ITP: Symptoms, Causes, Diagnosis and Treatment

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idiopathic thrombocytopenne purple (ITP), also called purple immune thrombocytopes, is a condition in which the body does not have a sufficient number of platelets .This condition is characterized by purple, which are purple tires on the skin.

ITP is considered an autoimmune disorder , which occurs when the body destroys its own platelets.The condition takes place from about 50 to 150 people per million each year. Around half of those who affected children. The PTP for adults affects women more often than men.

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Symptoms

ITP often does not cause any negative symptoms that a person can have several episodes Syntomatic Yno.You can experience any effect between episodes.

This condition can start suddenly in children or adult bleeding problems. You can notice the inexplicable bruises on your body or bleeding of the nose or mouth.

The Symptoms of ITP may include:

  • bruises can occur after smaller cones or without visible causes.
  • Peteciae, which are small reddish -pulating points, can open on the skin on clusters.They tend to appear on the lower legs and may resemble the eruption.
  • Cuts to stop bleeding.
  • Nasal films or bleeding of the gums can occur.
  • The blood can appear in the urine or in the intestinal movements.
  • Women can have heavy menstrual bleeding.

ITP types

There are two main types of ITP, and differ in the duration of the Illness and age that affect groups.

  • Acute ITP is the temporary type of ITP. It lasts less than six months.This is the most common type of ITP and occurs mainly in children and hands of children from 2 to 4 years. This often happens after the child has an infection or sick with a virus.Children with acute PTP are usually developing Petushiae on the legs and stomach and, as a rule, are fully improved after the episode.
  • chronic ITP In the long term, generally causing symptoms for six months or more that refusal affects adults, but sometimes adolescents or children can develop it.They are more likely to have problems associated with bleeding in the mouth or in a chair.

Complications

In some situations, severe bleeding can occur with ITP.This can lead to a serious blood or harmful bleeding in the brain, lungs or kidneys.

Call

Thrombocytopenia means low blood platelets.Platelets are blood cells that help you prevent bleeding. Adhere to each other and proteins form clots that compact the wounds and cuts.

When your platelet level is low, the wounds may not be wrapped as fast as they should.It can be easily blown, since small blows can cause bleeding under the skin for a long time. Vegeta: These are small bleeding, which occur when capillaries are produced (small blood vessels).They tend to form each other in small or large groups.

The fragile nose and mouth can be easily bleeding. ITP, your internal organ, like a bladder, lungs, stomach or intestines, can also bleed.

idiopathic

The condition is described as idiopathic, because unknown, why some people are developing ITP.This is not hereditary, and there are no important causes of medical care, which makes a person more predisposed to condition.

There are some factors that tend to have a trend that tend to accelerate the PTP , but a conscious acute PTP.But an adult or a child can develop ITP effects without any trigger.

Factors that are often preceded by ITP symptoms include:

ITP automation

ITP is usually caused by an autoimmune response, in which the body attacks its own platelets.The antibodies are proteins that are fighting, but they can attack and destroy their own human tissue. In ITP, an autoimmune reaction leads to a low platelet level.

Diagnostics

ITP diagnoses are carried out using a combination of methods. If you have symptoms, your health care provider will discuss your illness with you.It also has a physical examination that includes the examination of your skin, heart and lungs.

Blood analysis

You probably have blood diagnostic tests as part of your evaluation.Blood tests include Cline A (CBC) combat levels and electrolyte levels. CBC provides platelet counter. As a general rule, in the low number of platelet PTP in ITP.

Left blood (WBC), erythrocytes (RBC) and electrolyte levels are usually normal in ITP.

Smallet

Your medical team may also want to see your platelets under a microscope with blood smear.The blood used to rub on the blood is obtained with the same process as the regular blood sample used for the CBC.B ITP platelets has a normal shape and an appearance in the blood smear.

Your medical team can also see your BMBC and RBC under a microscope. This test can help estimate whether it may have another cause of excessive bruisingsuss, since leukemia or lymphomaklich are leukocyte cancer tiles.

Treatment

Most children with acute ITP type are fully restored in approximately six months without treatment. Adults with soft ITP can not be treated either.

The management of the chronic ITP focuses on increasing the number of blood platelets. There are several different approaches for treatment.

Methods of medical treatment

Many medical procedures used to control the PIP are anti-inflammatory medications that reduce the autoimmune body. Attack against platelets.These medications are commonly used for several months or weeks at the same time.

corticosteroids Like prednisone can be taken for several weeks or months to reduce inflammation.Azatioprine and are immunosuppressants that were used to reduce inflammation in autoimmune diseases in the ITP.

Wincristine is chemotherapeutic medicine, often used for the treatment of blood cancer, such as leukemia, and was also used in the treatment of ITP.New medications, Promact (Eltromopag) and NPort (Romaplostim) can help adjust platelet production to improve the number of platelets in ITP.

There are several procedures that can be used to increase platelet levels in ITP.

Intravenous immunoglobulin (IVIG) is a treatment that includes an antibody injection.This is generally driven intravenously (through the needle in Vienna) or intramuscular injection (IM). You may need several immunogulin sessions for ITP treatment.This treatment has an anti-inflammatory effect, which reduces the autoimmune attack on platelets to increase the number of platelets in ITP.

A splenectomy , which is a surgical removal of the spleen, can reduce the immune function of the body.This approach can improve the amount of platelets in ITP. However, it may have a higher risk of developing infections if you have a spleen.

In situations, when you have a strong bleeding, you can get a transfusion plate .Donor platelets from a bloody bank can be introduced intravenously into your blood to temporarily increase the number of platelets in your body.

Word reception Message of Meds

If you or your child develop inexplicable bruises or bleeding, it is important to get attention Medical. There are a number of diseases that can cause bleeding and bruising problems.If ITP is a diagnosis, the result can be good. Sometimes, treatment for prevention or complications may be required.

Even if you take medications for your status, or if your condition seems to improve some time to get fast care if the symptoms start again.

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