Clinical Trials

Intranasal Ketorolac Tromethamine (Sprix) for Acute Pain of Interstitial Cystitis Flare of Pain

Condition:   Interstitial Cystitis
Intervention:   Drug: Ketorolac Tromethamine
Sponsor:   Citrus Valley Medical Research, Inc.
Completed

Wed, 04 Dec 2013 12:00:00 EST

Pharmacokinetics, Safety, and Efficacy of SPRIX in 12 to 17 Year Old Patients vs. Adult Patients Undergoing Open Surgical Procedures

Condition:   Pain
Intervention:   Drug: SPRIX
Sponsor:   American Regent, Inc.
Completed

Wed, 27 Mar 2013 12:00:00 EDT

Intranasal Ketorolac Tromethamine (SPRIX) as a Short Term Pain Management of Post-Vasectomy Pain

Condition:   Post Vasectomy Pain
Interventions:   Drug: Ketorolac Tromethamine;   Other: Standard of Care
Sponsor:   Citrus Valley Medical Research, Inc.
Unknown status

Wed, 04 Dec 2013 12:00:00 EST

The Pharmacokinetics of Ketorolac Tromethamine Administered Intranasally (IN) for Postoperative Pain in Children Aged 12 Through 17 Years

Condition:   Postoperative Pain
Intervention:   Drug: Ketorolac Tromethamine
Sponsor:   Egalet Ltd
Completed

Wed, 01 Jun 2011 12:00:00 EDT

Efficient Study of ACULAR in Inhibiting Proliferative Retinopathy in Prematurity

Conditions:   Retinopathy of Prematurity;   Retinal Detachment;   Blindness
Interventions:   Drug: ACULAR;   Drug: REFRESH TEARS;   Drug: placebo
Sponsor:   University of South Alabama
Terminated

Thu, 13 Mar 2008 12:00:00 EDT

Toradol to Reduce Ureteroscopic Symptoms Trial

Conditions:   Urinary Lithiasis;   Kidney Diseases;   Kidney Stone;   Pain, Postoperative
Intervention:   Drug: Toradol
Sponsor:   Yale University
Completed

Wed, 12 Apr 2017 12:00:00 EDT

Artificial Tears Versus Preservative Free Ketorolac Trometamol 0.45% for Acute Viral Conjunctivitis

Condition:   Conjunctivitis, Viral
Interventions:   Drug: Ketorolac trometamol 0.45% with carboxymethylcellulose;   Drug: Preservative free artificial tear
Sponsor:   Fundação Altino Ventura
Completed

Wed, 27 Feb 2013 12:00:00 EST

Toradol (Ketorolac) in Breast Surgery to Reduce Pain & Opioid Use

Conditions:   Breast Reduction;   Breast Reconstruction
Interventions:   Drug: Ketorolac Tromethamine;   Other: Saline
Sponsor:   Carilion Clinic
Recruiting

Fri, 19 Jun 2020 12:00:00 EDT

Study to Determine the Tolerability, Safety and Pharmacokinetics of Ketorolac Tromethamine by Intranasal Administration in Healthy Volunteers

Condition:   Healthy Volunteers
Intervention:   Drug: Ketorolac tromethamine
Sponsor:   Egalet Ltd
Completed

Wed, 01 Jun 2011 12:00:00 EDT

Study of the Tolerability of Ketorolac Tromethamine Following Intranasal Administration in Healthy Volunteers

Condition:   Healthy Volunteers
Intervention:   Drug: Ketorolac tromethamine
Sponsor:   Egalet Ltd
Completed

Wed, 01 Jun 2011 12:00:00 EDT

Comparing Acular LS and Pred Forte in Reducing Post-selective Laser Trabeculoplasty Anterior Chamber Flare and Cells

Condition:   Open Angle Glaucoma
Interventions:   Drug: Acular LS;   Drug: Pred Forte;   Other: Refresh Tears
Sponsor:   University of Colorado, Denver
Terminated

Thu, 24 May 2007 12:00:00 EDT

SPRIX in 0 to 11 Year-Old Patients Undergoing Open Surgical Procedures

Condition:   Pain
Intervention:   Drug: SPRIX(intranasal ketorolac tromethamine)
Sponsor:   Egalet Ltd
Completed

Thu, 03 Apr 2014 12:00:00 EDT

A Trial to Assess the Pain-control Efficacy of Intra-articular Toradol Compared to Oral NSAIDs

Condition:   Arthritic Knee Pain
Interventions:   Drug: Toradol;   Drug: Oral NSAID
Sponsor:   The University of Texas Health Science Center, Houston
Withdrawn

Thu, 17 Nov 2016 12:00:00 EST

Prophylactic Effect of Ketorolac Tromethamine on the Cystoid Macular Edema After Phacoemulsification in Diabetic Patients

Condition:   Cystoid Macular Edema After Phacoemulsification
Intervention:   Drug: using of Ketorolac Tromethamine Eye Drop
Sponsor:   Shahid Beheshti University of Medical Sciences
Unknown status

Mon, 11 Jun 2018 12:00:00 EDT

Sprix for Postoperative Pain Control Following Gynecologic Surgery

Conditions:   Post Operative Pain Control;   Narcotic Use;   Pelvic Organ Prolapse;   Urinary Incontinence , Stress;   Surgery
Intervention:   Drug: Sprix
Sponsor:   University of Louisville
Not yet recruiting

Wed, 24 Jun 2020 12:00:00 EDT

Comparison of Topical Ketorolac 0,4% Versus Placebo in Cataract Surgery

Condition:   Cystoid Macular Edema Following Cataract Surgery, Bilateral
Intervention:   Drug: Ketorolac Tromethamine
Sponsor:   University of Campinas, Brazil
Completed

Fri, 02 Mar 2012 12:00:00 EST

Pain Outcomes of Intra-operative IV Tylenol and/or IV Toradol for Carpal Tunnel and Distal Radius Fracture Surgeries

Conditions:   Postoperative Pain;   Carpal Tunnel Release;   Distal Radius Fracture
Interventions:   Drug: Acetaminophen;   Drug: Ketorolac Tromethamine;   Drug: Saline
Sponsor:   John Fowler
Completed

Wed, 10 Dec 2014 12:00:00 EST

Ketorolac Use in Pediatric Patients Undergoing Tonsillectomy

Condition:   Analgesic Adverse Reaction
Interventions:   Drug: Ketorolac Tromethamine;   Drug: 0.9% Normal Saline
Sponsor:   Albany Medical College
Recruiting

Mon, 05 Mar 2018 12:00:00 EST

Open Label Study to Assess the Pharmacokinetics of Intranasal Ketorolac Tromethamine Following Fluticasone Propionate in Healthy Subjects

Condition:   Healthy Subjects
Interventions:   Drug: Ketorolac tromethamine;   Drug: Fluticasone Propionate
Sponsor:   Egalet Ltd
Completed

Fri, 03 Jun 2011 12:00:00 EDT

Study to Assess the PK of Ketorolac Tromethamine Intranasal and to Assess the Effects of a Oxymetazoline Hydrochloride on the PK of Ketorolac Tromethamine

Condition:   Assess Pharmacokinetics of Ketorolac Tromethamine Intranasal and Assess Effects of a Oxymetazoline Hydrochloride on the PK of Ketorolac Tromethamine
Interventions:   Drug: Ketorolac tromethamine;   Drug: Oxymetazoline hydrochloride
Sponsor:   Egalet Ltd
Completed

Wed, 01 Jun 2011 12:00:00 EDT

A Comparison of Prostaglandin E2 (PGE2) Inhibition of Acuvail(Ketorolac 0.45%), Xibrom (Bromfenac 0.09%)and Nevanac (Nepafenac)in Patients Undergoing Phacoemulsification

Condition:   Cataracts
Interventions:   Drug: Ketorolac Tromethamine;   Drug: Bromfenac;   Drug: nepafenac
Sponsors:   Frank A. Bucci, Jr., M.D.;   Allergan
Completed

Mon, 30 Nov 2009 12:00:00 EST

Ketorolac for Analgesia followiNG Autologous Breast RecOnstructiOn

Condition:   Breast Cancer Female
Interventions:   Drug: Ketorolac Tromethamine;   Drug: Normal Saline
Sponsor:   Nova Scotia Health Authority
Withdrawn

Mon, 02 Jan 2017 12:00:00 EST

A Comparison of Peak Aqueous Penetration of Acuvail (Ketorolac 0.45%), Xibrom (Bromfenac 0.09%), and Nevanac (Nepafenac 0.1%)in Patients Undergoing Phacoemulsification

Condition:   Cataracts
Interventions:   Drug: Ketorolac Tromethamine 0.45%;   Drug: bromfenac 0.09%;   Drug: nepafenac 0.1%
Sponsors:   Frank A. Bucci, Jr., M.D.;   Allergan
Completed

Tue, 27 Oct 2009 12:00:00 EDT

Ketorolac Premedication for Anesthetic Efficiency of IANB & Postendodontic Pain in Teeth With Irreversible Pulpitis

Condition:   Irreversible Pulpitis
Interventions:   Drug: Ketorolac Tromethamine;   Drug: Placebo
Sponsor:   Cairo University
Unknown status

Thu, 20 Oct 2016 12:00:00 EDT

Comparison of Acular LS With Lotemax to Prevent Inflammation After Cataract Surgery and Intraocular Lens Implantation

Condition:   Cataract Extraction
Interventions:   Drug: Acular LS;   Drug: Lotemax
Sponsor:   Medical University of South Carolina
Completed

Mon, 21 Aug 2006 12:00:00 EDT

Safety and Efficacy of Multiple Doses of Ketorolac Tromethamine Administered Intranasally for Postoperative Pain

Condition:   Postoperative Pain
Interventions:   Drug: Ketorolac tromethamine;   Drug: Placebo
Sponsor:   Egalet Ltd
Completed

Wed, 04 May 2011 12:00:00 EDT

Comparison Of Ketorolac Tromethamine Versus Naproxen For Moderate to Severe Back Pain Treatment

Condition:   Back Pain
Interventions:   Drug: Ketorolac Tromethamine;   Drug: Naproxen
Sponsor:   EMS
Completed

Wed, 16 Nov 2011 12:00:00 EST

Efficacy of Block Injection of an Anti Inflammatory Medicine in Patients With Mandibular Dental Pain

Condition:   Symptomatic Irreversible Pulpitis
Interventions:   Drug: Ketorolac Tromethamine;   Behavioral: Sham injection
Sponsor:   Azad University of Medical Sciences
Completed

Thu, 25 Jan 2018 12:00:00 EST

Efficacy and Safety of Intranasal Ketorolac for the Acute Treatment of Migraine

Condition:   Migraine
Interventions:   Drug: Ketorolac tromethamine;   Drug: Placebo
Sponsor:   Egalet Ltd
Completed

Thu, 07 Jun 2007 12:00:00 EDT

Comparison Of Ketorolac Tromethamine Oral Drops Versus Naproxen For Moderate to Severe Back Pain Treatment

Condition:   Back Pain
Interventions:   Drug: Ketorolac Tromethamine;   Drug: Naproxen
Sponsor:   EMS
Completed

Wed, 16 Nov 2011 12:00:00 EST

Study of the Safety, Tolerability and Analgesic Efficacy of Multiple Doses of Ketorolac Tromethamine (IN) for Postoperative Pain

Condition:   Postoperative Pain
Interventions:   Drug: Ketorolac tromethamine;   Drug: Placebo
Sponsor:   American Regent, Inc.
Completed

Tue, 10 May 2011 12:00:00 EDT

Tolerability, Safety and Pharmacokinetics of Four Formulations of Ketorolac Tromethamine in Healthy Volunteers

Condition:   Healthy Volunteers
Interventions:   Drug: Ketorolac Tromethamine;   Drug: Ketorolac Tromethamine with 4% Lidocaine hydrochloride (HCl);   Drug: Ketorolac Tromethamine with 5% Lidocaine HCl;   Drug: 30 mg Ketorolac Tromethamine with 6% Lidocaine HCl
Sponsor:   Egalet Ltd
Completed

Wed, 18 May 2011 12:00:00 EDT

Ketorol Gel in Gonarthrosis and Low Back Pain

Conditions:   Gonarthrosis;   Low Back Pain
Interventions:   Drug: Ketorolac Tromethamine;   Drug: Ketoprofen
Sponsor:   Dr. Reddy's Laboratories Limited
Completed

Wed, 23 Dec 2015 12:00:00 EST

Effect of Toradol on Post-operative Foot and Ankle Healing

Conditions:   Ankle Fractures;   Trauma Injury
Interventions:   Drug: Ketorolac;   Other: No ketorolac
Sponsor:   Rothman Institute Orthopaedics
Completed

Thu, 01 Nov 2018 12:00:00 EDT

Efficacy of Ketorolac Buccal Infiltration on Success Rate of Inferior Alveolar Nerve Block

Condition:   Failed Mechanical Induction
Interventions:   Drug: Ketorolac Tromethamine;   Drug: Placebo
Sponsor:   Nahid Mohammadzadeh Akhlaghi
Completed

Mon, 31 Aug 2015 12:00:00 EDT

Aqueous Concentrations and PGE2 Inhibition of Ketorolac 0.4% vs. Bromfenac 0.09% in Cataract Patients: Trough Drug Effects

Condition:   Cataract
Intervention:   Drug: Acular, Xibrom
Sponsor:   Innovative Medical
Completed

Fri, 04 May 2007 12:00:00 EDT

Safety and Pharmacokinetics Study of Intranasal Ketorolac in Elderly and Nonelderly Adult Healthy Subjects

Condition:   Healthy Subjects
Intervention:   Drug: Ketorolac tromethamine
Sponsor:   American Regent, Inc.
Completed

Fri, 03 Jun 2011 12:00:00 EDT

Effect of Preoperative Topical Ketorolac on Aqueous Cytokine Levels and Macular Thickness in Cataract Surgery Patients

Conditions:   Cystoid Macular Edema, Postoperative;   Diabetes Mellitus
Intervention:   Drug: Ketorolac tromethamine ophthalmic solution 0.45%
Sponsor:   University of Malaya
Completed

Tue, 05 Jan 2016 12:00:00 EST

Study of Whether 15 mg Dose of Ketorolac IV is as Effective as a 30 mg Dose.

Conditions:   Pain;   Pain, Postoperative
Intervention:   Drug: Ketorolac Tromethamine
Sponsor:   University of Calgary
Unknown status

Fri, 29 Oct 2010 12:00:00 EDT

Study to Assess the Absorption and Tolerability of Intranasal Ketorolac Tromethamine and to Assess the Effects of Oxymetazoline Hydrochloride and Fluticasone Propionate on the Absorption and Tolerability of Intranasal Ketorolac Tromethamine in Participants With Allergic Rhinitis

Condition:   Allergic Rhinitis
Interventions:   Drug: Ketorolac Tromethamine;   Drug: Oxymetazoline Hydrochloride;   Drug: Fluticasone Propionate
Sponsor:   Egalet Ltd
Completed

Fri, 03 Jun 2011 12:00:00 EDT

Ketorolac Plus Tobramycin/Dexamethasone Versus Tobramycin/Dexamethasone After Uneventful Phacoemulsification Surgery

Condition:   Cataract
Interventions:   Drug: Drug: Tobramycin 0.3% - Dexamethasone 0.1%;   Drug: Drug: Tobramycin-Dexamethasone plus Ketorolac tromethamine
Sponsor:   Veroia General Hospital
Completed

Wed, 14 Apr 2010 12:00:00 EDT

Effect of Spinal Ketorolac on Mechanical Hypersensitivity After a Total Hip Replacement

Condition:   Hip Arthroplasty
Interventions:   Drug: ketorolac tromethamine opthalmic solution;   Drug: placebo
Sponsors:   Wake Forest University;   National Institute of General Medical Sciences (NIGMS)
Terminated

Fri, 22 Feb 2008 12:00:00 EST

Study Evaluating the Effects of Toradol and Lyrica for Pain Control After Donor Nephrectomy

Condition:   Pain, Postoperative
Interventions:   Drug: Ketorolac;   Drug: Pregabalin;   Drug: Placebo oral capsule;   Drug: Saline
Sponsor:   University of Utah
Completed

Thu, 13 Sep 2018 12:00:00 EDT

Comparison of Pain Sensation During Single Use of Two Topical Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)

Condition:   Pain
Interventions:   Drug: Nevanac;   Drug: Acular LS
Sponsor:   Santa Casa de Misericordia de Santos
Unknown status

Wed, 25 Mar 2009 12:00:00 EDT

The Use of Intranasal Ketoralac for Pain Management (Sprix)

Conditions:   Postoperative Pain Management;   Urolithiasis
Interventions:   Drug: Intranasal Ketoralac;   Drug: Placebo
Sponsor:   Montefiore Medical Center
Terminated

Thu, 29 Nov 2012 12:00:00 EST

S.L. Spray Solution® and Difflam® and Acular®Spray for the Prevention of Postoperative Sore Throat

Condition:   Sore Throat
Interventions:   Drug: S.L.®;   Drug: Difflam Forte ®;   Drug: Acular®;   Drug: placebo
Sponsor:   Chang Gung Memorial Hospital
Completed

Fri, 20 Nov 2015 12:00:00 EST

Premedication Efficacy of Oral Ketorolac and Ketorolac/ Acetaminophen on Post Treatment Pain

Condition:   Irreversible Pulpitis
Interventions:   Drug: Ketorolac tromethamine;   Drug: Acetaminophen;   Drug: Placebo
Sponsor:   Azad University of Medical Sciences
Completed

Wed, 25 Nov 2015 12:00:00 EST

Effect of Premedication on Success of Inferior Alveolar Nerve Block Injection

Condition:   Irreversible Pulpitis
Interventions:   Drug: Ketorolac Tromethamine;   Drug: Acetaminophen;   Other: Placebo
Sponsor:   Azad University of Medical Sciences
Completed

Wed, 11 Nov 2015 12:00:00 EST

The Role of Prostaglandins in the Progression of Diabetic Retinopathy

Condition:   Inflammation
Interventions:   Drug: Acuvail;   Other: Placebo
Sponsor:   Vanderbilt University
Withdrawn

Fri, 01 Jun 2012 12:00:00 EDT

Nepafenac 0.1% Eye Drops, Suspension Compared to Ketorolac Trometamol 0.5% Eye Drops, Solution and Placebo

Condition:   Cataracts
Interventions:   Drug: Nepafenac 1mg/ml eye drops, suspension;   Drug: Ketorolac Trometamol 5 mg/ml eye drops, solution;   Other: Nepafenac vehicle eye drops
Sponsor:   Alcon Research
Completed

Thu, 30 Nov 2006 12:00:00 EST

Safety and Efficacy of Multiple Doses of Intranasal Ketorolac in Postoperative Pain Following Major Abdominal Surgery

Condition:   Postoperative Pain
Interventions:   Drug: Intranasal Ketorolac Tromethamine;   Drug: Intranasal Placebo
Sponsor:   Egalet Ltd
Completed

Mon, 19 Dec 2005 12:00:00 EST

A Comparison of Post Phacoemulsification Aqueous Flare in Patients Using Ketorolac 0.45% 2 Times Daily (BID) and Bromfenac 0.09% 2 Times Daily (BID)

Condition:   Post Operative Anterior Chamber Inflammation (Flare)
Interventions:   Drug: Ketorolac Tromethamine 0.45%;   Drug: Bromfenac 0.09%
Sponsors:   Bucci Laser Vision Institute;   Allergan
Completed

Wed, 02 Dec 2009 12:00:00 EST

Safety and Efficacy of Olopatadine Hydrochloride/Ketorolac Tromethamine Ophthalmic Solution Compared With Olopatadine Hydrochloride Ophthalmic Solution in Patients With Seasonal Allergic Conjunctivitis

Conditions:   Rhinitis, Allergic, Seasonal;   Conjunctivitis, Allergic
Interventions:   Drug: olopatadine hydrochloride /ketorolac tromethamine fixed dose combination ophthalmic solution;   Drug: olopatadine hydrochloride 0.1% ophthalmic solution
Sponsor:   Allergan
Completed

Fri, 10 Dec 2010 12:00:00 EST

Ketorolac in Postoperative Infants: Pharmacokinetics and Safety

Condition:   Postoperative Pain in Infants
Interventions:   Drug: Ketorolac Tromethamine 1 mg/kg;   Drug: Ketorolac Tromethamine 0.5 mg/kg;   Drug: Placebo
Sponsors:   Seattle Children's Hospital;   University of Washington
Completed

Wed, 15 Dec 2010 12:00:00 EST

NSAIDs Stent Study

Conditions:   Ureteral Stent Placement;   Kidney Stone
Interventions:   Drug: Ketorolac Trometamol 30Mg/1mL Injection;   Drug: Normal saline
Sponsor:   Washington University School of Medicine
Recruiting

Mon, 20 Aug 2018 12:00:00 EDT

Ketorolac Versus Triamcinolone Knee Injections for Osteoarthritis

Condition:   Knee Osteoarthritis
Interventions:   Drug: Ketorolac Tromethamine;   Drug: Triamcinolone Acetonide
Sponsor:   San Antonio Military Medical Center
Completed

Thu, 20 Nov 2014 12:00:00 EST

Administration of Tramadol and Ketorolac Separately and Simultaneously to Assess a Potential Pharmacokinetic Interaction

Condition:   Pharmacokinetics
Interventions:   Drug: Tramadol hydrochloride 25 mg capsule;   Drug: Ketorolac Tromethamine 10 mg tablet
Sponsors:   Grünenthal GmbH;   Grünenthal Colombiana S.A.
Completed

Thu, 06 Dec 2018 12:00:00 EST

Wound Infiltration With Ketorolac Versus Lidocaine for Postoperative Analgesia After Total Abdominal Hysterectomy

Condition:   Anesthesia
Interventions:   Procedure: Wound infiltration;   Drug: Lidocaine Hydrochloride;   Drug: Ketorolac tromethamine
Sponsor:   Ain Shams University
Unknown status

Tue, 09 Jan 2018 12:00:00 EST

Anesthetics and Analgesics in Children

Conditions:   Anesthesia;   Pain
Interventions:   Drug: Ketorolac Tromethamine;   Drug: Hydromorphone
Sponsors:   Kanecia Zimmerman, MD MPH;   The Emmes Company, LLC
Recruiting

Fri, 09 Feb 2018 12:00:00 EST

Ketorolac for Moderate to Severe Abdominal Pain in Children

Conditions:   Abdominal Pain;   Appendicitis;   Analgesia;   Child, Only;   Emergencies
Interventions:   Drug: Ketorolac Tromethamine 10 MG/ML;   Drug: Morphine Sulfate 10Mg/1mL Injection
Sponsor:   Hamilton Health Sciences Corporation
Recruiting

Thu, 27 Aug 2020 12:00:00 EDT

Topical 0.4% Ketorolac and Vitreoretinal Surgery

Condition:   Surgery
Intervention:   Drug: Ketorolac
Sponsor:   Emory University
Completed

Wed, 19 Dec 2007 12:00:00 EST

Nevanac 3-Month Safety Study With QID Dosing

Condition:   Cataract
Interventions:   Drug: Nepafenac ophthalmic solution 0.1%;   Drug: Ketorolac Tromethamine ophthalmic solution 0.4%;   Other: Nepafenac ophthalmic suspension vehicle
Sponsor:   Alcon Research
Completed

Fri, 02 Jun 2006 12:00:00 EDT

Morphological and Functional Evaluation of Irvine-Gass Syndrome

Condition:   Irvine Gass Syndrome
Intervention:   Behavioral: if needed (decided individually) either Acular eye drops, Ultracortenol eye drop or intravitreal triamcinolone injection
Sponsor:   Medical University of Vienna
Completed

Thu, 05 Jan 2012 12:00:00 EST

Effect of Prophylactic Ketorolac on CME After Cataract Surgery

Condition:   Macular Edema, Cystoid
Intervention:   Drug: ketorolac tromethamine 0.5% (Acular®)
Sponsor:   Queen's University
Completed

Fri, 09 Jun 2006 12:00:00 EDT

Ketorolac Irrigant on Post Operative Pain

Condition:   Acute Irreversible Pulpitis With Apical Periodontitis
Interventions:   Other: Ketorolac Tromethamine irrigant;   Other: sodium hypochlorite irrigant
Sponsor:   Cairo University
Not yet recruiting

Tue, 24 Mar 2020 12:00:00 EDT

Premedication Efficacy of Ketorolac Infiltration on Post Endodontic Pain

Condition:   Irreversible Pulpitis
Interventions:   Drug: Ketorolac Tromethamine;   Drug: Placebo
Sponsor:   Azad University of Medical Sciences
Completed

Tue, 04 Oct 2016 12:00:00 EDT

Effect of Ketorolac and Remote Ischemic Preconditioning on Renal Ischemia-reperfusion Injury in Patients Undergoing Partial Nephrectomy

Condition:   Renal Cell Carcinoma
Intervention:   Drug: Ketorolac tromethamine and remote ischemic preconditioning
Sponsor:   Yonsei University
Completed

Fri, 19 Apr 2013 12:00:00 EDT

A 6 Month Study to Evaluate the Safety, Analgesic Efficacy of ACUVAIL™ (Ketorolac Tromethamine Ophthalmic Solution) 0.45%, in Post-PRK Corneal Wound Healing

Condition:   Must be PRK Candidate
Intervention:  
Sponsors:   Durrie Vision;   Allergan
Completed

Wed, 01 Sep 2010 12:00:00 EDT

Pre-operative Ketorolac Administration Has no Pre-emptive Analgesic Effect Following Total Abdominal Hysterectomy

Condition:   Pain
Interventions:   Drug: Ketorolac Tromethamine;   Other: Placebo
Sponsor:   Hospital Arquitecto Marcide
Completed

Wed, 30 Dec 2015 12:00:00 EST

Assessment of Nasal Deposition and Clearance of Ketorolac Solution Administered Using the Valois Nasal Spray Device

Condition:   Healthy Subjects
Intervention:   Drug: Ketorolac tromethamine
Sponsor:   Egalet Ltd
Completed

Thu, 19 May 2011 12:00:00 EDT

Intravenous Ketorolac and Metoclopramide for Pediatric Migraine in the Emergency Department

Conditions:   Probable Migraine;   Migraine With Aura;   Migraine Without Aura
Interventions:   Drug: Ketorolac Tromethamine;   Drug: Metoclopramide
Sponsors:   University of Alberta;   Canadian Institutes of Health Research (CIHR)
Completed

Thu, 10 May 2012 12:00:00 EDT

Analysis for NSAID VS Corticosteroid Shoulder Injection in Diabetic Patients

Conditions:   Rotator Cuff Tear;   Rotator Cuff Injury;   Rotator Cuff Tendinitis;   Diabetes Mellitus
Interventions:   Drug: Ketorolac;   Drug: Triamcinolone Acetonide
Sponsor:   Milton S. Hershey Medical Center
Withdrawn

Tue, 24 Oct 2017 12:00:00 EDT

Topic Ketorolac Added to Panphotocoagulation in Proliferative Diabetic Retinopathy

Conditions:   Proliferative Diabetic Retinopathy;   Macular Edema
Interventions:   Drug: Ketorolac tromethamine;   Drug: Polivynilic alcohol
Sponsor:   Hospital Juarez de Mexico
Completed

Fri, 22 May 2009 12:00:00 EDT

Subacromial Methylprednisolone Versus Ketorolac for Shoulder Impingement

Conditions:   Subacromial Impingement;   Subacromial Impingement Syndrome
Interventions:   Drug: Ketorolac Tromethamine;   Drug: Methylprednisolone Acetate
Sponsor:   The University of Texas Medical Branch, Galveston
Recruiting

Fri, 12 Apr 2019 12:00:00 EDT

A Single-dose Study of Intranasal Ketorolac in the Treatment of Pain Secondary to Dental Impaction Surgery

Conditions:   Pain;   Dental Impaction
Interventions:   Drug: Ketorolac tromethamine;   Drug: Placebo
Sponsor:   Egalet Ltd
Completed

Thu, 19 May 2011 12:00:00 EDT

Tobramycin-Dexamethasone Versus Tobramycin-Dexamethasone Plus Ketorolac After Phacoemulsification Surgery

Condition:   Cataract
Interventions:   Drug: Tobramycin 0.3% - Dexamethasone 0.1%;   Drug: Tobramycin 0.3% - Dexamethasone 0.1% plus Ketorolac tromethamine 0.5%
Sponsor:   Veroia General Hospital
Completed

Fri, 09 Oct 2009 12:00:00 EDT


IV Ketorolac on Platelet Function Post-Cesarean Delivery

Conditions:   Cesarean Section Complications;   Postoperative Pain;   Coagulation Defect; Postpartum;   Nonsteroidals (NSAIDs)Toxicity;   Postpartum Hemorrhage
Interventions:   Drug: Ketorolac Tromethamine 30 MG/ML;   Drug: Placebos
Sponsors:   Beth Israel Deaconess Medical Center;   Society for Obstetric Anesthesia and Perinatology
Recruiting

Tue, 15 Jan 2019 12:00:00 EST

Disposition of Intravenous Ketorolac

Condition:   Postoperative Pain
Intervention:   Drug: Ketorolac Tromethamine
Sponsor:   Universitaire Ziekenhuizen Leuven
Completed

Tue, 08 Feb 2011 12:00:00 EST

Atomized Intranasal Vs Intravenous Ketorolac in Acute Renal Colic Pain Management.

Condition:   Acute Renal Colic
Interventions:   Drug: Intravenous Ketorolac Tromethamine;   Drug: Intranasal Ketorolac Tromethamine
Sponsor:   Oman Medical Speciality Board
Recruiting

Mon, 22 Jun 2020 12:00:00 EDT

Nepafenac Opthalmic Suspension 0.1% Compared to Acular LS for Treatment of Inflammation After Cataract Surgery

Condition:   Cataract
Intervention:   Drug: Nepafenac Ophthalmic Suspension, 0.1%
Sponsor:   Alcon Research
Completed

Fri, 02 Jun 2006 12:00:00 EDT

Femoral Nerve Block Compared to Exparel in Total Knee Replacement

Conditions:   Osteoarthritis;   Pain
Interventions:   Drug: Exparel;   Drug: Femoral Nerve Block Bupivacaine;   Drug: Toradol;   Drug: Morphine Sulfate
Sponsor:   The New England Baptist Hospital
Unknown status

Tue, 16 Jun 2015 12:00:00 EDT

Autonomic Control of the Circulation and VDR

Conditions:   Venous Distension Reflex;   Blood Pressure
Interventions:   Other: Wrist-to-elbow (W-E) occlusion;   Drug: ketorolac tromethamine;   Drug: saline control
Sponsor:   Milton S. Hershey Medical Center
Recruiting

Wed, 02 May 2018 12:00:00 EDT

Knee Injection RCT

Condition:   Osteoarthritis
Interventions:   Drug: Ketorolac Tromethamine Injection;   Drug: Methylprednisolone Acetate Injection;   Drug: Hylan G-F 20
Sponsors:   UConn Health;   Orthopedic Research and Education Foundation
Terminated

Wed, 03 Oct 2018 12:00:00 EDT

Ketolorac Versus Saline at Laparoscopic Incision Sites

Condition:   Pain, Postoperative
Intervention:   Drug: Ketolorac
Sponsor:   The Cleveland Clinic
Withdrawn

Thu, 16 Jun 2011 12:00:00 EDT

Preoperative Ketorolac for Pain Control in Scleral Buckle Surgery

Condition:   Pain
Interventions:   Drug: Ketorolac Tromethamine;   Drug: placebo;   Procedure: scleral buckle
Sponsor:   Sun Yat-sen University
Completed

Wed, 06 Apr 2016 12:00:00 EDT

Anti-inflammatory Efficacy for Prophylaxis of Cystoid Macular Edema (CME) After Phacoemulsification

Conditions:   Cystoid Macular Edema;   Cataract
Interventions:   Drug: Nepafenac;   Drug: Ketorolac
Sponsor:   Hospital Oftalmologico de Brasilia
Completed

Wed, 12 Mar 2014 12:00:00 EDT

Time Serial Analysis on Preemptive Analgesia of Preoperative Topical Diclofenac and Ketorolac in Photorefractive Keratectomy(PRK)

Condition:   Myopes Who Have Undergone PRK.
Interventions:   Drug: topical ketorolac 0.5% (Acular®, Allergan Inc, Irvine, CA);   Drug: topical diclofenac 0.1% (Voltaren®, Novartis, Bern, Switzerland)
Sponsor:   Yonsei University
Completed

Fri, 04 Jan 2013 12:00:00 EST

Intranasal Ketorolac for Postsurgical Pain in Dental Implant Patients

Condition:   Acute Pain
Intervention:   Drug: Ketorolac Nasal Spray
Sponsor:   Hersh, Elliot V., DMD, MS, PhD
Completed

Tue, 13 Dec 2011 12:00:00 EST

Collagen Crosslinking With Ultraviolet-A in Asymmetric Corneas

Conditions:   Keratoconus;   Ectasia;   Degeneration
Interventions:   Drug: Ciprofloxicine or Vigamox or other.;   Drug: Nonsteroidal (Acular, Voltaren Xibrom, etc);   Drug: Steroid (FML, Pred Forte, Flarex, etc.)
Sponsor:   Cxlusa
Terminated

Wed, 02 Dec 2009 12:00:00 EST

Cross-linking of Corneal Collagen (CXL) With Ultraviolet-A in Asymmetric Corneas

Conditions:   Keratoconus;   Ectasia;   Degeneration
Interventions:   Drug: Ciprofloxicin or Vigamox or other.;   Drug: Nonsteroidal (Acular, Acuvail, Voltaren Xibrom, etc);   Drug: Steroid (FML, Pred Forte, Flarex, etc.)
Sponsor:   Cxlusa
Terminated

Fri, 27 Aug 2010 12:00:00 EDT

An Efficacy and Safety Trial of Intranasal Ketorolac in Emergency Department Patients for the Treatment of Acute Pain

Condition:   Other Acute Pain
Intervention:   Drug: intranasal ketorolac
Sponsors:   The Cleveland Clinic;   American Regent, Inc.
Completed

Tue, 15 Nov 2011 12:00:00 EST

A Randomized Controlled Trial of IV Ketorolac to Prevent Post-ERCP Pancreatitis

Condition:   Pancreatitis
Interventions:   Drug: Ketorolac;   Drug: Placebo
Sponsor:   University of California, San Francisco
Not yet recruiting

Mon, 08 Jun 2015 12:00:00 EDT

Intranasal Ketorolac Versus Intravenous Ketorolac for Treatment of Migraine Headaches in Children

Condition:   Migraine
Interventions:   Drug: Ketorolac, intranasal;   Drug: Ketorolac, intravenous;   Drug: Placebo, intravenous;   Drug: Placebo, intranasal
Sponsors:   Columbia University;   Migraine Research Foundation
Completed

Mon, 09 Feb 2015 12:00:00 EST

Intravenous Lidocaine and Ketorolac for Pain Management

Condition:   Pain
Interventions:   Drug: Lidocaine;   Drug: Ketorolac Tromethamine;   Drug: Normal Saline Drip;   Drug: Normal Saline Push
Sponsor:   Antonios Likourezos
Completed

Fri, 16 Sep 2016 12:00:00 EDT

Availability & Effect of Post-OP Ketorolac on Ovarian, Fallopian Tube or Primary Peritoneal Cancer

Conditions:   Fallopian Tube Cancer;   Ovarian Cancer;   Peritoneal Cavity Cancer
Intervention:   Drug: Ketorolac
Sponsor:   New Mexico Cancer Care Alliance
Completed

Wed, 22 Aug 2012 12:00:00 EDT

Effect of Anti-inflammatory Topical Prednisolone, Nepafenac and Ketorolac in Intra-operative Mydriasis in Facetectomies

Condition:   Cataract
Interventions:   Drug: prednisolone acetate 1%;   Drug: ketorolac tromethamine 0.4%;   Drug: nepafenac 0.1%;   Drug: methylcellulose 0.5%
Sponsor:   Clinica Oftamologica Zona Sul
Unknown status

Thu, 19 Mar 2009 12:00:00 EDT

Pain Control for Intrauterine Device Placement: A Trial of Ketorolac Prior to Intrauterine Device Placement

Condition:   Pain Control With IUD Insertion
Interventions:   Drug: Ketorolac;   Drug: Normal Saline
Sponsor:   Lynn Ngo
Completed

Tue, 14 Aug 2012 12:00:00 EDT

A 3-Month Clinical Trial to Assess the Safety and Efficacy of the OZURDEX® Intraocular Implant in Patients With Diabetes Mellitus

Conditions:   Macular Edema;   Diabetes Mellitus
Interventions:   Drug: Dexamethasone intravitreal implant;   Drug: Steroid plus NSAID eye drop combination therapy
Sponsors:   Retinal Consultants of Arizona;   Allergan
Completed

Mon, 27 Aug 2012 12:00:00 EDT

Pain Outcomes of Non-opioid vs. Opioid Analgesia for Kidney Stone Surgery.

Condition:   Nephrolithiasis
Interventions:   Drug: Ketorolac Oral Tablet [Toradol];   Drug: Acetaminophen;   Drug: Oxycodone Acetaminophen
Sponsor:   Montefiore Medical Center
Recruiting

Thu, 12 Jul 2018 12:00:00 EDT

Pre-Incisional Ketorolac for Patients Undergoing Surgery for Non-Small Cell Lung Cancer and Renal Cell Carcinoma

Conditions:   Non-small Cell Lung Cancer;   Renal Cell Carcinoma
Intervention:   Drug: Preoperative Ketorolac
Sponsor:   Emory University
Recruiting

Mon, 03 Aug 2020 12:00:00 EDT

Ketorolac Sublingual vs. Fentanyl Intranasal in Pain Control for Bilateral Myringotomy and Tubes (BMT) Placement in Children

Conditions:   Pain, Postoperative;   Otitis Media
Interventions:   Drug: Ketorolac;   Drug: Fentanyl
Sponsor:   Anica Crnkovic
Recruiting

Tue, 12 Jan 2016 12:00:00 EST

ON-Q Pump Infusion of Ketorolac and Ropivacaine at the Wound Site for Postoperative Pain Management

Condition:   Postoperative Pain
Interventions:   Drug: Ketorolac;   Drug: Ketorolac and Ropivacaine
Sponsors:   Maimonides Medical Center;   I-Flow
Completed

Wed, 19 Mar 2008 12:00:00 EDT

Intravenous Ketorolac for Postoperative Pain in Laparoscopic Donor Nephrectomy

Conditions:   Nephrectomy;   Laparoscopic Donor Nephrectomy
Interventions:   Drug: Ketorolac;   Drug: Placebo
Sponsor:   Mayo Clinic
Completed

Thu, 02 Oct 2008 12:00:00 EDT

Intravenous Ketorolac for Postoperative Pain in Percutaneous Nephrolithotomy

Conditions:   Renal Calculus;   Kidney Stones
Interventions:   Drug: Ketorolac;   Drug: Placebo
Sponsor:   Mayo Clinic
Completed

Thu, 02 Oct 2008 12:00:00 EDT

Trial Comparing Ketorolac Tromethamine 0.4% & Prednisolone Acetate 1% in Reducing Post-SLT Anterior Chamber Flare & Cells

Conditions:   Postoperative Complications;   Inflammation;   Glaucoma, Open-Angle
Intervention:  
Sponsor:   University of Pittsburgh
Terminated

Tue, 12 Dec 2006 12:00:00 EST

A Prospective Randomized Double-Blind Trial Comparing 3 Doses of Intravenous Ketorolac for Pain Management

Condition:   Pain
Interventions:   Drug: 10 mg of Ketorolac;   Drug: 15 mg of Ketorolac;   Drug: 30 mg of Ketorolac
Sponsor:   Antonios Likourezos
Completed

Wed, 05 Mar 2014 12:00:00 EST

Enhanced Recovery at Cesarean Birth to Improve Postoperative Outcomes and Reduce Postoperative Length of Stay

Condition:   Cesarean Section
Interventions:   Drug: ketorolac;   Other: Chewing Gum;   Procedure: Enhanced Recovery Protocol
Sponsor:   Montefiore Medical Center
Completed

Sun, 06 Nov 2016 12:00:00 EDT

Intramuscular Ketorolac at Two Single-Dose Regimens

Conditions:   Musculoskeletal Pain;   Analgesia;   Adverse Event
Interventions:   Drug: Ketorolac Injection 15 mg;   Drug: Ketorolac Injection 60 mg
Sponsor:   William Beaumont Army Medical Center
Completed

Sun, 21 Feb 2021 12:00:00 EST

Ketorolac in Breast Cancer Surgery

Conditions:   Curative Breast Cancer Surgery;   Inflammatory Positive/Negative Status;   Pre Surgical Incision Administration
Interventions:   Drug: Ketorolac 30 mg IV;   Drug: Placebos
Sponsors:   Université Catholique de Louvain;   Anticancer Fund, Belgium
Completed

Thu, 07 Mar 2013 12:00:00 EST

Psoas Compartment Block Versus Periarticular Local Anesthetic for Total Hip Arthroplasty

Conditions:   Osteoarthritis;   Arthroplasty
Interventions:   Drug: Ropivacaine with NaCl;   Drug: Epinephrine;   Drug: Morphine;   Drug: Ketorolac Tromethamine;   Drug: Ropivacaine
Sponsor:   William Beaumont Hospitals
Completed

Mon, 18 Jan 2016 12:00:00 EST

Prophylactic Ketorolac Post Epiretinal Membrane Surgery

Condition:   Macular Edema
Interventions:   Drug: Ketorolac 0.5%;   Other: Saline drops
Sponsor:   Queen's University
Completed

Thu, 10 Sep 2009 12:00:00 EDT

Anti-inflammatory Therapy Following Selective Laser Trabeculoplasty

Conditions:   Primary Open Angle Glaucoma;   Pseudoexfoliation Glaucoma
Interventions:   Drug: prednisolone 1%;   Drug: ketorolac 0.5%;   Drug: Artificial Tears (Methyl cellulose drops)
Sponsors:   Queen's University;   Pfizer;   Glaucoma Research Society of Canada
Completed

Tue, 12 Jun 2007 12:00:00 EDT

Nasal Fentanyl And Renal Colic

Condition:   Acute Renal Colic
Interventions:   Drug: FENTANYL;   Drug: Ketorolac Tromethamine AND morphine
Sponsor:   Valduce Hospital
Completed

Wed, 20 Apr 2011 12:00:00 EDT

INflammatory MediatorS in the PathophysIology of Diabetic REtinopathy Study

Condition:   Diabetic Retinopathy
Interventions:   Drug: Ketorolac 0.45% ophthalmic solution;   Drug: Placebo - Preservative-free artificial tears;   Other: Aqueous PGE2 and inflammatory cytokines measurements
Sponsors:   Stephen J. Kim, MD;   Allergan;   National Eye Institute (NEI)
Recruiting

Mon, 10 Aug 2020 12:00:00 EDT

Efficacy of Multimodal Perioperative Analgesia With Periarticular Drug Injection in Total Knee Arthroplasty(TKA)

Condition:   Osteoarthritis,Knee
Interventions:   Drug: Ropivacaine;   Drug: Toradol;   Drug: Clonidine;   Drug: Epinephrine
Sponsor:   Towson Orthopaedic Associates
Completed

Tue, 05 Jan 2010 12:00:00 EST

Safety and Efficacy Study of KAI-1678 to Treat Subjects With Postoperative Pain

Condition:   Pain, Postoperative
Interventions:   Drug: Placebo;   Drug: KAI-1678;   Drug: Ketorolac Tromethamine
Sponsors:   KAI Pharmaceuticals;   Trident Clinical Research Pty Ltd
Completed

Wed, 18 Nov 2009 12:00:00 EST

Effect of Morphine, Tramadol, and Ketorolac on Postoperative Stress and Immune Responses

Condition:   Breast Cancer
Interventions:   Drug: Intravenous morphine sulphate;   Drug: Intravenous tramadol HCL;   Drug: Intravenous ketorolac tromethamine
Sponsor:   Assiut University
Unknown status

Thu, 21 May 2015 12:00:00 EDT

ICE T for Post GYN Surgery Pain

Condition:   Opioid Substitution Treatment
Interventions:   Drug: Ketorolac;   Drug: Opioids;   Other: Ice Packs;   Drug: Tylenol;   Drug: Motrin;   Drug: dilaudid
Sponsor:   MetroHealth Medical Center
Recruiting

Fri, 14 Jun 2019 12:00:00 EDT

Dexamethasone Versus Ketorolac Injection for the Treatment of Local Inflammatory Hand and Upper Extremity Disorders

Conditions:   DeQuervains Tenosynovitis;   Lateral Epicondylitis;   Tennis Elbow;   Trigger Finger;   Tenosynovitis;   Inflammatory Disease
Interventions:   Drug: Ketorolac;   Drug: Dexamethasone
Sponsor:   NYU Langone Health
Terminated

Fri, 17 Oct 2014 12:00:00 EDT

Betamethasone Versus Ketorolac Injection for the Treatment of DeQuervains Tenosynovitis

Condition:   DeQuervain Tendinopathy
Interventions:   Drug: betamethasone;   Drug: Ketorolac
Sponsor:   OrthoCarolina Research Institute, Inc.
Active, not recruiting

Fri, 13 Nov 2015 12:00:00 EST

Efficacy of Intravenous Ibuprofen Compared to Intravenous Ketorolac for Pain Control Following Arthroscopic Knee Surgery

Condition:   Pain
Interventions:   Drug: IV ibuprofen;   Drug: Ketorolac
Sponsor:   Cumberland Pharmaceuticals
Completed

Wed, 17 Jul 2013 12:00:00 EDT

The Analgesic Efficacy of Magnesium and Ketorolac in Ultrasound Supraclavicular Block

Condition:   Postoperative Pain
Interventions:   Drug: Magnesium sulfate;   Drug: Ketorolac Tromethamine;   Procedure: supraclavicular block
Sponsor:   Fayoum University Hospital
Recruiting

Fri, 18 Sep 2020 12:00:00 EDT

Efficacy of Ketorolac 0.4% in Prostaglandin Suppression

Condition:   Inflammation
Interventions:   Drug: Ketorolac 0.4%;   Drug: Lubricating Eye Drop
Sponsor:   Allergan
Completed

Fri, 14 Nov 2008 12:00:00 EST

Study of Ketorolac Versus Opioid for Pain After Endoscopy

Conditions:   Kidney Calculi;   Ureteral Calculi
Interventions:   Drug: Oxycodone;   Drug: Ketorolac
Sponsor:   The Cleveland Clinic
Completed

Mon, 25 Mar 2019 12:00:00 EDT

Oral Ketorolac for Pain Relief During IUD Insertion

Condition:   Contraception
Interventions:   Drug: Ketorolac;   Drug: Placebo
Sponsor:   OhioHealth
Completed

Thu, 26 Jan 2017 12:00:00 EST

Treatment of Acute Pancreatitis With Ketorolac

Condition:   Acute Pancreatitis
Intervention:   Drug: Ketorolac
Sponsor:   Ilam University of Medical Sciences
Terminated

Wed, 31 Aug 2016 12:00:00 EDT

Treatment of Post-surgical Cystoid Macular Edema With Topical Steroids Trial (TEMPEST-1)

Condition:   Post-surgical Cystoid Macular Edema (PSCME)
Intervention:   Drug: PredA + Kelac
Sponsor:   Johns Hopkins University
Completed

Wed, 16 Jan 2013 12:00:00 EST

Evaluation of GTPase Inhibition by Post-operative Intravenous Ketorolac in Ovarian Cancer Patients

Conditions:   Ovarian Cancer;   Fallopian Tube Cancer;   Peritoneal Cancer
Interventions:   Drug: Ketorolac;   Other: Placebo
Sponsor:   New Mexico Cancer Care Alliance
Active, not recruiting

Fri, 12 Jun 2015 12:00:00 EDT

Pharmacokinetics of Intranasal Ketorolac in Children

Conditions:   Evaluating Pharmacokinetics of Intranasal Ketorolac;   Pain
Intervention:   Drug: Ketorolac
Sponsor:   Columbia University
Terminated

Fri, 21 Nov 2014 12:00:00 EST

Dose Response of Ketorolac in Knee Arthroscopy

Condition:   Meniscectomy
Intervention:   Drug: Ketorolac Dose
Sponsor:   Medical University of South Carolina
Completed

Fri, 04 Jul 2014 12:00:00 EDT

Intramuscular Ketorolac Versus Oral Ibuprofen for Pain Relief in First Trimester Suction Curettage

Condition:   Pain
Interventions:   Drug: Ketorolac;   Drug: Ibuprofen
Sponsors:   Planned Parenthood League of Massachusetts;   Society of Family Planning
Completed

Thu, 10 May 2012 12:00:00 EDT

Comparison of Ketorolac Nasal Spray to Sumatriptan Nasal Spray and Placebo for Acute Treatment of Migraine

Condition:   Migraines
Interventions:   Drug: Ketorolac;   Drug: Sumatriptan;   Drug: Placebo
Sponsors:   Johns Hopkins University;   American Regent, Inc.
Completed

Fri, 08 Mar 2013 12:00:00 EST

Protein Profile of Immunoregulatory Factors in Diabetic Cataract

Conditions:   Cataract;   Type 2 Diabetes Mellitus
Intervention:   Drug: Ketorolac
Sponsor:   University of Zagreb
Completed

Tue, 16 Apr 2013 12:00:00 EDT

A Comparison of Naropin and Ketorolac for Postoperative Analgesia After Total Knee Arthroplasty

Condition:   Postoperative Pain
Interventions:   Drug: Ketorolac;   Drug: Saline
Sponsor:   University of Aarhus
Completed

Wed, 25 Mar 2009 12:00:00 EDT

Post-Operative Treatment With Ketorolac After Abdominal Myomectomy

Conditions:   Febrile Morbidity;   Pain
Interventions:   Drug: ketorolac;   Drug: saline
Sponsors:   Ascher-Walsh, Charles, M.D.;   New York Presbyterian Hospital;   Icahn School of Medicine at Mount Sinai
Completed

Wed, 18 Feb 2009 12:00:00 EST

Steroids Versus Non-steroidal Anti-inflammatory Drugs Following Glaucoma Surgery

Condition:   Glaucoma
Intervention:   Drug: Ketorolac (NSAID) versus Dexamethasone (steroid)
Sponsor:   University Health Network, Toronto
Unknown status

Tue, 11 Aug 2009 12:00:00 EDT

Synergistic Pharmacologic Intervention for Prevention of ROP (SPIPROP Study)

Condition:   Retinopathy of Prematurity
Interventions:   Drug: Caffeine citrate;   Drug: Ibuprofen;   Drug: Ketorolac
Sponsors:   State University of New York - Downstate Medical Center;   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD);   Food and Drug Administration (FDA)
Completed

Thu, 22 Jan 2015 12:00:00 EST

Use of Ketorolac in Management of Post-Operative Pain After Heart Surgery

Condition:   Pain Management Following Cardiopulmonary Bypass Surgery
Interventions:   Drug: Ketorolac;   Other: Placebo
Sponsor:   Weill Medical College of Cornell University
Completed

Mon, 12 Sep 2005 12:00:00 EDT

Radiofrequency Neurotomy In Relieving Chronic Knee Pain

Conditions:   Osteo Arthritis Knee;   Pain, Chronic
Interventions:   Procedure: radiofrequency;   Drug: Paracetamol (conventional);   Drug: Ketorolac Tromethamine (conventional)
Sponsor:   Assiut University
Completed

Fri, 21 Jul 2017 12:00:00 EDT

Comparison of Vitreous Levels of Acular LS 0.04%, Xibrom 0.09%, and Nevanac 0.1%

Condition:   Vitrectomy
Interventions:   Drug: Nepafenac;   Drug: Ketorolac LS, Bromfenac
Sponsor:   Innovative Medical
Completed

Mon, 18 Sep 2006 12:00:00 EDT

Protracted Effect of Combined Nerve Blocks After Total Knee Arthroplasty

Conditions:   Total Knee Arthroplasty;   Pain;   Nerve Blocks
Interventions:   Drug: Dexamethasone 4 mg + Clonidine 75 microgram + Marcaine 90 mg + Adrenaline 90 microgram;   Drug: Dexamethasone 2 mg + Clonidine 37,5 microgram + Marcaine 45 mg + Adrenaline 45 microgram;   Drug: Ropivacaine + Toradol + Adrenaline
Sponsor:   Regionshospitalet Silkeborg
Completed

Thu, 20 Feb 2014 12:00:00 EST

Effect of Spinal Ketorolac After Acute Opioid Exposure

Condition:   Healthy
Interventions:   Drug: ketorolac;   Drug: placebo;   Drug: remifentanil;   Drug: Capsaicin
Sponsors:   Wake Forest University;   National Institute of General Medical Sciences (NIGMS)
Terminated

Fri, 06 Jun 2008 12:00:00 EDT

Relieving Acute Pain (RAP) Study: A Pilot Study

Conditions:   Trauma;   Opioid Use;   Spine Fusion
Interventions:   Drug: Oxycodone;   Drug: Ketorolac;   Other: Placebo
Sponsor:   University of Maryland, Baltimore
Terminated

Thu, 08 Feb 2018 12:00:00 EST

Opiate Free Multimodal Pain Pathway in Elective Foot and Ankle Surgery: A Prospective Study

Conditions:   Bunion of Unspecified Foot;   Bunionette of Unspecified Foot;   Hammertoe;   Ankle Fractures;   Achilles Tendon Surgery
Interventions:   Drug: Acetominophen;   Drug: Toradol;   Drug: Meloxicam;   Drug: Cyclobenzaprine;   Drug: Lyrica
Sponsor:   Prisma Health-Midlands
Enrolling by invitation

Thu, 25 Feb 2021 12:00:00 EST

Efficacy, Safety and Tolerability Study of N1539 in Subjects After Abdominal Laparoscopic Surgery

Condition:   Laparoscopic Surgery
Interventions:   Drug: N1539;   Drug: Ketorolac Tromethamine;   Drug: Placebo
Sponsor:   Alkermes, Inc.
Terminated

Mon, 19 Sep 2011 12:00:00 EDT

Opioid-Free Anesthetic for Tonsillectomy

Conditions:   Anesthesia;   Opioid Use;   Tonsillitis;   Sleep Disorder;   Surgery
Interventions:   Drug: Ketorolac;   Drug: Dexmedetomidine;   Drug: Morphine;   Drug: Fentanyl
Sponsors:   Children's Hospital of Philadelphia;   University of Pennsylvania;   University of Tennessee Health Science Center
Recruiting

Thu, 27 Aug 2020 12:00:00 EDT

Initial Pain Management in Pediatric Pancreatitis: Opioid vs. Non-Opioid

Condition:   Acute Pancreatitis
Interventions:   Drug: Ketorolac;   Drug: Opioid
Sponsors:   Boston Children's Hospital;   The National Pancreas Foundation
Not yet recruiting

Mon, 02 Mar 2020 12:00:00 EST

Prospective Randomized Controlled Trial for Pain Relief After Office Ureteral Stent Removal

Conditions:   Pain;   Urinary Stone;   Urinary Calculi
Interventions:   Drug: Ketorolac;   Drug: normal saline
Sponsor:   University of Texas Southwestern Medical Center
Completed

Wed, 02 Oct 2019 12:00:00 EDT

Inflammatory Markers in Trauma Patient Outcomes

Condition:   Polytrauma
Interventions:   Drug: Ketorolac;   Drug: Saline Solution
Sponsor:   Arun Aneja
Recruiting

Fri, 14 Sep 2018 12:00:00 EDT

A Comparative Efficacy Trial of IV Acetaminophen Versus IV Ketorolac for Emergency Department Treatment of Generalized Headache

Condition:   Headache
Interventions:   Drug: Ketorolac;   Drug: Acetaminophen
Sponsors:   Spectrum Health - Lakeland;   Michigan State University
Unknown status

Wed, 21 Mar 2018 12:00:00 EDT

Effect of Ketorolac on Post Adenotonsillectomy Pain

Condition:   Obstructive Sleep Apnea
Interventions:   Drug: Ketorolac;   Drug: Standard of Care
Sponsor:   Emory University
Recruiting

Fri, 16 Mar 2018 12:00:00 EDT

Comparing Intra-articular Corticosteroid to Intra-articular Ketorolac Knee Injections

Condition:   Knee Osteoarthritis
Interventions:   Drug: Ketorolac;   Drug: Betamethasone
Sponsor:   St. Luke's Hospital, Pennsylvania
Unknown status

Mon, 23 Nov 2015 12:00:00 EST

A Pilot Study on the Use of Methoxyflurane (Penthrox®) for Pain Control in the Emergency Department

Condition:   Acute Traumatic Pain
Interventions:   Drug: Methoxyflurane;   Drug: Ketorolac
Sponsor:   Hospital Authority, Hong Kong
Completed

Fri, 06 Nov 2020 12:00:00 EST

Anesthesia Preference for Intravitreal Injection: Topical or Subconjunctival

Conditions:   Age-related Macular Degeneration;   Central Retinal Vein Occlusion;   Diabetic Macular Edema
Interventions:   Procedure: Xylocaine 2% Injectable Anesthetic;   Drug: Proparacaine Hydrochloride 0.5% Drop;   Drug: Tetravisc 0.5% Gel;   Drug: Acuvail;   Drug: Intra-vitreal Anti-VEGF Drug
Sponsor:   Retina Vitreous Associates of Florida
Completed

Fri, 13 Jul 2012 12:00:00 EDT

Lidocaine vs Ketorolac for Management of Renal Colic in the Emergency Department

Condition:   Renal Colic
Interventions:   Drug: Lidocaine;   Drug: Ketorolac
Sponsor:   The Brooklyn Hospital Center
Unknown status

Tue, 02 May 2017 12:00:00 EDT

Multimodal Pain Management for Cesarean Delivery

Condition:   Pain
Interventions:   Drug: Intravenous acetominophen;   Drug: Ketorolac, intramuscular;   Drug: Bupivacaine, subcutaneous;   Drug: Normal saline
Sponsor:   The University of Texas Medical Branch, Galveston
Completed

Tue, 04 Oct 2016 12:00:00 EDT

The Impact of IV Acetaminophen on Pain After Appendectomy for Perforated Appendicitis

Condition:   Perforated Appendicitis
Interventions:   Drug: IV tylenol;   Drug: No IV tylenol;   Drug: Ketorolac
Sponsor:   Children's Mercy Hospital Kansas City
Completed

Mon, 29 Aug 2016 12:00:00 EDT

IM Ketorolac vs Cambia for the Acute Treatment of Severe Migraine

Condition:   Migraine Headache
Interventions:   Drug: Diclofenac postassium powder for oral solution and placebo injection;   Drug: Ketorolac intramuscular injection and placebo oral solution
Sponsors:   Scripps Health;   Depomed
Unknown status

Tue, 26 Jan 2016 12:00:00 EST

Liposomal Bupivacaine (Exparel) for Postoperative Pain Control for Open and Laparoscopic Abdominal Hernia Repair

Condition:   Pain
Interventions:   Drug: EXPAREL;   Drug: Ketorolac;   Procedure: laparoscopic abdominal hernia repair;   Procedure: an open surgery for abdominal hernia repair
Sponsors:   Michael Moncure, MD;   Pacira Pharmaceuticals, Inc
Completed

Thu, 01 May 2014 12:00:00 EDT

A Pilot Study to Determine the Efficacy of Intravenous Ibuprofen for Pain Control Following Arthroscopic Knee Surgery

Condition:   Arthroscopic Knee Surgery
Interventions:   Drug: IV ibuprofen;   Drug: IV ketorolac
Sponsor:   Cumberland Pharmaceuticals
Completed

Thu, 26 Jul 2012 12:00:00 EDT

Ketorolac Versus Ibuprofen to Treat Painful Episodes of Sickle Cell Disease

Conditions:   Hematologic Diseases;   Anemia, Sickle Cell
Interventions:   Drug: Intravenous Ketorolac;   Drug: Ibuprofen
Sponsors:   Children's Hospital Medical Center, Cincinnati;   National Heart, Lung, and Blood Institute (NHLBI);   University of Texas Southwestern Medical Center
Terminated

Wed, 22 Jun 2005 12:00:00 EDT

Metoclopramide Versus Ketorolac for Tension-type Headache

Condition:   Headache
Interventions:   Drug: Metoclopramide;   Drug: Ketorolac
Sponsor:   Montefiore Medical Center
Completed

Wed, 11 Nov 2009 12:00:00 EST

Assessment and Prevention of Acute Post-herniotomy Pain

Condition:   Hernia
Interventions:   Drug: Ketorolac postoperative;   Drug: postoperative Patrol;   Drug: intraoperative analgesia
Sponsors:   IRCCS Policlinico S. Matteo;   University of Pavia
Completed

Fri, 29 Apr 2011 12:00:00 EDT

Toradol v. Celecoxib for Postoperative Pain

Condition:   Pain, Postoperative
Interventions:   Drug: Celecoxib;   Drug: Ketorolac
Sponsor:   University of Tennessee Health Science Center
Completed

Mon, 06 Nov 2017 12:00:00 EST

A Pilot Study Comparing the Analgesic Efficacy of IV Ibuprofen and IV Ketorolac

Condition:   Chronic Pelvic Pain
Interventions:   Drug: IV Ibuprofen;   Drug: IV Ketorolac
Sponsors:   Culpeper Surgery Center;   Cumberland Pharmaceuticals
Unknown status

Mon, 23 Jan 2012 12:00:00 EST

The Effect of Different Drugs in the Prevention of Tooth Sensitivity Caused by Tooth Bleaching Treatment.

Condition:   Hydrogen Peroxide Allergy
Interventions:   Drug: acetam/ketoro tromet group;   Drug: Placebo group
Sponsors:   Universidade Estadual de Ponta Grossa;   Coordenação de Aperfeiçoamento de Pessoal de Nível Superior.;   Universidade Estadual do Oeste do Paraná
Completed

Fri, 17 Nov 2017 12:00:00 EST

Intraperitoneal Infusion of Analgesic for Postoperative Pain Management

Conditions:   Hysterectomy;   Gynecologic Surgical Procedures;   Narcotic Use;   Pain, Postoperative
Interventions:   Drug: Ropivacaine Infusion from ON-Q Pump;   Drug: Ropivacaine + Ketorolac Infusion from ON-Q Pump;   Drug: Normal Saline Infusion from ON-Q Pump
Sponsors:   George Washington University;   Avanos Medical
Recruiting

Thu, 17 Oct 2019 12:00:00 EDT

Opioid-Free Shoulder Arthroplasty

Conditions:   Opioid Use;   Shoulder Osteoarthritis;   Avascular Necrosis;   Rotator Cuff Tear;   Arthritis;Inflammatory
Interventions:   Drug: Gabapentin;   Drug: Celecoxib;   Drug: toradol;   Drug: acetaminophen;   Drug: regional block;   Drug: propofol;   Drug: IV lidocaine;   Drug: rocuronium;   Drug: vecuronium;   Drug: sevoflurane;   Drug: desflurane
Sponsor:   OrthoCarolina Research Institute, Inc.
Completed

Wed, 30 May 2018 12:00:00 EDT

Treatment of Acute Pseudophakic Cystoid Macular Edema: Bromfenac 0.09% Versus Diclofenac Sodium 0.1% Versus Ketorolac Tromethamine 0.5%

Condition:   Acute Pseudophakic Cystoid Macular Edema
Interventions:   Drug: Bromfenac;   Drug: Ketorolac;   Drug: Diclofenac
Sponsor:   Bp Consulting, Inc
Completed

Wed, 16 Jan 2008 12:00:00 EST

Local Infiltration Analgesia After Abdominal Hysterectomy

Condition:   Pain
Interventions:   Drug: ropivacaine, ketorelac and epinephrine;   Drug: Placebo
Sponsor:   Göteborg University
Completed

Mon, 04 Feb 2013 12:00:00 EST

Ice T Postoperative Multimodal Pain Regimen in FPMRS Surgery

Conditions:   Pain, Postoperative;   Pelvic Organ Prolapse
Interventions:   Drug: Ice T;   Drug: Motrin/Percocet/Dilaudid for breakthrough
Sponsor:   University Hospitals Cleveland Medical Center
Completed

Tue, 14 Feb 2017 12:00:00 EST

A Comparison of Topical Nepafenac to Placebo in Corneal Epithelial Healing Times and Postoperative Pain Relief

Condition:   Photorefractive Keratectomy
Interventions:   Drug: nepafenac 0.1%;   Other: ketorolac 0.4%
Sponsors:   Alcon Research;   Matthew Caldwell
Completed

Mon, 29 May 2006 12:00:00 EDT

Status Migrainosus - Differentiating Between Responders and Non-responders

Condition:   Migraine
Interventions:   Drug: Bupivacaine;   Drug: Naratriptan Pill;   Drug: Dexamethasone;   Drug: Ketorolac
Sponsor:   Hartford HealthCare
Unknown status

Tue, 28 Feb 2017 12:00:00 EST

Opioid-Free Pain Control Regiment Following Robotic Radical Prostatectomy

Condition:   Radical Prostatectomies
Interventions:   Drug: Tramadol;   Drug: Gabapentin;   Drug: Hydrocodone-Acetaminophen;   Drug: Oxycodone-Acetaminophen;   Drug: Ketorolac;   Drug: Acetaminophen;   Drug: Ketorolac tromethamine;   Drug: Ketamine
Sponsor:   Wake Forest University Health Sciences
Not yet recruiting

Fri, 25 Jun 2021 12:00:00 EDT

Morphine PK Subgroup Analysis

Condition:   Post Operative Pain
Intervention:   Drug: Morphine
Sponsor:   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Completed

Thu, 24 Mar 2011 12:00:00 EDT

Platelet Function and Safety After IV and Oral Diclofenac, IV Ketorolac and Oral Aspirin in Adult Volunteers

Condition:   Healthy
Interventions:   Drug: intravenous diclofenac sodium (DIC075V);   Drug: ketorolac;   Drug: oral diclofenac (Cataflam);   Drug: aspirin
Sponsor:   Javelin Pharmaceuticals
Completed

Wed, 24 Oct 2007 12:00:00 EDT

Postoperative Pain Treatment in Total Hip Arthroplasty: A Study to Assess the Effect of Local Analgesia

Condition:   Pain, Postoperative
Interventions:   Drug: Ropivacaine, Ketorolac and Adrenalin;   Drug: Placebo
Sponsor:   Vejle Hospital
Completed

Mon, 28 Jan 2008 12:00:00 EST

Effectiveness of Corticosteroid vs Ketorolac Shoulder Injections

Conditions:   Full-thickness Rotator Cuff Tear;   Rotator Cuff Tendinitis
Interventions:   Drug: Ketorolac;   Drug: Marcaine;   Drug: Kenalog
Sponsor:   Michael Khazzam
Not yet recruiting

Thu, 20 May 2021 12:00:00 EDT

Effectiveness of Corticosteroid vs. Ketorolac Shoulder Injections: A Prospective Double-Blinded Randomized Trial

Conditions:   Full Thickness Rotator Cuff Tear;   Rotator Cuff Tendinitis
Interventions:   Drug: Ketorolac;   Drug: Marcaine (placebo);   Drug: Kenalog
Sponsor:   Michael Khazzam
Suspended

Fri, 04 Oct 2019 12:00:00 EDT

TPI Medication Comparison - Ketorolac, Lidocaine, or Dexamethasone

Condition:   Myofascial Pain
Interventions:   Drug: Ketorolac;   Drug: Lidocaine;   Drug: Dexamethasone
Sponsor:   University of Utah
Terminated

Mon, 23 Jan 2017 12:00:00 EST

Post-op Acetaminophen vs NSAID Use on Lumbar Spinal Fusion Outcomes

Conditions:   Lumbar Osteoarthritis;   Spondylosis;   Lumbar Disc Disease;   Spinal Stenosis
Interventions:   Drug: Ketorolac;   Drug: Acetaminophen;   Drug: Placebo
Sponsor:   Hospital for Special Surgery, New York
Active, not recruiting

Mon, 07 Mar 2016 12:00:00 EST

Prospective Effect of Intravenous Ketorolac on Opioid Use and Complications Following Cesarean Delivery

Condition:   Analgesia, Obstetrical
Interventions:   Drug: Ketorolac;   Drug: Epidural Morphine;   Drug: Hydromorphone
Sponsor:   University Hospitals Cleveland Medical Center
Unknown status

Tue, 28 Jul 2015 12:00:00 EDT

Magnesium Sulfate Improves Postoperative Analgesia in Laparoscopic Gynecologic Surgeries

Condition:   Pain, Postoperative
Interventions:   Drug: Ketorolac;   Drug: Magnesium;   Drug: Saline solution
Sponsor:   Instituto do Cancer do Estado de São Paulo
Completed

Mon, 27 Jul 2015 12:00:00 EDT

Modulation of Remifentanil-induced Postinfusion Hyperalgesia

Condition:   Hyperalgesia, Secondary
Interventions:   Other: Placebo;   Drug: Remifentanil;   Drug: Ketorolac and remifentanil;   Drug: Parecoxib and remifentanil
Sponsors:   Ullevaal University Hospital;   University of Oslo;   Rikshospitalet University Hospital
Completed

Wed, 05 Nov 2008 12:00:00 EST

Human Cerebral Blood Flow Regulation

Condition:   Cerebral Arterial Diseases
Interventions:   Drug: L-NMMA;   Drug: Ketorolac Tromethamine;   Drug: Ganirelix Acetate;   Drug: Testosterone Transdermal Product;   Drug: Estradiol Topical
Sponsors:   University of Wisconsin, Madison;   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting

Tue, 11 Feb 2020 12:00:00 EST

Peri-articular Injection Utilizing a Pain Cocktail With and Without Exparel

Conditions:   Total Knee Arthroplasty;   Pain Management
Interventions:   Drug: Cocktail;   Drug: Exparel;   Drug: Marcaine
Sponsors:   University of Louisville;   Arthroplasty Foundation, Inc.
Withdrawn

Thu, 08 Oct 2015 12:00:00 EDT

Efficacy and Safety of Escócia Association in the Treatment of Acute Pain

Condition:   Acute Pain
Interventions:   Drug: Escócia association;   Other: Placebo Ketorolac;   Other: Placebo Scopolamine;   Drug: Ketorolac Tromethamine;   Drug: Scopolamine;   Other: Placebo Escócia association
Sponsor:   EMS
Not yet recruiting

Mon, 14 Dec 2020 12:00:00 EST

Efficacy Study of Ketorolac and HPMC to Treat Dry Eye

Condition:   Dry Eye
Interventions:   Drug: Ketorolac/HPMC;   Drug: HPMC;   Drug: Vehicle
Sponsor:   ORA, Inc.
Completed

Tue, 02 Oct 2018 12:00:00 EDT

Dosing of Ketorolac in the Emergency Department

Condition:   Acute Pain
Intervention:   Drug: Ketorolac
Sponsor:   University of Missouri-Columbia
Recruiting

Wed, 14 Mar 2018 12:00:00 EDT

Total Hip Arthroplasty (THA) Lumbar Plexus Verses Periarticular

Condition:   Total Hip Arthroplasty
Interventions:   Drug: PNB Bupivacaine;   Drug: PAI Ropivacaine;   Drug: PAI liposomal bupivacaine;   Drug: Epinephrine;   Drug: Ketorolac
Sponsor:   Mayo Clinic
Completed

Tue, 16 Sep 2014 12:00:00 EDT

Acute Pain and Inflammation After Surgery

Condition:   Knee Injuries
Interventions:   Drug: 1 Ketorolac intraarticular;   Drug: Placebo
Sponsor:   Oslo University Hospital
Completed

Fri, 17 Oct 2008 12:00:00 EDT

Post-Op Pain Control for Prophylactic Intramedullary Nailing.

Conditions:   Bone Metastases;   Lymphoma;   Multiple Myeloma;   Opioid Use;   Pain
Interventions:   Drug: Ketorolac;   Drug: Normal saline;   Drug: Acetaminophen;   Drug: Oxycodone Acetaminophen;   Drug: Morphine;   Drug: Hydrocodone/Acetaminophen;   Drug: Oxycodone
Sponsor:   St. Louis University
Recruiting

Wed, 30 Jan 2019 12:00:00 EST

Management of Postoperative Pain After Total Knee Replacement.

Conditions:   Postoperative Pain;   Knee Replacement Arthroplasty
Interventions:   Drug: Nerve Block;   Drug: Periarticular Injection
Sponsor:   Mark J. Spangehl, M.D.
Completed

Thu, 15 Jul 2010 12:00:00 EDT

Collagen Crosslinking With Ultraviolet-A in Asymmetric Corneas (2)

Conditions:   Keratoconus;   Ectasia;   Degeneration
Intervention:  
Sponsor:   Cxlusa
Terminated

Thu, 01 Apr 2010 12:00:00 EDT

PROUD Study - Preventing Opioid Use Disorders

Conditions:   Anesthesia;   Opioid Use
Interventions:   Behavioral: Guided mindfulness exercises;   Other: Self-administered aromatherapy;   Drug: Baby aspirin;   Drug: Tylenol/Acetaminophen;   Drug: Pregabalin;   Drug: Prednisone;   Drug: Meloxicam;   Drug: Prilosec;   Drug: Tramadol;   Drug: Voltaren;   Drug: Zofran;   Drug: Pepcid;   Drug: Reglan;   Drug: Versed;   Drug: Lidocaine;   Drug: Propofol;   Drug: Ancef;   Drug: Tranexamic Acid (TXA);   Drug: Decadron;   Drug: Bupivacaine hydrochloride;   Drug: Toradol
Sponsor:   Emory University
Recruiting

Tue, 23 Feb 2021 12:00:00 EST

Topical Application of GTN 0.4% in the Treatment of Anismus Following Stapled Haemorrhoidopexy

Condition:   Pain After Stapled Haemorrhoidopexy
Interventions:   Drug: 0.4% nitroglycerin ointment;   Drug: lidocaine cloridrato 2.5% ointment
Sponsor:   University of Roma La Sapienza
Completed

Wed, 19 Jan 2011 12:00:00 EST

Auricular Acupuncture vs SOC in Migraine HA

Condition:   Migraine Headache
Interventions:   Other: Auricular Acupuncture;   Drug: Ketorolac 0.5mg/kg, max 30mg;   Drug: Metoclopramide 0.1 mg/kg, max 10mg;   Drug: Diphenhydramine 1mg/kg, max 50mg;   Drug: Normal saline fluid bolus 20mL/kg, max 1000mL
Sponsor:   University of Louisville
Recruiting

Fri, 12 Feb 2016 12:00:00 EST

Multimodal Pain Study in Free Flap Patients

Conditions:   Head and Neck Cancer;   Analgesia
Interventions:   Drug: Tylenol;   Drug: Oxycodone;   Drug: Morphine;   Drug: Gabapentin;   Drug: toradol;   Drug: Bupivacaine
Sponsor:   University of Kansas Medical Center
Recruiting

Wed, 29 Jan 2020 12:00:00 EST

Serratus Anterior Plane Block for Improving Pain and Respiratory Function in Patients With Multiple Rib Fractures

Condition:   Rib Fracture Multiple
Intervention:   Other: Serratus Anterior Plane Block
Sponsors:   Stanford University;   Society for Academic Emergency Medicine
Recruiting

Tue, 17 Mar 2020 12:00:00 EDT

Intranasal Desmopressin vs IV Ketorolac in Renal Colic Pain Control

Condition:   Renal Colic
Interventions:   Drug: Desmopressin;   Drug: Ketorolac;   Drug: Normal Saline
Sponsor:   Shahid Beheshti University of Medical Sciences
Completed

Wed, 19 Oct 2016 12:00:00 EDT

Multimodal Pain Management After Robotic-Assisted Total Laparoscopic Hysterectomy

Condition:   Pain, Postoperative
Interventions:   Drug: Gabapentin;   Drug: Acetaminophen;   Drug: Celecoxib;   Drug: Ketorolac;   Procedure: Paracervical block with ropivacaine;   Procedure: Local anesthetic injection with ropivacaine at abdominal laparoscopic port sites;   Drug: Hydromorphone;   Drug: Oxycodone
Sponsor:   State University of New York at Buffalo
Recruiting

Thu, 11 Jun 2020 12:00:00 EDT

Mesoglycan for Pain Control After Open Excisional HAEMOrrhoidectomy

Conditions:   Haemorrhoidal Disease;   Post-operative Pain;   Thrombosis
Intervention:   Other: Mesoglycan
Sponsors:   Societa Italiana di Chirurgia ColoRettale;   Gaetano Gallo;   Giuseppe Sammarco;   Giuseppe Clerico;   Alessandro Sturiale;   Michele Manigrasso;   Alberto Realis Luc;   Mario Trompetto
Completed

Wed, 22 Jul 2020 12:00:00 EDT

TAP Block With Liposomal Bupivacaine Versus Pre-incisional Wound Infiltration With Bupivacaine for Postoperative Pain

Condition:   Postoperative Pain
Interventions:   Procedure: Pre-incisional wound infiltration;   Procedure: Laparoscope to place TAP block with liposomal bupivacaine;   Drug: Liposomal bupivacaine;   Drug: Bupivacaine;   Drug: Ketorolac
Sponsor:   University of Tennessee
Terminated

Fri, 27 Mar 2015 12:00:00 EDT

Randomized Study Comparing the Use of Epidural Analgesia to Intravenous Narcotics for Laparoscopic Colorectal Resection.

Condition:   Pain, Postoperative
Interventions:   Procedure: Epidural Analgesia;   Procedure: Parenteral Analgesia (Intravenous)
Sponsor:   University of California, Irvine
Completed

Thu, 13 Mar 2014 12:00:00 EDT

Short-term Additive Effect of Topical Ketorolac on the Management of Diabetic Macular Edema With Intravitreal Bevacizumab

Condition:   DME
Interventions:   Drug: prescription topical ketorolac in group 1;   Drug: prescription artificial tear in group 2;   Drug: prescription topical ketorolac in group 2;   Drug: prescription artificial tear in group1
Sponsor:   Shahid Beheshti University of Medical Sciences
Completed

Wed, 09 Oct 2019 12:00:00 EDT

Comparing Intrathecal Morphine and Intraoperative Lidocaine Infusion to Epidural Anesthesia With Postoperative PCA for Patients Undergoing Exploratory Laparotomy

Conditions:   Cancer Debulking;   Enlarged Uterus;   Fibroid Uterus;   Adnexal Mass
Interventions:   Drug: Bupivacaine;   Drug: Morphine;   Drug: Lidocaine
Sponsors:   Washington University School of Medicine;   The Foundation for Barnes-Jewish Hospital
Not yet recruiting

Mon, 23 Aug 2021 12:00:00 EDT

Use of Local Infiltration Analgesia Following Total Hip Arthroplasty

Conditions:   Pain, Postoperative;   Pain
Interventions:   Drug: ropivacaine and ketorolac;   Drug: Ketorolac
Sponsors:   University of Aarhus;   Lundbeck Foundation
Completed

Fri, 29 Apr 2011 12:00:00 EDT

The Laser in Pseudoexfoliation (LIP) Study

Condition:   Glaucoma
Interventions:   Procedure: SLT Laser;   Drug: Prostagladin
Sponsors:   Marcelo Nicolela;   Dalhousie University
Unknown status

Fri, 12 Oct 2012 12:00:00 EDT

Continuous Infusion Versus Bolus Dosing for Pain Control After Pediatric Cardiothoracic Surgery

Condition:   Congenital Heart Disease
Interventions:   Drug: continuous infusion;   Drug: as needed dosing;   Drug: Acetaminophen;   Drug: ketorolac
Sponsor:   Advocate Health Care
Completed

Mon, 14 Apr 2014 12:00:00 EDT

A Comparison of Bupivacaine and Ketorolac for Postoperative Analgesia After Iliac Crest Bone Harvesting

Condition:   Postoperative Pain
Interventions:   Drug: Ketorolac;   Drug: Bupivacaine;   Drug: ketorolac + bupivacaine
Sponsor:   The Hospital for Sick Children
Completed

Thu, 30 Nov 2006 12:00:00 EST

Novel Multimodal Pain Control Protocol for Minimally Invasive Gynecologic Surgery

Conditions:   Postoperative Pain;   Narcotic Use;   Cryotherapy Effect
Interventions:   Other: Opioid-sparing multimodal pain management;   Other: Usual care
Sponsor:   Ohio State University
Recruiting

Thu, 14 Jan 2021 12:00:00 EST

Ictal and Interictal Inflammatory Markers in Migraine

Condition:   Migraine
Interventions:   Drug: Treximet;   Drug: Placebo
Sponsors:   Johns Hopkins University;   University of Toledo Health Science Campus;   The Cleveland Clinic
Completed

Mon, 07 Jun 2010 12:00:00 EDT

The Effect of Intra-operative Ketorolac on Hematoma Rates in Breast Reduction Surgery

Condition:   Hematoma Postoperative
Interventions:   Drug: Ketorolac;   Drug: Saline
Sponsor:   Dr. Chandran Medical Prof Corp
Recruiting

Thu, 24 May 2018 12:00:00 EDT

Phenotyping Acute Pain for Discovery Research and Directed Therapeutics

Condition:   Post op Pain
Intervention:   Other: questionnaires
Sponsor:   East Carolina University
Withdrawn

Tue, 23 Dec 2014 12:00:00 EST

"THINK Trial: Treatment of Headache With IntraNasal Ketamine: A Randomized Controlled Trial Evaluating the Efficacy of Intranasal Ketamine Versus Standard Therapy in the Management of Primary Headache Syndromes in the Emergency Department"

Conditions:   Headache;   Intranasal Ketamine
Interventions:   Drug: Ketamine;   Drug: Normal saline;   Drug: Metoclopramide;   Drug: Ketorolac;   Drug: Dexamethasone;   Drug: Benadryl
Sponsor:   Brooke Army Medical Center
Completed

Thu, 16 Mar 2017 12:00:00 EDT

Comparative Study Between the Effect of Diclofanic and Ketorolac in Post Tonsillectomy Pain Management

Condition:   Pain, Acute
Interventions:   Drug: diclofenac;   Drug: ketorolac
Sponsor:   Assiut University
Completed

Wed, 07 Jun 2017 12:00:00 EDT

Factors Affecting Perioperative Outcomes

Condition:   Pelvic Organ Prolapse
Intervention:  
Sponsor:   University of Oklahoma
Withdrawn

Thu, 09 Feb 2012 12:00:00 EST

Local Multimodal Injection Versus Regional Anesthesia in Controlling Pain for Treating Rotational Ankle Fractures

Condition:   Ankle Fractures
Interventions:   Drug: Regional anesthesia group;   Drug: Local multimodal analgesia group
Sponsor:   University of Utah
Enrolling by invitation

Wed, 25 Aug 2021 12:00:00 EDT

Minimal Opioid Use After Total Hip Replacement (THR)

Condition:   Osteoarthritis, Hip
Interventions:   Procedure: Periarticular injection (Deep injection);   Procedure: Periarticular injection (Superficial injection);   Drug: Bupivacaine;   Drug: Placebo
Sponsor:   Hospital for Special Surgery, New York
Completed

Fri, 24 Mar 2017 12:00:00 EDT

An Evaluation of Pain Outcomes of Ketorolac Administration in Children Undergoing Circumcision

Conditions:   Pain, Postoperative;   Phimosis;   Paraphimosis;   Balanitis
Interventions:   Drug: Bupivacain;   Drug: Sevoflurane;   Drug: Acetaminophen;   Drug: Ibuprofen;   Drug: Ketorolac
Sponsor:   Alberta Children's Hospital
Not yet recruiting

Mon, 30 Nov 2020 12:00:00 EST

Battlefield Acupuncture for Acute/Subacute Back Pain in the Emergency Department

Condition:   Low Back Pain, Mechanical
Interventions:   Device: Battlefield Acupuncture;   Drug: Acetaminophen;   Drug: Diclofenac;   Drug: Diazepam;   Drug: Hydrocodone;   Drug: Ketorolac
Sponsor:   San Antonio Military Medical Center
Completed

Tue, 25 Jun 2019 12:00:00 EDT

Evaluating Pain Outcomes of Ketorolac Administration in Children Undergoing Circumcision

Conditions:   Pain, Postoperative;   Phimosis;   Paraphimosis;   Balanitis
Interventions:   Drug: Bupivacaine;   Drug: Sevoflurane;   Drug: Acetaminophen;   Drug: Ibuprofen;   Drug: Ketorolac
Sponsor:   Alberta Children's Hospital
Completed

Mon, 28 Nov 2016 12:00:00 EST

Efficacy of Multimodal Peri- and Intraarticular Drug Injections in Total Knee Arthroplasty

Condition:   Osteoarthritis of the Knee
Interventions:   Drug: ropivacaine;   Drug: adrenaline;   Drug: ketorolac;   Drug: morphine;   Drug: fentanyl;   Drug: bupivacaine
Sponsor:   Asker & Baerum Hospital
Completed

Thu, 22 Nov 2007 12:00:00 EST

Intraoperative Floppy Iris Syndrome Undergoing Intraocular Lens Replacement Surgery

Conditions:   Intraocular Lens Replacement;   Intraoperative Floppy Iris Syndrome
Interventions:   Drug: Part 1 OMS302;   Drug: Part 2 OMS302;   Drug: Part 2 Placebo
Sponsor:   Omeros Corporation
Terminated

Fri, 21 Mar 2014 12:00:00 EDT

Safety, Efficacy and Pharmacokinetics of OMS302 in Subjects Undergoing Intraocular Lens Replacement With Phacoemulsification

Condition:   Intraocular Lens Replacement
Interventions:   Drug: OMS302;   Drug: Placebo
Sponsor:   Omeros Corporation
Completed

Wed, 18 Apr 2012 12:00:00 EDT

Safety and Efficacy of OMS302 in Subjects Undergoing Intraocular Lens Replacement With Phacoemulsification

Condition:   Intraocular Lens Replacement
Interventions:   Drug: OMS302;   Drug: Placebo
Sponsor:   Omeros Corporation
Completed

Tue, 18 Oct 2011 12:00:00 EDT

Ketamine-ketorolac Versus Fentanyl- Ketorolac I.M in Children During Bone Marrow Biopsy

Condition:   Hematological Malignancy (Leukemia- Lymphoma)
Interventions:   Drug: ketamine-ketorolac;   Drug: fentanyl- ketorolac
Sponsor:   Mansoura University
Completed

Tue, 28 Aug 2018 12:00:00 EDT

Improving Pain Management and Long Term Outcomes Following High Energy Orthopedic Trauma (Pain Study)

Condition:   Orthopaedic Fractures
Interventions:   Drug: NSAID;   Drug: Gabapentinoids;   Drug: placebo
Sponsor:   Major Extremity Trauma Research Consortium
Completed

Tue, 12 Feb 2013 12:00:00 EST

Comparison of a Pain Pump Versus Injectable Medication for Analgesia in Knee Arthroscopy

Condition:   Pain
Interventions:   Device: pain pump containing ropivacaine;   Device: saline pain pump with injectable medication;   Drug: ropivacaine, ketorolac , morphine sulfate
Sponsor:   University of South Alabama
Completed

Wed, 17 Nov 2010 12:00:00 EST

Acupuncture for Postoperative Nausea and Vomiting in Patients Undergoing Colorectal Surgery

Conditions:   Postoperative Nausea and Vomiting;   Colorectal Neoplasms
Interventions:   Procedure: High-dose acupuncture with intravenous infusion of ramosetron;   Device: P6 stimulation with intravenous infusion of ramosetron;   Drug: Intravenous infusion of ramosetron
Sponsors:   Pusan National University Yangsan Hospital;   Korea Institute of Oriental Medicine;   Korean Medicine Hospital of Pusan National University
Completed

Mon, 27 Jul 2015 12:00:00 EDT

Nonopioid Analgesia After Labral Surgery

Condition:   Narcotic Use
Interventions:   Drug: Celecoxib;   Drug: Hydrocodone-Acetaminophen;   Drug: Ketorolac;   Drug: Gabapentin;   Drug: Acetaminophen;   Drug: Diazepam
Sponsor:   Henry Ford Health System
Unknown status

Thu, 31 Jan 2019 12:00:00 EST

Nonopioid Analgesia After Arthroscopic Meniscus Surgery

Conditions:   Meniscus Disorder;   Narcotic Use
Interventions:   Drug: Celecoxib;   Drug: Hydrocodon/Acetaminophen;   Drug: Ketorolac;   Drug: Gabapentin;   Drug: Acetaminophen;   Drug: Diazepam
Sponsor:   Henry Ford Health System
Completed

Tue, 29 Jan 2019 12:00:00 EST

Nonopioid Analgesia After Anterior Cruciate Ligament Reconstruction

Condition:   Anterior Cruciate Ligament Injury
Interventions:   Drug: Celecoxib;   Drug: Hydrocodone-Acetaminophen;   Drug: Ketorolac;   Drug: Gabapentin;   Drug: Acetaminophen;   Drug: Diazepam
Sponsor:   Henry Ford Health System
Completed

Mon, 28 Jan 2019 12:00:00 EST

A Clinical Trial of Two Periarticular Multimodal Drug Injections in Total Hip and Knee Arthroplasty

Condition:   Total Hip and Knee Arthroplasty
Interventions:   Drug: Liposomal Bupivacaine;   Drug: Ropivacaine;   Drug: Bupivacaine;   Drug: Clonidine;   Drug: Ketorolac;   Drug: Epinephrine
Sponsor:   Kootenai Health
Completed

Mon, 07 Sep 2015 12:00:00 EDT

Role of Multimodal Analgesia in Decreasing Perioperative Pain in Tibial Plateau Fractures

Condition:   Tibial Plateau Fractures
Interventions:   Drug: Injection;   Drug: Injections
Sponsor:   University of Utah
Enrolling by invitation

Wed, 08 Sep 2021 12:00:00 EDT

Nitrous Oxide for Pain Management During In-office Transcervical Sterilization

Conditions:   Contraception;   Inhalation of Nitrous Oxide
Interventions:   Procedure: In-office Transcervical Sterilization (Essure®);   Drug: Standard Oral pain medications;   Drug: Intramuscular Ketorolac;   Drug: Placebo pills;   Other: Oxygen;   Other: Nitrous Oxide
Sponsors:   University of New Mexico;   Society of Family Planning;   Bayer
Completed

Tue, 09 Dec 2014 12:00:00 EST

Efficacy of Nefopam and Morphine in Balanced Analgesia for Acute Ureteric Colic

Condition:   Renal Colic
Interventions:   Drug: Ketorolac and nefopam balanced analgesia;   Drug: Balanced analgesia using ketorolac and morphine;   Drug: Pain control with single analgesics (ketorolac)
Sponsors:   Seoul National University Hospital;   Pharmbio Korea
Unknown status

Fri, 02 Mar 2012 12:00:00 EST

Multimodal Analgesia in Shoulder Arthroplasty

Conditions:   Shoulder Pain;   Opioid Use
Interventions:   Drug: Acetaminophen;   Drug: Celecoxib 200mg;   Drug: Celecoxib 400 mg;   Drug: Ropivacaine;   Drug: Ketorolac;   Drug: Acetaminophen Injectable Product;   Drug: Oxycodone;   Drug: Tramadol;   Drug: Morphine Injectable Solution;   Drug: hydrocodone bitartrate and acetaminophen;   Drug: Morphine;   Drug: Oxycodone Hydrochloride;   Drug: Meloxicam
Sponsor:   Rush University Medical Center
Withdrawn

Mon, 16 Jul 2018 12:00:00 EDT

Multimodal Narcotic Limited Perioperative Pain Control With Colorectal Surgery

Conditions:   Colon Cancer;   Colon Diverticulosis;   Colonic Neoplasms;   Colonic Diverticulitis;   Pain, Postoperative;   Ileus;   Ileus Paralytic;   Ileus; Mechanical;   Constipation Drug Induced;   Constipation;   Rectum Cancer;   Rectum Neoplasm
Interventions:   Drug: Acetaminophen;   Drug: Gabapentin;   Drug: Orphenadrine;   Drug: Lidocaine;   Drug: Marcaine;   Drug: Ketamine;   Drug: Methadone;   Drug: Tramadol;   Drug: Ketorolac;   Drug: Morphine Sulfate;   Drug: Fentanyl;   Drug: Dilaudid;   Drug: Hydrocodone-Acetaminophen Tab 5-325 MG;   Drug: HYDROCODONE/ACETAMINOPHEN 5 Mg-325 Mg ORAL TABLET
Sponsor:   University of Illinois College of Medicine at Peoria
Unknown status

Tue, 08 Nov 2016 12:00:00 EST

Dextromethorphan Use in Multimodal Analgesia Regimens for Total Knee Arthroplasty

Condition:   Pain, Postoperative
Interventions:   Drug: Dextromethorphan;   Drug: Placebo - Concentrate;   Drug: Acetaminophen;   Drug: Oxycodone;   Drug: Celecoxib;   Drug: Pantoprazole;   Drug: Ketorolac;   Drug: Gabapentin;   Drug: Hydromorphone
Sponsor:   University of Southern California
Terminated

Fri, 09 Dec 2016 12:00:00 EST

Risk of Hematoma After Ketorolac Use in Reduction Mammoplasty.

Conditions:   Breast Reduction;   Reduction Mammoplasty;   Hematoma;   Hemorrhage
Intervention:   Procedure: Hematoma
Sponsor:   McMaster University
Completed

Tue, 12 Sep 2017 12:00:00 EDT

Steroids in Total Knee Arthroplasty

Conditions:   Postoperative Pain;   Inflammation;   Osteoarthritis
Interventions:   Drug: Dexamethasone 10 mg;   Drug: Dexamethasone 20 mg;   Drug: Standard multimodal pain management regimen;   Drug: Placebo
Sponsor:   Emory University
Suspended

Tue, 19 Aug 2014 12:00:00 EDT

Effect of Postoperative Ketorolac on Bone Healing After Joint Fusion

Conditions:   Ketorolac;   Joint Fusion
Interventions:   Procedure: great toe (1st metatarsophalangeal joint) fusion;   Drug: IV Ketorolac;   Drug: Ketorolac Pill;   Drug: 5/325mg Oxycodone-Acetaminophen;   Drug: Aspirin 81Mg Ec Tab
Sponsor:   Rothman Institute Orthopaedics
Enrolling by invitation

Tue, 04 May 2021 12:00:00 EDT

Postoperative Analgesia After Total Knee Arthroplasty

Condition:   Arthroplasty, Replacement, Knee
Interventions:   Drug: Ropivacaine, Ketorolac, adrenaline;   Drug: Ropivacaine Ketorolac
Sponsor:   University of Aarhus
Terminated

Mon, 15 Jan 2007 12:00:00 EST

Trigger Point Injection for Myofascial Pain Syndrome in the Low Back: A Randomized Controlled Trial

Conditions:   Low Back Pain;   Myofascial Pain Syndrome Lower Back
Interventions:   Drug: Treatment of Myofascial Pain Syndrome in the low back. This intervention will be based on outcomes of the medications listed below.;   Drug: Evaluation of functional ability using a patient centered functional score known as the Modified Oswestry Disability Index (MODI). The intervention will be based on outcomes of medications below.;   Drug: Following up with participants 60-72 hours after treatment in the Emergency Department. This intervention will be based on outcomes of the medications listed below.
Sponsor:   Madigan Army Medical Center
Recruiting

Mon, 11 Jan 2021 12:00:00 EST

Effectiveness of Analgesia in Total Knee Arthroplasty

Condition:   Pain
Interventions:   Drug: several drugs: morphine chloride,ropivacaine,epinephrine,ketorolac;   Drug: ropivacaine,morphine chloride,epinephrine,ketorolac;   Drug: ropivacaine;   Drug: morphine ,ketorolac
Sponsor:   Jose Antonio Bernia Gil
Completed

Fri, 25 Feb 2011 12:00:00 EST