Can Tylenol be taken with meloxicam?


Meloxicam (Mobic) is a non-steroidal anti -inflammatory drug (NSAID) that is used alone or with other medications to treat mild to moderate pain and inflammation in arthritis . Tylenol ( acetaminophen ), which is also used to treat arthritis pain, is sometimes added to a regimen for pain that cannot be relieved by NSAIDs alone. The two drugs are generally safe to use together.

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What is the difference between meloxicam and Tylenol?

Although both meloxicam and Tylenol are used to treat pain, they differ in several ways. A dose. Meloxicam is a prescription drug taken once a day, while Tylenol is available over the counter (OTC) and dosage recommendations vary based on the strength of the product.

They also belong to different classes of drugs and work in different ways. NSAIDs relieve pain by blocking an enzyme known as cyclooxygenase or COX, which promotes the production of prostaglandins. Prostaglandins play a role in the inflammatory response in the body, so when this production is blocked, inflammation and discomfort caused by the inflammatory response is reduced.

Tylenol is a brand name of acetaminophen that belongs to a class of medications known as pain relievers. While there is still controversy about how Tylenol works in the body, it is believed that it works by also blocking the production of the COX enzyme in the central nervous system. The mechanism of action of NSAIDs and acetaminophen differs due to where they block the enzyme.

In terms of their effectiveness, meloxicam and Tylenol are equally good at relieving pain. However, Tylenol cannot reduce inflammation in the body like meloxicam.

Is it safe to take meloxicam with Tylenol?

Taking meloxicam with Tylenol is safe because there are no known drug interactions between the two drugs. However, it is important to remember to adhere to the RDA for both medications. If you exceed the dose of one or the other, dangerous side effects can occur.

Some of the side effects that can occur from taking too much Tylenol include:

  • Nausea
  • Threw up
  • Loss of appetite
  • Perspiration
  • Severe fatigue
  • Unusual bleeding or bruising
  • Pain in the upper right part of the abdomen.
  • Yellowing of the skin or eyes
  • Flu-like symptoms

When it comes to meloxicam, too much can cause some adverse health effects. They include:

  • Lack of energy
  • Drowsiness
  • Nausea
  • Threw up
  • Abdominal pain
  • Bloody, black, or tarry stools
  • Vomiting blood or coffee grounds
  • Difficulty breathing
  • Seizures
  • Eat

Too much medicine can lead to liver toxicity. In the case of Tylenol, the liver is designed to break down the drug into separate parts. Parts that are used for pain relief remain within the body, while unnecessary parts, such as the toxic byproduct of Tylenol's metabolism, N-acetyl-p-benzoquinone imine, are excreted in the urine. If you take too much Tylenol, this toxic byproduct produced in the liver builds up because the liver cannot remove it fast enough, leading to liver damage.

When it comes to meloxicam, the cause of liver toxicity is unclear, but in very rare cases it can still occur.

NSAID warnings

When taken for pain, NSAIDs like meloxicam are usually for short-term use, for example, no more than 10 days in a row. There are times when your doctor may prescribe NSAIDs for a longer period of time, but these are special circumstances and your doctor will inform you of this.

Taking NSAIDs can increase your risk of heart attacks and strokes. The risk is higher when the drug is taken in higher doses and for a long period of time, but it can also increase during the first few weeks of taking the drug. Although people who already have heart disease are more likely to develop these side effects, they can occur even in people who do not have a history of heart disease.

NSAIDs have also been shown to increase the risk of stomach and intestinal side effects, such as stomach ulcers or bleeding. The risk of developing these side effects is higher in older people, people with a history of stomach ulcers, people who take blood thinners, those who drink alcohol on a daily basis, and those who take more than one prescription or over-the-counter NSAIDs.

When taking NSAIDs, you should only take one type at a time. Taking two types of NSAIDs at the same time can increase the risk of side effects such as liver toxicity and kidney failure.

Serious side effects

In some cases, serious side effects can occur when taking meloxicam. Your healthcare professional should immediately eliminate the following symptoms:

  • Gastrointestinal problems such as black stools, bloody or cloudy urine, severe abdominal pain, vomiting that resembles coffee grounds, changes in urination, unusual weight gain, or jaundice.
  • Headache problems such as blurred vision, ringing in the ears, sensitivity to light, excruciating headache, trouble speaking or thinking, or imbalance.
  • Fluid retention, which manifests as swelling of the mouth, face, lips, tongue, ankles, feet, legs, or hands.
  • Signs of an allergic reaction such as a rash or hives, red and scaly skin, itching, or trouble breathing.
  • Bruising or bleeding that cannot be explained
  • Breast problems such as pain, fast or racing heartbeat, and fast heartbeat.
  • Flu-like symptoms with acute fatigue
  • Excruciating back pain

Acetaminophen warnings

Taking too much acetaminophen can cause serious liver damage, especially when taken with other medications that can damage the liver. Drinking alcohol while taking acetaminophen also increases the risk of liver damage.

Signs and symptoms of an allergic reaction to Tylenol include skin redness, blisters, and rashes. Tylenol users should not mix it with other medications that contain acetaminophen and should not be taken more than 10 days for pain relief and three days for fever. Do not exceed 3 grams of paracetamol per day (maximum recommended daily intake).

Before taking Tylenol, tell your doctor or pharmacist if you have liver disease or if you are taking warfarin (a blood-thinning medicine). Children and teens should only take this medicine if they are not recovering from symptoms of chickenpox or the flu.


Symptoms of liver toxicity caused by a Tylenol overdose include jaundice or yellowing of the skin and whites of the eyes, confusion, or liver failure . In some severe cases, liver damage can lead to death. Other symptoms that may be present if your liver is damaged by overuse of acetaminophen:

  • Abdominal pain
  • Nausea and vomiting
  • Fatigue
  • Excessive sweating
  • Dark urine and stools
  • Pale skin

If you experience any of these symptoms and think you have taken too much Tylenol, seek medical attention immediately.

Get the word of drug information

Pain relief is vital when it comes to living as normally as possible with a chronic medical condition such as arthritis. Although it is common to take meloxicam and Tylenol together, always check with your doctor before starting any new medication to make sure it is safe for you, given your health and medication history. When used correctly, pain relievers can help you get back to life as happy and healthy as possible.

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