arsenic trioxide;   Drug: dexamethasone;   Drug: thalidomide
Sponsors:   OHSU Knight Cancer Institute;   National Cancer Institute (NCI)
Terminated

Wed, 28 Sep 2005 12:00:00 EDT

Prophylaxis to Reduce Postoperative Atrial Fibrillation in Cardiac Surgery

Conditions:   Atrial Fibrillation;   Atrial Flutter
Interventions:   Drug: beta blockers;   Drug: amiodarone;   Drug: ascorbic acid
Sponsor:   MaineHealth
Completed

Thu, 06 Aug 2009 12:00:00 EDT

Vitamin C for Prophylaxis of Post-operative Atrial Fibrillation in On-pump Cardiac Surgery Procedures

Condition:   Atrial Fibrillation
Interventions:   Drug: Vitamin C;   Drug: L-Carnitine;   Drug: Placebo
Sponsor:   Attikon Hospital
Completed

Wed, 21 Apr 2010 12:00:00 EDT

Bortezomib, Ascorbic Acid, and Melphalan in Treating Patients With Newly Diagnosed Multiple Myeloma

Condition:   Multiple Myeloma and Plasma Cell Neoplasm
Interventions:   Dietary Supplement: ascorbic acid;   Drug: bortezomib;   Drug: melphalan
Sponsor:   Oncotherapeutics
Completed

Tue, 25 Apr 2006 12:00:00 EDT

Postoperative Pain After Intravenous Vitamin C Injection for Arthroscopic Rotator Cuff Repair

Condition:   Rotator Cuff Tear
Interventions:   Drug: Intravenous Nutrition (Vitamins) injection;   Drug: Intravenous Saline injection
Sponsor:   Himchan Hospital
Unknown status

Wed, 14 Dec 2016 12:00:00 EST

16 Weeks' Dietary Supplementation With Iron and Iron + Vitamin C on Cerebral Blood Flow and Energy Expenditure in Women of Reproductive Age

Conditions:   Iron;   Cerebral Blood Flow;   Energy Metabolism;   Cognitive Function
Interventions:   Dietary Supplement: Iron bis-glycinate chelate and vitamin C;   Dietary Supplement: Iron bis-glycinate chelate;   Dietary Supplement: Placebo
Sponsors:   Northumbria University;   Bayer
Completed

Mon, 20 Jul 2020 12:00:00 EDT

Zinc, Chromium, Vitamin C, and Copper Combination Supplement for Prediabetes Progression

Conditions:   PreDiabetes;   Nutrition
Interventions:   Dietary Supplement: Zinc, Chromium, Vitamin C, and Copper Supplementation;   Behavioral: Standard healthy lifestyle intervention;   Other: Placebo
Sponsors:   Indonesia University;   Blackmores Institute
Recruiting

Thu, 13 Aug 2020 12:00:00 EDT

The Safety and Effectiveness of Different Doses of Vitamin C in HIV-Infected Patients

Condition:   HIV Infections
Intervention:   Drug: Oral Vitamin C
Sponsor:   National Institute of Allergy and Infectious Diseases (NIAID)
Withdrawn

Fri, 31 Aug 2001 12:00:00 EDT

Oxidative Stress and Opiorphin in Temporomandibular Disorders

Condition:   Temporomandibular Disorders
Interventions:   Device: stabilization splint;   Drug: Placebo Oral Tablet;   Device: placebo splint;   Dietary Supplement: Vitamin C
Sponsor:   Croatian Science Foundation
Unknown status

Tue, 24 Jan 2017 12:00:00 EST

Steroids, Thiamine and Ascorbic Acid in Septic Shock

Condition:   Septic Shock
Intervention:   Drug: STASIS
Sponsors:   Baqiyatallah Medical Sciences University;   Hamadan University of Medical Science;   Tehran University of Medical Sciences
Unknown status

Tue, 22 Oct 2019 12:00:00 EDT

Evaluation of the Effect of Body Weight and Composition on Iron Absorption and Blood Volume

Condition:   Obesity
Interventions:   Dietary Supplement: labeled iron solution;   Dietary Supplement: labeled iron solution and ascorbic acid
Sponsors:   Swiss Federal Institute of Technology;   Wageningen University;   Universidad de Monterrey
Completed

Mon, 24 Jun 2013 12:00:00 EDT

Ascorbic Acid and Combination Chemotherapy for the Treatment of Relapsed or Refractory Lymphoma or Clonal Cytopenia of Undetermined Significance

Conditions:   Clonal Cytopenia of Undetermined Significance;   High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements;   Recurrent Diffuse Large B-Cell Lymphoma;   Recurrent Hodgkin Lymphoma;   Recurrent Lymphoma;   Refractory Diffuse Large B-Cell Lymphoma;   Refractory Lymphoma
Interventions:   Dietary Supplement: Ascorbic Acid;   Drug: Carboplatin;   Drug: Cisplatin;   Drug: Cytarabine;   Drug: Dexamethasone;   Drug: Etoposide;   Drug: Gemcitabine Hydrochloride;   Drug: Ifosfamide;   Other: Laboratory Biomarker Analysis;   Drug: Oxaliplatin;   Other: Placebo Administration;   Other: Questionnaire Administration;   Biological: Rituximab
Sponsors:   Mayo Clinic;   National Cancer Institute (NCI)
Recruiting

Thu, 01 Feb 2018 12:00:00 EST

Effect of Antioxidant Vitamins on Coagulopathy and Nosocomial Pneumonia After Severe Trauma

Conditions:   Coagulopathy;   Nosocomial Pneumonia
Interventions:   Dietary Supplement: Vitamin C;   Dietary Supplement: Vitamin E;   Dietary Supplement: Saline (for Vitamin C);   Drug: Placebo (for Vitamin E)
Sponsor:   University of Alabama at Birmingham
Terminated

Fri, 12 Jul 2013 12:00:00 EDT

Comparative Study on the Effects of Sublingual Misoprostol in Addition to Standard AMTSL in Low Risk Parturients in LASUTH, Ikeja.

Condition:   Primary Postpartum Haemorrhage
Interventions:   Drug: Misoprostol;   Drug: vitamin c
Sponsor:   Lagos State University
Unknown status

Wed, 22 Apr 2015 12:00:00 EDT

Vitamin Therapy in JGH Patients

Conditions:   Patients With Hypovitaminosis C and D;   Vitamin Deficiencies
Intervention:   Dietary Supplement: vitamin C or vitamin D
Sponsors:   Jewish General Hospital;   McGill University
Completed

Thu, 28 Jun 2012 12:00:00 EDT

Comparison of Polyethylene Glycol With Ascorbic Acid and Oral Sulfate Solution for Bowel Preparation

Condition:   Healthy
Interventions:   Drug: HAPREP®;   Drug: SUCLEAR®
Sponsors:   National Cancer Center, Korea;   Daehang Hospital
Completed

Wed, 16 Sep 2015 12:00:00 EDT

Triple Therapy in Septic Shock Patients

Conditions:   Septic Shock;   Sepsis;   Organ Dysfunction Syndrome Sepsis
Intervention:   Drug: vitamin c - thiamine- hydrocortisone
Sponsor:   Air Force Specialized Hospital, Cairo, Egypt
Completed

Tue, 11 Aug 2020 12:00:00 EDT

Impact of a Predictive Score of Bowel Preparation Quality in Clinical Practice

Condition:   Cleansing Quality of the Colon
Interventions:   Drug: polyethylene glycol;   Drug: polyethylene glycol plus ascorbic acid
Sponsor:   Hospital Universitario de Canarias
Completed

Tue, 05 Feb 2019 12:00:00 EST

A Phase 2 Trial of High-Dose Ascorbate in Glioblastoma Multiforme

Condition:   Glioblastoma Multiforme
Interventions:   Drug: Temozolomide;   Radiation: radiation therapy;   Drug: Ascorbic Acid
Sponsors:   Bryan Allen;   Holden Comprehensive Cancer Center;   National Cancer Institute (NCI)
Active, not recruiting

Thu, 22 Jan 2015 12:00:00 EST

A Study to Demonstrate the Efficacy and Tolerability of Ferrous Bisglycinate Chelate in Iron Deficiency Anaemia and to Compare These With Those of Ferrous Ascorbate.

Condition:   Haematopoiesis
Interventions:   Drug: ferrous ascorbate;   Dietary Supplement: ferrous bisglycinate chelate 1 OD;   Dietary Supplement: ferrous bisglycinate chelate 2 OD
Sponsor:   GlaxoSmithKline
Completed

Mon, 12 Jul 2010 12:00:00 EDT

Vitamin C, Thiamine, and Steroids in Sepsis

Condition:   Sepsis
Interventions:   Drug: Vitamin C;   Drug: Thiamine;   Drug: Hydrocortisone;   Drug: Vitamin C Placebo;   Drug: Thiamine Placebo;   Drug: Hydrocortisone Placebo
Sponsors:   Emory University;   The Marcus Foundation
Completed

Thu, 26 Apr 2018 12:00:00 EDT

Velcade, Trisenox, Vitamin C and Melphalan for Myeloma Patients

Condition:   Myeloma
Interventions:   Drug: Trisenox (Arsenic Trioxide);   Drug: Velcade (Bortezomib);   Drug: Melphalan;   Drug: Vitamin C (Ascorbic Acid)
Sponsors:   M.D. Anderson Cancer Center;   Cephalon
Completed

Fri, 04 May 2007 12:00:00 EDT

Arsenic Trioxide and Ascorbic Acid Combined With Bortezomib, Thalidomide, and Dexamethasone in Treating Patients With Relapsed or Refractory Multiple Myeloma or Plasma Cell Leukemia

Condition:   Multiple Myeloma and Plasma Cell Neoplasm
Interventions:   Dietary Supplement: ascorbic acid;   Drug: arsenic trioxide;   Drug: bortezomib;   Drug: dexamethasone;   Drug: thalidomide;   Drug: Aspirin
Sponsors:   Barbara Ann Karmanos Cancer Institute;   National Cancer Institute (NCI)
Completed

Thu, 24 Nov 2005 12:00:00 EST

A Study of Melphalan, BCNU, Vitamin B12b, Vitamin C, and Stem Cell Infusion in People With Advanced Pancreatic Cancer and BRCA Mutations

Conditions:   Pancreatic Adenocarcinoma Metastatic;   BRCA1 Mutation;   BRCA2 Mutation
Interventions:   Drug: Melphalan;   Drug: BCNU;   Drug: Vitamin B12B;   Drug: Vitamin C;   Drug: Ethanol;   Device: Autologous Hematopoietic Stem Cells
Sponsor:   General Oncology, Inc.
Recruiting

Mon, 04 Nov 2019 12:00:00 EST

Evaluation of The Effect of Rutin and Vitamin C on the Oxidative Stress in Hemodialysis Patients

Condition:   End Stage Renal Disease
Intervention:   Drug: RUTA C 60
Sponsor:   Ain Shams University
Recruiting

Thu, 08 Jul 2021 12:00:00 EDT

Does Ascorbic Acid Reduce Sympathoexcitation in CHF?

Condition:   Heart Failure
Interventions:   Drug: vitamin C;   Drug: placebo
Sponsors:   Radboud University;   ZonMw: The Netherlands Organisation for Health Research and Development
Completed

Fri, 26 Oct 2007 12:00:00 EDT

The Effect Of Hyaluronic Acid And Melatonin With Systemic Administration of Vitamin C On Implant Stability After Immediate Implant in Anterior Region

Condition:   Immediate Dental Implant
Interventions:   Procedure: immediate implant placement with melatonin hyaluronic acid vit C;   Procedure: immediate implant placement without melatonin hyaluronic acid vit C
Sponsor:   Cairo University
Not yet recruiting

Tue, 15 Jan 2019 12:00:00 EST

The Effect of Green Tea and Vitamin C on Skin Health

Condition:   Skin Cancer
Interventions:   Dietary Supplement: Green tea + vitamin C high dose;   Dietary Supplement: Placebo capsule
Sponsors:   University of Manchester;   University of Leeds;   University of Bradford
Completed

Tue, 15 Dec 2009 12:00:00 EST

ANti-Oxidant in Variant Angina (ANOVA) Trial

Condition:   Variant Angina
Interventions:   Drug: Vitamin C and Vitamin E;   Drug: Statin;   Drug: Standard medication for variant angina
Sponsor:   Seoul National University Hospital
Unknown status

Mon, 24 Jul 2017 12:00:00 EDT

Ascorbic Acid Levels in MDS, AML, and CMML Patients

Conditions:   Myelodysplastic Syndromes;   Acute Myeloid Leukemia;   Chronic Myelomonocytic Leukemia;   MDS;   AML;   CMML
Intervention:   Other: Peripheral blood collection
Sponsor:   Van Andel Research Institute
Completed

Wed, 16 May 2018 12:00:00 EDT

A Phase Ib/IIa Study Evaluating the Safety and Tolerability of Vitamin C in Patients With Intermediate or High Risk Myelodysplastic Syndrome With TET2 Mutations

Condition:   Myelodysplastic Syndromes
Intervention:   Drug: 50 gm CIVI/24 hours x 5 days every 4 week
Sponsors:   NYU Langone Health;   Perlmutter Cancer Center
Recruiting

Thu, 15 Feb 2018 12:00:00 EST

Comparison Between a 1L of Polyethylene Glycol+Ascorbic Acid as a Split Dose Bowel Preparation for Colonoscopy

Conditions:   Colon Adenoma;   Colonic Polyp
Interventions:   Drug: CleanViewAL;   Drug: SUPREP
Sponsor:   Seoul National University Hospital
Recruiting

Wed, 17 Feb 2021 12:00:00 EST

Automatic Chlorination and Child Health in Urban Bangladesh

Conditions:   Diarrhea;   Communicable Diseases
Interventions:   Device: Water chlorination by the Flogenic;   Device: Active control, vitamin C dosing into water
Sponsors:   Stanford University;   International Centre for Diarrhoeal Disease Research, Bangladesh
Completed

Tue, 17 Nov 2015 12:00:00 EST

Effects of Glucocorticoid Combined With Vitamin C and Vitamin B1 on Microcirculation in Severe Septic Shock

Condition:   Septic Shock
Interventions:   Drug: Glucocorticoid combination therapy;   Drug: Glucocorticoid
Sponsor:   Southeast University, China
Completed

Wed, 30 Jan 2019 12:00:00 EST

Targeting ER Stress in Vascular Dysfunction

Conditions:   Vasodilation;   Arterial Stiffness
Interventions:   Drug: Acetylcholine;   Drug: Sodium Nitroprusside;   Drug: Ascorbic Acid
Sponsor:   Colorado State University
Recruiting

Fri, 28 Jun 2019 12:00:00 EDT

VITAMIN E, C and ZINC IN PATIENTS WITH SKIN CANCER: INFLUENCE ON OXIDATIVE STRESS AND INFLAMMATORY STATE

Condition:   Skin Neoplasms
Intervention:   Dietary Supplement: Vitamin C, E and Zinc
Sponsor:   University of Campinas, Brazil
Completed

Thu, 25 Sep 2014 12:00:00 EDT

Obesity, Inflammation and Oxidative Stress

Conditions:   C-reactive Protein;   Inflammation;   Obesity;   Oxidative Stress
Interventions:   Dietary Supplement: Vitamin C (ascorbic acid);   Dietary Supplement: Placebo tablet
Sponsors:   University of California, Berkeley;   Kaiser Permanente
Completed

Wed, 09 Dec 2009 12:00:00 EST

Impact of Repeated Anthelmintic Treatment on the Risk of Malaria in Kenyan School Children

Conditions:   Intestinal Helminthiasis;   Ascariasis;   Hookworm;   Malaria
Interventions:   Drug: Albendazole;   Dietary Supplement: Vitamin C
Sponsors:   London School of Hygiene and Tropical Medicine;   European Union;   Wellcome Trust
Completed

Tue, 07 Aug 2012 12:00:00 EDT

Oral Sulfate Solution (SUPREP) Versus Polyethylene Glycol (PEG) Plus Ascorbic Acid

Condition:   Cathartic Colon
Interventions:   Drug: Oral sulfate solution (OSS);   Drug: 2-L PEG/Asc
Sponsors:   Bo-In Lee;   Pharmbio Korea Co., Ltd.
Completed

Wed, 04 May 2016 12:00:00 EDT

Melphalan, Arsenic Trioxide, and Ascorbic Acid in Treating Patients With Relapsed or Refractory Multiple Myeloma

Conditions:   Stage II Multiple Myeloma;   Stage III Multiple Myeloma;   Refractory Plasma Cell Neoplasm
Interventions:   Drug: arsenic trioxide;   Drug: ascorbic acid;   Drug: melphalan;   Procedure: chemosensitization/potentiation;   Procedure: chemotherapy
Sponsor:   Oncotherapeutics
Withdrawn

Fri, 11 Jun 2004 12:00:00 EDT

Thin Endometrium Undergoing Frozen-thawed Embryo Transfer

Condition:   Thin Endometrium
Interventions:   Drug: Tamoxifen and femoston;   Drug: Vitamin C and femoston
Sponsor:   Nanjing University
Recruiting

Tue, 03 Mar 2020 12:00:00 EST

Exploratory Study To Assess the Efficacy and Safety of a Triple Combination for Acute Pain Treatment in Patients With Temporomandibular Joint Disorders (TMJD).

Condition:   Temporomandibular Joint Disorders
Interventions:   Drug: Ibuprofen;   Drug: Magnesium;   Drug: Ascorbic Acid;   Drug: Placebo
Sponsors:   Spherium Biomed;   Universitat Internacional de Catalunya;   Hospital Odontològic UB;   Hospital Universitario La Fe;   Hospital Universitario Rey Juan Carlos
Completed

Wed, 11 Nov 2015 12:00:00 EST

Antioxidant in Patients HIV+ Supplemented With Microencapsulated of Red Pomegranate

Condition:   HIV Positive
Interventions:   Dietary Supplement: HIV+ MRPJ;   Dietary Supplement: HIV+ ascorbic acid
Sponsors:   Universidad Autónoma del Estado de Hidalgo;   National Council of Science and Technology, Mexico
Completed

Tue, 22 May 2018 12:00:00 EDT

Evaluation of Hydrocortisone, Vitamin C and Thiamine for the Treatment of Septic Shock

Conditions:   Septic Shock;   Critical Illness
Intervention:   Drug: Triple therapy group
Sponsor:   Hamad Medical Corporation
Unknown status

Thu, 21 Dec 2017 12:00:00 EST

The Study of Quadruple Therapy Zinc, Quercetin, Bromelain and Vitamin C on the Clinical Outcomes of Patients Infected With COVID-19

Condition:   Covid-19
Interventions:   Drug: Quercetin;   Dietary Supplement: bromelain;   Drug: Zinc;   Drug: Vitamin C
Sponsor:   Ministry of Health, Saudi Arabia
Recruiting

Mon, 13 Jul 2020 12:00:00 EDT

Targeting Central Pulsatile Hemodynamics in Chronic Kidney Disease

Condition:   Renal Insufficiency, Chronic
Interventions:   Drug: ISMN;   Dietary Supplement: Vitamin C
Sponsor:   University of Pennsylvania
Terminated

Tue, 07 Jun 2016 12:00:00 EDT

The Effectiveness of Montelukast on Atopic Dermatitis in Koreans

Condition:   Atopic Dermatitis
Interventions:   Drug: Montelukast first, then placebo;   Drug: Placebo first, then Montelukast
Sponsors:   Pyun BokYang;   Merck Sharp & Dohme Corp.
Completed

Mon, 18 May 2009 12:00:00 EDT

Oxaloacetate Supplementation for Emotional PMS

Condition:   Premenstrual Syndrome (PMS)
Interventions:   Dietary Supplement: Jubilance (100 mg Oxaloacetate/150 mg Ascorbic Acid);   Dietary Supplement: rice flour (Placebo)
Sponsor:   Terra Biological LLC
Completed

Thu, 26 Apr 2018 12:00:00 EDT

Antioxidant Supplementation in Pregnant Women With Low Antioxidant Status

Condition:   Preeclampsia
Intervention:   Drug: Vitamin C 1000mg and E 400IU
Sponsors:   Showa University;   Indonesia University
Completed

Tue, 17 Oct 2006 12:00:00 EDT

Evaluation and Treatment of Copper/Zinc Imbalance in Children With Autism

Conditions:   Autism;   Pervasive Developmental Disorder
Interventions:   Drug: oral zinc and vitamin C supplements;   Other: oral Placebo
Sponsors:   Milton S. Hershey Medical Center;   Thrasher Research Fund
Terminated

Mon, 15 May 2006 12:00:00 EDT

Oxidative Stress Expression and Metabolic Imbalance in Critically Ill Polytrauma Patients and the Implications of Antioxidant Therapy on Clinical Outcomes

Conditions:   Oxidative Stress;   Polytrauma
Intervention:   Drug: Vitamin C
Sponsors:   Romanian Society of Anesthesia and Intensive Care;   University of Medicine and Pharmacy "Victor Babes" Timisoara
Unknown status

Fri, 14 Jul 2017 12:00:00 EDT

2L Oral Bi-PegLyte Versus 2L Oral MoviPrep Regimen for Outpatient Colonic Preparation

Condition:   Colonoscopy
Interventions:   Drug: Polyethylene Glycol (PEG) and 15 mg Bisacodyl;   Drug: Polyethylene Glycol (PEG) + ascorbic acid
Sponsor:   University of British Columbia
Completed

Fri, 31 May 2013 12:00:00 EDT

An Efficacy and Safety Study of Theraflu Night Powder as Oral Solution for Cold and Flu

Condition:   Infections, Respiratory Tract
Intervention:   Drug: Paracetamol, phenylephrine HCl, pheniramine maleate, and vitamin C
Sponsor:   GlaxoSmithKline
Withdrawn

Wed, 06 Apr 2016 12:00:00 EDT

Pilot Study on the Use of Hydrocortisone, Vitamin c and Tiamine in Patient With Sepsis and Septic Shock

Conditions:   Sepsis;   Septic Shock
Interventions:   Drug: red blood cells transfusion, tranexamic acid (TXA) and fibrinogen concentrate;   Drug: on crystalloid fluid and Tranexamic acid
Sponsor:   Cristina Martinez
Unknown status

Tue, 01 Oct 2019 12:00:00 EDT

Impact of Low Fiber Diet on Colonic Cleansing Quality (DIETPREP)

Condition:   Cleansing Quality of the Colon
Interventions:   Other: One-day Low fiber diet;   Other: Three-day low fiber diet;   Drug: Polyethylene Glycol plus ascorbic acid
Sponsor:   Hospital Universitario de Canarias
Completed

Fri, 11 Aug 2017 12:00:00 EDT

The Effectiveness of Pleuran in Treatment of Acute Gastroenteritis in Children

Condition:   Diarrhoea;Acute
Interventions:   Dietary Supplement: Imunoglukan PH4;   Dietary Supplement: Placebo (vitamin C syrup)
Sponsors:   Medical University of Warsaw;   Nutricia Foundation;   PLEURAN s.r.o.
Recruiting

Mon, 17 Jun 2019 12:00:00 EDT

The Relationship of Hemoglobin A1c and Diabetic Wound Healing

Conditions:   Diabetes, Type 1;   Diabetes, Type 2;   Foot Ulcer, Diabetic
Interventions:   Drug: Bacitracin;   Drug: AmeriGel®;   Dietary Supplement: Vitamin C
Sponsor:   Susan Hassenbein
Terminated

Mon, 09 May 2011 12:00:00 EDT

Antioxidants Combined With Cryotherapy on Inflammatory Response After Resistance Exercise in Untrained Volunteers

Conditions:   Inflammation;   Oxidative Stress;   Pain
Interventions:   Other: Cryotherapy;   Other: Vitamins C and E;   Other: Vitamins C and E associated with cryotherapy;   Other: Placebo
Sponsor:   Universidade Federal de Santa Maria
Completed

Thu, 15 Sep 2016 12:00:00 EDT

Percutaneous Pin Removal in Children - is Analgesia Necessary?

Condition:   Elbow Fracture
Interventions:   Drug: Acetaminophen;   Drug: Ibuprofen;   Other: Vitamin C
Sponsor:   KK Women's and Children's Hospital
Completed

Tue, 17 Sep 2013 12:00:00 EDT

Determination of a Dose-dependent Effect of GOS on Iron Absorption, and Addition of Vitamin C

Condition:   Iron-deficiency
Interventions:   Dietary Supplement: ferrous fumarate;   Dietary Supplement: ferrous sulphate;   Dietary Supplement: ferric pyrophosphate;   Dietary Supplement: ferrous fumarate + 3.5 g GOS;   Dietary Supplement: ferrous fumarate + 7 g GOS;   Dietary Supplement: ferrous sulphate + 15 g GOS;   Dietary Supplement: ferrous fumarate + Vitamin C;   Dietary Supplement: ferric pyrophosphate + 15 g GOS;   Dietary Supplement: ferrous fumarate + 7 g GOS + Vitamin C
Sponsors:   Isabelle Herter-Aeberli;   Burgerstein Vitamine
Completed

Mon, 03 Dec 2018 12:00:00 EST

The Effects of Natural Extracts Supplementation on NASH Patients

Condition:   NAFLD
Interventions:   Dietary Supplement: Choline - Vitamin C, E and Ampelopsis Grossedentata natural extracts;   Other: Placebo
Sponsors:   University of Athens;   Laikο General Hospital, Athens
Not yet recruiting

Wed, 22 Sep 2021 12:00:00 EDT

Delivery of Inhibitors of Lysyl Oxidase (LysoLox) on Serial Angioplasty and Time to Restenosis

Condition:   Arteriovenous Fistula Occlusion
Interventions:   Drug: Placebo;   Drug: Ascorbic Acid;   Drug: Cuprimine Oral Product
Sponsors:   Southeast Renal Research Institute;   Dialysis Clinic, Inc.
Unknown status

Tue, 11 Apr 2017 12:00:00 EDT

Effect of Vitamin E on Pediatric Nonalcoholic Fatty Liver Disease (NAFLD)

Conditions:   Inflammation;   Fibrosis;   Insulin Resistance
Interventions:   Dietary Supplement: Vitamin treatment (alpha tocopherol plus ascorbic acid);   Dietary Supplement: Placebo
Sponsor:   Bambino Gesù Hospital and Research Institute
Completed

Wed, 09 Apr 2008 12:00:00 EDT

Coenzyme Q10 Plus NADH Supplementation in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis

Condition:   Chronic Fatigue Syndrome
Interventions:   Dietary Supplement: Coenzyme Q10 plus NADH;   Dietary Supplement: phosphoserine plus vitamin C
Sponsors:   Hospital Universitari Vall d'Hebron Research Institute;   VITAE NATURAL NUTRITION, S.L.
Unknown status

Wed, 14 Jun 2017 12:00:00 EDT

Decitabine, Arsenic Trioxide and Ascorbic Acid for Myelodysplastic Syndromes and Acute Myeloid Leukemia

Condition:   Myelodysplastic Syndromes and Leukemia, Myeloid, Acute
Interventions:   Drug: Arsenic Trioxide;   Drug: Decitabine
Sponsors:   Washington University School of Medicine;   Cephalon
Completed

Mon, 05 May 2008 12:00:00 EDT

Efficacy of Vitamin C on AKI Outcomes in Critically Ill Cirrhotics With Multidrug-resistant Bacterial Infections.

Condition:   Liver Cirrhosis
Interventions:   Drug: Vit C;   Drug: Standard medical Treatment
Sponsor:   Institute of Liver and Biliary Sciences, India
Not yet recruiting

Fri, 31 Jul 2020 12:00:00 EDT

Tetrahydrobiopterin in Patients With Chronic Kidney Disease (CKD) and Albuminuria

Conditions:   Kidney Disease;   Albuminuria
Interventions:   Drug: 6R BH4;   Dietary Supplement: Vitamin C
Sponsors:   University of Michigan;   BioMarin Pharmaceutical
Completed

Thu, 28 Feb 2008 12:00:00 EST

A 4-month Intervention of Antioxidant Supplementation in Overweight Children

Condition:   Metabolic Syndrome
Intervention:   Dietary Supplement: Vitamin C Vitamin E Selenvital all from Burgerstein Vitamine
Sponsor:   Swiss Federal Institute of Technology
Completed

Wed, 16 Mar 2011 12:00:00 EDT

Iron Bioavailability From Encapsulated Ferrous Sulphate

Condition:   Iron Deficiency
Interventions:   Dietary Supplement: non-encapsulated FeSO4;   Dietary Supplement: encapsulated FeSO4, before cooking;   Dietary Supplement: encapsulated FeSO4, after cooking;   Dietary Supplement: non-encapsulated FeSO4 + ascorbic acid;   Dietary Supplement: encapsulated FeSO4 + ascorbic acid, before cooking;   Dietary Supplement: encapsulated FeSO4 + ascorbic acid, after cooking
Sponsor:   Swiss Federal Institute of Technology
Completed

Mon, 02 Feb 2015 12:00:00 EST

The Relation Between Serum Ascorbic Acid Concentration and Preterm Premature Rupture of Membranes

Condition:   Preterm Premature Rupture of Membranes
Intervention:  
Sponsor:   Ain Shams Maternity Hospital
Unknown status

Fri, 18 Dec 2015 12:00:00 EST

Pharmacological Ascorbate for Lung Cancer

Condition:   Carcinoma, Non-Small-Cell Lung
Interventions:   Drug: Paclitaxel;   Drug: Carboplatin;   Drug: Ascorbic Acid
Sponsors:   Joseph J. Cullen, MD, FACS;   National Cancer Institute (NCI);   National Institutes of Health (NIH);   Holden Comprehensive Cancer Center;   McGuff Pharmaceuticals, Inc.
Recruiting

Fri, 17 Apr 2015 12:00:00 EDT

Iron & Vitamin C Study

Condition:   Spinal Cord Injury
Intervention:  
Sponsor:   US Department of Veterans Affairs
Completed

Wed, 15 Apr 2009 12:00:00 EDT

Treatment on HBeAg Positive or HBeAg Negative in Chronic Hepatitis B

Condition:   CHRONIC HEPATITIS B
Intervention:   Drug: CTH Chronic Hepatitis B
Sponsor:   Triệu, Nguyễn Thị, M.D.
Approved for marketing

Fri, 10 Sep 2010 12:00:00 EDT

Arsenic Trioxide, Ascorbic Acid, Dexamethasone, and Thalidomide in Treating Patients With Multiple Myeloma

Conditions:   Stage I Multiple Myeloma;   Stage II Multiple Myeloma;   Stage III Multiple Myeloma;   Refractory Plasma Cell Neoplasm
Interventions:   Drug: arsenic trioxide;   Drug: ascorbic acid;   Drug: dexamethasone;   Drug: thalidomide;   Procedure: anti-cytokine therapy;   Procedure: antiangiogenesis therapy;   Procedure: biological therapy;   Procedure: chemotherapy;   Procedure: drug resistance inhibition;   Procedure: growth factor antagonist therapy;   Procedure: non-specific immune-modulator therapy
Sponsor:   The Cleveland Clinic
Withdrawn

Fri, 03 Jun 2005 12:00:00 EDT

Impact of Pinaverium Bromide on Bile Duct and Pancreatic Duct Cannulation During Endoscopic Retrograde Cholangiopancreatography

Condition:   Bile Duct Diseases
Interventions:   Dietary Supplement: pinaverium bromide;   Dietary Supplement: Vitamin C
Sponsor:   Changhai Hospital
Unknown status

Mon, 29 Aug 2016 12:00:00 EDT

The Comparative Study Between Bowel Preparation Method

Condition:   Colonoscopy
Intervention:   Drug: Colonoscopy after bowel cleansing
Sponsor:   Inje University
Completed

Thu, 17 Oct 2013 12:00:00 EDT

Plasmatic L-AScorbic Acid in MYelodyplastic Syndroms and Controls

Conditions:   Myelodysplastic Syndrome;   Secondary Acute Myeloid Leukemia
Interventions:   Other: Samples;   Other: Quality of life questionnaire
Sponsors:   University Hospital, Tours;   Tours Autogreffe;   Novartis
Completed

Wed, 22 Jun 2016 12:00:00 EDT

Vitamin Deficiency and Blood Pressure in Hospitalized Jewish General Hospital (JGH) Patients

Conditions:   Vitamin C Deficiency;   Vitamin D Deficiency
Interventions:   Dietary Supplement: Vitamin D;   Dietary Supplement: Vitamin C
Sponsor:   Jewish General Hospital
Completed

Tue, 16 Jun 2009 12:00:00 EDT

Effect of Vitamin C, D and Zinc Supplementation on the Immune and Inflammatory Process in Type 2 Diabetic Subjects

Condition:   Diabetes Mellitus, Type 2
Interventions:   Dietary Supplement: Vitamin Supplement;   Other: Placebo
Sponsor:   Universidad Autonoma del Estado de Mexico
Unknown status

Thu, 08 Nov 2018 12:00:00 EST

4-step ASCOT in POI Women to Promote Follicular Rescue

Condition:   Premature Ovarian Insufficiency
Interventions:   Drug: G-CSF treatment for Bone marrow derived stem cell Mobilization;   Procedure: Platelet Rich Plasma ovarian injection
Sponsors:   Fundación IVI;   Instituto Valenciano de Infertilidad, IVI VALENCIA;   IVI Madrid;   Hospital Universitario La Fe
Recruiting

Fri, 17 Jul 2020 12:00:00 EDT

Echinacea Junior vs Vitamin C in Children 4-12 Years Old

Condition:   Respiratory Tract Infection Viral
Intervention:   Drug: Echinaforce
Sponsor:   A. Vogel AG
Completed

Wed, 23 Nov 2016 12:00:00 EST

International ALLIANCE Study of Therapies to Prevent Progression of COVID-19

Condition:   COVID19
Interventions:   Dietary Supplement: Vitamin C;   Drug: Hydroxychloroquine;   Drug: Azithromycin;   Dietary Supplement: Zinc Citrate;   Dietary Supplement: Vitamin D3;   Dietary Supplement: Vitamin B12
Sponsor:   National Institute of Integrative Medicine, Australia
Recruiting

Wed, 20 May 2020 12:00:00 EDT

Clinical Evaluation of a New Reduced Volume Bowel Preparation

Condition:   Colonoscopy
Intervention:   Drug: macrogol3350 NA sulphate NACL KCL ascorbic acid NA ascorbate
Sponsor:   Norgine
Completed

Wed, 03 May 2006 12:00:00 EDT

Intravenous Iron Isomaltoside Versus Oral Iron Supplementation for Treatment of Iron Deficiency in Pregnancy.

Condition:   Iron Deficiency Anemia of Pregnancy
Interventions:   Drug: Iron Isomaltoside 1000;   Drug: ferrous fumarate with ascorbic acid
Sponsor:   Pharmacosmos A/S
Completed

Thu, 15 Jun 2017 12:00:00 EDT

Cross-over Double-blind Intervention to Investigate the Effects of Defined Antioxidant-containing Drinks on Time Course of Antioxidant Capacity

Condition:   The Impact of Vitamin c and Epicatechin Upon Antioxidant Capactity
Interventions:   Dietary Supplement: Placebo;   Dietary Supplement: Vitamin C;   Dietary Supplement: epicatechin
Sponsors:   Newcastle University;   Linkoeping University
Unknown status

Tue, 13 Sep 2016 12:00:00 EDT

RCT of Antioxidant Therapy to Prevent Preeclampsia in Brazil

Conditions:   Preeclampsia;   Eclampsia;   HELLP Syndrome;   Pregnancy
Intervention:   Drug: Vitamin C and E
Sponsors:   NICHD Global Network for Women's and Children's Health;   Global Network for Women's and Children's Health Research;   Bill and Melinda Gates Foundation;   Fogarty International Center of the National Institute of Health;   National Center for Complementary and Integrative Health (NCCIH);   National Institute of Dental and Craniofacial Research (NIDCR);   National Cancer Institute (NCI);   RTI International;   University of Cincinnati;   Universidade Federal de Pernambuco;   Feculdade de Medicina da Universidade de Sao Paulo - Brasil;   Faculdade de Medicina de Botucatu, UNESP, Botucatu, Brasil;   University of Campinas, Brazil;   Hospital de Clinicas de Porto Alegre
Completed

Thu, 18 Nov 2004 12:00:00 EST

A Study of Hydroxychloroquine, Vitamin C, Vitamin D, and Zinc for the Prevention of COVID-19 Infection

Conditions:   COVID-19;   Coronavirus Infection;   Sars-CoV2;   Corona Virus Infection;   COVID;   Coronavirus;   Coronavirus-19;   Coronavirus 19
Interventions:   Drug: Hydroxychloroquine;   Dietary Supplement: Vitamin C;   Dietary Supplement: Vitamin D;   Dietary Supplement: Zinc
Sponsors:   ProgenaBiome;   DSCS CRO
Recruiting

Mon, 06 Apr 2020 12:00:00 EDT

Vitamins C and Vitamin E and Cardiovascular Risk

Condition:   Diabetes
Interventions:   Dietary Supplement: Study Arm A;   Dietary Supplement: Study Arm B;   Dietary Supplement: Study Arm C;   Dietary Supplement: Study Arm D
Sponsors:   University of New Mexico;   American Diabetes Association
Completed

Thu, 10 Aug 2006 12:00:00 EDT

Autologous Bone Marrow Stem Cell Ovarian Transplantation to Restore Ovarian Function in Premature Ovarian Failure

Condition:   Premature Ovarian Failure (POF)
Interventions:   Drug: G-CSF;   Combination Product: ASCOT
Sponsor:   Instituto de Investigacion Sanitaria La Fe
Not yet recruiting

Thu, 24 May 2018 12:00:00 EDT

Reversing Glucose and Lipid-mediated Vascular Dysfunction

Conditions:   Blood Pressure;   Hypertension
Interventions:   Drug: Dextrose 20 % in 500 ML Injection;   Drug: Intralipid;   Drug: Saline;   Drug: Ascorbic acid
Sponsor:   University of Kansas Medical Center
Not yet recruiting

Mon, 05 Apr 2021 12:00:00 EDT

Treatment of Newly Diagnosed Ovarian Cancer With Antioxidants

Condition:   Ovarian Cancer
Interventions:   Dietary Supplement: Oral Ascorbic Acid;   Drug: Paclitaxel;   Drug: Carboplatin;   Drug: Sodium Ascorbate;   Dietary Supplement: Oral Mixed natural Carotenoids with Vitamin A;   Dietary Supplement: Vitamin E
Sponsors:   Jeanne Drisko, MD, CNS, FACN;   Cancer Treatment Research Foundation;   University of Kansas Medical Center
Completed

Wed, 28 Sep 2005 12:00:00 EDT

Chronic Mountain Sickness, Systemic Vascular Function

Conditions:   Mountain Sickness;   Chronic
Interventions:   Dietary Supplement: Vitamin C and E;   Dietary Supplement: Placebo
Sponsors:   University of Lausanne Hospitals;   Instituto Boliviano de Biologia de Altura;   Universitad Major de S. Andres, La Paz, Bolivia
Active, not recruiting

Tue, 17 Aug 2010 12:00:00 EDT

A Phase III Trial to Assess the Efficacy, Acceptability and Safety of Moviprep® Versus a 4L PEG+E Standard Solution

Condition:   Colonoscopy
Interventions:   Drug: Macrogol3350 NA sulphate NACl KCl ascorbic acid NA ascorbate;   Drug: Macrogol3350 Na sulphate Na bicarbonate NaCl KCl
Sponsor:   Norgine
Completed

Wed, 18 Oct 2006 12:00:00 EDT

Local Antioxidant Therapy Vasoconstriction Effects in Different Races

Conditions:   Cardiovascular Diseases;   Cardiovascular Risk Factor;   Vasoconstriction
Interventions:   Drug: Control (Norepinephrine);   Drug: Norepinephrine + Ascorbic Acid;   Drug: Norepinephrine + L-NAME;   Drug: Norepinephrine + L-NAME + Ascorbic Acid
Sponsor:   The University of Texas at Arlington
Recruiting

Tue, 25 Sep 2018 12:00:00 EDT

The Effects of Vitamin B-6 Status on Homocysteine, Oxidative Stress, One-carbon Metabolism and Methylation: Cross-section, Case-control, Intervention and Follow-up Studies in Colorectal Cancer

Condition:   Colorectal Cancer
Interventions:   Dietary Supplement: Vitamin C;   Dietary Supplement: Vitamin B6;   Dietary Supplement: Folic acid;   Dietary Supplement: Vitamin B6 plus folic acid
Sponsor:   Taichung Veterans General Hospital
Unknown status

Wed, 31 Aug 2011 12:00:00 EDT

MOVIPREP® Versus NaP Pivotal Phase III Study

Condition:   Colonoscopy
Interventions:   Drug: macrogol3350 NA sulphate NACL KCL ascorbic acid NA ascorbate;   Drug: Sodium Phosphate Solution
Sponsor:   Norgine
Completed

Thu, 04 May 2006 12:00:00 EDT

Chewing Gum Containing Vitamin-c to Treat Emesis Gravidarum

Conditions:   Hyperemesis Gravidarum;   Nausea Gravidarum;   Vitamin C Deficiency
Interventions:   Dietary Supplement: Pregnan-C-Gum(R) chewing gum;   Dietary Supplement: Placebo chewing gum
Sponsor:   Medical University of Vienna
Recruiting

Wed, 26 Feb 2020 12:00:00 EST

Acetaminophen and Ascorbate in Sepsis: Targeted Therapy to Enhance Recovery

Conditions:   Acute Respiratory Distress Syndrome;   Critical Illness;   Respiratory Failure;   Sepsis
Interventions:   Drug: Intravenous Acetaminophen (room temperature);   Drug: Intravenous Vitamin C (refrigerated);   Drug: 5% Dextrose (room temperature);   Drug: 5% Dextrose refrigerated
Sponsor:   Massachusetts General Hospital
Not yet recruiting

Mon, 02 Mar 2020 12:00:00 EST

An Efficacy and Safety Study of Theraflu Day Powder as Oral Solution for Cold and Flu

Condition:   Infections, Respiratory Tract
Intervention:   Drug: Paracetamol, phenylephrine HCl, and vitamin C
Sponsor:   GlaxoSmithKline
Withdrawn

Tue, 09 Feb 2016 12:00:00 EST

A Phase 2 Study Adding Ascorbate to Chemotherapy and Radiation Therapy for NSCLC

Conditions:   Carcinoma, Non-Small-Cell Lung;   Non-Small Cell Lung Cancer;   Nonsmall Cell Lung Cancer;   Non-Small-Cell Lung Carcinoma;   NSCLC
Interventions:   Drug: Radiation Therapy;   Drug: Paclitaxel;   Drug: Carboplatin;   Drug: Ascorbic Acid
Sponsors:   Joseph J. Cullen, MD, FACS;   National Institutes of Health (NIH);   National Cancer Institute (NCI);   Holden Comprehensive Cancer Center
Recruiting

Mon, 19 Sep 2016 12:00:00 EDT

Iron Absorption From Complementary Food Fortificants (CFFs) and Acceptability of CFFs by Beninese Children

Conditions:   Iron Deficiency;   Anemia
Interventions:   Other: NaFeEDTA;   Other: Phytase;   Other: Vitamin C
Sponsors:   Swiss Federal Institute of Technology;   Université d'Abomey-Calavi
Completed

Wed, 23 Mar 2011 12:00:00 EDT

Effect of Vitamin D Supplementation on Hemoglobin A1c in Patients With Uncontrolled Type 2 Diabetes Mellitus

Condition:   Type 2 Diabetes Mellitus
Interventions:   Dietary Supplement: Vitamin D3 2000 international units daily;   Dietary Supplement: Vitamin C 500mg daily
Sponsor:   ProMedica Health System
Completed

Mon, 28 Sep 2009 12:00:00 EDT

Clinical Experimentation With Tenofovir Disoproxyl Fumarate and Emtricitabine for COVID-19

Condition:   Covid19
Interventions:   Drug: Vitamin C 500 MG Oral Tablet;   Drug: Tenofovir disoproxyl fumarate 300 MG Oral Tablet;   Drug: Tenofovir disoproxyl fumarate 300 MG plus emtricitabine 200 MG Oral Tablet
Sponsors:   Universidade Federal do Ceara;   Conselho Nacional de Desenvolvimento Científico e Tecnológico;   São José Hospital for Infectious Diseases - HSJ;   Central Laboratory of Public Health of Ceará - Lacen-CE
Recruiting

Fri, 15 Jan 2021 12:00:00 EST

Antioxidant Bioavailability

Condition:   Pharmacokinetics
Interventions:   Dietary Supplement: Liposomal vitamin C, 1 gram;   Dietary Supplement: Liposomal vitamin C, 2 grams;   Dietary Supplement: Liposomal vitamin C, 5 grams;   Dietary Supplement: Placebo
Sponsor:   Natural Immune Systems Inc
Recruiting

Thu, 09 Jul 2020 12:00:00 EDT

Changing Over Time of Ascorbic Acid After Chemotherapy

Conditions:   Leukemia (Both ALL and AML);   Cancer of Lung;   Myeloma
Intervention:   Other: blood withdrawn
Sponsor:   Maastricht University Medical Center
Active, not recruiting

Thu, 13 Oct 2016 12:00:00 EDT

Micronutrients to Prevent Noise-induced Hearing Loss

Condition:   Noise-Induced Hearing Loss
Interventions:   Drug: beta-carotene, vitamins C and E, magnesium;   Other: Placebo
Sponsors:   University of Michigan;   National Institute on Deafness and Other Communication Disorders (NIDCD);   University of Florida;   Southern Illinois University;   Hearing Health Science, Inc.
Completed

Mon, 15 Dec 2008 12:00:00 EST

Effect of Anti-inflammatory and Anti-microbial Co-supplementations in Traumatic ICU Patients at High Risk of Sepsis

Conditions:   Major Trauma;   Sepsis
Interventions:   Drug: oral lactobacillus probiotics plus intramuscular cholecalciferol;   Drug: intravenous vitamin C plus thiamine
Sponsor:   Mansoura University
Recruiting

Thu, 02 Jan 2020 12:00:00 EST

Primary Prevention Trial of the Health Effects of Antioxidant Vitamins and Minerals.

Condition:   Healthy
Intervention:   Behavioral: ascorbic acid, vitamin E, beta carotene, selenium, zinc
Sponsors:   Institut National de la Santé Et de la Recherche Médicale, France;   French private agencies
Completed

Fri, 06 Jan 2006 12:00:00 EST

Treatment of Pulmonary Fibrosis Due to COVID-19 With Fuzheng Huayu

Condition:   Pulmonary Fibrosis Due to COVID-19
Interventions:   Drug: Fuzheng Huayu Tablet;   Drug: Vitamin C tablets;   Other: Placebo;   Other: respiratory function rehabilitation training
Sponsors:   ShuGuang Hospital;   Hubei Hospital of Traditional Chinese Medicine;   Jingmen No.1 People's Hospital;   Tongji Hospital;   Wenzhou Central Hospital;   Wuhan No.1 Hospital;   Wuhan Union Hospital, China;   Wuhan Third Hospital
Recruiting

Fri, 21 Feb 2020 12:00:00 EST

Neural Mechanism of Cortisol Awakening Response Suppression Effect on Human High-order and Social Cognitions

Condition:   Healthy
Interventions:   Drug: Dexamethasone;   Drug: Vitamin C
Sponsors:   qinshaozheng;   Chinese Academy of Sciences;   Xuanwu Hospital, Beijing
Completed

Tue, 14 Jun 2016 12:00:00 EDT

The Effect of Continuous Sipping of a Glucose Solution on Markers of Oxidation in Men and Women

Conditions:   Cardiovascular Disease;   Diabetes
Interventions:   Dietary Supplement: glucose bolus;   Dietary Supplement: Glucose sipping;   Dietary Supplement: Glucose bolus plus 1g vitamin C;   Dietary Supplement: Glucose sipping plus 1g vitamin C
Sponsors:   University of Toronto;   Canadian Institutes of Health Research (CIHR)
Completed

Tue, 27 Sep 2011 12:00:00 EDT

Effects of Polyphenol Containing Antioxidants on Oxidative Stress in Diabetic Patients

Condition:   Type 2 Diabetes
Intervention:   Dietary Supplement: PomGT (500 mg pomegranate extracts, 300 mg green tea and 60mg vitamin C)
Sponsor:   Yeditepe University Hospital
Unknown status

Thu, 22 May 2008 12:00:00 EDT

Intravenous Vitamin C in the Treatment of Viral Infection, Especially in the Treatment of Shingles

Conditions:   Virus Diseases;   Herpes Zoster
Intervention:  
Sponsors:   Pascoe Pharmazeutische Praeparate GmbH;   Dr. Loges & Co. GmbH
Completed

Wed, 17 Jun 2009 12:00:00 EDT

High Dose Ascorbate With Preoperative Radiation in Patients With Locally Advanced Soft Tissue Sarcomas

Condition:   Soft Tissue Sarcoma
Intervention:   Drug: Ascorbate
Sponsors:   Varun Monga, MD;   University of Iowa
Recruiting

Thu, 26 Apr 2018 12:00:00 EDT

Vitamin C Supplementation to Pregnant Smokers: Follow-up of 2 Randomized Trials Plus Changes in DNA Methylation

Conditions:   Asthma;   Wheezing;   In Utero Nicotine;   Pulmonary Function
Intervention:   Other: No current intervention
Sponsors:   Oregon Health and Science University;   Indiana University;   National Institutes of Health (NIH)
Recruiting

Sun, 02 Jul 2017 12:00:00 EDT

Effects of Oral Supplementation of Arginine, Zinc and Vitamin C on Collagen Synthesis in Inguinal Hernia Patients

Condition:   Inguinal Hernia
Interventions:   Dietary Supplement: Intervention;   Dietary Supplement: Control
Sponsor:   Lars Nannestad Jorgensen
Completed

Tue, 18 Jul 2017 12:00:00 EDT

Changes of Serum Electrolytes During Bowel Prep With PEG 3350 + Ascorbic Acid - a Prospective Study

Condition:   Colonoscopy
Intervention:  
Sponsor:   Klinik Bogenhausen
Completed

Fri, 26 Apr 2013 12:00:00 EDT

COMBOPROFEN for Treatment of Muscular Pain Associated With Delayed Onset Muscle Soreness (DOMS)

Condition:   Delayed Onset Muscle Soreness, DOMS
Interventions:   Drug: Comboprofen;   Drug: Placebo;   Drug: Ibuprofen;   Drug: Magnesium;   Drug: Vitamin C
Sponsors:   Spherium Biomed;   Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Completed

Fri, 21 Jul 2017 12:00:00 EDT

Impact of NOS, COX, and ROS Inhibition on Cerebral Blood Flow Regulation

Conditions:   Hypoxia;   Hypercapnia
Interventions:   Drug: L-NMMA;   Drug: Ketorolac;   Drug: Ascorbic Acid;   Procedure: Intravenous Catheter;   Procedure: Transcranial Doppler Ultrasound
Sponsor:   University of Wisconsin, Madison
Withdrawn

Tue, 28 Feb 2017 12:00:00 EST

Comparison of 2L NRL994 With NaP Preparation in Colon Cleansing Prior to Colonoscopies for Colon Tumor Screening

Condition:   Colonoscopy
Interventions:   Drug: Macrogol 3350 Na sulphate NaCl KCl Ascorbic Acid Na Ascorbate;   Drug: Sodium Phosphate solution (NaP)
Sponsor:   Norgine
Completed

Fri, 26 Jan 2007 12:00:00 EST

Changes of Biomarkers in Response to Training and Antioxidant Treatment

Conditions:   Obesity;   Type 2 Diabetes
Interventions:   Dietary Supplement: Vitamin C, Vitamin E;   Dietary Supplement: Antioxidant treatment
Sponsors:   University of Leipzig;   University of Jena
Completed

Wed, 19 Mar 2008 12:00:00 EDT

VitamIn and oXygen Interventions and Cardiovascular Events

Condition:   Postoperative Cardiac Complication
Interventions:   Drug: Oxygen;   Drug: Antioxidants
Sponsor:   University Hospital Bispebjerg and Frederiksberg
Completed

Wed, 11 Apr 2018 12:00:00 EDT

Oxidative Stress Links Aging, Activity, and Mobility Limitation

Condition:   Aging
Intervention:   Dietary Supplement: Vitamins C, E, and alpha lipoic acid
Sponsors:   VA Office of Research and Development;   University of Utah
Terminated

Fri, 06 Aug 2010 12:00:00 EDT

Systemic Markers of Collagen Metabolism and Vitamin C in Smokers and Non-Smokers With Pelvic Organ Prolapse

Condition:   Pelvic Organ Prolapse
Intervention:   Other: Blood draw for the study participants
Sponsor:   TriHealth Inc.
Completed

Thu, 08 Mar 2012 12:00:00 EST

Protect and Improve Cluster of Differentiation 4 (CD4) Cells and B Cells Lymphocytes

Conditions:   HIV-1-infection;   AIDS
Interventions:   Drug: Ahah Drug;   Device: Ahah Placebo
Sponsor:   Trieu, Nguyen Thi, M.D.
Completed

Thu, 25 Feb 2021 12:00:00 EST

PEG-Electrolyte Solution (FORTRANS®) With Mentholyptus Drops (Halls®) Versus Reduced Volume Ascorbic Acid Supplemented PEG-Electrolyte (MoviPrep®) in Colonoscopy Preparation

Condition:   Bowel Cleansing in Preparation for Colonoscopy
Intervention:   Other: preparation cleaning solution
Sponsor:   American University of Beirut Medical Center
Completed

Mon, 11 Feb 2013 12:00:00 EST

The Effect of a Local Injection of a Platelet Concentrate on Infection and Healing of Surgical Wounds

Condition:   Wound Infection and Wound Healing
Interventions:   Other: Leucocyte - Platelet rich Plasma;   Dietary Supplement: Vitamin C;   Dietary Supplement: Zinc;   Dietary Supplement: L-Arginine
Sponsors:   Jens Rikardt Andersen;   Rigshospitalet, Denmark
Unknown status

Tue, 16 Aug 2016 12:00:00 EDT

EXPLORATORY ASSESSMENT OF THE EFFECTS OF CYCLO 3 ® FORT (Ruscus Extract, Hesperidin Methyl Chalcone, Ascorbic Acid) OR MICRONISED PURIFIED FLAVONOID FRACTION ON VASCULAR PARAMETERS AND BIOMARKERS IN WOMEN SUFFERING FROM CHRONIC VENOUS DISEASE (CEAP C2 OR C3), OVER 8 WEEKS

Condition:   Venous Disease Classification (CEAP): C2 or C3
Interventions:   Drug: CYCLO 3 ® FORT;   Drug: MPFF;   Drug: placebo CYCLO 3 ® FORT;   Drug: placebo MPFF
Sponsors:   Pierre Fabre Medicament;   Eurotrials Brasil Consultores Cientificos Ltda
Withdrawn

Tue, 20 Sep 2016 12:00:00 EDT

Frontline Oral Arsenic Trioxide for APL

Condition:   Acute Promyelocytic Leukemia
Intervention:   Drug: Oral Arsenic Trioxide Formulation
Sponsor:   The University of Hong Kong
Recruiting

Tue, 29 Dec 2020 12:00:00 EST

Oral Pregabalin Premedication for Postoperative Pain Relief

Condition:   Gynecologic Disease
Interventions:   Drug: placebo capsule (vitamin c);   Drug: Group pregabalin 150;   Drug: Group pregabalin 300
Sponsor:   Zagazig University
Recruiting

Wed, 13 Jan 2021 12:00:00 EST

Clinical Application of Methylene Blue for Treatment of Covid-19 Patients

Condition:   Covid-19
Intervention:   Drug: MCN (Methylene blue, vitamin C, N-acetyl cysteine)
Sponsor:   Mashhad University of Medical Sciences
Recruiting

Thu, 30 Apr 2020 12:00:00 EDT

Safety and Immunogenicity of Peru-15-pCTB in Healthy Adult Subjects

Condition:   Gastroenteritis Escherichia Coli
Interventions:   Drug: Ciprofloxacin;   Biological: Peru-15-pCTB;   Other: Sodium bicarbonate/Ascorbic Acid/Aspartame Buffer
Sponsor:   National Institute of Allergy and Infectious Diseases (NIAID)
Completed

Mon, 07 Apr 2008 12:00:00 EDT

Comparison of Low Volume PEG-Asc and Lower Volume PEG-Asc With Bisacodyl

Conditions:   Bowel Disease;   Colon Adenoma
Interventions:   Drug: Polyethylene Glycols;   Drug: Bisacodyl
Sponsor:   Korea University Anam Hospital
Completed

Fri, 02 Dec 2016 12:00:00 EST

A Comparison of Solid and Soluble Forms of Cold and Influenza Remedies

Conditions:   Influenza;   Common Cold
Interventions:   Drug: Paracetamol;   Drug: Phenylephrine;   Drug: Ascorbic Acid
Sponsor:   GlaxoSmithKline
Completed

Mon, 11 Apr 2011 12:00:00 EDT

Vitamin D, Omega-3, and Combination Vitamins B, C and Zinc Supplementation for the Treatment and Prevention of COVID-19

Condition:   Covid19
Interventions:   Dietary Supplement: Vitamin D;   Dietary Supplement: Omega DHA / EPA;   Dietary Supplement: Vitamin C, Vitamin B complex and Zinc Acetate
Sponsors:   Hospital de la Soledad;   Microclinic International
Active, not recruiting

Fri, 02 Apr 2021 12:00:00 EDT

Phophate Lowering Trial

Conditions:   Chronic Kidney Disease;   Cardiovascular Disease
Interventions:   Drug: Lanthanum carbonate;   Drug: placebo;   Drug: Ascorbic Acid;   Drug: Nitroglycerin;   Procedure: Flow-mediated dilation measurement;   Procedure: Aortic pulse-wave velocity;   Procedure: Endothelial cell collection
Sponsor:   VA Office of Research and Development
Active, not recruiting

Wed, 06 Aug 2014 12:00:00 EDT

Comparison Between Coolprep and Picolyte for Bowel Cleansing

Condition:   Stasis; Colon
Intervention:  
Sponsor:   Gachon University Gil Medical Center
Unknown status

Wed, 23 Jan 2013 12:00:00 EST

A Phase I Trial of High-Dose Ascorbate in Glioblastoma Multiforme

Conditions:   Glioblastoma;   GBM;   Glioblastoma Multiforme
Interventions:   Drug: Ascorbate;   Drug: Temozolomide;   Radiation: Radiation therapy
Sponsors:   Joseph J. Cullen, MD, FACS;   National Institutes of Health (NIH);   National Cancer Institute (NCI)
Active, not recruiting

Wed, 19 Dec 2012 12:00:00 EST

Effect of Preoperative Aspirin in Patients Undergoing Off-pump Coronary Artery Bypass Grafting

Conditions:   Coronary Artery Disease;   Aspirin
Interventions:   Drug: Aspirin;   Drug: vitamin C
Sponsor:   Medinet Heart Centre
Unknown status

Thu, 09 Feb 2017 12:00:00 EST

Ischemia/Reperfusion Injury of Human Endothelium: Role of Glucose and Statins

Condition:   Hyperglycemia
Interventions:   Drug: 5% dextrose;   Drug: Vitamin C;   Drug: Simvastatin;   Drug: Sevoflurane
Sponsor:   US Department of Veterans Affairs
Completed

Thu, 15 Oct 2009 12:00:00 EDT

Gemcitabine, Ascorbate, Radiation Therapy for Pancreatic Cancer, Phase I

Condition:   Pancreatic Neoplasms
Interventions:   Drug: Ascorbate;   Drug: Gemcitabine;   Radiation: Radiation therapy
Sponsors:   Joseph J. Cullen;   Holden Comprehensive Cancer Center;   Gateway for Cancer Research
Active, not recruiting

Tue, 14 May 2013 12:00:00 EDT

Trial of IV vs Oral Iron Treatment of Iron Deficiency Anemia in the Post-Operative Bariatric Surgical Patient

Condition:   Iron Deficiency Anemia
Interventions:   Drug: Ferumoxytol;   Drug: Saline;   Drug: Ferrous sulfate tablets;   Drug: Vitamin C
Sponsors:   Auerbach Hematology Oncology Associates P C;   AMAG Pharmaceuticals, Inc.
Recruiting

Thu, 13 Feb 2020 12:00:00 EST

No Association Between Vitamin C and E Supplementation, Frailty, and Grip Strength Over Five Years: The CoLaus Study

Condition:   Frail Elderly Syndrome
Intervention:   Other: Observational cohort study
Sponsor:   Centre Hospitalier Universitaire Vaudois
Completed

Wed, 23 Aug 2017 12:00:00 EDT

Famine From Feast: Linking Vitamin C, Red Blood Cell Fragility, and Diabetes

Condition:   Diabetes Type 2
Intervention:  
Sponsor:   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Recruiting

Wed, 09 Apr 2014 12:00:00 EDT

Iron Bioavailability of Fortified Oat Drink

Condition:   Iron Absorption
Interventions:   Other: Dietary Intervention (with Vit C then without Vit C);   Other: Dietary Intervention (without Vit C followed by with Vit C)
Sponsors:   PepsiCo Global R&D;   Food and Nutrition Research Institute, Philippines
Completed

Thu, 25 Aug 2011 12:00:00 EDT

Efficacy and Tolerability of Apevitin BC Comparing to Vitamin Complex in Stimulating the Appetite

Condition:   Lack or Loss Appetite Nonorganic Origin
Interventions:   Drug: Apevitin BC;   Drug: Vitamin B Complex + Vitamin C
Sponsor:   EMS
Completed

Wed, 26 Jan 2011 12:00:00 EST

Intravenous (IV) Versus Oral Iron Treatment of Iron Deficiency Anemia in the Post-operative Bariatric Surgical Patient

Condition:   IDA in the Post-bariatric Surgical Patient
Interventions:   Drug: Ferumoxytol;   Drug: Ferrous sulfate;   Other: Oral vitamin C;   Other: Intravenous normal saline
Sponsors:   Johns Hopkins University;   AMAG Pharmaceuticals, Inc.
Withdrawn

Mon, 17 Dec 2018 12:00:00 EST

Evaluation of Ascorbate-Meglumine Therapeutic for SRS

Condition:   Safety
Intervention:   Drug: Ascorbate-Meglumine
Sponsors:   Chris Lascola, MD;   Duke University
Withdrawn

Thu, 25 Apr 2019 12:00:00 EDT

Clinical Trial With N-acetylcysteine and Bromhexine for COVID-19

Condition:   COVID-19
Interventions:   Drug: Vitamin C;   Drug: N-acetylcysteine (NAC);   Drug: NAC + Bromhexine (BMX)
Sponsors:   Universidade Federal do Ceara;   Paulista School of Medicine-EPM, UNIFESP;   Health Surveillance Secretariat - SVS;   Central Laboratory of Public Health of Ceara - LACEN-CE;   Leonardo da Vinci Hospital - HLV;   São José Hospital for Infectious Diseases - HSJ;   Ceará Health Secretariat - SESA;   Municipal Health Secretary - SMS-Fortaleza
Not yet recruiting

Wed, 16 Jun 2021 12:00:00 EDT

Combination Natural Health Product in Children With Attention Deficit/Hyperactivity Disorder (ADHD)

Condition:   Attention Deficit Hyperactivity Disorder
Intervention:   Dietary Supplement: Zinc, Magnesium, Vitamin B6, Vitamin C (Compound Natural Health Product for ADHD)
Sponsors:   Kieran Cooley;   The Canadian College of Naturopathic Medicine;   University of Toronto;   Centre for Addiction and Mental Health
Completed

Wed, 25 Jun 2008 12:00:00 EDT

Anthocyanin-rich Blackcurrant and Vascular Function

Conditions:   Vascular Stiffness;   Inflammation
Interventions:   Other: Beverage: Spray dried blackcurrant powder dissolved in water;   Other: Beverage: Placebo (sucrose, glucose, fructose, maltodextrin, malic acid, citric acid, vitamin C, artificial blackcurrant flavouring and low-nitrate water)
Sponsors:   University of Reading;   GlaxoSmithKline
Completed

Tue, 02 Jun 2015 12:00:00 EDT

The Efficacy of a Local Vitamin-C Rich Fruit (Guava) in Improving Iron Absorption From Mungbean Based Meals and Its Effect on Iron Status of Rural Indian Children (6-10 Years)

Conditions:   Iron Deficiency;   Anemia
Interventions:   Other: Mung Bean Meal;   Other: Guava
Sponsors:   Wageningen University;   CCS Haryana Agricultural University Hisar, India
Completed

Mon, 30 Aug 2010 12:00:00 EDT

Physiological Responses and Adaptation of Brown Adipose Tissue to Chronic Treatment With Beta 3-Adrenergic Receptor Agonists

Conditions:   Polycystic Ovary Syndrome;   Healthy Volunteers
Interventions:   Drug: Mirabegron;   Other: B Complex Plus Vitamin C Tablets
Sponsor:   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Recruiting

Fri, 10 Feb 2017 12:00:00 EST

Polyethylene Glycol Versus Low Volume Solutions Prior to Colonoscopy

Condition:   Colonoscopy
Interventions:   Drug: Polyethylene Glycols;   Drug: Natrium picosulfate / Magnesium citrate;   Drug: Polyethylene glycol / Ascorbic acid
Sponsors:   Tomas Bata Hospital, Czech Republic;   Brno University Hospital;   Faculty Hospital Kralovske Vinohrady
Completed

Fri, 04 Nov 2016 12:00:00 EDT

Modulation of Endothelial Dysfonction Using Vitamin C in Septic Shock Patients

Condition:   Septic Shock
Intervention:  
Sponsor:   Assistance Publique - Hôpitaux de Paris
Recruiting

Wed, 03 Mar 2021 12:00:00 EST

Oxidative Stress and Vitamin E Requirements

Condition:   Smoking
Intervention:   Drug: Vitamin E with and without Vitamin C
Sponsor:   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Completed

Mon, 08 Sep 2003 12:00:00 EDT

Comparison Between OSS and 2L PEG/Asc for Bowel Preparation of Elderly People

Condition:   Colonoscopy
Interventions:   Drug: Oral sulfate solution (OSS);   Drug: 2L PEG/Asc
Sponsor:   KangWon National University Hospital
Unknown status

Wed, 09 May 2018 12:00:00 EDT

The Effect of Antioxidant Vitamin Supplementation on Muscle Performance and Redox Status After Eccentric Training

Conditions:   Muscle Damage;   Oxidative Stress;   Hemolysis
Intervention:   Dietary Supplement: Antioxidant vitamins
Sponsors:   University of Thessaly;   European University Cyprus;   Greek Ministry of Development;   Democritus University of Thrace
Completed

Mon, 07 Feb 2011 12:00:00 EST

Study of Glutathione, Vitamin C and Cysteine in Children With Autism and Severe Behavior Problems

Conditions:   Autism;   Severe Behavior Disorder
Interventions:   Drug: placebo;   Drug: glutathione;   Drug: glutathione, vit C and NAC
Sponsors:   University of Louisville;   Cumberland Pharmaceuticals;   Norton Healthcare
Completed

Wed, 29 Apr 2009 12:00:00 EDT

Gemcitabine Plus Ascorbate for Sarcoma in Adults

Conditions:   Sarcoma;   Soft Tissue Sarcoma;   Unresectable Soft Tissue Sarcoma;   Metastatic Bone Tumor;   Bone Sarcoma
Interventions:   Drug: Ascorbate;   Drug: Gemcitabine
Sponsors:   Mohammed Milhem, MBBS;   University of Iowa Adolescent and Young Adult (AYA) Cancer Program;   St. Baldrick's Foundation;   University of Iowa
Terminated

Fri, 16 Mar 2018 12:00:00 EDT

Gender, Obesity, C-Reactive Protein, and Oxidative Stress

Condition:   Cardiovascular Disease
Interventions:   Dietary Supplement: Vitamin C;   Dietary Supplement: Vitamin E;   Dietary Supplement: Placebo
Sponsors:   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK);   University of California, Berkeley;   Kaiser Permanente
Completed

Mon, 22 Mar 2004 12:00:00 EST

Vitamin E and C to Slow Progression of Common Carotid Artery Plaque Build-Up

Conditions:   Cardiovascular Diseases;   Carotid Artery Diseases;   Intracranial Arteriosclerosis;   Cerebrovascular Disorders;   Heart Diseases;   Vascular Diseases;   Atherosclerosis
Interventions:   Drug: Vitamin E;   Drug: Vitamin C
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Terminated

Thu, 28 Oct 1999 12:00:00 EDT

Practicality of Intermittent Fasting and Its Effect on Markers of Aging and Oxidative Stress

Conditions:   Aging;   Metabolism
Interventions:   Other: Intermittent Fasting;   Dietary Supplement: 400 IU Vitamin E;   Dietary Supplement: 1000 mg Vitamin C
Sponsors:   University of Florida;   National Institutes of Health (NIH);   National Institute on Aging (NIA)
Completed

Tue, 06 May 2014 12:00:00 EDT

Treatment for COVID-19 in High-Risk Adult Outpatients

Conditions:   COVID-19;   SARS-CoV-2
Interventions:   Drug: Ascorbic Acid;   Drug: Hydroxychloroquine Sulfate;   Drug: Azithromycin;   Drug: Folic Acid;   Drug: Lopinavir 200 MG / Ritonavir 50 MG [Kaletra]
Sponsors:   University of Washington;   Bill and Melinda Gates Foundation
Active, not recruiting

Tue, 21 Apr 2020 12:00:00 EDT

Comparison of Different Low Volume Solutions Prior to Colonoscopy

Condition:   Colonoscopy
Interventions:   Drug: Natrium picosulfate / Magnesium citrate;   Drug: Polyethylene glycol / Ascorbic acid;   Drug: Natrium/ Kalium/ Magnesium sulfate
Sponsors:   Tomas Bata Hospital, Czech Republic;   Faculty Hospital Kralovske Vinohrady
Completed

Tue, 09 Oct 2018 12:00:00 EDT

The Impact of Vitamin on the Clinical Course in Cases Infected by Novel H1N1 Influenza Virus A

Condition:   H1N1 Influenza
Interventions:   Drug: Vitamin (vitamin A 15 mg,C 500 mg, E 400IU);   Drug: Placebo (digestive tablet)
Sponsor:   Seoul National University Hospital
Unknown status

Thu, 20 May 2010 12:00:00 EDT

A Phase I Study of High-dose L-methylfolate in Combination With Temozolomide and Bevacizumab in Recurrent High Grade Glioma

Condition:   Malignant Glioma
Interventions:   Drug: Bevacizumab;   Drug: Temozolomide;   Dietary Supplement: Vitamin C
Sponsor:   Vanderbilt-Ingram Cancer Center
Active, not recruiting

Wed, 03 Jul 2013 12:00:00 EDT

Study to Evaluate the Efficacy and Tolerability of Apevinat BC Compared to Vitamin Complex

Conditions:   Lack of Appetite;   Anorexia
Interventions:   Drug: Apevinat BC;   Drug: Vitamin Complex
Sponsor:   MDCPharma Produtos Farmaceuticos LTDA
Unknown status

Mon, 14 Feb 2011 12:00:00 EST

Pediatric COVID-19 and MIS-C Long-term Follow-up

Conditions:   Covid19;   MIS-C Associated With COVID-19;   MIS-C Multisystem Inflammatory Syndrome in Children;   SARS-CoV2 Infection
Intervention:  
Sponsors:   Children's National Research Institute;   National Institute of Allergy and Infectious Diseases (NIAID)
Recruiting

Mon, 05 Apr 2021 12:00:00 EDT

Physicians' Health Study II

Conditions:   Cancer;   Prostate Cancer;   Colorectal Cancer;   Cardiovascular Disease;   Eye Disease;   Cognitive Decline
Interventions:   Dietary Supplement: Vitamin E;   Dietary Supplement: Vitamin C;   Dietary Supplement: Multivitamin;   Dietary Supplement: Beta-carotene
Sponsors:   Brigham and Women's Hospital;   National Cancer Institute (NCI)
Completed

Wed, 28 Dec 2005 12:00:00 EST

Single Versus Multi-Dose Oral and Intravenous Tranexamic Acid Patients at High Risk for Blood Transfusion After Spine Surgery

Condition:   Open Posterior Thoracolumbar Spinal Fusion Procedure
Interventions:   Drug: Tranexamic Acid Injectable Product (1000 mg intravenous bolus);   Drug: Vitamin C 250 MG Oral Tablet;   Drug: Tranexamic Acid 650Mg Tablet
Sponsor:   Rush University Medical Center
Recruiting

Thu, 21 Feb 2019 12:00:00 EST

Study of the Effects of Vitamin C on Patients With Type 2 Diabetes

Conditions:   Diabetes Mellitus, Non-Insulin Dependent;   Non-Insulin Dependent
Intervention:   Drug: Acetylcholine
Sponsor:   National Center for Complementary and Integrative Health (NCCIH)
Completed

Thu, 04 Nov 1999 12:00:00 EST

Urinary Vitamin C Loss in Diabetic Subjects

Condition:   Diabetes
Intervention:  
Sponsor:   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Recruiting

Tue, 28 Oct 2003 12:00:00 EST

Effect of Simethicone on Bowel Preparation for Colonoscopy

Condition:   Colorectal Cancer
Interventions:   Drug: PEG-Asc;   Drug: PEG-Asc with simethicone
Sponsor:   Korea University Anam Hospital
Completed

Mon, 14 Sep 2015 12:00:00 EDT

Anti-inflammatory Dietary Intervention in Overweight and Obese Adolescents

Conditions:   Overweight;   Obesity
Interventions:   Dietary Supplement: Supplement containing fish oil, vitamin C, alpha-tocopherol, green tea extract and lycopene;   Dietary Supplement: Placebo supplement
Sponsors:   University College Dublin;   National Children's Research Centre, Ireland;   University of Dublin, Trinity College;   The Adelaide and Meath Hospital;   St. James's Hospital, Ireland
Completed

Wed, 15 Aug 2012 12:00:00 EDT

VCSIP Follow-up Study

Conditions:   Asthma;   Pulmonary Function;   Wheezing;   In Utero Nicotine
Intervention:   Other: No active intervention
Sponsors:   Oregon Health and Science University;   Indiana University;   National Institutes of Health (NIH)
Recruiting

Thu, 29 Jun 2017 12:00:00 EDT

Effect of Antioxidant on Endurance Performance in Healthy Men

Condition:   Exercise Tolerance
Interventions:   Dietary Supplement: Oligomerized litchi fruit extract;   Dietary Supplement: VItamin C + Vitamin E mixture;   Other: placebo
Sponsors:   Seoul National University Hospital;   University of California, Davis
Completed

Mon, 11 Aug 2008 12:00:00 EDT

The Efficacy and Safety of a Single 70% Glycolic Acid Peel With Vitamin C for the Treatment of Photoaging

Condition:   Photoaging
Intervention:   Drug: 70% glycolic acid
Sponsor:   National University Hospital, Singapore
Unknown status

Wed, 30 Apr 2014 12:00:00 EDT

The Efficacy and Safety of a Single 70% Glycolic Acid Peel With Vitamin C for the Treatment of Acne Scars

Condition:   Acne Scars
Intervention:   Drug: 70% glycolic acid
Sponsor:   National University Hospital, Singapore
Unknown status

Wed, 30 Apr 2014 12:00:00 EDT

Trial of Combination Therapy to Treat COVID-19 Infection

Conditions:   COVID;   Covid-19;   Corona Virus Infection;   Coronavirus Infection;   Coronavirus-19;   SARS-CoV2;   SARS-CoV Infection
Interventions:   Drug: Ivermectin;   Drug: Doxycycline Hcl;   Dietary Supplement: Zinc;   Dietary Supplement: Vitamin D3;   Dietary Supplement: Vitamin C
Sponsors:   ProgenaBiome;   Topelia Therapeutics
Recruiting

Wed, 22 Jul 2020 12:00:00 EDT

Effect of Supplementary Vitamins on Oxidant Gene Expression in the Lungs of Healthy Smokers

Condition:   Chronic Obstructive Pulmonary Disease (COPD)
Interventions:   Dietary Supplement: Group 1;   Dietary Supplement: Group 2
Sponsor:   Weill Medical College of Cornell University
Completed

Thu, 29 Nov 2007 12:00:00 EST

Clinical Trial to Measure the Maximun HR After ReConnect ® Supplementation vs. Placebo in CFS.

Condition:   Chronic Fatigue Syndrome
Interventions:   Dietary Supplement: ReConnect (NADH plus CoQ10);   Dietary Supplement: placebo
Sponsors:   Hospital Universitari Vall d'Hebron Research Institute;   VITAE NATURAL NUTRITION, S.L.
Completed

Fri, 14 Feb 2014 12:00:00 EST

A Phase 2 Trial of High-dose Ascorbate for Pancreatic Cancer (PACMAN 2.1)

Conditions:   Pancreatic Neoplasms;   Cancer of Pancreas;   Cancer of the Pancreas;   Neoplasms, Pancreatic;   Pancreas Cancer;   Pancreas Neoplasms;   Adenocarcinoma
Interventions:   Drug: Gemcitabine;   Drug: nab-paclitaxel;   Drug: Pharmacological ascorbate
Sponsors:   Joseph J. Cullen;   National Institutes of Health (NIH);   National Cancer Institute (NCI);   Holden Comprehensive Cancer Center;   McGuff Pharmaceuticals, Inc.
Recruiting

Mon, 19 Sep 2016 12:00:00 EDT

Improvement of Tolerance of Bowel Cleansing Before Colonoscopy in Diabetic Patients

Conditions:   Diabetes Mellitus;   Colonic Diseases
Interventions:   Drug: PEG-ascorbate 2L;   Drug: PEG 4L
Sponsors:   Parc de Salut Mar;   Germans Trias i Pujol Hospital
Completed

Fri, 21 Nov 2014 12:00:00 EST

Is it Fair to Use Antibiotics After Laparoscopic Cholecystectomy for the Patients With Acutely Inflamed Gallbladder?

Condition:   Acute Cholecystitis
Interventions:   Drug: Cephalosporin;   Drug: Placebo
Sponsors:   Taeho Hong;   Incheon St.Mary's Hospital;   Bucheon St. Mary's Hospital;   Uijeongbu St. Mary Hospital;   Catholic University of Korea Saint Paul's Hospital
Completed

Fri, 03 Jul 2015 12:00:00 EDT

A Preventive Treatment for Migrant Workers at High-risk of COVID-19

Condition:   Covid-19
Interventions:   Drug: Hydroxychloroquine Sulfate Tablets;   Drug: Ivermectin 3mg Tab;   Drug: Zinc;   Drug: Povidone-Iodine;   Dietary Supplement: Vitamin C
Sponsor:   National University Hospital, Singapore
Completed

Wed, 24 Jun 2020 12:00:00 EDT

Effects of Low-dose Complex B-vitamins on Homocysteine and Framingham Risk Score Among Chinese Elderly

Condition:   Hyperhomocysteinemia
Intervention:   Dietary Supplement: Low-dose complex B-vitamins
Sponsors:   Peking University;   Institute of reproductive and Child Health;   National Natural Science Foundation of China
Completed

Fri, 19 Sep 2008 12:00:00 EDT

A Study to See if Certain Antioxidants and Vitamins Will Keep Lactate Levels Down in Patients Taking Anti-HIV Drugs

Condition:   HIV Infections
Interventions:   Drug: Thiamine hydrochloride;   Drug: Riboflavin;   Drug: Ascorbic acid;   Drug: Vitamin E
Sponsor:   National Institute of Allergy and Infectious Diseases (NIAID)
Withdrawn

Wed, 15 May 2002 12:00:00 EDT

Different Bowel Preparations for Colonoscopy In Children

Condition:   Colonoscopy
Interventions:   Device: PEG-4000 with citrates and simethicone;   Device: polyethylene glycol 4000 solution with simethicon;   Device: polyethylene glycol 3350 hyper-osmotic solution with ascorbic acid;   Device: sodium picosulphate plus magnesium oxide and citric acid
Sponsor:   Azienda Policlinico Umberto I
Unknown status

Mon, 22 Oct 2012 12:00:00 EDT

Efficacy and Safety Study of BLS_ILB_E710c for the Fertile Women With Cervical Intraepithelial Neoplasia(CIN3)

Condition:   Cervical Intraepithelial Neoplasia
Interventions:   Drug: BLS_ILS_E710c 500mg;   Drug: BLS_ILB_710c 1000mg;   Drug: BLS_ILS_E710c 1500mg
Sponsor:   BioLeaders Corporation
Completed

Mon, 21 Jul 2014 12:00:00 EDT

Bowel Preparation for Colonoscopy in the Elderly

Conditions:   Bowel Preparation;   Colonoscopy
Interventions:   Drug: Standard full-volume PEG;   Drug: Split-dose full-volume PEG;   Drug: Split-dose low-volume PEG
Sponsors:   Kyunghee University Medical Center;   Kangbuk Samsung Hospital;   Hanyang University
Completed

Thu, 13 Nov 2014 12:00:00 EST

Pre- and Postoperative Nutrition in Head and Neck Cancer Patients

Condition:   Head and Neck Cancer
Interventions:   Dietary Supplement: Nutritional supplement (Protein + MIX);   Dietary Supplement: Nutritional supplement (Protein)
Sponsors:   University of Copenhagen;   Rigshospitalet, Denmark
Completed

Mon, 21 May 2018 12:00:00 EDT

Dietary Supplements for COVID-19

Condition:   Covid19
Interventions:   Drug: Vitamin D3 50,000 IU;   Dietary Supplement: Vitamin C/Zinc;   Dietary Supplement: Vitamin K2/D;   Other: Microcrystalline Cellulose Capsule;   Other: Medium Chain Triglyceride Oil
Sponsors:   The Canadian College of Naturopathic Medicine;   Ottawa Hospital Research Institute;   Vitazan Professional;   New Roots Herbal
Recruiting

Wed, 03 Mar 2021 12:00:00 EST

Vitamin E Pharmacokinetics and Biomarkers in Normal and Obese Women

Conditions:   Diabetes;   Fatty Liver;   Obesity;   Healthy Volunteers
Interventions:   Drug: Alpha tocopherol;   Other: Vitamin E;   Other: Vitamin C
Sponsor:   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Recruiting

Mon, 16 Mar 2009 12:00:00 EDT

Preventive Application of GnRH Antagonist on Early OHSS

Conditions:   Ovarian Hyperstimulation Syndrome;   GnRH Antagonist;   Aspirin;   Vascular Endothelial Growth Factor;   Pigment Epithelium Derived Factor
Interventions:   Drug: GnRH antagonist;   Drug: aspirin
Sponsor:   First Affiliated Hospital, Sun Yat-Sen University
Unknown status

Thu, 15 Jun 2017 12:00:00 EDT

The Impact of Additional Oral Preparation on the Quality of Bowel Preparation for Colonoscopy

Condition:   Bowel Preparation Quality
Interventions:   Drug: Additional oral preparation (3L of PEG+Asc, "Coolprep®");   Drug: Standard oral preparation (2L of PEG+Asc, "Coolprep®")
Sponsor:   Kyungpook National University Hospital
Completed

Thu, 03 Sep 2015 12:00:00 EDT

Antioxidants and Zinc Improving Minimal Hepatic Encephalopathy In Truck Drivers; a Pilot Study

Condition:   Minimal Hepatic Encephalopathy
Interventions:   Dietary Supplement: 175 mg zinc gluconate, 50000 IU vitamin A, 500 mg vitamin C and 100 mg vitamin E once daily plus lactulose; dose 30-60 ml/day for 3 months;   Dietary Supplement: Lactulose
Sponsor:   Mansoura University
Completed

Thu, 13 Aug 2015 12:00:00 EDT

Comparative Efficacy of Different Mebendazole Polymorphs in the Treatment of Soil-transmitted Helminth Infections

Condition:   Necator Americanus Infection
Interventions:   Drug: Mebendazole polymorph A and C 500 mg;   Drug: Mebendazole polymorph C;   Drug: Placebo
Sponsor:   University of Kelaniya
Completed

Mon, 09 May 2011 12:00:00 EDT

The Effect of Exercises on Physiological Changes and Clinical Symptoms in Allergic Rhinitis Patients

Condition:   Allergic Rhinitis
Interventions:   Other: Aerobic exercise with Vit. C;   Other: Aerobic exercise;   Other: No exercise
Sponsor:   Chulalongkorn University
Completed

Mon, 28 Apr 2014 12:00:00 EDT

Oral Arsenic Trioxide for NPM1-mutated AML

Condition:   NPMc+ AML
Intervention:   Drug: Oral Arsenic Trioxide Formulation
Sponsor:   The University of Hong Kong
Recruiting

Wed, 30 Dec 2020 12:00:00 EST

Anglo-Scandinavian Cardiac Outcomes Trial: Post Trial Follow-Up Study

Conditions:   Hypertension;   Diabetes;   Death From Cardiovascular Disease;   Myocardial Infarction;   Stroke
Intervention:  
Sponsors:   Imperial College London;   Pfizer
Completed

Mon, 26 Dec 2011 12:00:00 EST

Acne Treatment With Active Patches Which Contains Azelaic Acid, Citric Acid,Salicylic Acid and 2% Ascorbic Acid

Condition:   Acne Vulgaris
Interventions:   Device: OPLON active patch;   Device: Sham patch
Sponsor:   Oplon-Pure Science Ltd.
Completed

Wed, 11 Aug 2010 12:00:00 EDT

Effect Study of Montelukast to Treat Asthma Detected by LTD4 Bronchial Effect Study of Montelukast to Treat Asthma Detected by LTD4 Bronchial Provocation Test

Condition:   Bronchial Asthma
Intervention:  
Sponsor:   Guangzhou Institute of Respiratory Disease
Unknown status

Thu, 03 Jan 2013 12:00:00 EST

The Impact of Split Dose of Low-volume Polyethylene Glycol on Adenoma Detection Rate

Condition:   Colonic Adenomas
Intervention:   Drug: Split dose low-volume PEG solution
Sponsors:   Valduce Hospital;   Istituto Clinico Humanitas;   Istituti Ospitalieri di Cremona;   Nuovo Regina Margherita Hospital
Unknown status

Mon, 30 Jun 2014 12:00:00 EDT

Effect of a Nitric Oxide Supplementation Product on Endothelial Dysfunction and Prehypertensive Adults

Condition:   Hypertension
Intervention:   Dietary Supplement: NEO40 Daily
Sponsors:   Hypertension Institute, Nashville;   Neogenis Laboratories
Completed

Fri, 29 Mar 2019 12:00:00 EDT

EoE Food Desensitization

Condition:   Eosinophilic Esophagitis
Intervention:   Other: Oral food desensitization
Sponsor:   The University of Texas Health Science Center, Houston
Recruiting

Mon, 29 Aug 2016 12:00:00 EDT

Treating Oxidative Stress and the Metabolic Pathology of Autism

Condition:   Autistic Disorder
Interventions:   Dietary Supplement: B12;   Dietary Supplement: Placebo;   Dietary Supplement: folate;   Dietary Supplement: B complex;   Dietary Supplement: vitamin C;   Dietary Supplement: cod liver oil;   Dietary Supplement: Mineral complex;   Dietary Supplement: carnitine
Sponsor:   Arkansas Children's Hospital Research Institute
Completed

Thu, 13 Dec 2007 12:00:00 EST

Herbal Mouthrinse for Oral Mucositis Study

Condition:   Oral Mucositis
Interventions:   Drug: Neem Mouthrinse;   Drug: Placebo Mouthrinse
Sponsors:   Medical University of South Carolina;   National Cancer Institute (NCI)
Completed

Fri, 12 Jul 2013 12:00:00 EDT

Racial and Aging Effects of Acute Antioxidant Supplementation

Condition:   Healthy
Interventions:   Dietary Supplement: Antioxidant;   Other: Placebo
Sponsor:   University of Illinois at Chicago
Completed

Thu, 05 Jun 2014 12:00:00 EDT

A Study on the Safety and Efficacy of Nitric Oxide Gel in Subjects With Painful Diabetic Neuropathy

Condition:   Neuropathic Pain
Interventions:   Drug: nitric oxide gel;   Drug: placebo gel
Sponsor:   China Medical University Hospital
Completed

Wed, 04 Jul 2012 12:00:00 EDT

Study Evaluating the Efficacy of an Ibuprofen Effervescent Tablet in the Treatment of Post-Surgical Dental Pain

Condition:   Pain
Interventions:   Drug: effervescent ibuprofen tablets;   Drug: effervescent Aspirin plus Vitamin C tablets;   Drug: ibuprofen tablets;   Drug: placebo
Sponsor:   Wyeth is now a wholly owned subsidiary of Pfizer
Completed

Fri, 07 Mar 2008 12:00:00 EST

The Role of Vitamins E and C in Maintaining Lung Health in People With Asthma

Condition:   Asthma
Intervention:   Dietary Supplement: Vitamin
Sponsors:   University of North Carolina, Chapel Hill;   National Center for Complementary and Integrative Health (NCCIH)
Completed

Fri, 02 Sep 2005 12:00:00 EDT

Ixazomib as a Replacement for Carfilzomib and Bortezomib for Multiple Myeloma Patients

Condition:   Multiple Myeloma
Interventions:   Drug: Melphalan;   Drug: Prednisone;   Drug: Cyclophosphamide;   Drug: Dexamethasone;   Dietary Supplement: Ascorbic acid;   Drug: PLD;   Drug: Lenalidomide;   Drug: Pomalidomide
Sponsors:   Oncotherapeutics;   Takeda
Active, not recruiting

Fri, 01 Aug 2014 12:00:00 EDT

A Safety Study of Pharmacologic Ascorbate and Ferumoxytol in Addition to Standard of Care Chemoradiation in Glioblastoma

Conditions:   Glioblastoma;   Glioblastoma Multiforme
Interventions:   Drug: Ferumoxytol injection;   Drug: Pharmacological ascorbate;   Radiation: External beam radiation therapy;   Drug: Temozolomide
Sponsors:   Bryan Allen;   Holden Comprehensive Cancer Center
Not yet recruiting

Tue, 25 May 2021 12:00:00 EDT

The Effectiveness of Micronutrient Supplements on Growth and Educational Achievement of Schoolchildren in Bangladesh

Condition:   Micronutrient Deficiencies
Intervention:   Dietary Supplement: Multiple micronutrients
Sponsors:   Save the Children;   University of Westminster;   Harvard University
Unknown status

Wed, 11 Mar 2009 12:00:00 EDT

Iron Absorption From a Wheat-based Instant Cereal:Gut and Stable Isotope Studies in Kenyan Infants

Conditions:   Iron Absorption;   Gut Microbiota
Interventions:   Dietary Supplement: FeFum and 7.5 g prebiotic mixture;   Dietary Supplement: FeFum and 3 g prebiotic mixture;   Dietary Supplement: Fefum and no prebiotic mixture
Sponsors:   Swiss Federal Institute of Technology;   Danone Nutricia Research
Completed

Thu, 28 Mar 2019 12:00:00 EDT

Acne Treatment With Active Oplon's Patches - 15-18 Years Old

Condition:   Acne Vulgaris
Interventions:   Device: Oplon Active Patch;   Device: Placebo Patch
Sponsor:   Oplon-Pure Science Ltd.
Unknown status

Wed, 15 Dec 2010 12:00:00 EST

Acne Treatment With Active Oplon's Patches

Condition:   Acne Vulgaris
Interventions:   Device: Oplon Active Patch;   Device: Placebo Patch
Sponsor:   Oplon-Pure Science Ltd.
Completed

Thu, 12 Aug 2010 12:00:00 EDT

Effectiveness of Bisacodyl Suppository Agent for Dose Reduction of Low Dose PEG

Condition:   Bowel Preparation
Interventions:   Drug: 2L PEG-Asc;   Drug: Bisacodyl 10Mg Suppository;   Drug: 1L PEG-Asc
Sponsor:   Samsung Medical Center
Completed

Thu, 21 Feb 2019 12:00:00 EST

Mechanisms for Vascular Dysfunction and Exercise Tolerance in CF

Condition:   Cystic Fibrosis
Interventions:   Dietary Supplement: Acute Antioxidant;   Dietary Supplement: Chronic Antioxidant;   Other: Placebo
Sponsor:   Augusta University
Recruiting

Wed, 24 Feb 2016 12:00:00 EST

Clinical Trial of Antioxidant Therapy in Patients With Septic Shock

Conditions:   Oxidative Stress;   Septic Shock
Interventions:   Drug: Melatonin 5 mg;   Drug: Vitamin C 1 GM Oral Tablet;   Drug: Vitamin E 400 UNT;   Drug: N-acetylcysteine
Sponsor:   American British Cowdray Medical Center
Active, not recruiting

Thu, 14 Jun 2018 12:00:00 EDT

Polyglucosamine L112 in Overweight and Obese Subjects

Condition:   Obesity
Interventions:   Dietary Supplement: Polyglucosamine L112;   Combination Product: Placebo
Sponsor:   Azienda di Servizi alla Persona di Pavia
Completed

Thu, 26 Aug 2021 12:00:00 EDT

Impact Of Antioxidant Micronutrients On Intensive Care Unit (ICU) Outcome

Conditions:   Critically Ill Patients;   Cardiac Surgery;   Trauma;   Subarachnoid Hemorrhage
Interventions:   Drug: Selenium (Se), Zinc (Zn), Vitamin C, Vitamin B1, Vitamin E;   Drug: Placebo
Sponsors:   Centre Hospitalier Universitaire Vaudois;   Fresenius Kabi
Terminated

Tue, 14 Aug 2007 12:00:00 EDT

Supplemental Adjuvants for Intracellular Nutrition and Treatment

Conditions:   Neovascular Age-related Macular Degeneration;   Diabetic Macular Edema
Interventions:   Drug: Neutral pills with no medicinal effect;   Dietary Supplement: Inosine; Tocopherols, Tocotrienol, CoQ10 combination capsule; Niacinamide SR; Viatmin C; N-acetyl Cysteine; Complete Multivitamin with all minerals;   Drug: Inosine; Tocopherol, Tocotrienol, CoQ10 combination capsule; Niacinamide; Vitamin C; N-acetyl Cysteine; Complete Multivitamin with all minerals; Minocycline
Sponsors:   Mid-Atlantic Retina Consultations, Inc.;   West Virginia University
Unknown status

Wed, 06 May 2009 12:00:00 EDT

Safety and Immunogenicity of Single Dose Choleragarde® in HIV-Seropositive Adults

Conditions:   Cholera;   Vibrio Infections;   Diarrhea
Interventions:   Biological: CholeraGarde®;   Biological: Placebo
Sponsors:   International Vaccine Institute;   Vaccine Technologies Inc.;   Siriraj Hospital
Completed

Tue, 26 Aug 2008 12:00:00 EDT

Absorption, Stable Isotope Appearance and Non-transferrin-bound Iron (NTBI) Profile From NaFeEDTA and Ferrous Sulphate

Condition:   Iron Deficiency
Interventions:   Dietary Supplement: Porridge fortified with either NaFeEDTA;   Dietary Supplement: FeSO4
Sponsors:   Swiss Federal Institute of Technology;   DSM Nutritional Products, Inc.
Completed

Thu, 21 Jan 2010 12:00:00 EST

Antioxidants as Adjuvant Therapy to Standard Therapy in Patients With COVID-19

Conditions:   Pneumonia, Viral;   Covid19;   ARDS;   Oxidative Stress
Interventions:   Drug: Vitamin C;   Drug: Vitamin E;   Drug: Melatonin;   Drug: N-acetyl cysteine;   Drug: Pentoxifylline
Sponsors:   Unidad Temporal COVID-19 en Centro Citibanamex;   Instituto Nacional de Cardiologia Ignacio Chavez;   Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Completed

Wed, 30 Sep 2020 12:00:00 EDT

Gemcitabine With Ascorbate Including Adolescents

Conditions:   Soft Tissue Sarcoma;   Bone Sarcoma;   Unresectable Soft Tissue Sarcoma;   Metastatic Bone Sarcoma;   Metastatic Soft-tissue Sarcoma;   Unresectable Bone Sarcoma
Interventions:   Drug: Ascorbate;   Drug: Gemcitabine
Sponsor:   William Terry
Not yet recruiting

Fri, 07 May 2021 12:00:00 EDT

Hookah Smoking, Carbon Monoxide, and Coronary Endothelial Function

Conditions:   Smoking;   Endothelial Dysfunction
Interventions:   Other: Charcoal hookah;   Other: E-coal hookah;   Other: Cigarette;   Drug: Carbon Monoxide inhalation;   Other: Room Air inhalation;   Drug: vitamin C;   Drug: tadalafil
Sponsors:   Cedars-Sinai Medical Center;   National Institutes of Health (NIH);   National Institute on Drug Abuse (NIDA)
Terminated

Thu, 25 May 2017 12:00:00 EDT

Effect of Inorganic Nitrate Supplement on Blood Pressure

Conditions:   Blood Pressure;   Endothelial Dysfunction
Interventions:   Dietary Supplement: Plant based bioequivalent Nitrate supplementation;   Dietary Supplement: Placebo
Sponsor:   Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Completed

Wed, 10 Apr 2019 12:00:00 EDT

Antioxidant Supplement and Reduction of Metachronous Adenomas of the Large Bowel: a Double Blind Randomized Trial

Condition:   Colorectal Adenomas
Interventions:   Drug: antioxidants;   Drug: placebo
Sponsors:   IRCCS Azienda Ospedaliera Universitaria San Martino - IST Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy;   LILT (Italian league against cancer)
Terminated

Wed, 21 Sep 2011 12:00:00 EDT

Interventional Testing of Gene-environment Interactions Via the Verifomics Mobile Application

Conditions:   Obesity;   Rhinitis;   Rhinitis, Allergic;   Respiratory Sounds;   Dyspnea;   Headache;   Migraine Disorders;   Arthritis;   Arthralgia;   Anxiety;   Sleep Initiation and Maintenance Disorders;   Sleep Deprivation
Interventions:   Dietary Supplement: Vitamin A;   Dietary Supplement: Vitamin B6;   Dietary Supplement: Vitamin C;   Dietary Supplement: Nicotinamide;   Dietary Supplement: Vitamin D3;   Dietary Supplement: Vitamin E;   Other: Broccoli;   Other: Spinach;   Dietary Supplement: Caffeine;   Other: Coffee;   Device: Axon Eyewear;   Other: Chocolate
Sponsor:   Verifomics LLC
Terminated

Tue, 03 May 2016 12:00:00 EDT

Evaluation of the Efficacy of Different Strategies to Treat Anemia in Mexican Children

Condition:   Anemia
Interventions:   Dietary Supplement: Iron;   Dietary Supplement: Multiple micronutrients supplement;   Dietary Supplement: micronutrient fortified porridge powder;   Dietary Supplement: Iron and ascorbic acid fortified water;   Dietary Supplement: Iron plus folic acid supplement
Sponsors:   Universidad Autonoma de Queretaro;   Procter and Gamble
Completed

Wed, 14 Jan 2009 12:00:00 EST

Gelatin, Collagen, Gummy and PINP

Condition:   Collagen Synthesis
Intervention:   Other: gelatin, collagen, gummy dose
Sponsor:   University of California, Davis
Completed

Wed, 29 Nov 2017 12:00:00 EST

An Investigation Into the Effects of Blueberry Anthocyanin on Cognitive Functioning and Mood in Adolescents.

Condition:   Depression
Interventions:   Dietary Supplement: Wild Blueberry Powder-13g;   Dietary Supplement: Placebo
Sponsors:   University of Reading;   Wild Blueberry Association of North America (WBANA)
Unknown status

Tue, 18 Apr 2017 12:00:00 EDT

Impact of Antioxidant Agents on the Number of DNA Double-strand Breaks After Radiation-based Cardiac Examinations

Condition:   Focus of the Study: DNA Damage Due to Medical Diagnostic X-ray
Interventions:   Radiation: Low-dose radiation exposure;   Radiation: High-dose radiation exposure;   Other: No radiation exposure
Sponsor:   University of Zurich
Completed

Mon, 16 Apr 2012 12:00:00 EDT

Anti-Oxidant Treatment of Alzheimer's Disease

Condition:   Alzheimer's Disease
Interventions:   Drug: Vitamin E, Vitamin C, and Alpha-lipoic Acid;   Drug: Coenzyme Q;   Drug: Placebo capsules;   Drug: Placebo wafers
Sponsors:   National Institute on Aging (NIA);   Alzheimer's Disease Cooperative Study (ADCS)
Completed

Wed, 06 Jul 2005 12:00:00 EDT

Inflammatory Mediators in Obstructive Sleep Apnoea Syndrome; Mechanisms of Production and the Effect of Long Term Antioxidants Administration

Condition:   Obstructive Sleep Apnea Syndrome
Interventions:   Device: n-CPAP;   Device: Oxygen supplementation;   Drug: Vitamin A, Vitamin C, Vitamin E, Allopurinol, N-Acetylcysteine
Sponsor:   University of Athens
Unknown status

Wed, 25 Aug 2010 12:00:00 EDT

1L- vs. 4L-PEG for Bowel Preparation Among Inpatients.

Conditions:   Colonoscopy;   Hospitalized Patients;   Bowel Preparation
Interventions:   Drug: 1L-PEG;   Drug: 4L-PEG
Sponsor:   IRCCS Azienda Ospedaliero-Universitaria di Bologna
Completed

Tue, 17 Mar 2020 12:00:00 EDT

Managing Endothelial Dysfunction in COVID-19 : A Randomized Controlled Trial at LAUMC

Condition:   Covid19
Interventions:   Drug: Atorvastatin + L-arginine + Folic acid + Nicorandil + Nebivolol;   Drug: Placebo
Sponsor:   Lebanese American University Medical Center
Recruiting

Tue, 17 Nov 2020 12:00:00 EST

The Role of Antioxidant Supplementation in Keratoconus Patients

Condition:   Keratoconus
Interventions:   Other: Antioxidants (Vitamins A,C,E) plus GSH;   Other: Placebo;   Dietary Supplement: Centrum;   Combination Product: Dietary Sources
Sponsors:   University of Miami;   Fight for Sight
Withdrawn

Mon, 11 Jul 2016 12:00:00 EDT

Genetic Information and Dietary Intake Behaviour

Condition:   Healthy
Interventions:   Other: Dietary advice with genetic information;   Other: General dietary recommendations
Sponsors:   University of Toronto;   Advance Foods and Materials Network
Completed

Thu, 12 May 2011 12:00:00 EDT

The Effect of 12-week Dietary Intake of Syrup Containing CoQ10 and Collagen on Dermis Density and Other Skin Parameters

Conditions:   Dermis Density;   Trans Epidermal Water Loss (TEWL);   Skin Hydration;   Wrinkles;   Dermis Thickness
Interventions:   Dietary Supplement: Test syrup containing CoQ10 and collagen;   Dietary Supplement: Placebo syrup
Sponsors:   Higher School of Applied Sciences (VIST);   European Regional Development Fund;   Valens Int. d.o.o., Slovenija;   Ministry of Education, Science and Sport, Republic of Slovenia
Completed

Tue, 22 Jan 2019 12:00:00 EST

Nutrient Fortified Oat Drink

Condition:   Iron Deficiency Anemia
Intervention:   Other: Dietary Intervention
Sponsors:   PepsiCo Global R&D;   PepsiCo - Philippines
Unknown status

Wed, 17 Aug 2011 12:00:00 EDT

Study Comparing the Bowel Cleansing Efficacy of PLENVU® Versus SELG-ESSE® Using a 2-Day Split Dosing Regimen.

Conditions:   Colon Polyp;   Colon Adenoma;   Colon Lesion
Interventions:   Drug: PEG3350;   Drug: Macrogol 4000
Sponsor:   Istituto Clinico Humanitas
Completed

Thu, 15 Nov 2018 12:00:00 EST

Effect of Acute Red Raspberry Consumption on Post-prandial Oxidative Stress

Conditions:   Oxidative Stress;   Antioxidants
Interventions:   Dietary Supplement: red raspberries;   Dietary Supplement: bread controls
Sponsors:   University of Toronto;   Unity Health Toronto
Completed

Tue, 16 Nov 2010 12:00:00 EST

Impact of Varying Doses of Amino Acids on Exercise, Muscular and Mental Performance

Condition:   Psychological Phenomena: Central Fatigue
Interventions:   Dietary Supplement: AminoVital Amino Acid formulation;   Dietary Supplement: Amino Vital Amino Acid formulation
Sponsors:   McMaster University;   Ajinomoto USA, INC.
Completed

Wed, 06 Oct 2010 12:00:00 EDT

A Study of Quintuple Therapy to Treat COVID-19 Infection

Conditions:   COVID-19;   Corona Virus Infection;   Coronavirus-19;   Sars-CoV2
Interventions:   Drug: Hydroxychloroquine;   Drug: Azithromycin;   Dietary Supplement: Vitamin C;   Dietary Supplement: Vitamin D;   Dietary Supplement: Zinc
Sponsors:   ProgenaBiome;   DSCS CRO
Recruiting

Mon, 06 Apr 2020 12:00:00 EDT

Nitric Oxide Bioavailability and Early Life Stress (NO-Stress)

Condition:   Cardiovascular Disease
Interventions:   Dietary Supplement: Antioxidant cocktail;   Other: Biopsy;   Other: Placebo;   Drug: NMD; 0.4mg sub-lingual nitroglycerin spray
Sponsors:   Augusta University;   National Heart, Lung, and Blood Institute (NHLBI)
Enrolling by invitation

Wed, 16 Apr 2014 12:00:00 EDT

Long Term Nitric Oxide Bioavailability on Vascular Health in Chronic Obstructive Pulmonary Disease

Condition:   Chronic Obstructive Pulmonary Disease (COPD)
Interventions:   Drug: Tetrahydrobiopterin (BH4);   Dietary Supplement: Antioxidant Cocktail
Sponsor:   Augusta University
Completed

Tue, 17 May 2016 12:00:00 EDT

Nutritional Intervention and Respiratory Infections in Older Subjects

Conditions:   Upper Respiratory Infections;   Lower Respiratory Tract Infections
Intervention:   Dietary Supplement: Multivitamins and minerals
Sponsors:   Corporacion Ecuatoriana de Biotecnologia;   Universidad Central del Ecuador
Unknown status

Tue, 29 Oct 2013 12:00:00 EDT

Single Versus Multi-Dose Oral Tranexamic Acid in Patients at High Risk for Blood Transfusion After Total Joint Arthroplasty

Conditions:   Anemia;   Arthritis;   Total Knee Arthroplasty;   Total Hip Arthroplasty
Interventions:   Drug: Conventional Oral TXA (Tranexamic Acid);   Drug: Multi-Dose Oral TXA (Tranexamic Acid)
Sponsor:   Rush University Medical Center
Terminated

Thu, 06 Oct 2016 12:00:00 EDT

Nebivolol and Endothelial Regulation of Fibrinolysis (NERF)

Conditions:   Prehypertension;   Hypertension
Interventions:   Drug: Nebivolol;   Drug: Metoprolol;   Drug: Placebo;   Other: Bradykinin;   Other: Saline;   Other: Vitamin C
Sponsors:   University of Colorado, Boulder;   Forest Laboratories
Completed

Thu, 10 May 2012 12:00:00 EDT

Australasian COVID-19 Trial (ASCOT) ADAptive Platform Trial

Condition:   SARS-CoV-2 Infection (COVID-19)
Interventions:   Drug: Nafamostat Mesilate;   Biological: Hyperimmune Globulin;   Drug: Enoxaparin;   Drug: Dalteparin;   Drug: Tinzaparin
Sponsors:   University of Melbourne;   The Peter Doherty Institute for Infection and Immunity;   Australasian Society for Infectious Diseases;   Middlemore Clinical Trials;   The George Institute;   Hunter Medical Research Institute;   The University of Queensland
Recruiting

Thu, 23 Jul 2020 12:00:00 EDT

Effect of Prenatal Nutritional Supplementation on Birth Outcome in Hounde District, Burkina Faso

Conditions:   Intrauterine Growth Retardation;   Low Birth Weight
Interventions:   Dietary Supplement: UNIMMAP - multiple micronutrients;   Dietary Supplement: Food supplement enriched with multiple micronutrients
Sponsors:   Institute of Tropical Medicine, Belgium;   University Ghent;   Flemish Interuniversity Council (VLIR);   Nutrition Third World, Belgium
Completed

Fri, 29 May 2009 12:00:00 EDT

Adjunctive Steroid Combination in Ocular Trauma (ASCOT) Study

Condition:   Eye Injury Trauma
Intervention:   Drug: Triamcinolone Acetonide
Sponsor:   Moorfields Eye Hospital NHS Foundation Trust
Completed

Fri, 19 Aug 2016 12:00:00 EDT

FLIPS: Ferfer Liposomal Iron Performance Study

Condition:   Iron Deficiency Anemia
Intervention:   Drug: Iron Supplement
Sponsor:   PharmEvo Pvt Ltd
Completed

Thu, 13 Apr 2017 12:00:00 EDT

Males, Antioxidants, and Infertility Trial

Condition:   Male Infertility
Interventions:   Drug: Antioxidant Supplement;   Other: Placebo
Sponsors:   Yale University;   University of North Carolina;   Augusta University;   Penn State University;   University of California, San Francisco;   University of Oklahoma;   University of Pennsylvania
Completed

Tue, 21 Apr 2015 12:00:00 EDT

Changes in Microbiota and Iron Status After Iron Fortification of Complementary Foods

Condition:   Bacterial Infections
Interventions:   Dietary Supplement: fortification with iron and micronutrients;   Dietary Supplement: Sprinkles
Sponsors:   Swiss Federal Institute of Technology;   University of KwaZulu;   University of Nairobi
Completed

Wed, 28 Apr 2010 12:00:00 EDT

Impact of a Nutritional Supplement on the Recovery of the Nutritional Status of Patients With Spontaneous Hip Fracture

Conditions:   Hip Fractures;   Malnutrition
Interventions:   Dietary Supplement: FontActiv Superprotein/Hypercaloric Fiber;   Dietary Supplement: Carbohydrates and C Vitamin
Sponsor:   Laboratorios Ordesa
Not yet recruiting

Tue, 03 Dec 2019 12:00:00 EST

Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired Pneumonia

Condition:   Community-acquired Pneumonia, Influenza, COVID-19
Interventions:   Drug: Fixed-duration Hydrocortisone;   Drug: Shock-dependent hydrocortisone;   Drug: Ceftriaxone;   Drug: Moxifloxacin or Levofloxacin;   Drug: Piperacillin-tazobactam;   Drug: Ceftaroline;   Drug: Amoxicillin-clavulanate;   Drug: Macrolide administered for 3-5 days;   Drug: Macrolide administered for up to 14 days;   Drug: Five-days oseltamivir;   Drug: Ten-days oseltamivir;   Drug: Lopinavir/ritonavir;   Drug: Hydroxychloroquine;   Drug: Hydroxychloroquine + lopinavir/ritonavir;   Drug: Interferon-β1a;   Drug: Anakinra;   Drug: Fixed-duration higher dose Hydrocortisone;   Drug: Tocilizumab;   Drug: Sarilumab;   Drug: Vitamin C;   Drug: Therapeutic anticoagulation;   Drug: Simvastatin;   Biological: Convalescent plasma;   Other: Protocolised mechanical ventilation strategy;   Drug: Eritoran;   Drug: Apremilast;   Drug: Aspirin;   Drug: Clopidogrel;   Drug: Prasugrel;   Drug: Ticagrelor
Sponsors:   MJM Bonten;   Australian and New Zealand Intensive Care Research Centre;   Medical Research Institute of New Zealand;   Unity Health;   Berry Consultants;   Global Coalition for Adaptive Research;   University of Pittsburgh Medical Center
Recruiting

Wed, 13 Apr 2016 12:00:00 EDT

The Impact of Vitamins and Minerals Supplementation on Neuropathy and Nephropathy Complications

Condition:   Type 2 Diabetes
Intervention:   Dietary Supplement: vitamin and mineral supplementation
Sponsor:   Shahid Beheshti University of Medical Sciences
Completed

Mon, 02 Aug 2010 12:00:00 EDT

Bioavailability and Pharmacokinetics of Mango

Condition:   Healthy Subjects
Interventions:   Dietary Supplement: Active Comparator 1;   Dietary Supplement: Active Comparator 2;   Dietary Supplement: Control Comparator
Sponsor:   Clinical Nutrition Research Center, Illinois Institute of Technology
Completed

Thu, 07 Dec 2017 12:00:00 EST

Nitric Oxide Bioavailability in Chronic Obstructive Pulmonary Disease (COPD)

Condition:   Pulmonary Disease, Chronic Obstructive
Interventions:   Drug: Tetrahydrobiopterin (BH4);   Dietary Supplement: Antioxidant Cocktail
Sponsors:   Augusta University;   American Heart Association
Completed

Thu, 21 Jul 2011 12:00:00 EDT

Intraoperative Use of Dexketoprofen Trometamol, Pethidine Hcl, Tramadol Hcl and Their Combinations for Postoperative Pain Management in Laparoscopic Nissen Fundoplication

Condition:   Laparoscopic Nissen Fundoplication
Interventions:   Drug: dexketoprofen trometamol;   Drug: tramadol hydrochloride;   Drug: pethidine hydrochloride;   Drug: dexketoprofen trometamol + tramadol hydrochloride;   Drug: dexketoprofen trometamol + pethidine hydrochloride;   Drug: vitamin c
Sponsor:   Kavaklıdere Umut Hospital
Unknown status

Tue, 20 Mar 2012 12:00:00 EDT

Prenatal Multi-micronutrient Supplementation and Pregnancy Outcome

Conditions:   Pregnancy;   Birth Weight
Interventions:   Dietary Supplement: multi micronutrient supplement;   Dietary Supplement: MN1;   Dietary Supplement: MN2
Sponsors:   Bandim Health Project;   Royal Veterinary and Agricultural University, Denmark
Completed

Thu, 15 Sep 2005 12:00:00 EDT

Proflaxis Using Hydroxychloroquine Plus Vitamins-Zinc During COVID-19 Pandemia

Conditions:   Pneumonitis;   Coronavirus Infection
Intervention:   Drug: Plaquenil 200Mg Tablet
Sponsor:   Istinye University
Active, not recruiting

Mon, 30 Mar 2020 12:00:00 EDT

Effect on Migraine Frequency of Combined Anti-oxidant Therapy: The MIGRANT Study.

Condition:   Migraine, Headaches
Intervention:   Drug: N-acetyl cysteine 600 mg, VitE 250 IU, VitC 500 mg tablet
Sponsor:   University of Notre Dame Australia
Unknown status

Mon, 14 Dec 2015 12:00:00 EST

The Impact of Supplementation With Novel Prototype Nutrition Bar on Nitric Oxide Bioavailability and Measures of Athlete Performance

Condition:   Exercise Performance
Interventions:   Other: Active Nitrate Bar;   Other: Placebo Bar
Sponsor:   PepsiCo Global R&D
Completed

Thu, 27 Sep 2018 12:00:00 EDT

COVID-19 Disease Duration and GIT Manifestations. A New Disease Severity Classification. An Egyptian Experience

Conditions:   Covid19;   Diarrhea
Intervention:   Drug: Hydroxychloroquine Pill
Sponsor:   Cairo University
Completed

Fri, 18 Sep 2020 12:00:00 EDT

Efficacy of Psidii Guava's Extract For COVID-19

Condition:   Covid19
Interventions:   Drug: Extract Psidii guava;   Combination Product: Standard therapy for Covid-19 patient
Sponsor:   Faculty of Medicine Baiturrahmah University
Completed

Tue, 23 Mar 2021 12:00:00 EDT

Safety and Efficacy of Hydroxychloroquine for the Treatment & Prevention of Coronavirus Disease 2019 (COVID-19) Caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)

Conditions:   Covid19;   SARS (Severe Acute Respiratory Syndrome)
Interventions:   Drug: Hydroxychloroquine;   Dietary Supplement: Vitamins and Minerals;   Drug: Azithromycin
Sponsor:   International Brain Research Foundation
Not yet recruiting

Mon, 19 Oct 2020 12:00:00 EDT

1064-nm Q-switched Nd:YAG Laser and Intradermal Tranexamic Acid for Melasma

Condition:   Melasma
Interventions:   Procedure: intradermal tranexamic acid;   Device: Nd-YAG
Sponsor:   Taipei Medical University WanFang Hospital
Unknown status

Mon, 02 Jan 2017 12:00:00 EST

Polyphenols in Sorghum and Iron Absorption

Condition:   Iron Absorption in Presence of Polyphenols
Intervention:   Dietary Supplement: labeled iron solutions
Sponsor:   Swiss Federal Institute of Technology
Completed

Wed, 14 Jul 2010 12:00:00 EDT

Preventive Treatment of Pain After Dental Implant Surgery

Condition:   Acute Pain
Interventions:   Drug: DEXKETOPROFEN TROMETAMOL;   Other: Placebo
Sponsors:   Universidad de Murcia;   Mozo Grau Ticare
Completed

Tue, 11 Apr 2017 12:00:00 EDT

Pik Lenin High Altitude Research Expedition 2009

Conditions:   Oxidative Stress;   Cell-derived Microparticles
Interventions:   Dietary Supplement: antioxidant supplements;   Dietary Supplement: Placebo
Sponsors:   University Hospital Inselspital, Berne;   Kantonsspital Aarau;   Lotteriefonds des Kantons Aarau;   Schweizer Gesellschaft für Gebirgsmedizin;   University of Bern
Completed

Thu, 05 Apr 2012 12:00:00 EDT

Outpatient Cervical Ripening With Orally Administered Misoprostol in Diabetics

Condition:   Diabetes, Gestational
Interventions:   Drug: Misoprostol;   Dietary Supplement: Placebo
Sponsors:   University of California, Irvine;   Long Beach Memorial Medical Center
Terminated

Fri, 10 Aug 2007 12:00:00 EDT

Comparison of Redermic, Rejuva-A and Combination of Both Redermic and Rejuva-A in Subjects With Signs of Aging

Condition:   Skin Aging
Interventions:   Other: Redermic;   Drug: Tretinoin (Rejuva-A)
Sponsors:   Cosmetique Active International;   Innovaderm Research Inc.
Completed

Thu, 10 Sep 2009 12:00:00 EDT

Antioxidant Therapy in Lean and Obese Asthmatics

Condition:   Asthma
Interventions:   Dietary Supplement: Vitamins A, E, C & Selenium;   Dietary Supplement: Placebo
Sponsors:   Nemours Children's Clinic;   American Lung Association
Completed

Thu, 17 Mar 2011 12:00:00 EDT

Trial of Vitamins Among Children of HIV-infected Women

Conditions:   HIV Infections;   Pregnancy Complications
Interventions:   Drug: Multivitamins - vitamins B complex, C and E;   Drug: Placebo
Sponsors:   Harvard School of Public Health;   Muhimbili University of Health and Allied Sciences
Completed

Tue, 20 Sep 2005 12:00:00 EDT

Investigating the Acute Effects of Flavonoids in Blueberries on Cognitive Function.

Condition:   Healthy Adults.
Interventions:   Dietary Supplement: Flavonoids;   Dietary Supplement: Control
Sponsor:   University of Reading
Completed

Fri, 04 Feb 2011 12:00:00 EST

Oral Iron vs. Placebo in Newly Diagnosed Gynecologic Oncology Patients Who Are Surgical Candidates.

Conditions:   Ovarian Cancer;   Cervical Cancer;   Uterine Cancer;   Anemia
Interventions:   Other: Oral Ferrous Fumarate;   Other: Placebo
Sponsor:   Sunnybrook Health Sciences Centre
Completed

Mon, 30 Sep 2013 12:00:00 EDT

Investigating Pathways Between Maternal Nutritional Status, Breastmilk Composition, and Infant Linear Growth in Rural Pakistan

Conditions:   Breast Milk Collection;   Infant Development
Intervention:   Dietary Supplement: Multiple micronutrients (UNIMMAP composition)
Sponsors:   Aga Khan University;   The Hospital for Sick Children;   University of Toronto
Completed

Tue, 30 Jun 2020 12:00:00 EDT

Aloe Vera in Irritable Bowel Syndrome

Condition:   Irritable Bowel Syndrome
Interventions:   Dietary Supplement: Aloe vera effervescent tablet (AVH200);   Dietary Supplement: Placebo control
Sponsors:   Sahlgrenska University Hospital, Sweden;   Calmino group AB
Completed

Fri, 22 Jul 2011 12:00:00 EDT

Antioxidants vs. Ovarian Bio-stimulation Therapy to Rescue the Ovarian Reserve

Condition:   Ovarian Reserve
Interventions:   Procedure: blood rich plasma platelets;   Dietary Supplement: Antioxidant therapy
Sponsor:   Lucy Coleman
Completed

Wed, 08 Aug 2018 12:00:00 EDT

Cure Rates of Superficial Basal Cell Carcinoma (BCC) EDC

Condition:   Superficial Basal Cell Carcinoma
Intervention:   Procedure: Electrodessication & Curettage
Sponsors:   University of Wisconsin, Madison;   Skin Cancer Foundation;   Dermatology Foundation
Terminated

Wed, 14 Oct 2009 12:00:00 EDT

Examining the Effect of Mental Health Disorders on Vascular Function and Exercise Tolerance

Condition:   Mental Health Disorders
Interventions:   Dietary Supplement: PTSD/GAD Antioxidant;   Dietary Supplement: PTSD/GAD Placebo;   Dietary Supplement: Healthy Control Antioxidant;   Dietary Supplement: Healthy Control Placebo
Sponsor:   Virginia Commonwealth University
Completed

Thu, 13 Jul 2017 12:00:00 EDT

Beneficial Effects of Quercetin in Chronic Obstructive Pulmonary Disease (COPD)

Condition:   Chronic Obstructive Pulmonary Disease
Interventions:   Drug: Quercetin;   Other: Placebo - sugar chew
Sponsors:   University of Michigan;   National Institutes of Health (NIH);   Quercegen Pharmaceuticals;   National Center for Complementary and Integrative Health (NCCIH)
Completed

Tue, 16 Oct 2012 12:00:00 EDT

A Clinical Trial Evaluating the Effect of Pharmacological Ascorbate on Radiation Therapy for Pancreatic Cancer Patients

Condition:   Pancreatic Neoplasm
Interventions:   Drug: Ascorbate;   Drug: Gemcitabine;   Radiation: radiation therapy
Sponsors:   Joseph J. Cullen;   Holden Comprehensive Cancer Center
Not yet recruiting

Wed, 30 May 2018 12:00:00 EDT

Understanding the Exercise-Hypertension Paradox

Condition:   Hypertension
Interventions:   Dietary Supplement: Oral Antioxidant;   Other: Exercise rehabilitation
Sponsor:   VA Office of Research and Development
Recruiting

Mon, 13 Jan 2014 12:00:00 EST

Evaluation of Zinc and / or Micronutrient Supplementation on Intestinal Flora, Diarrheal Disease Burden, Intestinal Mucosal Integrity and Growth Among Children of Pakistan

Conditions:   Malnutrition;   Diarrhea;   Pneumonia;   Growth
Interventions:   Dietary Supplement: Micronutrient Supplementation without Zinc;   Dietary Supplement: Micronutrient Supplementation with Zinc;   Other: Nutritional Counselling and Education
Sponsors:   Aga Khan University;   Bill and Melinda Gates Foundation;   Tufts University
Completed

Thu, 26 Jun 2008 12:00:00 EDT

Plant Sterol INtervention for Cancer Prevention (PINC)

Conditions:   Hypercholesterolemia;   Breast Cancer;   Obesity
Interventions:   Dietary Supplement: Cholesterol Reducing Strawberry Yogurt Drink (Tesco Ltd);   Dietary Supplement: Low Fat Strawberry Yogurt Drinks (Morrisons Ltd)
Sponsors:   University of Leeds;   The Leeds Teaching Hospitals NHS Trust;   University of Oslo
Recruiting

Fri, 01 Nov 2019 12:00:00 EDT

Effect of Nutrition Ingredients on Microbiota Modulation

Condition:   Healthy Volunteers
Interventions:   Dietary Supplement: Vitamin B2;   Dietary Supplement: Vitamin C;   Dietary Supplement: Vitamin B2 + C;   Dietary Supplement: Vitamin A;   Dietary Supplement: Vitamin D3;   Dietary Supplement: Vitamin E;   Dietary Supplement: Placebo
Sponsors:   DSM Nutritional Products, Inc.;   Atlantia Food Clinical Trials
Completed

Thu, 13 Sep 2018 12:00:00 EDT

Quercetin PK/PD Study in Healthy Adults and Patients With Hypercoagulable States

Condition:   Healthy
Intervention:   Drug: isoquercetin or quercetin
Sponsor:   Beth Israel Deaconess Medical Center
Completed

Wed, 07 Nov 2012 12:00:00 EST

Probiotic and Gastrointestinal Symptoms Due to Menstruation in Healthy Women

Condition:   Menstrual Discomfort
Interventions:   Dietary Supplement: Probiotic;   Dietary Supplement: Placebo
Sponsors:   University of Florida;   Lallemand Health Solutions
Recruiting

Tue, 07 Jul 2020 12:00:00 EDT

Coronary Chronic Total Occlusion and Oxidative Balance

Conditions:   Progression of Atherosclerotic Plaque;   Coronary Artery Disease
Intervention:   Diagnostic Test: Comparison of oxidative and antioxidative markers between groups
Sponsor:   Kahramanmaras Sutcu Imam University
Completed

Mon, 15 Feb 2021 12:00:00 EST

Efficacy of Ubiquinone and Combined Antioxidant Therapy in Non-proliferative Diabetic Retinopathy

Conditions:   Non-proliferative Diabetic Retinopathy;   Diabetes Mellitus Type 2
Interventions:   Drug: Ubiquinone;   Drug: Combined antioxidant therapy;   Drug: Placebo
Sponsors:   University of Guadalajara;   Instituto Mexicano del Seguro Social
Completed

Thu, 13 Feb 2014 12:00:00 EST

Probiotics in Women With Primary Dysmenorrhoea

Condition:   Primary Dysmenorrhea
Interventions:   Biological: Probiotic;   Other: Placebo
Sponsors:   National University of Malaysia;   B-Crobes Marketing(M) Sdn Bhd
Completed

Tue, 08 Oct 2019 12:00:00 EDT

The Effect of Probiotic Intake on Intestinal Permeability in Healthy Adults

Condition:   Intestinal Barrier Function
Interventions:   Dietary Supplement: Probiotic;   Dietary Supplement: Placebo
Sponsors:   University of Florida;   Lallemand Health Solutions
Completed

Thu, 02 Aug 2018 12:00:00 EDT

Individualized Bowel Preparation for Colonoscopy

Condition:   Colon Disease
Interventions:   Drug: Standard Preparation;   Drug: Individualized Preparation
Sponsor:   Clinical Hospital Colentina
Unknown status

Mon, 12 Feb 2018 12:00:00 EST

Broccoli Sulforaphane Bioavailability With Mustard

Condition:   Sulforaphane Bioavailability
Interventions:   Dietary Supplement: Broccoli seed extract;   Dietary Supplement: Broccoli seed extract with mustard seed powder
Sponsors:   Appalachian State University;   Brassica Foundation for Chemoprotection Research
Not yet recruiting

Thu, 01 Jul 2021 12:00:00 EDT

Effects of Oral Antioxidant Cocktail in Cardiovascular Disease Patients

Condition:   Cardiovascular Diseases
Interventions:   Dietary Supplement: Oral antioxidant cocktail;   Other: Baseline
Sponsor:   University of Nebraska
Recruiting

Tue, 14 Aug 2018 12:00:00 EDT

Folic Acid for Vascular Outcome Reduction In Transplantation (FAVORIT)

Conditions:   Chronic Kidney Disease;   Cardiovascular Disease;   Death
Interventions:   Drug: High Dose Multivitamin;   Device: Low Dose Multivitamin
Sponsors:   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK);   Office of Dietary Supplements (ODS)
Completed

Tue, 15 Jul 2003 12:00:00 EDT

Comparison Between 2L Coolprep® and Combination of 1L Coolprep® and Bisacodyl as Bowel Preparation

Conditions:   Healthy Person;   Bowel Preparation Before Colonoscopy
Interventions:   Drug: 2L Coolprep®;   Drug: 1L Coolprep® and Bisacodyl
Sponsor:   Seoul National University Hospital
Completed

Mon, 10 Dec 2012 12:00:00 EST

Comparison of the Effectiveness of Bowel Preparations Before Colonoscopy

Condition:   Colorectal Neoplasms
Intervention:   Procedure: colonoscopy
Sponsors:   Military University Hospital, Prague;   Masaryk University
Unknown status

Tue, 08 Aug 2017 12:00:00 EDT

Retrospective Study of ImmunoFormulation for COVID-19

Condition:   Covid19
Intervention:   Dietary Supplement: ImmunoFormulation
Sponsor:   Fagron Iberica S.A.U.
Completed

Mon, 14 Dec 2020 12:00:00 EST

Soy Modulation of Immune Activation, LDL- Levels, and Lowering Inflammation by Pretzel Isoflavone Dietary Intervention

Conditions:   Human Immunodeficiency Virus (HIV) Infection;   Hypercholesterolemia
Interventions:   Other: Soy Pretzel;   Other: Wheat Pretzel
Sponsor:   Ohio State University
Recruiting

Wed, 29 Jun 2016 12:00:00 EDT

Prenatal Iodine Supplementation and Early Childhood Neurodevelopment

Conditions:   Pregnancy Related;   Neurodevelopmental Disorders;   Nutrition Disorder, Fetal
Interventions:   Combination Product: Low Iodine Supplement;   Combination Product: Standard Iodine Supplement
Sponsors:   South Australian Health and Medical Research Institute;   Women's and Children's Hospital, Australia;   Flinders Medical Centre;   Mater Mothers' Hospital;   The Royal Women's Hospital;   Royal North Shore Hospital
Recruiting

Wed, 14 Oct 2020 12:00:00 EDT

The Effect of 12-week Dietary Intake of Food Supplements Containing Collagen on Dermis Density and Other Skin Parameters

Conditions:   Dermis Density;   Wrinkles;   Skin Hydration;   Trans Epidermal Water Loss (TEWL);   Dermis Thickness;   Skin Texture;   Skin Elasticity
Interventions:   Dietary Supplement: Investigational product 1;   Dietary Supplement: Placebo syrup;   Dietary Supplement: Investigational product 2;   Dietary Supplement: Investigational product 3
Sponsors:   Higher School of Applied Sciences (VIST);   Tosla d.o.o.;   Slovenian Research Agency
Recruiting

Tue, 03 Aug 2021 12:00:00 EDT

Brain Connectivity in Attention Deficit Hyperactivity Disorder (ADHD)

Condition:   Attention Deficit Hyperactivity Disorder (ADHD)
Intervention:   Drug: MPH
Sponsors:   King's College London;   Shire
Completed

Wed, 17 Oct 2018 12:00:00 EDT

Evaluation of Strategies for Improved Uptake of Preventive Treatment for Intestinal Schistosomiasis

Condition:   Schistosomiasis
Interventions:   Other: Pre-treatment snack;   Behavioral: Education arm
Sponsors:   Makerere University;   University of Copenhagen
Unknown status

Wed, 05 Jun 2013 12:00:00 EDT

Yeast Cells as Antioxidant-Producing Probiotics

Condition:   Infertility, Male
Interventions:   Dietary Supplement: Vit E 1;   Dietary Supplement: Vit E 2;   Dietary Supplement: Vit E 3;   Dietary Supplement: YE 1;   Dietary Supplement: YE 2;   Dietary Supplement: YE 3;   Dietary Supplement: Vit C 1;   Dietary Supplement: Vit C 2;   Dietary Supplement: Vit C 3
Sponsors:   Benha University;   Hawaa Fertility Center;   Zagazig University
Completed

Tue, 28 Jun 2016 12:00:00 EDT

Impact of Time Intervals of Preparation on Quality and Tolerance of the Bowel Preparation

Conditions:   Bowel Preparation;   Colonoscopy
Intervention:   Procedure: Colonoscopy
Sponsors:   Faculty Hospital Kralovske Vinohrady;   Nemocnice T.Bati, Zlin;   Brno University Hospital;   University Hospital, Motol
Unknown status

Wed, 21 Sep 2016 12:00:00 EDT

Study of Supplement's Antioxidant Properties That Contains Natural Extracts

Condition:   Healthy
Interventions:   Dietary Supplement: Mind Master;   Dietary Supplement: Placebo
Sponsor:   Harokopio University
Unknown status

Tue, 19 Jul 2016 12:00:00 EDT

Theranostic Implication of Complementary Medicines Against Interleukin Receptors and Gp-130 Proteins

Condition:   Corona Virus Disease 2019 (COVID-19)
Intervention:   Drug: Tocilizumab
Sponsor:   University of Lahore
Completed

Thu, 31 Dec 2020 12:00:00 EST

Amino Acid Chelated Iron Versus Ferrous Fumarate in the Treatment of Iron Deficiency Anemia With Pregnancy: Randomized Controlled Trial

Condition:   Iron Deficiency Anemia
Interventions:   Drug: Amino Acid chelated iron tab 15 mg;   Drug: Ferrous Fumarate tab 350 mg( 115 mg elemental iron)
Sponsor:   Ain Shams University
Unknown status

Tue, 05 Feb 2019 12:00:00 EST

A Trial of Zinc and Micronutrients in Tanzanian Children

Conditions:   Diarrheal Illnesses;   Respiratory Illness;   Growth Faltering
Interventions:   Drug: Zinc;   Drug: Multivitamins;   Drug: Placebo
Sponsors:   Harvard School of Public Health;   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Completed

Fri, 12 Jan 2007 12:00:00 EST

A Pharmacokinetic Study of NER1006 in Healthy Subjects

Condition:   Pharmacokinetic
Intervention:   Drug: NER1006 powder for oral solution
Sponsors:   Norgine;   Quotient Clinical
Completed

Mon, 19 Feb 2018 12:00:00 EST

Study of Prevalence and Risk Factors of Hypovitaminosis C in Long Term Care Unit

Conditions:   Vitamin C Deficiency;   Scurvy
Intervention:   Procedure: Blood sample
Sponsor:   Hospices Civils de Lyon
Completed

Thu, 17 Jan 2019 12:00:00 EST

AvidinOX + [177Lu]DOTA-biotin (or 177Lu-ST2210) Complex in Patients With Liver Metastases From Colorectal Cancer

Condition:   Liver Metastases
Intervention:   Combination Product: AvidinOX/ST2210
Sponsor:   Alfasigma S.p.A.
Terminated

Mon, 03 Feb 2014 12:00:00 EST

Women's Angiographic Vitamin and Estrogen Trial (WAVE)

Conditions:   Cardiovascular Diseases;   Coronary Arteriosclerosis;   Coronary Disease;   Heart Diseases;   Myocardial Ischemia;   Postmenopause
Interventions:   Drug: estrogen replacement therapy;   Drug: estrogens, conjugated;   Drug: progesterone;   Drug: hormone replacement therapy;   Drug: supplementation, food;   Drug: ascorbic acid;   Drug: vitamin e
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Completed

Thu, 28 Oct 1999 12:00:00 EDT

Randomized Double Blind Placebo Controlled Clinical Trial to Evaluate Obese and Overweight Subjects

Condition:   Weight Loss
Interventions:   Drug: Polyglucosamine L112;   Other: Placebo
Sponsor:   Certmedica International GmbH
Enrolling by invitation

Tue, 05 May 2020 12:00:00 EDT

Short-term Outcomes of Full Bowel Preparation (MBP+OA) for Rectal Resections for Cancer Versus MBP Alone

Condition:   Rectal Cancer
Interventions:   Procedure: Full bowel preparation;   Procedure: Mechanical bowel preparation only
Sponsor:   N.N. Petrov National Medical Research Center of Oncology
Recruiting

Mon, 19 Oct 2020 12:00:00 EDT

Single Center Comparison of 4 FDA Approved, Commercially Available Bowel Purgatives for Colonoscopy

Condition:   Patients Undergoing Screening or Surveillance Colonoscopy
Interventions:   Drug: PEG+E;   Drug: PEG+Asc;   Drug: P+MC;   Drug: sulfate
Sponsor:   Medical College of Wisconsin
Withdrawn

Mon, 28 Apr 2014 12:00:00 EDT

Treatment of Dry Eye With Supplements

Condition:   Dry Eye Syndromes
Intervention:   Dietary Supplement: Vitamac® Tag and Nacht capsules
Sponsor:   Medical University of Vienna
Withdrawn

Thu, 02 Jun 2011 12:00:00 EDT

A Randomized Prospective Trial Comparing Low-volume Bowel Preparation Methods

Conditions:   Colorectal Cancer;   Colon Adenoma
Interventions:   Drug: PEG-Asc;   Drug: SPMC 2
Sponsor:   Korea University Anam Hospital
Completed

Fri, 26 Sep 2014 12:00:00 EDT

The Effect of Platelet-Rich Plasma-Fibrin Glue in Combination With Vitamin E and C for Treatment of Non-healing Diabetic Foot Ulcers

Conditions:   Diabetic Foot Ulcers;   Diabetic Wound
Interventions:   Drug: PRP-Fibrin Glue;   Dietary Supplement: Vitamin E and C;   Other: Placebo
Sponsor:   Mashhad University of Medical Sciences
Recruiting

Fri, 20 Mar 2020 12:00:00 EDT

Fibroids in Women of Reproductive Age and Women Pregnancy

Condition:   Fibroids
Interventions:   Drug: Dydrogesterone M ( case 1 );   Drug: Dydrogesterone M ( case 2 )
Sponsor:   Trieu, Nguyen Thi, M.D.
Completed

Thu, 03 Dec 2015 12:00:00 EST

Burn Micronutrient Repletion Pilot Study

Condition:   Burn
Intervention:   Dietary Supplement: Vitamin and Mineral supplementation
Sponsors:   Southern Illinois University;   Memorial Medical Center
Completed

Fri, 10 Apr 2009 12:00:00 EDT

Probiotic and Influenza Vaccination to Reducing Influenza-like Illness Incident in Elderly

Condition:   Influenza-like Illness
Interventions:   Biological: Flubio;   Dietary Supplement: Lacidofil;   Other: Placebo Vaccine;   Other: Placebo probiotic
Sponsor:   Indonesia University
Completed

Thu, 04 Oct 2018 12:00:00 EDT

MEDICO-ECONOMIC EVALUATION OF SURGERY GUIDED BY FLUORESCENCE FOR THE OPTIMIZATION OF RESECTION OF GLIOBLASTOMAS

Condition:   Glioblastoma
Interventions:   Drug: 5-aminolévulinique acid (5-ALA);   Drug: Placebo
Sponsor:   Hospices Civils de Lyon
Unknown status

Thu, 14 Mar 2013 12:00:00 EDT

Improving Gait in Persons With Knee Related Mobility Limitations by Rosenoids® Food Supplement: a Randomized Double-blind Placebo-controlled Trial

Condition:   Knee Related Walking Limitations
Interventions:   Dietary Supplement: Rosehip;   Dietary Supplement: Placebo
Sponsor:   Frederiksberg University Hospital
Completed

Fri, 23 Aug 2013 12:00:00 EDT

To Evaluate Safety and Efficacy of CGBIO Stent Compared to Biomatrix Flex Stent

Conditions:   Ischemic Heart Disease;   Stable Coronary Artery Disease;   Stable Angina;   Unstable Angina;   NSTEMI - Non-ST Segment Elevation MI
Interventions:   Device: CGBio stent;   Device: Biomatrix flex
Sponsor:   CGBio Inc.
Unknown status

Fri, 24 Mar 2017 12:00:00 EDT

Symptomatic Treatment of Common Cold Symptoms

Condition:   Common Cold
Interventions:   Drug: Aspirin (Acetylsalicylic acid, BAYE4465);   Drug: Placebo
Sponsor:   Bayer
Completed

Wed, 16 Dec 2009 12:00:00 EST

Open Label of Clinical Trial of Sulforaphane in Children With Autism

Condition:   Autism
Intervention:   Dietary Supplement: Sulforaphane
Sponsor:   University of California, San Francisco
Completed

Wed, 13 Jan 2016 12:00:00 EST

Efficacy of Probaclac in Irritable Bowel Syndrome in Children Aged 8 to 18 Years

Condition:   Irritable Bowel Syndrome
Interventions:   Other: Probaclac;   Other: Placebo
Sponsors:   St. Justine's Hospital;   Nicar Inc.
Terminated

Wed, 19 Nov 2008 12:00:00 EST

Examining the Impact of Exercise Training on Vascular Dysfunction in Individuals With Mental Health Disorders - Study 1

Condition:   Peripheral Vascular Diseases
Interventions:   Dietary Supplement: Antioxidant;   Dietary Supplement: Placebo
Sponsor:   Virginia Commonwealth University
Recruiting

Mon, 07 Jun 2021 12:00:00 EDT

Effect of Probiotics on Functional Constipation in Adults

Condition:   Functional Constipation
Interventions:   Dietary Supplement: Placebo;   Dietary Supplement: 3 Billion UFC strains of probiotics;   Dietary Supplement: 8 Billion UFC strains of probiotics
Sponsor:   Luciane Cruz Lopes
Completed

Thu, 18 Jun 2020 12:00:00 EDT

Tolerability and Efficacy of RJX in Patients With COVID-19

Conditions:   COVID-19;   Acute Respiratory Distress Syndrome;   SARS-CoV-2;   Hypoxemia
Interventions:   Drug: Rejuveinix (RJX) Active Comparator;   Drug: Placebo Comparator
Sponsor:   Reven Pharmaceuticals, Inc.
Recruiting

Wed, 13 Jan 2021 12:00:00 EST

Evaluation of the Effects of Treatment With Bioarginin C in Adult Subjects Belonging to the Post-Covid Day Hospital

Conditions:   Fatigue Syndrome, Chronic;   Inflammation
Intervention:   Dietary Supplement: Bioarginina C
Sponsor:   University of Milan
Recruiting

Thu, 01 Jul 2021 12:00:00 EDT

The Use of Osmotic Laxatives Versus Macrogol for Bowel Preparation in Patients Undergoing Colonoscopy

Condition:   Colorectal Disorders
Interventions:   Drug: Eziklen®;   Drug: MoviPrep
Sponsor:   Russian Society of Colorectal Surgeons
Recruiting

Mon, 13 Jan 2020 12:00:00 EST

Randomized Trial of Regenexx Stem Cell Support Formula

Condition:   Knee Osteoarthritis
Interventions:   Dietary Supplement: Stem Cell Support Formula;   Dietary Supplement: Placebo
Sponsor:   Regenexx, LLC
Recruiting

Thu, 10 Dec 2020 12:00:00 EST

Patient and Colonoscopy Cleansing Quality Agreement

Condition:   Cleansing Quality of the Colon
Interventions:   Drug: Bowel preparation before colonoscopy;   Procedure: Colonoscopy
Sponsor:   Hospital Universitario de Canarias
Recruiting

Mon, 11 Jan 2021 12:00:00 EST

Impact of HLNatural Immune Supplement on Colds

Condition:   Immune System Diseases
Intervention:   Dietary Supplement: HLNatural Immune
Sponsors:   Hawthorne Effect Inc.;   HLNatural, Inc.
Unknown status

Wed, 25 Sep 2019 12:00:00 EDT

Efficacy Trial to Examine Efficacy of Multimicronutrient Home Supplementation in Infants

Conditions:   Iron Deficiency Anemia;   Infectious Diseases;   Undernutrition
Interventions:   Dietary Supplement: Sprinkles;   Dietary Supplement: Ferripel-3, Vitamins A&D drops
Sponsor:   Soroka University Medical Center
Completed

Fri, 13 Jan 2006 12:00:00 EST

EUROPAC-2 - Pain Treatment of Hereditary and Idiopathic Pancreatitis

Condition:   Pancreatitis
Interventions:   Dietary Supplement: ANTOX (vers.)1.2;   Drug: Magnesium;   Other: Placebo ANTOX (vers)1.2;   Other: Placebo Magnesiocard (2.5 mmol)
Sponsor:   University Medicine Greifswald
Completed

Fri, 02 Sep 2005 12:00:00 EDT

NBF Gingival Gel Application After Impacted Lower Third Molar Surgery

Condition:   Alveolar Osteitis
Interventions:   Drug: NBF;   Device: Placebo
Sponsors:   Universidad Complutense de Madrid;   Bio Nature Essences S.L
Completed

Wed, 22 Aug 2018 12:00:00 EDT

Combined Antioxidant Therapy on Oxidative Stress in Aqueous and Vitreous Humor of Diabetic Retinopathy Patients

Conditions:   Diabetic Retinopathy;   Oxidative Stress;   Diabetes
Interventions:   Drug: Combined antioxidant therapy;   Other: Placebo
Sponsors:   University of Guadalajara;   Hospital Civil de Guadalajara
Recruiting

Wed, 28 Aug 2019 12:00:00 EDT

Combined Antioxidant Therapy on Oxidative Stress, Mitochondrial Dysfunction Markers in Diabetic Retinopathy

Condition:   Diabetic Retinopathy
Interventions:   Drug: Combined antioxidant therapy;   Other: Placebo
Sponsors:   University of Guadalajara;   Instituto Mexicano del Seguro Social
Recruiting

Thu, 11 Oct 2018 12:00:00 EDT

Safety and Immunogenicity of Peru-15 Vaccine When Given With Measles Vaccine in Healthy Indian and Bangladeshi Infants

Conditions:   Cholera;   Diarrhea;   Vibrio Infections
Interventions:   Biological: Peru-15 Vaccine;   Biological: Placebo
Sponsors:   International Vaccine Institute;   International Centre for Diarrhoeal Disease Research, Bangladesh;   Christian Medical College, Vellore, India;   Avant Immunotherapeutics;   Vaccine Technologies Inc.
Terminated

Thu, 28 Feb 2008 12:00:00 EST

Anti-Oxidant Supplementation for the Prevention of Acute Mountain Sickness

Condition:   Acute Mountain Sickness
Interventions:   Dietary Supplement: Anti-oxidant supplementation;   Dietary Supplement: Matched placebo for anti-oxidant supplementation
Sponsors:   Altitude Physiology Expeditions;   University of Edinburgh
Completed

Tue, 22 Apr 2008 12:00:00 EDT

Study of Docosahexanoic Acid in Patients With Cystic Fibrosis (CF)

Condition:   Cystic Fibrosis
Interventions:   Drug: Docosahexaenoic acid;   Drug: Sunflower Oil
Sponsor:   Hospices Civils de Lyon
Completed

Wed, 24 Feb 2016 12:00:00 EST

The Effect of Combinatorial Nutritional Supplementation on Immune Function in Healthy Older Adults

Condition:   Vitamin D Deficiency
Interventions:   Dietary Supplement: Redoxon VI;   Dietary Supplement: placebo
Sponsor:   Oregon State University
Active, not recruiting

Tue, 23 Aug 2016 12:00:00 EDT

Functional Snack Foods With Safflower Oil and Soy in Postmenopausal Women Having Metabolic Syndrome

Conditions:   Metabolic Syndrome;   Overweight
Interventions:   Other: wheat-safflower oil pretzels;   Other: soy-safflower oil pretzels;   Other: control wheat pretzels
Sponsor:   Ohio State University
Active, not recruiting

Thu, 24 Jul 2014 12:00:00 EDT

Glutathione Metabolism in Adolescents With Type 1 Diabetes - Study B

Condition:   Diabetes Mellitus, Type 1
Interventions:   Dietary Supplement: Antioxidant supplement;   Other: Diabetes treatment;   Drug: Regular Insulin
Sponsors:   Nemours Children's Clinic;   Juvenile Diabetes Research Foundation
Completed

Mon, 09 Mar 2009 12:00:00 EDT

Investigation of Macular Pigment Augmentation on Dark Adaptation

Conditions:   Aging;   Age-Related Macular Degeneration
Interventions:   Dietary Supplement: ZeaVision EyePromise Restore;   Dietary Supplement: Multivitamin
Sponsors:   University of Alabama at Birmingham;   ZeaVision, Inc.
Terminated

Thu, 24 May 2007 12:00:00 EDT

Combined Vitamins and Minerals Decrease Incidence of Upper Respiratory Tract Infections in Older Persons

Condition:   Upper Respiratory Tract Infection
Interventions:   Dietary Supplement: daily multi micronutrient supplement;   Dietary Supplement: Placebo
Sponsor:   Trisakti University
Completed

Fri, 02 Dec 2011 12:00:00 EST

Propolis Extract, Nanovitamin C and Nanovitamin E in Peri-implant Mucositis

Condition:   Peri-implant Mucositis
Interventions:   Device: Gel containing propolis extract, nanovitamin C and nanovitamin E;   Device: Placebo
Sponsors:   Universidad Complutense de Madrid;   Bio Nature Essences S.L
Completed

Thu, 02 Jan 2020 12:00:00 EST

Effects Antioxidants Supplementation on Muscular Function Patients Facioscapulohumeral Dystrophy (FSHD)

Condition:   Facioscapulohumeral Muscular Dystrophy
Interventions:   Procedure: Taking of blood;   Dietary Supplement: needle biopsy of the vastus lateralis muscle;   Dietary Supplement: Vit C Vit E Zn Se;   Dietary Supplement: Placebo Vit E Placebo Vit C Zn Se
Sponsors:   University Hospital, Montpellier;   Hospital Clinical Research Project 2010;   Association Amis FSH France;   FSH Dutch Fondation The Netherland
Completed

Fri, 11 May 2012 12:00:00 EDT

Fixed Dose Flavonoid Isoquercetin on Thrombo-Inflammatory Biomarkers in Subjects With Stable Sickle Cell Disease

Condition:   VTE
Interventions:   Drug: Isoquercetin;   Drug: Placebo
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting

Mon, 17 Aug 2020 12:00:00 EDT

Hexetidine and Chlorobutanol for Lesions Due to Prostheses

Condition:   Oral Mucositis
Interventions:   Drug: chlorobutanol, hexetidine;   Drug: Chlorhexidine
Sponsor:   Federico II University
Completed

Mon, 03 May 2010 12:00:00 EDT

The Safety and Efficacy of a Compound Natural Health Product in Children With Attention Deficit Hyperactivity Disorder (ADHD)

Condition:   Attention Deficit Hyperactivity Disorder
Interventions:   Dietary Supplement: Compound Natural Health Product;   Dietary Supplement: Placebo
Sponsors:   The Canadian College of Naturopathic Medicine;   Health Canada;   Centre for Addiction and Mental Health;   SickKids Foundation
Completed

Tue, 01 Dec 2009 12:00:00 EST

Metabolism And Health Effects Of Citrus Limonoids in Hypercholesterolemic Humans

Condition:   Hypercholesterolemia
Interventions:   Dietary Supplement: Citrus Limonoid Beverage;   Dietary Supplement: Placebo beverage
Sponsors:   USDA, Western Human Nutrition Research Center;   The Beverage Institute for Health & Wellness;   United States Department of Agriculture (USDA)
Completed

Fri, 13 Dec 2013 12:00:00 EST

Treatment of HFpEF With Nitrate Supplement

Condition:   Heart Failure With Normal Ejection Fraction
Interventions:   Dietary Supplement: Active lozenge;   Drug: Placebo
Sponsors:   MaineHealth;   HumanN
Completed

Thu, 21 Sep 2017 12:00:00 EDT

Blood Antioxidant Status in Chronic Hepatitis C Patients Before and After Antioxidant Supplementation: a Randomized Clinical Trial

Conditions:   Hepatitis C;   Oxidative Stress
Intervention:   Dietary Supplement: Antioxidant Supplementation
Sponsor:   Universidade do Sul de Santa Catarina
Completed

Wed, 23 Sep 2009 12:00:00 EDT

Cystic Fibrosis and Endothelial Function: At Rest and During Exercise

Condition:   Cystic Fibrosis
Interventions:   Drug: BH4 5mg;   Drug: BH4 20mg;   Dietary Supplement: Antioxidant Cocktail
Sponsor:   Augusta University
Completed

Mon, 21 Jan 2013 12:00:00 EST

Efficacy and Tolerability of a Nutritional Supplement, Plactive Progen, in ACL Reconstruction

Condition:   ACL Reconstruction
Intervention:   Dietary Supplement: PROGEN
Sponsor:   OPKO Health, Inc.
Completed

Tue, 28 Nov 2017 12:00:00 EST

Observational Study With Mode of Action-Analysis of Cystorenal Cranberry Extract in Patients With Recurrent Urinary Tract Infections

Condition:   Urinary Tract Infections
Intervention:   Dietary Supplement: Cranberry Extract
Sponsor:   Charite University, Berlin, Germany
Completed

Fri, 13 Jan 2017 12:00:00 EST

The Effects of Bifidobacterium Breve Bif195 for Small Intestinal Crohn's Disease

Condition:   Crohn Disease
Interventions:   Dietary Supplement: Bif195 capsules;   Dietary Supplement: Placebo capsules
Sponsors:   Hvidovre University Hospital;   Chr Hansen
Recruiting

Tue, 13 Apr 2021 12:00:00 EDT

The Effects of Bifidobacterium Breve Bif195 for Diarrhea-predominant Irritable Bowel Syndrome

Condition:   Irritable Bowel Syndrome
Interventions:   Dietary Supplement: Bifidobacterium breve Bif195;   Dietary Supplement: Placebo
Sponsors:   Hvidovre University Hospital;   Chr Hansen
Recruiting

Mon, 22 Mar 2021 12:00:00 EDT

Role of Human Leukocyte Antigen Matching in Liver Transplantation and Its Relation to Outcomes

Condition:   Liver Transplantation
Intervention:   Diagnostic Test: HLA cross matching
Sponsor:   Ain Shams University
Completed

Wed, 29 Mar 2017 12:00:00 EDT

Health Related Quality of Life Assessment In Egyptian Recipients After Living Donor Liver Transplantation

Condition:   Health Related Quality of Life
Intervention:  
Sponsor:   Ain Shams University
Completed

Wed, 06 Feb 2013 12:00:00 EST

Treatment of Schizophrenia With an Omega-3 Fatty Acid (EPA) and Antioxidants

Conditions:   Schizophrenia;   Schizophreniform Disorders;   Schizoaffective Disorder;   Psychotic Disorders
Interventions:   Drug: Ethyl-eicosapentaenoic acid (EPA);   Drug: Vitamins E + C;   Other: Etyl EPA (placebo);   Other: Vitamins E+C (placebo)
Sponsors:   University Hospital, Aker;   Diakonhjemmet Hospital;   Stanley Medical Research Institute;   Laxdale Ltd;   Scandinavian Society for Psychopharmacology;   Shipowner Emil Stray's legacy;   Johanne and Einar Eilertsen's research fund;   AstraZeneca;   Solveig and Johan P. Sommer's foundation;   Josef and Haldis Andresen's legacy;   University of Oslo;   Norwegian University of Science and Technology
Completed

Mon, 08 Jan 2007 12:00:00 EST

Effects of a Bakery Product Enriched With Fibre and L-carnitine on Insulin Resistance in Patients With Metabolic Syndrome

Conditions:   Metabolic X Syndrome;   Overweight;   Dyslipidemias
Interventions:   Dietary Supplement: dietary fibre plus L-carnitine bread;   Dietary Supplement: Placebo bread
Sponsors:   Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana;   AINIATechnology Center
Completed

Sun, 02 Nov 2014 12:00:00 EDT

Isotretinoin in Treatment of COVID-19

Condition:   COVID-19
Intervention:   Drug: Isotretinoin Only Product in Oral Dose Form
Sponsor:   Tanta University
Not yet recruiting

Fri, 24 Apr 2020 12:00:00 EDT

National Multicentric Observatory of Low Bowel Preparations in Patients With IBD

Condition:   Patient With an Indication of Colonoscopy for Inflammatory Bowel Disease
Intervention:   Procedure: Low volume bowel preparation in inflammatory bowel diseases
Sponsor:   Centre Hospitalier Universitaire de Besancon
Completed

Tue, 27 Nov 2018 12:00:00 EST

Epigenorm Antivir Combined With Acupuncture for the Treatment of Osteoarthritis Patients Who Are Overweight or Obese

Conditions:   Osteoarthritis;   Overweight and Obesity
Interventions:   Dietary Supplement: Epigenorm Antivir;   Procedure: Acupuncture
Sponsor:   Federal State Budgetary Scientific Institution, Research Institute of Fundamental and Clinical Immunology
Unknown status

Wed, 30 May 2018 12:00:00 EDT

Safety and Tolerability of Kiddi® Pharmaton Fizz Effervescent Tablets in Children

Condition:   Healthy
Interventions:   Drug: Kiddi® Pharmaton Fizz, effervescent tablets;   Drug: Kiddi® Pharmaton Fizz, effervescent tablets: marketed formula;   Drug: Comparator product
Sponsor:   Boehringer Ingelheim
Completed

Wed, 09 Jul 2014 12:00:00 EDT

High-dose Antioxidants for Central Serous Chorioretinopathy

Condition:   Central Serous Chorioretinopathy
Intervention:   Drug: antioxidants tablets
Sponsors:   Prince of Songkla University;   Alcon Research
Completed

Fri, 21 Aug 2009 12:00:00 EDT

Home Fortification of Complementary Foods in Bihar India

Conditions:   Anemia;   Malnutrition
Interventions:   Dietary Supplement: Home Fortification Product (HFP);   Other: Infant and Young Child Feeding (IYCF) Practices Counseling
Sponsor:   Emory University
Completed

Fri, 30 Oct 2015 12:00:00 EDT

Analysis of MicroBial Metabolites After Eating Refined Food

Condition:   Dietary Habits
Interventions:   Other: Ultra-processed Food Meal;   Other: Whole Food Meal
Sponsor:   The Cleveland Clinic
Recruiting

Mon, 16 Mar 2020 12:00:00 EDT

Effect of Ileocolonic Delivered Vitamins and an Anti-Inflammatory Diet on Crohn's Disease and Healthy Volunteers

Condition:   Crohn Disease
Interventions:   Other: Groningen Anti-Inflammatory Diet (GrAID);   Dietary Supplement: ColoVit capsule;   Other: ColoPulse-placebo capsule
Sponsor:   University Medical Center Groningen
Not yet recruiting

Fri, 04 Jun 2021 12:00:00 EDT

Probiotic Supplementation and Endurance Performance in Cyclists and Masters Runners

Conditions:   Viral Upper Respiratory Tract Infection;   Gastroenteritis
Interventions:   Dietary Supplement: Probiotics;   Other: Placebo
Sponsor:   Tel Hai College
Completed

Fri, 29 Apr 2016 12:00:00 EDT

Intervention for Multivitamin Adherence on Bariatric Patients

Condition:   Adherence, Medication
Intervention:   Behavioral: Cognitive Dissonance
Sponsor:   Universidad Autonoma de Baja California
Active, not recruiting

Mon, 02 Nov 2020 12:00:00 EST

Evaluation of Iron Bioavailability From Iron Chlorophyllin

Condition:   Iron Deficiency
Interventions:   Dietary Supplement: SIC;   Dietary Supplement: SIC + AA combined;   Dietary Supplement: FeSO4;   Dietary Supplement: FeSO4 + AA combined;   Other: EP + FeSO4 combined;   Other: EP + FeSO4 + AA combined
Sponsor:   Swiss Federal Institute of Technology
Completed

Mon, 26 Oct 2020 12:00:00 EDT

Treatment of Covid-19 Infections Using Vitality Therapy or the Bible Cure

Condition:   Covid-19 Infections
Intervention:   Other: Infrared Energy and Dietary Supplement
Sponsor:   GAAD Medical Research Institute Inc.
Withdrawn

Wed, 14 Oct 2020 12:00:00 EDT

Effects of a Beverage Rich in Fruit Extracts on Risk Factors Associated With Cardiovascular Disease

Condition:   Cardiovascular Disease
Interventions:   Dietary Supplement: High polyphenol beverage;   Dietary Supplement: Placebo Beverage
Sponsor:   University of Glasgow
Unknown status

Fri, 21 Nov 2008 12:00:00 EST

In Utero Capacity Formation and Socio-economic Outcomes

Condition:   Folic Acid Deficiency
Intervention:   Other: observational follow-up
Sponsor:   Harvard University
Completed

Tue, 09 Aug 2011 12:00:00 EDT

Study to Assess Efficacy of Artemether-lumefantrine Prophylaxis Against Forest Malaria in Cambodia (PAL_Cambodia)

Condition:   Malaria
Interventions:   Drug: Artemether-lumefantrine;   Dietary Supplement: Multivitamin
Sponsors:   University of Oxford;   Global Fund
Recruiting

Thu, 01 Aug 2019 12:00:00 EDT

A Prospective, Randomized, Controlled, Multi-Center, Study Evaluating AutoloGel Therapy for Complete Closure of Wagner Grade 1-4 Diabetic Foot Ulcers, Venous Leg Ulcers and Stage II-IV Pressure Ulcers

Condition:   Impaired Wound Healing
Interventions:   Device: AutoloGel;   Other: Usual and Customary Care (UCC)
Sponsor:   Cytomedix
Withdrawn

Thu, 25 Sep 2014 12:00:00 EDT

Effect of Blueberries on Vascular Function in Healthy Men

Condition:   Healthy
Intervention:   Dietary Supplement: Blueberries
Sponsors:   University of Reading;   Alpro Foundation;   Wild Blueberry Association of North America
Completed

Thu, 10 Feb 2011 12:00:00 EST

Dietary Nitrate Supplements and Ischemic Stroke Recovery

Conditions:   Stroke;   Ischemic Stroke;   Cerebrovascular Accident
Interventions:   Drug: Beet it Beetroot juice;   Drug: Beet It Placebo Beetroot juice
Sponsor:   Wake Forest University Health Sciences
Completed

Wed, 20 Jul 2016 12:00:00 EDT

: Vascular Function in Health and Disease

Conditions:   Chronic Obstructive Pulmonary Disease;   Pulmonary Artery Hypertension;   Heart Failure;   Hypertension
Interventions:   Other: Maximum Exercise Tests;   Drug: BH4, L-NMMA, Vitamin C, Vitamin E, α-Lipoic Acid and L-Ascorbate;   Drug: BQ-123;   Drug: Fexofenadine, Ranitidine;   Other: Angiotensin-II, Valsartan;   Drug: Acetylcholine, Sodium Nitroprusside, Angiotensin-II, Norepinephrine, Phentolamine;   Drug: BQ-123, MitoQ, BH4
Sponsor:   Russell Richardson
Recruiting

Thu, 17 Nov 2016 12:00:00 EST

Effects of Nutraperf Consumption in Runners

Condition:   Nutrition Processes
Intervention:   Dietary Supplement: Carbohydrate drink
Sponsors:   Lescuyer Laboratory;   Centre Hospitalier Universitaire de Saint Etienne;   Université Savoie Mont Blanc
Completed

Mon, 01 Dec 2008 12:00:00 EST

Safety and Efficacy of Ivermectin and Doxycycline in Treatment of Covid-19

Condition:   Covid19
Interventions:   Drug: Ivermectin and Doxycycline;   Other: Placebo
Sponsor:   Bangladesh Medical Research Council (BMRC)
Not yet recruiting

Wed, 16 Sep 2020 12:00:00 EDT

Effect of Iron Versus Multiple Micronutrient Supplementation on Anemia in Preschool Children of Malaria-Endemic Area

Conditions:   Anemia;   Undernutrition
Intervention:   Dietary Supplement: micronutrient supplementation
Sponsors:   Centre National de la Recherche Scientifique et Technologique;   Universite Libre de Bruxelles, Belgium;   Fonds pour la recherche scientifique médicale (FRSM), Belgium
Completed

Wed, 05 Mar 2008 12:00:00 EST

Emergency Department Probiotic Treatment of Pediatric Gastroenteritis

Condition:   Gastroenteritis
Interventions:   Drug: Placebo;   Drug: Lacidofil
Sponsors:   Dr. Stephen Freedman;   Canadian Institutes of Health Research (CIHR);   Alberta Children's Hospital;   The Hospital for Sick Children;   Children's Hospital of Eastern Ontario;   St. Justine's Hospital;   IWK Health Centre;   Institut Rosell Lallemand;   London Health Sciences Center, Children's Hospital
Completed

Tue, 14 May 2013 12:00:00 EDT

Probiotics in the Treatment of Iron Deficiency in Children With Restless Leg Syndrome

Conditions:   Iron Deficiency;   Restless Leg Syndrome
Interventions:   Dietary Supplement: Probiotics;   Dietary Supplement: Placebo
Sponsor:   Children's Hospitals and Clinics of Minnesota
Completed

Tue, 12 Jun 2012 12:00:00 EDT

Comparison of 1 Liter PEG With Ascorbate and Sodium Picosulfate / Magnesium Citrate for High Quality Colon Cleansing

Condition:   Colonic Diseases
Interventions:   Drug: Polyethylene glycol + ascorbate;   Drug: Sodium picosulfate + magnesium citrate
Sponsor:   Parc de Salut Mar
Recruiting

Thu, 22 Oct 2020 12:00:00 EDT

Efficacy of a Dietary Supplementation in Reducing Hospital Admissions for COVID-19. Randomized Clinical Trial

Condition:   Covid19
Interventions:   Dietary Supplement: Vitamin and trace elements;   Dietary Supplement: Placebo
Sponsors:   Fundació Institut Germans Trias i Pujol;   Germans Trias i Pujol Hospital
Not yet recruiting

Fri, 12 Feb 2021 12:00:00 EST

Vitamin Gum Pharmacokinetics

Condition:   Nutrient Pharmacokinetics
Interventions:   Dietary Supplement: Vitamingum Sport;   Dietary Supplement: Vitamingum Immunity;   Dietary Supplement: Placebo
Sponsors:   Penn State University;   Vitaball, Inc.
Completed

Wed, 26 Jul 2017 12:00:00 EDT

The Effectivity and Safety of Favipiravir Compared to Oseltamivir as Adjuvant Therapy for COVID-19

Condition:   Covid19
Interventions:   Drug: Favipiravir;   Drug: Oseltamivir 75mg
Sponsor:   Indonesia University
Recruiting

Tue, 22 Sep 2020 12:00:00 EDT

Women's Antioxidant and Folic Acid Cardiovascular Study (WAFACS)

Conditions:   Cardiovascular Diseases;   Coronary Arteriosclerosis;   Coronary Disease;   Heart Diseases;   Myocardial Infarction;   Myocardial Ischemia
Interventions:   Behavioral: dietary supplements;   Drug: vitamin C;   Drug: vitamin E;   Drug: beta-carotene;   Drug: folic acid/Vitamin B6/Vitamin B12
Sponsors:   Brigham and Women's Hospital;   National Heart, Lung, and Blood Institute (NHLBI)
Completed

Thu, 28 Oct 1999 12:00:00 EDT

Influence of Obesity on Endogenous Oxalate Synthesis

Condition:   Kidney Stone
Intervention:   Dietary Supplement: controlled diet
Sponsor:   University of Alabama at Birmingham
Recruiting

Fri, 12 Oct 2018 12:00:00 EDT

Hypofractionated Radiation Therapy in Treating Participants With Prostate Cancer High-Risk Features Following Radical Prostatectomy

Conditions:   Prostate Adenocarcinoma;   Stage IIB Prostate Cancer AJCC v8;   Stage III Prostate Cancer AJCC v8;   Stage IIIA Prostate Cancer AJCC v8;   Stage IIIB Prostate Cancer AJCC v8;   Stage IIIC Prostate Cancer AJCC v8
Interventions:   Drug: Androgen Suppression;   Radiation: Hypofractionated Radiation Therapy;   Other: Quality-of-Life Assessment;   Other: Questionnaire Administration
Sponsors:   Mayo Clinic;   National Cancer Institute (NCI)
Active, not recruiting

Wed, 27 Jun 2018 12:00:00 EDT

Effects and Safety of OPK-88004 Doses in Men With Signs and Symptoms of Benign Prostatic Hyperplasia (BPH)

Condition:   Benign Prostatic Hyperplasia
Interventions:   Drug: Group-1 (15mg, OPK-88004);   Drug: Group-2 (25 mg,OPK-88004);   Other: Placebo
Sponsor:   OPKO Health, Inc.
Terminated

Fri, 29 Sep 2017 12:00:00 EDT

Safety and Efficacy of Nitric Oxide Gel in Promoting Hair Growth in Male Human Subjects With Androgenetic Alopecia

Condition:   Alopecia Androgenica
Interventions:   Other: Nitric Oxide (NO) Gel;   Other: Placebo gel
Sponsor:   China Medical University Hospital
Unknown status

Thu, 05 May 2011 12:00:00 EDT

Clinical Trials of Adjuvant Androgen Deprivation in Localized Prostate Cancer

Condition:   Prostate Adenocarcinoma
Interventions:   Drug: Short term androgen deprivation;   Drug: Long term androgen deprivation;   Radiation: Short term androgen deprivation;   Radiation: Long term androgen deprivation
Sponsor:   Fundación de Investigación Biomédica - Hospital Universitario de La Princesa
Completed

Thu, 26 Jun 2014 12:00:00 EDT

Efficacy Study Evaluating Chemotherapy in Prostate Cancer

Condition:   Prostate Cancer
Interventions:   Drug: Cabazitaxel + Androgen deprivation therapy;   Drug: Androgen deprivation therapy
Sponsor:   Örebro University, Sweden
Unknown status

Fri, 08 Nov 2013 12:00:00 EST

Metabolic Biomarkers in Hashimoto's Thyroiditis and Psoriasis

Conditions:   Hashimoto Disease;   Psoriasis
Intervention:   Combination Product: Nutraceutical Combination Plan
Sponsor:   University of Crete
Recruiting

Tue, 05 Jan 2021 12:00:00 EST

Iron Absorption From a Micronutrient Powder Containing Galacto-oligosaccharides (GOS)

Condition:   Anemia, Iron-Deficiency
Interventions:   Dietary Supplement: Fortified maize porridge (MNP+iron);   Dietary Supplement: Fortified maize porridge (MNP+iron+GOS)
Sponsors:   Swiss Federal Institute of Technology;   Jomo Kenyatta University of Agriculture and Technology;   International Centre for Behavioural Studies;   Msambweni District Hospital
Completed

Thu, 28 Jan 2016 12:00:00 EST

Respiratory and Autonomic Plasticity Following Intermittent Hypoxia

Condition:   Sleep Apnea Syndromes
Intervention:   Drug: Antioxidant cocktail
Sponsor:   VA Office of Research and Development
Completed

Thu, 12 Mar 2009 12:00:00 EDT

Efficacy and Safety of Ivermectin for Treatment and Prophylaxis of COVID-19 Pandemic

Condition:   Covid19
Interventions:   Drug: Ivermectin;   Drug: Hydroxychloroquine;   Behavioral: personal protective Measures
Sponsor:   Benha University
Completed

Wed, 16 Dec 2020 12:00:00 EST

Screening Tests in Detecting Colorectal Cancer

Condition:   Colorectal Cancer
Intervention:   Other: sample testing
Sponsors:   Alliance for Clinical Trials in Oncology;   National Cancer Institute (NCI);   Mayo Clinic
Completed

Mon, 27 Jan 2003 12:00:00 EST

A Study to Evaluate the Palatability of a Nutritional Support Biscuit (Fitabisc)

Condition:   Colorectal Surgery
Intervention:   Dietary Supplement: Fitabisc
Sponsor:   York Teaching Hospitals NHS Foundation Trust
Terminated

Fri, 01 Mar 2019 12:00:00 EST

Effect of a Nss to Reduce Complications in Patients With Covid-19 and Comorbidities in Stage III

Conditions:   Covid19;   Diabetes Mellitus;   Hypertension;   Obesity
Interventions:   Dietary Supplement: Nutritional support system (NSS);   Other: Control
Sponsor:   Anahuac University
Not yet recruiting

Tue, 11 Aug 2020 12:00:00 EDT

The Effects of a Dietary Supplement on Exercise Performance in Healthy Older Adults"

Condition:   Excessive Physical Exercise, Unspecified
Interventions:   Dietary Supplement: Arginine antioxidant supplements;   Dietary Supplement: Placebo
Sponsor:   University of California, Los Angeles
Completed

Tue, 23 Feb 2010 12:00:00 EST

The Efficiency of CAMS (Chinese Academy of Medical Sciences)-2016 Trial for Pediatric Acute Myeloid Leukemia

Condition:   Acute Myeloid Leukemia
Intervention:   Drug: Dasatinib
Sponsor:   Institute of Hematology & Blood Diseases Hospital
Recruiting

Fri, 02 Jun 2017 12:00:00 EDT

Prucalopride for Postoperative Ileus in Patients Undergoing Gastrointestinal Surgery

Condition:   Postoperative Ileus
Interventions:   Drug: Prucalopride;   Drug: Placebo
Sponsor:   Jinling Hospital, China
Completed

Mon, 09 Dec 2013 12:00:00 EST

A Randomized Multi-Intervention Trial to Inhibit Precancerous Gastric Lesions in Lingu, Shandong Province

Condition:   Precancerous Gastric Lesions
Intervention:   Drug: Amoxicillin/omeprazole
Sponsor:   National Cancer Institute (NCI)
Completed

Wed, 21 Jun 2006 12:00:00 EDT

Omega-3 PUFA in Prevention of Cardiovascular and Metabolic Diseases (CARDMET3)

Conditions:   Obesity, Abdominal;   Metabolic Syndrome;   Cardiovascular Risk Factor
Interventions:   Dietary Supplement: Chia seeds supplementation (25 g);   Dietary Supplement: Chia seeds supplementation (15 g);   Dietary Supplement: Combine supplementation: chia seeds (15g) and fish oil Maxi Cor 70+20;   Dietary Supplement: Fish oil supplementation
Sponsor:   Pavol Jozef Safarik University
Recruiting

Mon, 23 Dec 2019 12:00:00 EST

Baby Iron Bioavailability Study

Condition:   Iron Bioavailability
Interventions:   Other: Labeled iron salt Fe54;   Other: Labeled iron salt Fe57;   Other: Labeled iron salt Fe58
Sponsors:   Nestlé;   Swiss Federal Institute of Technology;   University of Malawi College of Medicine
Completed

Tue, 27 Nov 2018 12:00:00 EST

Efficacy of Melanostop Peeling for Improvement of Melasma

Condition:   Melasma
Intervention:   Other: Melanostop peel
Sponsor:   Higher School of Applied Sciences (VIST)
Unknown status

Fri, 01 Feb 2019 12:00:00 EST

Iron Bioavailability From Cereal-based Foods

Condition:   Iron Bioavailability
Interventions:   Other: Control Porridge;   Other: Reference Porridge A;   Other: Test Porridge B;   Other: Test Porridge C;   Other: Test Porridge D
Sponsors:   Purdue University;   United States Agency for International Development (USAID)
Recruiting

Wed, 29 Sep 2021 12:00:00 EDT

Prostate Cancer Prevention Trial With Quercetin and Genistein

Condition:   Primary Prevention of Prostate Cancer
Interventions:   Dietary Supplement: Quercetin supplement;   Dietary Supplement: Genistein supplement;   Dietary Supplement: Placebo
Sponsors:   University of Hohenheim;   University Hospital Tuebingen;   Quercegen Pharmaceuticals
Unknown status

Fri, 24 Feb 2012 12:00:00 EST

Effects of Essential and Non-Essential Amino Acids on Post-Exercise Muscle Collagen Synthesis in Young Men

Conditions:   Skeletal Muscle;   Extracellular Matrix;   Amino Acids Metabolism;   Exercise;   Dietary Supplements
Interventions:   Dietary Supplement: Essential Amino Acid;   Dietary Supplement: Collagen Peptide;   Dietary Supplement: Maltodextrin Placebo
Sponsor:   University of British Columbia
Recruiting

Thu, 22 Oct 2020 12:00:00 EDT

Nutrition, Health and Quality of Life: Development of New Formulations of Traditional Products of the "Made in Italy" Diet Optimized for Consumers With an Age Over 50 Years (MIAO 50)

Condition:   Aging
Intervention:   Dietary Supplement: fortified milk
Sponsor:   University of Bologna
Completed

Mon, 06 Jan 2014 12:00:00 EST

Volar Internal Plate Fixation vs. Plaster in Extra- Articular Distal Radial Fractures

Condition:   Displaced Extra-articular Distal Radius Fractures
Interventions:   Procedure: open reduction and internal fixation;   Other: Closed reduction and plaster
Sponsors:   Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA);   Onze Lieve Vrouwe Gasthuis;   Diakonessenhuis, Utrecht;   Elkerliek Hospital;   Groene Hart Ziekenhuis;   Dijklander Ziekenhuis;   Reinier de Graaf Groep;   Maasstad Hospital;   BovenIJ Hospital;   Rijnland Hospital;   Flevoziekenhuis;   Radboud University;   Maxima Medical Center;   Zaans Medisch Centrum
Completed

Wed, 08 Jan 2014 12:00:00 EST

Double-Blinded Clinical Trial Using Apatone®B for Symptomatic Postoperative Total Joint Replacements

Conditions:   Edematous;   Synovitis;   Foreign Body Reaction;   Osteolysis
Interventions:   Drug: Placebo;   Drug: Apatone®B
Sponsors:   IC-MedTech Corporation;   Summa Health System;   Crystal Clinic Orthopaedic Center LLC
Completed

Mon, 10 Jan 2011 12:00:00 EST

Lao Zinc Study: Effects of Two Forms of Daily Preventive Zinc Versus Therapeutic Zinc Supplementation

Condition:   Diarrhea
Interventions:   Dietary Supplement: MNP;   Dietary Supplement: preventive zinc supplement;   Dietary Supplement: therapeutic zinc supplement;   Dietary Supplement: preventive placebo supplement;   Dietary Supplement: therapeutic placebo supplement;   Dietary Supplement: placebo powder
Sponsors:   University of California, Davis;   National Institute of Public Health, Lao PDR;   USDA, Western Human Nutrition Research Center;   University of British Columbia;   Khon Kaen University;   Micronutrient Initiative;   The Mathile Institute for the Advancement of Human Nutrition
Completed

Wed, 29 Apr 2015 12:00:00 EDT

Orthomolecular Therapy and Asthma in Children

Condition:   Asthma
Intervention:   Dietary Supplement: Orthomolecular Therapy or Placebo Comparator
Sponsors:   Canadian Institute of Natural and Integrative Medicine;   Alberta Children's Hospital;   Alberta Health Services;   Alberta Heritage Foundation for Medical Research;   SickKids Foundation;   Lotte & John Hecht Memorial Foundation
Unknown status

Tue, 06 May 2008 12:00:00 EDT

Nutrition, Diabetes and Pulmonary TB/HIV

Conditions:   Tuberculosis;   HIV;   Diabetes
Interventions:   Dietary Supplement: Multimicronutrients;   Dietary Supplement: Energy and proteins
Sponsors:   University of Copenhagen;   National Institute for Medical Research, Tanzania;   The Danish Medical Research Council;   Danish Council for Development Research
Completed

Wed, 05 Apr 2006 12:00:00 EDT

Micronutrients and Child Health Study

Condition:   Malaria
Interventions:   Dietary Supplement: Zinc;   Dietary Supplement: Vitamins and minerals other than zinc;   Dietary Supplement: Vitamins plus zinc and other minerals;   Dietary Supplement: Placebo
Sponsors:   Wageningen University;   Kilimanjaro Christian Medical Centre, Tanzania
Completed

Tue, 26 Feb 2008 12:00:00 EST

Enhanced Natural Killer Cell Activity and RBAC

Condition:   Family Member
Intervention:   Dietary Supplement: Rice Bran Arabinoxylan Compound (RBAC)
Sponsor:   University of Miami
Completed

Tue, 24 Dec 2013 12:00:00 EST

Trial of Captafer® vs. Oral Iron Sulfate in the Treatment of Iron Deficiency Anemia in Patients With IBD

Conditions:   Iron Deficiency Anemia;   Inflammatory Bowel Disease
Interventions:   Drug: Captafer®;   Drug: Iron Sulfate
Sponsor:   American University of Beirut Medical Center
Unknown status

Tue, 17 May 2016 12:00:00 EDT

Low Dose Euthyrox in Treatments of Paraquat Intoxication.

Condition:   Paraquat Poisoning
Interventions:   Drug: Levothyroxine Sodium;   Drug: Traditional therapy
Sponsors:   Second Affiliated Hospital, School of Medicine, Zhejiang University;   First People's Hospital of Hangzhou;   Zhejiang Provincial Hospital of TCM
Not yet recruiting

Mon, 21 Oct 2019 12:00:00 EDT

Efficacy of Multiple Micronutrient Fortified Biscuits and Deworming in Vietnamese School Children

Condition:   Healthy
Intervention:   Dietary Supplement: worm treatment and multiple micronutrient fortified biscuits
Sponsor:   Neys-van Hoogstraten Foundation, The Netherlands
Completed

Tue, 05 Aug 2008 12:00:00 EDT

Can Lifestyle Changes Reverse Early-Stage Alzheimer's Disease

Condition:   Alzheimer Disease
Intervention:   Behavioral: Lifestyle medicine
Sponsors:   Preventive Medicine Research Institute;   University of California, San Francisco;   Harvard Medical School;   University of California, San Diego
Recruiting

Wed, 28 Oct 2020 12:00:00 EDT

Diabetic Retinopathy Functional Evaluation Study: Monitoring Carotenoid Vitamins Treatment Using ERG

Conditions:   Diabetes;   Diabetic Retinopathy
Intervention:   Dietary Supplement: DVS supplementation
Sponsors:   ZeaVision, LLC;   Northeastern State University;   Western University of Health Sciences;   Diopsys, Inc.
Recruiting

Mon, 07 Oct 2019 12:00:00 EDT

Investigating the Effects of Daily Consumption of Blueberry (Poly)Phenols on Vascular Function and Cognitive Performance

Conditions:   Healthy Aging;   Healthy
Interventions:   Dietary Supplement: Wild Blueberry powder;   Dietary Supplement: Placebo
Sponsors:   King's College London;   University of Reading
Completed

Tue, 10 Sep 2019 12:00:00 EDT

Low-dose Iron Supplementation and Markers of Iron Status Among Non-anemic, Iron-deficient Women

Condition:   Non-anemic Iron Deficiency
Intervention:   Dietary Supplement: Blood Builder®/Iron Response®
Sponsor:   University of Maryland, Baltimore
Completed

Wed, 17 Feb 2016 12:00:00 EST

Iron and Prebiotics Fortification in Kenyan Infants

Conditions:   Anemia;   Iron Deficiency;   Diarrhea;   Malaria;   Respiratory Tract Infections (RTI);   Antibiotics;   Gut Inflammation;   Prebiotics;   Vaccine Response
Intervention:   Dietary Supplement: Fortified maize porridge
Sponsors:   Swiss Federal Institute of Technology;   DSM Nutritional Products, Inc.
Completed

Mon, 21 Apr 2014 12:00:00 EDT

Effectiveness of Selling Micronutrient Sprinkles in Rural Kenya

Condition:   Anemia, Iron-deficiency
Intervention:   Dietary Supplement: Micronutrient powders (Sprinkles)
Sponsors:   Centers for Disease Control and Prevention;   Safe Water and AIDS Project;   Kenya Medical Research Institute;   Global Alliance for Improved Nutrition
Completed

Thu, 18 Mar 2010 12:00:00 EDT

Zinc Versus Multivitamin Micronutrient Supplementation in the Setting of COVID-19

Conditions:   Healthy;   Health Care Worker Patient Transmission;   Aging
Interventions:   Dietary Supplement: PreserVision AREDS formulation soft gels or tablets;   Dietary Supplement: Multivitamin with 11mg of zinc
Sponsor:   Mayo Clinic
Completed

Wed, 16 Sep 2020 12:00:00 EDT

Evaluation of Additional Treatments for COVID-19: a Randomized Trial in Niger

Condition:   Covid-19
Interventions:   Drug: Lopinavir-Ritonavir Drug Combination;   Combination Product: Standard Care
Sponsors:   Epicentre;   Université Abdou Moumouni;   Centre de Recherche Médicale et Sanitaire;   Ministry of Public Health, Republic of Niger
Withdrawn

Mon, 01 Jun 2020 12:00:00 EDT

The Efficacy of Tendoactive, Eccentric Training, and the Combination of Both as a Treatment of Achilles Tendinopathy

Condition:   Achilles Tendinopathy
Interventions:   Drug: Tendoactive;   Behavioral: Eccentric training
Sponsor:   Bioiberica
Completed

Tue, 25 Sep 2012 12:00:00 EDT

Prospective Double-Blind Randomized Controlled Clinical Trial in the Gingivitis Prevention With OPCs

Condition:   Gingivitis
Interventions:   Dietary Supplement: Oligomeric Proanthocyanidins;   Dietary Supplement: Placebo
Sponsor:   University of Seville
Completed

Wed, 05 Aug 2015 12:00:00 EDT

Evaluation of the Effect of FertyBiotic Pregnancy in the Metabolic Profile in Pregnant Women

Condition:   Pregnancy Related
Interventions:   Dietary Supplement: FertyBiotic Pregnancy;   Other: Control
Sponsor:   Fertypharm
Recruiting

Wed, 23 Jun 2021 12:00:00 EDT

Effect of a Nutritional Support System for Improving Gross Motor Function in Cerebral Palsy

Conditions:   Nutrition Disorder, Child;   Gross Motor Development Delay;   Neuro: Cerebral Palsy;   Diet Modification;   Probiotics
Interventions:   Dietary Supplement: Nutritional Support System (NSS);   Other: deworming;   Other: recommended diet
Sponsor:   Anahuac University
Completed

Wed, 01 May 2019 12:00:00 EDT

Integrative Medicine Approach to the Management of Asthma in Adults

Condition:   Asthma
Intervention:   Behavioral: Integrative Medicine
Sponsor:   Beth Israel Medical Center
Completed

Fri, 13 Feb 2009 12:00:00 EST

Nutritional Supplementation for Recurrent Urinary Tract Infections in Women

Condition:   Recurrent Urinary Tract Infection
Interventions:   Dietary Supplement: WelTract;   Dietary Supplement: Placebo
Sponsors:   AmPurity Nutraceuticals, LLC;   Arkansas Urology
Not yet recruiting

Tue, 24 Jul 2018 12:00:00 EDT

The Efficacy of Early Postoperative Enteral Immunonutrition in Low-Risk Cardiac Surgery Patients

Condition:   Cardiac Surgery
Interventions:   Dietary Supplement: Immunonutrients + normal daily meal;   Dietary Supplement: Normal daily meal
Sponsor:   Vilnius University
Unknown status

Tue, 06 Aug 2019 12:00:00 EDT

Accute Effect of B-Turmactive Both on Mild and Moderate Knee Pain on Healthy Volunteers

Conditions:   Knee Injuries;   Inflammation Knees
Interventions:   Dietary Supplement: B-turmactive;   Dietary Supplement: Placebo
Sponsors:   Technological Centre of Nutrition and Health, Spain;   Hospital Universitari Sant Joan de Reus;   University Rovira i Virgili
Unknown status

Thu, 29 Jun 2017 12:00:00 EDT

Mitochondrial Cocktail for Gulf War Illness

Conditions:   Gulf War Syndrome;   Persian Gulf Syndrome;   Mitochondrial Disorders
Interventions:   Dietary Supplement: Individualized mitochondrial cocktail;   Dietary Supplement: Placebo
Sponsor:   University of California, San Diego
Enrolling by invitation

Fri, 17 Jun 2016 12:00:00 EDT

Evaluation of Jarro-Dophilus EPS® Probiotic Formulations

Condition:   Healthy
Interventions:   Dietary Supplement: Jarro-Dophilus EPS® (5 billion CFU/capsule);   Dietary Supplement: Jarro-Dophilus EPS® High Potency (25 billion CFU/capsule);   Dietary Supplement: Placebo
Sponsors:   University of Florida;   Lallemand Health Solutions
Completed

Fri, 26 Feb 2016 12:00:00 EST

Impact of isoQUercetin and Aspirin on Platelet Function

Condition:   Cardiovascular Disease
Interventions:   Drug: Vehicle control;   Drug: Isoquercetin;   Drug: Aspirin;   Drug: Isoquercetin plus Aspirin
Sponsors:   University of Reading;   Biotechnology and Biological Sciences Research Council;   Quercegen Pharmaceuticals
Withdrawn

Mon, 15 Aug 2016 12:00:00 EDT

Orange Juice Consumption and Cognitive Function

Condition:   Nerve Degeneration
Interventions:   Dietary Supplement: High flavanone orange juice;   Dietary Supplement: Control orange juice
Sponsor:   University of Reading
Completed

Thu, 10 Mar 2011 12:00:00 EST

Antioxidants for Prevention of Cataracts Follow-up Study

Condition:   Cataract
Interventions:   Dietary Supplement: Antioxidant;   Dietary Supplement: Placebo
Sponsors:   University of California, San Francisco;   Aravind Eye Hospitals, India
Completed

Tue, 14 Aug 2012 12:00:00 EDT

Investigating the Wrinkle Reduction Potential of a Novel Compounded Skin Care Cream

Condition:   Skin Care
Interventions:   Combination Product: Skin Care Cream;   Drug: Placebo
Sponsor:   Wayne State University
Recruiting

Mon, 18 Mar 2019 12:00:00 EDT

Age-Related Eye Disease Study (AREDS)

Conditions:   Macular Degeneration;   Cataract;   Lens Opacities
Interventions:   Dietary Supplement: Antioxidants;   Dietary Supplement: Zinc;   Dietary Supplement: Antioxidants and zinc
Sponsors:   National Eye Institute (NEI);   Bausch & Lomb Incorporated
Completed

Fri, 24 Sep 1999 12:00:00 EDT

A Study Investigating the Effect of Digesta-Lac in Healthy Adults With Occasional Constipation

Condition:   Occasional Constipation
Interventions:   Dietary Supplement: Digesta Lac;   Other: Placebo
Sponsors:   KGK Science Inc.;   Global Institute of Probiotics
Completed

Wed, 22 Apr 2015 12:00:00 EDT

Efficacy of Focused Shock Waves Combined With Adjuvant Therapy With Tendon Supplement

Condition:   Fasciitis, Plantar
Interventions:   Dietary Supplement: Tendisulfur Pro;   Device: Focused shock wave
Sponsor:   Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari
Completed

Fri, 11 Dec 2020 12:00:00 EST

Acute and Chronic Effects of 100% Florida Orange Juice Consumption on Cognitive Performance in 7-10 Year Old Children

Condition:   Healthy
Interventions:   Dietary Supplement: 100% Florida OJ;   Dietary Supplement: Placebo Equicaloric Orange Drink
Sponsors:   University of Leeds;   Department of Citrus, State of Florida USA;   University of East Anglia
Completed

Fri, 01 Apr 2016 12:00:00 EDT

Role of Antioxidants Supplementation in Chronic Pancreatitis

Condition:   Chronic Pancreatitis
Interventions:   Dietary Supplement: Antioxidants;   Dietary Supplement: Placebo
Sponsor:   All India Institute of Medical Sciences, New Delhi
Completed

Thu, 27 Apr 2006 12:00:00 EDT

The Effects of Standard Protocol With or Without Colchicine in Covid-19 Infection

Condition:   COVID-19
Intervention:   Drug: Colchicine Tablets
Sponsor:   Shahid Beheshti University of Medical Sciences
Recruiting

Fri, 24 Apr 2020 12:00:00 EDT

Relative Bioavailability Study in Healthy Subjects

Condition:   Infections, Bacterial
Intervention:   Drug: GSK1322322
Sponsor:   GlaxoSmithKline
Completed

Fri, 19 Jun 2009 12:00:00 EDT

Is a Carnitine Based Food Supplement (PorimoreTM) for Infertile Men Superior to Folate and Zinc With Regard to Pregnancy Rates in Intrauterine Insemination Cycles?

Condition:   Male Infertility
Interventions:   Dietary Supplement: Porimore - A Carnitine based food supplement;   Dietary Supplement: Zinc and Folate Supplementation
Sponsor:   Shaare Zedek Medical Center
Unknown status

Thu, 25 Feb 2010 12:00:00 EST

Diabetes Visual Function Supplement Study

Conditions:   Diabetes Mellitus - Type 1;   Diabetes Mellitus - Type 2;   Non-proliferative Diabetic Retinopathy
Interventions:   Dietary Supplement: multi-component nutritional supplement capsules;   Dietary Supplement: multi-component dietary supplement
Sponsor:   ZeaVision, LLC
Completed

Fri, 20 Jul 2012 12:00:00 EDT

Effects of Antioxidants and B Vitamins Supplements on Inflammation in Obese Diabetic Patients

Conditions:   Diabetes;   Obesity
Interventions:   Dietary Supplement: vitamins;   Drug: Placebo
Sponsors:   United Arab Emirates University;   Tawam Hospital
Completed

Mon, 24 Sep 2012 12:00:00 EDT

Body Mass Index and Age Correlate With Antioxidant Supplementation Effects on Sperm Quality

Condition:   Male Infertility
Interventions:   Dietary Supplement: Proxeed;   Other: Placebo
Sponsor:   University of Roma La Sapienza
Completed

Tue, 26 Nov 2019 12:00:00 EST

Study Designed to Evaluate the Effect of CimetrA in Patients Diagnosed With COVID-19

Conditions:   Covid19;   Corona Virus Infection
Interventions:   Diagnostic Test: Biochemistry blood test;   Diagnostic Test: Hematology blood test;   Diagnostic Test: D-Dimer test (coagulation);   Diagnostic Test: Inflammatory markers;   Diagnostic Test: Vital signs;   Diagnostic Test: VAS scale;   Diagnostic Test: WHO Ordinal Score;   Diagnostic Test: COVID-19-Related Symptoms assessment;   Diagnostic Test: COVID-19-Impact on Quality-of-Life Questionnaire;   Diagnostic Test: POST- COVID-19 Functional Status Scale:;   Diagnostic Test: Pregnancy test;   Diagnostic Test: Physical examination;   Diagnostic Test: PK parameters;   Diagnostic Test: SARS-CoV-2 test (PCR);   Diagnostic Test: ECG;   Drug: Treatment administration (twice a day)
Sponsor:   MGC Pharmaceuticals d.o.o
Not yet recruiting

Wed, 08 Sep 2021 12:00:00 EDT

Clinical Study Designed to Evaluate the Effect of CimetrA in Patients Diagnosed With COVID-19

Conditions:   Corona Virus Infection;   Covid19;   SARS-CoV Infection
Interventions:   Drug: Placebo administration;   Diagnostic Test: Confirm SARS-CoV-2 infection;   Procedure: Physical Examination;   Procedure: Vital Signs;   Diagnostic Test: Hematology blood test;   Diagnostic Test: Biochemistry blood test;   Other: NEWS score;   Diagnostic Test: PK test;   Diagnostic Test: blood test for inflammatory markers;   Diagnostic Test: D-dimer test;   Other: VAS scale;   Diagnostic Test: Urine pregnancy test for women of childbearing potential;   Procedure: ECG;   Other: COVID-19-Impact on Quality of Life Questionnaire;   Drug: CimetrA-1;   Drug: CimetrA-2
Sponsor:   MGC Pharmaceuticals d.o.o
Recruiting

Wed, 17 Mar 2021 12:00:00 EDT

Ivermectin Versus Standard Treatment in Mild COVID-19

Condition:   Covid19
Intervention:   Drug: Ivermectin Tablets
Sponsor:   Assiut University
Not yet recruiting

Thu, 24 Jun 2021 12:00:00 EDT

Assessment of a Pre-Workout Dietary Supplement

Condition:   Dietary Modification
Interventions:   Dietary Supplement: C4 Extreme;   Dietary Supplement: C4 Extreme (without Advantra Z;   Dietary Supplement: Placebo
Sponsors:   Texas A&M University;   Nutrabolt
Completed

Wed, 02 Nov 2016 12:00:00 EDT

Efficacy and Safety of Silicone Cream Containing Allium Cepa Extract

Condition:   Cicatrix
Interventions:   Device: silicone cream containing Allium Cepa extract;   Device: Commercial scar gel
Sponsor:   Chulalongkorn University
Not yet recruiting

Sat, 18 Jan 2020 12:00:00 EST

Trial of GM-CSF Given in Combination With Ketoconazole and Mitoxantrone in Patients With Progressive Prostate Cancer

Condition:   Prostatic Neoplasms
Interventions:   Drug: GM-CSF;   Drug: Ketoconazole;   Drug: Mitoxantrone
Sponsors:   The Methodist Hospital Research Institute;   Bayer
Terminated

Wed, 14 Mar 2007 12:00:00 EDT

Drusen Morphology Changes in Nonexudative Age-related Degeneration After Oral Antioxidants Supplementation

Condition:   Macular Degeneration
Intervention:   Dietary Supplement: Antioxidant
Sponsor:   Germans Trias i Pujol Hospital
Completed

Wed, 15 Oct 2014 12:00:00 EDT

Prevention of Intrauterine Growth Retardation in Hounde District, Burkina Faso

Condition:   Multiple Micronutrient Deficiencies During Pregnancy
Interventions:   Dietary Supplement: Multiple micronutrient supplements (MMN);   Dietary Supplement: IFA
Sponsors:   Institute of Tropical Medicine, Belgium;   Nutrition Tiers Monde, Belgique;   Centre Muraz
Completed

Tue, 25 Mar 2008 12:00:00 EDT

Effects of a Pre-Workout Dietary Supplement on Training Adaptations

Condition:   Dietary Modification
Intervention:   Dietary Supplement: C4 Extreme, C4 Extreme (without Advantra Z)
Sponsors:   Texas A&M University;   Nutrabolt
Completed

Wed, 21 Dec 2016 12:00:00 EST

Trigona Honey and Intestinal Microbiota Among Obese People

Condition:   Obesity
Interventions:   Dietary Supplement: Trigona honey;   Dietary Supplement: control
Sponsor:   Hasanuddin University
Recruiting

Fri, 23 Jul 2021 12:00:00 EDT

A Trial of Vitamins and HAART in HIV Disease Progression

Condition:   HIV Infections
Interventions:   Dietary Supplement: Multivitamins (including B, C and E);   Dietary Supplement: Multivitamins B, C and E
Sponsors:   Harvard School of Public Health;   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Completed

Tue, 03 Oct 2006 12:00:00 EDT

Comparison of the Effect of Two Treatments on the Nutritional and Micronutrient Status of Malnourished Children

Condition:   Malnutrition
Interventions:   Dietary Supplement: Beverage fortified with 21 vitamins and minerals;   Dietary Supplement: Lactose-free milk
Sponsor:   Association for the Study and Prevention of HIV/AIDS
Unknown status

Wed, 18 Jul 2012 12:00:00 EDT

Feasibility and Effectiveness of Distributing Micronutrient Sprinkles to Reduce Prevalence of Anemia

Condition:   Anemia
Interventions:   Dietary Supplement: "Sprinkles" containing mulitple micronutrients;   Behavioral: Education/communication on use of micronutrient sprinkles;   Dietary Supplement: Fortified food aid (corn-soy blend)
Sponsors:   International Food Policy Research Institute;   Cornell University;   World Vision;   Micronutrient Initiative
Completed

Wed, 21 Sep 2005 12:00:00 EDT

Impact of Maternal Pomegranate Juice on Brain Injury in Infants With Intrauterine Growth Restriction (IUGR)

Condition:   Intrauterine Growth Restriction
Interventions:   Dietary Supplement: Pomegranate Juice;   Dietary Supplement: Placebo
Sponsors:   Washington University School of Medicine;   POM Wonderful LLC;   University of California, Los Angeles
Completed

Tue, 11 Nov 2008 12:00:00 EST

Evaluation of the Efficacy of a Food Supplement in Reducing Hair Loss in Male Subjects

Condition:   Hair Loss
Interventions:   Dietary Supplement: Alline proMEN;   Dietary Supplement: Placebo
Sponsors:   Laboratoires Pharmaceutiques Trenker;   Complife Italia S.r.l;   Università degli Studi di Pavia
Completed

Thu, 13 May 2021 12:00:00 EDT

Impact of Pre-pregnancy Micronutrient Supplementation on Maternal and Child Outcomes

Conditions:   Anemia;   Intrauterine Growth Retardation;   Preterm Delivery;   Iron Deficiency
Interventions:   Dietary Supplement: Multiple Micronutrient;   Dietary Supplement: Iron and Folic Acid;   Dietary Supplement: Folic Acid
Sponsors:   Emory University;   Micronutrient Initiative;   The Mathile Institute for the Advancement of Human Nutrition
Completed

Wed, 15 Aug 2012 12:00:00 EDT

Effects of Dietary Supplements on Response to Air Pollution

Condition:   Inflammation
Interventions:   Dietary Supplement: Placebo;   Dietary Supplement: Antioxidant, anti-inflammatory dietary supplement
Sponsors:   Utah State University;   USANA Health Sciences
Completed

Thu, 08 Dec 2011 12:00:00 EST

Anti-inflammatory/Antioxidant Oral Nutrition Supplementation in COVID-19

Condition:   COVID-19
Interventions:   Dietary Supplement: Oral supplement enriched in antioxidants;   Dietary Supplement: cellulose-containing placebo capsules
Sponsor:   King Saud University
Recruiting

Thu, 26 Mar 2020 12:00:00 EDT

Encapsulated Juice Powder Concentrate for Preventing Common Cold Symptoms

Condition:   Common Cold
Interventions:   Dietary Supplement: Juice Plus;   Dietary Supplement: Placebo
Sponsors:   Charite University, Berlin, Germany;   NSA, Collierville, TN, USA
Completed

Thu, 23 Oct 2008 12:00:00 EDT

Probiotics in Pediatric Chronic Cholestasis

Condition:   Cholestatic Liver Disease
Interventions:   Other: placebo;   Combination Product: probiotics
Sponsor:   Indonesia University
Recruiting

Mon, 08 Mar 2021 12:00:00 EST

Acute Study on Muscle Soreness, Damage, and Performance

Conditions:   Soreness, Muscle;   Performance Enhancing Product Use;   Damage Muscle
Interventions:   Dietary Supplement: Pre-workout plus and protein recovery plus;   Other: Placebo
Sponsors:   Pharmanex;   University of North Carolina, Chapel Hill
Completed

Sat, 18 Jan 2020 12:00:00 EST

Low Antioxidant Diet in Controlling Cachexia in Patients With Oropharyngeal Cancer Receiving Chemotherapy and Radiation Therapy

Conditions:   Cachexia;   Head and Neck Cancer;   Weight Changes
Interventions:   Other: ADD;   Other: Placebo
Sponsors:   UNC Lineberger Comprehensive Cancer Center;   National Cancer Institute (NCI)
Completed

Thu, 14 Jun 2007 12:00:00 EDT

The Use of an Oral Mixture of Arginine, Glutamine and Beta-hydroxy-beta-methylbutyrate for Treatment of Pressure Ulcers

Conditions:   Pressure Ulcers Stage III;   Pressure Ulcer, Stage IV
Intervention:   Dietary Supplement: ABOUND
Sponsors:   Our Lady of Maryknoll Hospital;   Wong Tai Sin Hospital
Unknown status

Tue, 31 Jan 2017 12:00:00 EST

Fatigue Reduction Diet

Condition:   Chronic Fatigue
Intervention:   Behavioral: Social Cognitive Theory
Sponsors:   University of Michigan;   University of Michigan Rogel Cancer Center
Completed

Thu, 18 Jul 2013 12:00:00 EDT

Acceptability and Feasibility of Micronutrient Powders Versus Iron Syrup for Anemia Prevention in Young Children

Condition:   Anemia
Interventions:   Dietary Supplement: Iron and Folic Acid (IFA);   Dietary Supplement: Micronutrient Powders (MNP);   Behavioral: Iron Plus Strategy Counseling
Sponsors:   Emory University;   International Food Policy Research Institute
Completed

Fri, 20 Nov 2015 12:00:00 EST

Effect of Omega-3-fatty Acids on Blood Levels Omega-3 Fatty Acids in Patients With Age-related Macular Degeneration

Condition:   Macular Degeneration
Intervention:   Dietary Supplement: Omega-3 fatty acid
Sponsors:   Wills Eye;   Physician Recommended Nutriceuticals
Completed

Mon, 30 Jul 2012 12:00:00 EDT

Efficacy of Supplementation With Probiotics as Adjuvant to Mechanical Treatment in Chronic Periodontitis

Condition:   Probiotics, Periodontitis
Interventions:   Device: Ultrasonic periodontal Debridement, with appropriate device;   Biological: Analyzes of periodontopathogenic bacteria;   Genetic: IL1B test;   Biological: Salivary Sampling;   Device: Halitosis measure
Sponsor:   PiLeJe
Completed

Wed, 13 Jun 2018 12:00:00 EDT

Potentiation of Chemotherapy in Brain Tumors by Zinc

Condition:   Newly Diagnosed Glioblastoma Who Underwent at Least Partial Resection of the Tumor Surgically
Intervention:   Dietary Supplement: zinc and ascorbate
Sponsor:   Sheba Medical Center
Recruiting

Tue, 28 Jul 2020 12:00:00 EDT

Antenatal Micronutrient Supplementation and Infant Survival

Conditions:   Infant Mortality;   Preterm Birth;   Low Birth Weight;   Neonatal Mortality;   Perinatal Mortality
Interventions:   Dietary Supplement: Iron (27 mg) - folic acid (600 ug);   Dietary Supplement: Multiple micronutrient
Sponsors:   Johns Hopkins Bloomberg School of Public Health;   Bill and Melinda Gates Foundation;   United States Agency for International Development (USAID);   Mahidol University;   Johns Hopkins University;   Beximco Pharmaceuticals Ltd.;   DSM Nutritional Products, Inc.
Completed

Thu, 12 Mar 2009 12:00:00 EDT

Effect of Micronutrients and Life Skills Education on the Health and Nutrition of Adolescent and Young Women in Pakistan

Conditions:   Adolescents;   Anemia;   Pregnancy;   Empowerment
Interventions:   Dietary Supplement: Multiple micronutrients (UNIMMAP composition);   Behavioral: Life skills based education
Sponsors:   Aga Khan University;   The Hospital for Sick Children;   National Program for Family Planning and Primary Health Care;   Bill and Melinda Gates Foundation
Active, not recruiting

Tue, 19 Sep 2017 12:00:00 EDT

Effect of a Nootropic on the Cognitive Performance in Young Adults

Condition:   Cognitive Change
Interventions:   Dietary Supplement: Nootropic;   Dietary Supplement: Placebo
Sponsor:   Universidad de Granada
Not yet recruiting

Wed, 10 Mar 2021 12:00:00 EST

Cervical Preparation Before Dilation and Evacuation

Condition:   Abortion, Induced
Interventions:   Other: Mifepristone;   Drug: misoprostol;   Device: Osmotic dilators;   Other: placebo
Sponsors:   Planned Parenthood League of Massachusetts;   Society of Family Planning
Completed

Mon, 17 Dec 2012 12:00:00 EST

Effectiveness of Ivermectin and Doxycycline on COVID-19 Patients

Condition:   Covid19
Interventions:   Drug: Ivermectin and Doxycyline;   Drug: Standard of care
Sponsor:   Alkarkh Health Directorate-Baghdad
Completed

Mon, 19 Oct 2020 12:00:00 EDT

A Study to Examine the Effect of a Thermogenic Energy Drink in Healthy Adults

Condition:   Metabolism
Interventions:   Dietary Supplement: Thermogenic Energy Drink - Active Study Product Formula;   Dietary Supplement: Placebo
Sponsors:   Rowdy Energy;   Biofortis Clinical Research, Inc.
Active, not recruiting

Thu, 30 Sep 2021 12:00:00 EDT

Project Grow Smart: Intervention Trial of Multiple Micronutrients and Early Learning Among Infants in India

Conditions:   Nutritional Deficiencies;   Developmental Delay
Interventions:   Dietary Supplement: MNP;   Behavioral: Early Learning
Sponsors:   University of Maryland, Baltimore;   Indian Council of Medical Research;   The Mathile Institute for the Advancement of Human Nutrition;   Micronutrient Initiative
Completed

Thu, 09 Aug 2012 12:00:00 EDT

The Effects of the Dietary Supplement CardioFlex Q10 on Reducing Cardiovascular Disease Risk Factors in Adults

Conditions:   Cardiovascular Diseases;   Cardiovascular Abnormalities;   Heart Attack;   Stroke;   Hypertension
Interventions:   Dietary Supplement: CardioFlex Q10;   Dietary Supplement: Placebo
Sponsor:   University of Manitoba
Completed

Fri, 01 Feb 2019 12:00:00 EST

Aloe Vera and Chlorhexidine Against Traumatic Oral Ulcers

Condition:   Oral Ulcer
Interventions:   Drug: Antiseptic clorhexidine gel (Lacer, Barcelona, Spain);   Drug: Master formula of aloe vera gel 80%
Sponsors:   University of Santiago de Compostela;   Alfonso X El Sabio University
Completed

Thu, 16 Aug 2018 12:00:00 EDT

Sumor as Adjuvant Therapy in Treatment-resistant Major Depression

Condition:   Major Depressive Disorder
Interventions:   Dietary Supplement: SUMOR;   Other: Placebo
Sponsor:   Azienda Ospedaliero-Universitaria Careggi
Not yet recruiting

Mon, 05 Apr 2021 12:00:00 EDT

Bioavailability of Vitamin D in Cod Liver Oil and Multivitamin Tablets in Healthy Subjects in Norway

Condition:   Healthy
Interventions:   Dietary Supplement: Fish oil capsule (specially manufactured for the study);   Dietary Supplement: Multivitamin tablet of type: Vitaplex ABCD
Sponsors:   University of Oslo;   Norwegian Institute of Public Health;   Hormone Laboratory, Aker University Hospital, Oslo, Norway;   Norwegian Foundation for Health and Rehabilitation
Completed

Wed, 30 Nov 2011 12:00:00 EST

Evaluation of a Fixed Combination of Herbal Extracts to Prevent Symptoms Alcohol-induced Hangovers

Conditions:   Headache;   Nausea;   Dizziness;   Sleepiness;   Anxiety;   Thirst
Interventions:   Dietary Supplement: LACIME Anti-hangover;   Other: Placebo
Sponsors:   Incara Lab;   Phytomed AB
Completed

Tue, 03 Dec 2019 12:00:00 EST

Trace Element Replenishment Study in Hemodialysis Patients

Condition:   End Stage Renal Disease
Interventions:   Dietary Supplement: Low dose: supplemental zinc, selenium and vitamin E;   Dietary Supplement: Standard renal vitamin: B and C renal vitamin;   Dietary Supplement: Medium dose: supplemental zinc, selenium and vitamin E
Sponsors:   Marcello Tonelli;   Alberta Health Services
Completed

Thu, 17 Nov 2011 12:00:00 EST

Viviscal Extra-Strength Formulation To Promote Hair Growth And Decrease Shedding In Women With Thinning Hair

Condition:   Hair Thinning
Interventions:   Dietary Supplement: Viviscal Extra-Strength Supplement;   Other: Placebo tablet
Sponsors:   Ablon Skin Institute Research Center;   Irish Response t/a Lifes2good
Completed

Fri, 21 Nov 2014 12:00:00 EST

Efficacy of the New Viviscal Professional Strength Oral Supplement in Females With Thinning Hair

Condition:   Hair Thinning
Interventions:   Dietary Supplement: New Viviscal Professional Supplement;   Dietary Supplement: Placebo tablets
Sponsors:   Ablon Skin Institute Research Center;   Irish Response t/a Lifes2good;   DeNova Research
Completed

Wed, 26 Nov 2014 12:00:00 EST

Monitoring and Evaluation of Micronutrients (Sprinkles) Project

Condition:   Anemia
Interventions:   Dietary Supplement: SPRINKLES;   Behavioral: Nutrition education
Sponsors:   Aga Khan University;   Micronutrient Initiative;   M/S SEBCON;   Pakistan Ministry of Health;   National Programme of Family Planning and Primary Health Care
Completed

Wed, 16 Apr 2008 12:00:00 EDT

Real-life Evaluation of the Effect of ADT in Prostate Cancer Patients in Asia (READT Asia Study)

Condition:   Prostate Cancer
Interventions:   Procedure: Androgen deprivation therapy - bilateral orchidectomy;   Drug: Androgen deprivation therapy - GnRH agonist;   Drug: Androgen deprivation therapy - GnRH antagonist
Sponsor:   Chinese University of Hong Kong
Recruiting

Fri, 12 Oct 2018 12:00:00 EDT

Obesity and Endogenous Oxalate Synthesis

Conditions:   Obesity;   Kidney Stone
Interventions:   Other: Normal Individuals;   Other: Calcium Oxalate Kidney Stone Formers;   Other: Type 2 Diabetes;   Other: Type 2 diabetic kidney stone formers
Sponsors:   University of Alabama at Birmingham;   National Institutes of Health (NIH);   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Recruiting

Thu, 17 Jan 2019 12:00:00 EST

Estrogen and Diabetes

Condition:   Diabetes Mellitus, Type 1
Interventions:   Dietary Supplement: Antioxidant Cocktail;   Dietary Supplement: Resveratrol;   Other: Placebo
Sponsors:   Augusta University;   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting

Mon, 19 Feb 2018 12:00:00 EST

Experimental fMRI Study of Guanfacine and Lisdexamfetamine in ADHD Adolescents

Condition:   ADHD
Interventions:   Drug: Lisdexamfetamine dimesylate;   Drug: Guanfacine Extended Release Oral Tablet;   Drug: Placebo
Sponsors:   King's College London;   Shire
Recruiting

Tue, 07 Nov 2017 12:00:00 EST

Effect of Neo40 on PAD

Condition:   Peripheral Artery Disease
Interventions:   Dietary Supplement: Neo40;   Dietary Supplement: Placebo
Sponsors:   HumanN;   The Methodist Hospital Research Institute
Unknown status

Mon, 17 Oct 2016 12:00:00 EDT

The Effects of a High Protein Diet on Microbiota, Gastrointestinal Function and Wellness in Older Women

Condition:   Aging
Interventions:   Dietary Supplement: Probiotic capsule and Fiber Sachet;   Dietary Supplement: Probiotic capsule and Placebo sachet;   Dietary Supplement: Placebo capsule and Fiber Sachet;   Dietary Supplement: Placebo capsule and Placebo sachet
Sponsors:   University of Florida;   Lallemand Health Solutions
Completed

Fri, 15 May 2015 12:00:00 EDT

Hormone Suppression and Radiation Therapy for 6 Months With/Without Docetaxel for High Risk Prostate Cancer

Condition:   Prostate Cancer
Interventions:   Drug: Docetaxel;   Drug: Androgen Hormonal Suppression and Radiation;   Drug: Androgen Suppression Therapy and Radiation Therapy
Sponsors:   Dana-Farber Cancer Institute;   Sanofi
Completed

Tue, 28 Jun 2005 12:00:00 EDT

Nutrition Interventions to Support the Immune System in Response to Stress

Condition:   Mitigation of Immune Function Decrements in Response to Stress
Interventions:   Dietary Supplement: Immune-enhancing nutritional beverage;   Dietary Supplement: Probiotics (BB-12);   Dietary Supplement: Placebo (for nutritional beverage and probiotic)
Sponsor:   United States Army Research Institute of Environmental Medicine
Completed

Mon, 03 Feb 2014 12:00:00 EST

Exercise and NO in HFrEF

Condition:   Heart Failure With Reduced Ejection Fraction
Interventions:   Dietary Supplement: Antioxidant;   Dietary Supplement: Tetrahydrobiopterin (BH4);   Other: Exercise training
Sponsors:   VA Office of Research and Development;   University of Utah
Recruiting

Tue, 02 May 2017 12:00:00 EDT

Impact of Nuun Instant on Hydration Status in Active Men and Women

Condition:   Hydration
Interventions:   Dietary Supplement: Nuun Instant;   Other: Water;   Dietary Supplement: Nuun Electrolyte
Sponsors:   University of Memphis;   Nuun & Company
Completed

Sun, 21 Feb 2021 12:00:00 EST

Effect of Micronutrients and Exercise During Pregnancy on Factors Related With Non-Transmissible Chronic Diseases

Conditions:   Preeclampsia;   Pregnancy;   Micronutrients;   Exercise
Interventions:   Behavioral: Regular aerobic physical exercise;   Dietary Supplement: Micronutrients;   Other: Activities of daily living + placebo
Sponsors:   Universidad del Valle, Colombia;   Fundación FES;   Fundación Cardiovascular de Colombia;   Instituto Nacional de Salud;   University College, London
Completed

Tue, 31 Mar 2009 12:00:00 EDT

Effect of Timing of Micronutrient Powder Consumption on Iron Absorption in Infants

Conditions:   Anemia;   Iron Deficiency
Interventions:   Dietary Supplement: Fortified maize porridge (MNP and Iron);   Dietary Supplement: Fortified Maize porridge (MNP + Iron + GOS)
Sponsors:   Swiss Federal Institute of Technology;   Jomo Kenyatta University of Agriculture and Technology;   Msambweni County Referral Hospital
Completed

Mon, 12 Dec 2016 12:00:00 EST

Hesperidin and Bone Health in Postmenopausal Women

Condition:   Osteoporosis, Postmenopausal
Interventions:   Dietary Supplement: Hesperidin and Calcilock;   Dietary Supplement: Hesperidin;   Dietary Supplement: Control
Sponsors:   Purdue University;   Nestec Ltd.
Completed

Wed, 19 Jun 2013 12:00:00 EDT

Trial of Pre-Pregnancy Supplements

Condition:   Anemia
Interventions:   Dietary Supplement: Multivitamins, Folic Acid, and Iron;   Dietary Supplement: Folic Acid and Iron;   Dietary Supplement: Folic Acid
Sponsors:   Harvard School of Public Health;   Ifakara Health Institute
Completed

Tue, 17 Aug 2010 12:00:00 EDT

The Intervention of Multi-vitamin With Minerals to Hyperuricemia

Condition:   Hyperuricemia
Interventions:   Combination Product: High-dose multi-vitamins with minerals;   Combination Product: Low-dose multi-vitamins with minerals;   Combination Product: Hypouricemic tablets;   Combination Product: Placebo
Sponsor:   Sun Yat-sen University
Unknown status

Fri, 14 Jul 2017 12:00:00 EDT

Effect of Retaron® on Oxygen Induced Retinal Vasoconstriction in LPS Induced Inflammatory Model in Humans

Conditions:   Imparied Retinal Vascular Reactivity;   Healthy Subjects
Interventions:   Drug: Escherichia coli Endotoxin;   Dietary Supplement: Retaron®;   Other: Placebo
Sponsor:   Medical University of Vienna
Completed

Wed, 20 Aug 2014 12:00:00 EDT

A Study Of Nutraceutical Drinks For Cholesterol (Evaluating Effectiveness and Tolerability)

Condition:   Hyperlipidemia
Interventions:   Dietary Supplement: Placebo;   Dietary Supplement: Second Formulation;   Dietary Supplement: Third Formulation
Sponsor:   Healthy Drink Discoveries, Inc.
Completed

Tue, 29 Jun 2010 12:00:00 EDT

Early Child Development and Nutrition in Guatemala

Condition:   Undernutrition
Interventions:   Dietary Supplement: Micronutrients;   Behavioral: Responsive feeding;   Dietary Supplement: Placebo
Sponsors:   University of Maryland, Baltimore;   Association for the Study and Prevention of HIV/AIDS
Completed

Thu, 27 Nov 2014 12:00:00 EST

Evaluating Whole Foods Supplementation on Cognition

Conditions:   Sub-optimal Cognitive Function;   Sub-optimal Immune Function
Interventions:   Dietary Supplement: Ginkgo Synergy® and Choline;   Dietary Supplement: OPC Synergy® and Catalyn;   Dietary Supplement: Placebo
Sponsors:   University of Miami;   Standard Process Inc.
Completed

Fri, 24 Aug 2012 12:00:00 EDT

Effects of Dietary Antioxidants on Cardiovascular Risk Factors

Conditions:   Obesity;   Hyperlipidemia;   Hypertension
Interventions:   Behavioral: Antioxidant diet;   Dietary Supplement: Antioxidant supplement;   Dietary Supplement: Placebo
Sponsors:   Christopher Gardner;   National Center for Complementary and Integrative Health (NCCIH)
Completed

Mon, 22 Sep 2008 12:00:00 EDT

Microneedling Plus the Universal Peel For Acne Scarring

Condition:   Acne Scarring
Interventions:   Drug: Universal Peel;   Procedure: Microneedling;   Drug: Post-Microneedling Skin Care;   Drug: Post-Universal Peel Skin Care
Sponsors:   Englewood Hospital and Medical Center;   Topix Pharmaceuticals;   Eclipse Aesthetics
Completed

Wed, 25 Jun 2014 12:00:00 EDT

Trial of Vitamins in HIV Progression and Transmission

Conditions:   HIV Infections;   Disease Transmission, Vertical
Interventions:   Dietary Supplement: Vitamin A + Beta Carotene;   Dietary Supplement: Multivitamins;   Other: Placebo
Sponsors:   Harvard School of Public Health;   Muhimbili University of Health and Allied Sciences
Completed

Tue, 20 Sep 2005 12:00:00 EDT

Micronutrient Supplementation in in Paediatric Pulmonary Tuberculosis

Condition:   Tuberculosis
Interventions:   Drug: Zinc;   Drug: Micronutrient without zinc;   Drug: Micronutrient with zinc;   Drug: Placebo
Sponsors:   All India Institute of Medical Sciences, New Delhi;   University of Bergen
Completed

Wed, 03 Dec 2008 12:00:00 EST

Prebiotic GOS and Lactoferrin With Iron Supplements

Condition:   Iron-deficiency
Interventions:   Dietary Supplement: Galacto-oligosaccharides;   Dietary Supplement: Bovine lactoferrin;   Dietary Supplement: Multiple micronutrient powders with 5 mg iron
Sponsors:   Columbia University;   Swiss Federal Institute of Technology;   Jomo Kenyatta University of Agriculture and Technology;   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Recruiting

Thu, 07 Mar 2019 12:00:00 EST

Vitamins, Breastmilk HIV Shedding, and Child Health

Condition:   Maternal and Child Health Outcomes
Interventions:   Dietary Supplement: Vitamin A alone;   Dietary Supplement: Multivitamins excluding vitamin A;   Dietary Supplement: multivitamins including vitamin A;   Other: Placebo
Sponsors:   Harvard School of Public Health;   Muhimbili University of Health and Allied Sciences
Completed

Tue, 20 Sep 2005 12:00:00 EDT

Arterial Disease Multifactorial Intervention Trial (ADMIT)

Conditions:   Arterial Occlusive Diseases;   Cardiovascular Diseases;   Heart Diseases;   Vascular Diseases;   Diabetes Mellitus
Interventions:   Drug: niacin;   Drug: pravastatin;   Drug: beta-carotene;   Drug: vitamin E;   Behavioral: dietary supplements;   Drug: vitamin C;   Drug: warfarin
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Completed

Thu, 28 Oct 1999 12:00:00 EDT

Assessment the Activity Value of Isotretinoin (13- Cis-Retinoic Acid ) in the Treatment of COVID-19 ( Isotretinoin in Treatment of COVID-19) (Randomized)

Condition:   COVID19
Interventions:   Drug: Drug Isotretinoin (13 cis retinoic acid ) capsules+standard treatment;   Drug: Isotretinoin(Aerosolized 13 cis retinoic acid) +standard treatment;   Drug: Isotretinoin (13 cis retinoic acid ) capsules;   Drug: Aerosolized 13 cis retinoic acid;   Drug: Standard treatment
Sponsors:   Kafrelsheikh University;   1-Foshan University Laboratory of Emerging Infectious Disease Institute of Translational Medicine The First Hospital of Jilin University China;   2-Montefiore Health System and Albert Einstein College of Medicine, Newyork, United States of America (U.S.A).;   2-Faculty of Science, Kafrelsheikh University, Egypt.
Not yet recruiting

Mon, 20 Apr 2020 12:00:00 EDT

Trial of Glutamine and Antioxidant Supplementation in Critically Ill Patients

Conditions:   Critical Illness;   Sepsis;   Multiple Organ Failure
Interventions:   Other: Glutamine;   Other: Antioxidants;   Other: Glutamine + Antioxidants;   Other: Placebo
Sponsors:   Daren K. Heyland;   Fresenius Kabi
Completed

Wed, 24 Aug 2005 12:00:00 EDT

Prospective Pilot Trial to Assess a Multimodal Molecular Targeted Therapy in Children, Adolescent and Young Adults With Relapsed or Refractory High-grade Pineoblastoma

Condition:   Pineoblastoma
Interventions:   Drug: Temozolomide;   Drug: Irinotecan;   Drug: Dasatinib;   Drug: Rapamycin
Sponsor:   University of Regensburg
Completed

Wed, 04 Nov 2015 12:00:00 EST

Chronic Study on Body Composition, Training, Performance, and Recovery

Conditions:   Damage Muscle;   Body Weight Changes;   Performance Enhancing Product Use
Interventions:   Dietary Supplement: Pre-workout plus and Protein recovery plus;   Other: Placebo;   Other: 6-week resistance training program
Sponsors:   Pharmanex;   University of North Carolina, Chapel Hill
Active, not recruiting

Sat, 18 Jan 2020 12:00:00 EST

Impact of Behavior Change Communications and Market-based Approach to Delivering Micronutrient Powders on Stunting, Infant Feeding Practices and Anemia in Bangladesh

Conditions:   Child Malnutrition;   Breastfeeding;   Complementary Feeding;   Childhood Anemia
Interventions:   Behavioral: EHC + BCC;   Dietary Supplement: Micronutrient powders;   Behavioral: Mass media
Sponsor:   International Food Policy Research Institute
Completed

Wed, 05 Sep 2012 12:00:00 EDT

A Clinical Trial to Evaluate the Effectiveness and Safety of Chinese Medicine in the Treatment of Mild Type of Hand, Foot, and Mouth Disease

Condition:   Hand, Foot and Mouth Disease
Interventions:   Other: Western therapy;   Drug: TCM Syndrome Differentiation and Treatment;   Other: Western therapy plus TCM treatment
Sponsors:   The First Affiliated Hospital of Anhui University of Traditional Chinese Medicine;   Beijing University of Chinese Medicine;   China Academy of Chinese Medical Sciences
Completed

Tue, 17 Aug 2010 12:00:00 EDT

A Clinical Trial to Evaluate the Effectiveness and Safety of Xiyanping Injection in the Treatment of Mild Type of Hand, Foot, and Mouth Disease

Condition:   Hand, Foot and Mouth Disease
Interventions:   Other: Western therapy;   Drug: Xiyanping Injection;   Drug: Xiyanping Injection with western medicine
Sponsors:   The First Affiliated Hospital of Anhui University of Traditional Chinese Medicine;   Beijing University of Chinese Medicine;   China Academy of Chinese Medical Sciences
Unknown status

Mon, 16 Aug 2010 12:00:00 EDT

Chinese Medicinal Treatment on Mild Hand, Foot, and Mouth Disease: Multicenter, Prospective, Randomized Double-blind, Placebo-controlled Study

Condition:   Hand, Foot and Mouth Disease
Interventions:   Drug: Western therapy;   Drug: JET;   Drug: Placebo(for JET)
Sponsors:   China Academy of Chinese Medical Sciences;   Chengdu University of Traditional Chinese Medicine;   Beijing Children's Hospital;   Tianjin infectious disease hospital;   Tangshan infectious disease hospital;   The First Affiliated Hospital of Anhui University of Traditional Chinese Medicine;   Tianjin Zhongshenghaitian Pharmaceutical Co. Ltd.
Completed

Thu, 17 Jan 2013 12:00:00 EST

The Effect of Lysulin on Glycemic Control and Advanced Glycation

Condition:   Type 2 Diabetes
Intervention:   Dietary Supplement: Lysulin
Sponsor:   Juraj Koska
Terminated

Tue, 21 Jan 2020 12:00:00 EST

Efficacy of Topical Antioxidants in Tretment of Photoaging

Condition:   Photoaging
Intervention:   Drug: Selenium Amino Acid Chelate (Selenium ACE cream)
Sponsor:   Sohag University
Not yet recruiting

Thu, 08 Apr 2021 12:00:00 EDT

Study of the Ability of Clarithromycin to Induce Oxidative Stress

Condition:   Oxidative Stress
Intervention:   Drug: Clarithromycin
Sponsor:   Rigshospitalet, Denmark
Completed

Mon, 30 Jun 2008 12:00:00 EDT

Effectiveness of a Nutraceutical in Raising Circulating Serum Vitamin, Mineral and Amino Acid Levels in Patients.

Condition:   Vitamin Deficiency
Interventions:   Dietary Supplement: EZPAK;   Dietary Supplement: Placebo
Sponsor:   Optimal Health Research
Completed

Tue, 13 Aug 2019 12:00:00 EDT

Stereotactic Body Radiation Therapy in Treating Patients With Localized Prostate Cancer That Have Undergone Surgery

Conditions:   PSA Level Greater Than 0.03;   PSA Progression;   Stage I Prostate Adenocarcinoma AJCC (American Joint Committee on Cancer ) v7;   Stage II Prostate Adenocarcinoma AJCC v7;   Stage III Prostate Adenocarcinoma AJCC v7
Interventions:   Drug: Antiandrogen Therapy;   Other: Quality-of-Life Assessment;   Radiation: Stereotactic Body Radiation Therapy
Sponsors:   Jonsson Comprehensive Cancer Center;   Viewray Inc.
Recruiting

Thu, 31 May 2018 12:00:00 EDT

Treatment of Advanced Hepatocellular Carcinoma

Condition:   HCC
Interventions:   Other: Basic drugs therapy of HCC;   Drug: Arginine hydrochloride;   Drug: Trimetazidine hydrochloride
Sponsors:   The First Affiliated Hospital of Zhengzhou University;   First Affiliated Hospital of Xinjiang Medical University;   Jiaozuo third people's hospital;   Luoyang Central Hospital;   Nanyang Central Hospital;   Anyang Tumor Hospital;   Pingmei Shenma Medical Group General Hospital;   First People's Hospital of Shangqiu
Unknown status

Mon, 11 Sep 2017 12:00:00 EDT

Treatment of Intermediate-stage Hepatocellular Carcinoma

Condition:   HCC
Interventions:   Device: Basic drugs therapy of HCC by TACE;   Drug: Arginine hydrochloride;   Drug: Trimetazidine hydrochloride
Sponsors:   The First Affiliated Hospital of Zhengzhou University;   First Affiliated Hospital of Xinjiang Medical University;   Luoyang Central Hospital;   Nanyang Central Hospital;   Anyang Tumor Hospital;   Shenma Medical Group General Hospital;   First People's Hospital of Shangqiu;   Jiaozuo third people's hospital
Unknown status

Thu, 07 Sep 2017 12:00:00 EDT

Comparison of Two Nutrition Interventions in Young Children in El Salvador

Condition:   Micronutrient Deficiency
Interventions:   Dietary Supplement: 21 micronutrient-fortified supplement;   Dietary Supplement: Cereal Fortificado (Fortified Cereal);   Dietary Supplement: Ferrous sulphate;   Dietary Supplement: Vitamin A
Sponsors:   The Mathile Institute for the Advancement of Human Nutrition;   Fundación Salvadoreña para la Salud y el Desarrollo Humano;   Humanitas Global Development;   Ministry of Health, El Salvador
Active, not recruiting

Mon, 05 Oct 2015 12:00:00 EDT

PLX3397, Radiation Therapy, and Antihormone Therapy in Treating Patients With Intermediate- or High-Risk Prostate Cancer

Conditions:   Stage I Prostate Adenocarcinoma;   Stage II Prostate Adenocarcinoma;   Stage III Prostate Adenocarcinoma
Interventions:   Drug: Antiandrogen Therapy;   Other: Laboratory Biomarker Analysis;   Drug: Multitargeted Tyrosine Kinase Inhibitor PLX3397;   Radiation: Radiation Therapy
Sponsors:   Barbara Ann Karmanos Cancer Institute;   National Cancer Institute (NCI)
Completed

Mon, 15 Jun 2015 12:00:00 EDT

Observational Study on the Use of Ivermectin as an Outpatient Treatment Option for COVID-19

Conditions:   Covid19;   COVID-19 Pneumonia;   COVID-19 Respiratory Infection;   COVID-19 Acute Bronchitis
Intervention:   Drug: Ivermectin
Sponsor:   Patrick Robinson
Not yet recruiting

Thu, 16 Sep 2021 12:00:00 EDT

Evaluating the Impact of the Food Support Program (Programa de Apoyo Alimentaria)

Condition:   Malnutrition
Interventions:   Other: Cash + nutrition education;   Other: Food basket + nutrition education;   Other: Food basket w/o nutrition education;   Other: Control
Sponsors:   Instituto Nacional de Salud Publica, Mexico;   Secretaría de Desarrollo Social (SEDESOL)
Completed

Mon, 28 Feb 2011 12:00:00 EST

Prospective Evaluation of Taste Function In Multiple Myeloma Patients Undergoing Autologous Hematopoietic Cell Transplantation

Condition:   Multiple Myeloma
Interventions:   Diagnostic Test: Oral microbiota assessment;   Diagnostic Test: Comprehensive chemical gustometry;   Diagnostic Test: Measurement of salivary flow;   Behavioral: Surveys assessing taste disturbances
Sponsor:   Memorial Sloan Kettering Cancer Center
Active, not recruiting

Fri, 08 Sep 2017 12:00:00 EDT

C Reactive Protein in Home Quarantined Coronavirus Disease 2019 (COVID -19) Patients.

Condition:   COVID -19
Interventions:   Drug: Oral Antibiotic, Antihistamine, Anti-inflammatory, Multivitamins;   Drug: Oral low dose steroid;   Drug: Intravenous Antibiotics with Low dose steroid.;   Drug: Oral anti-coagulant
Sponsors:   Manimarane Arjunan, MD,DM (Cardiology);   UR Anoop Research Group
Completed

Wed, 23 Jun 2021 12:00:00 EDT

Efficacy and Safety of Standard Oral Colonoscopic Preparations With or Without Neostigmine Compared to Pulse-Irrigation Colonic Lavage

Condition:   Spinal Cord Injury
Intervention:   Drug: Neostigmine
Sponsor:   US Department of Veterans Affairs
Completed

Wed, 03 Sep 2008 12:00:00 EDT

Prevention of Intrauterine Growth Retardation in Burkina Faso: the Malaria Component

Conditions:   Malaria;   Malaria in Pregnancy
Interventions:   Dietary Supplement: Multiple micronutrients supplements (MMS);   Dietary Supplement: Iron and folic acid (IFA);   Drug: Chloroquine (CQ);   Drug: Sulphadoxyne-pyrimethamine (SP)
Sponsors:   Institute of Tropical Medicine, Belgium;   Departments of Parasitology and Public Health, ITM, Antwerp, Belgium;   Centre Muraz;   Laboratoire National de Santé Publique, Ouagadougou, Burkina Faso
Completed

Tue, 20 May 2008 12:00:00 EDT

Androgen Ablation Therapy With or Without Niraparib After Radiation Therapy for the Treatment of High-Risk Localized or Locally Advanced Prostate Cancer

Conditions:   Prostate Carcinoma;   Stage IIC Prostate Cancer AJCC v8;   Stage III Prostate Cancer AJCC v8;   Stage IIIA Prostate Cancer AJCC v8;   Stage IIIB Prostate Cancer AJCC v8;   Stage IIIC Prostate Cancer AJCC v8;   Stage IVA Prostate Cancer AJCC v8
Interventions:   Drug: Abiraterone Acetate;   Drug: Antiandrogen Therapy;   Drug: Apalutamide;   Procedure: Biopsy;   Drug: Niraparib;   Drug: Prednisone;   Radiation: Radiation Therapy
Sponsor:   M.D. Anderson Cancer Center
Recruiting

Thu, 01 Jul 2021 12:00:00 EDT

Advanced ChemoHormonal Therapy for Treatment Naive Metastatic Prostate Cancer

Conditions:   Castration-Sensitive Prostate Carcinoma;   Metastatic Prostate Carcinoma;   Stage IV Prostate Cancer AJCC v8;   Stage IVA Prostate Cancer AJCC v8;   Stage IVB Prostate Cancer AJCC v8
Interventions:   Drug: Abiraterone Acetate;   Drug: Antiandrogen Therapy;   Drug: Apalutamide;   Drug: Prednisone;   Other: Quality-of-Life Assessment;   Other: Questionnaire Administration
Sponsors:   OHSU Knight Cancer Institute;   Janssen Scientific Affairs, LLC;   Oregon Health and Science University
Recruiting

Thu, 13 Feb 2020 12:00:00 EST

Docetaxel or Abiraterone Acetate With ADT in Treating Patients With Metastatic Hormone Sensitive Prostate Cancer

Conditions:   Castration-Sensitive Prostate Carcinoma;   Metastatic Prostatic Adenocarcinoma;   Stage IV Prostate Cancer;   Stage IVA Prostate Cancer;   Stage IVB Prostate Cancer
Interventions:   Drug: Abiraterone Acetate;   Drug: Antiandrogen Therapy;   Drug: Docetaxel;   Drug: Prednisone;   Other: Quality-of-Life Assessment;   Other: Questionnaire Administration
Sponsor:   University of Utah
Terminated

Fri, 01 Feb 2019 12:00:00 EST

Nitrite Infusion Studies

Condition:   Healthy
Interventions:   Drug: Oxypurinol;   Drug: Sodium Nitrite
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Completed

Wed, 26 Jan 2005 12:00:00 EST

Antiandrogen Therapy, Abiraterone Acetate, and Prednisone With or Without Neutron Radiation Therapy in Treating Patients With Prostate Cancer

Conditions:   Castration-Sensitive Prostate Carcinoma;   Metastatic Malignant Neoplasm in the Bone;   Metastatic Prostate Carcinoma;   Prostate Adenocarcinoma;   Prostate Small Cell Neuroendocrine Carcinoma;   Stage IV Prostate Cancer AJCC v8;   Stage IVA Prostate Cancer AJCC v8;   Stage IVB Prostate Cancer AJCC v8
Interventions:   Drug: Antiandrogen Therapy;   Drug: Abiraterone Acetate;   Drug: Prednisone;   Radiation: Radiation Therapy
Sponsors:   University of Washington;   National Cancer Institute (NCI)
Recruiting

Tue, 28 Aug 2018 12:00:00 EDT

Therapeutic Effect of Cytoreductive Radical Prostatectomy in Men With Newly Diagnosed Metastatic Prostate Cancer

Condition:   Stage IV Prostate Adenocarcinoma AJCC v7
Interventions:   Drug: Antiandrogen Therapy;   Drug: Docetaxel;   Other: Laboratory Biomarker Analysis;   Procedure: Quality-of-Life Assessment;   Other: Questionnaire Administration;   Procedure: Radical Prostatectomy
Sponsors:   Rutgers, The State University of New Jersey;   National Cancer Institute (NCI)
Recruiting

Wed, 07 Mar 2018 12:00:00 EST

Abiraterone Acetate and Antiandrogen Therapy With or Without Cabazitaxel and Prednisone in Treating Patients With Metastatic, Castration-Resistant Prostate Cancer Previously Treated With Docetaxel

Conditions:   Castration Levels of Testosterone;   Castration-Resistant Prostate Carcinoma;   Metastatic Prostate Carcinoma in the Soft Tissue;   Prostate Carcinoma Metastatic in the Bone;   Stage IV Prostate Adenocarcinoma AJCC v7
Interventions:   Drug: Abiraterone Acetate;   Drug: Antiandrogen Therapy;   Drug: Cabazitaxel;   Other: Laboratory Biomarker Analysis;   Procedure: Orchiectomy;   Other: Pharmacological Study;   Drug: Prednisone
Sponsors:   ECOG-ACRIN Cancer Research Group;   National Cancer Institute (NCI)
Recruiting

Thu, 01 Feb 2018 12:00:00 EST

Renal Metabolism of Glycolate to Oxalate

Condition:   Healthy
Interventions:   Dietary Supplement: Low oxalate controlled Diet;   Other: Primed, continuous intravenous infusion of 13C2-Glycolate;   Other: Bolus intravenous infusion of 13C2-Glycolate;   Other: Oral bolus administration of 13C2-Glycolate
Sponsor:   University of Alabama at Birmingham
Recruiting

Thu, 18 Jun 2020 12:00:00 EDT

Pembrolizumab +/- SD-101 in Hormone-Naïve Oligometastatic Prostate Cancer With RT and iADT

Condition:   Prostatic Neoplasms
Interventions:   Drug: Pembrolizumab;   Drug: SD-101;   Drug: Leuprolide acetate;   Drug: Abiraterone Acetate;   Drug: Prednisone;   Radiation: Stereotactic Body Radiation Therapy
Sponsors:   Lawrence Fong;   Prostate Cancer Foundation;   Merck Sharp & Dohme Corp.;   Dynavax Technologies Corporation
Recruiting

Mon, 02 Jan 2017 12:00:00 EST

Exercise in Health and Chronic Obstructive Pulmonary Disease

Condition:   Chronic Obstructive Pulmonary Disease
Interventions:   Other: Knee-extensor exercise test;   Other: Exercise test with restricting/releasing blood flow;   Other: Exercise test with variable oxygen concentration and MRI;   Other: Exercise test with oral antioxidant or placebo cocktail
Sponsor:   University of Utah
Completed

Mon, 24 Nov 2014 12:00:00 EST

External Beam Radiation With or Without Chemotherapy to Treat High Risk Prostate Cancer

Condition:   Prostate Cancer
Interventions:   Drug: Luteinizing hormone-releasing hormone (LHRH);   Drug: Docetaxel;   Other: Conformal Radiation Therapy (RT)
Sponsor:   Proton Collaborative Group
Terminated

Tue, 22 May 2012 12:00:00 EDT

Antiandrogen Therapy With or Without Axitinib Before Surgery in Treating Patients With Previously Untreated Prostate Cancer With Known or Suspected Lymph Node Metastasis

Conditions:   Metastatic Malignant Neoplasm in Lymph Node;   Prostate Ductal Adenocarcinoma;   Stage III Prostate Adenocarcinoma AJCC v7;   Stage IV Prostate Adenocarcinoma AJCC v7
Interventions:   Drug: Antiandrogen Therapy;   Drug: Axitinib;   Procedure: Radical Prostatectomy;   Procedure: Regional Lymph Node Dissection
Sponsors:   M.D. Anderson Cancer Center;   National Cancer Institute (NCI)
Active, not recruiting

Thu, 04 Aug 2011 12:00:00 EDT

Study of Lanreotide in Non Metastatic Castration-resistant Prostate Cancer Patients

Condition:   Prostate Cancer
Interventions:   Drug: Lanreotide, non steroidal anti androgens and LHRH-a;   Drug: Non steroidal anti androgens and LHRH-a
Sponsor:   Ipsen
Terminated

Fri, 11 Mar 2011 12:00:00 EST

Effect of Antioxidants on Ocular Blood Flow, Endothelial Function, and Cytokine Levels in LPS Induced Inflammatory Model in Humans.

Conditions:   Retina;   Regional Blood Flow;   Endotoxin, Escherichia Coli
Interventions:   Drug: vitamin and mineral supplement;   Drug: Escherichia coli Endotoxin (LPS);   Drug: 100% O2;   Drug: nitroglycerin
Sponsor:   Medical University of Vienna
Completed

Tue, 06 Feb 2007 12:00:00 EST

Samarium-153 With Neoadjuvant Hormonal and Radiation Therapy for Locally Advanced Prostate Cancer

Condition:   Prostate Cancer
Interventions:   Drug: Samarium-153;   Drug: Total Androgen Suppression (TAS) with Bicalutamide;   Drug: Total androgen suppression (TAS) with Goserelin Acetate;   Device: Radiation Therapy
Sponsors:   Sidney Kimmel Cancer Center at Thomas Jefferson University;   Cytogen Corporation
Completed

Mon, 22 May 2006 12:00:00 EDT

Androgen Suppression Combined With Elective Nodal and Dose Escalated Radiation Therapy

Condition:   Prostate Cancer
Interventions:   Procedure: Androgen suppression, radiotherapy;   Procedure: Androgen suppression, radiotherapy, iodine 125 brachytherapy
Sponsor:   University of British Columbia
Unknown status

Thu, 15 Sep 2005 12:00:00 EDT

Pharmacodynamic Evaluation of Stool Output Following Oral Administration of Various Low Volume PEG3350-based Gut Cleansing Solutions Using the Split Dose Intake in Healthy Subjects

Condition:   Colorectal Cancer
Interventions:   Drug: NER1006;   Drug: Moviprep
Sponsors:   Norgine;   Pierrel Research Europe GmbH
Completed

Thu, 18 Apr 2013 12:00:00 EDT

Oxidative Stress In Semen And Male Infertility

Conditions:   Antioxidants;   Infertility, Male;   Semen Quality
Interventions:   Drug: Fairhaven Pro for men;   Diagnostic Test: Semen analysis;   Diagnostic Test: Sperm DNA fragmentation;   Diagnostic Test: Static Oxidation reduction potential in semen
Sponsors:   Hamad Medical Corporation;   Fairhaven Health
Unknown status

Wed, 14 Mar 2018 12:00:00 EDT

Front-of-package Marketing on Fruit Drinks: Online RCT

Conditions:   Consumer Behavior;   Consumer Preference
Intervention:   Behavioral: front-of-package modification
Sponsors:   Harvard School of Public Health;   Robert Wood Johnson Foundation
Completed

Tue, 23 Mar 2021 12:00:00 EDT

Impact of Ursodeoxycholic Acid, Silymarin, Antioxidants and Colchicine on Fibrosis Regression in HCV After SVR

Condition:   Fibrosis, Liver
Interventions:   Drug: silymarin;   Drug: Ursodeoxycholic Acid;   Drug: Antioxidants;   Drug: Colchicine;   Other: FOLLOW UP
Sponsor:   Zagazig University
Completed

Thu, 06 Sep 2018 12:00:00 EDT

Testing of a Candy in Five Different Versions for the Additional Humidification of the Oral Cavity

Conditions:   Xerostomia;   Dryness of Mouth
Interventions:   Other: V01 candy;   Other: V02 candy;   Other: V03 candy;   Other: V04 candy;   Other: V05 candy
Sponsor:   University Hospital, Basel, Switzerland
Completed

Fri, 18 Sep 2020 12:00:00 EDT

Effect of Antioxidants on Oxygen Induced Vasoconstriction in Lipopolysaccharide (LPS) Induced Inflammatory Model in Humans

Condition:   Healthy
Interventions:   Drug: Vitamin and mineral supplement;   Drug: Placebo;   Drug: 100% Oxygen;   Drug: Escherichia coli Endotoxin
Sponsor:   Medical University of Vienna
Completed

Fri, 05 Jun 2009 12:00:00 EDT

NutFish and Nutrient Supplementation in Pregnancy Class to Improve Maternal and Birth Outcomes

Conditions:   Pregnancy;   Protein-Energy Malnutrition;   Anemia
Interventions:   Other: NutFish Based Food Supplementation;   Dietary Supplement: Multiple micronutrients;   Behavioral: Health Education in Pregnancy Class;   Other: Government Food Supplementation;   Dietary Supplement: Fe Supplementation
Sponsor:   Semarang Health Polytechnic
Unknown status

Tue, 08 Nov 2016 12:00:00 EST

Multimodal Molecular Targeted Therapy to Treat Relapsed or Refractory High-risk Neuroblastoma

Condition:   Neuroblastoma Recurrent
Interventions:   Drug: Dasatinib;   Drug: Rapamycin;   Drug: Irinotecan;   Drug: Temozolomide
Sponsor:   University of Regensburg
Completed

Wed, 09 Nov 2011 12:00:00 EST

Impact Evaluation of the DFID Programme to Accelerate Improved Nutrition of the Extreme Poor in Bangladesh

Conditions:   Child Nutritional Status;   Household Dietary Diversity;   Maternal Nutrition Knowledge and Practices
Interventions:   Behavioral: CLP: Livelihoods;   Dietary Supplement: CLP: Nutrition;   Behavioral: Shiree: Livelihoods;   Dietary Supplement: Shiree: Nutrition;   Behavioral: UPPR: Livelihoods;   Dietary Supplement: UPPR: Nutrition;   Other: UPPR: Control
Sponsors:   International Food Policy Research Institute;   Department for International Development, United Kingdom;   Institute of Development Studies;   Chars Livelihoods Programme;   Shiree, Stimulating Household Improvements Resulting in Economic Empowerment;   Urban Partnerships for Poverty Reduction;   Consortium of International Agricultural Research Centers
Completed

Thu, 05 Nov 2015 12:00:00 EST

Studying the Impact of Product Packaging in a Virtual Store Environment

Condition:   Obesity, Childhood
Interventions:   Behavioral: Experimental Drink: Nutrition claim on fruit drinks;   Behavioral: Control Drink: No nutrition claim;   Behavioral: Experimental snack: Text warning;   Behavioral: Experimental snack: Graphic warning;   Behavioral: Control snack: barcode label
Sponsors:   University of North Carolina, Chapel Hill;   Robert Wood Johnson Foundation;   National Heart, Lung, and Blood Institute (NHLBI)
Completed

Fri, 08 May 2020 12:00:00 EDT

Zinc-MNP Trial for Prevention of Diarrhea and Promotion of Linear Growth

Conditions:   Diarrhea;   Stunting
Interventions:   Dietary Supplement: Standard MNP;   Dietary Supplement: High zinc, low iron MNP;   Dietary Supplement: High zinc, low/no iron on alternating days;   Dietary Supplement: Dispersible zinc supplement;   Dietary Supplement: Intermittent zinc supplement;   Dietary Supplement: Placebo powder
Sponsors:   UCSF Benioff Children's Hospital Oakland;   International Centre for Diarrhoeal Disease Research, Bangladesh;   Johns Hopkins Bloomberg School of Public Health;   University of Colorado, Denver
Completed

Tue, 23 Jan 2018 12:00:00 EST