Causes and risk factors Hypercalemia


Hyperkalemia is a medical term for blood potassium levels that are Too high. Potassium is a chemical element that is necessary for life.This is especially important for the normal functioning of organ organ organs that are based on the transfer of the electric signaling heart, muscles and nerves.

There are many factors and diseases that can lead to hyperamemias , including kidney disease, heart failure , diabetes and certain medications. In adults, the normal blood level of potassium varies from 3.6 to 5.2 mec / L. Potassium levels, which are too low (hypokalemia), or too high, can be dangerous for the problems of life.

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General reasons

There are numerous potential causes of hyperkalemia ,But they can be broken into three main categories.

Reducing the potassium selection

Since the maintenance of a normal level of potassium is crucial,Our kidneys have effective mechanisms to prepare potassium to prevent our levels also from going down to highlight the excess potassium in the urine to avoid too many levels.

however, with acute and acute renal failure or chronic kidney disease , kidney capacity to assign potassium often deteriorates,and hyperkemia can support the failure

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Extended vacation potassium of the cells

, because the concentration of potassium within its subodes cells is approximately 30 times higher,Something in your blood, all that causes a greater potassium distinction from the inside of the cells to outer cells can produce hyperklemia.

When your body contains too much acid, called acidosis, for example, with diabetic cetosis , potassium movements of your cells and can cause significant and potentially deadly hyperkalemia . .

The damage to the fabric can also create a potassium displacement from the cells of the outer cells, simply by the traumatic destruction of the cell membranes.Hyperkalemia of tissue damage can occur with any type of serious injury, burns, surgery, rapid destruction of tumor cells, hemolytic anemia or rlydomolysis the destruction of muscle cells,That Canoscur thermal stroke or with alcohol or drugs reported the stupor.

Other potential causes of high potassium release from your body cells include:

  • insulin deficiency, which leads to hyperglycemia (too much blood glucose),what can occur with uncontrolled pancake or diabetes
  • insulin deficiency as a result of the publication, especially in people who are in dialysis
  • insulin deficiency,of the adoption of somatostatin or capotatin (octreotide), hormones, which inhibit growth hormones
  • tumor of lysis syndrome, which can occur if it has lymphoma or leukemia,as well as chemotherapy or radiation therapy
  • Betlocators
  • blood transfusions

excess potassium

If the kidney usually runs, it is quite difficult to develop a hyperkalemia,Just by awakening too potassium in your diet.However, blood potassium levels can be carried out too high if it takes a large number of potash additives, especially if it also has some degree of kidney disease, if you are taking medications that inhibit the excretion of potassium,As mentioned earlier.


Two hereditary disorders that can cause hyperkalemia. Genetic tests can be diagnosed.

pseudohipaldosteroneism Type 1

pseudogapaldosteroneism Type 1 (PHA1) It makes it difficult for your The body to regulate sodium, which occurs mainly in its kidneys.There are two types of PHA1:

  1. Autosomal Pha1 Dominant, which is mild and generally improved in childhood.
  2. Recessive PHA1, which is heavier better.

This last disorder can lead to hyperkalemia, since the high amounts of sodium , cause low levels of sodium and high potassium levels, stand out in its urine.In fact, hyperkalemia is considered one of the main characteristics of this disorder.

pseudohipaldosteroneism of type 1 is caused by mutations in one of the four genes that affect the sodium regulation.These genes include the NR3C2 (gene that causes the autosomal dominant PHA1), SCN1A, SCNN1B or SCNN1G, which causes Recessive AutoSomal PHA1. This condition affects only about 1 newborn babies. . Syndrome, this is another hereditary condition that causes hyperkalemia.This disorder complicates its body to regulate both sodium and potassium, which leads to high blood pressure and hyperkalemia, the renal function of Yernenemal.Hypercalemia tends to occur first, while high blood pressure develops later.

PHA2 is caused by mutations in Hun WNK1, WNK4, CUL3 or KLHL3 all of them helps regulate blood pressure.It is also a rare disorder, but it is not known with which the PHA2 is produced.


CAREGARIVE heart failure is considered one of the causes of hyperkalemia, as some of the medications that often lead to people with heart failure,Including diuretics, ECE inhibitors and beta. Blockers Because of this, if you have stagnant heart failure, and you take any of these vital medications, you may need to limit the amount of potassium to your diet to help reduce The risk of developing hyperkalemia.It is also likely that your health provider has renewed the level of potassium in your blood and make sure you are in a minimum amount of drug types that cause an increase in the level of potassium.

Lifestyle risk factors

If you have diabetes, for many reasons, for which it is important to control your diseases, it is the risk of developing hyperkalemia, which can lead to death,If it becomes serious. When your diabetes is poorly controlled or uncontrollable, too much glucose ends in the blood. This creative insulin deficiency, which can lead to hyperkalemia and other problems of threatening life.Be sure to work with your health care provider to find a treatment program , which works for you to control blood glucose so that it can reduce your risks of serious and potentially dangerous effects for life .

Frequently Asked Questions

  • The increase in potassium causes obvious symptoms, by What hyperkalemia is often not diagnosed until it appears during the tests for some other conditions.However, the symptoms of hyperkalemia that can be easy to incorporate for other health states are:

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  • , when there is too much hydrophone in the body and or sodium, it can interfere with electrical signals in myocardium, which is a thick layer of muscles in the middle of the heart. The result can be irregular heart rhythms .

  • Usually, only if you are a risk of hyperkalemia.In this case, the limitation or elimination of certain products can help prevent its development,Including:


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