Full text biomedical articles

Atomoxetine: A Review of Its Pharmacokinetics and Pharmacogenomics Relative to Drug Disposition

Guo Yu, Guo-Fu Li, John S. Markowitz
J Child Adolesc Psychopharmacol. 2016 May 1; 26(4): 314–326. doi: 10.1089/cap.2015.0137

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Quantitative prediction of the bitterness of atomoxetine hydrochloride and taste-masked using hydroxypropyl-β-cyclodextrin: A biosensor evaluation and interaction study

Shuying Li, Ying Zhang, Abdur Rauf Khan, Shuwang He, Yingxin Wang, Jiangkang Xu, Guangxi Zhai
Asian J Pharm Sci. 2020 Jul; 15(4): 492–505. Published online 2019 Nov 26. doi: 10.1016/j.ajps.2019.11.001

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Physiologically Based Pharmacokinetic Model of the CYP2D6 Probe Atomoxetine: Extrapolation to Special Populations and Drug-Drug Interactions

Weize Huang, Mariko Nakano, Jennifer Sager, Isabelle Ragueneau-Majlessi, Nina Isoherranen
Drug Metab Dispos. 2017 Nov; 45(11): 1156–1165. Published online 2017 Nov. doi: 10.1124/dmd.117.076455

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Antihyperalgesic Activity of Atomoxetine on Diabetes-Induced Neuropathic Pain: Contribution of Noradrenergic and Dopaminergic Systems

Mustafa Burak Barbaros, Özgür Devrim Can, Umut İrfan Üçel, Nazlı Turan Yücel, Ümide Demir Özkay
Molecules. 2018 Aug; 23(8): 2072. Published online 2018 Aug 19. doi: 10.3390/molecules23082072

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Atomoxetine improves memory and other components of executive function in young-adult rats and aged rhesus monkeys

Patrick M. Callahan, Marc R. Plagenhoef, David T. Blake, Alvin V. Terry, Jr.
Neuropharmacology. Author manuscript; available in PMC 2020 Sep 1.
Published in final edited form as: Neuropharmacology. 2019 Sep 1; 155: 65–75. Published online 2019 May 18. doi: 10.1016/j.neuropharm.2019.05.016

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Atomoxetine Increased Effect over Time in Adults with Attention‐Deficit/Hyperactivity Disorder Treated for up to 6 Months: Pooled Analysis of Two Double‐Blind, Placebo‐Controlled, Randomized Trials

Linda A. Wietecha, David B. Clemow, Andrew S. Buchanan, Joel L. Young, Elias H. Sarkis, Robert L. Findling
CNS Neurosci Ther. 2016 Jul; 22(7): 546–557. Published online 2016 Feb 28. doi: 10.1111/cns.12533

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Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6 Genotype and Atomoxetine Therapy

Jacob T. Brown, Jeffrey R. Bishop, Katrin Sangkuhl, Erika L. Nurmi, Daniel J. Mueller, Jean C. Dinh, Andrea Gaedigk, Teri E. Klein, Kelly E. Caudle, James T. McCracken, Jose de Leon, J. Steven Leeder
Clin Pharmacol Ther. Author manuscript; available in PMC 2020 Jul 1.
Published in final edited form as: Clin Pharmacol Ther. 2019 Jul; 106(1): 94–102. Published online 2019 Apr 13. doi: 10.1002/cpt.1409

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Pharmacokinetic Profile and Palatability of Atomoxetine Oral Solution in Healthy Japanese Male Adults

Masako Nakano, Jennifer Witcher, Yoichi Satoi, Taro Goto
Clin Drug Investig. 2016; 36(11): 903–911. Published online 2016 Jul 21. doi: 10.1007/s40261-016-0430-y

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Neural correlates of atomoxetine improving inhibitory control and visual processing in Drug‐naïve adults with attention‐deficit/hyperactivity disorder

Li‐Ying Fan, Tai‐Li Chou, Susan Shur‐Fen Gau
Hum Brain Mapp. 2017 Oct; 38(10): 4850–4864. Published online 2017 Jun 28. doi: 10.1002/hbm.23683

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Blockade of α2-adrenergic receptors in prelimbic cortex: Impact on cocaine self-administration in adult Spontaneously Hypertensive Rats following adolescent atomoxetine treatment

Britahny M. Baskin, Bríd Á. Nic Dhonnchadha, Linda P. Dwoskin, Kathleen M. Kantak
Psychopharmacology (Berl) Author manuscript; available in PMC 2018 Oct 1.
Published in final edited form as: Psychopharmacology (Berl). 2017 Oct; 234(19): 2897–2909. Published online 2017 Jul 20. doi: 10.1007/s00213-017-4681-y

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The effect of atomoxetine, a selective norepinephrine reuptake inhibitor, on respiratory arrest and cardiorespiratory function in the DBA/1 mouse model of SUDEP

Haiting Zhao, Joseph F. Cotten, Xiaoyan Long, Hua-Jun Feng
Epilepsy Res. Author manuscript; available in PMC 2018 Nov 1.
Published in final edited form as: Epilepsy Res. 2017 Nov; 137: 139–144. Published online 2017 Aug 24. doi: 10.1016/j.eplepsyres.2017.08.005

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Physiologically based pharmacokinetic modelling of atomoxetine with regard to CYP2D6 genotypes

Se-Hyung Kim, Ji-Young Byeon, Young-Hoon Kim, Choong-Min Lee, Yun Jeong Lee, Choon-Gon Jang, Seok-Yong Lee
Sci Rep. 2018; 8: 12405. Published online 2018 Aug 17. doi: 10.1038/s41598-018-30841-8

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Dextroamphetamine (but Not Atomoxetine) Induces Reanimation from General Anesthesia: Implications for the Roles of Dopamine and Norepinephrine in Active Emergence

Jonathan D. Kenny, Norman E. Taylor, Emery N. Brown, Ken Solt
PLoS One. 2015; 10(7): e0131914. Published online 2015 Jul 6. doi: 10.1371/journal.pone.0131914

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Determination of Atomoxetine or Escitalopram in human plasma by HPLC. Applications in Neuroscience Research Studies

Jens Teichert, James B Rowe, Karen D Ersche, Nikolina Skandali, Julia Sacher, Achim Aigner, Ralf Regenthal
Int J Clin Pharmacol Ther. Author manuscript; available in PMC 2021 Jul 5.
Published in final edited form as: Int J Clin Pharmacol Ther. 2020 Aug 1; 58(8): 426–438. doi: 10.5414/CP203705

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The Effect of Methylphenidate and Atomoxetine on Heart Rate and Systolic Blood Pressure in Young People and Adults with Attention-Deficit Hyperactivity Disorder (ADHD): Systematic Review, Meta-Analysis, and Meta-Regression

Edwin F. Liang, Samuel Z. Lim, Wilson W. Tam, Cyrus S. Ho, Melvyn W. Zhang, Roger S. McIntyre, Roger C. Ho
Int J Environ Res Public Health. 2018 Aug; 15(8): 1789. Published online 2018 Aug 20. doi: 10.3390/ijerph15081789

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Atomoxetine restores the response inhibition network in Parkinson’s disease

Charlotte L. Rae, Cristina Nombela, Patricia Vázquez Rodríguez, Zheng Ye, Laura E. Hughes, P. Simon Jones, Timothy Ham, Timothy Rittman, Ian Coyle-Gilchrist, Ralf Regenthal, Barbara J. Sahakian, Roger A. Barker, Trevor W. Robbins, James B. Rowe
Brain. 2016 Aug; 139(8): 2235–2248. Published online 2016 Jun 24. doi: 10.1093/brain/aww138

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Amplification and Suppression of Distinct Brainwide Activity Patterns by Catecholamines

Ruud L. van den Brink, Sander Nieuwenhuis, Tobias H. Donner
J Neurosci. 2018 Aug 22; 38(34): 7476–7491. doi: 10.1523/JNEUROSCI.0514-18.2018

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Atomoxetine reduces hyperactive/impulsive behaviours in neurokinin-1 receptor ‘knockout’ mice

Katharine Pillidge, Ashley J. Porter, Temis Vasili, David J. Heal, S. Clare Stanford
Pharmacol Biochem Behav. 2014 Dec; 127: 56–61. doi: 10.1016/j.pbb.2014.10.008

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Risk of Suicidal Events With Atomoxetine Compared to Stimulant Treatment: A Cohort Study

Stephan Linden, Regina Bussing, Paul Kubilis, Tobias Gerhard, Richard Segal, Jonathan J Shuster, Almut G Winterstein
Pediatrics. 2016 May; 137(5): e20153199. doi: 10.1542/peds.2015-3199

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Atomoxetine effects on attentional bias to drug-related cues in cocaine dependent individuals

Luca Passamonti, M. Luijten, H. Ziauddeen, I. T. S. Coyle-Gilchrist, T. Rittman, S. A. E. Brain, R. Regenthal, I. H. A. Franken, B. J. Sahakian, E. T. Bullmore, T. W. Robbins, K. D. Ersche
Psychopharmacology (Berl) 2017; 234(15): 2289–2297. Published online 2017 May 27. doi: 10.1007/s00213-017-4643-4

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