Full text biomedical articles

Azathioprine or 6‐mercaptopurine for induction of remission in Crohn's disease

Nilesh Chande, Cassandra M Townsend, Claire E Parker, John K MacDonald, Cochrane IBD Group
Cochrane Database Syst Rev. 2016 Oct; 2016(10): CD000545. Published online 2016 Oct 26. doi: 10.1002/14651858.CD000545.pub5


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Azathioprine and 6‐mercaptopurine for maintenance of remission in ulcerative colitis

Antje Timmer, Petrease H Patton, Nilesh Chande, John WD McDonald, John K MacDonald, Cochrane IBD Group
Cochrane Database Syst Rev. 2016 May; 2016(5): CD000478. Published online 2016 May 18. doi: 10.1002/14651858.CD000478.pub4


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Azathioprine Biotransformation in Young Patients with Inflammatory Bowel Disease: Contribution of Glutathione-S Transferase M1 and A1 Variants

Marianna Lucafò, Gabriele Stocco, Stefano Martelossi, Diego Favretto, Raffaella Franca, Noelia Malusà, Angela Lora, Matteo Bramuzzo, Samuele Naviglio, Erika Cecchin, Giuseppe Toffoli, Alessandro Ventura, Giuliana Decorti
Genes (Basel) 2019 Apr; 10(4): 277. Published online 2019 Apr 4. doi: 10.3390/genes10040277


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Azathioprine and 6‐mercaptopurine for maintenance of surgically‐induced remission in Crohn's disease

Teuta Gjuladin‐Hellon, Zipporah Iheozor‐Ejiofor, Morris Gordon, Anthony K Akobeng, Cochrane IBD Group
Cochrane Database Syst Rev. 2019 Aug; 2019(8): CD010233. Published online 2019 Aug 6. doi: 10.1002/14651858.CD010233.pub3


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Azathioprine and 6‐mercaptopurine for maintenance of surgically‐induced remission in Crohn's disease

Morris Gordon, Kelly Taylor, Anthony K Akobeng, Adrian G Thomas
Cochrane Database Syst Rev. 2014 Aug; 2014(8): CD010233. Published online 2014 Aug 1. doi: 10.1002/14651858.CD010233.pub2


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Thiopurine methyltransferase genotype and activity cannot predict outcomes of azathioprine maintenance therapy for antineutrophil cytoplasmic antibody associated vasculitis: A retrospective cohort study

Arno C. Hessels, Abraham Rutgers, Jan Stephan F. Sanders, Coen A. Stegeman
PLoS One. 2018; 13(4): e0195524. Published online 2018 Apr 9. doi: 10.1371/journal.pone.0195524


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Safety and efficacy of tocilizumab versus azathioprine in highly relapsing neuromyelitis optica spectrum disorder (TANGO): an open-label, multicentre, randomised, phase 2 trial

Chao Zhang, Meini Zhang, Wei Qiu, Hongshan Ma, Xinghu Zhang, Zilong Zhu, Chun-Sheng Yang, Dongmei Jia, Tian-Xiang Zhang, Meng Yuan, Yan Feng, Li Yang, Wenli Lu, Chunshui Yu, Jeffrey L Bennett, Fu-Dong Shi
Lancet Neurol. Author manuscript; available in PMC 2021 Mar 5.
Published in final edited form as: Lancet Neurol. 2020 May; 19(5): 391–401. doi: 10.1016/S1474-4422(20)30070-3


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Immunosuppressive treatment for proliferative lupus nephritis

David J Tunnicliffe, Suetonia C Palmer, Lorna Henderson, Philip Masson, Jonathan C Craig, Allison Tong, Davinder Singh‐Grewal, Robert S Flanc, Matthew A Roberts, Angela C Webster, Giovanni FM Strippoli, Cochrane Kidney and Transplant Group
Cochrane Database Syst Rev. 2018 Jun; 2018(6): CD002922. Published online 2018 Jun 29. doi: 10.1002/14651858.CD002922.pub4


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Pharmacogenetics of azathioprine in inflammatory bowel disease: A role for glutathione-S-transferase?

Gabriele Stocco, Marco Pelin, Raffaella Franca, Sara De Iudicibus, Eva Cuzzoni, Diego Favretto, Stefano Martelossi, Alessandro Ventura, Giuliana Decorti
World J Gastroenterol. 2014 Apr 7; 20(13): 3534–3541. Published online 2014 Apr 7. doi: 10.3748/wjg.v20.i13.3534


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Targeting pancreatic cancer metastasis by inhibition of Vav1, a driver of tumor cell invasion

Gina L. Razidlo, Christopher Magnine, Arthur C. Sletten, Rachel M. Hurley, Luciana L. Almada, Martin E. Fernandez-Zapico, Baoan Ji, Mark A. McNiven
Cancer Res. Author manuscript; available in PMC 2016 Jul 15.
Published in final edited form as: Cancer Res. 2015 Jul 15; 75(14): 2907–2915. Published online 2015 May 14. doi: 10.1158/0008-5472.CAN-14-3103


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Azathioprine Has a Deleterious Effect on the Bone Health of Mice with DSS-Induced Inflammatory Bowel Disease

Stephanie Morgan, Kirsty M. Hooper, Elspeth M. Milne, Colin Farquharson, Craig Stevens, Katherine A. Staines
Int J Mol Sci. 2019 Dec; 20(23): 6085. Published online 2019 Dec 3. doi: 10.3390/ijms20236085


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AZALEP a randomized controlled trial of azathioprine to treat leprosy nerve damage and Type 1 reactions in India: Main findings

Diana N. J. Lockwood, Joydeepa Darlong, Pitchaimani Govindharaj, Royce Kurian, Pamidipani Sundarrao, Annamma S. John
PLoS Negl Trop Dis. 2017 Mar; 11(3): e0005348. Published online 2017 Mar 30. doi: 10.1371/journal.pntd.0005348


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Autoimmune hepatitis: Standard treatment and systematic review of alternative treatments

Benedetta Terziroli Beretta-Piccoli, Giorgina Mieli-Vergani, Diego Vergani
World J Gastroenterol. 2017 Sep 7; 23(33): 6030–6048. Published online 2017 Sep 7. doi: 10.3748/wjg.v23.i33.6030


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Model-based contextualization of in vitro toxicity data quantitatively predicts in vivo drug response in patients

Christoph Thiel, Henrik Cordes, Isabel Conde, José Vicente Castell, Lars Mathias Blank, Lars Kuepfer
Arch Toxicol. 2017; 91(2): 865–883. Published online 2016 May 9. doi: 10.1007/s00204-016-1723-x


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Azathioprine does not reduce adenoma formation in a mouse model of sporadic intestinal tumorigenesis

Mattheus CB Wielenga, Jooske F van Lidth de Jeude, Sanne L Rosekrans, Alon D Levin, Monique Schukking, Geert RAM D’Haens, Jarom Heijmans, Marnix Jansen, Vanesa Muncan, Gijs R van den Brink
World J Gastroenterol. 2014 Nov 28; 20(44): 16683–16689. Published online 2014 Nov 28. doi: 10.3748/wjg.v20.i44.16683


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The adverse effect profile of oral azathioprine in pediatric atopic dermatitis, and recommendations for monitoring

Nicholas R. Fuggle, Walter Bragoli, Anjali Mahto, Mary Glover, Anna E. Martinez, Veronica A. Kinsler
J Am Acad Dermatol. 2015 Jan; 72(1): 108–114. doi: 10.1016/j.jaad.2014.08.048


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Azathioprine-induced pancytopenia with normal TPMT activity presenting with HSV oral ulcers

Caroline H Jensen, John Tiu, Jillian S Catalanotti
BMJ Case Rep. 2018; 2018: bcr2018225209. Published online 2018 Jul 11. doi: 10.1136/bcr-2018-225209


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Azathioprine: its uses in dermatology

Sonia Chavez-Alvarez, Maira Herz-Ruelas, Alejandra Villarreal-Martinez, Jorge Ocampo-Candiani, Rubicela Garza-Garza, Minerva Gomez-Flores
An Bras Dermatol. 2020 Nov-Dec; 95(6): 731–736. Published online 2020 Sep 11. doi: 10.1016/j.abd.2020.05.003


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Interventions for renal vasculitis in adults

Giles D Walters, Narelle S Willis, Tess E Cooper, Jonathan C Craig, Cochrane Kidney and Transplant Group
Cochrane Database Syst Rev. 2020 Jan; 2020(1): CD003232. Published online 2020 Jan 13. doi: 10.1002/14651858.CD003232.pub4


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Nonmelanoma skin cancer risk awareness in azathioprine‐treated myasthenia gravis patients

Iain J. McGurgan, Christopher McGuigan
Brain Behav. 2015 Oct; 5(10): e00396. Published online 2015 Sep 15. doi: 10.1002/brb3.396


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