Full text biomedical articles
Drug management for acute tonicâclonic convulsions including convulsive status epilepticus in childrenAmy McTague, Timothy Martland, Richard Appleton, Cochrane Epilepsy Group
Cochrane Database Syst Rev. 2018 Jan; 2018(1): CD001905. Published online 2018 Jan 10. doi:Â 10.1002/14651858.CD001905.pub3
Population Pharmacokinetics and Exploratory Pharmacodynamics of Lorazepam in Pediatric Status EpilepticusDaniel Gonzalez, James M. Chamberlain, Jeffrey T. Guptill, Michael Cohen-Wolkowiez, Barrie Harper, Jian Zhao, Edmund V. Capparelli
Clin Pharmacokinet. Author manuscript; available in PMC 2018 Aug 1.
Published in final edited form as: Clin Pharmacokinet. 2017 Aug; 56(8): 941â951. doi:Â 10.1007/s40262-016-0486-0
GABAergic modulation with classical benzodiazepines prevent stress-induced neuro-immune dysregulation and behavioral alterationsKarol Ramirez, Anzela Niraula, John F. Sheridan
Brain Behav Immun. Author manuscript; available in PMC 2017 Jan 1.
Published in final edited form as: Brain Behav Immun. 2016 Jan; 51: 154â168. Published online 2015 Sep 3. doi:Â 10.1016/j.bbi.2015.08.011
Effects of lorazepam and baclofen on shortâ and longâlatency afferent inhibitionClaudia V. Turco, Jenin ElâSayes, Mitchell B. Locke, Robert Chen, Steven Baker, Aimee J. Nelson
J Physiol. 2018 Nov 1; 596(21): 5267â5280. Published online 2018 Oct 3. doi:Â 10.1113/JP276710
Drug therapy for delirium in terminally ill adultsAnne M Finucane, Louise Jones, Baptiste Leurent, Elizabeth L Sampson, Patrick Stone, Adrian Tookman, Bridget Candy, Cochrane Pain, Palliative and Supportive Care Group
Cochrane Database Syst Rev. 2020 Jan; 2020(1): CD004770. Published online 2020 Jan 21. doi:Â 10.1002/14651858.CD004770.pub3
Adverse performance effects of acute lorazepam administration in elderly long-term users: pharmacokinetic and clinical predictorsNunzio Pomara, Sang Han Lee, Davide Bruno, Timothy Silber, David J. Greenblatt, Eva Petkova, John J. Sidtis
Prog Neuropsychopharmacol Biol Psychiatry. Author manuscript; available in PMC 2016 Jan 2.
Published in final edited form as: Prog Neuropsychopharmacol Biol Psychiatry. 2015 Jan 2; 0: 129â135. Published online 2014 Sep 6. doi:Â 10.1016/j.pnpbp.2014.08.014
Anticonvulsant therapy for status epilepticusManya Prasad, Pudukode R Krishnan, Reginald Sequeira, Khaldoon AlâRoomi, Cochrane Epilepsy Group
Cochrane Database Syst Rev. 2014 Sep; 2014(9): CD003723. Published online 2014 Sep 10. doi:Â 10.1002/14651858.CD003723.pub3
Potential prediction of formulation performance in paediatric patients using biopharmaceutical tools and simulation of clinically relevant administration scenarios of nifedipine and lorazepamAnna C. Van der Vossen, Lidwien M. Hanff, Arnold G. Vulto, Nikoletta Fotaki
Br J Clin Pharmacol. 2019 Aug; 85(8): 1728â1739. Published online 2019 Jun 18. doi:Â 10.1111/bcp.13956
The central nervous system effects of the partial GABA-Aα2,3-selective receptor modulator AZD7325 in comparison with lorazepam in healthy malesXia Chen, Gabriël Jacobs, Marieke de Kam, Judith Jaeger, Jaakko Lappalainen, Paul Maruff, Mark A Smith, Alan J Cross, Adam Cohen, Joop van Gerven
Br J Clin Pharmacol. 2014 Dec; 78(6): 1298â1314. Published online 2014 Nov 20. doi:Â 10.1111/bcp.12413
Effect of Lorazepam With Haloperidol vs Haloperidol Alone on Agitated Delirium in Patients With Advanced Cancer Receiving Palliative Care: A Randomized Clinical TrialDavid Hui, Susan Frisbee-Hume, Annie Wilson, Seyedeh S. Dibaj, Thuc Nguyen, Maxine De La Cruz, Paul Walker, Donna S. Zhukovsky, Marvin Delgado-Guay, Marieberta Vidal, Daniel Epner, Akhila Reddy, Kimerson Tanco, Janet Williams, Stacy Hall, Diane Liu, Kenneth Hess, Sapna Amin, William Breitbart, Eduardo Bruera
JAMA. Author manuscript; available in PMC 2017 Oct 30.
Published in final edited form as: JAMA. 2017 Sep 19; 318(11): 1047â1056. doi:Â 10.1001/jama.2017.11468
Formulation and Optimization of Polymeric Nanoparticles for Intranasal Delivery of Lorazepam Using Box-Behnken Design: In Vitro and In Vivo EvaluationDeepak Sharma, Dipika Maheshwari, Gilphy Philip, Ravish Rana, Shanu Bhatia, Manisha Singh, Reema Gabrani, Sanjeev K. Sharma, Javed Ali, Rakesh Kumar Sharma, Shweta Dang
Biomed Res Int. 2014; 2014: 156010. Published online 2014 Jul 14. doi:Â 10.1155/2014/156010
Benzodiazepines for treatment of patients with delirium excluding those who are cared for in an intensive care unitYan Li, Jun Ma, Yinghui Jin, Nan Li, Rui Zheng, Wei Mu, Jiaying Wang, Jin Hua Si, Jing Chen, Hong Cai Shang, Cochrane Dementia and Cognitive Improvement Group
Cochrane Database Syst Rev. 2020 Feb; 2020(2): CD012670. Published online 2020 Feb 28. doi:Â 10.1002/14651858.CD012670.pub2
Lorazepam challenge for individuals at varying genetic risk for Alzheimerâs diseaseCynthia M. Stonnington, Brian Harel, Dona E.C. Locke, Joseph G. Hentz, Nan Zhang, Paul Maruff, Richard J. Caselli
Alzheimer Dis Assoc Disord. Author manuscript; available in PMC 2018 Oct 1.
Published in final edited form as: Alzheimer Dis Assoc Disord. 2017 Oct-Dec; 31(4): 271â277. doi:Â 10.1097/WAD.0000000000000200
Pharmacokinetic Evaluation of Intranasally Administered Vinyl Polymer-Coated Lorazepam Microparticles in RabbitsYanjun Zhao, Marc B. Brown, Rajeshree H. Khengar, Matthew J. Traynor, Pedro Barata, Stuart A. Jones
AAPS J. 2012 Jun; 14(2): 218â224. Published online 2012 Mar 1. doi:Â 10.1208/s12248-012-9325-x
Dissociated effects of diazepam and lorazepam on short-latency afferent inhibitionVincenzo Di Lazzaro, Fabio Pilato, Michele Dileone, Pietro A Tonali, Ulf Ziemann
J Physiol. 2005 Nov 15; 569(Pt 1): 315â323. Published online 2005 Sep 1. doi:Â 10.1113/jphysiol.2005.092155
Comparative population pharmacokinetics of lorazepam and midazolam during long-term continuous infusion in critically ill patientsEleonora L Swart, Klaas P Zuideveld, Joost de Jongh, Meindert Danhof, Lambertus G Thijs, Robert M J Strack van Schijndel
Br J Clin Pharmacol. 2004 Feb; 57(2): 135â145. doi:Â 10.1046/j.1365-2125.2003.01957.x
Effects of lorazepam on short latency afferent inhibition and short latency intracortical inhibition in humansV Di Lazzaro, A Oliviero, E Saturno, M Dileone, F Pilato, R Nardone, F Ranieri, G Musumeci, T Fiorilla, P Tonali
J Physiol. 2005 Apr 15; 564(Pt 2): 661â668. Published online 2005 Feb 17. doi:Â 10.1113/jphysiol.2004.061747
Haloperidol plus promethazine for psychosisâinduced aggressionGisele Huf, Jacob Alexander, Pinky Gandhi, Michael H Allen, Cochrane Schizophrenia Group
Cochrane Database Syst Rev. 2016 Nov; 2016(11): CD005146. Published online 2016 Nov 25. doi:Â 10.1002/14651858.CD005146.pub3
Pharmacokinetic-pharmacodynamic analysis of mnesic effects of lorazepam in healthy volunteersO Blin, A Jacquet, S Callamand, E Jouve, M Habib, D Gayraud, A Durand, B Bruguerolle, P Pisano
Br J Clin Pharmacol. 1999 Oct; 48(4): 510â512. doi:Â 10.1046/j.1365-2125.1999.00047.x
The pharmacokinetics of intravenous lorazepam in pediatric patients with and without status epilepticusJames M. Chamberlain, Edmund V. Capparelli, Kathleen M. Brown, Cheryl W. Vance, Kathleen Lillis, Prashant Mahajan, Richard Lichenstein, Rachel M. Stanley, Colleen O. Davis, Stephen Gordon, Jill M. Baren, John N. van den Anker
J Pediatr. Author manuscript; available in PMC 2013 Apr 1.
Published in final edited form as: J Pediatr. 2012 Apr; 160(4): 667â672.e2. Published online 2011 Nov 1. doi:Â 10.1016/j.jpeds.2011.09.048
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