Full text biomedical articles

Aspirin or heparin or both for improving pregnancy outcomes in women with persistent antiphospholipid antibodies and recurrent pregnancy loss

Cochrane Database Syst Rev. 2020 May; 2020(5): CD012852. Published online 2020 May 2. doi: 10.1002/14651858.CD012852.pub2

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Associations between aspirin use and the risk of cancers: a meta-analysis of observational studies

Yan Qiao, Tingting Yang, Yong Gan, Wenzhen Li, Chao Wang, Yanhong Gong, Zuxun Lu
BMC Cancer. 2018; 18: 288. Published online 2018 Mar 13. doi: 10.1186/s12885-018-4156-5

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A Proteomic Approach to Analyze the Aspirin-mediated Lysine Acetylome

Michael H. Tatham, Christian Cole, Paul Scullion, Ross Wilkie, Nicholas J. Westwood, Lesley A. Stark, Ronald T. Hay
Mol Cell Proteomics. 2017 Feb; 16(2): 310–326. Published online 2016 Dec 5. doi: 10.1074/mcp.O116.065219

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Effects of aspirin on risks of vascular events and cancer according to bodyweight and dose: analysis of individual patient data from randomised trials

Peter M Rothwell, Nancy R Cook, J Michael Gaziano, Jacqueline F Price, Jill F F Belch, Maria Carla Roncaglioni, Takeshi Morimoto, Ziyah Mehta
Lancet. 2018 Aug 4; 392(10145): 387–399. doi: 10.1016/S0140-6736(18)31133-4

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Effects of chronic low‐dose aspirin treatment on tumor prevention in three mouse models of intestinal tumorigenesis

Nadine Rohwer, Anja A. Kühl, Annika I. Ostermann, Nicole Marie Hartung, Nils Helge Schebb, Dieter Zopf, Fiona M. McDonald, Karsten‐H. Weylandt
Cancer Med. 2020 Apr; 9(7): 2535–2550. Published online 2020 Jan 29. doi: 10.1002/cam4.2881

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A Systematic Review of Aspirin in Primary Prevention: Is It Time for a New Approach?

Carlos Brotons, Robert Benamouzig, Krzysztof J. Filipiak, Volker Limmroth, Claudio Borghi
Am J Cardiovasc Drugs. 2015; 15(2): 113–133. Published online 2014 Dec 12. doi: 10.1007/s40256-014-0100-5

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Mechanisms of Colorectal Cancer Prevention by Aspirin—A Literature Review and Perspective on the Role of COX-Dependent and -Independent Pathways

Ranjini Sankaranarayanan, D. Ramesh Kumar, Meric A. Altinoz, G. Jayarama Bhat
Int J Mol Sci. 2020 Dec; 21(23): 9018. Published online 2020 Nov 27. doi: 10.3390/ijms21239018

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Aspirin cooperates with p300 to activate the acetylation of H3K9 and promote FasL-mediated apoptosis of cancer stem-like cells in colorectal cancer

Zhigang Chen, Wenlu Li, Fuming Qiu, Qi Huang, Zhou Jiang, Jun Ye, Pu Cheng, Cho Low, Yikun Guo, Xinchi Yi, Wenteng Chen, Yongpin Yu, YueHua Han, Jun Wu, Shenghang Jin, Dong Kong, Jian Huang
Theranostics. 2018; 8(16): 4447–4461. Published online 2018 Aug 7. doi: 10.7150/thno.24284

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Aspirin binds to PPARα to stimulate hippocampal plasticity and protect memory

Dhruv Patel, Avik Roy, Madhuchhanda Kundu, Malabendu Jana, Chi-Hao Luan, Frank J. Gonzalez, Kalipada Pahan
Proc Natl Acad Sci U S A. 2018 Jul 31; 115(31): E7408–E7417. Published online 2018 Jul 16. doi: 10.1073/pnas.1802021115

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Bleeding Risk with Long-Term Low-Dose Aspirin: A Systematic Review of Observational Studies

Luis A. García Rodríguez, Mar Martín-Pérez, Charles H. Hennekens, Peter M. Rothwell, Angel Lanas
PLoS One. 2016; 11(8): e0160046. Published online 2016 Aug 4. doi: 10.1371/journal.pone.0160046

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Beyond COX-1: the effects of aspirin on platelet biology and potential mechanisms of chemoprevention

Argentina Ornelas, Niki Zacharias-Millward, David G. Menter, Jennifer S. Davis, Lenard Lichtenberger, David Hawke, Ernest Hawk, Eduardo Vilar, Pratip Bhattacharya, Steven Millward
Cancer Metastasis Rev. 2017; 36(2): 289–303. Published online 2017 Jul 31. doi: 10.1007/s10555-017-9675-z

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Aspirin and colorectal cancer: the promise of precision chemoprevention

David A. Drew, Yin Cao, Andrew T. Chan
Nat Rev Cancer. Author manuscript; available in PMC 2019 Sep 12.
Published in final edited form as: Nat Rev Cancer. 2016 Mar; 16(3): 173–186. Published online 2016 Feb 12. doi: 10.1038/nrc.2016.4

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Aspirin enhances the sensitivity of colon cancer cells to cisplatin by abrogating the binding of NF-κB to the COX-2 promoter

Wei Jiang, Yue Yan, Manyu Chen, Guangyu Luo, Jiaojiao Hao, Jinjin Pan, Sheng Hu, Ping Guo, Wenyang Li, Ruozu Wang, Yan Zuo, Yao Sun, Silei Sui, Wendan Yu, Zhe Pan, Kun Zou, Zongheng Zheng, Wuguo Deng, Xiaojun Wu, Wei Guo
Aging (Albany NY) 2020 Jan 15; 12(1): 611–627. Published online 2020 Jan 6. doi: 10.18632/aging.102644

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Aspirin Improves Nonalcoholic Fatty Liver Disease and Atherosclerosis through Regulation of the PPARδ-AMPK-PGC-1α Pathway in Dyslipidemic Conditions

Yoon-Mi Han, Yong-Jik Lee, Yoo-Na Jang, Hyun-Min Kim, Hong Seog Seo, Tae Woo Jung, Ji Hoon Jeong
Biomed Res Int. 2020; 2020: 7806860. Published online 2020 Mar 19. doi: 10.1155/2020/7806860

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Association Between Low-Dose Aspirin Use and Colorectal Cancer Incidence in Taiwan

Hui-Min Diana Lin, Pareen Vora, Montse Soriano-Gabarró, K. Arnold Chan
JAMA Netw Open. 2020 Nov; 3(11): e2026494. Published online 2020 Nov 19. doi: 10.1001/jamanetworkopen.2020.26494

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Aspirin Induces Lysosomal Biogenesis and Attenuates Amyloid Plaque Pathology in a Mouse Model of Alzheimer's Disease via PPARα

Sujyoti Chandra, Malabendu Jana, Kalipada Pahan
J Neurosci. 2018 Jul 25; 38(30): 6682–6699. doi: 10.1523/JNEUROSCI.0054-18.2018

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Clopidogrel plus aspirin versus aspirin alone for preventing cardiovascular events

Alessandro Squizzato, Marta Bellesini, Andrea Takeda, Saskia Middeldorp, Marco Paolo Donadini, Cochrane Heart Group
Cochrane Database Syst Rev. 2017 Dec; 2017(12): CD005158. Published online 2017 Dec 14. doi: 10.1002/14651858.CD005158.pub4

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Aspirin in the Treatment of Cancer: Reductions in Metastatic Spread and in Mortality: A Systematic Review and Meta-Analyses of Published Studies

Peter C. Elwood, Gareth Morgan, Janet E. Pickering, Julieta Galante, Alison L. Weightman, Delyth Morris, Mark Kelson, Sunil Dolwani
PLoS One. 2016; 11(4): e0152402. Published online 2016 Apr 20. doi: 10.1371/journal.pone.0152402

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Aspirin (single dose) for perineal pain in the early postpartum period

Sujana Molakatalla, Emily Shepherd, Rosalie M Grivell
Cochrane Database Syst Rev. 2017 Feb; 2017(2): CD012129. Published online 2017 Feb 9. doi: 10.1002/14651858.CD012129.pub2

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Aspirin (single dose) for perineal pain in the early postpartum period

Cochrane Database Syst Rev. 2020 Jul; 2020(7): CD012129. Published online 2020 Jul 24. doi: 10.1002/14651858.CD012129.pub3

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