Clinical Trials

Acute Bronchodilator Effects of Ipratropium/Levosalbutamol 20/50 mcg Fixed Dose Combination vs Salbutamol 100 mcg Inhaler Plus Ipratropium 20 mcg Inhalation Aerosol Free Combination in Patients With Stable COPD

Condition:   Chronic Obstructive Pulmonary Disease
Interventions:   Drug: Ipratropium/Levosalbutamol 20/50 mcg Fixed Dose Combination (2 inhalations) via pMDI;   Drug: Salbutamol 100 mcg Inhaler (2 inhalations) + Ipratropium 20 mcg Inhalation Aerosol (2 inhalations) Free Combination via MDI
Sponsor:   Neutec Ar-Ge San ve Tic A.Ş
Withdrawn

Thu, 25 Jun 2020 12:00:00 EDT

Atrovent in Exercise Induced Laryngeal Obstruction (EILO)

Condition:   Exercise Induced Laryngeal Obstruction (EILO)
Intervention:   Drug: Ipratropium bromide spray
Sponsor:   Haukeland University Hospital
Completed

Fri, 29 Apr 2016 12:00:00 EDT

Ipratropium Bromide Spray as Treatment for Sialorrhea in Children

Condition:   Sialorrhea
Interventions:   Drug: Ipratropium bromide;   Other: Placebo
Sponsor:   London Health Sciences Centre
Unknown status

Tue, 20 Nov 2018 12:00:00 EST

Effectiveness of Ipratropium Bromide in Preventing Exercise-induced Bronchoconstriction in Athletes

Condition:   Bronchospasm, Exercise-Induced
Interventions:   Drug: ipratropium bromide;   Drug: Placebo
Sponsor:   University of California, San Francisco
Completed

Mon, 24 Sep 2012 12:00:00 EDT

Duration of Protective Effect From Inhaled Ipratropium Bromide on Methacholine Airway Hyperresponsiveness

Condition:   Asthma
Interventions:   Drug: ipratropium bromide;   Drug: placebo
Sponsors:   University of Saskatchewan;   Royal University Hospital Foundation
Completed

Thu, 31 Jan 2008 12:00:00 EST

PT001 MDI Versus Atrovent Study in Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)

Condition:   Chronic Obstructive Pulmonary Disease
Interventions:   Drug: PT001 MDI;   Drug: Ipratropium Bromide HFA Inhalation Aerosol;   Other: Placebo MDI
Sponsor:   Pearl Therapeutics, Inc.
Completed

Mon, 09 May 2011 12:00:00 EDT

Regular Use Effect of Inhaled Ipratropium Bromide on Airway Responsiveness to Methacholine in Well-controlled Asthma

Condition:   Asthma
Interventions:   Drug: Ipratropium Metered Dose Inhaler;   Drug: placebo metered dose inhaler
Sponsor:   University of Saskatchewan
Completed

Mon, 18 Nov 2019 12:00:00 EST

A Comparison of Levalbuterol Plus Ipratropium With Levalbuterol Alone in the Treatment of Acute Asthma Exacerbation

Condition:   Asthma
Intervention:   Drug: ipratropium
Sponsors:   MetroHealth Medical Center;   Sunovion
Completed

Mon, 31 Dec 2007 12:00:00 EST

A Study to Look at Day to Day Changes in Lung Function in COPD Subjects Taking Albuterol/Salbutamol and Ipratropium

Condition:   Pulmonary Disease, Chronic Obstructive
Interventions:   Drug: Albuterol/salbutamol;   Drug: Ipratropium
Sponsor:   GlaxoSmithKline
Completed

Mon, 24 Sep 2012 12:00:00 EDT

Study to Assess the Effect of Salbutamol and Ipratropium Bromide in Chronic Obstructive Pulmonary Disease (COPD) Patients

Condition:   COPD
Interventions:   Drug: Salbutamol;   Drug: ipratropium bromide
Sponsors:   University Hospital, Antwerp;   GlaxoSmithKline
Completed

Tue, 02 Jun 2009 12:00:00 EDT

Ipratropium Bromide in Peri-Operative COPD

Condition:   Pulmonary Disease, Chronic Obstructive
Interventions:   Drug: placebo;   Drug: ipratropium bromide
Sponsor:   Boehringer Ingelheim
Completed

Tue, 17 Sep 2013 12:00:00 EDT

Trial to Determine the Comparability of Ipratropium Bromide Hydrofluoroalkane (HFA)-134a Inhalation Aerosol to ATROVENT® Chlorofluorocarbon (CFC) Inhalation Aerosol, in Patients With Chronic Obstructive Pulmonary Disease (COPD)

Condition:   Pulmonary Disease, Chronic Obstructive
Interventions:   Drug: Ipratropium bromide HFA-134a inhalation aerosol;   Drug: Atrovent CFC inhalation aerosol
Sponsor:   Boehringer Ingelheim
Completed

Wed, 10 Sep 2014 12:00:00 EDT

Effects of Bronchodilators in Mild Chronic Obstructive Pulmonary Disease (COPD)

Condition:   Chronic Obstructive Pulmonary Disease (COPD)
Intervention:   Drug: Ipratropium Bromide
Sponsor:   Queen's University
Completed

Tue, 20 Sep 2005 12:00:00 EDT

Actuation Indicator Trial in Patients With COPD

Condition:   Pulmonary Disease, Chronic Obstructive
Intervention:   Device: Ipratropium bromide
Sponsor:   Boehringer Ingelheim
Completed

Fri, 26 Jun 2009 12:00:00 EDT

Efficacy and Safety of Tiotropium and Atrovent in Subjects With Chronic Obstructive Pulmonary Disease (COPD)

Condition:   Pulmonary Disease, Chronic Obstructive
Interventions:   Drug: Tiotropium inhalation powder capsule;   Drug: Placebo Metered Dose Inhaler;   Drug: Ipratropium Bromide Metered Dose Inhaler;   Drug: Placebo inhalation powder capsule
Sponsor:   Boehringer Ingelheim
Completed

Tue, 24 Jun 2014 12:00:00 EDT

Feasibility, Safety and Efficacy of Nebulized Long-Acting Bronchodilators (Formoterol and Revefenacin) vs. Short-Acting Bronchodilators (Albuterol and Ipratropium) in Hospitalized Patients With AECOPD

Condition:   COPD Exacerbation
Interventions:   Drug: Revefenacin (YUPELRI) & Formoterol (Perforomist);   Drug: Albuterol Inhalation Aerosol (short-acting beta-agonists) & Ipratropium Aerosol (short-acting anticholinergic)
Sponsors:   University of Tennessee Graduate School of Medicine;   Mylan Pharmaceuticals
Recruiting

Mon, 07 Dec 2020 12:00:00 EST

Postmarketing Surveillance Study of Atrovent® in Chronic Obstructive Airways Disease

Condition:   Pulmonary Disease, Chronic Obstructive
Intervention:   Drug: Atrovent®
Sponsor:   Boehringer Ingelheim
Completed

Thu, 11 Sep 2014 12:00:00 EDT

Defining and Treating Depression-related Asthma

Conditions:   Asthma;   Depression;   Childhood Asthma
Intervention:   Drug: Ipratropium Bromide
Sponsor:   State University of New York at Buffalo
Completed

Thu, 05 Nov 2020 12:00:00 EST

Effect of Ipratropium on Acute Bronchitis in Subjects Without Underlying Lung Disease

Condition:   Bronchitis
Intervention:   Drug: ipratropium
Sponsor:   Kaiser Permanente
Completed

Mon, 04 Sep 2006 12:00:00 EDT

Safety Trial of Atrovent® in Pediatric Patients With Rhinorrhea Associated With a Common Cold or Allergy

Condition:   Cold
Intervention:   Drug: Atrovent®
Sponsor:   Boehringer Ingelheim
Completed

Fri, 12 Sep 2014 12:00:00 EDT

Postmarketing Surveillance of Atrovent® in Chronic Obstructive Pulmonary Disease

Condition:   Pulmonary Disease, Chronic Obstructive
Intervention:   Drug: Atrovent® inhalets
Sponsor:   Boehringer Ingelheim
Completed

Fri, 12 Sep 2014 12:00:00 EDT

Ipratropium or Salbutamol Sulphate Alone or Combination Therapy Salbutamol and Ipratropium in Patients With COPD

Condition:   Pulmonary Disease, Chronic Obstructive
Interventions:   Drug: Ipratropium bromide 500 µg/salbutamol sulphate 3 mg;   Drug: Ipratropium 500 µg;   Drug: Salbutamol sulphate 3 mg;   Drug: Salbutamol sulphate 6 mg
Sponsor:   Boehringer Ingelheim
Completed

Tue, 08 Jul 2014 12:00:00 EDT

Postmarketing Surveillance Study of Atrovent® Inhalets in Chronic Obstructive Airways Disease

Condition:   Pulmonary Disease, Chronic Obstructive
Intervention:   Drug: ATROVENT® inhalets
Sponsor:   Boehringer Ingelheim
Completed

Fri, 12 Sep 2014 12:00:00 EDT

Postmarketing Surveillance Study of Atrovent® Inhalets in Chronic Obstructive Pulmonary Disease

Condition:   Pulmonary Disease, Chronic Obstructive
Intervention:   Drug: Atrovent® inhalets
Sponsor:   Boehringer Ingelheim
Completed

Fri, 12 Sep 2014 12:00:00 EDT

Postmarketing Surveillance Study of Atrovent® Inhaletten® in Chronic Obstructive Airways Disease

Condition:   Pulmonary Disease, Chronic Obstructive
Intervention:   Drug: Atrovent® Inhaletten
Sponsor:   Boehringer Ingelheim
Completed

Fri, 12 Sep 2014 12:00:00 EDT

Post-marketing Surveillance of Atrovent® in Chronic Obstructive Pulmonary Disease

Condition:   Pulmonary Disease, Chronic Obstructive
Intervention:   Drug: Atrovent® - inhalets
Sponsor:   Boehringer Ingelheim
Completed

Tue, 09 Sep 2014 12:00:00 EDT

Post-marketing Surveillance of Atrovent® Inhalets in Chronic Obstructive Pulmonary Disease

Condition:   Pulmonary Disease, Chronic Obstructive
Intervention:   Drug: Atrovent® - inhalets
Sponsor:   Boehringer Ingelheim
Completed

Tue, 09 Sep 2014 12:00:00 EDT

Postmarketing Surveillance Study of Atrovent® Inhalation Solution in Chronic Obstructive Pulmonary Disease

Condition:   Pulmonary Disease, Chronic Obstructive
Intervention:   Drug: Atrovent® Inhalation Solution
Sponsor:   Boehringer Ingelheim
Completed

Fri, 12 Sep 2014 12:00:00 EDT

Acute Bronchodilator Effect of Inhaled Albuterol Sulfate and Ipratropium Bromide in Patients With Stable COPD

Condition:   COPD
Interventions:   Combination Product: Albuterol Sulfate and Ipratropium Bromide;   Combination Product: Albuterol Sulfate
Sponsor:   Pneuma Respiratory, Inc
Completed

Thu, 29 Mar 2018 12:00:00 EDT

Study to Assess the Safety of Ipratropium Bromide, in Patients With Chronic Obstructive Pulmonary Disease (COPD)

Condition:   Pulmonary Disease, Chronic Obstructive
Interventions:   Drug: Ipratropium Bromide low dose;   Drug: Placebo;   Drug: Ipratropium Bromide high dose
Sponsor:   Boehringer Ingelheim
Completed

Wed, 10 Sep 2014 12:00:00 EDT

Ipratropium Spray for Drooling Saliva in Parkinson's Disease

Condition:   Parkinson's Disease
Intervention:   Drug: ipratropium bromide (drug)
Sponsors:   University Health Network, Toronto;   Parkinson's Disease Foundation
Completed

Mon, 27 Feb 2006 12:00:00 EST

Treatment of Clozapine-Induced Hypersalivation Ipratropium Bromide

Condition:   Hypersalivation
Intervention:   Drug: ipratropium bromide 0.03% spray
Sponsor:   Centre for Addiction and Mental Health
Completed

Thu, 28 Sep 2006 12:00:00 EDT

Comparison of Tiotropium Inhalation Capsules and Atrovent Metered Dose Inhaler (MDI) in a Efficacy and Safety Study in Adults With Chronic Obstructive Pulmonary Disease

Condition:   Pulmonary Disease, Chronic Obstructive
Interventions:   Drug: tiotropium inhalation powder capsules;   Drug: Atrovent;   Drug: placebo to Atrovent;   Drug: placebo to tiotropium inhalation capsules
Sponsor:   Boehringer Ingelheim
Completed

Tue, 24 Jun 2014 12:00:00 EDT

Study of the Comparability of Ipratropium Bromide Hydrofluoroalkane (HFA)-134a Inhalation Aerosol to the Market Standard, Atrovent® Chlorofluorocarbon (CFC) Inhalation Aerosol, in Patients With Chronic Obstructive Pulmonary Disease

Condition:   Pulmonary Disease, Chronic Obstructive
Interventions:   Drug: Ipratropium bromide HFA-134a inhalation aerosol;   Drug: Atrovent® CFC inhalation aerosol;   Drug: Placebo
Sponsor:   Boehringer Ingelheim
Completed

Thu, 09 Oct 2014 12:00:00 EDT

Sensitivity of New Exercise Tests in Chronic Obstructive Pulmonary Disease (COPD)

Condition:   Chronic Obstructive Pulmonary Disease
Interventions:   Drug: ipratropium bromide;   Drug: placebo;   Behavioral: constant rate step test;   Behavioral: constant rate shuttle walk test
Sponsors:   Laval University;   McGill University;   Boehringer Ingelheim
Completed

Fri, 12 Dec 2008 12:00:00 EST

Safety and Efficacy of Two Different Doses of Ipratropium Bromide Versus ATROVENT® Inhalation Aerosol in Adults With Chronic Obstructive Pulmonary Disease

Condition:   Pulmonary Disease, Chronic Obstructive
Interventions:   Drug: Low dose of Ipratropium bromide;   Drug: High dose of Ipratropium bromide;   Drug: Atrovent;   Drug: Placebo
Sponsor:   Boehringer Ingelheim
Completed

Fri, 27 Jun 2014 12:00:00 EDT

Combivent Respimat 1-year Safety Study in Patients With Chronic Obstructive Pulmonary Disease

Condition:   Pulmonary Disease, Chronic Obstructive
Interventions:   Drug: Combivent CFC-MDI;   Drug: Combivent Respimat 20/100 mcg;   Drug: Atrovent HFA 42 mcg + Albuterol HFA 200 mcg
Sponsor:   Boehringer Ingelheim
Completed

Wed, 25 Nov 2009 12:00:00 EST

Study to Assess the Efficacy of Ipratropium Bromide Associated With High Dose Salbutamol by Repeated Nebulisation Versus Repeat Nebulisation of Salbutamol Alone, in Acute Asthmatic Attacks in Young Children

Condition:   Asthma
Interventions:   Drug: Ipratropium bromide;   Drug: Placebo;   Drug: Salbutamol
Sponsor:   Boehringer Ingelheim
Terminated

Wed, 10 Sep 2014 12:00:00 EDT

Phase I, Placebo-Controlled, Blinded Pilot Study of Ipratropium in Children Admitted to the ICU With Status Asthmaticus

Condition:   Status Asthmaticus
Interventions:   Drug: Ipratropium;   Drug: 0.9% Sodium Chloride;   Drug: Albuterol;   Drug: corticosteroids
Sponsor:   University Hospitals Cleveland Medical Center
Completed

Fri, 19 Aug 2016 12:00:00 EDT

Comparison of Tiotropium and Ipratropium in a Double-Blind, Double-dummy, Efficacy and Safety Study in Adults With COPD

Condition:   Pulmonary Disease, Chronic Obstructive
Interventions:   Drug: Tiotropium;   Drug: Ipratropium
Sponsor:   Boehringer Ingelheim
Completed

Tue, 10 Jan 2006 12:00:00 EST

Single Dose Ultibro Breezhaler by Sd-DPI Versus Ipratropium/Salbutamol by Nebulizer in COPD

Condition:   COPD
Interventions:   Drug: indacaterol/glycopyrronium 110/50 Breezhaler®;   Device: Placebo by Breezhaler®;   Drug: ipratropium/salbutamol 0,5 mg, 2,5 mg by nebulisation;   Device: Placebo by nebulisation
Sponsors:   Wouter H. van Geffen;   Novartis;   University Medical Center Groningen
Completed

Thu, 15 Oct 2015 12:00:00 EDT

A Comparison of Combivent UDV (Ipratropium 500mcg and Salbutamol 2.5mg) and Salbutamol UDV Alone (2.5mg)

Condition:   Asthma
Interventions:   Drug: ipratropium plus salbutamol UDV;   Drug: salbutamol UDV
Sponsor:   Boehringer Ingelheim
Completed

Tue, 10 Jan 2006 12:00:00 EST

Comparative Pharmacokinetics and Pharmacodynamics of Tiotropium With Ipratropium or Placebo After 19 Days of Tiotropium Treatment

Condition:   Healthy
Interventions:   Drug: Ipratropium - unit dose vial;   Drug: Tiotropium - inhalation capsule;   Drug: Placebo matching tiotropium;   Drug: Placebo matching ipratropium
Sponsor:   Boehringer Ingelheim
Completed

Tue, 24 Jun 2014 12:00:00 EDT

Magnesium Sulfate Versus Ipratropuim Bromide in Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Condition:   COPD Exacerbation
Interventions:   Drug: Ipratropium bromide;   Drug: Magnesium Sulfate
Sponsor:   University of Monastir
Completed

Thu, 03 Jun 2010 12:00:00 EDT

Efficacy and Safety of Tiotropium Inhalation Capsules and Atrovent MDI in Patients With Chronic Obstructive Pulmonary Disease (COPD)

Condition:   Pulmonary Disease, Chronic Obstructive
Interventions:   Drug: tiotropium inhalation capsules (18 mcg once daily);   Drug: Atrovent MDI (2 puffs of 20 mcg(q.i.d.) in patients
Sponsor:   Boehringer Ingelheim
Completed

Tue, 10 Jan 2006 12:00:00 EST

Efficacy and Safety of Combivent® Aerosol and Spacer, in Adult Patients With Moderate to Severe Asthma Crisis

Condition:   Asthma
Intervention:   Drug: salbutamol sulfate + ipratropium bromide
Sponsor:   Boehringer Ingelheim
Terminated

Tue, 08 Jul 2014 12:00:00 EDT

Assessment of Ventilation-perfusion Abnormalities in Patients With Stable Smoking-related Airways Disease

Condition:   Chronic Obstructive Pulmonary Disease
Interventions:   Drug: salbutamol + ipratropium bromide nebules;   Drug: nebulized saline
Sponsors:   Imperial College London;   GlaxoSmithKline
Terminated

Fri, 16 Sep 2005 12:00:00 EDT

Evaluation of Benefit of Nebulized Bronchodilators at Home in Severe Chronic Obstructive Pulmonary Disease and Very Severe Steady State

Condition:   Severe Chronic Obstructive Pulmonary Disease
Interventions:   Drug: Atrovent + Bricanyl or Atrovent + Ventoline;   Drug: Placebo
Sponsor:   University Hospital, Tours
Completed

Thu, 03 Apr 2014 12:00:00 EDT

A Comparison of 18g of Tiotropium Inhalation Capsules Once Daily and Atrovent Metered Dose Inhaler (2 Puffs of 20g, 4 Times Daily) in a Double-Blind, Double-Dummy, Efficacy and Safety Study in Adults With Chronic Obstructive Pulmonary Disease (COPD)

Condition:   Pulmonary Disease, Chronic Obstructive
Interventions:   Drug: tiotropium inhalation powder capsule;   Drug: ipratropium bromide Metered Dose Inhaler
Sponsor:   Boehringer Ingelheim
Completed

Mon, 17 Oct 2005 12:00:00 EDT

Ipratropium Bromide/Salbutamol Delivered by the Respimat® Inhaler Compared to Ipratropium Bromide Respimat®, COMBIVENT® Inhalation Aerosol and Placebo in Adults With Chronic Obstructive Pulmonary Disease

Condition:   Pulmonary Disease, Chronic Obstructive
Interventions:   Drug: Ipratropium bromide / Salbutamol;   Drug: Placebo Inhalation solution;   Drug: Ipratropium bromide;   Drug: COMBIVENT Inhalation Aerosol;   Drug: Placebo Inhalation Aerosol
Sponsor:   Boehringer Ingelheim
Completed

Fri, 27 Jun 2014 12:00:00 EDT

Bronchodilator's Effects on Exertional Dyspnoea in Pulmonary Arterial Hypertension

Condition:   Pulmonary Arterial Hypertension
Interventions:   Drug: Nebulized ipratropium bromide;   Drug: Nebulized combination ipratropium bromide with salbutamol;   Drug: Nebulized Placebo
Sponsor:   Assistance Publique - Hôpitaux de Paris
Withdrawn

Wed, 25 May 2016 12:00:00 EDT

Cryobiopsy Study to Assess Drug Distribution in Subjects With Suspected Interstitial Lung Disease

Condition:   Lung Diseases, Interstitial
Interventions:   Drug: Ipratropium Bromide;   Procedure: Flexible Bronchoscopy/Biopsy
Sponsors:   GlaxoSmithKline;   University College London Hospitals
Completed

Tue, 02 May 2017 12:00:00 EDT

Revefenacin in Acute Respiratory Insufficiency in COPD

Conditions:   COPD;   Acute Respiratory Failure
Interventions:   Drug: Revefenacin Inhalation Solution [Yupelri];   Drug: Ipratropium Bromide
Sponsors:   University of California, Los Angeles;   Theravance Biopharma;   Mylan Pharmaceuticals
Recruiting

Thu, 19 Mar 2020 12:00:00 EDT

The Effects Of Bronchodilator Therapy On Respiratory And Autonomic Function In Patients With Familial Dysautonomia

Condition:   Familial Dysautonomia
Interventions:   Drug: Albuterol-sulphate;   Drug: Ipratropium-bromide;   Other: placebo
Sponsor:   NYU Langone Health
Completed

Tue, 19 Nov 2013 12:00:00 EST

Evaluation of Breathing Pattern and Dyspnea in Subjects With Tetraplegia

Conditions:   Dyspnea;   Tetraplegia
Intervention:   Drug: ipratropium (Atrovent)
Sponsor:   US Department of Veterans Affairs
Completed

Tue, 19 May 2009 12:00:00 EDT

Mechanisms for Dyspnea on Exertion in Children With Obesity and Asthma: Distinct Physiological Phenotypes

Conditions:   Asthma in Children;   Dyspnea; Asthmatic;   Obesity, Childhood
Interventions:   Other: Control;   Drug: Albuterol;   Drug: Ipratropium Bromide
Sponsors:   Ohio State University;   Nationwide Children's Hospital
Not yet recruiting

Tue, 03 Dec 2019 12:00:00 EST

Acute Bronchodilator Response of a Single Dose of Atrovent or Berotec on Top of Pharmacodynamic Steady State of Spiriva

Condition:   Pulmonary Disease, Chronic Obstructive
Interventions:   Drug: Tiotropium + placebo;   Drug: Tiotropium + ipratropium;   Drug: Tiotropium + fenoterol
Sponsor:   Boehringer Ingelheim
Completed

Tue, 10 Jan 2006 12:00:00 EST

β2-agonist Versus Ipratropium Bromide Associated With β2-agonists in Chronic Obstructive Pulmonary Disease Exacerbation

Condition:   Acute Exacerbation of Chronic Obstructive Airways Disease
Interventions:   Drug: Bricanyl/Iprovent;   Drug: Bricanyl
Sponsor:   University of Monastir
Completed

Tue, 17 Sep 2013 12:00:00 EDT

Efficacy and Tolerability Study in Severe Chronic Obstructive Pulmonary Disease (COPD) Patients

Condition:   Chronic Obstructive Pulmonary Disease (COPD)
Interventions:   Drug: Drug: Budesonide/formoterol (Symbicort Turbuhaler;   Drug: Drug: ipratropium (AtroventTM);   Drug: theophylline SR
Sponsor:   AstraZeneca
Completed

Fri, 12 Aug 2011 12:00:00 EDT

Trial of AccuPAP Device Versus Standard Nebulizer Therapy in Acute Asthma Exacerbation in Children

Condition:   Asthma
Interventions:   Device: AccuPAP;   Drug: Albuterol and Ipratropium Continuous Nebulizer
Sponsor:   Vanderbilt University Medical Center
Withdrawn

Mon, 01 Jun 2015 12:00:00 EDT

Helium-3 MRI Imaging Study in COPD

Condition:   Pulmonary Disease, Chronic Obstructive
Interventions:   Device: He-3 MRI;   Drug: Salbutamol;   Drug: Ipratropium;   Device: MRI
Sponsor:   GlaxoSmithKline
Completed

Mon, 04 Aug 2014 12:00:00 EDT

Postmarketing Surveillance Study of Anticholinergics - Prescribing Pattern and Therapeutic Long Term Value in Patients Suffering From Moderate or Severe Chronic Obstructive Pulmonary Disease (COPD)

Condition:   Pulmonary Disease, Chronic Obstructive
Interventions:   Drug: Atrovent®;   Drug: Ventilat®
Sponsor:   Boehringer Ingelheim
Completed

Fri, 12 Sep 2014 12:00:00 EDT

Evaluation of Safety of ZyComb® In Patients With Common Cold - ZIP 3000 (XY-005-IM)

Condition:   Common Cold
Intervention:   Drug: xylometazoline hydrochloride and ipratropium bromide (ZyComb)
Sponsor:   Nycomed
Completed

Wed, 30 May 2007 12:00:00 EDT

Ventilation-drive Coupling to Evaluate The Efficacy of Inhaled Bronchodilators in Patients With COPD

Condition:   Chronic Obstructive Pulmonary Disease (COPD)
Interventions:   Drug: Placebo;   Drug: ipratropium bromide;   Drug: salbutamol
Sponsors:   Zhujiang Hospital;   Guangzhou Panyu Central Hospital
Completed

Thu, 20 Nov 2014 12:00:00 EST

Budesonide Inhalation Suspension for Acute Asthma in Children

Conditions:   Asthma;   Acute Asthma;   Reactive Airway Exacerbation
Interventions:   Drug: Budesonide inhalation suspension (0.5 mg/2mL) 2mg, albuterol (5mg/mL) 7.5 or 10mg;   Drug: Prednisolone, prednisone, or methylprednisolone;   Drug: Albuterol, ipratropium bromide;   Drug: Ipratropium bromide
Sponsor:   Children's Hospital of Philadelphia
Completed

Fri, 27 Oct 2006 12:00:00 EDT

GOLD Stage I Chronic Obstructive Pulmonary Disease (COPD)

Conditions:   Mild Chronic Obstructive Pulmonary Disease;   Respiratory Symptoms;   Physical Activity
Intervention:   Drug: Combination ipratropium/salbutamol or placebo (nebulization)
Sponsors:   Laval University;   Boehringer Ingelheim;   Pfizer
Completed

Thu, 26 May 2011 12:00:00 EDT

Sensitivity of the Step Test to Detect Improvement in Dyspnea Following Bronchodilation in Patients With Chronic Obstructive Pulmonary Disease

Conditions:   Moderate Chronic Obstructive Pulmonary Disease;   Severe Chronic Obstructive Pulmonary Disease;   Dyspnea
Intervention:   Drug: Combination ipratropium/salbutamol or placebo (nebulization)
Sponsors:   Laval University;   Université de Montréal
Unknown status

Wed, 01 Aug 2012 12:00:00 EDT

HandiHaler® vs. Metered Dose Inhaler (MDI) in Patients With Chronic Obstructive Pulmonary Disease (COPD)

Condition:   Pulmonary Disease, Chronic Obstructive
Interventions:   Device: Placebo capsule administered via the HandiHaler®;   Device: Ipratropium metered dose inhaler (MDI)
Sponsor:   Boehringer Ingelheim
Completed

Tue, 24 Jun 2014 12:00:00 EDT

The Effects of RPL554 on Top of Standard COPD Reliever Medications

Condition:   Chronic Obstructive Pulmonary Disease
Interventions:   Drug: Salbutamol;   Drug: Ipratropium;   Drug: RPL554;   Drug: Salbutamol matched placebo;   Drug: Ipratropium matched placebo;   Drug: RPL554 matched placebo
Sponsor:   Verona Pharma plc
Completed

Fri, 04 Sep 2015 12:00:00 EDT

Symbicort in Airway Predominant Chronic Obstructive Pulmonary Disease (COPD)

Condition:   Pulmonary Disease, Chronic Obstructive
Interventions:   Drug: Budesonide;   Drug: budesonide/formoterol;   Drug: Ipratropium/albuterol
Sponsors:   National Jewish Health;   AstraZeneca
Completed

Fri, 03 Dec 2010 12:00:00 EST

A Pilot Study to Determine the Feasibility and Utility of Implementing of the Full Scale TOM Trial

Condition:   Asthma
Interventions:   Drug: Fluticasone 250 mg/salmeterol 50 mg;   Drug: Montelukast 10mg;   Drug: Theophylline 400 mg;   Drug: ipratropium
Sponsors:   University of California, San Diego;   National Heart, Lung, and Blood Institute (NHLBI)
Completed

Fri, 28 Sep 2012 12:00:00 EDT

Efficacy of Formoterol vs Ipatropioum Bromide Plus Fenoterol in Children (5-<12 Years) With Acute Bronchial Obstruction

Condition:   Acute Bronchial Obstruction, Asthma
Interventions:   Drug: Formoterol fumerate;   Drug: fenoterol/ipratropium bromide
Sponsor:   Novartis
Completed

Mon, 16 Apr 2007 12:00:00 EDT

Effectiveness of Antitussives, Anticholinergics and Honey Versus Usual Care in Adults With Acute Bronchitis.

Condition:   Acute Bronchitis
Interventions:   Drug: Dextromethorphan 15 milligrams;   Drug: Ipratropium Bromide 20Micrograms Inhaler;   Dietary Supplement: Honey 30 g (full tablespoon);   Other: Usual clinical practice
Sponsors:   Jordi Gol i Gurina Foundation;   Spanish Clinical Research Network - SCReN
Recruiting

Tue, 13 Nov 2018 12:00:00 EST

A Pilot Comparison Study of Vibrating Mesh Versus Standard Jet Nebuliser for Bronchodilator Delivery in COPD

Condition:   Chronic Obstructive Pulmonary Disease (COPD)
Interventions:   Device: vibrating mesh nebuliser;   Device: Standard hospital jet nebuliser;   Drug: Combined salbutamol 2.5 mg and ipratropium 0.5mg nebule
Sponsors:   Beaumont Hospital;   Aerogen
Completed

Fri, 19 Feb 2016 12:00:00 EST

Replacement of Nebulised Ipratropium With Inhaled Tiotropium in Stable Chronic Obstructive Pulmonary Disease (COPD)

Condition:   Chronic Obstructive Pulmonary Disease
Intervention:   Drug: Inhaled Tiotropium
Sponsor:   NHS Greater Glasgow and Clyde
Withdrawn

Mon, 12 Jun 2006 12:00:00 EDT

The Efficacy and Safety of Salmeterol/Fluticasone Propionate vs Atropium/Albuterol in Patients COPD

Condition:   Chronic Obstructive Pulmonary Disease (COPD)
Intervention:   Drug: Salmeterol/Fluticasone Propionate
Sponsors:   Fudan University;   Shanghai Zhongshan Hospital;   The First Affiliated Hospital of Guangzhou Medical University;   The First Affiliated Hospital with Nanjing Medical University;   Guangzhou First People's Hospital;   Peking Union Medical College Hospital;   Beijing Chao Yang Hospital;   Peking University Third Hospital;   Liaoning Tumor Hospital & Institute;   West China Hospital;   Xinqiao Hospital of Chongqing;   Qingdao University;   Armed Police Medical college Affiliated Hospital;   The First Affiliated Hospital of Anhui Medical University;   Henan Provincial People's Hospital
Unknown status

Fri, 19 Nov 2010 12:00:00 EST

Lung Health Study (LHS) I and III

Conditions:   Lung Diseases;   Lung Diseases, Obstructive;   Chronic Obstructive Pulmonary Disease
Interventions:   Behavioral: smoking cessation;   Drug: ipratropium
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Completed

Thu, 28 Oct 1999 12:00:00 EDT

Influence of Mechanical Ventilation Modes on the Efficacy of Nebulized Bronchodilator

Conditions:   COPD;   Asthma
Interventions:   Drug: salbutamol sulfate and ipratropium bromide;   Device: Mesh nebulization
Sponsor:   Universidade Federal do Rio Grande do Norte
Unknown status

Tue, 05 Sep 2017 12:00:00 EDT

Bronchodilators and Oxygen Kinetics With Exercise in Chronic Obstructive Pulmonary Disease (COPD) Patients

Condition:   Chronic Obstructive Pulmonary Disease
Intervention:   Drug: Combivent
Sponsor:   Queen's University
Completed

Thu, 20 Jul 2006 12:00:00 EDT

Combivent vs. Salbutamol in Patients With Metacholine Induced Bronchospasm

Condition:   Asthma
Interventions:   Drug: Salbutamol sulfate/Ipratropium bromide;   Drug: Salbutamol
Sponsor:   Boehringer Ingelheim
Completed

Tue, 08 Jul 2014 12:00:00 EDT

Effect of Compound Sodium Chlorate and Aminophylline Tablets on Chronic Obstructive Pulmonary Disease(COPD).

Condition:   Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Interventions:   Drug: Compound Ipratropium Bromide Solution(C1) for Inhalation;   Drug: Compound Sodium Chlolate and Aminophylline Tablets(C2);   Drug: Placebo Tablets
Sponsor:   Wuhan Union Hospital, China
Recruiting

Tue, 24 Sep 2019 12:00:00 EDT

Glittre ADL-test: Responsiveness to Acute Bronchodilation in Chronic Obstructive Pulmonary Disease (COPD)

Condition:   Chronic Obstructive Pulmonary Disease
Interventions:   Drug: Bronchodilators;   Drug: Placebos
Sponsors:   Laval University;   Institut Universitaire de Cardiologie et Pneumologie de Québec
Unknown status

Tue, 07 Mar 2017 12:00:00 EST

Respimat® Combivent Trial in Chronic Obstructive Pulmonary Disease (COPD)

Condition:   Pulmonary Disease, Chronic Obstructive
Interventions:   Drug: Atrovent Respimat (20 mcg);   Drug: COMBIVENT MDI (36/206 mcg);   Drug: Combivent Respimat (20 mcg/100 mcg);   Drug: Placebo via corresponding inhaler for blinding purposes
Sponsor:   Boehringer Ingelheim
Completed

Thu, 16 Nov 2006 12:00:00 EST

Effects of TD-4208 on FEV1 in Subjects With Chronic Obstructive Pulmonary Disease (COPD)

Condition:   Chronic Obstructive Pulmonary Disease, COPD
Interventions:   Drug: Placebo;   Drug: TD-4208 700 μg;   Drug: TD-4208 350 μg;   Drug: Ipratropium 500 μg
Sponsors:   Mylan Inc.;   Theravance Biopharma
Completed

Fri, 24 Feb 2017 12:00:00 EST

A Crossover Study in the Treatment of Patients With COPD

Condition:   Chronic Obstructive Pulmonary Disease
Interventions:   Drug: Formoterol Fumurate inhalation solution 20 mcg;   Drug: Ipratropium bromide 18 mcg and albuterol sulfate 103 mcg
Sponsor:   Dey
Completed

Thu, 19 Apr 2007 12:00:00 EDT

Outcomes and Costs Associated With Initiating Maintenance Treatment With Fluticasone Propionate 250mcg/Salmeterol Xinafoate 50mcg Combination (FSC) Versus Anticholinergics Including Tiotropium (TIO) in Patients With Chronic Obstructive Pulmonary Disease (COPD)

Condition:   Pulmonary Disease, Chronic Obstructive
Interventions:   Drug: fluticasone/salmeterol combination (FSC) 250/50mcg;   Drug: tiotropium;   Drug: ipratropium bromide alone or in fixed dose combination with albuterol
Sponsor:   GlaxoSmithKline
Completed

Fri, 08 Apr 2011 12:00:00 EDT

12 Week Comparison of 5 Mcg and 10 Mcg of Tiotropium / Respimat, Placebo and Ipratropium MDI in COPD

Condition:   Pulmonary Disease, Chronic Obstructive
Interventions:   Device: 5 mcg once daily tiotropium inhalation solution delivered by the Respimat inhaler;   Device: 10 mcg once daily tiotropium inhalation solution delivered by the Respimat inhaler
Sponsor:   Boehringer Ingelheim
Completed

Tue, 18 Oct 2005 12:00:00 EDT

12 Week Comparison of 5 Mcg and 10 Mcg of Tiotropium / Respimat, Placebo and Ipratropium MDI in COPD

Condition:   Pulmonary Disease, Chronic Obstructive
Interventions:   Device: 5 mcg once daily tiotropium inhalation solution delivered by the Respimat inhaler;   Device: 10 mcg once daily tiotropium inhalation solution delivered by the Respimat inhaler
Sponsor:   Boehringer Ingelheim
Completed

Mon, 17 Oct 2005 12:00:00 EDT

A Trial Comparing Treatment With Tiotropium Inhalation Capsules to Combivent Inhalation Aerosol in COPD Patients.

Condition:   Pulmonary Disease, Chronic Obstructive
Interventions:   Drug: tiotropium;   Drug: Combivent (Ipratropium/Albuterol)
Sponsor:   Boehringer Ingelheim
Completed

Wed, 02 Aug 2006 12:00:00 EDT

Trial Comparing Treatment With Tiotropium Inhalation Capsules to Combivent® Inhalation Aerosol in COPD Patients.

Condition:   Pulmonary Disease, Chronic Obstructive
Interventions:   Drug: tiotropium;   Drug: ipratropium bromide / albuterol
Sponsor:   Boehringer Ingelheim
Completed

Tue, 17 Oct 2006 12:00:00 EDT

Optimising the Propranolol Block Model

Condition:   Pulmonary Disease, Chronic Obstructive
Interventions:   Drug: Propranolol;   Drug: Salbutamol;   Drug: Ipratropium;   Drug: Placebo
Sponsor:   GlaxoSmithKline
Completed

Thu, 25 Oct 2007 12:00:00 EDT

Effect of Nebulized Bronchodilators on Heart Rate

Conditions:   COPD;   Sepsis;   Shock
Interventions:   Drug: Levalbuterol;   Drug: Albuterol
Sponsors:   Fahim Khorfan, MD;   Ascension Genesys Hospital
Completed

Mon, 28 Jun 2010 12:00:00 EDT

Nebulized Magnesium Sulfate as an Adjunct to Standard Therapy in Asthma Exacerbation

Condition:   Asthma
Interventions:   Drug: Nebulized Magnesium Sulfate;   Drug: Nebulized isotonic saline;   Drug: Nebulized Salbutamol;   Drug: Ipratropium bromide;   Drug: Methylprednisolone or Prednisolone
Sponsor:   Hospital General Naval de Alta Especialidad - Escuela Medico Naval
Unknown status

Fri, 23 Oct 2015 12:00:00 EDT

Study of Budesonide as an Addition to Standard Therapy in Adult Asthmatics in the Emergency Room.

Condition:   Asthma
Interventions:   Drug: Budesonide;   Drug: albuterol;   Drug: Ipratropium bromide;   Drug: Prednisone
Sponsors:   Northwell Health;   AstraZeneca;   Jacobi Medical Center;   Nassau University Medical Center
Completed

Tue, 08 Jan 2008 12:00:00 EST

Safety and Efficacy of Berodual® Respimat® Compared to Berodual® MDI (Metered Dose Inhaler) in Asthma Patients

Condition:   Asthma
Interventions:   Drug: Berodual® via Respimat®, high dose;   Drug: Berodual® via Respimat®, low dose;   Drug: Berodual® via MDI, high dose;   Drug: Placebo Respimat®;   Drug: Placebo MDI
Sponsor:   Boehringer Ingelheim
Completed

Tue, 08 Jul 2014 12:00:00 EDT

Comparison of Safety and Efficacy of Berodual® Administered Via the Respimat® Device With That Administered Via the Metered Dose Inhaler (MDI) in Patients With Chronic Obstructive Pulmonary Disease (COPD)

Condition:   Pulmonary Disease, Chronic Obstructive
Interventions:   Drug: Berodual® Respimat ® high dose;   Drug: Berodual® Respimat ® low dose;   Drug: Berodual® MDI;   Drug: Placebo
Sponsor:   Boehringer Ingelheim
Completed

Wed, 25 Jun 2014 12:00:00 EDT

Safety and Efficacy of Berodual® Inhaled Via Respimat® Compared to MDI (Metered Dose Inhaler) in Pediatric Patients With Asthma

Condition:   Asthma
Interventions:   Drug: Berodual® Respimat®, low dose;   Drug: Berodual® Respimat®, high dose;   Drug: Berodual® MDI
Sponsor:   Boehringer Ingelheim
Completed

Tue, 08 Jul 2014 12:00:00 EDT

Study in Healthy Volunteers and COPD Patients to Evaluate the Efficacy and Safety of Inhaled TV46017

Condition:   Chronic Obstructive Pulmonary Disease (COPD
Interventions:   Drug: TV46017;   Drug: Placebo
Sponsor:   Teva Branded Pharmaceutical Products R&D, Inc.
Terminated

Thu, 11 Dec 2014 12:00:00 EST

An Investigation Of The Interaction Of GSK961081 With Inhaled Beta-Agonist And Anti-Muscarinic Drugs.

Condition:   Pulmonary Disease, Chronic Obstructive
Interventions:   Drug: 400 microgrammes GSK961081;   Drug: 1200 microgrammes GSK961081
Sponsor:   GlaxoSmithKline
Completed

Thu, 08 May 2008 12:00:00 EDT

Study to Investigate the Dose Response, Safety and Efficacy of Nebulized EP-101(SUN101) in Patients With Chronic Obstructive Pulmonary Disease (COPD): GOLDEN-1 Study

Condition:   Chronic Obstructive Pulmonary Disease
Interventions:   Drug: EP-101 via nebulizer (eFlow®) 25 ug;   Drug: EP-101 via nebulizer (eFlow®) 50 ug;   Drug: EP-101 via nebulizer (eFlow®) 100 ug;   Drug: Placebo EP-101;   Drug: Tiotropium bromide via (Spiriva® Handihaler®);   Drug: Ipratropium bromide Inhalation Solution via Handihaler® DPI;   Drug: EP-101 via nebulizer (eFlow®) 200 ug
Sponsor:   Sunovion Respiratory Development Inc.
Completed

Tue, 30 Aug 2011 12:00:00 EDT

Berodual® Respimat® Versus Berodual® Metered Aerosol (MA) Inhaler in Patients With Asthma, Chronic Obstructive Pulmonary Disease, or Mixed Condition

Conditions:   Pulmonary Disease, Chronic Obstructive;   Asthma
Interventions:   Drug: Berodual® Respimat®;   Drug: Berodual® MA HFA
Sponsor:   Boehringer Ingelheim
Completed

Wed, 25 Jun 2014 12:00:00 EDT

Risk of Re-Hospitalization in Patients With Chronic Obstructive Pulmonary Disease (COPD) Post Exacerbation

Condition:   Pulmonary Disease, Chronic Obstructive
Interventions:   Drug: FSC;   Drug: ACs
Sponsor:   GlaxoSmithKline
Completed

Mon, 27 Jun 2011 12:00:00 EDT

Berodual® Respimat® vs Metered Dose Inhaler in Patients With Chronic Obstructive Pulmonary Disease

Condition:   Pulmonary Disease, Chronic Obstructive
Interventions:   Drug: Berodual® Respimat® inhaler;   Drug: Berodual® metered dose inhaler
Sponsor:   Boehringer Ingelheim
Terminated

Fri, 27 Jun 2014 12:00:00 EDT

Chronic Obstructive Pulmonary Disease (COPD)-Related Outcomes and Costs for Patients on Combination Fluticasone Propionate-Salmeterol Xinafoate 250/50mcg Versus Anticholinergics in a COPD-Comorbid Depression/Anxiety Population

Condition:   Pulmonary Disease, Chronic Obstructive
Interventions:   Drug: fluticasone propionate/salmeterol xinafoate;   Drug: Anticholinergics
Sponsor:   GlaxoSmithKline
Completed

Mon, 18 Apr 2011 12:00:00 EDT

Nebulizer Versus Dry Powdered Inhalers for Chronic Obstructive Pulmonary Disease (COPD)

Conditions:   COPD;   COPD Exacerbation
Interventions:   Device: Nebulizers;   Device: Dry Powder Inhaler;   Drug: Brovana;   Drug: Pulmicort;   Drug: Atrovent;   Drug: Advair Diskus;   Drug: Spiriva HandiHaler
Sponsor:   Wake Forest University Health Sciences
Terminated

Tue, 18 Jul 2017 12:00:00 EDT

Mechanisms of Adverse Effects of Long-Acting Beta-Agonists in Asthma

Condition:   Asthma
Interventions:   Drug: Salmeterol Xinafoate;   Drug: Salmeterol Fluticasone
Sponsors:   Imperial College London;   European Research Council
Not yet recruiting

Fri, 07 Aug 2020 12:00:00 EDT

The Use of Inhaled Corticosteroids in the Treatment of Asthma is Children in the Emergency Room

Condition:   Status Asthmaticus
Interventions:   Drug: Budesonide;   Drug: Normal saline
Sponsors:   King Saud University;   King Fahad Medical City
Completed

Wed, 01 Feb 2012 12:00:00 EST

Salbutamol in the Pediatric Emergencies: Nebulization Estimated Via AerogeN or Jet

Condition:   Asthma
Interventions:   Device: vibrating Mesh nebulizer;   Device: jet nebulizer
Sponsor:   Centre d'Investigation Clinique et Technologique 805
Unknown status

Fri, 03 Feb 2017 12:00:00 EST

Non-invasive Ventilation vs. Standard Therapy for Children Hospitalized With an Acute Exacerbation of Asthma

Conditions:   Asthma Acute;   Asthma in Children
Interventions:   Device: BiPAP;   Device: CPAP;   Drug: Ipratropium;   Drug: Magnesium Sulfate;   Drug: Aminophylline;   Drug: Standard steroid dose, hourly salbutamol, oxygen as needed
Sponsors:   University of British Columbia;   Post Graduate Institute of Medical Education and Research, Chandigarh
Unknown status

Thu, 28 Sep 2017 12:00:00 EDT

An Efficacy and Safety Profile of Inhaled TV48108 in Healthy Volunteers and COPD Patients

Condition:   Chronic Obstructive Pulmonary Disease
Interventions:   Drug: TV48108;   Drug: Placebo
Sponsor:   Teva Branded Pharmaceutical Products R&D, Inc.
Terminated

Thu, 11 Dec 2014 12:00:00 EST

Outcomes for Chronic Obstructive Pulmonary Disease Moderate Exacerbators Initiating Treatment

Condition:   Pulmonary Disease, Chronic Obstructive
Interventions:   Drug: Fluticasone Propionate / Salmeterol Xinafoate Combination (FSC);   Drug: Anticholinergics (AC)
Sponsor:   GlaxoSmithKline
Completed

Mon, 18 Jul 2011 12:00:00 EDT

Effectiveness of the Aeroneb in Acute Severe Asthma

Condition:   Asthma Exacerbation
Interventions:   Device: Aeroneb nebulizer;   Device: Small volume jet nebulizer
Sponsor:   Tufts Medical Center
Completed

Tue, 24 Jan 2017 12:00:00 EST

Safety and Tolerability of COMBIVENT® HFA as Compared to COMBIVENT® CFC and Placebo HFA in Healthy Male and Female Subjects

Condition:   Healthy
Interventions:   Drug: COMBIVENT® HFA-MDI;   Drug: COMBIVENT® CFC-MDI;   Drug: Placebo HFA-MDI
Sponsor:   Boehringer Ingelheim
Completed

Wed, 25 Jun 2014 12:00:00 EDT

Aridol Challenge as a Tool to Predict Treatment Response to Inhaled Corticosteroids in COPD

Condition:   Lung Diseases, Obstructive
Interventions:   Drug: Dry powder mannitol;   Drug: Budesonide 400mcg administered via turbuhaler;   Drug: Ipratropium bromide 80mcg;   Drug: Salbutamol 400mcg
Sponsor:   Pharmaxis
Completed

Mon, 04 Jul 2005 12:00:00 EDT

Nebulized Magnesium Sulfate in Pediatric Asthma

Condition:   Asthma
Interventions:   Drug: Nebulized Magnesium Sulfate;   Other: Nebulized normal saline
Sponsor:   Children's Hospital Medical Center, Cincinnati
Withdrawn

Wed, 29 Aug 2007 12:00:00 EDT

Differential Mechanisms of Dyspnea Relief in Advanced COPD: Opiates vs. Bronchodilators

Condition:   Chronic Obstructive Pulmonary Disease
Interventions:   Drug: Fentanyl Citrate;   Drug: Combivent
Sponsors:   Queen's University;   Ontario Lung Association
Suspended

Fri, 19 Jan 2018 12:00:00 EST

Assessment of Reactance Parameters Measured by the Forced Oscillation Technique for the Bronchodilator Response in Subjects With Chronic Obstructive Pulmonary Disease (COPD)

Condition:   Chronic Obstructive Pulmonary Disease
Intervention:   Drug: Duovent HFA
Sponsor:   Centre Hospitalier Universitaire Dinant Godinne - UCL Namur
Not yet recruiting

Wed, 10 Apr 2019 12:00:00 EDT

Postmarketing Surveillance Study of Berodual® Metered-dose Inhaler in Chronic Obstructive Respiratory Tract Disease

Condition:   Pulmonary Disease, Chronic Obstructive
Intervention:   Drug: Berodual®
Sponsor:   Boehringer Ingelheim
Completed

Fri, 05 Sep 2014 12:00:00 EDT

Post-marketing Surveillance of Berodual® Metered-dose Inhaler in the Treatment of Chronic Obstructive Respiratory Tract Disease

Condition:   Pulmonary Disease, Chronic Obstructive
Intervention:   Drug: Berodual®
Sponsor:   Boehringer Ingelheim
Completed

Thu, 04 Sep 2014 12:00:00 EDT

Postmarketing Surveillance Study of Berodual® Metered-dose Inhaler in Chronic Obstructive Airways Disease

Condition:   Pulmonary Disease, Chronic Obstructive
Intervention:   Drug: Drug: Berodual®
Sponsor:   Boehringer Ingelheim
Completed

Thu, 04 Sep 2014 12:00:00 EDT

Berodual® Respimat® Solution for Inhalation in Patients With Chronic Obstructive Airways Disease

Condition:   Pulmonary Disease, Chronic Obstructive
Intervention:   Drug: Berodual® Respimat® solution for inhalation
Sponsor:   Boehringer Ingelheim
Completed

Thu, 04 Sep 2014 12:00:00 EDT

Berodual® Respimat® Solution for Inhalation in Patients With Chronic Obstructive Airways Disease

Condition:   Pulmonary Disease, Chronic Obstructive
Intervention:   Drug: Berodual® Respimat® solution for inhalation
Sponsor:   Boehringer Ingelheim
Completed

Thu, 04 Sep 2014 12:00:00 EDT

Postmarketing Surveillance Study to Assess Handling and Patient Satisfaction on Berodual® Respimat® Solution for Inhalation in Comparison to a Powder Inhaler in Patients With Chronic Obstructive Pulmonary Disease

Condition:   Pulmonary Disease, Chronic Obstructive
Intervention:   Drug: Berodual® Respimat® - inhaler
Sponsor:   Boehringer Ingelheim
Completed

Thu, 04 Sep 2014 12:00:00 EDT

Postmarketing Surveillance Study to Assess Handling and Patient Satisfaction on Berodual® Respimat® Solution for Inhalation in Patients With Chronic Obstructive Pulmonary Disease

Condition:   Pulmonary Disease, Chronic Obstructive
Intervention:   Drug: Berodual® Respimat® - inhaler
Sponsor:   Boehringer Ingelheim
Completed

Thu, 04 Sep 2014 12:00:00 EDT

Chronic Obstructive Pulmonary Disease (COPD)-Related Healthcare Utilization and Costs After Discharge From a Hospitalization or Emergency Department Visit on a Regimen of Fluticasone Propionate-Salmeterol Combination Versus Other Maintenance Therapies

Condition:   Pulmonary Disease, Chronic Obstructive
Interventions:   Drug: fluticasone propionate/salmeterol xinafoate combination;   Drug: Other maintenance Treatments (OMT)
Sponsor:   GlaxoSmithKline
Completed

Mon, 11 Apr 2011 12:00:00 EDT

Aerosol Therapy in Obese COPD Patients.

Conditions:   Chronic Obstructive Pulmonary Disease Moderate;   Obesity
Interventions:   Radiation: inhalation protocol;   Device: High Flow Nasal Cannula
Sponsor:   Universidade Federal do Rio Grande do Norte
Completed

Wed, 25 Jan 2017 12:00:00 EST

Respimat® Inhaler vs a Metered Dose Inhaler Using Berodual® in Patients With Chronic Obstructive Pulmonary Disease (COPD)

Condition:   Pulmonary Disease, Chronic Obstructive
Interventions:   Drug: Berodual® Respimat®, low inspiratory flow rate;   Drug: Berodual® Respimat®, medium inspiratory flow rate;   Drug: Berodual® Respimat®, high inspiratory flow rate;   Drug: Berodual® HFA-MDI, low inspiratory flow rate;   Drug: Berodual® HFA-MDI, medium inspiratory flow rate;   Drug: Berodual® HFA-MDI, high inspiratory flow rate
Sponsor:   Boehringer Ingelheim
Terminated

Fri, 27 Jun 2014 12:00:00 EDT

Evaluation of the Respimat Inhaler vs. a HFA MDI Using Berodual in Patients With COPD With Poor MDI Technique.

Conditions:   Pulmonary Disease, Chronic Obstructive;   Asthma
Interventions:   Device: Berodual Respimat;   Device: Berodual HFA-MDI
Sponsor:   Boehringer Ingelheim
Completed

Thu, 22 Dec 2005 12:00:00 EST

Flow Rate Effect Respimat Inhaler Versus a Metered Dose Inhaler Using Berodual in Patients With Chronic Obstructive Pulmonary Disease (COPD)

Conditions:   Pulmonary Disease, Chronic Obstructive;   Asthma
Interventions:   Device: Berodual Respimat;   Device: Berodual HFA-MDI
Sponsor:   Boehringer Ingelheim
Completed

Mon, 12 Sep 2005 12:00:00 EDT

Efficacy of Nebulized Pulmicort Respules in Primary Lung Cancer Patients With COPD

Conditions:   Post Operative Complication, Pulmonary;   Lung Cancer;   COPD
Intervention:   Drug: Budesonide
Sponsor:   Xiuyi Zhi
Unknown status

Wed, 22 Jul 2015 12:00:00 EDT

Borg Score Outcomes in Respiratory Compromised Acute Exacerbating Chronic Obstructive Pulmonary Disease (COPD) Patients Receiving Treatment Via Vibrating Mesh Nebuliser Versus Jet Nebuliser in the Emergency Department

Conditions:   COPD Exacerbation;   COPD
Interventions:   Device: Jet Nebuliser;   Device: Vibrating Mesh Nebuliser
Sponsors:   NHS Greater Clyde and Glasgow;   Aerogen
Recruiting

Fri, 29 Nov 2019 12:00:00 EST

Radioaerosol Pulmonary Deposition During Asthma Exacerbation Through Noninvasive Ventilation

Condition:   Asthma
Interventions:   Device: NV;   Other: NEB group
Sponsors:   Universidade Federal de Pernambuco;   Coordenação de Aperfeiçoamento de Pessoal de Nível Superior.
Completed

Wed, 11 Nov 2009 12:00:00 EST

Medicated Aerosol Delivery Using A Jet Nebulizer Versus A Vibrating Mesh Nebulizer in COPD Exacerbation

Condition:   Chronic Obstructive Pulmonary Disease
Interventions:   Device: Vibrating Mesh Nebulizer;   Device: Jet Nebulizer
Sponsor:   Medstar Health Research Institute
Unknown status

Tue, 14 Feb 2017 12:00:00 EST

Effectiveness of Vibrating Mesh Versus Small Volume Nebuliser in Chronic Obstructive Pulmonary Disease (COPD)

Conditions:   Chronic Obstructive Pulmonary Disease;   COPD;   Copd Exacerbation Acute;   COPD Exacerbation
Interventions:   Device: Vibrating Mesh Nebuliser;   Device: Standard Hospital Care
Sponsors:   Beaumont Hospital;   Aerogen
Completed

Tue, 19 Sep 2017 12:00:00 EDT

Search of a Paradoxical Fall in Maximum Expiratory Flow After Bronchodilation in Healthy Subjects

Condition:   Paradoxical Fall in Maximum Expiratory Flows
Intervention:   Drug: Inhaled Bronchodilators +/- Inhaled Methacholine
Sponsor:   Assistance Publique - Hôpitaux de Paris
Unknown status

Fri, 24 Feb 2017 12:00:00 EST

Effects of Advair® in Outpatients With Chronic Obstructive Pulmonary Disease (COPD) Acute Exacerbation

Condition:   Chronic Obstructive Pulmonary Disease (COPD)
Interventions:   Drug: prednisone group;   Drug: Advair group
Sponsors:   Laval University;   GlaxoSmithKline
Completed

Wed, 19 Sep 2007 12:00:00 EDT

Breath-Actuated Nebulizer Versus Conventional Continuous-Output Nebulizer in Pediatric Asthma Patients

Condition:   Asthma
Intervention:   Device: Nebulizer (breath-actuated versus conventional continuous-output)
Sponsor:   University Hospitals Cleveland Medical Center
Terminated

Fri, 08 Jan 2010 12:00:00 EST

High-resolution Computed Tomography (HRCT) Evaluation of Airway Distensibility in Lung Transplant Recipients

Condition:   Unspecified Complication of Lung Transplant
Intervention:  
Sponsor:   The University of Texas Medical Branch, Galveston
Completed

Wed, 02 Jan 2008 12:00:00 EST

Non Invasive Positive Pressure Ventilation in Status Asthmaticus

Condition:   Status Asthmaticus
Intervention:   Other: Noninvasive positive pressure ventilation
Sponsor:   Southern Illinois University
Withdrawn

Wed, 27 Jul 2011 12:00:00 EDT

Determinants Of Oral Corticosteroid Responsiveness in Wheezing Asthmatic Youth

Condition:   Asthma
Intervention:  
Sponsors:   St. Justine's Hospital;   Canadian Institutes of Health Research (CIHR)
Completed

Tue, 17 Dec 2013 12:00:00 EST

Mechanism(s)of Airflow Limitation in Moderate-severe Persistent Asthma

Condition:   Asthma
Interventions:   Drug: budesonide/formoterol;   Drug: fluticasone/salmeterol;   Drug: mometasone/formoterol;   Drug: Prednisone
Sponsor:   Gelb, Arthur F., M.D.
Recruiting

Tue, 18 Dec 2007 12:00:00 EST

Randomized Controlled Study on T-PEP Versus IPV Method for Lower Respiratory Airways Clearance in Tetraplegic Tracheotomized Spinal Cord Injured Patients

Condition:   Spinal Cord Injury Cervical
Interventions:   Procedure: T-PEP;   Procedure: IPV
Sponsor:   Montecatone Rehabilitation Institute S.p.A.
Not yet recruiting

Tue, 29 Oct 2019 12:00:00 EDT

Investigation of Intravenous (IV) Administration of an Approved Drug (MK-0476, Montelukast Sodium) for Acute Asthma (MK-0476-288)

Condition:   Asthma
Interventions:   Drug: montelukast sodium;   Drug: placebo
Sponsor:   Merck Sharp & Dohme Corp.
Completed

Wed, 29 Sep 2004 12:00:00 EDT

Safety and Efficacy of Propranolol in Newborns With Retinopathy of Prematurity

Condition:   Retinopathy of Prematurity
Intervention:   Drug: Propranolol
Sponsors:   Azienda Ospedaliero, Universitaria Meyer;   Ospedale Maggiore Policlinico Mangiagalli e Regina Elena
Completed

Wed, 03 Mar 2010 12:00:00 EST

Hemodynamics and Extravascular Lung Water in Acute Lung Injury

Condition:   Acute Lung Injury
Interventions:   Drug: Diuresis (furosemide) part I;   Other: Fluid Bolus (crystalloid or albumin);   Drug: Vasopressors (Norepinephrine, Vasopressin, Phenylephrine, Epinephrine);   Drug: Dobutamine;   Other: Concentrate all drips and nutrition;   Drug: Diuresis (furosemide) part II;   Procedure: Dialysis
Sponsors:   Oregon Health and Science University;   Pulsion Medical Systems;   Oregon Clinical and Translational Research Institute
Completed

Wed, 27 Feb 2008 12:00:00 EST

Nebulized Budesonide Combined With Systemic Corticosteroid in Acute Severe Asthma

Condition:   Acute Asthma
Interventions:   Drug: Budesonide;   Drug: normal saline
Sponsor:   University of Monastir
Unknown status

Thu, 11 Jul 2019 12:00:00 EDT

COPD AND ASSESSMENT OF RADIOLABELED AEROSOL DURING NONINVASIVE VENTILATION

Condition:   COPD
Interventions:   Other: Noninvasive ventilation;   Device: Jet Nebulizer;   Device: Vibrating Mesh Nebulizer (VMN)
Sponsors:   Daniella Cunha Brandao;   Universidade Federal de Pernambuco
Completed

Thu, 25 Sep 2014 12:00:00 EDT

Asthma and Quantifying Delivery Of Radio Labeled Aerosol

Condition:   Asthma
Interventions:   Other: Noninvasive ventilation;   Device: Jet nebulizer;   Device: The vibrating mesh nebulizer (VMN)
Sponsor:   Universidade Federal de Pernambuco
Completed

Thu, 04 Apr 2013 12:00:00 EDT

a Prospective Cohort Study for Propranolol Treatment in Retinopathy of Prematurity

Condition:   Retinopathy of Prematurity
Interventions:   Drug: Propranolol;   Drug: placebo
Sponsor:   Guangdong Women and Children Hospital
Unknown status

Tue, 31 Jan 2017 12:00:00 EST

NiPPV in the Treatment of Acute Asthma Exacerbations

Conditions:   Bronchial Asthma;   Status Asthmaticus
Interventions:   Procedure: Standard of Care therapies;   Device: NiPPV Therapy;   Procedure: Routine Respiratory Care
Sponsor:   Arkansas Children's Hospital Research Institute
Withdrawn

Mon, 17 Jul 2017 12:00:00 EDT

Radioaerossol Pulmonary Deposition Using Mesh in Normal Subjects

Condition:   Normal Subjects
Interventions:   Other: Mesh nebulizer;   Other: Jet nebulizer;   Other: Noninvasive ventilation-NIV
Sponsors:   Universidade Federal de Pernambuco;   Georgia State University;   Coordenação de Aperfeiçoamento de Pessoal de Nível Superior.;   Conselho Nacional de Desenvolvimento Científico e Tecnológico
Completed

Fri, 28 Jun 2013 12:00:00 EDT

Reversal of Acute β-Blocker Induced Bronchoconstriction

Condition:   Asthma
Intervention:   Drug: Hydrocortisone/ Placebo and Propranolol
Sponsors:   University of Dundee;   NHS Tayside
Completed

Wed, 17 Feb 2010 12:00:00 EST

Physiotherapy in Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Condition:   COPD
Interventions:   Other: Physiotherapy program;   Drug: Medical standard treatment
Sponsor:   Universidad de Granada
Unknown status

Tue, 04 Aug 2015 12:00:00 EDT

LTOT in COPD Patients With Moderate Chronic Hypoxemia and Chronic Heart Failure

Conditions:   Lung Diseases, Obstructive;   Chronic Heart Failure;   Chronic Hypoxemia
Interventions:   Other: LTOT (oxygen therapy);   Other: Pharmacological therapy of COPD and CHF
Sponsors:   Azienda Ospedaliero-Universitaria Careggi;   University of Modena and Reggio Emilia
Unknown status

Tue, 29 Apr 2008 12:00:00 EDT

High Flow Nasal Cannula in Children With Status Asthmaticus

Condition:   Status Asthmaticus
Interventions:   Device: HFNC;   Device: Standard Oxygen Treatment
Sponsor:   Hospices Civils de Lyon
Recruiting

Wed, 17 May 2017 12:00:00 EDT

Pharmacogenetics of b2-Agonists in Asthma.

Condition:   Asthma
Intervention:  
Sponsors:   Nemours Children's Clinic;   University of Florida;   National Heart, Lung, and Blood Institute (NHLBI)
Completed

Wed, 02 Jul 2008 12:00:00 EDT

Effect of Physiotherapy in Hospitalized COPD Patients

Condition:   COPD
Interventions:   Other: Physiotherapy program 1;   Other: Physiotherapy program 2;   Drug: Standard medical treatment
Sponsor:   Universidad de Granada
Completed

Tue, 28 Jul 2015 12:00:00 EDT

A Pilot Study of Danirixin for Disease Progression in Chronic Obstructive Pulmonary Disease (COPD)

Condition:   Pulmonary Disease, Chronic Obstructive
Interventions:   Drug: Danirixin 35 mg tablets;   Drug: Placebo;   Device: Metered dose inhaler (MDI) sensor device;   Drug: Rescue medication
Sponsor:   GlaxoSmithKline
Terminated

Tue, 30 May 2017 12:00:00 EDT

Heliox and Posture in Patients With Asthma

Condition:   Acute Asthma
Interventions:   Other: HELIOX;   Other: OXYGEN;   Other: HELIOX+POSTURE;   Other: OXYGEN + POSTURE
Sponsor:   Universidade Federal de Pernambuco
Completed

Wed, 17 Jun 2009 12:00:00 EDT

Effect of Home-base Exercise With Conical-PEP Device on Physical Performance and Quality of Life in COPD

Condition:   Chronic Obstructive Pulmonary Disease
Interventions:   Device: A non-re-breathing face mask with conical-PEP device;   Other: A home-base exercise program;   Other: Health education;   Other: ฺBreathing strategies for self secretion clearance;   Drug: The medication following the COPD GOLD guidelines (2015)
Sponsors:   Khon Kaen University;   Thailand Research Fund
Unknown status

Fri, 03 Jun 2016 12:00:00 EDT