How often can you take Aleve? Correct dosage information


Alev is a non-steroidal anti-inflammatory drug (NSAID) used to relieve pain and reduce fever. It is a brand name for naproxen . It is available over the counter (OTC) and by prescription.

Like generic naproxen and its other brands, Aleve is anti-inflammatory. People use it to manage many things, including:

It is important to follow your doctor's recommendations to avoid possible side effects.

This article discusses Aleve dosage, safety, side effects, and drug interactions. It also covers precautions to keep in mind when taking Aleve.

Illustration by Emily Roberts, Get Drug Information


Aleve comes in capsule and gel form. One dose of OTC Aleve contains 220 mg of naproxen and 20 mg of sodium.

Prescription naproxen is available in both regular and extended-release forms. Also available in combination with sleeping pills: 25 milligrams (mg) of diphenhydramine hydrochloride.

As with all NSAIDs, you should aim for the lowest effective dose for the shortest period of time possible. According to the manufacturer, the doses for pain relief are as follows:

  • Take one tablet every 8-12 hours.
  • For the first dose, you can take two tablets in an hour.

After the first dose, you should not take more than two tablets in 8-12 hours, or more than three tablets in 24 hours.

Missed dose

If you miss a dose, you can skip it or take it as soon as you remember. Then wait 12 hours before taking your next dose. Follow your usual dosing schedule if possible.

Never take this medicine twice.

How to store

In a safe environment, keep Aleve tightly closed in the container in which it was delivered. It should be stored at room temperature, away from sources of heat and humidity.

Get rid of outdated or unnecessary medications. As an added precaution, you can mix the medicine with something unwanted, such as used coffee grounds, dirt, or kitty litter, before throwing it away.

Also, some pharmacies accept unwanted drugs so they can be disposed of properly. Keep Naproxen out of the reach of children.


Your doctor will advise you on how to take your medications. It is important to carefully follow their directions and directions on the packaging. Pharmacists will answer any questions about medications you may have.


All NSAIDs, including naproxen, work by blocking the body's production of chemicals known as prostaglandins . Prostaglandins contribute to inflammation , including swelling, fever, and pain.

Some of the common side effects include:

Naproxen is generally safe, but it is associated with serious and even deadly side effects . These include complications of the gastrointestinal tract, kidneys, and heart.

Since the side effects of this drug can be quite serious, you should only take Aleve under the supervision of a doctor. Also, it is best not to take more than the recommended dose for the shortest time necessary.

Allergic reaction

This medicine may cause an allergic reaction. Such a reaction can manifest as:

If you experience any of these symptoms, stop taking naproxen and seek emergency medical attention.

Stomach bleeding

Prostaglandins naturally protect the stomach from damage. Therefore, when Aleve reduces the production of prostaglandins, it can cause stomach bleeding .

Signs and symptoms of stomach bleeding include:

  • Severe abdominal pain
  • Black tarry stools
  • Bloody stools
  • Vomiting blood

Seek medical attention immediately if you experience any of these effects.

Cardiovascular risks

Based on the research findings, the US Food and Drug Administration (FDA) has required manufacturers to strengthen their warnings about cardiovascular health risks on the packaging and labeling of NSAIDs.

These risks include:

You can have these effects even if you only take NSAIDs for a few weeks. Taking higher doses for longer periods of time can increase your risk.

However, a 2016 Danish study found a link between short-term treatment with ibuprofen or diclofenac and cardiovascular events. However, he did not identify a specific link between naproxen and similar events.

Symptoms to watch out for

Symptoms that may indicate cardiovascular side effects that require immediate attention include:

  • Fluid retention
  • Chest pain
  • Soft spot
  • Difficulty breathing
  • Speak slurred
  • Vision or balance problems.

Hepatic injury

Liver damage is another possible complication when taking naproxen or other NSAIDs. Symptoms of liver problems include:

If you have any of these, stop taking naproxen and seek medical attention immediately.

Precautions and contraindications.

Alev is not for everyone. People with certain risk factors or existing medical conditions should consider other drug options.

Conditions that can increase the risk of side effects include:

  • Before or after heart bypass surgery
  • Heart disease
  • Gastrointestinal (GI) problems
  • Liver problems
  • Kidney problems
  • History of strokes

Drinking alcohol in combination with naproxen can increase your risk of stomach and gastrointestinal problems.

If you already have gastrointestinal problems, see your doctor for the right pain reliever.

Other conditions that can increase your risk of dangerous side effects from naproxen include:

Pregnant or breastfeeding

If you are pregnant or trying to conceive, you should speak to your doctor before taking Aleve. They may recommend that you avoid taking this drug or use it with caution.

This drug can cause birth defects when taken in the last trimester of pregnancy. It can also be transmitted through breast milk.


Aleve is not indicated for use in children under 12 years of age unless directed by a doctor. If your child is taking Alev or any form of naproxen, be sure to inform their doctor of any changes in their weight, as the dose is weight-dependent.


NSAIDs are associated with the risk of ulcers , bleeding in the stomach lining, and other gastrointestinal problems. Older adults may be at even higher risk for gastrointestinal complications.

These side effects can be serious. Please note that they can occur at any time and may appear without prior notice.


Contraindications include people with heart, liver, kidney, and gastrointestinal problems. Also, children under the age of 12 should not take Aleva without a prescription. If you are pregnant or breastfeeding, talk to your doctor about alternatives to Aleve.

Drug interactions and overdose

Many over-the-counter medicines contain NSAIDs. For this reason, it is imperative that you read all drug labels (over-the-counter and prescription) before using them. Also, make sure you only receive one dose of NSAIDs at a time.

Dietary supplements, herbs, recreational drugs, and caffeine can interact with naproxen and alter how it works in the body. Talk to your doctor about all the medications and supplements you are taking before taking Aleve.

Medications that can adversely interact with naproxen include:

  • Alendronate is taken to prevent bone loss
  • Other NSAIDs, including aspirin
  • Other anti-inflammatory medications (such as ibuprofen or prednisone )
  • Entecavir for hepatitis B infections
  • Cidofovir , taken for eye infections in people with HIV.
  • Cyclosporine for transplant patients
  • Water pills ( diuretics )
  • Medicines for blood pressure such as ACE inhibitors.
  • Blood thinners such as Coumadin or other medications treat or prevent blood clots.
  • Methotrexate , a chemotherapy drug
  • Pemetrexed , a chemotherapy drug
  • Plant foods that contain feverfew , garlic, ginger, or ginkgo biloba.
  • Lithium preparations such as Eskalith and Lithobid

If you think you have overdosed, call 911 or your local poison control center.


Aleve is a non-steroidal anti-inflammatory, pain reliever, and pain reliever that people often use to relieve chronic pain. The drug is dispensed without a prescription and with a prescription. You should follow your doctor's instructions for dosage. In the over-the-counter instructions, take one 220 mg tablet every 8 to 12 hours.

Get the word of drug information

Aleve may be beneficial for your condition, but to get the most out of it, you need to use it safely. Over-the-counter medications, including Aleve, must be used correctly and with care.

Be sure to follow the dosage instructions and be aware of possible side effects and interactions. If you feel like something is wrong, see your doctor .

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