E-ASTHMA: Review and much more.

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Eosinophilic asthma, also known as e-Asthma, is one of the most common subtypes of asthma diagnosed in ArtultHod.Eosinophilic asthma is produced with a large amount of eosinophils, the type of white crystalline cell, inflammation of the lungs. After this happens, it is unknown.Since the samples of lungs can be difficult to obtain, a greater amount of blood eosinophils often use their substitute for diagnosing in patients with difficult asthma. < Allergic asthma does not match Eosinophilic asthma. Ecosinophil asthma can occur in some patients ATOPIC (what It means those who tend to allergies), but it can also occur without atopic predisposition.

.When it has an increase in white blood cells, it generally has an inflammatory response, which leads to the thickening of its respiratory tract. Liquid and mucus , which can cause spasms in your respiratory tract (bronquiola) and cause asthma symptoms.

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Prevalence

ASMA inflammatory respiratory disorder,What can hinder breathing. One of the 13 people suffer from this chronic disease, and the control of deficient asthma can lead to the risk of threatening asthma attacks.

Know that most of these exacerbations are avoided if the asthma is correctly controlled.initially, it is considered a disorder, the asthma actually has Many subtypes that can change how your asthma can be better monitored.

around 5% to 10% of people with asthma asthma. While the prevalence of the presence of eosinophilic asthma is relatively unknown, the studies show that around 50% of cases of severe asthma are eosinophilic asthma.

If you are more than 35 years old when you are diagnosed with a heavy asthma, it has a higher risk diagnosed with Eosinophilic asthma.Your risk is the same regardless of your sex, and has reduced the risk of diagnosing eosinophilic asthma in your childhood and adolescent years.

Symptoms

Many symptoms of Eosinophilic Asthma are the Same as other forms of asthma, which include:

There are several symptoms that may also be present,that are generally not associated with asthma, including: / P>

While Eosinophilic Asthma is an immune response associated with allergies, many people Diagnostican does not suffer from allergies to mold, mold or other general allergens.

Diagnostic

Eosinophilic Asthma has a diagnosis. It is not considered common, even if the prevalence is considered higher than previously believed.

you usually want to see a pulmonologist if you are worried. The allerrooms and immunology can also be useful in its exhaustive evaluation.

The amount of eosinophilic cells

, Performing the number of eosinophil cells From the induced sample of sputum, it is considered a gold standard of the inflammatory cell, but it is difficult to get, intensive in labor,and a dependent observer. This often requires the use of a certain personal laboratory by experts.

When you pick up the sample, you want to make sure you do not spit saliva, but get wet with your respiratory tract.Then, the sample of cough can be analyzed in the laboratory to see if the amount of wet eosinophile will be equal to the maximum of 3%.

To help induce a spub, your medical provider or respiratory therapist can give you a dose of salbutamola or other armored operator. Then, this treatment follows, provides a nebulized hypertensive saline solution.The highest concentration of physiological solution when the inhalation annoys the respiratory tract and helps cause cough.

Biopsy of the respiratory tract

Another way to determine if it has e-asthma, with a biopsy of the respiratory tract, which is He performed during bronchoscopy.This procedure can be used to identify abnormal cells in the diagnosis of several different pulmonary diseases.

, however, this method is not recommended as the first step in determining eosinophilic asthma, if you can get a sufficient amount of sputum, since an invasive procedure can not be received,What requires some sedation and can have complications.

Other methods

Other methods to help diagnose e-asthma.Its health care provider can verify the complete blood count (CBC) to test eosinophilia (increasing the eosinophil number).

The careful interpretation of the eosinophils of your blood will be considered by your health care provider, since the high values in your blood do not They guarantee that you have rejection of eosinophilic asthma no less.It can help your health care provider on the additional differentiation of any other symptom you have.

Other diagnoses that can be considered if it has a sublime level of eosinophil in your blood, includes a parasitic infection, a hydroeosinophil syndrome, autoimmune disorders, adrenal insufficiency, some cancers and drug reactions.

Other tests can be used to diagnose asthma. One of them is a fractional nitrogen nitrogen (porno), , which measures the amount of nitrogen oxide on your breath when exhaled.High levels are a possible indication of pulmonary inflammation, which can be a reaction to an allergen.

Many factors can affect the results of the FENO test, including the use of steroids, age, gender, atopy (tendency to develop allergies) and smoking status. Although Feno can play a useful role to determine if someone you have to say, asthma, can not be reviewed to Aloni to diagnose the condition or predict how it can progress,In accordance with the updated recommendations for asthmatic management issued in December 2020.

Sometimes, the blood test is performed as part of the asthma procedure to measure the periosteal levels, biomarker in the epithelial cells of the tract respiratory.The levels of perioster generally increase in response to asthma, which activates certain immune cells (TH2).

However, while in some studies it was shown that the testing test is an excellent replacement of sputum tests, and other results were variable.The biggest blood of sputum and eosinophila is still preferable for shadow and periostein according to most doctors and guidelines.

Periostein – biomarker in the epithelial cells of the respiratory tract.Periostestine levels generally increase in asthma, which activates certain immune cells (TH2), and in some studies it has been shown that in some studies an excellent substitute for sputum tests.

But the results are variable in other studies, and the test is not easily accessible. The induced sputum and eosinophila blood are still preferable for size and periosce according to most doctors and guidelines.

Treatment

The first treatment of eosinophilic asthma should include its standard treatment of asthma rarity.Often, it will experience good results of inhaled corticosteroids (ICS), which are used as part of the standard asthma treatment guidelines.

If your health care provider diagnosed you eosinophilic asthma, you can change the standard approach used with inhaled corticosteroids.Los Farmacos de Corpoesteroid Include:

  • Qvar (BeclometsOne Sofriionda HFA)
  • Pulmicort (Buddhastones)
  • Flovent
  • Asmax (mometasone)
  • azmacort (triamcinoloneatonide)

, when inhaled corticosteroids often have useful effects, some people have an eosinophilic asthma that simply significant their asthma does not have a symptomatic or clinical profit of corticosteroids in the form of corticosteroids.

If you tried one or more unused inhaled corticosteroids, your doctor probably activates your attention for asthma to enable additional treatment options, always existing armored keps (included in inhalers Combined,Like Advair and Symbicort), as well as / or leukotriene modifiers, as Montelukast.If standard accelerator methods are not enough to control your asthma, you can discuss some of the most recently been discovered medications for eosinophils specifically target in eosinophilic asthma.

There are four target therapies that have approved the approval of the United States.Food and Drug Administration (FDA) for the treatment of allergic asthma: / P>

  • MITA ( Mepolizumab) previously known as bait, the monoclonal antibody is newly interleukin-5 (il-5) / Li>
  • Cinqair (ReslizAb), another monoclonal antibody against the IL5 receiver
  • fasenra (bellizumab),Another monoclonal agasint5 antibody receiver
  • Dupixent (Dupilumab), specified for The treatment of moderate decent eosinophilic asthma in patients 12 years or more. .Of these, Omalizumab tends to be less successful, since it affects allergies more specifically than Mepolizumab and Reslizumab.

    These medications are also generally well tolerated with minimal side effects with the probability that it can also reduce the use of corticosteroids.Minimizing the use of steroids also brings a decrease in side effects that can improve quality of life.

    Monitor

    It is recommended, it is recommended, since objective therapy is not a medication, but a treatment.Prepare for periodic tests and discuss the following with your health care provider in the subsequent purpose:

    • Test of the functions of the pulmonary function
    • ,Since the last visit (improved or deterioration)
    • frequency of exacerbation of asthma
    • permission of complications,As the loss of odor

    • general health status
    • functions of the living room

    I accompanied it is approximately two, there are weeks after Start of a new medicine.If you have experienced positive results, it will continue in the prescribed preparation and followed by one to six months.Even if it is not in one of the newest asthma medications focused on eosinophils, most of the doctor should see approximately once every three months to evaluate and control chronic resistance.

    Word get Information Meds

    While eosinophilic asthma is often associated with severe asthma, treatment is possible if it is diagnosed correctly.It is likely that non-processed eosinophile asthma will lead to the difficulty of controlling asthma’s aggravation, which not only worsens the quality of life, but can be potentially deadly.Working with your pulmonologist or an allergologist / immunologist with directed therapy can help you return the quality of life it deserves, and can reduce the frequency of the exacerbates of your asthma.

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