Full text biomedical articles

Evaluation of Drug-Drug Interactions between Direct-Acting Anti-Hepatitis C Virus Combination Regimens and the HIV-1 Antiretroviral Agents Raltegravir, Tenofovir, Emtricitabine, Efavirenz, and Rilpivirine

Amit Khatri, Sandeep Dutta, Martin Dunbar, Thomas Podsadecki, Roger Trinh, Walid Awni, Rajeev Menon
Antimicrob Agents Chemother. 2016 May; 60(5): 2965–2971. Prepublished online 2016 Mar 7. Published online 2016 Apr 22. doi: 10.1128/AAC.02605-15

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Race/Ethnicity and Protease Inhibitor Use Influence Plasma Tenofovir Exposure in Adults Living with HIV-1 in AIDS Clinical Trials Group Study A5202

Cindy J. Bednasz, Charles S. Venuto, Qing Ma, Eric S. Daar, Paul E. Sax, Margaret A. Fischl, Ann C. Collier, Kimberly Y. Smith, Camlin Tierney, Edward P. Acosta, Donald E. Mager, Gene D. Morse
Antimicrob Agents Chemother. 2019 Apr; 63(4): e01638-18. Prepublished online 2019 Jan 14. Published online 2019 Mar 27. doi: 10.1128/AAC.01638-18

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Combination of Tenofovir and Emtricitabine with Efavirenz Does Not Moderate Inhibitory Effect of Efavirenz on Mitochondrial Function and Cholesterol Biosynthesis in Human T Lymphoblastoid Cell Line

Min Li, Anuoluwapo Sopeyin, Elijah Paintsil
Antimicrob Agents Chemother. 2018 Sep; 62(9): e00691-18. Prepublished online 2018 Jul 16. Published online 2018 Aug 27. doi: 10.1128/AAC.00691-18

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The triple combination of tenofovir, emtricitabine and efavirenz shows synergistic anti-HIV-1 activity in vitro: a mechanism of action study

Joy Y Feng, John K Ly, Florence Myrick, Derrick Goodman, Kirsten L White, Evguenia S Svarovskaia, Katyna Borroto-Esoda, Michael D Miller
Retrovirology. 2009; 6: 44. Published online 2009 May 13. doi: 10.1186/1742-4690-6-44

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Plasma Tenofovir, Emtricitabine, and Rilpivirine and Intracellular Tenofovir Diphosphate and Emtricitabine Triphosphate Pharmacokinetics following Drug Intake Cessation

Laura Dickinson, H. Manisha Yapa, Akil Jackson, Graeme Moyle, Laura Else, Alieu Amara, Saye Khoo, David Back, Zeenat Karolia, Chris Higgs, Marta Boffito
Antimicrob Agents Chemother. 2015 Oct; 59(10): 6080–6086. Prepublished online 2015 Jul 20. Published online 2015 Sep 18. doi: 10.1128/AAC.01441-15

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Differential Skeletal Impact of Tenofovir Disoproxil Fumarate in Young versus Old HIV-Infected Adults

Philip M. Grant, Douglas Kitch, Grace A. McComsey, Camlin Tierney, Belinda Ha, Todd T. Brown
HIV Clin Trials. Author manuscript; available in PMC 2015 Jun 15.
Published in final edited form as: HIV Clin Trials. 2015 Mar-Apr; 16(2): 66–71. Published online 2015 Apr 15. doi: 10.1179/1528433614Z.0000000010

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Global epidemiology of drug resistance after failure of WHO recommended first-line regimens for adult HIV-1 infection: a multicentre retrospective cohort study

The TenoRes Study Group
Lancet Infect Dis. 2016 May; 16(5): 565–575. doi: 10.1016/S1473-3099(15)00536-8

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Long-term virological suppression on first-line efavirenz + tenofovir + emtricitabine/lamivudine for HIV-1

AIDS. 2019 Mar 15; 33(4): 745–751. Published online 2019 Jan 3. doi: 10.1097/QAD.0000000000002126

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Bictegravir/Emtricitabine/Tenofovir Alafenamide: A Review in HIV-1 Infection

Emma D. Deeks
Drugs. 2018; 78(17): 1817–1828. Published online 2018 Nov 20. doi: 10.1007/s40265-018-1010-7

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Exploring an alternative explanation for the second phase of viral decay: Infection of short-lived cells in a drug-limited compartment during HAART

Steven Sanche, Thibault Mesplède, Nancy L. Sheehan, Jun Li, Fahima Nekka
PLoS One. 2018; 13(7): e0198090. Published online 2018 Jul 17. doi: 10.1371/journal.pone.0198090

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A Review and Clinical Understanding of Tenofovir: Tenofovir Disoproxil Fumarate versus Tenofovir Alafenamide

Chanie Wassner, Nicole Bradley, Yuman Lee
J Int Assoc Provid AIDS Care. 2020 Jan-Dec; 19: 2325958220919231. Published online 2020 Apr 15. doi: 10.1177/2325958220919231

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Drug resistance outcomes of long-term ART with tenofovir disoproxil fumarate in the absence of virological monitoring

Giovanni Villa, Richard O Phillips, Colette Smith, Alexander J Stockdale, Alessandra Ruggiero, Apostolos Beloukas, Lambert T Appiah, David Chadwick, Fred S Sarfo, Anna Maria Geretti
J Antimicrob Chemother. 2018 Nov; 73(11): 3148–3157. Published online 2018 Jul 18. doi: 10.1093/jac/dky281

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Bone Mineral Density and Fractures in Antiretroviral-Naive Persons Randomized to Receive Abacavir-Lamivudine or Tenofovir Disoproxil Fumarate-Emtricitabine Along With Efavirenz or Atazanavir-Ritonavir: AIDS Clinical Trials Group A5224s, a Substudy of ACTG A5202

Grace A. McComsey, Douglas Kitch, Eric S. Daar, Camlin Tierney, Nasreen C. Jahed, Pablo Tebas, Laurie Myers, Kathleen Melbourne, Belinda Ha, Paul E. Sax
J Infect Dis. 2011 Jun 15; 203(12): 1791–1801. doi: 10.1093/infdis/jir188

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Changes in Fat Mitochondrial DNA and Function in Subjects Randomized to Abacavir-Lamivudine or Tenofovir DF–Emtricitabine With Atazanavir-Ritonavir or Efavirenz: AIDS Clinical Trials Group Study A5224s, Substudy of A5202

Grace A. McComsey, Eric S. Daar, MaryAnn O'Riordan, Ann C. Collier, Lisa Kosmiski, Jorge L. Santana, Carl J. Fichtenbaum, Heidi Fink, Paul E. Sax, Daniel E. Libutti, Mariana Gerschenson
J Infect Dis. 2013 Feb 15; 207(4): 604–611. Published online 2012 Nov 29. doi: 10.1093/infdis/jis720

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A Mathematical Model to Predict HIV Virological Failure and Elucidate the Role of Lymph Node Drug Penetration

S Sanche, N Sheehan, T Mesplède, MA Wainberg, J Li, F Nekka
CPT Pharmacometrics Syst Pharmacol. 2017 Jul; 6(7): 469–476. Published online 2017 May 27. doi: 10.1002/psp4.12200

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Safety and tolerability of Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Disoproxil fumarate in a real life setting: Data from surveillance cohort long-term toxicity antiretrovirals/antivirals (SCOLTA) project

Nicola Squillace, Elena Ricci, Tiziana Quirino, Andrea Gori, Alessandra Bandera, Laura Carenzi, Giuseppe Vittorio De Socio, Giancarlo Orofino, Canio Martinelli, Giordano Madeddu, Stefano Rusconi, Paolo Maggi, Benedetto Maurizio Celesia, Laura Cordier, Francesca Vichi, Leonardo Calza, Katia Falasca, Antonio Di Biagio, Giovanni Francesco Pellicanò, Paolo Bonfanti, for the CISAI Study Group
PLoS One. 2017; 12(6): e0179254. Published online 2017 Jun 20. doi: 10.1371/journal.pone.0179254

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A Randomized Comparative Trial of Continued Abacavir/Lamivudine plus Efavirenz or Replacement with Efavirenz/Emtricitabine/Tenofovir DF in Hypercholesterolemic HIV-1 Infected Individuals

Graeme J. Moyle, Chloe Orkin, Martin Fisher, Jyoti Dhar, Jane Anderson, Edmund Wilkins, Jacqueline Ewan, Ramin Ebrahimi, Hui Wang, for the ROCKET 1 (Randomized Open Label Switch for Cholesterol Elevation on Kivexa Evaluation Trial) Study Group
PLoS One. 2015; 10(2): e0116297. Published online 2015 Feb 6. doi: 10.1371/journal.pone.0116297

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Antiretroviral therapy for pregnant women living with HIV or hepatitis B: a systematic review and meta-analysis

Reed A Siemieniuk, Farid Foroutan, Reza Mirza, Jinell Mah Ming, Paul E Alexander, Arnav Agarwal, Olufunmilayo Lesi, Arnaud Merglen, Yaping Chang, Yuan Zhang, Hassan Mir, Elliot Hepworth, Yung Lee, Dena Zeraatkar, Gordon H Guyatt
BMJ Open. 2017; 7(9): e019022. Published online 2017 Sep 11. doi: 10.1136/bmjopen-2017-019022

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Rilpivirine use in the Swiss HIV cohort study: a prospective cohort study

Delphine Sculier, Angèle Gayet-Ageron, Manuel Battegay, Matthias Cavassini, Jan Fehr, Cedric Hirzel, Patrick Schmid, Enos Bernasconi, Alexandra Calmy, for the Swiss HIV Cohort Study
BMC Infect Dis. 2017; 17: 476. Published online 2017 Jul 6. doi: 10.1186/s12879-017-2579-2

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Patient-Reported Outcomes After a Switch to a Single-Tablet Regimen of Rilpivirine, Emtricitabine, and Tenofovir DF in HIV-1-Positive, Virologically Suppressed Individuals: Additional Findings From a Randomized, Open-Label, 48-Week Trial

Jason Brunetta, Santiago Moreno Guillén, Andrea Antinori, Patrick Yeni, Barbara Wade, Margaret Johnson, Peter Shalit, Ramin Ebrahimi, Bethsheba Johnson, Ivan Walker, Shampa De-Oertel
Patient. 2015; 8(3): 257–267. Published online 2015 Mar 26. doi: 10.1007/s40271-015-0123-2

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