Summary of Use during Lactation

No information is available on the use of asparaginase during breastfeeding. . Because aspariginase is a large protein molecule with a molecular weight of about 140,000 Da, the amount in milk is likely to be very low and absorption is unlikely because it is probably destroyed in the infant's gastrointestinal tract. However, the manufacturer recommends that breastfeeding be discontinued during asparaginase therapy and for 3 months after the final dose.

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

Substance Name

Asparaginase

CAS Registry Number

CASRN: 9015-68-3

Drug Class

Breast Feeding

Lactation

Antineoplastic Agents

Enzymes