Doxycycline: Uses, Side Effects, Dosages, and Precautions


Vibramycin is one of many brands of doxycycline, a widely used antibiotic that is prescribed to treat a wide range of bacterial infections, from acne to urinary tract infections (UTIs). It belongs to a class of antibiotics called tetracyclines, which work by killing the bacteria that caused the infection or by preventing them from growing.

This drug comes in a variety of forms, making it a versatile option:

  • Suspension powder (mix with water)
  • Tablets
  • Capsules
  • Delayed-release tablets and capsules
  • Injections
  • Syrup
  • In addition to being available as vibramycin and as generics, doxycycline is marketed in the United States under other brand names such as Doryx, Monodox, and Oracea.


The Food and Drug Administration (FDA) has approved doxycycline for the treatment of a wide range of infections:

  • Acne
  • Actinomycosis
  • Acute intestinal amebiasis
  • Anger
  • Clostridium
  • Gram-negative infections
  • Listeriosis
  • Malaria prevention
  • Mycoplasma pneumonia
  • Eye infections
  • Periodontitis
  • Chronic fever
  • Respiratory tract infections
  • Rickettsial infections
  • Rosacea
  • Sexually transmitted infections
  • Skin infections
  • Vincent infection
  • Zoonotic infections

Use not indicated on the label

Doxycycline is also used off-label. It can be prescribed for treatment:

  • Anaplasmosis
  • Ehrlichiosis
  • Bite infections
  • Cellulitis
  • Chronic obstructive pulmonary disease, exacerbations
  • Epididymitis
  • Purulent hydradenitis
  • Lyme's desease
  • Malara, acute treatment
  • Otitis media
  • Pelvic inflammatory disease
  • Pleurodesis
  • Proctitis
  • Joint prosthesis infection
  • Surgical prevention of uterine emptying.

Before drinking

Your healthcare provider will likely prescribe doxycycline if tests show that you have a bacterial infection, or sometimes if they suspect you have an infection due to symptoms such as fever, sweating, and chills.

Share your medical history with them, as well as any current health problems, allergies, or other medications or supplements you are taking. It will be especially important to alert your doctor if you have ever had a bad reaction to a tetracycline antibiotic.

[Standard Disclaimer: Talk to your doctor about all medications, supplements, and vitamins you are currently taking. While some medications carry little risk of interactions, others may directly contraindicate their use or prompt careful consideration of whether the benefits of treatment outweigh the disadvantages for you.]

Precautions and contraindications.

Doxycycline is contraindicated in anyone who has had an allergic reaction to a tetracycline antibiotic in the past. If you know this to be the case, inform your doctor so that he can prescribe a more suitable medication.

Be aware that there are several chronic diseases and conditions that can interfere with taking doxycycline or cause it to be used with caution. Tell your doctor if you have yeast infections.

Elderly A special dose of doxycycline may be required, usually relatively small doses, the effectiveness of which can be carefully adjusted. Doxycycline should not be taken by pregnant or lactating women, or by children under 8 years of age.

Doxycycline is not recommended if you are also taking soriatan (acitretin), an oral retinoid commonly used to treat psoriasis.


There are many forms and doses of doxycycline for adults. What your healthcare provider chooses will depend on your size, why you are taking the medication, and possibly your preferences:

  • Capsules of 50, 75 and 100 milligrams (mg)
  • Delayed-release capsules 40 mg
  • Intravenous solutions 100 mg
  • Oral solutions 25 mg per 5 milliliters (ml)
  • 20, 50, 75, 100 and 150 mg tablets.
  • 50, 75, 80, 100, 150 and 200 mg delayed-release tablets and capsules.

The adult dose is 100 mg to 200 mg per day, divided into two doses or once a day.

Doxycycline is generally not prescribed for children younger than 8 years old. In cases where the risks outweigh the benefits, the typical dose of doxycycline depends on the age and weight of the child:

  • For children over 8 years of age who weigh more than 45 kilograms (kg) – about 99 pounds: 100 mg twice a day on the first day, then 50 mg or 100 mg once or twice a day.
  • For children older than 8 years who weigh less than 45 kg, the typical dose is 4.4 mg / kg / day, divided into two doses on the first day, then 2.2 mg / kg / day in one or two doses. every day thereafter. ..
  • For children under 8 years of age, the doctor will calculate the individual dose of Vibramycin.

[Standard Disclaimer: All dosages listed are provided by the drug manufacturer. Check your prescription and talk to your doctor to make sure you are taking the correct dose].


Older people may need special doses of doxycycline.

How to take and store

There are a few things to keep in mind while taking doxycycline or giving it to your child to make sure the medicine is safe and effective.

  • Doxycycline can upset your stomach. This is not a cause for concern, but can be avoided by taking the medicine with food or drink.
  • If a delayed-release tablet or capsule is prescribed, swallow it whole; do not crush or chew it.
  • The delayed-release capsules can be opened and sprinkled with food.
  • Shake liquids and suspensions before taking doxycycline or before giving it to a child.
  • If you miss a dose, take it as soon as you realize you missed it, unless it is time for your next scheduled dose. In this case, do not worry about the missed dose and choose the next dose on your usual schedule. Do not take a double dose of doxycycline.
  • Store doxycycline in its original container to avoid confusion with other medications in your home. It should be kept out of the reach of children, away from moisture, heat or direct light. A bathroom that can get foggy is not ideal.
  • Do not stop taking doxycycline without first talking to your healthcare professional.

Side effects

Vibramycin is known to cause several side effects.


Most are mild and rarely cause concern, but you should still report them to your doctor.

  • Stomach ache
  • Diarrhea
  • Nausea
  • Loss of appetite
  • Clay-colored stools
  • Sensitivity to sunlight
  • Tooth discoloration in children
  • Yeast infections, including oral thrush
  • Skin discoloration

Severe form

Call your doctor immediately if you experience any serious symptoms while taking Vibramycin, such as:

  • Temperature jump
  • Rash
  • Swallowing problems
  • Feeling like your throat is closing
  • Urticaria
  • Joint pain
  • Yellow skin or eyes (jaundice)
  • Dizziness
  • Cardiopalmus
  • Confusion

Warnings and interactions

Taking medications that can interact with doxycycline while taking doxycycline are not recommended, such as:

  • Amoxicillin
  • Ampicillin
  • Ettretinate
  • Isotretinoin
  • Methotrexate
  • Penicillin of any kind

You are at increased risk of impaired absorption of one or both drugs if you are taking any of the following drugs or substances while taking Vibramycin:

  • Alcohol
  • Aluminum (all shapes)
  • Aminolevulinic acid
  • Bismuth subsalicylate
  • Calcium
  • Dihydroxyaluminum aminoacetate or sodium carbonate
  • Iron
  • Magaldrat
  • Magnesium (all forms)
  • Rifampicin
  • Rifapentine
  • Tobacco
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