Cystic Fibrosis (CF): Overview and More

The cystic fibrosis transmembrane conductance regulator (CFTR) is a protein that regulates the movement of chloride (a component of salt) and water within cells. In cystic fibrosis, the CFTR protein is defective, because chloride is retained within cells and water cannot hydrate the outer surfaces of cells. As a result, thick mucus builds up in the lungs and other organs .

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