Clinical Trials

Response of Patients on Surveillance for Prostate Cancer to Dutasteride

Condition:   Prostate Cancer
Intervention:   Drug: Dutasteride
Sponsors:   Sunnybrook Health Sciences Centre;   Toronto Sunnybrook Regional Cancer Centre
Completed

Fri, 03 Feb 2012 12:00:00 EST

Study Assessing The Efficacy And Safety Of Avodart (Dutasteride) At Improving Urinary Symptoms In Men With Prostate Cancer Who Are Undergoing Seed Implantation

Condition:   Prostate Cancer
Interventions:   Drug: avodart;   Drug: Placebo
Sponsors:   Bay State Clinical Trials, Inc.;   GlaxoSmithKline
Completed

Wed, 10 Dec 2008 12:00:00 EST

ARTS - AVODART After Radical Therapy For Prostate Cancer Study

Conditions:   Neoplasms, Prostate;   Prostate Cancer After a Radical Treatment
Interventions:   Drug: Avodart;   Other: placebo
Sponsor:   GlaxoSmithKline
Completed

Wed, 14 Nov 2007 12:00:00 EST

MRI and Magnetic Resonance Spectroscopy Imaging in Patients Receiving Dutasteride for Benign Prostatic Hypertrophy and Low-Risk Prostate Cancer

Conditions:   Nonmalignant Neoplasm;   Prostate Cancer
Intervention:   Drug: dutasteride
Sponsor:   University of California, San Francisco
Completed

Mon, 30 Jun 2008 12:00:00 EDT

Dutasteride Treatment for Reducing Heavy Drinking in AUD: Predictors of Efficacy

Condition:   Alcohol Use Disorder
Interventions:   Drug: Dutasteride Capsules;   Drug: Placebo Capsules
Sponsors:   UConn Health;   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting

Mon, 23 Sep 2019 12:00:00 EDT

AVODART® Alopecia Post-marketing Surveillance (PMS)

Condition:   Alopecia
Intervention:   Drug: Dutasteride
Sponsor:   GlaxoSmithKline
Completed

Fri, 30 Oct 2009 12:00:00 EDT

Effect of Dutasteride on Bladder Wall Hypertrophy in Patients With Benign Prostatic Obstruction

Condition:   Benign Prostatic Hyperplasia
Intervention:   Drug: Dutasteride
Sponsors:   Samsung Medical Center;   GlaxoSmithKline
Completed

Fri, 23 Jan 2009 12:00:00 EST

Pharmacokinetic Study of Single Dose Dutasteride in Healthy Subjects

Conditions:   Alcohol Related Disorders;   Alcoholism;   Alcohol Abuse
Intervention:   Drug: Dutasteride
Sponsors:   UConn Health;   National Institutes of Health (NIH);   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Completed

Thu, 04 Dec 2008 12:00:00 EST

Role of Dutasteride in Patients Undergoing 3D Mapping Biopsy in Early Stage Prostate Cancer

Condition:   Prostate Cancer
Interventions:   Drug: Dutasteride;   Other: Placebo
Sponsors:   University of Colorado, Denver;   GlaxoSmithKline
Terminated

Mon, 28 Sep 2009 12:00:00 EDT

Dutasteride for the Reduction of Alcohol Use in Male Drinkers

Conditions:   Alcoholism;   Alcohol Abuse;   Alcohol Dependence
Interventions:   Drug: Dutasteride;   Drug: Placebo
Sponsors:   UConn Health;   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Completed

Fri, 17 Dec 2010 12:00:00 EST

Dutasteride After Failure of Finasteride In the Management of Symptomatic Prostatic Enlargement/Hypertrophy (BPE/H)

Condition:   Benign Prostatic Hypertrophy
Intervention:   Drug: Dutasteride
Sponsor:   North Florida/South Georgia Veterans Health System
Completed

Fri, 29 Sep 2006 12:00:00 EDT

Dutasteride to Treat Spinal and Bulbar Muscular Atrophy (SBMA)

Conditions:   Kennedy's Disease;   Spinal and Bulbar Muscular Atrophy
Interventions:   Drug: Dutasteride;   Drug: Placebo
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Completed

Thu, 16 Mar 2006 12:00:00 EST

AVODART(Dutasteride) Post-marketing Surveillance(PMS)

Conditions:   Benign Prostatic Hyperplasia;   Prostatic Hyperplasia
Intervention:   Drug: Dutasteride
Sponsor:   GlaxoSmithKline
Completed

Fri, 18 Feb 2011 12:00:00 EST

Bioequivalence - Duodart Against Avodart & Omnic

Condition:   Prostatic Hyperplasia
Interventions:   Drug: dutasteride/tamsulosin;   Drug: dutasteride;   Drug: tamsulosin
Sponsor:   GlaxoSmithKline
Completed

Mon, 06 Aug 2012 12:00:00 EDT

Effect of Dutasteride on Androgen-Response Gene Expression in Patients With Advanced Prostate Cancer

Condition:   Prostate Cancer
Interventions:   Drug: Dutasteride;   Drug: Placebo
Sponsors:   NorthShore University HealthSystem;   University of Chicago;   Northwestern University
Completed

Tue, 29 Apr 2008 12:00:00 EDT

Dutasteride Treatment for the Reduction of Heavy Drinking in Men

Conditions:   Alcoholism;   Alcohol Abuse;   Alcohol Dependence
Interventions:   Drug: Dutasteride;   Drug: sugar pill
Sponsors:   UConn Health;   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Completed

Tue, 01 Jan 2013 12:00:00 EST

Bioequivalence Study of Dutasteride Capsules in Healthy Japanese Male Subjects

Condition:   Prostatic Hyperplasia
Interventions:   Drug: Dutasteride-Test product;   Drug: Dutasteride-Reference product
Sponsor:   GlaxoSmithKline
Completed

Mon, 19 Oct 2015 12:00:00 EDT

Ketoconazole, Hydrocortisone and Dutasteride in Asymptomatic Hormone Refractory Prostate Cancer

Condition:   Prostate Cancer
Intervention:   Drug: Ketoconazole, Hydrocortisone and Dutasteride
Sponsors:   Beth Israel Deaconess Medical Center;   Massachusetts General Hospital;   Dana-Farber Cancer Institute;   Sunnybrook Health Sciences Centre;   Oregon Health and Science University;   M.D. Anderson Cancer Center;   Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Completed

Wed, 07 May 2008 12:00:00 EDT

A Study To Assess The Efficacy And Safety Of Dutasteride 0.5mg Once Daily For 6 Months In The Treatment Of Male Subjects With Androgenetic Alopecia

Condition:   Alopecia
Intervention:   Drug: Dutasteride 0.5mg oral tablets
Sponsor:   GlaxoSmithKline
Completed

Wed, 28 Feb 2007 12:00:00 EST

A Long-term Study to Determine Safety and Efficacy of Dutasteride in Male Subjects With Androgenetic Alopecia

Condition:   Alopecia
Intervention:   Drug: Dutasteride 0.5 mg
Sponsor:   GlaxoSmithKline
Completed

Mon, 15 Apr 2013 12:00:00 EDT

Assessment Of Dutasteride (AVODART) In Extending The Time To Progression Of Low-Risk, Localized Prostate Cancer In Men

Condition:   Neoplasms, Prostate
Interventions:   Drug: Dutasteride;   Drug: Matching placebo
Sponsor:   GlaxoSmithKline
Completed

Tue, 15 Aug 2006 12:00:00 EDT


Role of Dutasteride in Treatment of Chronic Prostatitis

Conditions:   Dutasteride;   Category IIIB Chronic Prostatitis
Interventions:   Drug: Dutasteride 0.5 mg;   Drug: Placebo
Sponsor:   Ain Shams University
Completed

Tue, 16 Feb 2021 12:00:00 EST

Sexual Function in Men Receiving Dutasteride for Androgenetic Alopecia

Condition:   Alopecia
Interventions:   Drug: Dutasteride;   Drug: Placebo
Sponsors:   Stiefel, a GSK Company;   GlaxoSmithKline
Completed

Wed, 18 Dec 2013 12:00:00 EST

Safety and Efficacy of 0.5mg Dutasteride and 0.4mg Tamsulosin Combination Once Daily for Six Months for Benign Prostatic Hyperplasia

Condition:   Prostatic Hyperplasia
Intervention:   Drug: Dutasteride/Tamsulosin
Sponsor:   GlaxoSmithKline
Terminated

Tue, 28 Aug 2012 12:00:00 EDT

Extension Study of GI198745 to Treat Benign Prostatic Hyperplasia

Conditions:   Benign Prostatic Hyperplasia;   Prostatic Hyperplasia
Interventions:   Drug: GI198745 0.05mg;   Drug: GI198745 0.5mg;   Drug: GI198745 2.5mg
Sponsor:   GlaxoSmithKline
Completed

Mon, 31 Aug 2009 12:00:00 EDT

Benign Prostatic Hyperplasia Trial With Dutasteride And Tamsulosin Combination Treatment

Condition:   Prostatic Hyperplasia
Interventions:   Drug: dutasteride 0.5mg once daily for 4 years;   Drug: tamsulosin 0.4mg once daily for 4 years
Sponsor:   GlaxoSmithKline
Completed

Thu, 26 Aug 2004 12:00:00 EDT

Comparing 0.5 mg Dutasteride vs Placebo Daily in Men Receiving Androgen Ablation Therapy for Prostate Cancer

Condition:   Prostate Cancer
Intervention:   Drug: Dutasteride
Sponsors:   Canadian Urology Research Consortium;   GlaxoSmithKline
Completed

Tue, 06 Nov 2007 12:00:00 EST

Enzalutamide & Dutasteride as 1st Line Treatment for Patients =/> 65 Years Old With Prostate Cancer.

Condition:   Prostate Cancer
Intervention:   Drug: Enzalutamide and Dutasteride
Sponsor:   University of Rochester
Active, not recruiting

Mon, 11 Aug 2014 12:00:00 EDT

STA-9090 in Castration-Resistant Prostate Cancer With Assessment of Androgen Receptor Pathway Signaling

Condition:   Adenocarcinoma of the Prostate
Interventions:   Drug: STA9090;   Drug: STA9090 with Dutasteride
Sponsor:   Toni Choueiri, MD
Withdrawn

Tue, 07 Jun 2011 12:00:00 EDT

Study to Compare the Bioavailability of Dutasteride Novel Formulation Form to the Soft Gel Capsule Form in Healthy Male Subjects

Condition:   Prostatic Hyperplasia
Intervention:   Drug: dutasteride
Sponsor:   GlaxoSmithKline
Completed

Mon, 16 Apr 2012 12:00:00 EDT

Effect of Dutasteride on HIF-1alpha and VEGF in the Prostate

Condition:   Benign Prostatic Hyperplasia
Intervention:   Drug: dutasteride
Sponsors:   Seoul National University Hospital;   The Korean Urological Association;   GlaxoSmithKline
Completed

Tue, 14 Apr 2009 12:00:00 EDT

Efficacy and Toxicity of Bicalutamide and Dutasteride vs. Standard Care for Prostate Cytoreduction for Brachytherapy

Conditions:   Prostate Cancer;   Erectile Dysfunction;   Lower Urinary Tract Symptoms
Interventions:   Drug: administration of a LHRH agonist and Bicalutamide;   Drug: administration of Bicalutamide, Dutasteride and Tamoxifen
Sponsors:   CHU de Quebec-Universite Laval;   GlaxoSmithKline
Unknown status

Fri, 20 Mar 2009 12:00:00 EDT

Abiraterone Acetate Combined With Dutasteride for Metastatic Castrate Resistant Prostate Cancer

Condition:   Prostate Cancer
Interventions:   Drug: Abiraterone acetate;   Drug: Dutasteride;   Drug: Prednisone
Sponsor:   Mary-Ellen Taplin, MD
Completed

Wed, 13 Jul 2011 12:00:00 EDT

Safety and Pharmacokinetic Characteristics of DKF-313

Conditions:   Benign Prostate Hyperplasia;   Healthy
Interventions:   Drug: DKF-313;   Drug: AVODART;   Drug: CIALIS
Sponsor:   Dongkook Pharmaceutical Co., Ltd.
Completed

Mon, 02 Feb 2015 12:00:00 EST

Dutasteride 0.5mg For The Treatment Of Chinese Patients With Benign Prostatic Hyperplasia (BPH)

Conditions:   Benign Prostatic Hyperplasia;   Prostatic Hyperplasia
Interventions:   Drug: Dutasteride 0.5mg capsule;   Drug: Dutasteride matched placebo
Sponsor:   GlaxoSmithKline
Completed

Tue, 11 Sep 2007 12:00:00 EDT

Dutasteride (GI198745) In Benign Prostatic Hyperplasia Subjects

Condition:   Prostatic Hyperplasia
Interventions:   Drug: Dutasteride;   Drug: Placebo
Sponsor:   GlaxoSmithKline
Completed

Tue, 29 Aug 2006 12:00:00 EDT

A Clinical Trial Comparing Laser TURP With and Without Dutasteride.

Condition:   Benign Prostatic Hyperplasia
Interventions:   Drug: Dutasteride (Avodart);   Drug: Placebo
Sponsors:   Northwestern University;   GlaxoSmithKline
Terminated

Tue, 06 Feb 2007 12:00:00 EST

To Evaluate the Pharmacokinetics and Safety of AD-208

Condition:   Androgenetic Alopecia
Interventions:   Drug: AD-208;   Drug: Avodart Soft Capsule 0.5mg
Sponsor:   Addpharma Inc.
Completed

Thu, 02 Jan 2020 12:00:00 EST

Pharmacokinetics and Safety/Tolerability of YY-201 in Comparison to Dutasteride and Tadalafil

Condition:   Benign Prostatic Hyperplasia
Interventions:   Drug: Dutasteride 0.5 mg;   Drug: Tadalafil 5 mg;   Drug: YY-201
Sponsor:   Yuyu Pharma, Inc.
Completed

Mon, 07 Aug 2017 12:00:00 EDT

Effects of Testosterone Plus Dutasteride or Placebo on Muscle Strength, Body Composition and Metabolism in Transmen

Conditions:   Transgenderism;   Hypogonadism
Interventions:   Drug: dutasteride 5 mg/day;   Drug: Testosterone Undecanoate
Sponsor:   Unita Complessa di Ostetricia e Ginecologia
Completed

Fri, 11 Sep 2020 12:00:00 EDT

Molecular Mechanisms of Dutasteride and Dietary Interventions to Prevent Prostate Cancer and Reduce Its Progression

Conditions:   Prostatic Neoplasms;   Low Grade Prostate Cancer
Interventions:   Other: Dietary intervention first;   Drug: Drug (Dutasteride) intervention first
Sponsors:   CHU de Quebec-Universite Laval;   Prostate Cancer Canada
Active, not recruiting

Tue, 31 Jul 2012 12:00:00 EDT

Efficacy Study for Use of Dutasteride (Avodart) With Testosterone Replacement

Condition:   Hypogonadism
Interventions:   Drug: dutasteride;   Drug: placebo
Sponsors:   The Miriam Hospital;   GlaxoSmithKline
Completed

Tue, 16 Sep 2008 12:00:00 EDT

Bioequivalence Study of Dutasteride Five 0.1 mg and One 0.5 mg Soft Gelatin Capsules in Healthy Male Volunteers

Condition:   Alopecia
Interventions:   Drug: GI198745 0.1 mg;   Drug: GI198745 0.5 mg
Sponsor:   GlaxoSmithKline
Completed

Tue, 27 Aug 2013 12:00:00 EDT

TRADE-Testosterone Replacement and Dutasteride Effectiveness

Conditions:   Hypogonadism;   Benign Prostatic Hyperplasia
Interventions:   Drug: Dutasteride;   Drug: Testosterone gel;   Drug: Placebo dutasteride
Sponsors:   University of Washington;   GlaxoSmithKline;   Seattle Institute for Biomedical and Clinical Research;   VA Office of Research and Development;   Solvay Pharmaceuticals
Completed

Mon, 19 Sep 2005 12:00:00 EDT

A Study to Determine the Bioavailability of a Fixed Dose Combination Product of Dutasteride (0.5mg) and Tamsulosin Hydrochloride (0.2mg) Relative to Co-administration of the Individual Components in Healthy Male Subjects of North East Asian and Non-Asian Ancestry.

Condition:   Prostatic Hyperplasia
Intervention:   Drug: Dutasteride (0.5mg); Tamsulosin hydrochloride (0.2mg); fixed dose combination product of duatsteride (0.5mg) and tamsulosin hydrochloride (0.2mg)
Sponsor:   GlaxoSmithKline
Completed

Mon, 06 Dec 2010 12:00:00 EST

Prevention of Prostate Cancer With Dutasteride in Case of High Grade PIN Neoplasia

Condition:   Prostate Cancer
Interventions:   Drug: dutasteride;   Procedure: prostate biopsy
Sponsor:   Kaunas University of Medicine
Completed

Tue, 28 Oct 2008 12:00:00 EDT

Bioavailability Study of Fixed Dose Combination (FDC) Dutasteride and Tamsulosin Hydrochloride (HCl) Relative to One Dutasteride and One Tamsulosin HCl Tablet in Healthy Male Subjects

Condition:   Prostatic Hyperplasia
Interventions:   Drug: FDC capsule of dutasteride and tamsulosin;   Drug: Dutasteride soft gelatine capsule and tamsulosin HCl oral disintegrating tablet
Sponsor:   GlaxoSmithKline
Completed

Mon, 27 Jul 2015 12:00:00 EDT

Bioavailability of Two Combination Products of Dutasteride (0.5mg) and Tamsulosin Hydrochloride (0.2mg) in Asian Males.

Condition:   Prostatic Hyperplasia
Interventions:   Drug: Dutasteride (0.5mg);   Drug: FDC product of dutasteride (0.5mg) and tamsulosin HCl (0.2mg);   Drug: Harnal D Tablets and Harnal Capsules (both comprising 0.2 mg tamsulosin HCl)
Sponsor:   GlaxoSmithKline
Completed

Wed, 16 Nov 2011 12:00:00 EST

Bioequivalence Study of the Second Generation Dutasteride and Tamsulosin Hydrochloride (HCL) Combination Capsule in Fasted State

Condition:   Urologic Diseases
Interventions:   Drug: Commercially available combination of dutasteride 0.5 mg and tamsulosin HCL 0.4 mg;   Drug: Second generation dutasteride 0.5 mg and tamsulosin HCL 0.4 mg combination capsule
Sponsor:   GlaxoSmithKline
Completed

Mon, 03 Feb 2014 12:00:00 EST

A Study to Determine the Improvement of the Symptoms of Benign Prostatic Hyperplasia (BPH) When Switching Subjects From Proscar to Avodart

Condition:   Benign Prostatic Hyperplasia
Intervention:   Drug: Dutasteride
Sponsor:   Urologic Consultants of Southeastern PA
Unknown status

Thu, 05 Jun 2008 12:00:00 EDT

Oral Androgens in Man-3 (ORAL T-3) Pharmacokinetics of Oral Testosterone

Conditions:   Contraception;   Hypogonadism
Interventions:   Drug: Oral Testosterone;   Drug: Leuprolide (Lupron);   Drug: Dutasteride
Sponsors:   University of Washington;   GlaxoSmithKline;   National Institutes of Health (NIH);   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Completed

Mon, 12 Sep 2005 12:00:00 EDT

Bioequivalence Study of the Second Generation Dutasteride and Tamsulosin HCl Combination Capsule in Fed State

Condition:   Urologic Diseases
Interventions:   Drug: Commercially available combination of dutasteride 0.5 mg and tamsulosin HCL 0.4 mg;   Drug: Second generation dutasteride 0.5 mg and tamsulosin HCL 0.4 mg combination capsule
Sponsor:   GlaxoSmithKline
Completed

Mon, 10 Feb 2014 12:00:00 EST

Dutasteride With Tolterodine ER or Placebo to Treat Lower Urinary Tract Symptoms (LUTS)

Condition:   Benign Prostatic Hyperplasia (BPH)
Interventions:   Drug: Tolterodine ER 4mg;   Drug: Placebo;   Drug: Pre-randomization Dutasteride
Sponsors:   Siami, Paul F., M.D.;   GlaxoSmithKline;   Pfizer
Completed

Tue, 14 Jul 2009 12:00:00 EDT

Exogenous Testosterone Plus Dutasteride for the Treatment of Castrate Metastatic Prostate Cancer

Conditions:   Prostate Cancer;   Castration-resistant, Metastatic
Intervention:   Other: testosterone (AndroGel®) with the 5α-reductase inhibitor dutasteride
Sponsors:   Memorial Sloan Kettering Cancer Center;   GlaxoSmithKline;   University of Washington
Completed

Mon, 02 Mar 2009 12:00:00 EST

Finasteride, Dutasteride and Insulin Action

Condition:   Healthy Volunteers
Interventions:   Drug: Finasteride;   Drug: Dutasteride
Sponsor:   University of Birmingham
Unknown status

Wed, 14 Aug 2013 12:00:00 EDT

Pharmacogenetics of Alcohol: Treatment Implications

Conditions:   Alcohol Related Disorders;   Alcoholism;   Alcohol Abuse
Interventions:   Drug: dutasteride + ethanol;   Drug: placebo medication + ethanol;   Drug: dutasteride + placebo alcohol;   Drug: placebo medication + placebo alcohol
Sponsors:   UConn Health;   National Institutes of Health (NIH);   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Completed

Thu, 14 Aug 2008 12:00:00 EDT

A Study to Investigate the Pharmacokinetic Drug Interactions Between Dutasteride and Tadalafil in Healthy Male Subjects

Condition:   Benign Prostate Hyperplasia
Interventions:   Drug: Tadalafil;   Drug: Dutasteride
Sponsor:   Yuyu Pharma, Inc.
Completed

Wed, 20 Jul 2016 12:00:00 EDT

Dutasteride in Treating Patients With Recurrent Prostate Cancer That Did Not Respond to Androgen-Deprivation Therapy

Condition:   Prostate Cancer
Intervention:   Drug: dutasteride
Sponsor:   Roswell Park Cancer Institute
Completed

Thu, 23 Nov 2006 12:00:00 EST

Dutasteride Followed By Ultrasound-Guided Biopsy in Finding Prostate Cancer

Condition:   Prostate Cancer
Interventions:   Drug: dutasteride;   Other: placebo
Sponsors:   Sidney Kimmel Cancer Center at Thomas Jefferson University;   National Cancer Institute (NCI)
Completed

Fri, 10 Nov 2006 12:00:00 EST

Effect Of Dutasteride On Intraprostatic Dihydrotestosterone (DHT) Levels

Condition:   Prostatic Hyperplasia
Intervention:   Drug: Dutasteride
Sponsor:   GlaxoSmithKline
Completed

Tue, 17 Jun 2003 12:00:00 EDT

Dutasteride to Treat Women With Menstrually Related Mood Disorders

Conditions:   Premenstrual Syndrome;   PMS;   Healthy;   Depression
Interventions:   Drug: Dutasteride;   Drug: Placebo oral capsule
Sponsor:   National Institute of Mental Health (NIMH)
Completed

Wed, 28 Apr 2004 12:00:00 EDT

28-Day Study of Testosterone Co-administered With Dutasteride in Hypogonadal Men

Conditions:   Hypogonadism;   Hypogonadism, Male
Interventions:   Drug: Nanomilled testosterone;   Drug: Nanomilled dutasteride;   Drug: commercially available dutasteride
Sponsor:   GlaxoSmithKline
Completed

Fri, 10 Nov 2006 12:00:00 EST

Study On Bioavailability And Pharmacokinetics Of Various Doses Of Testosterone Administered With And Without Dutasteride

Conditions:   Hypogonadism;   Hypogonadism, Male
Interventions:   Drug: Nanomilled testosterone;   Drug: commercially available dutasteride;   Drug: Nanomilled dutasteride
Sponsor:   GlaxoSmithKline
Completed

Thu, 16 Nov 2006 12:00:00 EST

EAT-DUTA AndroCoV Trial

Condition:   Covid19
Interventions:   Drug: Dutasteride 0.5 mg;   Drug: Azithromycin;   Drug: Nitazoxanide;   Drug: Placebo
Sponsor:   Corpometria Institute
Completed

Thu, 28 Jan 2021 12:00:00 EST

Dutasteride and Flex Dose of Tamsulosin on as Needed Basis, to Treat Benign Prostatic Hyperplasia

Condition:   Benign Prostatic Hyperplasia
Intervention:   Drug: Tamsulosin
Sponsors:   Siami, Paul F., M.D.;   GlaxoSmithKline
Completed

Thu, 19 Jun 2008 12:00:00 EDT

Drug Use Investigation for AVOLVE(BPH)

Condition:   Prostatic Hyperplasia
Intervention:   Drug: Dutasteride
Sponsor:   GlaxoSmithKline
Completed

Mon, 20 Jun 2011 12:00:00 EDT

Study to Compare the Efficacy and Safety of Combination Treatment With Dutasteride and Tamsulosin With Tamsulosin Monotherapy, in Men With Moderate to Severe Benign Prostatic Hyperplasia

Condition:   Prostatic Hyperplasia
Interventions:   Drug: Dutasteride 0.5mg capsules;   Drug: Dutasteride placebo capsules;   Drug: Tamsulosin 0.2mg tablets;   Drug: Disintegrating placebo tamsulosin tablet
Sponsor:   GlaxoSmithKline
Completed

Mon, 10 Feb 2014 12:00:00 EST

Efficacy and Safety of DKF-313 in Patients With Benign Prostatic Hyperplasia

Condition:   Benign Prostatic Hyperplasia
Interventions:   Drug: DKF-313;   Drug: Dutasteride;   Drug: Tadalafil;   Drug: DKF-313 placebo;   Drug: Dutasteride placebo;   Drug: Tadalafil placebo
Sponsor:   Dongkook Pharmaceutical Co., Ltd.
Not yet recruiting

Thu, 01 Jul 2021 12:00:00 EDT

Comparative Efficacy of Dutasteride Plus Tamulosin With Lifestyle Advice Versus Watchful Waiting Plus Lifestyle Advice in the Management of Treatment naïve Men With Moderately Symptomatic Benign Prostatic Hyperplasia and Prostate Enlargement

Condition:   Prostatic Hyperplasia
Interventions:   Drug: Dutasteride plus tamsulosin;   Drug: tamsulosin
Sponsor:   GlaxoSmithKline
Completed

Fri, 11 Feb 2011 12:00:00 EST

A Study Assessing a Range of Formulations of the Fixed Dose Combination Product Containing Dutasteride (0.5mg) and Tamsulosin Hydrochloride (0.2mg) to Find a Formulation Which is Bioequivalent to Harnal-D Tablets (Tamsulosin Hydrochloride, 0.2mg) in Healthy Male Subjects From North East Asia

Condition:   Prostatic Hyperplasia
Interventions:   Drug: Dutasteride (0.5mg, fasted state);   Drug: Dutasteride (0.5mg, fed state);   Drug: Fixed dose combination capsule containing dutasteride 0.5mg and tamsulosin 0.2mg (fasted state);   Drug: Fixed dose combination capsule containing dutasteride 0.5mg and tamsulosin 0.2mg (fed state);   Drug: Harnal-D Tablets with water (fasted state);   Drug: Harnal-D Tablets with water (fed state);   Drug: Harnal-D tablets without water (fasted state)
Sponsor:   GlaxoSmithKline
Completed

Mon, 19 Dec 2011 12:00:00 EST

Study of Tamsulosin and/or Dutasteride to Relieve Urinary Symptoms After Brachytherapy for Localized Prostate Cancer

Condition:   Prostate Cancer
Intervention:   Drug: tamsulosin and/or dutasteride
Sponsors:   Case Comprehensive Cancer Center;   GlaxoSmithKline
Completed

Wed, 26 Oct 2005 12:00:00 EDT

Ketoconazole, Hydrocortisone, Dutasteride and Lapatinib (KHAD-L) in Prostate Cancer

Condition:   Prostate Cancer
Interventions:   Drug: ketoconazole;   Drug: hydrocortisone;   Drug: dutasteride;   Drug: lapatinib
Sponsors:   Dana-Farber Cancer Institute;   Beth Israel Deaconess Medical Center;   Brigham and Women's Hospital;   Massachusetts General Hospital;   Prostate Cancer Foundation Clinical Research Consortium;   GlaxoSmithKline
Terminated

Thu, 06 Aug 2009 12:00:00 EDT

Safety and Pharmacokinetic Interaction Study of Tadalafil and Dutasteride

Condition:   Benign Prostate Hyperplasia
Interventions:   Drug: Tadalafil;   Drug: Dutasteride
Sponsor:   Dongkook Pharmaceutical Co., Ltd.
Completed

Mon, 16 Sep 2013 12:00:00 EDT

Dutasteride Versus Placebo and Finasteride in Men With Androgenetic Alopecia

Condition:   Androgenetic Alopecia
Interventions:   Drug: 1mg Finasteride active;   Drug: 0.02mg dutasteride;   Drug: 0.1mg dutasteride;   Drug: 0.5mg dutasteride;   Drug: Finasteride placebo;   Drug: Dutasteride placebo
Sponsor:   GlaxoSmithKline
Completed

Mon, 01 Nov 2010 12:00:00 EDT

Effects On Dihydrotestosterone Regulated Gene Expression In Benign Prostatic Hyperplasia Or Prostate Cancer

Conditions:   Benign Prostatic Hyperplasia;   Prostate Cancer
Intervention:   Drug: Dutasteride
Sponsor:   GlaxoSmithKline
Completed

Wed, 13 Sep 2006 12:00:00 EDT

"REDUCE" - A Clinical Research Study To Reduce The Incidence Of Prostate Cancer In Men Who Are At Increased Risk

Condition:   Neoplasms, Prostate
Interventions:   Drug: Dutasteride;   Drug: Placebo
Sponsor:   GlaxoSmithKline
Completed

Thu, 13 Mar 2003 12:00:00 EST

Validation of Digital Morphometry for Cancer Risk in Benign Prostate Biopsies

Condition:   Prostate Cancer
Interventions:   Drug: Dutasteride;   Drug: Placebo
Sponsors:   University of Illinois at Chicago;   National Cancer Institute (NCI)
Completed

Wed, 09 May 2012 12:00:00 EDT

A Study To Compare Giving AVODART And FLOMAX Together Or In A Combination Capsule In The Fed And Fasted State

Condition:   Prostatic Hyperplasia
Interventions:   Drug: Treatment sequence A;   Drug: Treatment sequence B;   Drug: Treatment sequence C;   Drug: Treatment sequence D
Sponsor:   GlaxoSmithKline
Completed

Mon, 01 Oct 2007 12:00:00 EDT

Oral Androgens in Man-4: (Short Title: Oral T-4)

Condition:   Contraception
Interventions:   Drug: Testosterone Enanthate;   Drug: Dutasteride;   Other: placebo sesame oil
Sponsors:   University of Washington;   GlaxoSmithKline
Completed

Tue, 14 Nov 2006 12:00:00 EST

Treatment of Refractory Urinary Retention Secondary to Benign Prostatic Hyperplasia (BPH) With Dual Five Alpha Reductase Inhibition Combined With an Alpha Blocker

Conditions:   Urinary Retention;   Benign Prostatic Hyperplasia
Intervention:   Drug: Dutasteride
Sponsor:   Franklin D. Gaylis, MD Inc.
Completed

Tue, 20 May 2008 12:00:00 EDT

A Phase II Neoadjuvant Study of Enzalutamide, Abiraterone Acetate, Dutasteride and Degarelix in Men With Localized Prostate Cancer Pre-prostatectomy

Conditions:   Prostate Cancer;   Localized Prostate Cancer
Interventions:   Drug: Enzalutamide;   Drug: Abiraterone acetate;   Drug: Prednisone;   Drug: Dutasteride;   Drug: Degarelix
Sponsors:   Kenneth Pienta, MD;   Prostate Cancer Foundation Norway
Withdrawn

Tue, 10 Jun 2014 12:00:00 EDT

A Study To Compare 3 Different Formulations Of Tamsulosin At Steady State.

Condition:   Prostatic Hyperplasia
Intervention:   Drug: GI198745
Sponsor:   GlaxoSmithKline
Completed

Thu, 07 Feb 2008 12:00:00 EST

Dutasteride in Treating Patients With Prostate Cancer

Condition:   Prostate Cancer
Interventions:   Drug: dutasteride;   Drug: gadolinium-chelate;   Other: active surveillance;   Procedure: diffusion-weighted magnetic resonance imaging;   Procedure: functional magnetic resonance imaging;   Procedure: prostate biopsy;   Procedure: ultrasound imaging
Sponsor:   University College London Hospitals
Unknown status

Thu, 02 Sep 2010 12:00:00 EDT

Prostate Cancer Study In Men Who Have Failed First-Line Androgen Deprivation Therapy

Condition:   Neoplasms, Prostate
Interventions:   Drug: dutasteride;   Drug: placebo;   Drug: bicalutamide
Sponsor:   GlaxoSmithKline
Completed

Tue, 08 May 2007 12:00:00 EDT

Economic Analyses of the REDUCE Trial

Conditions:   Neoplasms, Prostate;   Benign Prostatic Hyperplasia;   Cancer
Interventions:   Drug: Dutasteride;   Drug: Placebo
Sponsor:   GlaxoSmithKline
Completed

Mon, 18 Apr 2011 12:00:00 EDT

Pharmacovigilance Study To Evaluate Safety Of AVODART In Subjects With Benign Prostate Hyperplasia

Condition:   Benign Prostatic Hyperplasia
Intervention:  
Sponsor:   GlaxoSmithKline
Completed

Tue, 15 Jan 2008 12:00:00 EST

Feasibility of Hormones and Radiation for Intermediate or High Risk Prostate Cancer

Condition:   Prostate Cancer
Interventions:   Drug: Bicalutamide;   Drug: Dutasteride;   Drug: Finasteride;   Radiation: Radiation
Sponsor:   University of Chicago
Active, not recruiting

Wed, 27 Apr 2011 12:00:00 EDT

Long-term Effects of Dutasteride on Architectural and Nuclear Morphometric Features of Benign Prostate Tissue

Condition:   Benign Prostate Tissue
Intervention:  
Sponsors:   University of Illinois at Chicago;   GlaxoSmithKline
Completed

Thu, 17 Nov 2011 12:00:00 EST

Observational AVODART (Dutasteride) Study In Benign Prostatic Hyperplasia Subjects - OASIS

Condition:   Prostatic Hyperplasia
Interventions:   Procedure: IPSS Questionnaire;   Procedure: EQ-5D Questionnaire
Sponsor:   GlaxoSmithKline
Completed

Fri, 21 Apr 2006 12:00:00 EDT

ARI103094-Follow-Up Study for REDUCE Study Subjects

Condition:   Neoplasms, Prostate
Intervention:   Drug: dutasteride
Sponsor:   GlaxoSmithKline
Completed

Mon, 20 Apr 2009 12:00:00 EDT

ITT-5 Mechanisms of Spermatogenesis in Man

Condition:   Gonadotropin Deficiency
Interventions:   Drug: Testosterone 1% Gel;   Drug: Acyline;   Drug: Dutasteride;   Drug: Ketoconazole;   Drug: HCG;   Drug: placebo dutasteride;   Drug: placebo ketoconazole
Sponsor:   University of Washington
Withdrawn

Wed, 28 May 2014 12:00:00 EDT

Benefits of Adherence to 5-alpha Reductase Inhibitor Treatment in Men With Enlarged Prostate: An Assessment of Medicare and Medicaid Patients Using the MarketScan Database

Condition:   Prostatic Hyperplasia
Intervention:   Drug: 5ARI
Sponsor:   GlaxoSmithKline
Completed

Mon, 20 Jun 2011 12:00:00 EDT

Metabolic Effects of Steroids in Obese Men

Conditions:   Obesity;   Insulin Resistance
Interventions:   Drug: Anastrazole;   Drug: Testosterone;   Drug: Dutasteride;   Drug: GnRH antagonist
Sponsors:   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK);   University of California, San Diego
Unknown status

Thu, 24 Sep 2009 12:00:00 EDT

Study of Enzalutamide (Formerly MDV3100) as a Neoadjuvant Therapy for Patients Undergoing Prostatectomy for Localized Prostate Cancer

Condition:   Prostate Cancer
Interventions:   Drug: Enzalutamide;   Drug: Leuprolide;   Drug: Dutasteride
Sponsors:   Pfizer;   Astellas Pharma Inc;   Medivation LLC, a wholly owned subsidiary of Pfizer Inc.
Completed

Wed, 07 Mar 2012 12:00:00 EST

Maximal Suppression of the Androgen Axis in Clinically Localized Prostate Cancer

Conditions:   Cancer;   Prostate Neoplasms
Interventions:   Drug: goserelin with dutasteride;   Drug: goserelin with bicalutamide and dutasteride;   Drug: goserelin with bicalutamide and dutasteride and ketoconazole
Sponsors:   University of Washington;   GlaxoSmithKline;   AstraZeneca
Completed

Wed, 01 Mar 2006 12:00:00 EST

Comparative Bioavailability of Two Fixed Dose Combination (FDC) Formulations of Dutasteride and Tamsulosin Hydrochloride Relative to Co-administration of Dutasteride With Tamsulosin Hydrochloride in Healthy Male Subjects Under Fed and Fasted States

Condition:   Prostatic Hyperplasia
Interventions:   Drug: Treatment sequence A;   Drug: Treatment sequence B;   Drug: Treatment sequence C
Sponsor:   GlaxoSmithKline
Completed

Wed, 09 Jul 2014 12:00:00 EDT

Combination Statin, Acetylsalicylic Acid and Dutasteride Use in Prostate Cancer

Condition:   Prostate Cancer
Intervention:  
Sponsor:   University Health Network, Toronto
Completed

Mon, 05 Sep 2011 12:00:00 EDT

Prospective Sexual Function Study for BPH Subjects

Condition:   Prostatic Hyperplasia
Interventions:   Drug: Dutasteride plus tamsulosin;   Drug: Placebo
Sponsor:   GlaxoSmithKline
Completed

Mon, 28 Jan 2013 12:00:00 EST

Establishing the Benefits of Adherence to Enlarged Prostate Treatment: A Validation Study Linking Adherence to Outcomes Using the Market Scan Database

Condition:   Prostatic Hyperplasia
Intervention:   Drug: 5-alpha Reductase Inhibitor (5ARI)
Sponsor:   GlaxoSmithKline
Completed

Mon, 27 Jun 2011 12:00:00 EDT

Dutasteride in Enlarged Prostate Economic Assessment: A Retrospective Database Pooled Analysis of Early 5-alpha Reductase Inhibitor Use

Condition:   Prostatic Hyperplasia
Intervention:   Drug: 5ARI + AB
Sponsor:   GlaxoSmithKline
Completed

Mon, 11 Apr 2011 12:00:00 EDT

Clinical and Economic Outcomes of Patients Utilizing Combination Therapy for Enlarged Prostates: A Henry Ford Database Assessment

Condition:   Prostatic Hyperplasia
Interventions:   Drug: 5ARI;   Drug: 5ARI + AB
Sponsor:   GlaxoSmithKline
Completed

Fri, 01 Jul 2011 12:00:00 EDT

Α Prospective Observational Study for the Evaluation of Disease Control and Quality of Life in Patients With Benign PROStatic hyPERplasia Under Fixed Dose combΙnaTion Treatment With Dutasteride and Tamsulosin as Well as Their qualitY of Life

Condition:   Benign Prostatic Hyperplasia
Intervention:   Other: Patients with Benign Prostate Hyperplasia
Sponsor:   Elpen Pharmaceutical Co. Inc.
Not yet recruiting

Mon, 05 Apr 2021 12:00:00 EDT

JALYN for Benign Prostatic Hyperplasia (BPH) and Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS)

Conditions:   Benign Prostatic Hyperplasia;   Chronic Prostatitis
Interventions:   Drug: Jalyn;   Drug: Placebo
Sponsors:   Dr. J. Curtis Nickel;   The Cleveland Clinic;   University of California, Los Angeles
Terminated

Fri, 12 Apr 2013 12:00:00 EDT

Testosterone and Its Metabolites in GID

Condition:   Transsexualism
Interventions:   Drug: testosterone undecanoate alone;   Drug: testosterone undecanoate plus letrozole;   Drug: testosterone undecanoate plus dutasteride
Sponsors:   Unita Complessa di Ostetricia e Ginecologia;   Schering-Plough
Completed

Mon, 05 Sep 2005 12:00:00 EDT

PROS-1-Male Hormonal Contraceptive Regimens on Prostate Tissue

Condition:   Healthy
Interventions:   Drug: Testosterone gel;   Drug: Dutasteride;   Drug: Depo-Medroxyprogesterone (DMPA);   Other: Placebo Testosterone gel;   Other: Placebo dutasteride;   Other: Placebo DMPA
Sponsors:   University of Washington;   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Completed

Fri, 22 Jun 2007 12:00:00 EDT

Study of PCUR-101 in Combination With ADT in Patients With mCRPC

Condition:   Prostate Cancer
Interventions:   Drug: PCUR-101;   Drug: Dutasteride 0.5 mg;   Drug: Abiraterone and Prednisone
Sponsor:   Pellficure Pharmaceuticals, Inc
Recruiting

Mon, 21 Dec 2020 12:00:00 EST

For Cause Prostate Biopsy in REDUCE Population Trial

Condition:   Prostate Cancer
Intervention:  
Sponsors:   The Cleveland Clinic;   GlaxoSmithKline
Completed

Wed, 08 Feb 2012 12:00:00 EST

Demonstrating the Clinical and Economic Benefit of 5 Alpha Reductase Inhibitor Adherence in Benign Prostatic Hyperplasia

Condition:   Prostatic Hyperplasia
Interventions:   Drug: Adherent with 5-alpha-reductase inhibitor (5ARI) therapy;   Drug: Non-adherent to 5ARI therapy
Sponsor:   GlaxoSmithKline
Completed

Wed, 13 Apr 2011 12:00:00 EDT

The Utility of PSADv (PSA Density Velocity) While on Dutasteride for Predicting Prostate Cancer Incidence and Grade and Stage

Condition:   Prostate Cancer
Intervention:  
Sponsor:   University Urological Associates Inc.
Unknown status

Fri, 02 Dec 2011 12:00:00 EST

An Observational Study of Dutasteride and Alpha-blocker Combination Therapy in Men With Symptomatic Benign Prostatic Hyperplasia and PSA Level Over 4 ng/mL

Condition:   Benign Prostatic Hyperplasia
Intervention:  
Sponsor:   Taipei Medical University WanFang Hospital
Unknown status

Wed, 11 May 2011 12:00:00 EDT

The Role of 5-alpha Reductase in Mediating Testosterone Actions

Condition:   Healthy
Interventions:   Drug: Testosterone Enanthate;   Drug: Dutasteride
Sponsor:   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Completed

Fri, 29 Jun 2007 12:00:00 EDT

ITT4 Intratesticular Hormonal Milieu in Man (ITT4)

Condition:   Healthy Males
Interventions:   Drug: Acyline;   Drug: Testosterone gel;   Drug: ketoconazole 400;   Drug: Ketoconazole 800;   Drug: Dutasteride;   Drug: Anastrozole;   Drug: Placebo ketoconazole
Sponsors:   University of Washington;   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Completed

Wed, 06 Oct 2010 12:00:00 EDT

Testosterone-Driven Growth-Hormone (GH) Secretion in Aging Men

Condition:   Aging
Interventions:   Drug: Placebo;   Drug: Testosterone;   Drug: Anastrazole;   Drug: Dutasteride
Sponsors:   Mayo Clinic;   GlaxoSmithKline
Completed

Mon, 03 Apr 2006 12:00:00 EDT

Clinical Progression and Costs in Benign Prostatic Hyperplasia Patients Treated With Early Versus Delayed Combination Therapy

Condition:   Benign Prostatic Hyperplasia
Interventions:   Drug: Early combination therapy;   Drug: Delayed combination therapy
Sponsor:   GlaxoSmithKline
Completed

Mon, 19 Sep 2011 12:00:00 EDT

Prostatic Artery Embolization Versus Medical Treatment in Symptomatic Benign Prostatic Hyperplasia

Condition:   Benign Prostatic Hyperplasia
Interventions:   Device: Embosphere® (Prostatic Arteries Embolization);   Drug: Drug therapy
Sponsors:   Assistance Publique - Hôpitaux de Paris;   Ministry of Health, France
Active, not recruiting

Wed, 17 Aug 2016 12:00:00 EDT

Establishing Predictors of Enlarged Prostate Treatment Adherence: Linking Symptom Improvement to Adherence

Condition:   Prostatic Hyperplasia
Intervention:   Drug: 5ARI or AB or Combination Therapy (5ARI + AB)
Sponsor:   GlaxoSmithKline
Completed

Mon, 11 Jul 2011 12:00:00 EDT

5 Alpha Reductase Inhibitors And The Risk Of Suicide And Depression

Conditions:   BPH;   Depression;   Suicide
Intervention:   Drug: 5ARI
Sponsor:   Lawson Health Research Institute
Completed

Wed, 24 Aug 2016 12:00:00 EDT

Evaluating the Impact of Early Versus Delayed 5 Alpha Reductase Inhibitor Treatment on the Risk of Emergent Surgery in Men With Benign Prostatic Hyperplasia

Condition:   Prostatic Hyperplasia
Intervention:   Drug: 5ARI + AB
Sponsor:   GlaxoSmithKline
Completed

Mon, 11 Apr 2011 12:00:00 EDT

One-year Prospective Observational Study of BMI Change Effect of 5-alpha Reductase Inhibitor in Korean BPH Patients

Condition:   Benign Prostatic Hyperplasia
Intervention:  
Sponsors:   Seoul National University Hospital;   GlaxoSmithKline;   Seoul National University Bundang Hospital
Completed

Fri, 11 May 2007 12:00:00 EDT

Benign Prostatic Hypertrophy Treatment Patterns & Outcomes: Marketscan

Condition:   Prostatic Hyperplasia
Interventions:   Drug: 5ARI;   Drug: AB
Sponsor:   GlaxoSmithKline
Completed

Mon, 28 Mar 2011 12:00:00 EDT

Prostatic Artery Embolization vs. Pharmacotherapy for LUTS/BPH

Conditions:   Benign Prostatic Hyperplasia;   Pharmacotherapy;   Prostatic Artery Embolization;   Minimally Invasive Treatment
Interventions:   Procedure: Prostatic Artery Embolization (PAE);   Drug: Pharmacotherapy
Sponsor:   Dominik Abt
Not yet recruiting

Wed, 29 Jan 2020 12:00:00 EST