References from scientific journals

Bupropion Hydrochloride.

Khan SR, Berendt RT, Ellison CD, Ciavarella AB, Asafu-Adjaye E, Khan MA, Faustino PJ. Khan SR, et al. Profiles Drug Subst Excip Relat Methodol. 2016;41:1-30. doi: 10.1016/bs.podrm.2015.12.001. Epub 2016 Feb 17. Profiles Drug Subst Excip Relat Methodol. 2016. PMID: 26940167 Review.

Bupropion hydrochloride is a norepinephrine-dopamine disinhibitor (NDDI) approved for the treatment of depression and smoking cessation. Bupropion is a trimethylated monocyclic phenylaminoketone second-generation antidepressant, which differs structurally from most …
Bupropion hydrochloride is a norepinephrine-dopamine disinhibitor (NDDI) approved for the treatment of depression and smoking cessati …

Naltrexone/bupropion for obesity.

[No authors listed] [No authors listed] Drug Ther Bull. 2017 Nov;55(11):126-129. doi: 10.1136/dtb.2017.11.0550. Drug Ther Bull. 2017. PMID: 29117992 Review.

Naltrexone/bupropion (Mysimba - Orexigen Therapeutics Ireland Limited) is a fixed-dose combination product for the treatment of adults who are obese or overweight with at least one weight-related comorbidity, as an adjunct to diet and lifestyle modifications. ...
Naltrexone/bupropion (Mysimba - Orexigen Therapeutics Ireland Limited) is a fixed-dose combination product for the treatment of adult …

Use of bupropion in combination with serotonin reuptake inhibitors.

Zisook S, Rush AJ, Haight BR, Clines DC, Rockett CB. Zisook S, et al. Biol Psychiatry. 2006 Feb 1;59(3):203-10. doi: 10.1016/j.biopsych.2005.06.027. Epub 2005 Sep 13. Biol Psychiatry. 2006. PMID: 16165100 Review.

This article reviews the literature on combining bupropion with SSRIs or SNRIs. We used MEDLINE to select studies that included patients diagnosed with MDD treated with any combination of bupropion and an SSRI or SNRI, either to enhance antidepressant response or to …
This article reviews the literature on combining bupropion with SSRIs or SNRIs. We used MEDLINE to select studies that included patie …

Bupropion Use During Pregnancy: A Systematic Review.

Hendrick V, Suri R, Gitlin MJ, Ortiz-Portillo E. Hendrick V, et al. Prim Care Companion CNS Disord. 2017 Sep 21;19(5):17r02160. doi: 10.4088/PCC.17r02160. Prim Care Companion CNS Disord. 2017. PMID: 28973846 Free article. Review.

The following keywords were used: bupropion, pregnancy, depression, smoking cessation, birth outcomes, miscarriage, and spontaneous abortion. ...A total of 8 studies were included in this review. RESULTS: Bupropion's use in the first trimester has been linked …
The following keywords were used: bupropion, pregnancy, depression, smoking cessation, birth outcomes, miscarriage, and spontaneous a …

Pharmacokinetic and pharmacodynamic of bupropion: integrative overview of relevant clinical and forensic aspects.

Costa R, Oliveira NG, Dinis-Oliveira RJ. Costa R, et al. Drug Metab Rev. 2019 Aug;51(3):293-313. doi: 10.1080/03602532.2019.1620763. Epub 2019 Jun 14. Drug Metab Rev. 2019. PMID: 31124380 Review.

Bupropion is a chiral, basic, highly lipophilic drug, clinically used as racemate that undergoes extensive stereoselective metabolism. Its major active metabolites, hydroxybupropion, threohydrobupropion, and erythrohydrobupropion reach higher plasma concentrations than …
Bupropion is a chiral, basic, highly lipophilic drug, clinically used as racemate that undergoes extensive stereoselective metabolism …

Bupropion for attention deficit hyperactivity disorder (ADHD) in adults.

Verbeeck W, Bekkering GE, Van den Noortgate W, Kramers C. Verbeeck W, et al. Cochrane Database Syst Rev. 2017 Oct 2;10(10):CD009504. doi: 10.1002/14651858.CD009504.pub2. Cochrane Database Syst Rev. 2017. PMID: 28965364 Free PMC article. Review.

AUTHORS' CONCLUSIONS: The findings of this review, which compared bupropion to placebo for adult ADHD, indicate a possible benefit of bupropion. ...Furthermore, we found low-quality evidence that the tolerability of bupropion is similar to that of placebo. In …
AUTHORS' CONCLUSIONS: The findings of this review, which compared bupropion to placebo for adult ADHD, indicate a possible benefit of …

Dextromethorphan/Bupropion: A Novel Oral NMDA (N-methyl-d-aspartate) Receptor Antagonist with Multimodal Activity.

Stahl SM. Stahl SM. CNS Spectr. 2019 Oct;24(5):461-466. doi: 10.1017/S1092852919001470. CNS Spectr. 2019. PMID: 31566163 Review.

The recent approval of the NMDA (N-methyl-d-aspartate) antagonist esketamine given intranasally for treatment-resistant depression has reinforced the need for agents with rapid onset with alternate mechanisms of action. Dextromethorphan/bupropion, an investigational medici …
The recent approval of the NMDA (N-methyl-d-aspartate) antagonist esketamine given intranasally for treatment-resistant depression has reinf …

Combination bupropion SR and varenicline for smoking cessation: a systematic review.

Vogeler T, McClain C, Evoy KE. Vogeler T, et al. Am J Drug Alcohol Abuse. 2016 Mar;42(2):129-39. doi: 10.3109/00952990.2015.1117480. Epub 2016 Jan 25. Am J Drug Alcohol Abuse. 2016. PMID: 26809272 Review.

Current cessation medications include nicotine replacement therapy (NRT), varenicline, and bupropion, while combination therapy primarily entails NRT with either varenicline or bupropion. ...METHODS: PubMed and Clinicaltrials.gov were searched using terms: "varenicl …
Current cessation medications include nicotine replacement therapy (NRT), varenicline, and bupropion, while combination therapy prima …

A Systematic Review of the Use of Bupropion for Attention-Deficit/Hyperactivity Disorder in Children and Adolescents.

Ng QX. Ng QX. J Child Adolesc Psychopharmacol. 2017 Mar;27(2):112-116. doi: 10.1089/cap.2016.0124. Epub 2016 Nov 4. J Child Adolesc Psychopharmacol. 2017. PMID: 27813651 Review.

RESULTS: All available open, controlled, and randomized trials demonstrated bupropion's efficacy in improving ADHD symptoms. The three head-to-head trials found that bupropion had efficacy comparable to methylphenidate (p > 0.05). However, a large double-b …
RESULTS: All available open, controlled, and randomized trials demonstrated bupropion's efficacy in improving ADHD symptoms. T …

Bupropion-Induced Spontaneous Ejaculations.

Uvais NA, Basheer S. Uvais NA, et al. Prim Care Companion CNS Disord. 2020 Jan 2;22(1):19l02453. doi: 10.4088/PCC.19l02453. Prim Care Companion CNS Disord. 2020. PMID: 31917530 Free article. No abstract available.