Clinical Trials
Spinal Morphine for Patients With Obstructive Sleep ApneaCondition: Obstructive Sleep ApneaInterventions: Drug: Intrathecal Morphine; Drug: No Intrathecal Morphine Sponsor: University Health Network, Toronto Suspended Wed, 13 Feb 2013 12:00:00 EST Morphine in Moderate Obstructive Sleep ApnoeaCondition: Obstructive Sleep ApnoeaIntervention: Drug: Morphine sulphate Sponsor: Papworth Hospital NHS Foundation Trust Terminated Tue, 25 Apr 2017 12:00:00 EDT Nebulized Morphine in Chest Trauma Patients: A Prospective StudyCondition: Blunt Injury of ThoraxIntervention: Drug: Morphine (+) Sponsor: University Hospital, Mahdia Completed Mon, 09 Jul 2018 12:00:00 EDT A Comparison of Morphine and Morphine Plus Dexmedetomidine in Chronic Cancer PainCondition: Chronic PainInterventions: Drug: Morphine; Drug: Morphine plus dexmedetomidine Sponsor: Cukurova University Completed Thu, 13 Nov 2014 12:00:00 EST Comparison for Pethidine Requirement in Patients Received Spinal Morphine 0.2 and 0.3 mg for Post Lobectomy AnalgesiaConditions: Solitary Mass; Lung DiseasesInterventions: Drug: spinal morphine 0.3 mg; Drug: spinal morphine 0.2 mg Sponsor: Mahidol University Completed Mon, 08 Nov 2010 12:00:00 EST The Effect of Neuraxial Morphine (Duramorph) on Pain ControlCondition: Perineal TearIntervention: Drug: Morphine. Sponsor: Augusta University Recruiting Wed, 24 Apr 2019 12:00:00 EDT Intravenous Remifentanil Plus Morphine or Morphine Alone for Postthoracotomy PainCondition: PainIntervention: Drug: Remifentanil+morphine Sponsor: Cukurova University Completed Fri, 12 Apr 2013 12:00:00 EDT Optimal Morphine Dosing Schedule for Neonatal Abstinence SyndromeConditions: Neonatal Abstinence Syndrome; Neonatal Opioid Withdrawal; Neonatal Opioid Withdrawal SyndromeInterventions: Drug: Morphine PRN; Drug: Morphine scheduled Sponsor: Indiana University Recruiting Fri, 06 Mar 2020 12:00:00 EST Effect of Intrathecal Morphine in Children Undergoing Major Abdominal Surgeries,Condition: Major Abdominal SurgeriesIntervention: Drug: Intrathecal Morphine Sponsor: Assiut University Unknown status Thu, 18 May 2017 12:00:00 EDT Therapeutic Rest to Delay Admission in Early Labor: A Prospective Study on Morphine SleepConditions: Labor Pain; Early LaborIntervention: Drug: Morphine Sulfate and Promethazine Sponsor: University of California, San Francisco Completed Tue, 29 May 2018 12:00:00 EDT 
Acupuncture Versus Intravenous Morphine in the Management of Acute Pain in the Emergency DepartmentCondition: Acute PainInterventions: Procedure: Acupuncture; Drug: Morphine titration Sponsor: University of Monastir Completed Wed, 03 Jun 2015 12:00:00 EDT Evaluation of Risk Minimization, Assessment and Outcomes in Patients With Chronic Pain Taking AvinzaCondition: PainIntervention: Drug: morphine sulfate extended release capsules Sponsor: Pfizer Completed Thu, 20 Mar 2008 12:00:00 EDT Ultrasound Guided QLB III Versus Intrathecal Morphine for Analgesia After Cesarean SectionCondition: BlockInterventions: Drug: Morphine; Drug: Quadratus lumborum block Sponsor: University Tunis El Manar Completed Mon, 12 Feb 2018 12:00:00 EST Association Between Clinical Effect of Morphine With PCA After Surgery and PharmacogeneticsConditions: Anesthesia; SurgeryIntervention: Drug: morphine chlorhydrate Sponsor: IRCCS Policlinico S. Matteo Completed Wed, 03 Nov 2010 12:00:00 EDT Is Analgesic Effect of Low Dose Ketamine-midazolam the Same as MorphineCondition: Closed Multiple Fractures of Upper and Lower LimbsInterventions: Drug: Ketamine-midazolam; Drug: Morphine Sponsor: Isfahan University of Medical Sciences Completed Fri, 08 Mar 2013 12:00:00 EST Intrathecal Morphine Versus Epidural Extended Release Morphine for Pediatric Patients Undergoing Spinal FusionConditions: Pain Management; Spinal Fusion; ScoliosisInterventions: Drug: Intrathecal morphine; Drug: Extended Release Epidural Morphine Sponsor: University of Colorado, Denver Completed Tue, 14 Apr 2009 12:00:00 EDT Effect of Locally Administered Morphine and Bupivicaine on Acute and Chronic Postmastectomy PainConditions: Acute Pain; Chronic PainIntervention: Drug: local instillation of morphine to surgical wound Sponsor: Assiut University Completed Thu, 04 Jun 2015 12:00:00 EDT Intraosseous Morphine in Primary TKAConditions: Knee Disease; Arthritis Knee; Pain, AcuteIntervention: Drug: Morphine Sponsor: The Methodist Hospital Research Institute Completed Thu, 14 May 2020 12:00:00 EDT Comparing the Analgesic Effect of Intravenous Acetaminophen and Morphine on Patients With Renal Colic Pain Reffering to the Emergency Department: A Randomized Controlled TrialCondition: Renal ColicInterventions: Drug: Acetaminophen; Drug: Morphine Sponsor: Seyed Mehdi Pourafzali Completed Wed, 24 Jul 2013 12:00:00 EDT Trial Comparing Intrathecal Morphine With Placebo In Patients Undergoing Robotic Cardiac SurgeryCondition: PainInterventions: Drug: Intrathecal morphine; Drug: Placebo Sponsor: University of Chicago Completed Mon, 07 Aug 2017 12:00:00 EDT
Development of a Morphine Pharmacokinetic and Pharmacodynamic Model for the Neonatal PopulationConditions: Pain; Drug EffectIntervention: Drug: Morphine Sponsor: The Hospital for Sick Children Withdrawn Mon, 30 Jan 2017 12:00:00 EST Study to Examine Pain Relief With Supplemental Intrathecal Morphine in TKA PatientsCondition: Acute PainInterventions: Drug: Morphine; Drug: Placebo Sponsor: Stony Brook University Unknown status Thu, 03 Dec 2015 12:00:00 EST The Effect of Adding Nalbuphine to Intrathecal Morphine on Analgesic Efficacy and Side Effects After Cesarean SectionCondition: Postoperative PainInterventions: Drug: Morphine; Drug: Morphine plus Nalbuphine Sponsor: Abdelrady S Ibrahim, MD Completed Wed, 23 Mar 2016 12:00:00 EDT Oxcarbazepine Plus Morphine in Patients With Refractory Cancer PainCondition: CancerInterventions: Drug: Morphine; Drug: Oxcarbazepine Sponsor: Costantine Albany Terminated Wed, 05 Mar 2014 12:00:00 EST Morphine In Acute Myocardial InfarctionCondition: Acute Myocardial InfarctionInterventions: Drug: morphine chlorhydrate; Drug: saline solution Sponsors: French Cardiology Society; Institut National de la Santé Et de la Recherche Médicale, France Completed Mon, 23 Aug 2010 12:00:00 EDT Titrated Versus High and Low Dose Nebulized Morphine to Reduce Pain in Emergency SettingsConditions: Post-Traumatic Headache; Acute PainInterventions: Drug: IV titrated morphine; Drug: Low dose nebulised morphine; Drug: High dose nebulised morphine Sponsor: University of Monastir Completed Fri, 25 Jul 2014 12:00:00 EDT Spinal Morphine for Postoperative Analgesia in UrologyCondition: Pain, PostoperativeIntervention: Drug: Morphine Sponsor: Charles University, Czech Republic Completed Tue, 18 Sep 2018 12:00:00 EDT Treatment of Neonatal Abstinence Syndrome With Clonidine Versus Morphine as Primary TherapyCondition: Neonatal Abstinence SyndromeInterventions: Drug: Clonidine; Drug: Morphine Sulfate Sponsor: The Cooper Health System Recruiting Mon, 27 Mar 2017 12:00:00 EDT 0.15 mg Spinal Morphine vs. no Treatment for Morphine Requirement After VATs.Condition: Postoperative PainIntervention: Drug: Spinal morphine Sponsor: Mahidol University Unknown status Fri, 08 Nov 2013 12:00:00 EST Comparative Bioavailability Study of Morphine Sulfate Immediate Release and Controlled ReleaseCondition: PainIntervention: Drug: morphine sulfate Sponsor: Roxane Laboratories Completed Wed, 14 Oct 2009 12:00:00 EDT
Spinal Morphine Provides an Effective Pain Control in Patients Undergoing Transurethral Resection of Prostate GlandConditions: Spinal Anesthesia; Transurethral Resection of Prostate; AnalgesiaInterventions: Drug: Morphine; Drug: Placebo Sponsor: Mahidol University Completed Mon, 01 Jun 2015 12:00:00 EDT Evaluation of Peripheral Itch Mechanisms Following Injection of MorphineConditions: Morphine; Histamine; Cowhage; Isotonic SalineIntervention: Drug: Morphine Sponsor: Aalborg University Recruiting Thu, 17 Dec 2020 12:00:00 EST 0.05 mg Versus 0.1 mg Spinal Morphine for Reducing Morphine Requirement After Vaginal HysterectomyCondition: PainIntervention: Drug: Morphine Sponsor: Mahidol University Unknown status Thu, 04 Mar 2010 12:00:00 EST Morphine Versus Morphine-promethazine Combination for Acute Low Back Pain Relief in the Adult Emergency DepartmentCondition: Low Back PainInterventions: Drug: Morphine-Promethazine; Drug: morphine Sponsor: Tel-Aviv Sourasky Medical Center Unknown status Tue, 25 May 2010 12:00:00 EDT 0.05 Versus 0.1 mg Spinal Morphine for Reducing Morphine Requirement After Vaginal HysterectomyConditions: Pain; Vaginal HysterectomyInterventions: Drug: Spinal morphine 0.05 mg; Drug: Spinal morphine 0.1 mg Sponsor: Mahidol University Unknown status Wed, 03 Mar 2010 12:00:00 EST Efficacy of Injectable Fentanyl in Sublingual Route Versus Oral Morphine Syrup for Breakthrough PainCondition: Pain, BreakthroughInterventions: Drug: Fentanyl Citrate 50Mcg/Ml Inj_#1; Drug: Morphine Sponsor: Rajavithi Hospital Recruiting Wed, 08 Sep 2021 12:00:00 EDT Genetic Variation in Organic Cation Transport 1 (OCT1) and Its Significance for Morphine PharmacokineticsConditions: Organic Cation Transporter 1; MorphineIntervention: Drug: Morphine Sponsors: University of Southern Denmark; Danish Council for Independent Research; The Faculty of Health Sciences SDU; Region of Southern Denmark Completed Wed, 07 Feb 2018 12:00:00 EST Intravenous Lidocaine Versus Morphine for Severe Pain in the EDCondition: PainInterventions: Drug: Intravenous lidocaine; Drug: Intravenous morphine Sponsor: Alameda Health System Completed Fri, 23 Sep 2016 12:00:00 EDT Spinal Morphine vs. Hydromorphone for Pain Control After Cesarean DeliveryConditions: Analgesia, Obstetrical; Obstetric Surgical ProceduresInterventions: Drug: Morphine; Drug: Hydromorphone Sponsor: Mayo Clinic Completed Fri, 03 Jun 2016 12:00:00 EDT Adding Nalbuphine for Control of Intrathecal Morphine PruritusConditions: Pruritus; Pain, Postoperative; Nausea, Postoperative; Vomiting, PostoperativeInterventions: Drug: Morphine 10 MG/ML; Drug: Nalbuphine Hydrochloride 10 MG/ML Sponsor: Minia University Recruiting Mon, 19 Oct 2020 12:00:00 EDT
Association Between Clinical Effect of Continuous Morphine Administration After Surgery and PharmacogeneticsConditions: Anesthesia; SurgeryIntervention: Drug: morphine chlorhydrate Sponsor: IRCCS Policlinico S. Matteo Withdrawn Wed, 03 Nov 2010 12:00:00 EDT Intranasal Fentanyl Versus Intravenous Morphine in the Treatment of Severe Painful Sickle Cell Crises in ChildrenConditions: Pain; Sickle Cell DiseaseInterventions: Drug: Fentanyl Citrate; Drug: Morphine sulphate Sponsors: University College Dublin; National Children's Research Centre; Our Lady's Children's Hospital, Crumlin Completed Mon, 24 Sep 2018 12:00:00 EDT Labour Analgesia; Comparing a Combinations of Either Fentanyl or Bupivacaine With Intrathecal MorphineCondition: Labor PainInterventions: Drug: Intrathecal morphine with fentanyl; Drug: Intrathecal morphine with bupivacaine Sponsor: Makerere University Completed Wed, 15 Jul 2015 12:00:00 EDT Epidural Morphine Following Vaginal DeliveryCondition: PainInterventions: Drug: Preservative-free epidural morphine; Drug: Placebo Sponsors: Mount Sinai Hospital, Canada; The Physicians' Services Incorporated Foundation Completed Fri, 05 Dec 2008 12:00:00 EST Effect of Morphine on Dyspnea and 6-Minute Walk Distance in Pulmonary Arterial HypertensionCondition: Pulmonary Arterial HypertensionIntervention: Drug: Morphine Sulfate Sponsor: John Granton Unknown status Wed, 17 Jan 2018 12:00:00 EST Ibuprofen Compared to Morphine as a Pediatric Postoperative Pain Management Tool Following Inguinal SurgeryCondition: Inguinal SurgeryInterventions: Drug: Ibuprofen; Drug: Morphine Sponsors: McMaster University; McMaster Surgical Associates Recruiting Fri, 13 Nov 2015 12:00:00 EST Study of Oral Morphine Sulfate Administration in Pediatric SubjectsCondition: Pain, PostoperativeIntervention: Drug: Morphine Sulfate Sponsors: West-Ward Pharmaceutical; Premier Research International LLC Completed Mon, 12 Feb 2018 12:00:00 EST Efficacy Study of Nebulized Morphine and Intravenous Morphine in Post Traumatic PainCondition: Post Traumatic PainInterventions: Drug: nebulized morphine; Drug: Intravenous morphine Sponsor: University of Monastir Completed Fri, 14 May 2010 12:00:00 EDT Epidural Morphine Versus Epidural Fentanyl Infusion Following Cesarean SectionCondition: PainInterventions: Drug: Preservative free morphine; Drug: Fentanyl Sponsor: Goodman, Evan, M.D. Unknown status Wed, 01 Jun 2011 12:00:00 EDT Decreased Neuraxial Morphine After Cesarean DeliveryCondition: AnesthesiaInterventions: Drug: Morphine Sulfate 150 mcg; Drug: Morphine Sulfate 50mcg Sponsor: University of Alabama at Birmingham Recruiting Thu, 20 Feb 2020 12:00:00 EST
Randomized, Double-blind, Placebo, Controlled Cross Over Design Topical Morphine for Analgesia in Pediatric ProceduresCondition: PainInterventions: Drug: Topic Morphine; Drug: Placebo Sponsor: Hospital General de Niños Pedro de Elizalde Withdrawn Mon, 24 Nov 2014 12:00:00 EST Serum Serotonin and Pruritus After Intrathecal Morphine in Cesarean SectionCondition: PruritusInterventions: Drug: Morphine 100 μg; Drug: Morphine 200 μg Sponsor: Assiut University Completed Thu, 06 Jul 2017 12:00:00 EDT Methadone Versus Morphine for Cancer-Related PainConditions: Neoplasms; PainInterventions: Drug: Methadone; Drug: Morphine Sponsor: Mayo Clinic Terminated Fri, 14 Dec 2007 12:00:00 EST The Median Effective Dose (ED50) of Paracetamol and Morphine : A Study of Interaction StudyCondition: Postoperative PainInterventions: Drug: Paracetamol; Drug: Morphine; Drug: Paracetamol- Morphine Sponsor: Procare Riaya Hospital Completed Mon, 06 Jun 2011 12:00:00 EDT Safety and Pharmacokinetic Study of Oral Morphine Sulfate in Pediatric SubjectsCondition: PainIntervention: Drug: Morphine Sulfate Sponsor: Roxane Laboratories Completed Thu, 24 Mar 2011 12:00:00 EDT Sleep Apnea and Obesity Affects on Morphine PharmacokineticsConditions: Pediatric Sleep Apnea; Obesity; Morphine MetabolismIntervention: Other: Morphine pharmacokinetic evaluation Sponsor: Johns Hopkins University Completed Mon, 11 Apr 2016 12:00:00 EDT Oxycodone Versus Intravenous Morphine for Postoperative Analgesia After Hip SurgeryCondition: Arthroplasty, Replacement, HipInterventions: Drug: Standard Care morphine hydrochloride; Drug: Oxycodone Sponsor: Centre Hospitalier Universitaire de Nīmes Completed Wed, 22 Feb 2012 12:00:00 EST Slow-Release Oral Morphine for the Treatment of Opioid Use DisorderConditions: Opioid-Related Disorders; Opiate Substitution Treatment; Morphine; Methadone; FentanylInterventions: Drug: Slow release oral morphine (SROM); Drug: Methadone Sponsors: M. Eugenia Socias; Canadian Institutes of Health Research (CIHR); Vancouver Foundation; Mayne Pharma International Pty Ltd Suspended Tue, 14 May 2019 12:00:00 EDT Low Dose Ketamine (LDK) Versus Morphine for Acute Pain Control in the Emergency DepartmentConditions: Abdomen, Acute; Other Acute Pain; Flank Pain; Back Pain; Musculoskeletal PainInterventions: Drug: Ketamine; Drug: Morphine Sponsors: Brooke Army Medical Center; U.S. Air Force Office of the Surgeon General Completed Fri, 24 Feb 2012 12:00:00 EST An Interventional Study for Patient With Cancer Pain to Evaluate the Efficacy and Safety of OxyNorm® Compared to Morphine Sulfate Through the IV Continuous Infusion.Condition: Cancer PainInterventions: Drug: Oxycodone Hydrochloride; Drug: Morphine Sulphate Sponsor: Mundipharma Korea Ltd Completed Thu, 21 Jan 2016 12:00:00 EST
Impact of Epidural Morphine on Shoulder Pain Following Thoracotomy.Conditions: Postoperative Pain; Shoulder PainInterventions: Drug: Fentanyl; Drug: Morphine Sponsor: Centre hospitalier de l'Université de Montréal (CHUM) Terminated Thu, 14 Nov 2013 12:00:00 EST Enhanced Recovery After Cesarean Section With Low Dose Intrathecal Morphine.Conditions: Pain, Postoperative; Pruritus; Nausea, Postoperative; Vomiting, PostoperativeInterventions: Drug: Morphine Sulfate; Drug: Bupivacaine Hydrochloride Sponsor: Minia University Recruiting Thu, 05 Nov 2020 12:00:00 EST Intrathecal Morphine for Cesarean DeliveryCondition: Postoperative PainIntervention: Drug: Morphine Sulfate Sponsor: Beth Israel Deaconess Medical Center Not yet recruiting Wed, 06 Oct 2021 12:00:00 EDT Low-dose Ketamine vs Morphine for Vaso-occlusive Crisis in SicklersConditions: Sickle Cell Crisis; Acute PainInterventions: Drug: Low dose ketamine; Drug: Morphine Sponsor: Makerere University Completed Wed, 06 May 2015 12:00:00 EDT Comparative Study to Evaluate KADIAN and Avinza in Healthy AdultsCondition: HealthyInterventions: Drug: KADIAN (morphine sulfate sustained-release) capsules; Drug: Avinza (morphine sulfate sustained-release) capsules Sponsor: Actavis Inc. Completed Fri, 31 Oct 2008 12:00:00 EDT Effect of Mu-opioid Receptor Genetics on 3 Doses of Spinal Morphine for Postoperative Analgesia After Cesarean SectionCondition: Postoperative PainIntervention: Drug: Morphine Sponsor: Columbia University Completed Fri, 04 Nov 2011 12:00:00 EDT Effect of Tramadol Versus Morphine on PD1 and PD1-ligand in Patients With Chronic Cancer PainCondition: Chronic PainIntervention: Drug: Tramadol Hydrochloride Sponsor: Assiut University Recruiting Mon, 19 Oct 2020 12:00:00 EDT Comparison of 0.1 and 0.05mg Intrathecal Morphine for Post-cesarean Analgesia.Condition: Cesarean SectionInterventions: Drug: receiving 0.1 mg IT morphine; Drug: recieving 0.05 mg IT morphine Sponsor: Medical University of South Carolina Recruiting Fri, 09 Feb 2018 12:00:00 EST TAP Block With Intrathecal Fentanyl vs. Intrathecal Morphine in Cesarean DeliveryCondition: Cesarean SectionInterventions: Drug: fentanyl; Drug: morphine; Procedure: Transversus abdominis plane block; Procedure: Sham block Sponsor: Seoul National University Hospital Recruiting Thu, 01 Apr 2021 12:00:00 EDT Morphine PK Subgroup AnalysisCondition: Post Operative PainIntervention: Drug: Morphine Sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Completed Thu, 24 Mar 2011 12:00:00 EDT
Bioequivalence Study of Morphine Sulfate 60 mg Extended-Release Tablets Under Fed ConditionsCondition: HealthyIntervention: Drug: Morphine Sulfate Sponsor: Ranbaxy Inc. Completed Wed, 15 Aug 2012 12:00:00 EDT Bioequivalence Study of Morphine Sulfate 60 mg Extended-Release Tablets Under Fasting ConditionsCondition: HealthyIntervention: Drug: Morphine Sulfate Sponsor: Ranbaxy Inc. Completed Wed, 15 Aug 2012 12:00:00 EDT Effects of Morphine on Loading-dose Ticagrelor in Patients With ST-segment Elevation Myocardial InfarctionCondition: ST-segment Elevation Myocardial InfarctionInterventions: Drug: Morphine; Drug: metoclopramide; Drug: saline Sponsor: General Hospital of Chinese Armed Police Forces Recruiting Fri, 23 Sep 2016 12:00:00 EDT Comparing Intrathecal Morphine and Intraoperative Lidocaine Infusion to Epidural Anesthesia With Postoperative PCA for Patients Undergoing Exploratory LaparotomyConditions: Cancer Debulking; Enlarged Uterus; Fibroid Uterus; Adnexal MassInterventions: Drug: Bupivacaine; Drug: Morphine; Drug: Lidocaine Sponsors: Washington University School of Medicine; The Foundation for Barnes-Jewish Hospital Not yet recruiting Mon, 23 Aug 2021 12:00:00 EDT Bioequivalency Study of Morphine Sulfate Injection, Solution and Tablet Under Fasted ConditionsCondition: PainIntervention: Drug: morphine sulfate Sponsor: Roxane Laboratories Completed Wed, 14 Oct 2009 12:00:00 EDT Ketamine Associated With Morphine PCA After Total Hip ArthroplastyCondition: Arthroplasty, Replacement, HipInterventions: Drug: Ketamine-Morphine; Drug: Morphine; Drug: Postoperative PCA of Ketamine and morphine Sponsor: Assistance Publique - Hôpitaux de Paris Completed Tue, 25 Nov 2008 12:00:00 EST Intrathecal Morphine in Knee ArthroplastyConditions: Pain, Postoperative; Arthroplasty, Replacement, KneeIntervention: Drug: intra thecal morphine Sponsor: University College Hospital Galway Completed Wed, 11 Jun 2008 12:00:00 EDT Neurotoxic Adverse Effects of Morphine and Oxycodone for Pain in Terminal Patients With Diminished Renal FunctionConditions: Pain; Terminal Illness; Renal ImpairmentInterventions: Drug: Oxycodone; Drug: Morphine Sponsors: Maastricht University Medical Center; ZonMw: The Netherlands Organisation for Health Research and Development; Envida, Maastricht, The Netherlands Terminated Mon, 06 Aug 2018 12:00:00 EDT Intranasal Fentanyl Versus Oral Morphine Sulfate in the Treatment of Pain in Pediatric TraumaCondition: Pain, AcuteInterventions: Drug: Intranasal fentanyl + Oral Placebo; Drug: Oral Morphine + Intranasal Placebo Sponsor: University Hospital, Montpellier Terminated Fri, 24 Feb 2017 12:00:00 EST The Efficacy of Pain Control After Total Hip Replacement Between Ultrasound Guided Supra-inguinal Fascia Iliaca Block and Intrathecal MorphineConditions: Total Hip Replacement; Ultrasound Guided Supra-inguinal Fascia Iliaca Block; Intrathecal Morphine; Postoperative PainInterventions: Drug: Intrathecal morphine; Drug: Ultrasound guided supra-inguinal fascia iliaca block Sponsor: Mahidol University Recruiting Thu, 26 Sep 2019 12:00:00 EDT
The Effects of Morphine on Desflurane Consumption and Recovery TimeCondition: Abdominal Hysterectomy (& Wertheim)Intervention: Drug: Morphine Sponsor: Baskent University Completed Thu, 12 Feb 2015 12:00:00 EST Comparison of Treatment by IN Ketamine to IV Morphine in Acute PainCondition: Acute Traumatic PainInterventions: Drug: Morphine; Drug: Ketamine Sponsors: Tel-Aviv Sourasky Medical Center; Medical Corps, Israel Defense Force Not yet recruiting Mon, 30 Apr 2018 12:00:00 EDT Does Local Morphine Add to Local Anesthetics in Serratus Anterior Plane Block Has a System Analgesic Effect?Condition: Postoperative ComplicationsInterventions: Drug: Morphine Sulfate; Drug: Bupivacaine Hydrochloride Sponsor: Fatma Adel El sherif,MD Completed Fri, 11 Nov 2016 12:00:00 EST Low-dose Spinal Morphine for Post-Thoracotomy Pain After Video-Assisted Thoracoscopic SurgeryCondition: Video-assisted Thoracoscopic SurgeryInterventions: Drug: Morphine; Other: control Sponsor: Mahidol University Completed Tue, 06 Aug 2013 12:00:00 EDT Intrathecal Morphine Analgesia vs. Continuous Epidural Analgesia vs. Systemic Analgesia in Colorectal Surgery.Conditions: Analgesia, Patient-Controlled; Epidural Analgesia; Anesthesia; Spinal; Morphine; Surgery, Colorectal; Intravenous Drug Delivery SystemsInterventions: Drug: Morphine intrathecal; Drug: Bupivacaine + Sufentanil epidural; Drug: Morphine intravenous Sponsor: Charles University, Czech Republic Completed Mon, 02 Jan 2017 12:00:00 EST Two Dose Epidural Morphine for Post-cesarean AnalgesiaConditions: Pain; Morphine Adverse ReactionInterventions: Drug: Epidural Morphine; Drug: Epidural Saline Sponsor: Columbia University Terminated Wed, 01 May 2013 12:00:00 EDT Effectiveness of Controlled-Release Morphine for Chronic Neuropathic Pain After Spinal Cord InjuryConditions: Neuropathic Pain; Spinal Cord InjuryInterventions: Drug: Modified-release morphine; Drug: Placebo Sponsors: Icahn School of Medicine at Mount Sinai; U.S. Department of Education Completed Wed, 20 Jun 2007 12:00:00 EDT Morphine Versus Ketorolac in Renal ColicCondition: Renal ColicInterventions: Drug: Ketorolac; Drug: Morphine Sponsor: Loredana Ghinea Unknown status Wed, 25 May 2016 12:00:00 EDT TAP Catheters Versus Intrathecal Morphine for Cesarean SectionConditions: Abdominal Muscles/Ultrasonography; Adult; Anesthetics, Local/Administration & Dosage; Ropivacaine/Administration & Dosage; Ropivacaine/Analogs & Derivatives; Cesarean Section; Humans; Nerve Block/Methods; Pain Measurement/Methods; Pain, Postoperative/Prevention & Control; Ultrasonography, InterventionalInterventions: Device: TAP catheter; Drug: intrathecal morphine Sponsors: Stamford Anesthesiology Services, PC; I-Flow Unknown status Tue, 08 May 2012 12:00:00 EDT Morphine Versus Ketorolac in Low Back PainCondition: Low Back PainInterventions: Drug: Ketorolac; Drug: Morphine Sponsor: Loredana Ghinea Unknown status Wed, 25 May 2016 12:00:00 EDT
Randomized, Controlled, Double Blind, to Evaluate the Postpartum Analgesia With Epidural Morphine: Analgesic Effect of Two Different Doses Compared to PlaceboCondition: Labor PainInterventions: Drug: Morphine; Drug: saline solution Sponsor: Universidad Nacional de Colombia Completed Fri, 14 May 2021 12:00:00 EDT Methadone Associated With Morphine for Cancer PainCondition: CancerInterventions: Drug: Morphine; Drug: Methadone Sponsor: Federal University of São Paulo Unknown status Mon, 30 Oct 2017 12:00:00 EDT Morphine Modulation of The Brain's Pain MatrixCondition: PainInterventions: Drug: Morphine; Other: orange juice Sponsor: University of Aarhus Completed Mon, 22 Nov 2010 12:00:00 EST 2 Dose Neuraxial Morphine for Prevention of PDPHCondition: Postdural Puncture HeadacheInterventions: Drug: Morphine; Drug: Sterile normal saline Sponsor: Columbia University Recruiting Tue, 16 Jun 2015 12:00:00 EDT Evaluation of Oral Morphine Gel in Oral Mucositis Induced by Chemotherapy in Children and Young AdultsCondition: CancerInterventions: Drug: morphine gel; Drug: placebo gel Sponsor: University Hospital, Strasbourg, France Unknown status Wed, 25 Jun 2014 12:00:00 EDT Efficacy of Topical Morphine in the Treatment of Severe Local Pain of Chronic WoundsConditions: Local Pain; Chronic WoundsInterventions: Drug: Morphine gel; Other: Neutral gel Sponsors: Institut Curie; Assistance Publique - Hôpitaux de Paris; Hôpital Louis Mourier Terminated Tue, 07 Jan 2014 12:00:00 EST Comparison of Buprenorphine to Morphine in Treatment of Neonatal Abstinence Syndrome (NAS)Conditions: Neonatal Abstinence Syndrome; Neonatal Withdrawal SyndromeInterventions: Drug: Buprenorphine; Drug: Morphine Sulfate Sponsor: Mednax Center for Research, Education, Quality and Safety Completed Wed, 17 Oct 2012 12:00:00 EDT Intraoperative Methadone vs Morphine for Postoperative Pain Control in Patients Undergoing Surgery of the TibiaCondition: Pain, PostoperativeInterventions: Drug: Methadone; Drug: Morphine Sponsor: Baylor College of Medicine Terminated Thu, 08 Sep 2011 12:00:00 EDT Effect of Local Administration of Morphine for Analgesia After Iliac Bone Graft HarvestCondition: Autogenous Bone GraftsIntervention: Drug: morphine Sponsors: The Cleveland Clinic; Haydarpasa Numune Training and Research Hospital Withdrawn Wed, 23 Dec 2009 12:00:00 EST Validation of an Observational Scale of Dyspnea in Non-communicating Patients in the ICUCondition: DyspneaIntervention: Drug: Morphine Sponsor: Association pour le Développement et l'Organisation de la Recherche en Pneumologie et sur le Sommeil Completed Thu, 16 Jun 2016 12:00:00 EDT
Ketamine Versus Morphine Change Pain ProfileCondition: Acute PainInterventions: Drug: Ketamine; Drug: Morphine Sponsor: Cairo University Completed Mon, 10 Sep 2018 12:00:00 EDT Post Operative Pain Control: Morphine vs FentanylCondition: Post Operative AnalgesiaInterventions: Drug: Morphine; Drug: Fentanyl Sponsor: Catholic University of the Sacred Heart Completed Mon, 26 May 2014 12:00:00 EDT Morphine or Fentanyl for Refractory Dyspnea in COPDCondition: COPDInterventions: Drug: Fentanyl; Drug: Morphine Retard; Drug: Placebo patch; Drug: Placebo oral capsule Sponsors: Huib A.M. Kerstjens; Dutch Foundation for Asthma Prevention; Innovatiefonds Zorgverzekeraars Recruiting Thu, 07 Feb 2019 12:00:00 EST Study to Assess Pharmacokinetic (PK), Bioavailability & Food Effect of MR902 Compared With Immediate Release (IR) Morphine Sulphate Oral SolutionCondition: Opioid Substitution TreatmentInterventions: Drug: MR902; Drug: IR morphine sulphate Sponsor: Mundipharma Research Limited Completed Mon, 16 May 2016 12:00:00 EDT Pre-hospital Morphine Titration : Comparison of 0,05 Versus 0,1 mg/kgCondition: Severe, Acute Pain in a Pre-hospital SettingIntervention: Drug: morphine Sponsor: University Hospital, Toulouse Completed Wed, 12 Oct 2005 12:00:00 EDT Comparison Between Pericapsular Nerve Group Block (PENG) and Morphine InfusionConditions: Analgesia; Femur FractureInterventions: Procedure: Pericapsular nerve group block; Drug: Morphine Sulfate Sponsor: Suez Canal University Enrolling by invitation Thu, 26 Aug 2021 12:00:00 EDT Morphine, Dyspnea, Exercise and COPDCondition: Chronic Obstructive Pulmonary DiseaseInterventions: Drug: Morphine; Drug: Placebo Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre Unknown status Wed, 31 Oct 2012 12:00:00 EDT The Effect of Pain Medication in Children With Acute Abdominal Pain and Its Implication Over the Surgeon's DecisionCondition: Abdominal PainIntervention: Drug: Morphine Sulfate Sponsor: University of Texas Southwestern Medical Center Withdrawn Tue, 10 Feb 2009 12:00:00 EST Study of Embeda (Kadian NT, ALO-01) in Subjects With Chronic Moderate to Severe Nonmalignant PainCondition: PainIntervention: Drug: ALO-01 (Morphine Sulfate Plus Naltrexone Hydrochloride ER) Sponsor: Pfizer Completed Mon, 25 Dec 2006 12:00:00 EST Analgesics in the Pre-hospital Setting: Implications on Hemorrhage Tolerance - MorphineCondition: HealthyInterventions: Drug: Morphine; Other: Placebo Sponsor: University of Texas Southwestern Medical Center Recruiting Thu, 24 Oct 2019 12:00:00 EDT
Patient Re-education vs. Background Morphine to IV-PCA in Patient With Unsatisfactory Analgesia Post LaparotomyCondition: Post-operative PainInterventions: Drug: morphine; Behavioral: Patient re-education Sponsor: Clinical Research Centre, Malaysia Unknown status Fri, 14 Aug 2015 12:00:00 EDT Low Dose Ketamine Versus Morphine for Moderate to Severe Pain in the Emergency DepartmentCondition: PainInterventions: Drug: Morphine; Drug: Ketamine Sponsor: Antonios Likourezos Completed Thu, 18 Apr 2013 12:00:00 EDT Pharmacokinetics of Morphine and Oxycodone in Frail Elderly Undergoing Cardiac SurgeryConditions: Opioid Use; Side Effect of Drug; Postoperative PainIntervention: Drug: Morphine & Oxycodone Sponsors: St. Antonius Hospital; Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) Recruiting Wed, 06 Jan 2021 12:00:00 EST Oral Pregabalin Effect to the Intravenous Morphine in Multiple Fracture RibsCondition: Fracture; Rib, MultipleInterventions: Drug: Pregabalin 150mg; Drug: Morphine Sponsor: Assiut University Unknown status Thu, 22 Mar 2018 12:00:00 EDT Intrathecal Hydromorphone for Pain Control After Cesarean SectionConditions: Pain; Cesarean SectionInterventions: Drug: Intrathecal morphine; Drug: Intrathecal hydromorphone Sponsor: Icahn School of Medicine at Mount Sinai Completed Wed, 26 Mar 2014 12:00:00 EDT Influence of Naloxone on Ticagrelor Pharmacokinetics and Pharmacodynamics in Patients With Unstable Angina Pectoris on Concomitant Treatment With MorphineCondition: Unstable Angina PectorisInterventions: Drug: Crushed ticagrelor followed by morphine; Drug: Crushed ticagrelor, morphine,naloxone Sponsor: Collegium Medicum w Bydgoszczy Completed Wed, 19 Oct 2016 12:00:00 EDT Influence of Metoclopramide on Ticagrelor Pharmacokinetics and Pharmacodynamics in Patients With Unstable Angina Pectoris on Concomitant Treatment With MorphineCondition: Unstable Angina PectorisInterventions: Drug: Crushed ticagrelor followed by morphine; Drug: Crushed ticagrelor, morphine,metoclopramide Sponsor: Collegium Medicum w Bydgoszczy Completed Wed, 19 Oct 2016 12:00:00 EDT MST for Parkinson's DiseaseConditions: Parkinson Disease; Depression; Movement Disorders; Major Depressive DisorderIntervention: Device: Magnetic Seizure Theapy (MagPro XP MST) Sponsor: University of British Columbia Recruiting Fri, 05 Mar 2021 12:00:00 EST Effect of Granisetron on Morphine Induced Pruritus in Cesarean SectionCondition: PruritusInterventions: Drug: Morphine Sulfate; Drug: Placebo; Drug: Granisetron Sponsor: Assiut University Completed Fri, 30 Mar 2018 12:00:00 EDT Effect of Intrathecal Morphine on Chronic Pain After Elective Caesarean SectionCondition: Chronic Pain Post-ProceduralInterventions: Drug: Morphine; Drug: Placebo Sponsor: B.P. Koirala Institute of Health Sciences Completed Fri, 02 Mar 2018 12:00:00 EST
Comparison of MEOPA + Paracetamol Versus Morphine Treatment in Acute Coronary Syndrome Analgesia.Condition: Acute Coronary SyndromeInterventions: Drug: MEOPA and paracetamol; Drug: Morphine Sponsor: University Hospital, Toulouse Completed Wed, 23 Jul 2014 12:00:00 EDT CORAL - Cebranopadol Versus Morphine Prolonged-release in Patients With Chronic Moderate to Severe Pain Related to CancerConditions: Pain; Neoplasms; Chronic PainInterventions: Drug: Cebranopadol; Drug: Morphine Prolonged Release Sponsor: Tris Pharma, Inc. Terminated Thu, 17 Oct 2013 12:00:00 EDT Combined Intrathecal Morphine and Dexmedetomidine AnalgesiaCondition: Postoperative PainInterventions: Drug: Dexmedetomidine (Precedex); Drug: Bupivacaine; Drug: Morphine Sponsor: Assiut University Completed Wed, 06 May 2015 12:00:00 EDT A Study to Compare Safety and Efficacy of Osmotic Release Oral Syytem (OROS) Hydromorphone Hydrochloride (HCl) With Morphine Sustain Release (SR) in Participants With Cancer PainCondition: Cancer PainInterventions: Drug: Hydromprphone Hydrochloride (HCl) OROS; Drug: Morphine Sustain Release (SR) Sponsor: Johnson & Johnson Taiwan Ltd Terminated Fri, 05 Dec 2008 12:00:00 EST Intrathecal Morphine Compared to Conventional Medical Management for Pain Control and Opioid-related Side EffectsCondition: Chronic PainInterventions: Device: SynchroMed Infusion System and Intrathecal Morphine Sulfate; Other: Conventional Medicine Sponsor: MedtronicNeuro Terminated Fri, 16 Aug 2013 12:00:00 EDT Visceral Pain From the Upper Urinary Tract - a Trial on the Effect of Morphine and Oxycodone in Patients Undergoing PCNLCondition: Kidney StonesInterventions: Drug: oxycodone; Drug: morphine Sponsors: Katja venborg Pedersen; Aalborg University Hospital Completed Tue, 04 Nov 2008 12:00:00 EST Morphine to Maximize the Benefits of Exercise Training in COPD or ILD and Persistent BreathlessnessConditions: Chronic Obstructive Pulmonary Disease; Interstitial Lung DiseaseInterventions: Drug: Exercise training with morphine; Other: Exercise training with placebo Sponsor: Dennis Jensen, Ph.D. Unknown status Thu, 31 Jan 2019 12:00:00 EST Intra-Articular Morphine Versus Bupivacaine on Knee Motion in Patients With OsteoarthritisCondition: AnalgesiaIntervention: Drug: morphine Sponsor: Federal University of São Paulo Completed Fri, 14 Mar 2008 12:00:00 EDT Orthostatic Intolerance and Hypotension After Administration of Morphine in Patients Prior to Hip or Knee ArthroplastyConditions: Orthostatic Hypotension; Orthostatic IntoleranceIntervention: Drug: Morphine Sponsors: Copenhagen University Hospital, Hvidovre; Henrik Kehlet Recruiting Wed, 26 May 2021 12:00:00 EDT Sustained-release Morphine Pharmacokinetics in Roux-en-Y Gastric Bypass SubjectsCondition: Bypass ComplicationsIntervention: Drug: Sustained release morphine sulfate, 30 mg Sponsor: Hopital Lariboisière Unknown status Tue, 29 Dec 2015 12:00:00 EST
Postoperative Pain Relief Following Total Hip Arthroplasty. A Comparison Between Intrathecal Morphine (IM) and Local Infiltration Analgesia (LIA)Condition: Primary Osteoarthritis Requiring Total Hip ReplacementInterventions: Drug: LIA; Drug: I/T morphine Sponsor: Region Örebro County Unknown status Mon, 24 Jan 2011 12:00:00 EST Low Pain Prediction in Cesarean Section PatientsConditions: Scheduled Cesarean Sections; Postoperative Pain Management; Side EffectsInterventions: Drug: duramorph; Drug: placebo Sponsor: Wake Forest University Health Sciences Terminated Tue, 20 May 2014 12:00:00 EDT Acupuncture Versus Titrated Morphine in Patients With Renal ColicCondition: Renal ColicInterventions: Procedure: Traditional Acupuncture Session; Drug: Morphine Titration Sponsor: University of Monastir Completed Tue, 24 May 2016 12:00:00 EDT Safety and Efficacy of Intrathecal Morphine in ChildrenCondition: Abdominal CancerIntervention: Procedure: intrathecal morphine Sponsor: Alaa Ali Mohamed Elzohry Completed Wed, 19 Apr 2017 12:00:00 EDT Self Medication With Oral Morphine After Total Knee Arthroplasty.Conditions: Arthroplasty, Knee Replacement; Pain ControlInterventions: Behavioral: Nurse dispensed oral morphine.; Behavioral: Patient self medication of oral morphine. Sponsors: The Royal Bournemouth Hospital; Royal Bournemouth and Christchurch Hospitals NHS Foundation Trust Completed Fri, 22 Oct 2010 12:00:00 EDT ANalgesic Efficacy and Safety of MOrphiNe Versus Methoxyflurane in Patients With Acute Myocardial InfarctionConditions: ST Elevation Myocardial Infarction; Non ST Segment Elevation Acute Coronary SyndromeInterventions: Drug: Methoxyflurane - Penthrox; Drug: Morphine Sponsor: Collegium Medicum w Bydgoszczy Recruiting Fri, 17 Jul 2020 12:00:00 EDT Ultrasound Guided ESP Block Versus Intrathecal Morphine for Postoperative Analgesia in Major HPB Surgery.Condition: Postoperative PainInterventions: Procedure: Erector Spinae Plane Block; Procedure: Intrathecal morphine Sponsor: Assiut University Not yet recruiting Thu, 19 Nov 2020 12:00:00 EST Efficacy of Paracetamol in Addition to Morphine to Improve Analgesia in the Emergency DepartmentCondition: AnalgesiaInterventions: Drug: Paracetamol; Drug: Placebo; Drug: Morphine Sponsor: Bruno Minotti Completed Mon, 18 Feb 2019 12:00:00 EST Analgesia Comparison of Nalbuphine and Morphine for Laparoscopic MyomectomyCondition: Postoperative PainInterventions: Drug: Nalbuphine; Drug: Morphine Sponsor: Peking University First Hospital Unknown status Wed, 20 Sep 2017 12:00:00 EDT Comparison of Side Effects of Morphine and Hydromorphone Patient-Controlled Analgesia (PCA)Condition: Post Operative PainInterventions: Drug: Morphine PCA; Drug: Hydromorphone PCA Sponsor: Columbia University Completed Mon, 09 Oct 2006 12:00:00 EDT
Intrathecal Morphine for Unilateral Total Knee ArthroplastyCondition: Primary Osteoarthritis of Knee NosInterventions: Procedure: 50 ug IT morphine; Procedure: 100 ug IT morphine; Procedure: No IT morphine; Drug: Morphine; Drug: Bupivacaine Sponsor: Mahidol University Completed Fri, 28 Jul 2017 12:00:00 EDT Comparison Between Methadone and Morphine for Neonatal Opiate WithdrawalCondition: Neonatal Abstinence SyndromeInterventions: Drug: Methadone; Drug: Morphine Sponsor: Eastern Maine Medical Center Completed Tue, 05 Mar 2013 12:00:00 EST A Efficacy and Safety Trial of Controlled Release (CR) Morphine in Cancer PatientsConditions: Pain; CancerIntervention: Drug: Morphine Sulphate Sponsor: Egalet Ltd Completed Mon, 12 Mar 2007 12:00:00 EDT Comparison of Intrathecal and Intravenous Analgesia in Patients Undergoing Liver ResectionConditions: Liver Diseases; Liver Cancer; Liver MetastasesInterventions: Procedure: Intravenous morphine; Procedure: Intrathecal morphine Sponsor: Medical University of Warsaw Unknown status Wed, 08 Aug 2018 12:00:00 EDT Intrathecal Morphine for Postoperative Analgesia Following Laparoscopic Bariatric SurgeryCondition: Postoperative PainInterventions: Drug: intrathecal morphine; Drug: intrathecal saline Sponsor: Assiut University Unknown status Thu, 07 Apr 2016 12:00:00 EDT Morphine as First Drug for Cancer PainCondition: Chronic PainIntervention: Drug: Opioid Sponsor: Federal University of São Paulo Completed Wed, 29 Feb 2012 12:00:00 EST Intravenous Buprenorphine Versus Morphine for Severe Pain in the Emergency DepartmentCondition: PainInterventions: Drug: Buprenorphine; Drug: Morphine Sulfate Sponsor: Alameda Health System Unknown status Tue, 22 Aug 2017 12:00:00 EDT Influence of Morphine on Pharmacokinetics and Pharmacodynamics of Ticagrelor in Patients With Acute Myocardial InfarctionConditions: ST-segment Elevation Myocardial Infarction; Non-ST-segment Elevation Myocardial Infarction; VA Drug InteractionsInterventions: Drug: Morphine; Drug: Placebo; Drug: Ticagrelor Sponsor: Collegium Medicum w Bydgoszczy Completed Fri, 15 Aug 2014 12:00:00 EDT Incidence of Headache Following an Unintentional Dural PunctureConditions: Postdural Puncture Headache; Post-Lumbar Puncture Headache; Cerebrospinal Fluid LeaksInterventions: Drug: Morphine; Drug: Saline Sponsor: Northwestern University Completed Thu, 07 Nov 2013 12:00:00 EST Effect of Combined Morphine and Duloxetine on Chronic PainConditions: Chronic Low Back Pain; Chronic Neck PainInterventions: Drug: Morphine; Drug: Duloxetine; Drug: Placebo Sponsor: Massachusetts General Hospital Recruiting Tue, 15 Aug 2017 12:00:00 EDT
The Optimal Dosage of Intrathecal Morphine for Peripartum AnalgesiaCondition: Labor PainInterventions: Drug: Morphine; Drug: Saline Sponsor: Beth Israel Deaconess Medical Center Terminated Thu, 17 Jun 2010 12:00:00 EDT Efficacy of Dexmedetomidine Versus Morphine as an Adjunct to Bupivacaine in Caudal Anesthesia.Condition: Anesthesia, LocalInterventions: Drug: Dexmedetomidine; Drug: Morphine Sponsor: Cairo University Completed Wed, 24 Jun 2020 12:00:00 EDT Acupuncture Versus IV Morphine in the Treatment of Acute Pain in EDCondition: Renal ColicInterventions: Device: acupuncture; Drug: Morphine Sponsors: University of Monastir; Emergency NGO Onlus Completed Mon, 02 Jun 2014 12:00:00 EDT An Efficacy and Safety Study to Compare Morphine 6-glucuronide (M6G) and Morphine in Patients Suffering With Post-Operative Pain for at Least 24 HoursCondition: Postoperative PainInterventions: Drug: Morphine 6-glucuronide; Drug: Morphine Sponsors: Paion UK Ltd.; Chiltern International Ltd.; HFL Ltd. Completed Mon, 08 Mar 2010 12:00:00 EST a Small Dose of Naloxone,Minimize Intrathecal Morphine Side EffectsCondition: Post-Op ComplicationInterventions: Drug: Morphine; Drug: Morphine-Naloxone Sponsor: Assiut University Completed Wed, 26 Jul 2017 12:00:00 EDT Comparison of Surgical Rectus Sheath Block and Intrathecal MorphineCondition: PainInterventions: Drug: Bupivacaine; Drug: Morphine Sponsor: Queen Mary Hospital, Hong Kong Completed Fri, 03 Jun 2016 12:00:00 EDT Single Dose Morphine and Fentanyl Added to Intrathecal Mixture on Orthopedics Patients With Undiagnosed Obstructive Sleep ApneaCondition: Obstructive Sleep Apnea of AdultInterventions: Drug: Morphine; Drug: Fentanyl Sponsor: University of Malaya Unknown status Wed, 18 Dec 2013 12:00:00 EST Pharmacokinetic, Pharmacodynamic and Pharmacogenetic of Morphine After SurgeryCondition: Orthopaedic SurgeryIntervention: Drug: intravenous morphine titration Sponsor: Assistance Publique - Hôpitaux de Paris Completed Wed, 14 Jan 2009 12:00:00 EST Conversion to Embeda With Rescue TrialConditions: Chronic Disease; PainIntervention: Drug: morphine sulfate and naltrexone hydrochloride (EMBEDA) Sponsor: Pfizer Terminated Wed, 11 Aug 2010 12:00:00 EDT Continuous Pre-uterine Wound Infiltration Versus Intrathecal Morphine for Postoperative Analgesia After Cesarean SectionCondition: Postoperative PainInterventions: Drug: Ropivacaine; Drug: Morphine Sponsors: Central Hospital, Nancy, France; Maternite Regionale Universitaire Unknown status Fri, 31 Oct 2014 12:00:00 EDT
Morphine Added to Ropivacaine for FICB for Postoperative AnalgesiaCondition: Postoperative PainInterventions: Drug: Ropivacaine, Morphine; Drug: Ropivacaine, Saline Sponsor: B.P. Koirala Institute of Health Sciences Completed Thu, 14 Mar 2019 12:00:00 EDT IV Acetaminophen vs IV Morphine for Pain Control in Pregnant WomenCondition: Pain Management in Pregnant WomenInterventions: Drug: IV Acetaminophen; Drug: IV Morphine Sponsor: The University of Texas Health Science Center, Houston Terminated Fri, 17 Oct 2014 12:00:00 EDT Ultrasound Guided TAP Block for Postoperative Analgesia After Abdominal Surgery.Condition: Postoperative PainInterventions: Drug: Bupivacaine 0.25% 20ml on each side Sonar guided TAB; Drug: Morphine 10mg; Drug: Morphine 15mg Sponsor: Assiut University Completed Tue, 29 Nov 2016 12:00:00 EST MIdazolam Versus MOrphine in Acute Pulmonary Edema (MIMO Trial)Condition: Acute Pulmonary EdemaInterventions: Drug: Midazolam; Drug: Morphine Sponsor: Alberto Dominguez-Rodriguez Unknown status Fri, 05 Aug 2016 12:00:00 EDT Spinal Hydromorphone Versus Morphine for Post-Cesarean Delivery AnalgesiaCondition: Postoperative PainInterventions: Drug: Spinal Hydromorphone; Drug: Spinal Morphine Sponsor: Lawson Health Research Institute Recruiting Thu, 19 Jul 2018 12:00:00 EDT Safety and Efficacy Study of Hydromorphone and MorphineCondition: PainInterventions: Drug: Morphine; Drug: Hydromorphone Sponsor: Montefiore Medical Center Completed Tue, 20 Sep 2005 12:00:00 EDT Post-operative Oral Morphine Versus IbuprofenCondition: Post-operative PainInterventions: Drug: oral morphine; Drug: Ibuprofen Sponsor: Lawson Health Research Institute Completed Tue, 18 Sep 2012 12:00:00 EDT Comparison Between Dexamethasone and Morphine as an Adjuvant to Bupivacaine for Post-operative AnalgesiaCondition: Lower Extremities FractureInterventions: Drug: Dexamethasone 8 mg; Drug: Morphine 2 mg Sponsor: Indonesia University Completed Mon, 13 Feb 2017 12:00:00 EST Intrathecal Morphine on Transcranial Electric Motor-Evoked PotentialsCondition: Trauma, Nervous SystemIntervention: Drug: Intrathecal Morphine Sponsor: Children's Hospital of Philadelphia Completed Thu, 17 Jan 2008 12:00:00 EST A Study to Assess the Safety, Tolerability and Pharmacokinetics of Multiple Doses of ASP8062 With a Single Dose of Morphine in Recreational Opioid Using ParticipantsCondition: Opioid Use DisorderInterventions: Drug: ASP8082; Drug: morphine; Drug: Placebo Sponsors: Astellas Pharma Global Development, Inc.; National Institute on Drug Abuse (NIDA) Completed Fri, 26 Jun 2020 12:00:00 EDT
TC02 Obese Women Using It Morphine vs PCA IV Hydromorphone for Post-Cesarean AnalgesiaConditions: Pain, Postoperative; Obesity; Respiratory InsufficiencyInterventions: Drug: Intrathecal Morphine; Drug: Intravenous hydromorphone Sponsor: Northwestern University Withdrawn Thu, 14 Sep 2017 12:00:00 EDT Efficacy of Morphine in Reducing the Rate of Early Non-Invasive Ventilation Failure in Acute Exacerbation of Chronic Obstructive Pulmonary Disease, Phase I/IIaCondition: Chronic Obstructive Pulmonary DiseaseIntervention: Drug: Morphine hydrochloride Sponsor: University Hospital, Grenoble Recruiting Thu, 11 Jun 2020 12:00:00 EDT Respiratory Depression in Women With BMI≥30 Underwent Spinal Anesthesia With Intrathecal Morphine in Elective C-sectionCondition: Respiratory DepressionInterventions: Device: SOMNOTOUCH RESP; Procedure: Caesarean section; Drug: Spinal anesthesia with intrathecal morphine Sponsor: Rambam Health Care Campus Unknown status Thu, 30 Jun 2016 12:00:00 EDT Problems With Morphine Use in Patients With a Severe Brain InjuryConditions: Head Trauma; Subarachnoid Hemorrhage; Close Head InjuryIntervention: Drug: morphine Sponsors: Dalhousie University; Canadian Institutes of Health Research (CIHR) Unknown status Tue, 20 Sep 2005 12:00:00 EDT The Clinical Evaluation of Implantable Pump System For Safety And Delivery Accuracy In Patients Requiring Intrathecal Administration Of Morphine Sulfate For Chronic PainConditions: Cancers; Chronic PainIntervention: Device: Implantation of Morphine Sulfate delivering programmable pump Sponsor: Medallion Therapeutics, Inc. Completed Fri, 20 Aug 2010 12:00:00 EDT Epidural Morphine for Postoperative Analgesia After Total Knee ArthroplastyConditions: Adult Patients; Total Knee Arthroplasty; Epidural Analgesia; Femoral Nerve Block; Analgesic Adverse ReactionInterventions: Procedure: Epidural morphine; Procedure: Epidural placebo; Procedure: Single femoral nerve block; Drug: Intravenous morphine analgesia Sponsor: Peking University First Hospital Completed Thu, 29 Jun 2017 12:00:00 EDT Transversus Abdominis Plane Block Versus Spinal Morphine After Caesarean Section : A Comparison StudyCondition: Pregnancy, Ceasarian Section, AnaesthesiaIntervention: Drug: Intrathecal morphine Sponsor: Mbarara University of Science and Technology Completed Mon, 28 Aug 2017 12:00:00 EDT Study to Determine the Bioavailability, Pharmacodynamic Effects, and Safety of Whole and Crushed ALO-01 Compared to Morphine Sulfate Immediate Release (MSIR)Condition: HealthyInterventions: Drug: ALO-01; Drug: MSIR; Drug: Placebo Sponsor: Pfizer Completed Fri, 12 Sep 2008 12:00:00 EDT Integrated Pulmonary Index and Opioid Based Patient Controlled AnalgesiaCondition: Brain TumorsInterventions: Drug: Morphine PCA 1 mg; Drug: Morphine PCA 0,5 mg; Drug: Placebo Sponsor: Istanbul University Completed Wed, 18 Mar 2020 12:00:00 EDT Baseline Epidemiologic Assessment of Abuse-Deterrence of MorphaBond Extended Release (BEAD-MB)Condition: Baseline Epidemiologic AssessmentInterventions: Drug: MorphaBond ER; Drug: Comparator Drug Sponsor: Daiichi Sankyo, Inc. Completed Thu, 25 Jul 2019 12:00:00 EDT
Oral Morphine Versus IbuprofenConditions: Upper Extremity Fractures; Analgesia Post FractureInterventions: Drug: Oral morphine; Drug: Ibuprofen Sponsor: Naveen Poonai Completed Mon, 24 Sep 2012 12:00:00 EDT Post-cesarean Analgesia With Epidural Morphine Following Epidural 2-chloroprocaineConditions: Physiological Effect of Drugs; Morphine; Analgesics; Analgesics, Opioid; Central Nervous System Depressants; NarcoticsInterventions: Drug: 2% lidocaine with 1:200,000 epinephrine and epidural morphine; Drug: 3% 2-chloroprocaine and epidural morphine Sponsor: The University of Texas Health Science Center, Houston Completed Thu, 30 Apr 2020 12:00:00 EDT The Use of Intrathecal Morphine in the Management of Acute Pain Following Decompressive Lumbar Spinal SurgeryCondition: Acute Pain Following Decompressive Lumbar Spinal SurgeryInterventions: Drug: Intrathecal Morphine; Drug: Intrathecal Saline Sponsor: University of Calgary Completed Thu, 21 Jan 2010 12:00:00 EST Efficacy of Fentanyl to Reduce the Time of Severe Postoperative Pain Relief Compared to MorphineCondition: Postoperative PainInterventions: Drug: Fentanyl; Drug: Morphine Sponsor: Universidad de Antioquia Completed Fri, 23 May 2014 12:00:00 EDT Efficacy and Safety Study of Gabapentin as add-on to Morphine in Paediatric Patients Affected by Chronic PainCondition: Chronic PainInterventions: Drug: Gabapentin + Morphine; Drug: Placebo + Morphine Sponsors: Pharmaceutical Research Management srl; European Commission Withdrawn Thu, 07 Sep 2017 12:00:00 EDT Palliation of Dyspnea With Morphine in Patients With Interstitial Lung DiseaseConditions: Interstitial Lung Disease; Dyspnea; MorphineInterventions: Drug: Morphine hydrochloride; Other: Placebo Sponsors: University of Aarhus; Skanderbog Apotek Completed Fri, 04 Dec 2015 12:00:00 EST Morphine Sulfate/Placebo for the Treatment of PulmonAry Fibrosis CoughCondition: Idiopathic Pulmonary FibrosisInterventions: Drug: Morphine Sulfate; Drug: Placebo oral tablet Sponsor: Royal Brompton & Harefield NHS Foundation Trust Recruiting Fri, 12 Jun 2020 12:00:00 EDT Intrathecal Morphine and Fentanyl for Knee ArthroplastyCondition: Knee ArthroplastyInterventions: Drug: Intrathecal morphine; Drug: Intrathecal fentanyl Sponsor: Keimyung University Dongsan Medical Center Unknown status Thu, 07 Dec 2017 12:00:00 EST Prevention of Hyperalgesia With Epidural MorphineCondition: HyperalgesiaInterventions: Drug: Morphine; Drug: Serum physiologic Sponsor: Cukurova University Unknown status Fri, 21 Jul 2017 12:00:00 EDT Pharmacokinetics of Oral Morphine and Pharmacogenomics of CYP2D6 and UGT2B7, in an Urban Pediatric Population Presenting for Elective SurgeryCondition: PainIntervention: Drug: Morphine Sponsor: University of British Columbia Completed Fri, 19 Feb 2010 12:00:00 EST
Intrathecal Morphine in Robot-assisted ProstatectomyCondition: Prostatic NeoplasmsInterventions: Drug: The intravenous patient-controlled analgesia; Drug: The intrathecal morphine injection Sponsor: Seoul National University Hospital Completed Mon, 25 Nov 2013 12:00:00 EST Blinded Trial of Buprenorphine or Morphine in the Treatment of the Neonatal Abstinence SyndromeCondition: Neonatal Abstinence SyndromeInterventions: Drug: sublingual buprenorphine; Drug: oral morphine Sponsors: Thomas Jefferson University; National Institute on Drug Abuse (NIDA) Completed Mon, 17 Oct 2011 12:00:00 EDT Effects of a Surgery-induced Peripheral Inflammatory Response on the Blood Brain BarrierCondition: Dissecting Aneurysm of the Thoracic AortaIntervention: Drug: morphine Sponsors: Nova Scotia Health Authority; Dalhousie University Completed Wed, 08 Apr 2009 12:00:00 EDT Thoracic Epidural Analgesia in Flail ChestCondition: Flail ChestInterventions: Drug: Morphine Sulfate; Drug: Triamcinolone Acetonide Sponsor: Assiut University Unknown status Mon, 29 Jan 2018 12:00:00 EST Intra-articular Morphine and Clonidine Injections for Pain Management in Hip ArthroscopyConditions: Femoracetabular Impingement; Pain, PostoperativeInterventions: Drug: Morphine with clonidine; Other: Normal saline Sponsor: Northwestern University Completed Thu, 20 Aug 2015 12:00:00 EDT Neuraxial Preservative Free Morphine for Normal Spontaneous Vaginal DeliveryConditions: Postpartum Pain; Postpartum Depression; Opioid ConsumptionInterventions: Drug: Preservative Free Morphine; Drug: Saline Sponsor: Icahn School of Medicine at Mount Sinai Recruiting Fri, 12 Jul 2019 12:00:00 EDT Postoperative Hemodynamics Comparison After High Spinal Block With or Without Intrathecal Morphine.Condition: VasoplegiaInterventions: Drug: Bupivacaine; Drug: Bupivacaine + Morphine Sponsor: Postgraduate Institute of Medical Education and Research Unknown status Thu, 07 Jul 2016 12:00:00 EDT Comparison of the Erector Spinae Plane Block Versus Intrathecal Morphine on Post-Cesarean Delivery AnalgesiaCondition: Cesarean Section ComplicationsInterventions: Procedure: Erector Spinae Plane Block; Drug: Intrathecal morphine Sponsors: McGill University Health Centre/Research Institute of the McGill University Health Centre; Thammasat University Recruiting Wed, 05 Feb 2020 12:00:00 EST Morphine for Treatment of Dyspnea in Patients With COPDCondition: Pulmonary Disease, Chronic ObstructiveInterventions: Drug: sustained release morphine; Drug: placebo Sponsors: Maastricht University Medical Center; ZonMw: The Netherlands Organisation for Health Research and Development Completed Wed, 29 Apr 2015 12:00:00 EDT An Efficacy and Safety Study to Compare Fentanyl Ionsys and Routine Care With Intravenous (IV) Morphine Patient-controlled Analgesia (PCA) in Participants Who Have Undergone Elective Major Abdominal or Orthopedic SurgeryCondition: Pain, PostoperativeInterventions: Device: Fentanyl IONSYS; Device: Morphine IV PCA Sponsor: Janssen-Cilag Ltd. Terminated Mon, 06 Oct 2008 12:00:00 EDT
intrathecaم Ketamine, Morphine and Both for Lower Abdominal Cancer Surgery PainCondition: Postoperative PainInterventions: Drug: intrathecal morphine; Drug: intrathecal ketamine; Drug: intrathecal morphine + ketamine Sponsor: Assiut University Completed Mon, 04 Apr 2016 12:00:00 EDT Effect of Intrathecal Morphine, Dexmedetomidine or Both in Combination to Bupivacaine on ImmunityCondition: Immune System SuppressionInterventions: Drug: Morphine Sulfate; Drug: Dexmedetomidine; Drug: Bupivacaine Sponsor: Assiut University Active, not recruiting Thu, 19 Jan 2017 12:00:00 EST A Randomized Controlled Trial Comparing Intrathecal Morphine With Quadratus Lumborum Block for Post-cesarean Delivery AnalgesiaCondition: Cesarean SectionInterventions: Other: Bilateral Quadratus lumborum block with 0.5% ropivacaine; Other: Intrathecal Morphine with 100 mcg morphine Sponsors: Vishal Uppal; IWK Health Centre; Maisonneuve-Rosemont Hospital Recruiting Thu, 18 Aug 2016 12:00:00 EDT RANDOMISED STUDY OF EPIDURAL VS MPCA MORPHINE VS TAPP IN LAPAROSCOPIC SIGMOIDECTOMYCondition: Sigmoidal TumourInterventions: Drug: L-BUPIVACAINE ; MORPHINE; Drug: MORPHINE Sponsor: Corporacion Parc Tauli Unknown status Mon, 08 Apr 2013 12:00:00 EDT Ketamine and Morphine Versus Morphine Alone for the Treatment of Acute Pain in the Emergency DepartmentCondition: Acute PainInterventions: Drug: Ketamine; Drug: Morphine; Drug: placebo Sponsors: University of Arizona; Arizona College of Emergency Physicians Unknown status Wed, 17 Jul 2013 12:00:00 EDT Morphine vs. Oxycodone for Postoperative Pain ManagementConditions: Hysterectomy; Myoma; Postoperative Pain; OpioidsIntervention: Drug: Morphine and oxycodone Sponsors: Ullevaal University Hospital; University of Oslo Completed Wed, 12 Sep 2007 12:00:00 EDT Dosage of Epidural Morphine in Elderly PatientsConditions: Age Problem; Abdominal CancerInterventions: Drug: 1.5 mg of Morphine Sulfate; Drug: Normal saline; Drug: 3 mg of Morphine Sulfate; Drug: 4.5 mg of Morphine Sulfate Sponsor: Assiut University Completed Fri, 20 Mar 2020 12:00:00 EDT Analgesic Efficacy of Paravertebral MorphineCondition: Acute PainInterventions: Drug: PVB morphine; Drug: PVB bupivacaine Sponsor: Assiut University Unknown status Wed, 20 Dec 2017 12:00:00 EST OxyNorm Capsules in Post-Operative Pain StudyCondition: Postoperative PainInterventions: Drug: OxyNorm Capsules; Other: Morphine tablet Sponsor: Mundipharma (China) Pharmaceutical Co. Ltd Completed Thu, 30 Aug 2012 12:00:00 EDT Measuring the Amount of Methadone or Morphine in the Blood of Neonates, Infants & Children After Cardiac Surgery.Condition: PainInterventions: Drug: Methadone; Drug: Morphine Sponsors: Stanford University; University of Colorado, Denver; Oregon Health and Science University Completed Mon, 29 Mar 2010 12:00:00 EDT
Low Dose Morphine to Relieve Dyspnea in Acute Respiratory Failure (OPIDYS)Condition: Acute Respiratory FailureInterventions: Drug: Chlorhydrate de morphine; Drug: NaCl 0,9%, Sponsor: Assistance Publique - Hôpitaux de Paris Recruiting Fri, 24 Apr 2020 12:00:00 EDT Postoperative Effects of Intranasal Fentanyl, IV and IM Morphine in Children Undergoing MyringotomyCondition: Otitis MediaInterventions: Drug: Intranasal fentanyl; Drug: morphine IM; Drug: IV morphine Sponsor: Baylor College of Medicine Completed Fri, 19 Nov 2010 12:00:00 EST Comparing Clinical Outcomes Between Ketamine-midazolam and Morphine-midazolam for Continous Sedation in ICU Patients.Condition: Critical IllnessInterventions: Combination Product: Ketamine-Midazolam; Combination Product: Morphine -Midazolam Sponsors: Makerere University; THRiVE Terminated Tue, 23 Jan 2018 12:00:00 EST Erector Spinae Block vs Morphine in Vertebral FixationConditions: Vertebral Subluxation; Spine Disease; SpondylolisthesisInterventions: Procedure: Erector Spinae plane Block; Drug: Patient controlled analgesia with intravenous morphine Sponsor: AUSL Romagna Rimini Recruiting Thu, 28 Jan 2021 12:00:00 EST Intrathecal Morphine,Femoral Nerve Block,Periarticular Bupivacaine Infiltration for Pain After Intramedullary Hip ScrewCondition: Femoral Neck FracturesIntervention: Drug: Bupivacaine, morphine Sponsor: Mahidol University Unknown status Wed, 13 Oct 2010 12:00:00 EDT Morphine Versus Methadone As First Line Strong Opioid for Cancer PainConditions: Advanced Cancer; Solid TumorsInterventions: Drug: Morphine; Drug: Methadone Sponsors: M.D. Anderson Cancer Center; National Cancer Institute (NCI) Terminated Wed, 12 Mar 2008 12:00:00 EDT Efficacy of Transverses Abdominis -Plane Block With Bupivacaine Versus Bupivacaine With Morphine PostoperativelyCondition: Abdominal CancerIntervention: Drug: transversus abdominis-plane block with local anesthetic 20 ml of bupivacaine 0.5% + 10 mg morphine Sponsor: Assiut University Completed Fri, 02 Oct 2015 12:00:00 EDT Optimizing the Use of Morphine in Pre-Term NeonatesCondition: Premature NeonatesIntervention: Drug: Morphine Sponsors: John van den Anker; University of Louisville; Erasmus Medical Center Completed Fri, 29 Jun 2007 12:00:00 EDT Morphine Versus Ketamine as Adjuvants in Paravertebral BlocksConditions: Pain, Postoperative; Pain, Acute; Pain, Chronic; Pain, Neuropathic; Morphine; Ketamine; AnalgesiaInterventions: Drug: local anesthetic-morphine; Drug: local anesthetic-ketamine; Drug: local anesthetic Sponsors: Aretaieion University Hospital; KAT General Hospital Active, not recruiting Wed, 21 Apr 2021 12:00:00 EDT Intrathecal Opioids for Pain Control After Cesarean Delivery: Determining the Optimal DoseConditions: Analgesia, Obstetrical; Cesarean SectionInterventions: Drug: Morphine; Drug: Hydromorphone Sponsor: Mayo Clinic Completed Thu, 12 Dec 2013 12:00:00 EST
Comparison of Transdermal Fentanyl and Morphine for Oral Mucositis Pain in Nasopharyngeal Cancer PatientsConditions: Pain; Nasopharyngeal Carcinoma; Head and Neck Cancer; Radiation Induced Oral MucositisInterventions: Drug: Fentanyl; Drug: Morphine Sponsor: Jiarong Chen, MD Not yet recruiting Tue, 03 Mar 2020 12:00:00 EST Safety Study to Assess Opiate Withdrawal Signs and Symptoms in Opioid Dependent PatientsCondition: Chronic PainInterventions: Drug: EMBEDA™ (morphine sulfate/naltrexone hydrochloride) crush; Drug: EMBEDA™ (morphine sulfate/naltrexone hydrochloride) whole Sponsor: Pfizer Terminated Fri, 09 Apr 2010 12:00:00 EDT Comparing Ketamine and Morphine in the Treatment of Acute Fracture PainConditions: Acute Pain; FracturesInterventions: Drug: ketamine; Drug: morphine Sponsors: Washington University School of Medicine; MOCEP Terminated Thu, 30 Apr 2015 12:00:00 EDT A Study of Embeda (Kadian NT, ALO-01) in Subjects With Pain Due to Osteoarthritis of the Hip or KneeConditions: Osteoarthritis; Chronic PainInterventions: Drug: ALO-01 (Morphine Sulfate Plus Naltrexone Hydrochloride Extended Release); Drug: Placebo Sponsor: Pfizer Completed Thu, 11 Jan 2007 12:00:00 EST Epidural Morphine for Analgesia After Traumatic Vaginal DeliveryCondition: Traumatic Vaginal DeliveryInterventions: Drug: Morphine; Drug: Placebo Sponsor: Lawson Health Research Institute Withdrawn Fri, 21 Sep 2012 12:00:00 EDT Nasal Fentanyl for Chronic Cancer PainConditions: Cancer; PainInterventions: Drug: intranasal fentanyl spray; Drug: slow release morphine Sponsors: Norwegian University of Science and Technology; St. Olavs Hospital; Fondazione IRCCS Istituto Nazionale dei Tumori, Milano; L'Hospitalet de Llobregat; University Hospital, Bonn; Cantonal Hospital of St. Gallen; Maastricht University Medical Center; Flinders University Withdrawn Tue, 23 Jul 2013 12:00:00 EDT Ropivacaine Through Continuous Infusion Versus Epidural Morphine for Postoperative Analgesia After Emergency Cesarean SectionCondition: Postoperative PainInterventions: Drug: Ropivacaine; Drug: Morphine Sponsor: University Hospital, Grenoble Active, not recruiting Tue, 07 Apr 2015 12:00:00 EDT Transversus Abdominis Plane (TAP) Block Versus Intrathecal Morphine for Caesarean Section - Randomised Controlled TrialCondition: Postoperative PainInterventions: Other: spinal anesthesia with intrathecal morphine; Other: TAP-block with ropivacaine and clonidine Sponsors: Benno Rehberg-Klug; Domitille Dereu Completed Thu, 29 Aug 2013 12:00:00 EDT Effect of Timing on Efficacy of Morphine Analgesia After 2-chloroprocaine AnesthesiaConditions: Labor; Analgesia, EpiduralInterventions: Drug: Morphine-CP-saline (MCS); Drug: saline-2CP-morphine (SCM); Drug: saline-lidocaine-morphine (SLM) Sponsor: Northwestern University Completed Fri, 15 Jun 2007 12:00:00 EDT Intrathecal Morphine for Inguinal Hernia Repair.Conditions: Inguinal Hernia; Nausea; Vomiting; Pruritus; Postoperative PainInterventions: Drug: intrathecal morphine 0.1 mg combined with intrathecal heavy bupivacaine 7.5 mg; Drug: intrathecal morphine 0.4 mg combined with intrathecal heavy bupivacaine 7.5 mg; Device: standard monitoring with Datex Ohmeda anesthesia monitor, GE, Finland; Drug: intravenous cannulation and premedication Sponsor: Ankara University Completed Thu, 05 Dec 2013 12:00:00 EST
Use of Morphine Gel Topically in Patients With Stage 2-3 WoundsCondition: WoundsInterventions: Drug: morphine topical gel; Drug: placebo Sponsor: Banner Health Unknown status Fri, 19 Sep 2008 12:00:00 EDT Epidural Methadone in Healthy VolunteersCondition: Pain, AcuteInterventions: Drug: Methadone hydrochloride; Drug: Morphine Sulfate Sponsor: simon.haroutounian Completed Tue, 15 May 2018 12:00:00 EDT Epidural Low Dose Morphine in Postoperative Pain After Posterior Lumbar Spinal SurgeryCondition: MorphineInterventions: Drug: 1 mg morphine soak in epidural oxidized cellulose; Drug: normal saline Sponsor: Mahidol University Completed Thu, 20 Feb 2014 12:00:00 EST Effects of Analgesics in Cesarean Section ElectiveCondition: Anesthesia; FunctionalInterventions: Drug: Hyperbaric bupivacaine+Sufentanil; Drug: Hyperbaric bupivacaine+Morphine Sponsor: Fundación Pública Andaluza Progreso y Salud Completed Fri, 29 Dec 2017 12:00:00 EST Intravenous Subdissociative-dose Ketamine Versus Morphine for Prehospital AnalgesiaCondition: Pain ManagementInterventions: Drug: Ketamine; Drug: Morphine Sponsor: Nantes University Hospital Recruiting Wed, 02 Aug 2017 12:00:00 EDT Fentanyl Buccal Tablet for the Relief of Episodic Breathlessness in Cancer PatientsConditions: Cancer; Dyspnea, ParoxysmalInterventions: Drug: Fentanyl; Drug: Immediate release morphine Sponsors: University of Cologne; Teva Pharmaceutical Industries Completed Thu, 19 Nov 2020 12:00:00 EST IV Paracetamol vs IV Morphine vs Placebo in SciatalgiaCondition: SciaticaInterventions: Drug: Paracetamol; Drug: morphine; Drug: Placebo Sponsors: Akdeniz University; Pamukkale University; Antalya Training and Research Hospital; University of Gaziantep; Ataturk University Unknown status Wed, 22 Jul 2015 12:00:00 EDT Trial Comparing Morphine to Hydromorphone in Elderly Patients With Severe PainCondition: Acute PainInterventions: Drug: Morphine; Drug: Hydromorphone Sponsor: Montefiore Medical Center Completed Tue, 21 Mar 2006 12:00:00 EST Intrathecal Morphine and Local Infiltration Analgesia in Total Knee ArthroplastyCondition: Pain, PostoperativeInterventions: Drug: Bupivacaine Hydrochloride, Spinal; Drug: Morphine hydrochloride, Spinal; Drug: Placebo - Concentrate Sponsor: South Carelia Central Hospital Unknown status Thu, 15 Feb 2018 12:00:00 EST The Effect of Morphine on Prasugrel Absorption in STEMI PatientsCondition: Cardiovascular DiseaseInterventions: Drug: morphine; Drug: saline Sponsor: Sheffield Teaching Hospitals NHS Foundation Trust Completed Wed, 22 Feb 2012 12:00:00 EST
Neuroimmune Effects of Opioid AdministrationCondition: Drug EffectInterventions: Drug: High Morphine Dose; Drug: Low Morphine Dose Sponsor: Yale University Completed Fri, 11 Jan 2019 12:00:00 EST Safety and Efficacy of the Addition of Morphine Chloride to a Low Dose of Bupivacaine as Intradural Anaesthetic for the Removal Surgery of the HemorrhoidsCondition: Surgical Remove of HemorrhoidsInterventions: Drug: Bupivacaine low dose; Drug: Bupivacaine standard dose; Drug: Morphine Chloride Sponsors: Fundacion para la Investigacion Biomedica del Hospital Universitario Principe de Asturias; Spanish Agency of Medicines and Health Products; Spanish Health Ministry Completed Tue, 28 Jan 2014 12:00:00 EST Use of Caudal Anesthesia Supplemented With Morphine in Children Undergoing Renal SurgeryCondition: Anesthesia, CaudalInterventions: Drug: caudal anesthesia; Drug: caudal anesthesia supplemented with morphine Sponsor: Shaare Zedek Medical Center Completed Wed, 05 Jun 2013 12:00:00 EDT Wound Infusion vs Spinal Morphine for Post-caesarean AnalgesiaCondition: Post Caesarean AnalgesiaInterventions: Drug: ropivacaine infiltration; Drug: intrathecal morphine; Drug: placebo Sponsor: Dr Madeleine Wilwerth Completed Wed, 15 Oct 2014 12:00:00 EDT Effetc of Intrathecal Morphine on Vesical Function After Caesarean SectionCondition: AnalgesiaInterventions: Drug: Morphine; Drug: NaCl 0.9%; Drug: 50 mg prilocaine + 2.5 mcg sufentanil Sponsor: University of Liege Not yet recruiting Mon, 13 Sep 2021 12:00:00 EDT Comparison of Adverse Drug Reactions Associated for Oxycodone and Morphine in Postoperative Pain After Abdominal HysterectomyCondition: Pain, PostoperativeInterventions: Drug: Morphine; Drug: Oxycodone Sponsor: Hospital Civil de Guadalajara Unknown status Tue, 18 Oct 2016 12:00:00 EDT First Evaluation of Morphine Hydrochloride by Nebulisation in Healthy VolunteersCondition: Acute PainInterventions: Drug: Morphine; Drug: Fentanyl Sponsor: University Hospital, Rouen Completed Tue, 05 Nov 2013 12:00:00 EST Comparison of KADIAN 100 mg When Dosed With Alcohol Under Fasting and Fed Conditions Compared to WaterCondition: HealthyInterventions: Drug: KADIAN Capsule + alcohol (under fasting conditions); Drug: KADIAN Capsule + water (under fasting conditions); Drug: morphine sulfate IR oral solution + water; Drug: KADIAN Capsule + alcohol (under fed conditions) Sponsor: Actavis Inc. Completed Tue, 07 Oct 2008 12:00:00 EDT Nalbuphine Versus Morphine for Mucositis Pain in Pediatric Cancer PatientsConditions: Acute Myeloid Leukemia; Stem Cell LeukemiaInterventions: Drug: Nalbuphine; Drug: Morphine Sponsor: Children's Cancer Hospital Egypt 57357 Completed Thu, 31 Jan 2019 12:00:00 EST Double Bedtime Dosing During Immediate-release Morphine Administration to Cancer PatientsCondition: CancerInterventions: Drug: single dose Morphine; Drug: double dose Morphine; Drug: placebo Sponsor: Norwegian University of Science and Technology Completed Tue, 20 Sep 2005 12:00:00 EDT
The Efficacy of Peripheral Nerve Blocks With Intrathecal Morphine in Improving Analgesia After Unilateral Total Knee ArthroplastyConditions: Anesthesia; Total Knee ArthroplastyInterventions: Drug: Combined spinal epidural anesthesia technique with intrathecal morphine; Drug: A combination of combined spinal-epidural (with intrathecal morphine) and femoral nerve block; Drug: A combination of combined spinal-epidural (with intrathecal morphine) and femoral nerve block as well as sciatic nerve block Sponsor: American University of Beirut Medical Center Completed Fri, 09 May 2014 12:00:00 EDT Magnetic Seizure Therapy (MST) for Treatment Resistant Depression, Schizophrenia, and Obsessive Compulsive DisorderConditions: Depressive Disorder; Schizophrenia; Schizoaffective Disorder; Obsessive-Compulsive DisorderIntervention: Device: Magnetic Seizure Therapy (MagPro MST) Sponsors: Centre for Addiction and Mental Health; University Health Network, Toronto Completed Fri, 11 May 2012 12:00:00 EDT Dexmedetomidine Versus Morphine and Midazolam in Prevention and Treatment of Delirium After Adult Cardiac SurgeryCondition: DeliriumInterventions: Drug: Dexmedetomidine Hydrochloride; Drug: Morphine and Midazolam Sponsor: Ain Shams University Completed Tue, 14 Mar 2017 12:00:00 EDT Dose Proportionality and Food Effect of Morphine SulfateCondition: PainIntervention: Drug: morphine sulfate Sponsor: Roxane Laboratories Completed Wed, 14 Oct 2009 12:00:00 EDT Low-dose Ketamine for Acute Pain in the Emergency DepartmentCondition: PainInterventions: Drug: Ketamine; Drug: Placebos; Drug: Morphine Sponsor: Faculty of Medicine, Sousse Unknown status Wed, 11 Jan 2017 12:00:00 EST Topical Morphine for Analgesia in Patients With Skin GraftsConditions: Skin Transplantation; PainInterventions: Other: Placebo; Drug: Morphine - .25 mg; Drug: Morphine Sponsor: Rambam Health Care Campus Not yet recruiting Wed, 09 Aug 2006 12:00:00 EDT Effect Of Combination of Morphine+Fentanyl on Emergence Delirium in Patients of Cleft Lip and Palate RepairCondition: Anesthesia Emergence DeliriumInterventions: Drug: MORPHINE PLUS FENTANYL; Drug: Fentanyl Sponsor: Postgraduate Institute of Medical Education and Research Completed Thu, 05 Jan 2017 12:00:00 EST Spinal Bupivacaine/Morphine in Laparoscopic Gastro-intestinal SurgeryCondition: Spinal Bupivacaine/Morphine in Laparoscopic SurgeryInterventions: Drug: Spinal injection bupivacaine/morphine; Drug: subcutaneum injection lidocaine Sponsor: Maasstad Hospital Completed Thu, 06 Nov 2014 12:00:00 EST Intranasal Sufentanil Versus Intravenous Morphine for the Management of Acute PainCondition: Acute PainInterventions: Drug: Sufentanil; Drug: Normal saline; Drug: Morphine Sponsor: The Brooklyn Hospital Center Unknown status Fri, 21 Jul 2017 12:00:00 EDT Randomized Double Blind Controlled Trial Comparing a Blind Sciatic Nerve Block in the Popliteal Fossa to Intravenous Morphine for Traumatic Severe Acute Pain in the Prehospital SettingConditions: Injuries; Pain; EmergenciesInterventions: Drug: Mepivacaine; Drug: Morphine Sponsor: Centre Hospitalier Annecy Genevois Terminated Tue, 31 Jan 2012 12:00:00 EST
Morphine-Sparing Efficacy Of Parecoxib In Pain Treatment After Radical ProstatectomyCondition: Pain, PostoperativeInterventions: Drug: Morphine, Parecoxib; Drug: Morphine, Placebo Sponsor: Pfizer Terminated Thu, 29 Jun 2006 12:00:00 EDT CAUDAL BUPIVACAINE VERSUS INTRAVENOUS MORPHINE ON TIME TO FIRST ANALGESIC REQUIREMENTCondition: Post Operative PainInterventions: Drug: caudal bupivacaine; Drug: intravenous morphine Sponsor: Makerere University Completed Thu, 28 May 2015 12:00:00 EDT Satisfactory Analgesia Minimal Emesis in Day SurgeriesConditions: Pain; Post Operative Nausea and VomitingInterventions: Drug: Morphine; Drug: Hydromorphone Sponsor: McMaster University Completed Fri, 22 Aug 2014 12:00:00 EDT Preemptive Analgesia for Post Tonsillectomy Pain With IV Morphine in ChildrenConditions: Preoperative Sedation; Postoperative PainInterventions: Drug: Morphine premedication; Drug: Midazolam premedication; Drug: Saline premedication (placebo) Sponsor: Dr. Soliman Fakeeh Hospital Unknown status Fri, 16 Dec 2016 12:00:00 EST Morphine and/or Nalbuphine as Adjuvants in Ultrasound Guided Interscalene Block: for Shoulder SurgeriesCondition: Rotator Cuff TearInterventions: Drug: Morphine; Drug: Nalbuphine; Drug: Bupivacaine 0.5%; Drug: Lidocaine Hydrochloride 1% and epinephrine 1:400,000 Sponsor: Assiut University Unknown status Fri, 27 Jan 2017 12:00:00 EST Abuse Potential of Orally Administered Crushed Embeda Compared to Crushed Controlled-Release Morphine and Placebo in Non-Dependent Recreational Opioid UsersCondition: Nondependent Opioid Abuse, EpisodicInterventions: Drug: Placebo; Drug: MS Contin (morphine sulfate, controlled release); Drug: EMBEDA (morphine sulfate / naltrexone hydrochloride) Sponsor: Pfizer Completed Mon, 27 Jun 2011 12:00:00 EDT Opioid Titration With 12.5 ug/h Fentanyl Transdermal Patch vs Orally Morphine for Opioid-naïve Patients With Moderate Cancer PainCondition: Opioid, Moderate Cancer Pain, Transdermal Fentanyl, 12.5ug/h, Opioid-naiveInterventions: Drug: 2.5ug/h transdermal fentanyl; Drug: Oral immediate-released morphine Sponsor: Fujian Cancer Hospital Not yet recruiting Mon, 31 Aug 2020 12:00:00 EDT IV NSAI Versus Nebulized Morphine Analgesia for First-line Renal ColicCondition: Renal ColicInterventions: Drug: IV NSAI; Drug: NM; Drug: IV Serum Saline; Drug: Nebulised Serum Saline Sponsor: University of Monastir Completed Thu, 05 Jun 2014 12:00:00 EDT Femoral/Sciatic Block for Knee SurgeryCondition: Knee InjuriesInterventions: Procedure: femoral nerve blockade; Procedure: morphine Sponsor: University of Sao Paulo General Hospital Completed Mon, 29 Aug 2016 12:00:00 EDT Patient Satisfaction With Subdissociative Dose Ketamine Versus Morphine for Emergency Department Pain ControlCondition: Abdominal PainInterventions: Drug: Ketamine; Drug: Morphine Sponsor: CHRISTUS Health Completed Thu, 07 Jan 2021 12:00:00 EST
QUALITY OF RECOVERY AFTER INTRAOPERATIVE MORPHINE OR METHADONEConditions: Pain, Postoperative; Nausea and Vomiting, PostoperativeInterventions: Drug: Methadone; Drug: Morphine Sponsor: Pontificia Universidade Catolica de Sao Paulo Completed Tue, 07 Feb 2017 12:00:00 EST "Red Morphine Drops" for Symptomatic Treatment of Dyspnoea in Lung CancerConditions: Dyspnea; Lung NeoplasmsInterventions: Drug: Morphine p.o.; Drug: Morphine s.c. Sponsor: Sankt Lukas Hospice Completed Tue, 20 Jun 2006 12:00:00 EDT Combined Epidural Morphine and Midazolam on Postoperative PainCondition: Acute Postoperative PainIntervention: Drug: midazolam Sponsor: Assiut University Recruiting Fri, 26 Jul 2019 12:00:00 EDT Influence of Morphine or Ketamine or Saline Applied During In-hospital Cardiopulmonary Resuscitation on Early SurvivalCondition: Cardiac ArrestInterventions: Drug: Morphine; Drug: Ketamine Injectable Solution; Drug: Saline 0.9% Sponsor: University Hospital, Akershus Not yet recruiting Fri, 05 Jul 2019 12:00:00 EDT Impact of Intrathecal Morphine on Sleep Apnea SyndromeCondition: Sleep Apnea SyndromesInterventions: Drug: Bupivacaine with normal saline; Drug: Bupivacaine with intrathecal morphine Sponsor: Centre Hospitalier Universitaire Vaudois Completed Fri, 02 Oct 2015 12:00:00 EDT Embrace TDD: Post-Market Study to Evaluate Intrathecal Morphine as an Alternative to Systemic Opioids for Chronic PainConditions: Chronic Non-malignant Pain; Chronic Pain; Pain, Back; Pain, LegInterventions: Device: Medtronic SynchroMed™ II infusion system; Drug: Preservative-free morphine sulfate (PFMS) Sponsor: MedtronicNeuro Active, not recruiting Mon, 03 Dec 2018 12:00:00 EST Prediction of Inter-individual Differences in the Response to Morphine Versus Milnacipran in Patients With SciaticaCondition: Neuropathic PainInterventions: Drug: Morphine; Drug: Milnacipran Sponsor: Rambam Health Care Campus Unknown status Thu, 01 Aug 2013 12:00:00 EDT Morphine Versus Methadone for Opiate Exposed Infants With Neonatal Abstinence SyndromeCondition: Neonatal Abstinence SyndromeInterventions: Drug: Morphine; Drug: Methadone Sponsor: University of New Mexico Unknown status Mon, 01 Aug 2016 12:00:00 EDT Morphine for Dyspnea in Pulmonary FibrosisCondition: Idiopathic Pulmonary Fibrosis (IPF)Interventions: Drug: Morphine hydrochloride; Drug: Placebo Sponsor: Medical University of Gdansk Not yet recruiting Tue, 04 Aug 2020 12:00:00 EDT Pramipexole and Morphine for Renal ColicCondition: Renal ColicInterventions: Drug: Pramipexole; Drug: Morphine; Drug: Placebo oral tablet Sponsor: East Carolina University Recruiting Wed, 13 Nov 2019 12:00:00 EST
A Multicenter, Randomized, Open-Label, Parallel-Group Trial to Compare the Efficacy and Safety of the Sufentanil NanoTab PCA System/15 mcg (Zalviso™)to Intravenous Patient-Controlled Analgesia With Morphine for the Treatment of Acute Post-Operative PainCondition: Post-Operative PainInterventions: Drug: Sufentanil NanoTab PCA System/15 mcg; Drug: morphine IV PCA Sponsor: AcelRx Pharmaceuticals, Inc. Completed Mon, 27 Feb 2012 12:00:00 EST Analgesic Efficacy of (MSIR)/Acetaminophen vs. Oxycodone/Acetaminophen (Percocet)Condition: Pain ManagementInterventions: Drug: Morphine Sulfate; Drug: Oxycodone; Drug: Acetaminophen Sponsor: Antonios Likourezos Completed Thu, 23 Mar 2017 12:00:00 EDT Comparison of Epidural Oxycodone and Epidural MorphineCondition: PruritusInterventions: Drug: Opioid administration oxycodone; Drug: Opioid administration morphine Sponsor: KK Women's and Children's Hospital Completed Wed, 29 Oct 2014 12:00:00 EDT Pre- Versus Post-Incisional Epidural Morphine: Higher Postoperative Pain Perception and Extra Morphine ConsumptionCondition: PainIntervention: Drug: normal saline 3 ml, morphine 3mg Sponsor: Tel-Aviv Sourasky Medical Center Completed Tue, 30 Mar 2010 12:00:00 EDT Intravenous Paracetamol or Morphine for the Treatment of Acute Flank PainCondition: UrolithiasisInterventions: Drug: paracetamol; Drug: morphine; Drug: Paracetamol; Drug: Morphine Sponsor: Pamukkale University Completed Fri, 18 Mar 2011 12:00:00 EDT Effect of Topical Morphine (Mouthwash) on Oral Pain Due to Chemo- and/or Radiotherapy Induced MucositisConditions: Cancer; MucositisInterventions: Drug: mouth wash with morphine; Drug: placebo Sponsor: University Hospital, Geneva Completed Wed, 13 Feb 2008 12:00:00 EST Effects of a Single Dose of Egalet® Morphine Combined With a Single Dose of Alcohol in Healthy Moderate DrinkersCondition: PainIntervention: Drug: Morphine sulphate Sponsor: Egalet Ltd Completed Thu, 04 Dec 2008 12:00:00 EST Randomized Control Trial of Buprenorphine vs. Morphine for the Treatment of Neonatal Opioid Withdrawal Syndrome (NOWS)Condition: Neonatal Opioid Withdrawal SyndromeInterventions: Drug: Buprenorphine or Placebo; Drug: Morphine or Placebo Sponsors: Women and Infants Hospital of Rhode Island; National Institute of General Medical Sciences (NIGMS) Not yet recruiting Thu, 02 Jul 2020 12:00:00 EDT Efficacy of Multimodal Opioid Therapy During Hepatic Resection SurgeryConditions: Liver Dysfunction; PainInterventions: Drug: Morphine sulphate; Drug: Morphine hydrochloride, remifentanil hydrochloride Sponsor: St Vincent's University Hospital, Ireland Unknown status Sun, 04 Nov 2007 12:00:00 EDT Effect of Methylnaltrexone on the PK/PD Profiles of Ticagrelor in Patients Treated With MorphineCondition: Coronary Artery DiseaseInterventions: Drug: Methylnaltrexone; Other: Placebo; Drug: Morphine; Drug: Ticagrelor Sponsor: University of Florida Completed Tue, 31 Mar 2015 12:00:00 EDT
Methadone Versus Morphine for Orthopedic Surgery PatientsConditions: Fracture; Pain, PostoperativeInterventions: Drug: Methadone; Drug: Morphine Sponsor: University of Louisville Completed Mon, 04 May 2009 12:00:00 EDT Comparison of One Morphine Sulfate Sustained-Release 200mg Capsule With Two 100 mg KADIAN Capsules Under Fasting ConditionsCondition: HealthyInterventions: Drug: morphine sulfate sustained-release capsules; Drug: KADIAN (morphine sulfate sustained-release) capsules Sponsor: Actavis Inc. Completed Thu, 25 Sep 2008 12:00:00 EDT Comparison of One Morphine Sulfate Sustained-Release 200mg Capsule With Two 100 mg KADIAN Capsules Under Fed ConditionsCondition: HealthyInterventions: Drug: morphine sulfate sustained-release capsules; Drug: KADIAN Sponsor: Actavis Inc. Completed Thu, 25 Sep 2008 12:00:00 EDT Visual Pain Score and Perfusion Index in Postoperative PatientsCondition: PerfusionIntervention: Drug: Morphine Sponsor: Tokat Gaziosmanpasa University Completed Fri, 12 May 2017 12:00:00 EDT Effect of Morphine, Tramadol, and Ketorolac on Postoperative Stress and Immune ResponsesCondition: Breast CancerInterventions: Drug: Intravenous morphine sulphate; Drug: Intravenous tramadol HCL; Drug: Intravenous ketorolac tromethamine Sponsor: Assiut University Unknown status Thu, 21 May 2015 12:00:00 EDT Comparison of Morphine and Fentanyl/Midazolam in Intensive Care UnitCondition: Respiratory FailureInterventions: Drug: Morphine infusion; Drug: Fentanyl and Midazolam infusion Sponsor: Clínica de Los Andes IPS Completed Mon, 21 May 2012 12:00:00 EDT The Analgesic Efficacy of Local Anaesthetic Wound Infiltration Versus Intrathecal Morphine for Total Knee ReplacementCondition: Total Knee ReplacementInterventions: Drug: Levobupivacaine; Drug: Intrathecal morphine Sponsor: Cork University Hospital Unknown status Thu, 10 Mar 2011 12:00:00 EST The Intrathecal Morphine for NephrectomyCondition: Renal Cell CarcinomaInterventions: Drug: The intrathecal morphine injection; Drug: The intravenous patient-controlled analgesia; Drug: Demerol on demand Sponsor: Seoul National University Hospital Completed Thu, 28 Nov 2013 12:00:00 EST Spinal Morphine in Robotic Assisted Radical ProstatectomyConditions: Morphine; Injections, Spinal; Prostatectomy; Patient SatisfactionInterventions: Drug: Morphine; Drug: Lidocaine Sponsor: Maasstad Hospital Completed Wed, 05 Oct 2016 12:00:00 EDT Comparison of Two Analgesic Strategies After Scheduled CaesareanCondition: AnalgesiaInterventions: Drug: Rachianesthesia; Drug: Sodium Chloride Injection; Drug: Morphine Sponsor: GCS Ramsay Santé pour l'Enseignement et la Recherche Recruiting Tue, 16 Feb 2021 12:00:00 EST
Buprenorphine for Treatment of Neonatal Abstinence Syndrome in Infants With In Utero Exposure to BenzodiazepinesCondition: Neonatal Abstinence SyndromeInterventions: Drug: oral morphine; Drug: sublingual buprenorphine Sponsor: Thomas Jefferson University Completed Thu, 23 Aug 2012 12:00:00 EDT Analgesia and Wound Healing Assessment Following Topical Morphine Applied to Patients With Cutaneous Cancer Related PainConditions: Ulcer; Wounds and InjuriesIntervention: Drug: topical morphine Sponsors: Soroka University Medical Center; Israel Cancer Association Withdrawn Wed, 22 Mar 2006 12:00:00 EST Abuse Potential Assessment of Intranasally Administered EMBEDA Compared To Morphine Sulfate Controlled Release And PlaceboConditions: Narcotic Abuse; Opioid-related Disorders; Analgesia; Chronic PainInterventions: Drug: Placebo; Drug: EMBEDA - morphine sulfate/ naltrexone hydrochloride; Drug: morphine sulfate CR crushed. Sponsor: Pfizer Completed Thu, 10 May 2012 12:00:00 EDT Comparison of the Analgesic Effect Between Intrathecal Morphine and IV-fentanyl Patient Controlled Analgesia (ITM-IVPCA) and Epidural PCA (PCEA) in Patients Undergoing Gastrectomy -Randomized Allocation Study-Condition: Gastric CancerInterventions: Drug: morphine; Drug: Ropivacaine Sponsor: Yonsei University Completed Thu, 04 Nov 2010 12:00:00 EDT Magnetic Seizure Therapy In Bipolar Depression (MST-BpD)Condition: Bipolar DisorderInterventions: Device: MST; Device: ECT Sponsor: The University of Texas Health Science Center, Houston Recruiting Fri, 06 Sep 2019 12:00:00 EDT Long Thoracic Nerve Blockade for Pain Treatment After Video-Assisted Thoracoscopic SurgeryConditions: Nerve Block; Video-Assisted Thoracic SurgeryInterventions: Drug: Morphine Sulfate; Drug: Bupivacaine Sponsor: Bursa Yüksek İhtisas Education and Research Hospital Unknown status Fri, 30 Mar 2018 12:00:00 EDT Use of Intrathecal Hydromorphone in Elective Cesarean DeliveriesCondition: PainInterventions: Drug: Hydromorphone; Drug: Morphine Sponsors: Grace Shih, MD; Masimo Corporation Completed Fri, 31 May 2013 12:00:00 EDT Vital Signs-Integrated Patient-Assisted Intravenous Opioid Analgesia for Post Surgical PainConditions: Pain; Respiratory DepressionInterventions: Device: VPIA pump; Drug: Morphine Sponsor: KK Women's and Children's Hospital Recruiting Mon, 08 Jul 2019 12:00:00 EDT Bioavailability and Effectiveness of Transdermally Administered MorphineConditions: Cancer; PainIntervention: Drug: morphine Sponsors: Alberta Health Services; Tom Baker Cancer Centre Completed Tue, 02 Aug 2005 12:00:00 EDT Inflammatory Responses to Acute and Chronic Opioid Exposure in HumansCondition: InflammationIntervention: Drug: Morphine Sulfate Sponsor: Stanford University Terminated Mon, 17 Dec 2012 12:00:00 EST
Comparison of Intrathecal Morphine With the Quadratus Lumborum Type 2 Block for Post-operative Analgesia Following Elective Caesarean Section (QLBvITM Study)Conditions: Cesarean Section; Pain, AcuteInterventions: Procedure: Intrathecal morphine as well as local anaesthetic in Blocks; Procedure: Intrathecal morphine as well as saline in Block; Procedure: Saline intrathecal as well as saline in Blocks; Procedure: Saline intrathecal as well as local anaesthetic in Blocks Sponsors: Dr Willem Basson; Sunshine Coast Hospital and Health Service Withdrawn Wed, 30 Aug 2017 12:00:00 EDT Intermittent Epidural Bolus Versus Epidural Infusion for Posterior Spinal Fusion After Adolescent Idiopathic ScoliosisCondition: PainInterventions: Drug: Intermittent bolus epidural morphine; Drug: continuous epidural morphine Sponsor: Inonu University Completed Fri, 29 Jan 2016 12:00:00 EST A Health Economic Trial in Adult Patients Undergoing Open Colectomy MA402S23B301Condition: Bowel ObstructionInterventions: Drug: morphine sulfate; Drug: bupivacaine liposome extended-release injectable suspension Sponsors: Pacira Pharmaceuticals, Inc; Registrat-Mapi Terminated Tue, 10 Jan 2012 12:00:00 EST A Randomized, Double-blind Comparison of Morphine and Sufentanil for Prehospital Traumatic Severe Acute PainCondition: Acute PainInterventions: Drug: Sufentanil; Drug: Morphine Sponsor: University Hospital, Toulouse Completed Fri, 11 Apr 2008 12:00:00 EDT Comparison of One Morphine Sulfate Sustained-Release 200 mg Capsule With Two 100 mg KADIAN Capsules on ApplesauceCondition: HealthyInterventions: Drug: morphine sulfate sustained-release capsules; Drug: KADIAN (morphine sulfate sustained-release) capsules Sponsor: Actavis Inc. Completed Thu, 25 Sep 2008 12:00:00 EDT Geriatric Ketamine for Pain Management StudyCondition: PainInterventions: Drug: Morphine; Drug: Ketamine Sponsor: Antonios Likourezos Completed Wed, 03 Feb 2016 12:00:00 EST Non-Opiate Treatment After Prenatal Opiate Exposure to Prevent Postnatal Injury to the Young BrainCondition: Neonatal Abstinence SyndromeInterventions: Drug: Clonidine; Drug: Morphine Sponsors: Henrietta Bada; National Institute on Drug Abuse (NIDA) Recruiting Thu, 11 Jan 2018 12:00:00 EST Intrathecal Morphine for Radical Robot Assisted Prostatectomy (TORNADO)Condition: Catheter Related ComplicationInterventions: Drug: intrathecal infusion; Drug: Intravenous Infusion; Drug: Ropivacaine injection Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS Completed Wed, 24 Mar 2021 12:00:00 EDT Efficacy of Intranasal Fentanyl at Reducing Pain During Abscess Incision and Drainage (I&D) in ChildrenConditions: Abscess; PainInterventions: Drug: Intranasal Fentanyl; Drug: Intravenous Morphine Sponsor: Columbia University Completed Thu, 08 Mar 2012 12:00:00 EST Vital-signs-integrated Patient-assisted Intravenous Opioid AnalgesiaCondition: Respiratory DepressionInterventions: Device: VPIA analgesia; Drug: Morphine Sponsor: KK Women's and Children's Hospital Active, not recruiting Fri, 17 Jun 2016 12:00:00 EDT
Buprenorphine for the Treatment of Neonatal Abstinence SyndromeCondition: Neonatal Abstinence SyndromeInterventions: Drug: buprenorphine; Drug: Oral morphine solution Sponsors: Thomas Jefferson University; National Institute on Drug Abuse (NIDA) Completed Mon, 27 Aug 2007 12:00:00 EDT Intra Nasal Sufentanil Versus Intravenous Morphine for Acute Severe Traumatic Pain Analgesia in Emergency SettingConditions: Severe Traumatic Pain; Numeric Pain Rating Scale > 5 / 10Interventions: Drug: Morphine; Drug: Sufentanil; Drug: Placebo Sponsors: University Hospital, Grenoble; Fondation Apicil; SFMU Completed Mon, 24 Mar 2014 12:00:00 EDT Cannabidiol, Morphine, PainConditions: CBD; Chronic PainInterventions: Drug: Immediate-release Oral Morphine Sulfate Tablets; Other: Thermal and Pressure Nociceptive Sensitivity Sponsor: Wayne State University Recruiting Wed, 24 Jul 2019 12:00:00 EDT Comparison of A Single Dose Combination of Methadone and Morphine With Morphine Alone for Treating Post-operative PainCondition: PainInterventions: Drug: Methadone; Drug: methadone and morphine Sponsor: Memorial Sloan Kettering Cancer Center Completed Fri, 02 Sep 2005 12:00:00 EDT Postoperative Urinary Retention in Orthopedic PatientsConditions: Urinary Retention; Anesthesia, Spinal; Orthopedic Procedures; Nerve BlockInterventions: Procedure: spinal anesthesia with morphine; Procedure: spinal anesthesia without morphine + peripheral nerve block Sponsor: Hospital de Clinicas de Porto Alegre Completed Fri, 06 Mar 2020 12:00:00 EST Incidence of Brachial Plexus Injury After Rotator Cuff Repair With Continuous Interscalene BlockCondition: Brachial Plexus InjuryInterventions: Procedure: Continuous interscalene block; Procedure: PCA morphine Sponsor: Centre Hospitalier Universitaire Vaudois Withdrawn Wed, 13 Apr 2011 12:00:00 EDT Comparison of Two KADIAN 10 mg Capsules to a KADIAN 20 mg Capsule Under Fed ConditionsCondition: HealthyInterventions: Drug: morphine sulfate extended-release capsules; Drug: KADIAN (morphine sulfate extended-release) capsules Sponsor: Actavis Inc. Completed Thu, 25 Sep 2008 12:00:00 EDT Anti-suicidal Effects of Buprenorphine in Opioid Use DisorderConditions: Opioid-use Disorder; Suicidal IdeationInterventions: Drug: Buprenorphine/Naloxone 8/2 milligram (mg) Sublingual Film; Drug: Morphine Sulfate 30 mg Sponsor: New York State Psychiatric Institute Withdrawn Tue, 21 Jan 2020 12:00:00 EST Clonidine and Morphine in Caudal AnesthesiaCondition: Postoperative PainInterventions: Drug: Clonidine; Drug: Morphine; Drug: Bupivacaine plus clonidine and morphine; Drug: Bupivacaine Sponsors: Federal University of Minas Gerais; Santa Casa de Misericórdia de Belo Horizonte Completed Tue, 06 May 2008 12:00:00 EDT Efficacity, Safety and Cost of Intravenous Morphine Titration Alone or Combined to KetamineCondition: Postoperative PainIntervention: Drug: Ketamine Sponsor: Assistance Publique - Hôpitaux de Paris Completed Thu, 17 Jun 2010 12:00:00 EDT
Comparison of Two KADIAN 10 mg Capsules to a KADIAN 20 mg Capsule Under Fasted ConditionsCondition: HealthyInterventions: Drug: morphine sulfate extended-release capsules; Drug: KADIAN (morphine sulfate extended-release) capsules Sponsor: Actavis Inc. Completed Thu, 25 Sep 2008 12:00:00 EDT Morphine in Acute Abdominal PainCondition: Abdominal PainIntervention: Drug: Morphine Sponsor: Akdeniz University Completed Wed, 28 Apr 2010 12:00:00 EDT A Comparison of the Addiction Liability of Hydrocodone and Sustained Release MorphineCondition: Chronic PainInterventions: Behavioral: Markers of Abuse Liability, Neuropsych Testing, and Cue Reactivity; Drug: ER Morphine; Drug: hydrocodone plus acetaminophen; Drug: placebo Sponsor: University of California, Davis Completed Thu, 13 Apr 2006 12:00:00 EDT Management of Pain Post Hepatectomy : Infiltration of Local Anesthetics Versus Continuous Spinal Analgesia .Condition: Pain, PostoperativeInterventions: Drug: intrathecal morphine; Drug: Morphine PCA; Drug: Ropivacaine infiltration Sponsor: University Hospital, Lille Active, not recruiting Thu, 03 Aug 2017 12:00:00 EDT Comparison of the Safety of Q8003 Versus Morphine Equivalent Doses of Its Components (Oxycodone and Morphine) in Bunionectomy PatientsCondition: Postoperative PainInterventions: Drug: Q8003 (morphine sulfate and oxycodone hydrochloride); Drug: Morphine sulfate; Drug: Oxycodone HCl Sponsor: QRxPharma Inc. Completed Thu, 20 Jan 2011 12:00:00 EST Safety and Efficacy of Intrathecally Administered Magnesium SulfateConditions: Abdominal Cancer; Abdominal PainInterventions: Procedure: intrathecal morphine+LA; Procedure: intrathecal morphine+LA+ Mg sulp. 50; Procedure: intrathecal morphine+LA+ Mg sulp. 100 Sponsor: South Egypt Cancer Institute Completed Thu, 08 Mar 2018 12:00:00 EST Topical Morphine for Stomatitis-related Pain Induced by ChemotherapyConditions: Pain; MucositisInterventions: Drug: morphine solution for injection; Drug: Placebo; Drug: morphine mouthwash Sponsors: Danish University of Pharmaceutical Sciences; Copenhagen University Hospital, Denmark Completed Fri, 28 Jul 2006 12:00:00 EDT Drug Drug Interaction Study With Gabapentin Enacarbil and MorphineCondition: Restless Legs SyndromeInterventions: Drug: morphine Placebo; Drug: GEn 600 mg; Drug: Morphine; Drug: GEn Placebo Sponsor: XenoPort, Inc. Completed Tue, 22 Nov 2011 12:00:00 EST A Health Economic Trial in Adult Patients Undergoing Open Colectomy MA402S23B302Condition: Bowel ObstructionInterventions: Drug: IV morphine sulfate; Drug: EXPAREL (bupivacaine liposome injectable suspension) Sponsors: Pacira Pharmaceuticals, Inc; Registrat-Mapi Terminated Tue, 10 Jan 2012 12:00:00 EST Local Infiltration Analgesia or Intrathecal Morphine in Total Knee ArthroplastyCondition: OsteoarthritisInterventions: Drug: ropivacaine, ketorolac and epinephrine; Drug: morphine Sponsor: Region Örebro County Unknown status Thu, 08 Oct 2009 12:00:00 EDT
A Study to Evaluate the Effectiveness and Safety of CG5503 (Tapentadol) in the Treatment of Chronic Tumor Related Pain Compared With Placebo and MorphineConditions: Pain; Neoplasm; CancerInterventions: Drug: Tapentadol in the Titration Phase; Drug: Morphine in the Maintenance Phase; Drug: Matching Placebo in the Maintenance Phase after Tapentadol in the Titration Phase; Drug: Tapentadol in the Maintenance Phase; Drug: Morphine in the Titration Phase Sponsors: Grünenthal GmbH; Johnson & Johnson Pharmaceutical Research & Development, L.L.C. Terminated Mon, 23 Jul 2007 12:00:00 EDT Tramadol Versus Placebo and Morphine in the Management of Post-Operative Pain AbdominoplastyCondition: Pain ManagementInterventions: Drug: Tramadol; Drug: Morphine; Other: Placebo Sponsor: Avenue Therapeutics, Inc. Active, not recruiting Thu, 13 Dec 2018 12:00:00 EST The Effect of Intravenous Nalbuphine on PONV With Intrathecal Morphine in Abdominoplasty.Condition: Abdominal ObesityInterventions: Drug: Intrathecal Morphine; Drug: Intrathecal Morphine + Intravenous Nalbuphine Sponsor: Assiut University Unknown status Wed, 26 Dec 2018 12:00:00 EST The Analgesic Effect of Combined Treatment With Intranasal S-ketamine and Intranasal MidazolamConditions: Analgesia, Patient-controlled; Spinal StenosisInterventions: Drug: s-ketamine & midazolam; Drug: Morphine PCA Sponsor: University Hospital, Basel, Switzerland Completed Wed, 12 Jan 2011 12:00:00 EST A Study to Evaluate Tapentadol (CG5503) in the Treatment of Chronic Tumor-Related Pain Compared With Placebo and MorphineConditions: Tumor; PainInterventions: Drug: Tapentadol Extended Release; Drug: Matching Placebo after Tapentadol in the Titration Phase.; Drug: Morphine Sulphate Controlled Release Sponsors: Grünenthal GmbH; Johnson & Johnson Pharmaceutical Research & Development, L.L.C. Completed Fri, 11 May 2007 12:00:00 EDT Postoperative Pain Therapy With Hydromorphone TCI-PCA vs. Morphine PCACondition: Acute Postoperative PainInterventions: Drug: Hydromorphone; Drug: Morphine Sponsors: University of Erlangen-Nürnberg Medical School; German Federal Ministry of Education and Research Completed Fri, 26 Jun 2015 12:00:00 EDT Efficacy of Transdermal Fentanyl Patches in Relief of Acute Postoperative Pain After MastectomyCondition: Breast Cancer FemaleInterventions: Drug: The Transdermal Therapeutic System-Fentanyl (TTS-F); Device: Intravenous patient-controlled analgesia (PCA) morphine Sponsor: South Egypt Cancer Institute Unknown status Mon, 13 Feb 2017 12:00:00 EST Combination Trial of Intravenous Paracetamol - Morphine for Treating Acute Renal Colic in Emergency Setting: An Optimum TreatmentCondition: Renal ColicInterventions: Drug: Paracetamol+Morphine; Drug: Dexketoprofen plus Morphine; Drug: Placebo plus Morphine Sponsor: Akdeniz University Completed Wed, 06 Mar 2019 12:00:00 EST Dexmedetomidine for Postoperative Analgesia After Bariatric SurgeryConditions: Obesity; Sleep Apnea; Diabetes; HypertensionInterventions: Drug: Dexmedetomidine; Drug: Morphine Sponsor: American University of Beirut Medical Center Completed Mon, 11 Aug 2014 12:00:00 EDT Quadratus Lumborum in Cesarean Section TrialCondition: Postoperative AnalgesiaIntervention: Procedure: Quadratus Lumborum Block Sponsor: University of Sao Paulo General Hospital Unknown status Mon, 17 Sep 2018 12:00:00 EDT
A Pharmacokinetic (PK) Study of Extended-Release Epidural Morphine in Upper Abdominal SurgeryCondition: Postoperative PainIntervention: Drug: DepoDur (extended-release epidural morphine) Sponsors: EKR Therapeutics, Inc; Pacira Pharmaceuticals, Inc Completed Wed, 06 Aug 2008 12:00:00 EDT Very Low Dose Caudal Morphine for Postoperative Pain ManagementCondition: Caudal AnesthesiaIntervention: Procedure: Caudal block Sponsor: University of Oklahoma Completed Tue, 14 Jul 2009 12:00:00 EDT A Comparison of Analgesic Efficacy Between a Single Dose of ORG 28611, Morphine, and Placebo After Dental Impaction Surgery (Study P05800)Condition: AnalgesiaInterventions: Drug: Org 28611; Drug: morphine sulfate; Drug: Placebo Sponsor: Merck Sharp & Dohme Corp. Terminated Fri, 31 Oct 2008 12:00:00 EDT Efficacy of Intravenous Ibuprofen and Paracetamol on Postoperative Pain and Morphine Consumption in Lumbar Disc SurgeryCondition: Postoperative Pain ManagementInterventions: Drug: Morphine Sulfate; Drug: Intravenous paracetamol; Drug: Intravenous ibuprofen Sponsor: Inonu University Completed Mon, 19 Feb 2018 12:00:00 EST Effect of Early Morphine Administration on the Development of Acute Opioid Tolerance During Pediatric Scoliosis SurgeryCondition: ScoliosisInterventions: Drug: Morphine; Other: Saline Sponsor: The Hospital for Sick Children Completed Wed, 20 Aug 2008 12:00:00 EDT A Study of OROS Hydromorphone HCL vs Morphine in Cancer Pain Patients.Conditions: Pain; Analgesics, OpioidIntervention: Drug: OROS hydromorphone HCL ; Morphine sulfate Sponsor: Alza Corporation, DE, USA Completed Wed, 13 Dec 2006 12:00:00 EST Pain Medicine for Wound Care ProceduresConditions: Wound Care; Pain Intensity; Hyperalgesia; Nausea; Vomiting; HallucinationsInterventions: Drug: morphine plus saline; Drug: morphine plus ketamine Sponsor: University of California, San Francisco Completed Thu, 19 Jun 2008 12:00:00 EDT Ticagrelor and Intracoronary Morphine in Patients Undergoing Primary Percutaneous Coronary InterventionCondition: ST-Segment Elevation Myocardial InfarctionInterventions: Drug: Ticagrelor; Drug: Clopidogrel; Drug: Morphine Sulfate; Drug: Saline Sponsor: Hyeon-Cheol Gwon Unknown status Fri, 30 Nov 2012 12:00:00 EST Postoperative Pain Control After Hip Hemiarthroplasty: Intrathecal Morphine vs Periarticular Infiltration of BupivacaineCondition: Femoral Neck FractureInterventions: Drug: morphine; Other: control; Drug: Bupivacaine Sponsor: Mahidol University Terminated Wed, 13 Oct 2010 12:00:00 EDT Measurement of the Efficacy of MORPHINE in the Early Management of Dyspnea in COVID-19 Positive PatientsConditions: Patients Hospitalized in the Hospices Civils of Lyon; COVID-19 Disease; Moderate to Severe Dyspnea; Without Resuscitation Objective ManagementIntervention: Other: No intervention / Compare the difference in respiratory rate between H0 and H12 of the initiation of morphine between the control and interventional groups Sponsor: Hospices Civils de Lyon Recruiting Fri, 21 Aug 2020 12:00:00 EDT
Role of Methadone As Co-Opioid AnalgesicCondition: PainInterventions: Drug: Morphine; Drug: Methadone Sponsor: M.D. Anderson Cancer Center Terminated Thu, 15 Nov 2007 12:00:00 EST Extended-release Epidural Morphine for Acute Post-operative Analgesia Following Selective Dorsal Rhizotomy in ChildrenCondition: Spastic Cerebral PalsyInterventions: Drug: Extended-release Epidural morphine (EREM) 80; Drug: Extended-release Epidural Morphine (EREM) 120; Drug: Control: Saline Sponsor: Washington University School of Medicine Terminated Mon, 10 Aug 2009 12:00:00 EDT Spinal Analgesia for Colonic Resection Using an Enhanced Recovery After Surgery (ERAS) ProgramConditions: Colon Cancer; Inflammatory Bowel Diseases; DiverticulitisInterventions: Drug: Spinal analgesia; Drug: Patient Control Analgesia (PCA) Morphine Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre Completed Tue, 22 Nov 2011 12:00:00 EST Morphine Titration by Patient Self-controlled by a Mechanical Device Versus Administration by the Nurse for Patients With Severe Acute Pain in the Emergency DepartmentCondition: Acute PainIntervention: Device: Titration of morphine by Patient Controlled Analgesy Sponsor: University Hospital, Angers Completed Mon, 02 Jun 2014 12:00:00 EDT Postoperative Pain Control After Kidney Surgery : a Comparison of Intrathecal Morphine Plus PCA and PCA OnlyCondition: Postoperative PainIntervention: Drug: spinal morphine Sponsor: Khon Kaen University Unknown status Tue, 20 Sep 2005 12:00:00 EDT Magnetic Seizure Therapy for the Treatment of Borderline Personality DisorderCondition: Borderline Personality DisorderInterventions: Device: MagPro MST with Cool TwinCoil; Behavioral: DBT Sponsor: Centre for Addiction and Mental Health Active, not recruiting Tue, 05 Dec 2017 12:00:00 EST Efficacy of Intravenous Paracetamol and Ibuprofen on Postoperative Pain and Morphine Consumption in HysterectomyCondition: Postoperative Pain ManagementInterventions: Drug: Morphine Sulfate; Drug: Intravenous paracetamol; Drug: Intravenous ibuprofen; Drug: Morphine Sponsor: Inonu University Enrolling by invitation Thu, 31 Dec 2020 12:00:00 EST Ibuprofen and Opioid (Morphine or Diamorphine) for Acute Pain in Sickle Cell Disease - Sickle With Ibuprofen & MorphineCondition: Sickle Cell DiseaseInterventions: Drug: Ibuprofen; Drug: Placebo; Drug: Diamorphine or Morphine Sponsors: London North West Healthcare NHS Trust; Medical Research Council CTU Terminated Mon, 13 Apr 2009 12:00:00 EDT Morphine Mouthwash for Management of Oral Mucositis in Patients With Head and Neck CancerCondition: StomatitisInterventions: Drug: 2% morphine solution; Drug: Magnesium aluminum hydroxide; Drug: 2% viscous lidocaine; Drug: Diphenhydramine Sponsor: Isfahan University of Medical Sciences Completed Tue, 23 Apr 2013 12:00:00 EDT Evaluation of Preoperative Use of Pregabalin on Postoperative Analgesia After Laparoscopic Colorectal SurgeryCondition: Postoperative PainInterventions: Drug: Pregabalin; Drug: Placebo; Drug: Morphine Sponsors: Larissa University Hospital; University of Thessaly Completed Thu, 12 Sep 2013 12:00:00 EDT
Parent/Nurse Controlled Analgesia in the Neonatal Intensive Care UnitConditions: Abdominal Surgery; Thoracic SurgeryIntervention: Drug: Morphine Sponsors: Medical College of Wisconsin; Children's Hospital and Health System Foundation, Wisconsin Completed Thu, 04 Apr 2013 12:00:00 EDT Intrathecal Ketorolac in Patients With Intrathecal Morphine Dose EscalationCondition: PainInterventions: Drug: ketorolac; Drug: morphine Sponsor: Wake Forest University Health Sciences Withdrawn Fri, 07 Jul 2006 12:00:00 EDT Analgesic Tolerance to Repeated Doses of Subcutaneous MorphineCondition: Healthy VolunteersIntervention: Drug: intramuscular injections of morphine Sponsor: University of California, San Francisco Completed Mon, 21 Nov 2005 12:00:00 EST Paravertebral Morphine Versus Dexmedetomidine on Acute and Chronic Postmastectomy PainConditions: Acute Pain; Chronic PainInterventions: Drug: bupivicaine; Drug: morphine; Drug: Dexmedetomidine Sponsor: Assiut University Unknown status Tue, 18 Oct 2016 12:00:00 EDT A Safety and Efficacy Study of Sufentanil Transdermal System in Patients With Chronic Pain Due to CancerCondition: Chronic PainInterventions: Drug: Sufentanil; Drug: Sustained Release Morphine Sulfate Sponsor: Labtec GmbH Withdrawn Wed, 22 Jul 2009 12:00:00 EDT A Study Comparing Recurrent Use of MSIR, Percocet, and Vicodin at Discharge From the EDCondition: PainInterventions: Drug: Morphine Sulfate Immediate Release; Drug: Oxycodone/Acetaminophen; Drug: Hydrocodone/Acetaminophen Sponsor: Antonios Likourezos Withdrawn Fri, 18 May 2018 12:00:00 EDT Morphine Slow-release Capsules in Substitution TherapyCondition: Opiate DependentInterventions: Drug: Sevre-Long™; Drug: Slow release oral morphine; Drug: Methadone Sponsor: Mundipharma Medical Company Completed Tue, 02 Mar 2010 12:00:00 EST A Prospective Comparison of Methadone, Fentanyl, and Morphine for Post-laparotomy Epidural AnalgesiaCondition: Post Laparotomy Pain TreatmentInterventions: Drug: epidural morphine via PCEA; Drug: epidural fentanyl via PCEA; Drug: epidural methadone via PCEA; Drug: intravenous morphine via PCA Sponsor: Hadassah Medical Organization Unknown status Thu, 11 Apr 2013 12:00:00 EDT Intrathecal Opioids for Colorectal ResectionConditions: Colorectal Surgery; Pain, Postoperative; Analgesic, OpioidInterventions: Drug: Morphine; Drug: Hydromorphone Sponsor: Mayo Clinic Recruiting Fri, 12 Feb 2021 12:00:00 EST Translation and Validation of the German Version of the Toronto Extremity Salvage Score (TESS) and Musculoskeletal Tumor Society (MSTS)Condition: SarcomaIntervention: Other: Questionaire TESS and MSTS Sponsor: Medical University Innsbruck Not yet recruiting Tue, 31 Mar 2020 12:00:00 EDT
Comparative Pain Control Between 0.2 or 0.3 Spinal Morphine and 0.25 or 0.5 % Bupivacaine for FNB After TKAConditions: Post Operative Pain; Total Knee ReplacementInterventions: Drug: morphine and bupivacaine; Drug: spinal morphine and marcaine Sponsors: Mahidol University; Siriraj Hospital Completed Fri, 21 Nov 2008 12:00:00 EST Quadratus Lumborum Block for Post-Cesarean AnalgesiaCondition: Postoperative PainInterventions: Procedure: Quadratus Lumborum Block; Procedure: Sham Block; Drug: Intrathecal Morphine; Drug: Intrathecal Saline Sponsor: Lawson Health Research Institute Unknown status Thu, 15 Jan 2015 12:00:00 EST Investigating the Safety of Post-surgical Analgesics in Children With Obstructive Sleep ApneaCondition: Pediatric Obstructive Sleep Apnea SyndromeInterventions: Drug: Morphine; Drug: Ibuprofen Sponsors: Hamilton Health Sciences Corporation; The Hospital for Sick Children; University of Western Ontario, Canada Unknown status Fri, 07 Sep 2012 12:00:00 EDT NEUROIMPA - Intraarticular Application of Opioids in Chronic Arthritis of the Knee JointCondition: Knee ArthritisInterventions: Drug: Morphine Sulfate; Drug: Triamcinolone; Drug: placebo Sponsors: Hildrun Haibel; DLR German Aerospace Center Active, not recruiting Fri, 18 Nov 2016 12:00:00 EST Comparison of Oral Morphine Versus Nasal Ketamine Spray With Chitosan in Cancer Pain OutpatientsConditions: Cancer: Breakthrough Pain; Cancer: Extreme Pain on MovementInterventions: Drug: Morphine; Drug: Ketamine; Drug: Placebo; Drug: Chitosan Sponsor: University Hospital, Basel, Switzerland Terminated Thu, 29 Oct 2015 12:00:00 EDT Magnetic Seizure Therapy (MST) for Severe Mood DisorderCondition: DepressionInterventions: Device: Thymatron; Device: Magstim Theta Sponsors: Sarah Lisanby; Duke University; University of Texas Southwestern Medical Center; Stanley Medical Research Institute Completed Wed, 20 Jun 2007 12:00:00 EDT Double Blind Randomized, Monocentric, Cross-over, Placebo-controlled Study to Evaluate the Effect of Morphine and Naloxone on Motivation (MBBAnalgesic)Condition: HealthyInterventions: Drug: 50 mL of sodium chloride (0,9%); Drug: Morphine 0,05mg/kg; Drug: Naloxone 10mg Sponsor: Institut National de la Santé Et de la Recherche Médicale, France Completed Fri, 17 Oct 2014 12:00:00 EDT A Within Subject Comparison of Opioid Withdrawal in Opioid Dependent IndividualsConditions: Opioid Abuse; Opioid DependenceInterventions: Drug: buprenorphine; Drug: morphine Sponsors: Johns Hopkins University; National Institute on Drug Abuse (NIDA) Completed Thu, 03 Jun 2010 12:00:00 EDT Multimodal Analgesic Treatment Versus Traditional Morphine Analgesia After Cardiac SurgeryConditions: Analgesia; Postoperative PainInterventions: Drug: Ibuprofen; Drug: Gabapentin; Drug: Morphine; Drug: Paracetamol Sponsor: Rigshospitalet, Denmark Completed Mon, 21 Oct 2013 12:00:00 EDT Comparison of the Efficacy and Safety of NALDEBAIN With Conventional Treatment After Laparoscopic CholecystectomyCondition: Pain, PostoperativeInterventions: Drug: Naldebain; Drug: Morphine Sponsor: Cathay General Hospital Completed Fri, 19 Oct 2018 12:00:00 EDT
Standard Pain Control or Intrathecal Therapy in Controlling Pain in Patients With Locally Advanced, Unresectable, or Metastatic Pancreatic CancerConditions: Pain; Pancreatic CancerInterventions: Drug: morphine sulfate; Device: Medtronic intrathecal pump Sponsors: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins; National Cancer Institute (NCI) Terminated Thu, 17 Apr 2008 12:00:00 EDT Patients-Controlled Epidural Analgesia After Gastric Bypass for Morbid Obesity Using Morphine-Levobupivacaine RegimensConditions: Morbid Obesity; Postoperative Pain; Postoperative Bowel Function; Postoperative AmbulationInterventions: Drug: GROUP A : 0 mg MORPHINE-0.1% LEVOBUPIVACAINE; Drug: GROUP B : 1 mg MORPHINE- 0.1% LEVOBUPIVACAINE; Drug: GROUP C : 2 mg MORPHINE-0.1% LEVOBUPIVACAINE; Drug: GROUP D : 0 mg MORPHINE- 0.2% LEVOBUPIVACAINE; Drug: GROUP E : 1 mg MORPHINE-0.2 % LEVOBUPIVACAINE; Drug: GROUP F : 2 mg MORPHINE- 0.2% LEVOBUPIVACAINE Sponsor: University of Patras Completed Tue, 30 Nov 2010 12:00:00 EST Effect of Bilateral Quadratus Lumborum Block for Pain Relief in Patients With Cesarean SectionConditions: Caesarean Section; Spinal Anesthesia; Quadratus Lumborum Block; AnalgesiaInterventions: Drug: Intrathecal morphine; Drug: Bilateral Quadratus Lumborum Block; Drug: Intrathecal morphine with bilateral Quadratus Lumborum Block Sponsor: Mahidol University Completed Mon, 26 Jun 2017 12:00:00 EDT Improving Outcomes in Neonatal Abstinence SyndromeConditions: Neonatal Abstinence Syndrome; Neonatal Opioid WithdrawalInterventions: Drug: Neonatal Morphine Solution; Drug: Methadone; Drug: Phenobarbital Sponsor: Tufts Medical Center Completed Wed, 09 Oct 2013 12:00:00 EDT Immediate-Release Oxycodone Capsules Study in Cancer PainCondition: CancerInterventions: Drug: Oxycodone; Drug: Morphine Sponsor: Mundipharma (China) Pharmaceutical Co. Ltd Completed Thu, 30 Aug 2012 12:00:00 EDT Efficacy of Buprenorphine for Treatment of Acute PainCondition: Acute PainInterventions: Drug: Buprenorphine; Drug: Morphine Sponsor: Tehran University of Medical Sciences Completed Thu, 17 Feb 2011 12:00:00 EST Adult Patients Undergoing Open Colectomy MA402S23B303Condition: Bowel ObstructionInterventions: Drug: IV morphine sulfate; Drug: EXPAREL (bupivacaine liposome injectable suspension) Sponsors: Pacira Pharmaceuticals, Inc; Registrat-Mapi Completed Tue, 10 Jan 2012 12:00:00 EST Methadone in Cystectomy PatientsConditions: Pain, Postoperative; Postoperative Complications; Pathologic Processes; Bladder Cancer; Pain; Signs and Symptoms; Neurologic Manifestations; Neurologic Symptoms; Side Effect of DrugInterventions: Drug: Methadone; Drug: Morphine Sponsor: University of Aarhus Recruiting Fri, 17 Jul 2020 12:00:00 EDT Intranasal Ketamine for Acute Traumatic PainCondition: Acute PainInterventions: Drug: Ketamine Hydrochloride; Drug: Morphine Sponsor: Tel Aviv Medical Center Completed Wed, 29 Jun 2016 12:00:00 EDT Incidence of Postoperative Delirium in Cancer Patients After Laparoscopic Surgery in Trendelenburg PositionConditions: Delirium; AnesthesiaInterventions: Procedure: Subarachnoid block; Procedure: Spinal morphine Sponsor: AC Camargo Cancer Center Completed Thu, 28 Jun 2018 12:00:00 EDT
Efficacy of Convulsive Therapies for Bipolar DepressionConditions: Bipolar Disorder; Bipolar Depression; Bipolar I Disorder; Bipolar II DisorderInterventions: Device: Magnetic Seizure Therapy (MST); Device: Electroconvulsive Therapy (ECT) Sponsors: Centre for Addiction and Mental Health; University of British Columbia; Ontario Shores Centre for Mental Health Sciences; Brain Canada Recruiting Wed, 22 Aug 2018 12:00:00 EDT A Relation of Morphine-induced Itch and Pain ProcessingConditions: Morphine; ItchInterventions: Drug: Morphine; Drug: Placebo oral tablet; Drug: Histamine; Drug: Cowhage (Mucuna Pruriens); Drug: isotonic saline Sponsor: Aalborg University Completed Fri, 04 Oct 2019 12:00:00 EDT Electroacupuncture for Laparoscopic/ Robotic Colorectal SurgeryCondition: Acute PainInterventions: Device: electroacupuncture; Drug: morphine Sponsor: The University of Hong Kong Terminated Mon, 16 May 2016 12:00:00 EDT Palliation of Dyspnea in Advanced Chronic Obstructive Pulmonary Disease (COPD)Condition: Chronic Obstructive Pulmonary Disease (COPD)Intervention: Drug: Opioid (morphine sulphate) in low dose Sponsors: Nova Scotia Health Authority; Canadian Institutes of Health Research (CIHR); Nova Scotia Health Research Foundation; Atlantic Health Sciences Corporation Completed Wed, 23 Sep 2009 12:00:00 EDT The Optimization of Procedural Pain Control in Intensive Care Unit (ICU) PatientsCondition: Critical IllnessIntervention: Drug: morphine Sponsors: St. Antonius Hospital; Erasmus Medical Center Completed Wed, 14 Nov 2007 12:00:00 EST SEQ Block for Perioperative Analgesia in Acetabular SurgeryConditions: Anesthesia, Local; Nerve Pain; Pain, Postoperative; Acetabular FractureInterventions: Procedure: Single puncture combined lumbar erector spinae plane block and quadrates lumborum block; Drug: Morphine Sulfate Sponsor: Alexandria University Not yet recruiting Wed, 30 Dec 2020 12:00:00 EST RCT Comparing Analgesia Post-VATS With Epimorph VS PlaceboConditions: Thoracic Surgery, Video-assisted; Postoperative Pain; Rachianesthesia; Sufentanil; MorphineInterventions: Drug: Intrathecal Morphine/Sufentanil; Device: PCA Sponsor: Université de Sherbrooke Terminated Mon, 02 Jun 2014 12:00:00 EDT MORphine Use in the Fascia Iliaca Compartment Block With UltraSoundConditions: Humans; Anesthetics, Local; Morphine; Pain Management; Analgesia; Pain; Anesthesia, Local; Fascia; Emergency Medicine; Analgesia, Patient-Controlled; Ultrasonography; Femoral FractureInterventions: Drug: Levobupivacaine; Drug: Placebo; Drug: Acetaminophen; Drug: Morphine; Procedure: Fascia Iliaca Compartment Block with Levobupivacaine; Procedure: Fascia Iliaca Compartment Block with placebo Sponsors: Zuyderland Medisch Centrum; Fresenius Kabi Terminated Tue, 19 Feb 2019 12:00:00 EST NAS Treatment - Opiate Versus Non-OpiateCondition: Neonatal Abstinence SyndromeInterventions: Drug: Morphine; Drug: Clonidine Sponsor: Henrietta Bada Completed Tue, 27 Nov 2012 12:00:00 EST Ropivacaine Continuous Wound Infusion Versus Intrathecal Morphine for Postoperative Analgesia After Cesarean DeliveryCondition: Obstetric PainInterventions: Device: wound infusion (Dosi-Pain® Kit, LEVENTON SAU, Spain); Procedure: Spinal Anesthesia; Drug: intrathecal morphine; Drug: Ropivacaine (Ropivacaina Molteni®); Drug: Normal saline Sponsors: Saint-Joseph University; LEVENTON Completed Thu, 19 Apr 2018 12:00:00 EDT
Inhaled Morphine Compared With Morphine By Mouth in Treating Cancer Patients With Breakthrough PainConditions: Pain; Unspecified Adult Solid Tumor, Protocol SpecificInterventions: Drug: morphine sulfate; Procedure: quality-of-life assessment Sponsor: Dana-Farber Cancer Institute Completed Fri, 27 Feb 2004 12:00:00 EST Study Comparing a Nerve Block With Spinal Opiate to Provide Pain Relief for Hip Replacement SurgeryCondition: AnalgesiaInterventions: Procedure: ultrasound guided fascia iliaca block; Procedure: spinal morphine Sponsors: Rachel Kearns; NHS Greater Glasgow and Clyde Completed Fri, 08 Oct 2010 12:00:00 EDT Influence of Opioid Analgesia on Circulating Tumor Cells in Laparoscopic Colorectal Cancer SurgeryConditions: Colorectal Cancer; Circulating Tumor CellInterventions: Drug: Morphine; Drug: Piritramid Sponsors: The Institute of Molecular and Translational Medicine, Czech Republic; General University Hospital, Prague; Tomas Bata Hospital, Czech Republic; University Hospital Ostrava; Hospital Novy Jicin Recruiting Tue, 09 Oct 2018 12:00:00 EDT Ultrasound Guided Anterior Quadratus Lumborum BlockConditions: Postoperative Pain; UltrasoundInterventions: Drug: Morphine Sulfate; Procedure: Group P; Procedure: Group A Sponsor: Bursa Yüksek İhtisas Education and Research Hospital Completed Wed, 07 Feb 2018 12:00:00 EST Drug Drug Interactions of Aspirin and P2Y12-inhibitorsConditions: Drug Interaction Potentiation; Myocardial InfarctionInterventions: Drug: Morphine; Drug: Placebo Sponsor: Medical University of Vienna Completed Wed, 08 Jun 2011 12:00:00 EDT Multimodal Analgesia With Interfascial Continuous Wound Infiltration: A Randomized Clinical TrialCondition: PainInterventions: Device: 19Gx500-mm Pajunk InfiltraLong® catheter; Drug: morphine Sponsor: Hospital Galdakao-Usansolo Completed Fri, 22 Aug 2014 12:00:00 EDT Ketorolac for Moderate to Severe Abdominal Pain in ChildrenConditions: Abdominal Pain; Appendicitis; Analgesia; Child, Only; EmergenciesInterventions: Drug: Ketorolac Tromethamine 10 MG/ML; Drug: Morphine Sulfate 10Mg/1mL Injection Sponsor: Hamilton Health Sciences Corporation Recruiting Thu, 27 Aug 2020 12:00:00 EDT A Comparison of the Safety and Effectiveness of Two Forms of Patient-controlled Pain Medication Used After Scheduled Abdominal or Pelvic Surgery: The Fentanyl Transdermal System Versus the Morphine Intravenous PumpCondition: Pain, PostoperativeIntervention: Drug: E-TRANS Fentanyl hydrochloride; Morphine Sponsors: Alza Corporation, DE, USA; PriCara, Unit of Ortho-McNeil, Inc. Completed Mon, 19 Dec 2005 12:00:00 EST A Comparison of the Safety and Effectiveness of Two Forms of Patient-controlled Pain Medication Used After Total Hip Replacement: The E-TRANS Fentanyl Transdermal System Versus the Morphine Intravenous PumpConditions: Pain, Postoperative; AnalgesiaIntervention: Drug: E-TRANS Fentanyl hydrochloride; Morphine Sponsors: Alza Corporation, DE, USA; PriCara, Unit of Ortho-McNeil, Inc. Completed Tue, 13 Dec 2005 12:00:00 EST Individualized Analgesia for Pediatric AdenotonsillectomyConditions: Adenotonsillectomy; AnalgesiaInterventions: Drug: Individualized oral morphine; Drug: Conventional oral morphine Sponsor: Children's Hospital of Fudan University Not yet recruiting Wed, 26 Aug 2020 12:00:00 EDT
Morphine After Radiofrequency Ablation of Painful Bone Metastases in Patients With CancerConditions: Metastatic Cancer; Pain; Unspecified Adult Solid Tumor, Protocol SpecificInterventions: Drug: Acetaminophen; Drug: Morphine Sulfate; Other: Questionnaire administration; Procedure: Quality-of-life assessment; Procedure: Radiofrequency ablation Sponsor: Institut Bergonié Completed Thu, 10 Jul 2008 12:00:00 EDT Comparing the Outcome of Two Intraoperative Analgesia Techniques After Hepato-pancreato-biliary SurgeryConditions: Pain; Analgesia; SedationInterventions: Drug: Intrathecal morphine; Drug: Continuous IV remifentanil Sponsor: Tel-Aviv Sourasky Medical Center Unknown status Tue, 14 Sep 2010 12:00:00 EDT Methadone, Morphine, or Oxycodone in Treating Pain in Patients With CancerConditions: Brain and Central Nervous System Tumors; Chronic Myeloproliferative Disorders; Leukemia; Lymphoma; Lymphoproliferative Disorder; Multiple Myeloma and Plasma Cell Neoplasm; Myelodysplastic Syndromes; Myelodysplastic/Myeloproliferative Neoplasms; Pain; Precancerous Condition; Unspecified Adult Solid Tumor, Protocol SpecificInterventions: Drug: methadone hydrochloride; Drug: morphine sulfate; Drug: oxycodone hydrochloride Sponsors: M.D. Anderson Cancer Center; National Cancer Institute (NCI) Terminated Fri, 01 Aug 2008 12:00:00 EDT A Comparative Study With Parenteral Oxycodone, Morphine and Dexamethasone in Postoperative Pain in Paediatric PatientsCondition: Post Tonsillectomy PainInterventions: Drug: 0,1 mg/kg of oxycodone; Drug: Morphine 0,1 mg/kg; Drug: Dexamethasone 0,5 mg/kg; Drug: NaCl 0,9% Sponsor: University of Turku Unknown status Tue, 12 Aug 2008 12:00:00 EDT A Safety and Efficacy Study of Oral Tapentadol Extended-Release in Japanese ParticipantsCondition: NeoplasmsInterventions: Drug: Tapentadol ER; Drug: Morphine SR Sponsor: Janssen Pharmaceutical K.K. Completed Mon, 07 Mar 2011 12:00:00 EST Ketamine Improves Post-Thoracotomy AnalgesiaCondition: Post Operative PainInterventions: Drug: morphine; Drug: morphine ketamine Sponsor: Tel-Aviv Sourasky Medical Center Completed Fri, 29 Feb 2008 12:00:00 EST Inhaled vs IV Opioid Dosing for the Initial Treatment of Severe Acute Pain in the Emergency DepartmentConditions: Pain, Acute; Emergencies; MorphineInterventions: Drug: inhaled titration of morphine chlorhydrate; Drug: IV placebo; Device: Inhaled placebo; Drug: IV titration of morphine chlorhydrate Sponsor: University Hospital, Rouen Unknown status Tue, 22 Aug 2017 12:00:00 EDT Hormone Function in Men Treated for Pain With Opioids or PlaceboConditions: Chronic Pain; OsteoarthritisInterventions: Drug: MS Contin; Drug: Placebo Sponsor: National Institute of Nursing Research (NINR) Completed Wed, 20 Aug 2008 12:00:00 EDT Oxycodone Hydrochloride Injection in the Postoperative Pain Relieving TreatmentCondition: Other Acute Postoperative PainInterventions: Drug: Oxycodone; Drug: Morphine Sponsor: Mundipharma (China) Pharmaceutical Co. Ltd Completed Fri, 25 Feb 2011 12:00:00 EST Cyclizine Vs. Dexamethasone for Nausea and Vomiting Following Intrathecal Morphine in Cases of Cesarean SectionCondition: Spinal Anesthetics Causing Adverse Effects in Therapeutic UseIntervention: Drug: IV Cyclizine versus IV Dexamethasone for prevention of nausea and vomiting after intrathecal morphine in patients undergoing cesarean section Sponsor: Assiut University Unknown status Tue, 30 Apr 2019 12:00:00 EDT
Analgesic Efficacy of Transmucosal Fentanyl for Breakthrough Pain Caused by Interventional GastrostomyConditions: Gastrostomy; Breakthrough Pain; Upper Aerodigestive Tract NeoplasmsInterventions: Drug: Fentanyl; Drug: Morphine Sulfate; Drug: Fentanyl placebo; Drug: Morphine Sulfate placebo; Procedure: Gastrostomy Sponsor: Central Hospital, Nancy, France Completed Tue, 16 Aug 2016 12:00:00 EDT Psychological Intervention and Physiotherapy With Medication Improves CRPS Patients OutcomeCondition: CRPSInterventions: Drug: Morphine, memantine; Behavioral: Psychological intervention; Other: Physiotherapy intervention Sponsor: Helsinki University Central Hospital Completed Wed, 10 Jun 2015 12:00:00 EDT Pharmacokinetics and Pharmacodynamics of TRV130, Morphine, and Placebo in Healthy SubjectsCondition: Pain, AcuteInterventions: Drug: TRV130 1.5 mg; Drug: TRV130 3 mg; Drug: TRV130 4.5 mg; Drug: Morphine 10 mg; Drug: Placebo Sponsor: Trevena Inc. Completed Tue, 11 Mar 2014 12:00:00 EDT IV Paracetamol, Dexketoprofen or Morphine for the Treatment of Low Back PainCondition: Low Back PainInterventions: Drug: paracetamol; Drug: morphine; Drug: Dexketoprofen; Drug: Paracetamole Sponsor: Pamukkale University Completed Tue, 23 Aug 2011 12:00:00 EDT Naloxone for the Treatment of Opioid-Induced PruritusCondition: PruritusInterventions: Drug: Naloxone; Drug: Saline/Morphine Sponsor: University of British Columbia Completed Thu, 18 Feb 2010 12:00:00 EST Analgesic and Antihyperalgesic Effects of Morphine and BuprenorphineCondition: PainInterventions: Drug: morphine LO; Drug: Morphine Hi; Drug: Buprenorphine LO; Drug: Buprenorphine Hi; Other: saline Sponsors: mads u werner; Norpharma A/S Completed Tue, 15 Feb 2011 12:00:00 EST Evaluation of MST-188 in Acute Lower Limb IschemiaCondition: Acute Limb IschemiaInterventions: Drug: MST-188; Drug: Saline Sponsor: Mast Therapeutics, Inc. Terminated Fri, 21 Mar 2014 12:00:00 EDT Drug Interactions Between Morphine and Orally or IV Administered AcetaminophenCondition: PainInterventions: Drug: Oral Acetaminophen; Drug: IV Acetaminophen; Drug: IV Morphine; Drug: Placebo Tablets; Drug: Saline Sponsor: Mallinckrodt Completed Thu, 28 Jul 2016 12:00:00 EDT Intravenous vs Oral Analgesia in Cancer Patients With Severe Pain After Successful TitrationCondition: Cancer PainInterventions: Drug: PCA IV Hydromorphone (continuous dose = 0); Drug: PCA IV Hydromorphone (continuous dose ≠ 0); Drug: Oral morphine Sponsor: Fujian Cancer Hospital Completed Tue, 28 Jan 2020 12:00:00 EST Femoral Neuropathy After Anterior Cruciate Ligament Reconstruction: Femoral Nerve Block vs Patient-controlled Analgesia (PCA)Condition: Femoral NeuropathyInterventions: Procedure: Femoral nerve block; Procedure: PCA morphine Sponsor: Centre Hospitalier Universitaire Vaudois Completed Wed, 23 Mar 2011 12:00:00 EDT
Opiate-Induced Tolerance & Hyperalgesia in Pain PatientsConditions: Chronic Low Back Pain; Opioid-induced HyperalgesiaInterventions: Drug: Morphine; Drug: Placebo Sponsor: National Institute of General Medical Sciences (NIGMS) Completed Sun, 30 Oct 2005 12:00:00 EDT Magnetic Seizure Therapy (MST) for Treatment Resistant Major DepressionCondition: Major DepressionInterventions: Device: Thymatron; Device: Tonica MagPro MST Sponsor: University Hospital, Bonn Completed Fri, 10 Oct 2008 12:00:00 EDT Adductor Canal Block Versus Patient Controlled Analgesia, in the Surgical Stress Response for Anterior Cruciate Ligament RepairConditions: Anesthesia; Stress, Physiological; SurgeryInterventions: Procedure: Adductor Canal Block; Device: Morphine Patient Controlled Analgesia Sponsor: Pontificia Universidad Catolica de Chile Withdrawn Mon, 15 Mar 2021 12:00:00 EDT The Analgesic Efficacy of Periarticular Infiltration of Local Anaesthetic for Total Hip ReplacementCondition: Total Hip ArthroplastyInterventions: Drug: Levobupivacaine; Drug: Intrathecal morphine Sponsor: Cork University Hospital Unknown status Thu, 10 Mar 2011 12:00:00 EST Preemptive Analgesia With Morphine Sulphate in Major Urological SurgeryCondition: PainIntervention: Sponsor: University of Roma La Sapienza Unknown status Wed, 22 Jan 2014 12:00:00 EST Choosing Opioid Management for Pain and Analyzing Acute Chest Syndrome (ACS) Rates EquallyConditions: Pain; Sickle Cell DiseaseInterventions: Drug: Morphine; Drug: Nubain Sponsors: Children's Healthcare of Atlanta; Atlanta Clinical and Translational Science Institute Completed Mon, 27 Jun 2011 12:00:00 EDT Buprenorphine in Acute Renal Colic Pain ManagementConditions: Acute Pain Management; Renal ColicInterventions: Drug: Buprenorphine; Drug: Morphine Sponsor: Tehran University of Medical Sciences Completed Wed, 07 Mar 2012 12:00:00 EST Interest of the Injection of Morphine, in Addition to a Local Anesthetic When Performing a Combined Spinal-epidural for Labor AnalgesiaCondition: Pregnant WomenInterventions: Drug: experimental group : sequential combined spinal epidural with local anesthetic injection (chirocaine) associated with morphine (sufentanil).; Drug: control group : sequential combined spinal epidural with local anesthetic injection (chirocaine) alone. Sponsor: CHU de Reims Completed Tue, 16 Aug 2016 12:00:00 EDT To Compare the Efficacy and Patients' Satisfaction for the Treatment of Post Cesarean Pain of Two Protocols: Oral Medications in Fixed Time Interval Administration Versus Spinal MorphineCondition: Post Cesarean Pain ManagementInterventions: Drug: Tramadol hydrochloride; Drug: Morphine; Drug: Paracetamol; Drug: Diclofenac; Drug: TAB. Percocet (Oxycodone 5MG/Paracetamol 325 MG) Sponsor: HaEmek Medical Center, Israel Completed Tue, 12 May 2015 12:00:00 EDT A Study of TRV130 for the Treatment of Pain After BunionectomyCondition: Acute PainInterventions: Drug: TRV130; Drug: Morphine; Drug: Placebo Sponsor: Trevena Inc. Completed Tue, 01 Apr 2014 12:00:00 EDT
Clinical Effectiveness and Safety of Intraoperative Methadone in Patients Undergoing Laparoscopic HysterectomyCondition: Postoperative PainInterventions: Drug: Methadone; Drug: Morphine Sponsor: University of Aarhus Recruiting Tue, 09 Apr 2019 12:00:00 EDT Ultrasound Guided Femoral Nerve BlockCondition: Hip FractureInterventions: Other: ultra-sound guide; Drug: bupivacaine; Drug: morphine Sponsor: Beth Israel Deaconess Medical Center Recruiting Fri, 06 Mar 2015 12:00:00 EST Confirmatory Efficacy and Safety Trial of Magnetic Seizure Therapy for DepressionConditions: Depression; Unipolar Depression; Treatment Resistant DepressionInterventions: Device: Magnetic Seizure Therapy; Device: Electroconvulsive Therapy Sponsors: University of Texas Southwestern Medical Center; National Institute of Mental Health (NIMH); Centre for Addiction and Mental Health Recruiting Mon, 19 Jun 2017 12:00:00 EDT Oral Self Medication Versus IV Administration of Pain Killers After Caesarian DeliveryCondition: Caesarian SectionInterventions: Drug: Acetaminophen, ketoprofen, morphine; Drug: Acetaminophen, ketoprofen,morphine Sponsors: University Hospital, Montpellier; Club anesthésie Reanimation Obstetricale Completed Thu, 29 Mar 2012 12:00:00 EDT Platelet Inhibition After Pre-hospital Ticagrelor Using Fentanyl Compared to Morphine in Patients With ST-segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary InterventionCondition: Acute Myocardial InfarctionInterventions: Drug: Fentanyl; Drug: Morphine; Drug: Ticagrelor; Drug: Aspirin; Drug: Unfractioned Heparin; Procedure: Primary PCI Sponsors: Centre Hospitalier Universitaire Vaudois; AstraZeneca Completed Mon, 24 Aug 2015 12:00:00 EDT Study of Morphine in Postoperative Infants to Allow Normal VentilationConditions: Infant, Newborn, Diseases; PainIntervention: Drug: morphine Sponsor: Seattle Children's Hospital Completed Fri, 25 Feb 2000 12:00:00 EST Evaluation of the Benefit of Non-opioid General Anaesthesia on Postoperative Pain in Laparoscopic Colonic SurgeryCondition: ColectomyInterventions: Drug: anaesthesia without opiates; Drug: anaesthesia with morphine Sponsor: GCS Ramsay Santé pour l'Enseignement et la Recherche Recruiting Wed, 01 Sep 2021 12:00:00 EDT Prospective Effect of Intravenous Ketorolac on Opioid Use and Complications Following Cesarean DeliveryCondition: Analgesia, ObstetricalInterventions: Drug: Ketorolac; Drug: Epidural Morphine; Drug: Hydromorphone Sponsor: University Hospitals Cleveland Medical Center Unknown status Tue, 28 Jul 2015 12:00:00 EDT Impact of Dexamethasone Added to Intra-articular Morphine and Bupivacaine for Post-operative Analgesia After Knee ArthroscopyCondition: AnesthesiaInterventions: Drug: group M; Drug: group MD Sponsor: Ain Shams University Completed Wed, 10 Mar 2021 12:00:00 EST Erector Spinae Plane Block Catheters and Intrathecal Morphine for Hepatic ResectionConditions: Hepatic Resection; Acute Pain; Anesthesia; Anesthesia, LocalInterventions: Drug: 0.2% ropivacaine local anesthetic continuous erector spinae plane block; Drug: 0.2% ropivacaine local anesthetic superficially taped continuous erector spinae plane block; Drug: Spinal Morphine Sponsor: University of California, San Diego Recruiting Mon, 19 Apr 2021 12:00:00 EDT
Morphine Postoperative Analgesia and Pharmacokinetic/Pharmacodynamic ModelingCondition: Cardiopulmonar Artery Bypass GraftingIntervention: Sponsors: University of Sao Paulo; Fundação de Amparo à Pesquisa do Estado de São Paulo; Conselho Nacional de Desenvolvimento Científico e Tecnológico Completed Tue, 27 Mar 2012 12:00:00 EDT Dexmedetomidine Supplemented Analgesia and Long-term Survival After Cancer SurgeryConditions: Elderly; Surgery; Analgesia; Dexmedetomidine; Long-term OutcomeInterventions: Drug: Dexmedetomidine supplemented morphine analgesia; Drug: Morphine analgesia Sponsors: Peking University First Hospital; Affiliated Hospital of Hebei University; Qingdao Municipal Hospital; The Second Affiliated Hospital of Air Force Medical University; Beijing Chao Yang Hospital; Beijing Shijitan Hospital, Capital Medical University; Beijing Tsinghua Chang Gung Hospital; Peking University International Hospital; Beijing Ditan Hospital; Guizhou Provincial People's Hospital; The Third Xiangya Hospital of Central South University; Shanxi Provincial Cancer Hospital; Tianjin Hospital of ITCWM-Nankai Hospital; Zhongda Hospital Southeast University Recruiting Fri, 06 Jan 2017 12:00:00 EST Dexmedetomidine Supplemented Analgesia and Incidence of Postoperative DeliriumConditions: Elderly; Surgery; Analgesia; Dexmedetomidine; Complication, Postoperative; DeliriumInterventions: Drug: Dexmedetomidine supplemented morphine analgesia; Drug: Morphine analgesia Sponsors: Peking University First Hospital; Affiliated Hospital of Hebei University; Qingdao Municipal Hospital; The Second Affiliated Hospital of Air Force Medical University; Beijing Chao Yang Hospital; Beijing Shijitan Hospital, Capital Medical University; Beijing Tsinghua Chang Gung Hospital; Peking University International Hospital; Beijing Ditan Hospital; Guizhou Provincial People's Hospital; The Third Xiangya Hospital of Central South University; Shanxi Provincial Cancer Hospital; Tianjin Hospital of ITCWM-Nankai Hospital; Zhongda Hospital Southeast University Recruiting Fri, 06 Jan 2017 12:00:00 EST Efficacy Methadone for Management Postoperative Pain After the Use of Anesthesia Intravenous in Laparoscopic CholecystectomyCondition: Pain, PostoperativeInterventions: Drug: Morphine; Drug: Methadone; Drug: TIVA Sponsor: Universidad de Valparaiso Completed Wed, 17 Apr 2013 12:00:00 EDT Breathlessness Exertion and Morphine SulphateConditions: Chronic Obstructive Pulmonary Disease; DyspneaInterventions: Drug: Placebo; Drug: Morphine Sulfate; Drug: Plus laxative (Docusate with senna); Drug: Plus placebo laxative; Device: FitBit charge HR (Accelerometer) Sponsor: Flinders University Completed Mon, 28 Mar 2016 12:00:00 EDT Pain Relief of Metoprolol Versus Metoprolol Plus Morphine in Acute Chest PainCondition: Acute Coronary SyndromesInterventions: Drug: Metoprolol; Drug: metoprolol plus morphine Sponsors: Sahlgrenska University Hospital, Sweden; AstraZeneca Completed Fri, 18 Jul 2008 12:00:00 EDT High Pain Intervention in Cesarean SectionsCondition: Other Chronic Postoperative PainInterventions: Drug: Duramorph 150; Drug: Acetaminophen; Drug: Duramorph 300 Sponsor: Wake Forest University Health Sciences Completed Fri, 18 Feb 2011 12:00:00 EST Evaluation of the Safety and Efficacy of EXPAREL When Administered Into the TAP in Subjects Undergoing Cesarean SectionCondition: PainInterventions: Drug: Intrathecal morphine injection; Drug: EXPAREL Sponsor: Pacira Pharmaceuticals, Inc Terminated Tue, 03 Feb 2015 12:00:00 EST Efficacy of Nefopam and Morphine in Balanced Analgesia for Acute Ureteric ColicCondition: Renal ColicInterventions: Drug: Ketorolac and nefopam balanced analgesia; Drug: Balanced analgesia using ketorolac and morphine; Drug: Pain control with single analgesics (ketorolac) Sponsors: Seoul National University Hospital; Pharmbio Korea Unknown status Fri, 02 Mar 2012 12:00:00 EST Sub-dissociative Ketamine for the Management of Acute Pediatric PainCondition: PainInterventions: Drug: Ketamine; Drug: Morphine Sponsor: HealthPartners Institute Completed Fri, 27 Sep 2013 12:00:00 EDT
Bunionectomy Trial With GRT6005Condition: Post Operative PainInterventions: Drug: GRT6005; Drug: Morphine; Drug: Placebo Sponsor: Tris Pharma, Inc. Completed Tue, 31 Mar 2009 12:00:00 EDT Comparative Effectiveness Clinical Trial of MST Compared to ECT in Major Depressive DisorderCondition: Major Depressive DisorderInterventions: Device: Electroconvulsive Therapy (n=30); Device: Magnetic Seizure Therapy (n=30) Sponsors: Tanta University; Nagy A. Youssef (Consultant on the MST technique) Completed Thu, 02 Jan 2020 12:00:00 EST Reduction in Pain Intensity Following IV or Oral Pain-relieving ProductsCondition: PainInterventions: Drug: IV Acetaminophen (Treatment A); Drug: Oral Acetaminophen (Treatment B); Drug: Placebo (Treatment C); Other: Morphine (Treatment D) Sponsor: Mallinckrodt Completed Tue, 09 Feb 2016 12:00:00 EST A Study of TRV130 for the Treatment of Pain After AbdominoplastyCondition: PainInterventions: Drug: TRV130; Drug: Morphine; Drug: Placebo Sponsors: Trevena Inc.; Lotus Clinical Research, LLC Completed Fri, 09 Jan 2015 12:00:00 EST Oral Analgesic Utilization for CHildhood Musculoskeletal InjuriesCondition: Musculoskeletal InjuryInterventions: Drug: oral morphine and oral ibuprofen; Drug: Oral morphine; Drug: Oral ibuprofen Sponsor: St. Justine's Hospital Completed Mon, 17 Feb 2014 12:00:00 EST Methadone in Neuropathic PainCondition: Chronic Neuropathic PainInterventions: Drug: Methadone; Drug: Controlled Release Morphine Sponsors: Nova Scotia Health Authority; Canadian Institutes of Health Research (CIHR); Nova Scotia Health Research Foundation; Dalhousie University Terminated Mon, 20 Sep 2010 12:00:00 EDT Non-opioid Analgesic Combination With Morphine for Postoperative Analgesia.Condition: Post Operative AnalgesiaInterventions: Drug: Paracetamol; Drug: Nefopam; Drug: Ketoprofen; Drug: Morphine Sponsor: Rennes University Hospital Terminated Thu, 20 Jun 2013 12:00:00 EDT Genetic Effects on Dopamine Response to an OpiateConditions: Polymorphism-Genetic; Pain; AddictionInterventions: Drug: Morphine; Drug: Placebo Sponsors: National Institute on Alcohol Abuse and Alcoholism (NIAAA); National Institute on Drug Abuse (NIDA) Completed Fri, 14 Jun 2013 12:00:00 EDT Perioperative Pain Management In Spine Surgery Patients: Part ICondition: PainInterventions: Drug: 150% Oral Morphine Equivalent (OME); Other: Clinical Judgment Sponsor: Allina Health System Completed Thu, 06 Oct 2011 12:00:00 EDT CHF6563 in Babies With Neonatal Opioid Withdrawal SyndromeCondition: Neonatal Opioid Withdrawal SyndromeInterventions: Drug: CHF6563; Drug: Morphine; Drug: CHF6563 matched placebo; Drug: Morphine matched placebo Sponsor: Chiesi Farmaceutici S.p.A. Recruiting Thu, 26 Sep 2019 12:00:00 EDT
Premedication and Haemodynamics After Spinal AnesthesiaCondition: Hemodynamics After Spinal AnesthesiaInterventions: Drug: Morphine hydrochloride; Midazolam; Drug: Midazolam Sponsor: Medical University of Gdansk Completed Wed, 10 Feb 2010 12:00:00 EST Methadone for Spinal Fusion Surgery.Conditions: Pain, Postoperative; Back Pain; Opioid Use; Methadone; Degenerative Spondylolisthesis; Stenosis, SpinalInterventions: Drug: Methadone; Drug: Morphine Sponsor: Aarhus University Hospital Recruiting Sun, 21 Feb 2021 12:00:00 EST Low Dose Extended-release Epidural and Lumbar Plexus Block Compared to Lumbar Plexus Block for Total Hip ResurfacingCondition: Hip ArthroplastyInterventions: Drug: Extended Release Epidural Morphine (EREM); Drug: Placebo Sponsors: Wake Forest University; EKR Therapeutics, Inc Terminated Wed, 08 Jul 2009 12:00:00 EDT Opioid Treatment for Chronic Low Back Pain and the Impact of Mood SymptomsConditions: Chronic Low Back Pain; Degenerative Disc Disease; Depression; AnxietyInterventions: Drug: Oxycodone; Drug: Morphine; Drug: Placebo Sponsors: Brigham and Women's Hospital; Arthritis Foundation; National Institute on Drug Abuse (NIDA) Completed Mon, 02 Jan 2012 12:00:00 EST The Effects of Scalp Block on Haemodynamic Response and Postoperative Pain in Posterior Fossa SurgeryCondition: Posterior Fossa TumorsInterventions: Drug: Bupivacaine; Drug: morphine patient controlled analgesia Sponsor: Istanbul University Completed Tue, 02 Aug 2016 12:00:00 EDT A Study of Serial Magnetic Resonance Cholangiopancreatography (MRCP) Following Morphine-neostigmine and Secretin Provocation in Healthy VolunteersCondition: Sphincter of Oddi DysfunctionInterventions: Drug: Morphine; Drug: Neostigmine; Drug: 0.9% saline; Drug: Secretin Sponsor: University of Nottingham Completed Wed, 02 Jun 2010 12:00:00 EDT Effect of Pain Control on the Diagnosis of Acute Appendicitis on the Diagnostic Accuracy of General SurgeonCondition: AppendicitisIntervention: Drug: Morphine Sponsor: Seoul National University Hospital Completed Fri, 31 Oct 2008 12:00:00 EDT Effects of Different Types of Perioperative Analgesia on Minimal Residual Disease Development After Colon Cancer SurgeryConditions: Colon Cancer; Minimal Residual DiseaseInterventions: Other: Epidural analgesia; Drug: Piritramide; Drug: Morphine Sponsors: The Institute of Molecular and Translational Medicine, Czech Republic; Brno University Hospital; Tomas Bata Hospital, Czech Republic Completed Thu, 11 Dec 2014 12:00:00 EST Brain Effects of Opiate Agonist and AntagonistCondition: Chronic Low-back PainIntervention: Drug: Morphine Sponsor: University of Rochester Completed Fri, 10 Apr 2020 12:00:00 EDT A Study of the Safety and Efficacy of Combination Therapy With Morphine, Phenylephrine and Sorbitol in Human SubjectsCondition: Acute PainInterventions: Drug: Morphine; Drug: Sorbitol+Phenylephrine; Drug: Sorbitol+Phenylephrine+Morphine; Drug: Sorbitol low concentration+Phenylephrine+Morphine Sponsor: BioLineRx, Ltd. Completed Tue, 12 Sep 2006 12:00:00 EDT
Efficacy and Safety of EXPAREL Versus Standard of Care (SoC) in Subjects Undergoing Elective Cesarean SectionConditions: Elective Cesarean Section; Pain ManagementInterventions: Drug: 50 mcg Duramorph+ EXPAREL + multi-modal pain regimen; Drug: 150 mcg Duramorph + multi-modal pain regimen; Drug: Exparel TAP + multi-modal pain regimen Sponsor: Pacira Pharmaceuticals, Inc Completed Tue, 26 Feb 2019 12:00:00 EST Study To Assess The Effect Of Gabapentin, Diphenhydramine And Morphine On Cold Pain In Healthy Male VolunteersCondition: HealthyInterventions: Drug: Gabapentin; Drug: Diphenhydramine; Drug: Morphine; Drug: Placebo Sponsor: Pfizer Completed Fri, 07 May 2010 12:00:00 EDT Mindfulness as Treatment of Sexological ProblemsConditions: Sexual Dysfunction; Sexual Dysfunctions, Psychological; Sexual Dysfunctions, PhysiologicalInterventions: Behavioral: Mindfulness in Sex Therapy and Intimate Relationships (MSIR); Behavioral: Treatment-as-usual Sponsors: Mental Health Services in the Capital Region, Denmark; Den Owesenske Fond Active, not recruiting Thu, 13 Dec 2018 12:00:00 EST Efficacy Study of Rectus Sheath Block to Control Postoperative PainCondition: Pain, PostoperativeInterventions: Procedure: ultrasound guided rectus sheath block; Drug: Morphine Sponsor: Cukurova University Completed Tue, 15 Apr 2014 12:00:00 EDT Evaluation of Repeat Administration of Purified Poloxamer 188Condition: Sickle Cell DiseaseIntervention: Drug: MST-188 Sponsor: Mast Therapeutics, Inc. Completed Wed, 20 May 2015 12:00:00 EDT Efficacy Study of Different Analgesic Options in Kidney Stone Pain ManagementConditions: Renal Colic; Urinary CalculiInterventions: Drug: Diclofenac; Drug: Morphine; Drug: Paracetamol; Drug: Placebos Sponsor: Hamad Medical Corporation Completed Fri, 11 Jul 2014 12:00:00 EDT Evaluation of Purified Poloxamer 188 in Vaso-Occlusive Crisis of Sickle Cell Disease (EPIC)Conditions: Vaso-occlusive Crisis; Sickle Cell DiseaseInterventions: Drug: Saline; Drug: MST-188 Sponsor: Mast Therapeutics, Inc. Completed Fri, 30 Nov 2012 12:00:00 EST Cortical Modulation of Acute Post-thoracotomy Pain With Transcranial Direct Current StimulationCondition: Pain, PostoperativeInterventions: Device: Transcranial direct current stimulation; Drug: Morphine Sponsor: Military Medical Academy, Belgrade, Serbia Completed Thu, 29 Dec 2016 12:00:00 EST Transversus Abdominis Plane Block for Laparoscopic HysterectomyConditions: Hysterectomy; Laparoscopic SurgeryInterventions: Other: USguided bilateral TAP block; Drug: Morphine Patient Controlled Analgesia Sponsor: Istituti Ospitalieri di Cremona Completed Tue, 13 Mar 2012 12:00:00 EDT Multicenter Study to Compare Intravenous and Oral Acetaminophen for the Treatment of Acute Moderate to Severe PainCondition: Acute Pain, PostoperativeInterventions: Drug: IV acetaminophen; Drug: Oral acetaminophen; Drug: Morphine Sponsor: Mallinckrodt Terminated Thu, 21 Apr 2016 12:00:00 EDT
Sensorial and Physiological Mechanism-based Assessments of Perioperative PainCondition: ScoliosisInterventions: Drug: Clonidine; Other: Morphine Sponsor: Dr. Jean A. Ouellet, MD, FRCSC Suspended Fri, 25 May 2018 12:00:00 EDT Dexmedetomidine in Pediatric TonsillectomyConditions: Pediatric Adenotonsillectomy; Post Operative AnalgesiaInterventions: Drug: Dexmedetomidine 0.75 mcg/kg; Drug: Morphine 50 mcg/kg; Drug: Morphine 100 mcg/kg; Drug: Dexmedetomidine 1 mcg/kg Sponsor: Baylor College of Medicine Completed Wed, 27 Jan 2010 12:00:00 EST Comparison of the Efficacy and Safety of Q8003 Versus Its Individual Components in Bunionectomy PatientsCondition: Moderate to Severe Postoperative PainInterventions: Drug: Q8003; Drug: Morphine sulfate; Drug: Oxycodone HCl Sponsor: QRxPharma Inc. Completed Fri, 20 Nov 2009 12:00:00 EST Study Comparing Magnetic Seizure Therapy (MST) to Electroconvulsive Therapy (ECT) for Depression in Older AdultsConditions: Depression; Major Depressive Episode; Bipolar DisorderInterventions: Device: MagVenture MagPro MST; Biological: RUL ECT Sponsor: New York State Psychiatric Institute Completed Wed, 05 Jun 2013 12:00:00 EDT Postpartum Perineal Pain After Obstetric Anal Sphincter InjuriesConditions: Pain; Postpartum DepressionInterventions: Drug: Epidural saline + IV saline; Drug: Epidural morphine 3 mg + IV saline; Drug: Epidural morphine 3 mg + IV ketamine 0.3 mg/kg Sponsor: Northwestern University Recruiting Tue, 20 Mar 2018 12:00:00 EDT Safety and Efficacy of Patient Controlled Analgesia in the Emergency DepartmentCondition: PainInterventions: Device: Patient-controlled analgesia; Drug: morphine Sponsors: Albert Einstein College of Medicine; National Institutes of Health (NIH); National Institute of Nursing Research (NINR); Jacobi Medical Center Completed Fri, 29 May 2009 12:00:00 EDT Efficacy of Convulsive Therapies During ContinuationConditions: Depression; Bipolar Depression; Unipolar Depression; Treatment Resistant DepressionInterventions: Device: Magnetic Seizure Therapy (MST); Device: RUL-UB ECT; Device: Bitemporal ECT Sponsors: Centre for Addiction and Mental Health; University of British Columbia; Ontario Shores Centre for Mental Health Sciences; Brain Canada Recruiting Thu, 18 Oct 2018 12:00:00 EDT Pharmacogenomics Analysis of Morphine Pharmacokinetics in Pediatric Tonsillectomy and AdenoidectomyConditions: Tonsillectomy; Adenoidectomy; PharmacokineticsIntervention: Sponsors: Children's Hospital of Philadelphia; Children's Anesthesiology Associates, Ltd. Completed Wed, 04 Feb 2009 12:00:00 EST Gender and Opioid ConsumptionCondition: Postoperative; ParotitisIntervention: Drug: postoperative morphine Sponsor: Mansoura University Unknown status Fri, 30 Dec 2016 12:00:00 EST Effects of Analgesia Methods on Vascular Endothelial Growth Factor* and Inflammatory Responses in Breast Cancer SurgeryCondition: Breast CancerInterventions: Drug: Morphine; Procedure: Erector Spinae Block; Drug: Control Sponsor: Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital Not yet recruiting Wed, 30 Dec 2020 12:00:00 EST
Opioid Effects on Swallowing Comparing Younger and Elderly VolunteersConditions: Pharyngeal Dysfunction; Pharyngeal SwallowingInterventions: Drug: Morphine; Drug: Remifentanil Sponsor: Region Örebro County Completed Fri, 16 Aug 2013 12:00:00 EDT The Influence of Postoperative Analgesia on Systemic Inflammatory Response and POCD After Femoral Fractures SurgeryCondition: Postoperative Cognitive DysfunctionInterventions: Drug: morphine; Drug: levobupivacaine Sponsor: Osijek University Hospital Completed Thu, 28 Jul 2016 12:00:00 EDT Influence of METHoxyflurane on ANtiplatelet Effect of Ticagrelor in Patients With Unstable Angina PectorisCondition: Unstable AnginaInterventions: Drug: Ticagrelor followed with Methoxyflurane; Drug: Ticagrelor followed with Morphine; Drug: Ticagrelor alone Sponsor: Collegium Medicum w Bydgoszczy Recruiting Tue, 23 Jun 2020 12:00:00 EDT A Study to Look at Tapentadol Tablets in Children and Adolescents in PainCondition: PainInterventions: Drug: Tapentadol prolonged release; Drug: Morphine prolonged release Sponsor: Grünenthal GmbH Completed Fri, 30 May 2014 12:00:00 EDT Does IVPCA Increase Opioid Consumption and Side Effects in Fast Track Orthopedic Procedures?Condition: Pain, PostoperativeInterventions: Drug: Morphine as IVPCA; Drug: Hydromorphone as IVPCA; Drug: Morphine; Drug: Hydromorphone Sponsor: Mount Sinai Hospital, Canada Unknown status Fri, 26 Aug 2016 12:00:00 EDT A Randomized Control Trial Comparing Analgesic Benefits of Ultrasound-guided Single vs Continuous Quadratus Lumborum Blocks (QLB)vs Intrathecal Morphine(ITM) for Post Cesarean Section PainCondition: Pain, PostoperativeInterventions: Drug: Intrathecal morphine sulfate (ITM); Drug: Bupivacaine hydrochloride; Drug: ropivacaine hydrochloride Sponsor: The University of Texas Health Science Center, Houston Active, not recruiting Wed, 29 Apr 2020 12:00:00 EDT Inhaled Cannabinoids Versus Immediate-release Oral Opioids for the Management of Breakthrough Cancer PainConditions: Cancer; Breakthrough Cancer PainInterventions: Drug: PPP001; Drug: Morphine sulfate or Hydromorphone or Oxycodone Sponsors: Tetra Bio-Pharma; Cognitive Research Corporation Recruiting Thu, 21 Jun 2018 12:00:00 EDT Observational Prospective Study of Opiate-free Anesthesia for Anterior Total Hip ReplacementConditions: Rehabilitation; Analgesia; AnesthesiaIntervention: Drug: Cumulative morphine consumption Sponsor: Hôpital Privé Sévigné Completed Wed, 02 Oct 2019 12:00:00 EDT Perioperative Methadone Use to Decrease Opioid Requirement in Pediatric Spinal Fusion PatientsConditions: Scoliosis; PainInterventions: Drug: Methadone; Other: Normal Saline; Drug: Morphine Sponsor: Medical College of Wisconsin Recruiting Wed, 23 Sep 2015 12:00:00 EDT Effect of Ramosetron in Prevention of Intrathecal Morphine Induced Nausea and VomitingCondition: Postoperative Nausea and VomitingInterventions: Drug: ramosetron; Drug: Ondansetron Sponsor: Thammasat University Completed Wed, 13 Jul 2016 12:00:00 EDT
Duloxetine Potentiates the Analgesic Efficacy of Intrathecal MorphineCondition: Acute PainInterventions: Drug: Duloxetine 60mg; Drug: placebo Sponsor: Assiut University Completed Mon, 18 Jun 2018 12:00:00 EDT Opioids for Refractory Breathlessness in Chronic Obstructive Pulmonary DiseaseConditions: Chronic Obstructive Pulmonary Disease; DyspneaInterventions: Drug: Morphine sulfate; Drug: Placebo Sponsor: Flinders University Withdrawn Wed, 27 May 2015 12:00:00 EDT Dexmedetomidine Use in Infants Undergoing Cooling Due to Neonatal Encephalopathy (DICE Trial)Conditions: Hypoxic-Ischemic Encephalopathy; PainInterventions: Drug: Dexmedetomidine Hydrochloride; Drug: Morphine Sulfate Sponsor: University of Utah Not yet recruiting Fri, 26 Feb 2021 12:00:00 EST RCT Comparing the Analgesic Efficacy of 4 Therapeutic Strategies Based on 4 Different Major Opioids (Fentanyl, Oxycodone, Buprenorphine vs Morphine) in Cancer Patients With Moderate/Severe Pain, at the Moment of Starting 3rd Step of WHO Analgesic Ladder.Conditions: Cancer; Cancer PainInterventions: Drug: Morphine; Drug: Fentanyl; Drug: Buprenorphine; Drug: Oxycodone Sponsor: Mario Negri Institute for Pharmacological Research Completed Tue, 12 Mar 2013 12:00:00 EDT Palliative Morphine With or Without Concurrent ModafinilConditions: Cancer; Pain Palliation; Excessive SleepinessInterventions: Drug: Modafinil; Drug: Placebo Sponsor: Dr. Rajendra Prasad Government Medical College Unknown status Fri, 11 Jan 2013 12:00:00 EST Altered Drug Disposition and Biomarkers for Diagnosis of Chronic Inflammatory Liver DiseaseCondition: Fatty LiverInterventions: Other: High fat meal; Drug: Morphine Sponsors: University of North Carolina, Chapel Hill; University of North Carolina, Greensboro Completed Fri, 11 Jan 2013 12:00:00 EST Multisystemic Therapy (MST) for Obesity in African American YouthCondition: ObesityInterventions: Behavioral: Multisystemic Therapy (MST); Behavioral: Shapedown Sponsors: Wayne State University; American Diabetes Association Completed Wed, 30 Jan 2008 12:00:00 EST Sequential and Mixture Injection of Opioids and Hyperbaric BupivacaineConditions: Bupivacaine Adverse Reaction; Regional Anesthesia Morbidity; Cesarean Section ComplicationsIntervention: Drug: Bupivacaine-fentanyl-Morphine. Sponsor: Assiut University Completed Wed, 27 May 2020 12:00:00 EDT Hydrocodone/Acetaminophen for Acute Pain Following BunionectomyCondition: PainInterventions: Drug: Hydrocodone/Acetaminophen Extended Release; Drug: Acetaminophen; Drug: Morphine Extended Release; Drug: Placebo Sponsor: AbbVie (prior sponsor, Abbott) Completed Thu, 24 Dec 2009 12:00:00 EST Non-interventional Study to Assess Adherence to Treatment for Patients With RMS (MAIN-MS)Condition: Relapsing Multiple Sclerosis (RMS)Intervention: Drug: Rebif (Interferon beta-1a) Sponsors: Merck KGaA, Darmstadt, Germany; Merck Serono Middle East FZ LLC Completed Fri, 30 Sep 2016 12:00:00 EDT
The Efficacy of Serratus Anterior Plane Block (ESAPB) for Thoracotomy: a Prospective StudyConditions: Pain, Postoperative; Anesthesia; ThoracotomyInterventions: Procedure: Serratus anterior plane block; Drug: Intravenous patient-controlled-analgesia morphine Sponsor: Shanghai Zhongshan Hospital Completed Fri, 15 Feb 2019 12:00:00 EST Comparison of Efficacy and Safety of the Postoperative Analgesia MethodsCondition: Supratentorial NeoplasmsInterventions: Drug: Morphine; Drug: Dexketoprofen; Drug: Placebo Sponsor: Istanbul University Unknown status Tue, 11 Oct 2016 12:00:00 EDT The Analgesic Efficacy of Bilateral Erector Spinae Plane Block in Comparison With Intrathecal Morphine After Elective Cesarean SectionCondition: Postoperative PainIntervention: Procedure: Erector Spinae Plane Block Sponsor: Fayoum University Completed Thu, 02 May 2019 12:00:00 EDT Impact of Dexmedetomidine on Sleep QualityConditions: Elderly; Surgery; Analgesia; Dexmedetomidine; Complication,Postoperative; Sleep QualityInterventions: Drug: Dexmedetomidine; Drug: Placebo Sponsor: Peking University First Hospital Completed Tue, 18 Apr 2017 12:00:00 EDT Ketamine for Acute Painful Crisis in Sickle Cell Disease PatientsCondition: Sickle Cell CrisisInterventions: Drug: Morphine Group; Drug: Ketamine Group; Other: standard IV hydration Sponsor: Dammam University Unknown status Tue, 13 Feb 2018 12:00:00 EST Thoracic Paravertebral Blocks in Open NephrectomyConditions: Nephrectomy; AnalgesiaInterventions: Drug: Ropivacaine; Drug: Morphine Sponsors: Asklepieion Voulas General Hospital; Michail Tsagkaris; Chryssoula Staikou; Ioannis Karavokyros Unknown status Fri, 09 Feb 2018 12:00:00 EST A Study to Compare Patient-controlled Pain Medications Delivered Either Through the Skin or IntravenouslyConditions: Pain; Analgesia, Patient-Controlled; Pain, PostoperativeInterventions: Drug: IONSYS (fentanyl HCl) Iontophoretic TransdermalSystem; Drug: IV Morphine Patient-Controlled Analgesia (IV PCA) Sponsors: Janssen-Cilag International NV; Alza Corporation, DE, USA Completed Fri, 16 Oct 2009 12:00:00 EDT Dose Finding Study of STR-324Condition: Pain, AcuteInterventions: Drug: Morphine; Drug: Morphine HCl; Drug: STR-324 Sponsor: Alaxia SAS Recruiting Mon, 12 Oct 2020 12:00:00 EDT Methadone Demonstration Project With Neonatal Intensive Care Unit Infants Diagnosed With Neonatal Abstinence SyndromeCondition: Neonatal Abstinence SyndromeInterventions: Drug: Methadone; Drug: Morphine Sponsors: Johns Hopkins All Children's Hospital; Florida Department of Health Terminated Mon, 01 May 2017 12:00:00 EDT Efficacy of Sublingual Midazolam in Association With Oral Morphine in Children Analgesia After Bone FractureCondition: FracturesInterventions: Drug: Midazolam; Drug: Placebo Sponsor: Assistance Publique - Hôpitaux de Paris Completed Wed, 27 Dec 2006 12:00:00 EST
Intrathecal Morphine for Robotic-assisted Laparoscopic Hysterectomy.Condition: Opioid-Related DisordersIntervention: Procedure: Robotic-assisted hysterectomy Sponsor: Karlstad Central Hospital Recruiting Sat, 19 Dec 2020 12:00:00 EST Impact of Morphine Treatment on Platelet Inhibition in Acute Myocardial InfarctionCondition: Acute Myocardial InfarctionInterventions: Drug: Morphinhydrochloricum; Drug: Metoclopramide; Drug: Ticagrelor; Drug: Isotonic sodium chloride Sponsor: University of Luebeck Completed Fri, 11 Dec 2015 12:00:00 EST Attention and Memory Disorders Related to Acute MorphineCondition: Memory DisordersIntervention: Other: Two tests evaluating memory and attention Sponsor: University Hospital, Toulouse Unknown status Wed, 25 Apr 2018 12:00:00 EDT Efficacy and Safety Study of Nasalfent for Treatment of Breakthrough Cancer Pain in Patients Taking Regular OpioidsCondition: Cancers, PainInterventions: Drug: Fentanyl citrate; Drug: Immediate release morphine sulphate Sponsor: Archimedes Development Ltd Completed Thu, 10 Jan 2008 12:00:00 EST Serratus Intercostal Plane Block,New Analgesia in Supraumbilical SurgeryConditions: Postoperative Pain; Analgesia; Local Anaesthetic; Abdominal InjuryInterventions: Procedure: fascial block as postoperative analgesia; Drug: Morphine; Device: PCA CADD Smith Medical pumps Sponsor: Hospital Medina del Campo Completed Mon, 24 Feb 2020 12:00:00 EST Effect of Thoracic Epidural Analgesia for Thoracotomy on the Occurrence of AFConditions: Posterolateral Thoracotomy; Lung Resection; Thoracic Epidural Analgesia; Sympathetic Outflow; Atrial FibrillationInterventions: Other: Thoracic Epidural Analgesia (TEA); Other: TEA followed by Intravenous morphine Sponsor: Larissa University Hospital Unknown status Wed, 31 Oct 2012 12:00:00 EDT U/S-guided Continuous Quadratus Lumborum Block III in Percutaneous NephrolithotomyConditions: Analgesia; Surgery; Renal StoneInterventions: Procedure: Continous Quadratum Lumborum Block III; Procedure: Single dose Quadratum Lumborum Block III; Procedure: Intra-venous Morphine Sponsor: Nazmy Edward Seif Recruiting Tue, 16 Mar 2021 12:00:00 EDT Perioperative Analgesic Modalities for Breast Cancer SurgeriesCondition: AnalgesiaInterventions: Procedure: serratus plane block; Procedure: erector spinae block; Drug: Morphine Sulfate Sponsor: National Cancer Institute, Egypt Completed Thu, 30 Jan 2020 12:00:00 EST Reduced Opioid Analgesic Requirements Via Improved Endogenous Opioid FunctionCondition: Chronic PainInterventions: Behavioral: 6 week aerobic exercise intervention; Drug: Placebo; Drug: Morphine; Drug: naloxone Sponsors: Vanderbilt University Medical Center; National Institute on Drug Abuse (NIDA) Completed Thu, 11 Jun 2015 12:00:00 EDT Influence of Opioid Analgesia on Circulating Tumor Cells in Open Colorectal Cancer SurgeryConditions: Colorectal Cancer; Circulating Tumor CellInterventions: Drug: Morphine; Drug: Piritramid; Drug: Epidural Sponsors: The Institute of Molecular and Translational Medicine, Czech Republic; General University Hospital, Prague; Tomas Bata Hospital, Czech Republic; University Hospital Ostrava; Hospital Novy Jicin Recruiting Tue, 09 Oct 2018 12:00:00 EDT
Testing MST to Improve Adherence Among Youth With Chronic Poor Metabolic ControlCondition: Type 1 DiabetesIntervention: Behavioral: Multisystemic Therapy Sponsors: Wayne State University; National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Medical University of South Carolina Completed Thu, 23 Aug 2007 12:00:00 EDT Adductor Canal Block and Recovery After Total Knee Replacement SurgeryCondition: Total Knee ArthroplastyInterventions: Drug: Adductor Canal Block; Drug: Adductor Canal Block with Morphine; Drug: Local Infiltration Sponsor: University Health Network, Toronto Completed Wed, 08 Apr 2015 12:00:00 EDT Ultrasound-assisted Bilateral Transversus Abdominis Plane Block for Open ProstatectomyConditions: Prostatectomy; Transversus Abdominis Plane Blockade; PainInterventions: Procedure: Transversus abdominis plane blockade; Procedure: Morphine-patient-controlled-analgesia-device Sponsor: Charite University, Berlin, Germany Completed Thu, 21 Jun 2012 12:00:00 EDT Magnetic Seizure Therapy (MST) for the Treatment of Major DepressionCondition: Major Depressive DisorderInterventions: Device: Magstim Theta; Device: Thymatron System IV Sponsors: Sarah Lisanby; University of Texas; Stanley Medical Research Institute Completed Wed, 09 Sep 2009 12:00:00 EDT Morphine for the Treatment of Pain in Patients With Breast CancerCondition: PainInterventions: Drug: fentanyl citrate; Drug: morphine sulfate Sponsor: Roswell Park Cancer Institute Completed Fri, 30 Jul 2004 12:00:00 EDT Effectiveness of Bilateral Ultrasound-Guided Erector Spinae Plane BlockCondition: Erector Spinae Plane BlockInterventions: Drug: Bilateral Ultrasound-Guided Erector Spinae Plane Block; Drug: Morphine Consumption Sponsor: Cairo University Completed Tue, 01 Oct 2019 12:00:00 EDT Morphine-Midazolam in Pre-hospital Traumatic Patients With Severe Acute PainCondition: Acute Traumatic PainIntervention: Drug: Midazolam Sponsors: Centre Hospitalier de Cornouaille; Ministry of Health, France Completed Wed, 21 Nov 2012 12:00:00 EST The ReModel IHC Study for ESRD PatientsCondition: Dialysis Access MalfunctionIntervention: Device: Alio Medical Remote Monitoring System (RMS) Sponsor: Alio Medical Not yet recruiting Thu, 09 Sep 2021 12:00:00 EDT Effects of General Anesthesia and Spinal-Morphine Anesthesia on Recovery and Comfort After Benign Abdominal HysterectomyCondition: Hysterectomy (MeSH nr: E04.950.300.399)Interventions: Drug: Bupivacain; Drug: Morphine; Drug: Propofol; Drug: Fentanyl; Drug: Rocuronbromid Sponsor: Preben Kjolhede Completed Mon, 10 Sep 2007 12:00:00 EDT Intrathecal Morphine Administration Using Implantable Pump With Continuous or Programmable FlowConditions: Advanced Cancer; Intractable PainInterventions: Device: Implantable pump with continuous flow; Device: Implantable pump with programmable flow. Sponsor: Institut Cancerologie de l'Ouest Completed Fri, 30 Mar 2012 12:00:00 EDT
Liposomal Bupivacaine in Total Knee ArthroplastyConditions: Pain, Postoperative; Arthroplasty, Replacement, Knee; OsteoarthritisInterventions: Drug: Liposomal bupivacaine; Drug: bupivacaine HCl, morphine, epinephrine, methylprednisolone Sponsors: Miller Orthopedic Specialists; Creighton University Medical Center; CHI Health Mercy Hospital Withdrawn Fri, 24 Apr 2015 12:00:00 EDT Efficacy and Safety of Ultra-low Dose Methadone as Adjuvant Analgesic in Cancer Patients With PainCondition: Pain, IntractableInterventions: Drug: oral methadone; Drug: oral morphine Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre Unknown status Mon, 22 Feb 2016 12:00:00 EST Post-cesarean Pain Control Via Continuous Infusion of Ropivacain et Diclogenac Into the Wound Versus Intathecal MorphineCondition: Cesarean SectionInterventions: Drug: Reference; Drug: Experimental Sponsor: Centre Hospitalier Universitaire de Nīmes Withdrawn Wed, 29 Sep 2010 12:00:00 EDT An Efficacy and Safety Study of Transdermal Therapeutic System (TTS)-Fentanyl in Thai Participants With Chronic Non-Malignant PainCondition: Chronic PainInterventions: Drug: TTS-Fentanyl; Drug: Morphine Sponsor: Janssen-Cilag Ltd.,Thailand Completed Fri, 22 Mar 2013 12:00:00 EDT A Comparison Trial Between PCA and Epidural Analgesia for Pectus Excavatum RepairCondition: Pectus ExcavatumInterventions: Drug: Hydromorphone; Drug: Morphine Sponsor: Baylor College of Medicine Terminated Wed, 05 Feb 2014 12:00:00 EST Pain Treatment for SciaticaConditions: Radiculopathy; SciaticaInterventions: Drug: Nortriptyline; Drug: Morphine Sponsor: National Institute of Dental and Craniofacial Research (NIDCR) Completed Mon, 05 Feb 2001 12:00:00 EST Epidural vs. Wound Catheter Following Liver ResectionCondition: Transplant SurgeryIntervention: Procedure: This arm will received perioperative transversus abdominis plane (TAP) block followed by continuous infusion of local anaestheic by wound catheters and an IV morphine PCA. Sponsor: The Leeds Teaching Hospitals NHS Trust Completed Mon, 20 Aug 2018 12:00:00 EDT A Health Economic Trial in Adult Patients Undergoing Laparoscopic ColectomyCondition: Bowel ObstructionInterventions: Drug: IV morphine sulfate or Sponsor-approved equivalent; Drug: EXPAREL Sponsors: Pacira Pharmaceuticals, Inc; Registrat-Mapi Terminated Mon, 10 Feb 2014 12:00:00 EST Intravenous Acetaminophen and Morphine Versus Intravenous Morphine Alone for Acute Pain in the Emergency DepartmentCondition: Pain ManagementInterventions: Drug: placebo of acetaminophen IV; Drug: acetaminophen IV Sponsor: Nantes University Hospital Recruiting Fri, 01 Nov 2019 12:00:00 EDT Methadone in Pediatric and Adult Sickle Cell PatientsCondition: Sickle Cell DiseaseInterventions: Drug: Morphine; Drug: Methadone Sponsor: Washington University School of Medicine Completed Fri, 26 Sep 2008 12:00:00 EDT
Comparison of Low-dose Epidural With Intravenous Narcotic Versus Intravenous Narcotic AloneCondition: PainIntervention: Drug: Bupivacaine, Clonidine, Morphine Sponsor: University of North Carolina, Chapel Hill Terminated Mon, 06 Feb 2006 12:00:00 EST Pregabalin, Celecoxib, Total Knee Arthroplasty and Intrathecal MorphineConditions: Postoperative Pain Management; Total Knee ArthroplastyInterventions: Drug: Pregabalin; Drug: Celecoxib; Drug: Pregabalin with celecoxib; Drug: Placebo Sponsors: Chulalongkorn University; Bhumibol Adulyadej Hospital; King Chulalongkorn Memorial Hospital Completed Fri, 29 Apr 2011 12:00:00 EDT Switching From Morphine to Methadone. A Clinical, Pharmacological and Pharmacogenetic StudyCondition: CancerIntervention: Drug: Methadone Sponsor: Norwegian University of Science and Technology Completed Fri, 16 Sep 2005 12:00:00 EDT Transversus Abdominis Plane Block for Postoperative Analgesia in Living Donor HepatectomyCondition: Acute PainInterventions: Drug: Transversus Abdominis Plane Block; Drug: standard general anesthesia Sponsor: Inonu University Completed Tue, 05 Jan 2016 12:00:00 EST High Frequency Oscillatory Ventilation for Acute Respiratory Distress Syndrome (ARDS)Condition: Acute Respiratory Distress SyndromeInterventions: Device: Lung protective CMV; Device: HFO-RMs Sponsors: University of Athens; University of Thessaly Terminated Wed, 23 Nov 2011 12:00:00 EST A Trial of SHR0410 Injection for the Treatment of Pain After Endoscopic Surgery of the Lower AbdominalCondition: PainInterventions: Drug: SHR0410 Injection; Drug: Placebo; Drug: Morphine Sponsor: Jiangsu HengRui Medicine Co., Ltd. Not yet recruiting Wed, 21 Apr 2021 12:00:00 EDT Efficacy of Caudal Block on Intra-operative Anal Sphincter Muscle Tone and Post-operative Analgesia During Anal Sphincter Sparing Procedures Under General AnaesthesiaCondition: Efficacy of Caudal Block on Intra-operative Anal Sphincter Muscle ToneInterventions: Procedure: Caudal block; Drug: Morphine Sponsor: Kasr El Aini Hospital Not yet recruiting Thu, 03 Dec 2020 12:00:00 EST A Study to Evaluate Buprenorphine Transdermal Patch in Chinese Subjects With Moderate to Severe Chronic Cancer PainCondition: Cancer PainInterventions: Drug: Buprenorphine transdermal patches; Drug: Morphine Sulfate Sustained-Release Tablet Sponsor: Mundipharma (China) Pharmaceutical Co. Ltd Unknown status Thu, 30 May 2019 12:00:00 EDT Nasal Fentanyl And Renal ColicCondition: Acute Renal ColicInterventions: Drug: FENTANYL; Drug: Ketorolac Tromethamine AND morphine Sponsor: Valduce Hospital Completed Wed, 20 Apr 2011 12:00:00 EDT Comparing Individualized vs. Weight Based Protocols to Treat VOE in SCD Occlusive Episodes in Sickle Cell DiseaseCondition: Sickle Cell DiseaseInterventions: Other: Patient-Specific Protocol; Other: Weight-based Protocol; Drug: Morphine; Drug: Hydromorphone Sponsors: Duke University; National Heart, Lung, and Blood Institute (NHLBI) Recruiting Wed, 01 May 2019 12:00:00 EDT
Effects of Anaesthesia on Inflammatory MarkersCondition: Inflammatory ResponseInterventions: Drug: Morphine Sulfate; Drug: morphine+lidocaine; Drug: Saline Sponsor: Assiut University Recruiting Mon, 16 Nov 2020 12:00:00 EST VAS Correlation With BMICondition: Morbid ObesityIntervention: Drug: Morphine Sponsor: Istanbul University Unknown status Fri, 20 Dec 2013 12:00:00 EST Evaluation of Peripheral Itch Mechanisms Following Injection of Morphine (Second Sub-Project)Condition: ItchInterventions: Drug: Capsaicin; Drug: Diphenhydramine; Drug: Morphine Chloride; Drug: Isotonic saline; Drug: Histamine Sponsor: Aalborg University Recruiting Thu, 07 Jan 2021 12:00:00 EST Influence of Anesthetic Temperature on Cephalad Sensory Blockade With Spinal AnesthesiaCondition: Cesarean DeliveryIntervention: Drug: bupivacaine/fentanyl/morphine Sponsor: Nanjing Medical University Completed Mon, 29 Dec 2008 12:00:00 EST CLoWI Versus PCA Morphine for Pain Control After Major Abdominal SurgeryConditions: Surgical Wound; Post-Op Complication; Opioid UseInterventions: Device: CLoWI; Device: PCA Sponsor: JurongHealth Recruiting Fri, 07 Aug 2020 12:00:00 EDT Use of ACUPUNCTURE in Emergency DepartementConditions: Age ≥18 Years; Presigned Consentement to Participate in the StudyIntervention: Procedure: Acupuncture Sponsor: University of Monastir Completed Tue, 19 Jun 2012 12:00:00 EDT Robot-assisted Lobectomy Versus Video-assisted LobectomyConditions: Robotic Surgical Procedures; Pneumonectomy; Status; Anesthesia and Analgesia; Cardiac OutputInterventions: Drug: Morphine; Other: Cardiac output measure Sponsors: Hospital Nord; Gary DUCLOS (Medical Doctor, investigator) Completed Thu, 13 Apr 2017 12:00:00 EDT Acute Post-operative Pain in Colon ResectionsCondition: AnalgesiaInterventions: Device: Sublingual sufentanil tablet system; Device: Peridural catheter; Drug: PCA Morphine Sponsor: IRCCS San Raffaele Unknown status Fri, 19 Jan 2018 12:00:00 EST Fentanyl Sublingual Tablet or Morphine for the Control of Shortness of Breath During or After Physical Activity in Cancer PatientsConditions: Hematopoietic and Lymphoid Cell Neoplasm; Malignant Solid NeoplasmInterventions: Drug: Fentanyl Citrate Buccal Tablet; Drug: Morphine; Other: Physical Performance Testing; Other: Placebo Administration; Other: Quality-of-Life Assessment; Other: Questionnaire Administration Sponsors: M.D. Anderson Cancer Center; National Cancer Institute (NCI) Not yet recruiting Thu, 05 Dec 2019 12:00:00 EST Combined Anesthesia for Laparoscopy Surgery in GynecologyCondition: PainIntervention: Procedure: Spinal anesthesia with Fentanyl+ Morphine Sponsor: Rambam Health Care Campus Unknown status Tue, 23 Nov 2010 12:00:00 EST
Does IV Ondansetron Prevent Pruritus After Intrathecal Morphine in Pediatric Patients?Conditions: Pruritus; Nausea/VomitingInterventions: Drug: Ondansetron; Drug: Placebo Comparator Sponsor: University of Michigan Terminated Fri, 25 Aug 2017 12:00:00 EDT Treatment for Chronic Pain in Patients With Advanced CancerConditions: Chronic Myeloproliferative Disorders; Leukemia; Lymphoma; Multiple Myeloma and Plasma Cell Neoplasm; Myelodysplastic Syndromes; Pain; Precancerous/Nonmalignant Condition; Small Intestine Cancer; Unspecified Adult Solid Tumor, Protocol SpecificInterventions: Drug: dextromethorphan hydrobromide; Drug: morphine sulfate Sponsor: NCIC Clinical Trials Group Completed Mon, 27 Jan 2003 12:00:00 EST Sensory Effects of Oral Opioid Treatment in Patients With Chronic Low Back PainCondition: Low Back PainInterventions: Drug: Oxycodone or morphine sulfate immediate release (MSIR); Drug: Placebo Treatment Sponsors: Brigham and Women's Hospital; National Institute on Drug Abuse (NIDA) Recruiting Wed, 06 Jul 2016 12:00:00 EDT Comparing Acute Pain Management Protocols for Patients With Sickle Cell DiseaseCondition: Sickle Cell DiseaseInterventions: Drug: Hydromorphone (Standardized, weight-based dosing); Drug: Morphine Sulfate (Standardized, weight-based dosing); Drug: Hydromorphone (Patient Specific dosing); Drug: Morphine Sulfate (Patient Specific dosing) Sponsors: Duke University; National Institutes of Health (NIH); National Heart, Lung, and Blood Institute (NHLBI); University of Cincinnati; Mount Sinai Hospital, New York Completed Thu, 21 Aug 2014 12:00:00 EDT Adding Intra-articular Dexmedetomidine to Levobupivacaine for Postoperative Analgesia in Arthroscopic Knee SurgeryCondition: PainInterventions: Drug: Levobupivacaine; Drug: Dexmedetomidine; Drug: Morphine Sponsor: TC Erciyes University Completed Thu, 08 Aug 2013 12:00:00 EDT Bupivacaine Liposome Suspension Versus a Concentrated Multi Drug Periarticular InjectionCondition: Total Knee ArthroplastyInterventions: Drug: bupivacaine liposome suspension; Drug: concentrated multi drug Ketorlac, Morphine PF, Epinephrine, Ropivicaine, 0.9% NaCL Sponsor: TriHealth Inc. Completed Mon, 24 Nov 2014 12:00:00 EST Trial to Shorten Pharmacologic Treatment of Newborns With Neonatal Opioid Withdrawal Syndrome (NOWS)Condition: Neonatal Opioid Withdrawal SyndromeInterventions: Drug: Morphine; Drug: Methadone Sponsors: Advancing Clinical Trials in Neonatal Opioid Withdrawal (ACT NOW) Program; Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Recruiting Thu, 02 Jan 2020 12:00:00 EST Antinociceptive Modalities on Ischemia Reperfusion InjuryConditions: End Stage Liver Disease; Lung CancerIntervention: Drug: Patient controlled analgesia Sponsor: National Taiwan University Hospital Completed Fri, 30 Aug 2013 12:00:00 EDT Taste Acuity and Caloric Intake After Acute Morphine AdministrationConditions: Taste Sweet; Taste Salty; Feeding BehaviorInterventions: Behavioral: taste acuity assessment; Behavioral: Recorded meal Sponsors: Johns Hopkins University; National Institute on Drug Abuse (NIDA) Completed Wed, 09 Jan 2013 12:00:00 EST Effect of Dexmedetomidine on Gastric Emptying and Gastrointestinal TransitConditions: Gastric Emptying; HealthyInterventions: Drug: Dexmedetomidine; Drug: Morphine; Drug: Placebo Sponsors: University of Turku; University of Helsinki Completed Wed, 10 Mar 2010 12:00:00 EST
Decreasing REcurrent Pain and Anxiety in Medical Procedures With a Pediatric Population: TrialConditions: Pain; Burns; Child; AnxietyInterventions: Device: VR distraction via Oculus Rift; Drug: Morphine Sponsor: St. Justine's Hospital Withdrawn Thu, 27 Oct 2016 12:00:00 EDT Multimodal Analgesia in Major Abdominal Pediatric Cancer SurgeriesConditions: Pediatric Cancer; Pain, PostoperativeInterventions: Drug: Paracetamol and ketamine; Procedure: Caudal levobupivacaine; Drug: Morphine Sponsor: National Cancer Institute, Egypt Completed Tue, 10 Jul 2018 12:00:00 EDT A Health Economic Trial in Adult Patients Undergoing Ileostomy Reversal MA402S23B504Condition: Retraction of ColostomyInterventions: Drug: IV morphine sulfate or Sponsor-approved equivalent; Drug: EXPAREL Sponsors: Pacira Pharmaceuticals, Inc; Registrat-Mapi Completed Fri, 13 Jan 2012 12:00:00 EST Lidocaine Infusion or Quadratus Lumborum Block and Intrathecal Morphine, Versus Intrathecal Morphine AloneCondition: Gynecologic CancerInterventions: Drug: Lidocaine Bolus Infusion; Procedure: QL block; Drug: Saline Bolus Infusion; Procedure: Simulated QL block Sponsor: University of Alabama at Birmingham Terminated Wed, 05 Sep 2018 12:00:00 EDT Study in Healthy Volunteers to Investigate the Effects of Quinidine on the Pharmacokinetics of NKTR-118Condition: Drug Induced ConstipationInterventions: Drug: Nektar 118; Drug: Quinidine; Drug: Quinidine placebo; Drug: Morphine Sponsor: AstraZeneca Completed Wed, 15 Feb 2012 12:00:00 EST How to Treat Opiate Withdrawal in NeonatesCondition: Neonatal Abstinence SyndromeInterventions: Drug: Phenobarbital; Drug: Chlorpromazine; Drug: Morphine Sponsor: University of Zurich Completed Thu, 23 Jun 2016 12:00:00 EDT Efficacy of Acupuncture for Prophylaxis of Intrathecal Morphine Induced Pruritis in Patients Undergoing Caesarean DeliveryConditions: Acupuncture; Morphine Induced PruritisInterventions: Device: ACUPUNCTURE AT LI11; Device: SHAM ACUPUNCTURE Sponsor: Letterkenny General Hospital Completed Wed, 26 Jan 2011 12:00:00 EST Functional Restoration After Abdominal and Pelvic Laparoscopic Surgery: Effect of Perioperative Intravenous LidocaineConditions: Colon Cancer; Inflammatory Bowel Diseases; DiverticulitisInterventions: Drug: Lidocaine; Procedure: Epidural Block; Drug: PCA Morphine Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre Completed Wed, 23 Sep 2009 12:00:00 EDT Gene Polymorphisms and Morphine Analgesic ConsumptionConditions: Gene; PolymorphosisIntervention: Sponsors: Hamad Medical Corporation; Qatar University Recruiting Mon, 09 Nov 2020 12:00:00 EST Erector Spinae Block, Epidural Analgesia and Intrathecal Analgesia in Thoracic SurgeryCondition: Pulmonary SurgeryInterventions: Procedure: Epidural anesthesia; Procedure: Intrathecal morphine; Procedure: Erector spinae block Sponsor: University Hospital, Angers Unknown status Fri, 01 Nov 2019 12:00:00 EDT
Genetic Predictors of Analgesic Efficacy of Propranolol for Treating Postoperative PainCondition: Postoperative PainInterventions: Drug: Propranolol PO; Drug: IV-PCA morphine; Drug: Placebo PO; Procedure: Quantitative Sensory Testing (QST); Other: Psychometric assessment; Genetic: COMT-haplotypes Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre Terminated Thu, 30 Jul 2015 12:00:00 EDT Multimodal Perioperative Pain ManagementCondition: Degenerative SpondylolisthesisInterventions: Drug: Postoperative epidural morphine; Drug: Local anaesthesia Sponsors: Northern Orthopaedic Division, Denmark; Vejle Hospital; Aarhus University Hospital; Copenhagen University Hospital, Denmark Completed Fri, 20 Jan 2012 12:00:00 EST Comparison of a Pain Pump Versus Injectable Medication for Analgesia in Knee ArthroscopyCondition: PainInterventions: Device: pain pump containing ropivacaine; Device: saline pain pump with injectable medication; Drug: ropivacaine, ketorolac , morphine sulfate Sponsor: University of South Alabama Completed Wed, 17 Nov 2010 12:00:00 EST The Analgesic Efficacy of Ultrasound Guided Transversus Abdominal Plane Block After Abdominal Cancer SurgeriesCondition: Abdominal CancerInterventions: Drug: Bupivacaine (Transversus Abdominis Plane Block); Drug: Intravenous Patient Controlled Analgesia (PCA) Morphine Sponsor: Rajiv Gandhi Cancer Institute & Research Center, India Completed Wed, 24 May 2017 12:00:00 EDT Early Parecoxib Usage to Decreases Narcotic Requirement and Length of Stay After Traumatic Rib FractureConditions: Parecoxib; Rib FracturesInterventions: Drug: Parecoxib; Drug: Morphine Sponsor: Chang Gung Memorial Hospital Terminated Mon, 25 Apr 2016 12:00:00 EDT Activity Monitoring Assessment of Opiate Withdrawal - 4Condition: Opioid-Related DisordersIntervention: Drug: Morphine Sponsors: National Institute on Drug Abuse (NIDA); Washington D.C. Veterans Affairs Medical Center Completed Tue, 21 Sep 1999 12:00:00 EDT Spinal Anesthetic for Hip and Knee Replacement Surgery - Intrathecal Morphine or HydromorphoneCondition: Spinal AnesthesiaIntervention: Procedure: spinal anesthesia Sponsor: Hopital Montfort Not yet recruiting Fri, 21 Feb 2020 12:00:00 EST NSAIDs With Morphine-PCA Compared to Epidural Analgesia in Thoracotomy PainCondition: Postoperative PainInterventions: Drug: Diclofenac; Drug: parecoxib/ valdecoxib; Device: patient controlled epidural analgesia Sponsors: Helsinki University Central Hospital; Academy of Finland Completed Wed, 29 Feb 2012 12:00:00 EST Intrathecal Opioid StudyCondition: Post-operative PainInterventions: Drug: Morphine100; Drug: Morphine50; Drug: Fentanyl; Drug: Hyperbaric Bupivicaine; Drug: Indomethacin Sponsor: University of Witwatersrand, South Africa Completed Fri, 16 Oct 2015 12:00:00 EDT Cordotomy in Reducing Pain in Patients With Advanced CancerCondition: Advanced Malignant NeoplasmInterventions: Procedure: Cordotomy; Drug: Morphine; Other: Questionnaire Administration; Procedure: Sham Intervention Sponsors: M.D. Anderson Cancer Center; National Cancer Institute (NCI); National Institute of Nursing Research (NINR) Recruiting Tue, 08 Oct 2019 12:00:00 EDT
A Trial to Evaluate CG5503 Efficacy and Safety in Acute Pain After BunionectomyConditions: Bunionectomy; Pain; Postoperative Pain; Acute PainInterventions: Drug: CG5503 IR; Drug: Morphine; Drug: Placebo Sponsors: Grünenthal GmbH; Johnson & Johnson Pharmaceutical Research & Development, L.L.C. Completed Thu, 07 Feb 2008 12:00:00 EST Epidural Versus Wound Infusion Plus Morphine Bolus in Open Abdominal Aortic Aneurysm RepairCondition: Postoperative PainInterventions: Drug: Paracetamol; Drug: Levobupivacaine wound infiltration; Drug: Levobupivacaine epidural bolus; Drug: Sufentanil epidural bolus; Drug: Morphine; Device: Epidural catheter placement; Device: Wound infusion catheters placement; Drug: Levobupivacaine plus sufentanil epidural infusion; Drug: Levobupivacaine wound infusion Sponsor: University of Genova Completed Tue, 09 Feb 2016 12:00:00 EST Erector Spinae Plane Block for Post-nephrectomy PainCondition: Pain, PostoperativeInterventions: Procedure: Morphine patient controlled analgesia; Procedure: Morphine patient controlled analgesia and ESPB Sponsor: National Cancer Institute, Egypt Recruiting Thu, 03 Sep 2020 12:00:00 EDT Supra-inguinal Fascia Iliaca Compartment Block on Postoperative Management in Total Hip Arthroplasty by Posterior ApproachCondition: Arthropathy of HipInterventions: Procedure: Supra-inguinal fascia iliaca compartment block; Drug: Multimodal analgesia and PCA morphine pump Sponsor: University of Liege Recruiting Mon, 05 Oct 2020 12:00:00 EDT Thoracic Paravertebral Blockade in Video Assisted Thoracoscopic Surgery (VATS)Condition: Pain, PostoperativeInterventions: Drug: Thoracic paravertebral block (TPVB); Drug: Patient Controlled Analgesia (IV PCA) Sponsor: Istanbul University Completed Thu, 27 Nov 2014 12:00:00 EST Transversus Abdominis Plane Block and Quadratus Lumborum Block in Pediatric PatientsCondition: Pain, PostoperativeIntervention: Drug: Tramadol hydrochloride Sponsor: Bakirkoy Dr. Sadi Konuk Research and Training Hospital Completed Tue, 24 Dec 2019 12:00:00 EST Efficacy and Safety of Parecoxib on Morphine Patient-controlled Epidural Analgesia (PCEA) After Gynecologic SurgeryCondition: Benign Female Reproductive System NeoplasmInterventions: Drug: Parecoxib Sodium; Drug: Normal saline Sponsors: Liu Weifeng; Guangdong Provincial People's Hospital; Second Affiliated Hospital, Sun Yat-Sen University; Nanfang Hospital of Southern Medical University Completed Thu, 29 Mar 2012 12:00:00 EDT A Study of Immune Phenotype Biomarkers in Patients With Relapsing Multiple Sclerosis (RMS) After Treatment With 0.5mg FingolimodCondition: Relapsing Multiple SclerosisIntervention: Drug: Fingolimod Sponsor: Novartis Pharmaceuticals Completed Tue, 22 Aug 2017 12:00:00 EDT Assessment of Opioid Analgesia in Sickle CellCondition: Sickle Cell DiseaseInterventions: Drug: Dextromethorphan; Drug: Codeine; Drug: Morphine Sponsor: Children's National Research Institute Withdrawn Thu, 09 Aug 2007 12:00:00 EDT Factors Associated With Failed Spinal Anesthesia for Cesarean DeliveryConditions: Anesthesia; Adverse Effect; Cesarean Section ComplicationsIntervention: Procedure: spinal anaesthesia with local anaesthetic and intrathecal morphine Sponsor: Mahidol University Completed Mon, 28 Dec 2020 12:00:00 EST
Comparing 2 Types of Pain Relief After Cesarean Delivery: Spinal Morphine and TAP BlockCondition: Cesarean DeliveryInterventions: Procedure: Placebo block; Procedure: Ultrasound-guided TAP block Sponsor: University of British Columbia Completed Mon, 01 Dec 2008 12:00:00 EST TQLB for Postoperative Pain After Laparoscopic Partial NephrectomyConditions: Laparoscopic Renal Surgery; Pain Management; Nerve BlockInterventions: Procedure: single-injection TQLB(transmuscular quadratus lumborum block); Drug: Morphine given as IPCA(intravenous patient controlled analgesia) Sponsor: Cui Xulei Completed Wed, 12 Jun 2019 12:00:00 EDT Impact of Adductor Canal Block on Functional RecoveryCondition: Total Knee ReplacementInterventions: Procedure: Intrathecal morphine; Procedure: Adductor Canal block; Procedure: Peri-articular Infilteration Sponsor: Assiut University Not yet recruiting Wed, 24 Mar 2021 12:00:00 EDT A Prospective Randomized Comparison of Fentanyl, Methadone and Morphine for Epidural Analgesia in an Experimental Pain ModelCondition: PainIntervention: Drug: Epidural administration of bolus Sponsor: Hadassah Medical Organization Withdrawn Fri, 20 Feb 2009 12:00:00 EST Spinal Anesthesia For Enhanced Recovery After Liver SurgeryConditions: Hepatectomy; Pain, Postoperative; Liver NeoplasmsInterventions: Procedure: Continuous thoracic epidural analgesia; Procedure: Spinal anesthesia with intrathecal morphine; Drug: Bupivacaine 0.75% in Dextrose Inj 8.25%; Drug: Morphine; Drug: Bupivacaine 0.25% Preservative-Free Injectable Solution; Drug: Bupicavaine 0.125% epidural solution; Drug: Hydromorphone 10 mcg/mL epidural solution Sponsor: University of Manitoba Unknown status Tue, 23 Oct 2018 12:00:00 EDT Quadratus Lumborum Block in Pediatric PatientsCondition: Postoperative PainInterventions: Drug: Tramadol Hydrochloride; Drug: Morphine Sulfate Sponsor: Bakirkoy Dr. Sadi Konuk Research and Training Hospital Completed Tue, 02 Oct 2018 12:00:00 EDT Regional Anaesthesia for Painful Injuries After DisastersConditions: Lower Limb Injuries; FractureInterventions: Drug: Bupivacaine (femoral nerve block); Drug: Morphine; Device: Ultrasound Sponsors: Epicentre; Brown University; Medecins Sans Frontieres, Netherlands Withdrawn Thu, 03 Mar 2016 12:00:00 EST Comparison of Low-dose Ketamine to Opioids in the Management of Acute Pain in Patients Presenting to the Emergency Department With Long Bone FracturesCondition: Pain, AcuteInterventions: Drug: Ketamine; Drug: Morphine Sponsor: The University of Texas Health Science Center, Houston Not yet recruiting Mon, 19 Aug 2019 12:00:00 EDT Ultrasound Guided Pain Control Versus Standard Treatment in Emergency Department HIP Fracture PatientsCondition: Hip FractureInterventions: Procedure: UFNB (Ultrasound guided femoral nerve block); Procedure: UFIB (Ultrasound Guided Fascia Iliaca Compartment Block); Drug: IVMS (IV Morphine) Sponsors: Antonios Likourezos; Emergency Medicine Foundation Completed Mon, 22 Jul 2013 12:00:00 EDT Opioid Rotation From Morphine to Methadone in Treatment of Non-malignant PainCondition: Non-malignant Chronic PainIntervention: Drug: Methadone Sponsor: Norwegian University of Science and Technology Completed Tue, 25 Jul 2006 12:00:00 EDT
Efficacy of Hylenex in the Treatment of Pain Among Hospice PatientsCondition: Pain ManagementInterventions: Drug: Hylenex recombinant , morphine, saline; Other: Saline Sponsors: HPC Healthcare, Inc.; Baxter Healthcare Corporation Completed Mon, 22 Oct 2007 12:00:00 EDT Ultrasound-Guided Versus Conventional Injection for Caudal BlockCondition: Ultrasound Therapy; ComplicationsInterventions: Drug: Levobupivacaine; Drug: Morphine Sulfate; Device: Ultrasound Sponsor: Ataturk University Completed Wed, 08 Nov 2017 12:00:00 EST Family-Based Treatment for Parental Substance Abuse and Child MaltreatmentConditions: Substance Abuse; Child Abuse; Child NeglectInterventions: Behavioral: Comprehensive Community Treatment; Behavioral: MST-BSF Sponsor: Medical University of South Carolina Completed Fri, 03 Aug 2012 12:00:00 EDT Cervical Erector Spinae Block for Shoulder SurgeryConditions: Postoperative Pain; Shoulder SurgeryInterventions: Other: Cervical erector spinae plane block; Device: Intravenous morphine patient controlled analgesia device Sponsors: Konya Necmettin Erbakan Üniversitesi; Ataturk University Not yet recruiting Thu, 21 May 2020 12:00:00 EDT Psoas Compartment Block Versus Fascia Iliaca Block After Total Hip ArthroplastyCondition: PainInterventions: Drug: Bupivacaine; Drug: Morphine Sponsor: Hillel Yaffe Medical Center Unknown status Thu, 23 Jun 2011 12:00:00 EDT Efficacy of Intravenous (IV) Paracetamol for Treatment of Acute PainCondition: Acute PainIntervention: Drug: Paracetamol Sponsor: Tehran University of Medical Sciences Completed Sun, 06 Nov 2011 12:00:00 EDT Epidural Versus Patient-controlled Analgesia for Reduction in Long-term Mortality Following Colorectal Cancer SurgeryConditions: Colorectal Cancer; Pain; Other ComplicationsInterventions: Drug: Ropivacaine + opioid epidurally; Drug: Morphine Sponsors: Örebro University, Sweden; University Hospital, Linkoeping Terminated Fri, 18 Mar 2011 12:00:00 EDT Trauma Acute Pain Treatment With Methoxyflurane Vaporized (PENTHROX®): Efficacy and Safety Study (MEDITA)Condition: Acute Traumatic PainInterventions: Combination Product: Methoxyflurane and Penthrox inhaler; Drug: Morphine; Drug: Paracetamol; Drug: Ketoprofen Sponsors: Mundipharma Pharmaceuticals srl; Bioikos Ambiente Srl Completed Fri, 13 Jul 2018 12:00:00 EDT Serratus Anterior Plane Block: Post-operative Analgesia in Video-assisted Thoracic SurgeryConditions: Regional Anesthesia; Thoracic Surgery; Post-operative Pain; Post-operative Chronic Pain; Pharmacokinetic Analysis; Serratus Anterior Plane BlockInterventions: Procedure: Serratus anterior plane block; Device: patient-controlled analgesia Sponsor: Université Libre de Bruxelles Unknown status Mon, 11 Sep 2017 12:00:00 EDT The Effect of Double Injection Erector Spinae Plane Block on Postoperative Pain Following Breast SurgeryConditions: Postoperative Pain; Breast CancerInterventions: Other: Erector Spinae Plane Block; Device: Intravenous Morphine patient controlled analgesia device Sponsor: Kocaeli University Completed Tue, 30 Jan 2018 12:00:00 EST
Combination of Peripheral Nerve Block and DepoDur in Total Knee Joint ReplacementCondition: Arthroplasty, Replacement, KneeInterventions: Drug: Depodur; Procedure: sciatic nerve block Sponsors: University of Louisville; EKR Therapeutics, Inc Terminated Fri, 08 May 2009 12:00:00 EDT Multisystemic Therapy-Emerging Adults (MST-EA) for Substance AbuseCondition: Antisocial BehaviorInterventions: Behavioral: Multisystemic Therapy-Emerging Adults; Behavioral: Enhanced Treatment as Usual Sponsors: Oregon Social Learning Center; University of Massachusetts, Worcester; Connecticut Department of Children and Families; North American Family Institute; Court Support Services Division; Youth Villages Recruiting Mon, 30 Jan 2017 12:00:00 EST Erector Spinae Plane Block for Postoperative Analgesia for Laparoscopic CholecystectomyCondition: Postoperative PainInterventions: Other: erector spinae plane block; Device: Intravenous morphine patient controlled analgesia device Sponsor: Kocaeli University Completed Mon, 05 Feb 2018 12:00:00 EST Study to Assess Safety and Preliminary Activity of Eribulin Mesylate in Pediatric Participants With Relapsed/Refractory Rhabdomyosarcoma (RMS), Non-rhabdomyosarcoma Soft Tissue Sarcoma (NRSTS) and Ewing Sarcoma (EWS)Conditions: Relapsed/Refractory Rhabdomyosarcoma; Non-rhabdomyosarcoma Soft Tissue Sarcoma; Ewing SarcomaIntervention: Drug: Eribulin mesylate Sponsor: Eisai Inc. Recruiting Thu, 22 Feb 2018 12:00:00 EST Intravenous Ketamine for Pain Control During First Trimester Surgical AbortionCondition: Abortion in First TrimesterInterventions: Drug: PO Morphine; Drug: IV Fentanyl; Drug: IV Ketamine; Drug: PO Placebo; Drug: IV Placebo Sponsor: Dr. Marie Eve Sophie Bussiere-Cote Suspended Fri, 23 Nov 2018 12:00:00 EST A Brain Imaging Study of Opioid (Morphine) and Non-opioid (Ketorolac) Conditioning EffectsCondition: Healthy ControlsInterventions: Radiation: Integrated MR-PET scan; Drug: Ketorolac Sponsor: Massachusetts General Hospital Completed Thu, 12 Apr 2012 12:00:00 EDT Masked Faces in Parkinson Disease: Mechanism and TreatmentCondition: Parkinson's DiseaseIntervention: Behavioral: Respiratory muscle strength training Sponsors: University of Florida; National Institute of Neurological Disorders and Stroke (NINDS) Completed Mon, 10 Jul 2006 12:00:00 EDT Continuous Paravertebral Block on Postoperative Quality of Recovery After HepatectomyCondition: Nerve BlockInterventions: Procedure: Continuous Paravertebral block with ropivacaine; Procedure: Continuous Paravertebral Block with Saline; Drug: Patient-controlled analgesia with morphine Sponsor: Cui Xulei Completed Mon, 17 Dec 2018 12:00:00 EST Clinical Effectiveness of Erector Spinae Plane Block in Peri-operative Analgesia for Nephrectomy/Nephron Sparing Surgery(NSS) Performed Via LumbotomyCondition: Erector Spinae Plane BlockInterventions: Drug: Morphine PCA pump; Procedure: ESP block; Drug: Fentanyl Sponsors: Medical University of Warsaw; Warsaw Clinical University Center Unknown status Fri, 22 Mar 2019 12:00:00 EDT Epidural Nalbuphine for Postcesarean Epidural Morphine Induced PruritusCondition: Cesarean SectionInterventions: Drug: nalbuphine; Other: NSS Sponsor: Mahidol University Completed Tue, 01 Jul 2008 12:00:00 EDT
Effect of Body Mass Index on the Dose of Intrathecal Hyperbaric Bupivacaine for Elective Cesarean SectionConditions: Pain; ObesityIntervention: Drug: bupivacaine 0.75% with fentanyl and morphine Sponsor: Samuel Lunenfeld Research Institute, Mount Sinai Hospital Completed Mon, 27 Nov 2006 12:00:00 EST General Plus Spinal Anesthesia and General Anesthesia Alone on Right Ventricular FunctionCondition: Right Ventricular DysfunctionInterventions: Procedure: Spinal anesthesia with Bupivacaine heavy and Morphine; Drug: Bupivacaine heavy and Morphine; Drug: General Anesthetics Sponsor: Postgraduate Institute of Medical Education and Research Unknown status Fri, 06 Jan 2017 12:00:00 EST PEF-Block & Ribs FracturesCondition: Chest Trauma With Ribs FracturesInterventions: Procedure: Intravenous morphine patient-controlled analgesia (PCA); Procedure: Block of the posterior exo-thoracic fascia with Ropivacaine; Procedure: Block of paravertebral space with Ropivacaine Sponsor: University Hospital, Montpellier Unknown status Thu, 11 Jan 2018 12:00:00 EST Comparison of Efficacy of Paravertebral and Epidural Analgesia After Videothoracoscopic Lung LobectomyCondition: Lung CancerInterventions: Procedure: Continuous Thoracic Epidural Block; Procedure: Continuous Thoracic Paravertebral Block; Procedure: Patient-Controlled Analgesia with Morphine Sponsor: Pulmonary Hospital Zakopane Completed Mon, 20 Jan 2014 12:00:00 EST Postoperative Analgesic Effect of Hydromorphone on Partial Pulmonary Resection Under Video-assisted ThoracoscopyConditions: Pain, Postoperative; Thoracic Surgery, Video-AssistedInterventions: Drug: Hydromorphone; Drug: Morphine Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University Completed Mon, 27 Aug 2018 12:00:00 EDT Clonidine as Adjunct to Morphine for Neonatal Abstinence SyndromeCondition: Neonatal Abstinence SyndromeInterventions: Drug: Clonidine; Drug: Placebo Sponsor: Hennepin County Medical Center, Minneapolis Suspended Mon, 03 Dec 2018 12:00:00 EST Discontinuation vs Continuation of Long-term Opioid Therapy in Suboptimal and Optimal Responders With Chronic PainConditions: Opioid-Related Disorders; Opiate Addiction; Narcotic Abuse; Drug AbuseInterventions: Drug: Structured discontinuation of opioid therapy (morphine sulfate ER, oxycodone ER, oxymorphone ER); Drug: Continuation of opioid therapy (morphine sulfate ER, oxycodone ER, oxymorphone ER) Sponsor: Member Companies of the Opioid PMR Consortium Terminated Mon, 18 Apr 2016 12:00:00 EDT CSE for Labour Analgesia: A Comparison of Two Intrathecal RegimensCondition: Labor PainInterventions: Drug: Bupivacaine-fentanyl; Drug: Bupivacaine-fentanyl morphine Sponsor: Sarah Beckley Completed Tue, 18 Apr 2017 12:00:00 EDT A Multicentre Study to Evaluate the Safety and Efficacy of AD 923 in Comparison to MSIR for the Treatment of CBP in SubjectsConditions: Cancer; PainIntervention: Drug: AD 923 Sponsor: Sosei Terminated Thu, 13 Mar 2008 12:00:00 EDT Pilot Study for Testing Safety of Repetitive Magnetic Stimulation for Treatment of Dry EyeConditions: Dry Eye; Sjogren's Syndrome; Aqueous Tear Deficiency; Meibomian Gland Dysfunction; Dry Eye SyndromesIntervention: Device: Ocular Repetitive Magnetic Stimulation (RMS) treatment Sponsor: Epitech Mag Ltd. Completed Fri, 06 Jan 2017 12:00:00 EST
Peri-Incisional Drug Injection in Lumbar Spine SurgeryConditions: Lumbar Disc Herniation; Degenerative Disc Disease; SpondylolisthesisInterventions: Drug: Morphine; Drug: Epinephrine; Drug: naropin Sponsor: University of Minnesota Recruiting Tue, 01 May 2018 12:00:00 EDT Pilot Study of the Efficacy and Safety of Q8003 in Patients Who Have Undergone Total Knee Arthroplasty or Total Hip ArthroplastyCondition: Postoperative PainInterventions: Drug: Q8003 (morphine sulfate and oxycodone hydrochloride); Drug: Low dose Q8003 (morphine sulfate and oxycodone hydrochloride); Drug: Percocet (oxycodone and acetaminophen) Sponsor: QRxPharma Inc. Completed Wed, 07 Jan 2009 12:00:00 EST CTPVB for HepatectomyConditions: Pain Management; Paravertebral Block; HepatectomyInterventions: Procedure: Continuous Paravertebral block with ropivacaine; Procedure: Continuous Paravertebral "block" with saline; Drug: Patient-controlled analgesia with morphine Sponsor: Cui Xulei Completed Wed, 19 Jun 2019 12:00:00 EDT Different Lipid Soluble Opioids for Gynecologic Laparoscopic Surgery Postoperative Patient-controlled AnalgesiaCondition: Post Operative Pain ManagementInterventions: Drug: Sufentanil (R30730, brand name Sufenta); Drug: Sufentanil (R30730, brand name Sufenta) + Morphine; Drug: Morphine Sponsor: Peking University First Hospital Completed Tue, 06 Aug 2013 12:00:00 EDT Programmed Intermittent Bolus Infusion of Thoracic Paravertebral Block for HepatectomyConditions: Paravertebral Block; Hepatectomy; Analgesia; Postoperative RecoveryInterventions: Procedure: Paravertebral block-ropivacaine; Procedure: Paravertebral block-saline; Drug: patient controlled analgesia with morphine Sponsor: Cui Xulei Recruiting Wed, 11 Mar 2020 12:00:00 EDT Post-operative Pain Relief in Laparoscopic CholecystectomyCondition: Postoperative PainInterventions: Drug: bupivacaine; Drug: morphine; Drug: fentanyl; Drug: Ketamine: Sponsor: Assiut University Unknown status Tue, 28 Nov 2017 12:00:00 EST Transversus Abdominus Plane Block in Living Donor HepatectomyCondition: Living Donor HepatectomyInterventions: Device: surgically inserted Transversus abdominus plane catheter; Drug: Intravenous morphine; Drug: Bupevecaine; Drug: Dexmedetomedine Sponsor: AlRefaey Kandeel Completed Tue, 15 Mar 2016 12:00:00 EDT Total Knee Arthroplasty Analgesia: Single-shot Femoral Nerve Block or Epidural?Condition: Postoperative Pain Treatment for Total Knee ArthroplastyInterventions: Drug: Ropivacaine perineural injection; Drug: morphine and ropivacaine Sponsor: Centro Hospitalar do Tâmega e Sousa Completed Tue, 17 Jun 2014 12:00:00 EDT Comparison Between Low-dose Ketamine Infusion and Intravenous MorphineCondition: KetamineInterventions: Drug: Ketamine group:; Drug: Control group Sponsor: Cairo University Completed Mon, 24 Feb 2020 12:00:00 EST Dexmedetomidine Addition to Morphine in Patients With Metastatic CancerConditions: Refractory Pain; Metastatic CancerIntervention: Drug: Dexmedetomidine Sponsor: Hotel Dieu de France Hospital Completed Fri, 03 May 2019 12:00:00 EDT
Influence of Patient Choice of Intrathecal Morphine on Post-cesarean Delivery Pain.Condition: PainIntervention: Other: Drug Dose Sponsor: Stanford University Completed Tue, 30 Aug 2011 12:00:00 EDT Patient-Driven Analgesic Protocol Selection for Post-Cesarean Pain ManagementCondition: Postoperative PainInterventions: Other: No choice given; Other: Choice given; Drug: Ibuprofen; Drug: Acetaminophen; Drug: Gabapentin; Drug: Morphine (low); Drug: Morphine (med); Drug: Morphine (high) Sponsor: Stanford University Completed Mon, 16 Nov 2015 12:00:00 EST Comparison of the Efficacy and Safety of Q8003 Versus Its Individual Components in Bunionectomy PatientsCondition: Postoperative PainInterventions: Drug: Q8003; Drug: Morphine sulfate; Drug: Oxycodone HCl; Drug: Oxycodone HCl 4mg Sponsor: QRxPharma Inc. Completed Wed, 28 Jan 2009 12:00:00 EST Effect of Acute Arterial Hypertension on Morphine's Requirements and Postsurgical Pain.Conditions: Hypertensive Disease; Pain, PostoperativeInterventions: Other: SBP 20-30% over baseline; Other: SBP 20-30% under baseline Sponsor: Pontificia Universidad Catolica de Chile Completed Thu, 11 Jul 2013 12:00:00 EDT Evaluating the Relationship of Morphine Consumption and Pain-related Molecules in Hepatic Surgical PatientsConditions: Pain; Huntington Disease; Hepatic SurgeryIntervention: Sponsor: National Cheng-Kung University Hospital Completed Thu, 08 Aug 2013 12:00:00 EDT Effect of Pregabalin on Post Operative Pain in Abdominal Hysterectomy Under Spinal Anesthesia With Intrathecal MorphineCondition: Post Operative PainInterventions: Drug: placebo; Drug: Pregabalin Sponsor: Mahidol University Completed Thu, 06 Nov 2014 12:00:00 EST Safety and Pharmacokinetic Study of EMBEDA in Children Ages 7-17 With PainCondition: Moderate-severe PainInterventions: Drug: Ages 7-11; Drug: ages 12-17 Sponsor: Pfizer Terminated Wed, 02 Apr 2014 12:00:00 EDT Dexamethasone for Post Cesarean Delivery AnalgesiaCondition: Postoperative PainInterventions: Drug: Dexamethasone; Drug: Placebo Sponsor: University of Iowa Completed Tue, 04 Jun 2013 12:00:00 EDT The Effects of TAP Block on Postsurgical Pain After Minimally Invasive Partial Nephrectomy:Conditions: Acute Pain; Chronic PainInterventions: Procedure: Tap block; Procedure: intravenous Patient controlled analgesia; Drug: Morphine; Drug: Ropivacaine Sponsor: Regina Elena Cancer Institute Completed Tue, 02 Jun 2015 12:00:00 EDT Femoral Nerve Block Compared to Exparel in Total Knee ReplacementConditions: Osteoarthritis; PainInterventions: Drug: Exparel; Drug: Femoral Nerve Block Bupivacaine; Drug: Toradol; Drug: Morphine Sulfate Sponsor: The New England Baptist Hospital Unknown status Tue, 16 Jun 2015 12:00:00 EDT
Efficacy of the Ultrasound-guided Transversus Abdominis Plane Block in Open Aortic Abdominal Aneurysm Repair SurgeryConditions: Aortic Aneurysm, Abdominal; Pain; Anesthesia, LocalInterventions: Procedure: TAP block; Drug: PCA with Chlorhydrate of Morphine; Drug: Acetaminophen Sponsor: Centre Hospitalier Universitaire de Besancon Unknown status Mon, 17 Nov 2014 12:00:00 EST International Prospective Study on Morphine-induced Adverse Drug Reactions in Emergency Departments.Condition: EmergenciesIntervention: Sponsor: University Hospital, Toulouse Completed Tue, 31 Jul 2012 12:00:00 EDT Analgesic Efficacy of Morphine Alone or Combined With Paracetamol and/or Ibuprofen for Long-bones Fractures in ChildrenConditions: Pain; Long-bone FracturesInterventions: Drug: Paracetamol; Drug: Ibuprofen; Drug: paracetamol + ibuprofen; Drug: Placebo Sponsor: Assistance Publique - Hôpitaux de Paris Completed Mon, 22 Jun 2015 12:00:00 EDT Efficacy of Peri-Incisional Multimodal Drug Injection Following Operative Management of Femur FracturesConditions: Pain, Postoperative; Femur FractureInterventions: Drug: Ropivacaine; Drug: Epinephrine; Drug: Morphine; Drug: 0.9% sodium chloride solution Sponsor: University of Iowa Completed Wed, 08 Jun 2016 12:00:00 EDT Mechanisms of Sleep Disruption HyperalgesiaConditions: Sleep Deprivation; PainInterventions: Drug: Morphine; Drug: Saline Placebo; Behavioral: Forced Awakenings; Behavioral: Uninterrupted Sleep Sponsors: Johns Hopkins University; National Institute on Drug Abuse (NIDA) Completed Wed, 20 Feb 2013 12:00:00 EST A Study to Evaluate the Abuse Potential of Oxymorphone Compared to Other Mu Opioid Agonists.Conditions: Opioid-use Disorder; Opioid AbuseIntervention: Drug: Intravenous Challege Drug Sponsors: New York State Psychiatric Institute; University of Kentucky Recruiting Thu, 04 Jan 2018 12:00:00 EST Prospective Study of Pain After Spinal Morphine for Cesarean Section and Factors Involved in Moderate to Severe PainCondition: Pain, PostoperativeIntervention: Sponsor: Mahidol University Completed Sun, 02 Jul 2017 12:00:00 EDT Effect of Guanfacine on Opioid-induced Hyperalgesia (OIH) and ToleranceCondition: Chronic PainInterventions: Drug: Morphine; Drug: Guanfacine 1mg; Drug: Guanfacine 2mg; Drug: Placebo Sponsors: Massachusetts General Hospital; National Institutes of Health (NIH); National Institute on Drug Abuse (NIDA) Active, not recruiting Fri, 07 Sep 2012 12:00:00 EDT Postoperative Pain, Recovery and Discharge Following Robot-assisted Laparoscopic ProstatectomyConditions: Radical Prostatectomy; Postoperative PainInterventions: Drug: Bupivacaine; Drug: Analgesics Sponsor: Karolinska Institutet Recruiting Tue, 21 Aug 2018 12:00:00 EDT A Comparison of the Post-C/S Analgesic Effects of Neuraxial Duramorph vs Bilateral TAP Block With Liposomal BupivacaineCondition: Caesarean SectionIntervention: Drug: Exparel Sponsor: Maimonides Medical Center Terminated Mon, 20 Aug 2018 12:00:00 EDT
Study of Intensive, Home-Based Family Therapy to Improve Illness Management in Youth With DiabetesCondition: Diabetes Mellitus, Insulin DependentInterventions: Behavioral: Intensive Home-Based Family Therapy; Behavioral: Supportive Telephone Calls Sponsors: Wayne State University; National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Completed Thu, 07 Sep 2006 12:00:00 EDT Effect of Paracetamol and Ibuprofen Reducing Morphine Requirements After Total Knee ArthroplastyCondition: AnalgesiaInterventions: Drug: Paracetamol injection and Ibuprofen injection; Drug: Paracetamol injection and normal saline; Drug: Ibuprofen Injection and normal saline Sponsor: Indonesia University Completed Thu, 04 Jun 2020 12:00:00 EDT Benefits of Opioid Free Anesthesia on Morphine Consumption in Gastric BypassCondition: Analgesics, OpioidInterventions: Drug: Dexmedetomidine Injection [Precedex]; Drug: Remifentanil Sponsor: matthieu clanet Recruiting Fri, 13 Aug 2021 12:00:00 EDT Continuous Infusion of Dexamethasone Plus Tramadol Adjunct to Morphine PCA After Abdominal HysterectomyConditions: Postoperative Pain; Post Operative Analgesia; Patient-Controlled Analgesia; Abdominal SurgeriesInterventions: Drug: Dexamethasone Sodium Phosphate Injection; Other: 0.9% Saline Sponsors: Nanjing Medical University; HRSA/Maternal and Child Health Bureau Completed Wed, 28 Nov 2007 12:00:00 EST Intraoperative and Postoperative Analgesia for Laparoscopic Surgery.Condition: AnalgesiaInterventions: Drug: morphine; Drug: intrathecal analgesia (morphine); Drug: general anesthesia (fentanyl) Sponsor: Rambam Health Care Campus Completed Wed, 15 Oct 2008 12:00:00 EDT Local Anesthetic Treatment of Oral Pain in Patients With MucositisCondition: MucositisInterventions: Drug: Bupivacaine; Drug: Standard treatment (lidocaine viscous solution, morphine, paracetamol, NSAID, gabapentin) Sponsors: Hvidovre University Hospital; Moberg Pharma, Sweden Completed Tue, 30 Sep 2014 12:00:00 EDT Ibuprofen or Morphine in Treating Pain in Patients Undergoing Pleurodesis for Malignant Pleural EffusionCondition: Metastatic CancerInterventions: Drug: ibuprofen; Drug: morphine sulfate; Procedure: management of therapy complications; Procedure: pleurodesis Sponsor: Oxford University Hospitals NHS Trust Unknown status Wed, 26 Mar 2008 12:00:00 EDT Postoperative Analgesia in Abdominal Surgery: a Medico-economic StudyConditions: Extended Ileal Resection Under Laparotomy; Total Proctocolectomy Under Laparotomy; Colectomy Left/Right/Total Under Laparotomy; Rectosigmoidal Resection Under Laparotomy; Anterior Resection of Rectum Under Laparotomy; Abdomino-perineal Amputation Under LaparotomyInterventions: Procedure: epidural analgesia; Procedure: PCA Sponsor: University Hospital, Limoges Terminated Fri, 11 Nov 2011 12:00:00 EST Morphine-sparing Effect of Intravenous Paracetamol for Post-operative Pain Management Following Laparoscopic Gastric Banding in Morbidly Obese PatientsCondition: ObesityInterventions: Drug: Paracetamol; Drug: Placebo Sponsor: Soroka University Medical Center Unknown status Tue, 03 Jun 2014 12:00:00 EDT Study To Compare Single Dose Of Three Modified Release Formulations Of PF-04937319 With Immediate Release Material-Sparing-Tablet (IR MST) Formulation Previously Studied In Adults With Type 2 Diabetes Mellitus.Condition: Type 2 Diabetes MellitusInterventions: Drug: PF-04937319 IR MST; Drug: PF-04937319 MR 1; Drug: PF-04937319 MR 2; Drug: PF-04937319 MR 3 Sponsor: Pfizer Completed Fri, 01 Aug 2014 12:00:00 EDT
Open Radical Prostatectomy and Erector Spinae Plane BlockConditions: Prostate Cancer; Anesthesia, Local; Pain, PostoperativeInterventions: Procedure: Single-injection ultrasound-guided bilateral erector spinae plane (ESP) block-Sham; Procedure: Single-injection ultrasound-guided bilateral erector spinae plane block-Lidocaine/Bupivacaine; Other: Pain follow-up and monitorization Sponsors: BURHAN DOST; Ondokuz Mayıs University Completed Tue, 07 Apr 2020 12:00:00 EDT The Effect of Chlorzoxazone on Moderate to Severe Postoperative Pain After Spine SurgeryConditions: Chlorzoxazone; Postoperative PainInterventions: Drug: Placebo; Drug: Chlorzoxazone; Drug: Morphine; Drug: Zofran Sponsors: Rigshospitalet, Denmark; Glostrup University Hospital, Copenhagen Completed Mon, 02 Sep 2013 12:00:00 EDT Methadone in Ambulatory SurgeryConditions: Post-operative Pain; AnesthesiaInterventions: Drug: methadone; Drug: Control (Intra-operative administration of opioids, other than methadone) Sponsor: Washington University School of Medicine Completed Mon, 24 Nov 2014 12:00:00 EST Preemptive Oral Gabapentin 600 mg in Reducing Morphine Requirement After Non Obstetric Lower Abdominal SurgeryCondition: Non-obstetric Lower Abdominal SurgeryInterventions: Drug: Gabapentin; Other: Placebo Sponsor: Indonesia University Completed Tue, 16 Jun 2020 12:00:00 EDT Analgesic Efficacy of Transmuscular Quadratus Lumborum in Patients Undergoing Total Abdominal HysterectomyCondition: Pain PostoperativeInterventions: Procedure: Transmuscular quadratus lumborum block; Drug: morphine; Drug: ropivacaine Sponsor: Kuala Lumpur General Hospital Completed Mon, 26 Oct 2015 12:00:00 EDT Opioid/Benzodiazepine Polydrug Abuse: Aim 3Conditions: Opioid Abuse; Benzodiazepine Abuse; Polysubstance AbuseInterventions: Drug: Morphine; Drug: Alprazolam; Drug: Placebo Sponsors: Wayne State University; Henry Ford Health System Not yet recruiting Mon, 16 Aug 2021 12:00:00 EDT Comparison of Three Opioid Detoxification Treatment RegimensConditions: Opioid-Related Disorders; Opioid WithdrawalInterventions: Drug: Buprenorphine/naloxone; Drug: Morphine; Drug: Tramadol Sponsor: University of Alabama at Birmingham Withdrawn Thu, 20 Sep 2018 12:00:00 EDT RCT of Epinephrine (None, 100mcg, and 200mcg) in a Hyperbaric Bupivacaine, Fentanyl and Morphine Spinal in C-sections.Conditions: Pregnancy; Cesarean SectionInterventions: Drug: 100 mcg Epinephrine; Other: normal saline; Drug: 200 mcg Epinephrine Sponsor: University of Florida Withdrawn Tue, 07 Nov 2017 12:00:00 EST Erector Spinae Plane Block for Rib Fracture Analgesia in the Emergency DepartmentCondition: Rib Fracture MultipleInterventions: Procedure: Erector Spinae Plane Block; Drug: IV Analgesia Sponsor: University of Southern California Not yet recruiting Wed, 19 May 2021 12:00:00 EDT Transcultural Validation of MSTS and TESS QuestionnaireCondition: CancerIntervention: Sponsors: Nantes University Hospital; University Hospital, Angers Unknown status Wed, 05 Dec 2018 12:00:00 EST
MST in Patients With Inflammatory Rheumatic DiseaseCondition: Inflammatory RheumatismIntervention: Behavioral: Maximal strength training Sponsor: Molde University College Completed Tue, 10 Aug 2021 12:00:00 EDT A Study to Asses Efficacy, Safety and Tolerability of Monthly Long-acting IM Injection of GA Depot in Subjects With RMSCondition: Multiple Sclerosis, Relapsing-RemittingInterventions: Drug: GA Depot; Other: Placebo Sponsor: Mapi Pharma Ltd. Active, not recruiting Wed, 09 Oct 2019 12:00:00 EDT IV PCA With or Without Continuous Dose vs Oral Opioid to Maintain Analgesia for Severe Cancer Pain After Successful TitrationCondition: Cancer PainInterventions: Drug: Hydromorphone Hydrochloride Injection; Drug: Morphine Sulfate Sustained-release Tablets Sponsor: Fujian Cancer Hospital Not yet recruiting Mon, 08 Mar 2021 12:00:00 EST Double Blind Efficacy and Safety Study of Flexible-Dose vs Low-Dose Q8003 After Undergoing Primary Unilateral Total Knee ArthroplastyCondition: Postoperative PainInterventions: Drug: Flexible dose Q8003 (morphine sulfate and oxycodone hydrochloride); Drug: Low dose Q8003 (morphine sulfate and oxycodone hydrochloride) Sponsor: QRxPharma Inc. Completed Mon, 25 Jan 2010 12:00:00 EST Gabapentin for Prophylaxis Intrathecal Morphine-Induced PruritusCondition: PruritusIntervention: Drug: Gabapentin Sponsor: Prince of Songkla University Completed Tue, 09 Nov 2010 12:00:00 EST Effects of Epidural Lidocaine on the Pharmacokinetic and Pharmacodynamic Profiles of DepoDur® After Cesarean DeliveryCondition: Epidural Analgesia, ObstetricInterventions: Drug: DepoDur following epidural lidocaine; Drug: DepoDur following spinal anesthetic Sponsor: Stanford University Completed Tue, 09 Dec 2008 12:00:00 EST Efficacy of Multimodal Periarticular Injections in Operatively Treated Ankle FracturesConditions: Pain, Postoperative; Ankle FracturesInterventions: Drug: Ropivacaine; Drug: Epinephrine; Drug: Morphine; Drug: 0.9% sodium chloride solution Sponsor: Kyle Hancock Completed Fri, 18 Nov 2016 12:00:00 EST Mechanisms of Hypoglycemia Associated Autonomic FailureConditions: Diabetes Mellitus; Hypoglycemia; Autonomic FailureInterventions: Drug: naloxone; Dietary Supplement: fructose; Behavioral: exercise; Drug: Morphine sulfate; Drug: Epinephrine Sponsors: Albert Einstein College of Medicine; National Institutes of Health (NIH); National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Active, not recruiting Thu, 15 May 2008 12:00:00 EDT Patient Controlled Analgesia Pump Cues on Patient SatisfactionCondition: Postoperative PainInterventions: Device: Patient-Controlled Analgesia pump with Cues; Device: Patient-Controlled Analgesia pump without Cues; Drug: Morphine Sponsors: Medical College of Wisconsin; Children's Hospital and Health System Foundation, Wisconsin Completed Fri, 29 May 2015 12:00:00 EDT Estimation of the Effective Dose (ED) 95 of Intrathecal Hyperbaric Prilocaine 2% for Scheduled Cesarean Delivery.Condition: Pregnant WomenInterventions: Drug: Hyperbaric prilocaine 2%; Drug: Morphine Sponsor: Centre Hospitalier Universitaire Saint Pierre Completed Tue, 31 Jul 2018 12:00:00 EDT
Continuous Local Anesthetic and Steroid Infusion in Abdominal SurgeryCondition: Abdominal PainInterventions: Drug: ropivacaine 0.2%; Drug: Methylprednisolone 1mg/kg; Drug: saline 0.9% Sponsor: IRCCS Policlinico S. Matteo Completed Fri, 06 Dec 2013 12:00:00 EST Automated urIne Flow Detection to Reduce Errors and Nursing WorkloadConditions: Acute Kidney Injury; Kidney InjuryIntervention: Device: Clarity RMS Electronic Sensor Sponsors: University of Pittsburgh; RenalSense Ltd Completed Fri, 17 Aug 2018 12:00:00 EDT Atropine to Prevent Nausea and Vomiting After Spinal Anesthesia for Caesarean SectionConditions: Cesarean Section; Anesthesia,Spinal; Postoperative Nausea and VomitingInterventions: Drug: Bupivacaine; Drug: Morphine; Drug: Isotonic saline solution; Drug: Atropine Sponsor: University of Parma Completed Tue, 16 Jun 2009 12:00:00 EDT A PhaseⅡ/ Ⅲ Seamless Study to Evaluate Efficacy and Safety of Paracetamol Injection as Adjuvant to Morphine-based Postoperative AnalgesiaCondition: Post-operative AnalgesiaInterventions: Drug: Paracetamol injection; Drug: Normal Saline injection; Drug: Morhpine PCA Sponsor: Jiangsu HengRui Medicine Co., Ltd. Completed Thu, 23 Jun 2016 12:00:00 EDT Implications of Different Analgesic Models on Inflammatory Markers After Laparoscopic CholecystectomyCondition: Perioperative PainInterventions: Drug: Bupivacaine; Drug: isotonic saline; Drug: Bupivacaine + morphine; Drug: Bupivacaine + morphine + ketamine Sponsor: Assiut University Completed Fri, 30 Oct 2020 12:00:00 EDT Morphine Gel for BedsoresCondition: Decubitus UlcerIntervention: Drug: Pain relief for pressure ulcers Sponsors: University of Kansas; National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) Completed Mon, 18 Dec 2000 12:00:00 EST Controlled-Release Oxycodone For Postoperative Analgesia After Video-Assisted Thoracic SurgeryConditions: Anesthesia Recovery Period; Pain, PostoperativeInterventions: Drug: Morphine; Drug: oxycodone; Procedure: Paravertebral block; Drug: Propofol; Drug: Remifentanil; Drug: Paracetamol Sponsor: University of Parma Terminated Wed, 21 May 2008 12:00:00 EDT Prevention of Intrathecal Morphine Induced Pruritus: Comparison of Ondansetron and PalonosetronCondition: Morphine Adverse ReactionInterventions: Drug: Ondansetron; Drug: Palonosetron Sponsor: Kyungpook National University Hospital Completed Mon, 30 Sep 2013 12:00:00 EDT Study of Oliceridine (TRV130) for the Treatment of Moderate to Severe Acute Pain After BunionectomyCondition: Acute PainInterventions: Drug: Oliceridine; Drug: Placebo; Drug: Morphine Sponsor: Trevena Inc. Completed Tue, 28 Jun 2016 12:00:00 EDT Efficacy of Prevention for Postoperative Nausea and Vomiting After Intrathecal Morphine in Cesarean SectionConditions: Pregnancy; PONVInterventions: Drug: dexamethasone; Drug: dexamethasone 5 mg Sponsor: Mahidol University Unknown status Tue, 05 May 2009 12:00:00 EDT
Outpatient Adolescent Treatment for Comorbid Substance Use and Internalizing DisordersConditions: Substance-Related Disorders; Depressive Disorder; Anxiety DisorderInterventions: Behavioral: Outpatient MST/OPTION-A; Behavioral: Usual Services Sponsors: Medical University of South Carolina; National Institute on Drug Abuse (NIDA) Completed Thu, 22 Feb 2007 12:00:00 EST Evaluation of the Tolerability of Switching Subjects on Chronic ATC Opioid Therapy to Buprenorphine HCl Buccal FilmCondition: PainInterventions: Drug: Buprenorphine; Drug: Placebo film; Drug: Oxycodone; Drug: Morphine sulfate; Drug: Placebo capsule Sponsor: BioDelivery Sciences International Completed Thu, 06 Jun 2013 12:00:00 EDT Ondansetron vs Ondansetron Plus Dexamethasone for Relieving Intrathecal Morphine Side Effects After C-sectionConditions: Pruritus; Cesarean SectionInterventions: Drug: Ondansetron (Zofran); Drug: Dexamethasone (Decadron); Other: Spinal anesthesia Sponsor: Makassed General Hospital Completed Wed, 08 Jun 2016 12:00:00 EDT Study of Oliceridine (TRV130) for the Treatment of Moderate to Severe Acute Pain After AbdominoplastyCondition: Acute PainInterventions: Drug: Oliceridine; Drug: Placebo; Drug: Morphine Sponsor: Trevena Inc. Completed Thu, 30 Jun 2016 12:00:00 EDT Determinants of Oral Morphine Answer Among Obese Patients Before and After Gastric BypassCondition: ObesityIntervention: Procedure: gastric bypass Sponsor: Hopital Lariboisière Completed Wed, 22 Jul 2009 12:00:00 EDT Comparison of Erector Spinae Plane Block With Thoracic Paravertebral Block for Breast SurgeryConditions: Postoperative Pain; Breast CancerInterventions: Device: Intravenous morphine patient controlled device; Other: Erector Spinae Plane Block; Other: Thoracic Paravertebral Block Sponsor: Kocaeli University Completed Thu, 29 Mar 2018 12:00:00 EDT The Effect of the Transversus Abdominis Plane Block to Postoperative Analgesia for Cesarean SectionCondition: Obstetric PainInterventions: Procedure: TAP block; Drug: Morphine; Drug: Ropivacaine Sponsor: Gia Dinh People Hospital Completed Thu, 16 Aug 2018 12:00:00 EDT Postoperative Epidural Analgesia in Spine Fusion SurgeryCondition: PainInterventions: Drug: 0.125% Bupivacaine HCL @ 4-5 ml/h; Drug: 0.125% Bupivacaine HCL , Morphine sulphate @ 3 mg 3-5 ml/h; Drug: 0.125% Bupivacaine, Fentanyl 100 mic @ 3-5 ml/h Sponsor: Assiut University Completed Wed, 24 Apr 2013 12:00:00 EDT Study of Efficacy and Safety of Fingolimod (Gilenya) 0.5 mg in Chinese Patients With Relapsing Multiple Sclerosis (RMS) PatientsCondition: Relapsing Multiple Sclerosis (RMS)Intervention: Drug: Fingolimod 0.5mg Sponsor: Novartis Pharmaceuticals Recruiting Wed, 16 Dec 2020 12:00:00 EST Study on Impact of Maximal Strength Training in Patients With COPDCondition: Chronic Obstructive Pulmonary DiseaseInterventions: Other: Maximal strenght training (MST) plus endurance training (ET); Other: Endurance training (ET) Sponsors: Istituti Clinici Scientifici Maugeri SpA; Universita di Verona Recruiting Thu, 10 Jan 2019 12:00:00 EST
Bilateral vs. Unilateral Erector Spinae Plane BlockConditions: Postoperative Pain; Cholecystitis; GallstoneInterventions: Procedure: Bilateral ESP Block; Procedure: Unilateral ESP Block; Device: Intravenous Morphine patient controlled analgesia device Sponsor: Kocaeli University Completed Thu, 20 Dec 2018 12:00:00 EST Aromatherapy for Prevention of Intrathecal Morphine Induced Nausea and VomitingCondition: Post Operative Nausea and VomitingInterventions: Biological: Peppermint essential oil; Drug: Granisetron; Drug: Dexamethasone Sponsor: Universiti Kebangsaan Malaysia Medical Centre Completed Thu, 15 Feb 2018 12:00:00 EST Metabolites of Tramadol in the Postoperative Surgical PatientsConditions: Abdominal Surgery; Respiratory Failure; Renal Failure; Liver Dysfunction; Multiorgan FailureIntervention: Drug: Postoperative analgesia using tramadol Sponsors: Osijek University Hospital; Josip Juraj Strossmayer University of Osijek Completed Tue, 02 Jul 2019 12:00:00 EDT Surgicel and Analgesic ReservoirCondition: Postoperative PainInterventions: Drug: "Local Anesthetic", "Epinephrine" and "Morphine"; Drug: "Local Anesthetic", "Epinephrine", "Morphine" and "Surgicel"; Drug: "Normal Saline" Sponsor: Assiut University Completed Mon, 05 Nov 2018 12:00:00 EST The Match Study in ESRD PatientsCondition: Dialysis Access MalfunctionIntervention: Device: Alio Medical Remote Monitoring System (RMS) Sponsor: Alio Medical Not yet recruiting Mon, 07 Jun 2021 12:00:00 EDT 10% Carbohydrate Drink for Preventing Post-operative Nausea and Vomiting (PONV) After Spinal MorphineCondition: Nausea and Vomiting, PostoperativeIntervention: Dietary Supplement: 10% carbohydrate drink Sponsor: Mahidol University Completed Wed, 23 Feb 2011 12:00:00 EST Analgesia and Pancreatic Cancer SurgeryCondition: Pancreatic NeoplasmsInterventions: Procedure: Epidural patient controlled analgesia; Drug: Intravenous patient controlled analgesia Sponsor: National Taiwan University Hospital Unknown status Wed, 28 Aug 2013 12:00:00 EDT Oral Oxycodone After Major Cardiac SurgeryCondition: Heart; Dysfunction Postoperative, Cardiac SurgeryInterventions: Drug: Targin; Drug: Oxynorm; Drug: Morphine Sponsor: Medical University of Vienna Completed Fri, 22 Mar 2013 12:00:00 EDT Quality of Recovery After Dexamethasone, Ondansetron or Placebo Intrathecal Morphine AdministrationConditions: Fractures, Bone; Nausea and Vomiting, Postoperative; Pruritus; Morphine Adverse Reaction; Satisfaction, PersonalInterventions: Drug: Dexamethasone; Drug: Ondansetron; Drug: Saline Sponsor: Pontificia Universidade Catolica de Sao Paulo Completed Mon, 30 Jan 2017 12:00:00 EST Clinical Effectiveness of Erector Spinae Plane Block in Peri-operative Analgesia for Laparoscopic Nephrectomy/Nephron Sparing Surgery (NSS)/Hynes-Anderson Procedures.Condition: Erector Spinae Plane BlockInterventions: Procedure: bilateral ESP block with 0,25% Bupivacaine+ Adrenaline; Procedure: ESP block continuous infusion with 0,125% Bupivacaine+Adrenaline; Drug: Morphine PCA pump Sponsor: Medical University of Warsaw Recruiting Thu, 14 Mar 2019 12:00:00 EDT
Morphine Consumption in ThoracotomyCondition: Postoperative PainInterventions: Procedure: PVB; Procedure: ESPB Sponsor: Kocaeli University Recruiting Tue, 10 Aug 2021 12:00:00 EDT Initial Pain Management in Pediatric Pancreatitis: Opioid vs. Non-OpioidCondition: Acute PancreatitisInterventions: Drug: Ketorolac; Drug: Opioid Sponsors: Boston Children's Hospital; The National Pancreas Foundation Not yet recruiting Mon, 02 Mar 2020 12:00:00 EST Buprenorphine's Dose Response CurveCondition: Opioid-related DisordersInterventions: Drug: Buprenorphine; Drug: Morphine; Drug: Placebo Sponsors: Johns Hopkins University; National Institute on Drug Abuse (NIDA) Completed Fri, 13 Apr 2007 12:00:00 EDT Evaluation of the Use of Spinal Epimorph in Total Knee ArthroplastyConditions: Post-operative Pain; OsteoarthritisInterventions: Drug: Epimorph; Drug: Spinal analgesia Sponsor: Lawson Health Research Institute Completed Fri, 17 Aug 2012 12:00:00 EDT Postoperative Belladonna and Morphine Suppositories in Vaginal SurgeryCondition: Vaginal SurgeryInterventions: Drug: Belladonna and Opium Suppositories; Drug: Placebo Suppositories Sponsor: Kristina A. Butler Completed Fri, 25 Jun 2010 12:00:00 EDT Open Label Randomized Multicenter to Assess Efficacy & Tolerability of Ofatumumab 20mg vs. First Line DMT in RMSCondition: Multiple SclerosisInterventions: Drug: Ofatumumab; Drug: First line DMT Sponsor: Novartis Pharmaceuticals Recruiting Tue, 09 Mar 2021 12:00:00 EST Intrathecal Morphine Microdose Method Sensory ChangesConditions: Analgesic Drug Dependence; Sensory Disorders; Chronic PainInterventions: Behavioral: Quantitative Sensory Tests; Behavioral: surveys Sponsor: The University of Texas Medical Branch, Galveston Recruiting Wed, 10 Jan 2018 12:00:00 EST Pharmacogenetic Morphine Spine StudyCondition: PainIntervention: Sponsor: Children's Hospital Medical Center, Cincinnati Completed Wed, 24 Apr 2013 12:00:00 EDT Effects of Osteoarthritis Pain, Morphine, and Placebo on Neuroendocrine Function in MenCondition: OsteoarthritisIntervention: Procedure: Blood Draw Sponsor: National Center for Complementary and Integrative Health (NCCIH) Completed Mon, 26 Jul 2004 12:00:00 EDT Effect of Epidural Anesthesia and Analgesia on Quality of Recovery After Radical Prostatectomy.Conditions: Anesthesia; Anesthesia Recovery Period; Radical Prostatectomy; Patient Satisfaction; Postoperative Period; Quality of Life; Analgesia; Epidural; Quality of RecoveryInterventions: Procedure: Epidural anesthesia with light general anesthesia; Drug: Postoperative epidural analgesia; Procedure: General anesthesia; Drug: Continuous intravenous analgesia Sponsor: University Hospital of Split Completed Wed, 14 Oct 2020 12:00:00 EDT
Multimodal Analgesia Strategies After Major Shoulder Ambulatory SurgeryCondition: Tendon InjuriesInterventions: Drug: Tramadol; Drug: Nefopam 20 MG/ML; Drug: Morphine Sulfate; Drug: Oxycodone 20mg Sponsor: Centre Hospitalier Universitaire de Nīmes Unknown status Tue, 01 Oct 2019 12:00:00 EDT Effect of Epidural Anesthesia and Analgesia on Quality of Recovery After Unilateral Nephrectomy.Conditions: Anesthesia; Anesthesia Recovery Period; Nephrectomy; Patient Satisfaction; Postoperative Period; Quality of Life; Analgesia; EpiduralInterventions: Procedure: Epidural anesthesia with light general anesthesia; Procedure: Postoperative epidural analgesia; Procedure: General anesthesia; Drug: Continuous intravenous analgesia Sponsor: University Hospital of Split Completed Thu, 20 Aug 2020 12:00:00 EDT Ultrasound Guided Single Shot Block of Posterior Tibial Nerve for Postoperative Pain Relief After Hallux Valgus SurgeryCondition: Hallux ValgusInterventions: Drug: Ropivacaine 0,75%; Procedure: posterior tibial nerve block; Drug: morphine and droperidol Sponsor: Dr.med. Sabine Schoenfeld Unknown status Wed, 05 Nov 2014 12:00:00 EST Effect of Dexmedetomidine on Postoperative Glucose and Insulin Levels.Conditions: Bariatric Surgery Candidate; Glucose Intolerance; Insulin ResistanceInterventions: Drug: Dexmedetomidine; Drug: 0.9% Sodium-chloride; Drug: Fentanyl; Drug: Morphine Sulfate Sponsor: Pontificia Universidad Catolica de Chile Completed Fri, 18 Jan 2019 12:00:00 EST Electro-Magnetic Convulsive Therapies for Depression: a Non-inferiority StudyConditions: Major Depressive Disorder; Bipolar DepressionInterventions: Device: Magnetic Seizure Therapy; Device: Electroconvulsive Therapy Sponsors: University of Sao Paulo; Fundação de Amparo à Pesquisa do Estado de São Paulo Recruiting Thu, 23 Sep 2021 12:00:00 EDT Paravertebral Analgesia Associated With Intravenous Morphine PCA After ThoracotomyCondition: PainInterventions: Drug: ropivacaine; Other: nacl 0,9% Sponsor: University Hospital, Strasbourg, France Completed Thu, 21 Feb 2008 12:00:00 EST The Effect of Intraoperative Ketamine on Opioid Consumption and Pain After Spine Surgery in Opioid-dependent PatientsConditions: Postoperative Pain; Chronic Pain; AnalgesicsInterventions: Drug: (S)-(+)-Ketamine Hydrochloride Solution 25 mg/ml; Drug: Isotonic sodium chloride 0.9 percent; Drug: Paracetamol 1 g; Drug: Morphine Sulphate 1 mg/ml; Drug: Ondansetron 2 mg/ml; Drug: Usual daily opioids; Drug: Sufentanil 5 microgram/ml Sponsors: Rigshospitalet, Denmark; Glostrup University Hospital, Copenhagen Completed Thu, 13 Mar 2014 12:00:00 EDT Multimodal Opioid-free Anesthesia Versus Opioid-based Anesthesia for Patients Undergoing Cardiac Valve Surgeries: RCTCondition: AnesthesiaInterventions: Drug: Dexmedetomidine 0.5 mic/kg/h; Drug: Fentanyl 1 mic/kg/hr Sponsor: Cairo University Recruiting Tue, 01 Dec 2020 12:00:00 EST Multisystemic Therapy to Reduce Health Disparities in Adolescents With AsthmaCondition: AsthmaInterventions: Behavioral: Multisystemic Therapy; Behavioral: Home-based, Non-Directive Family Support Sponsor: National Heart, Lung, and Blood Institute (NHLBI) Completed Tue, 09 Jun 2009 12:00:00 EDT An Open-label Evaluation of Tapentadol Extended Release (ER) in Participants With Moderate to Severe Chronic Pain After Conversion From Hydrocodone, Oxycodone Controlled Release (CR), and/or Morphine Sustained Release (SR)Conditions: Pain; Chronic Back Pain; Chronic Low Back Pain; Osteoarthritis Pain In The Hip or KneeIntervention: Drug: Nucynta ER Sponsor: Janssen Scientific Affairs, LLC Withdrawn Fri, 29 Jun 2012 12:00:00 EDT
Erector Spinae Plane Block in Scoliotic AdolescentsConditions: Scoliosis Idiopathic; Scoliosis; Adolescence; Erector Spinae Plane BlockInterventions: Procedure: Erector Spinae Plane Block; Drug: Fentanyl; Drug: additional Fentanyl; Drug: Morphine; Drug: rescue Morphine; Drug: pethidine; Drug: Ketorolac; Drug: Acetaminophen Sponsor: Kasr El Aini Hospital Completed Thu, 30 May 2019 12:00:00 EDT A Pilot Study of the Use of Magnetic Seizure Therapy for DepressionCondition: Treatment Resistant DepressionIntervention: Device: MST Sponsor: Bayside Health Completed Tue, 16 Dec 2008 12:00:00 EST Hemodynamic Effects of Low Dose Spinal Anesthesia for Cesarean SectionConditions: Complications; Cesarean Section; Effects of; Anesthesia, Spinal and Epidural, in Pregnancy; Hemodynamic Instability; Personal SatisfactionInterventions: Drug: Bupivacaine 4.5; Drug: Bupivacaine 9; Drug: Morphine; Drug: Fentanyl Sponsor: University of Manitoba Terminated Wed, 15 Jan 2014 12:00:00 EST 24-hour Oral Morphine Equivalent Based Opioid Prescribing After SurgeryCondition: Opioid UseInterventions: Other: Arm 1 Prescription As Usual; Other: Arm 2 Prescription Tool Intervention Sponsors: University of Colorado, Denver; National Institute on Drug Abuse (NIDA) Completed Fri, 02 Aug 2019 12:00:00 EDT Predict MDE Outcomes After MSTCondition: Major Depressive EpisodeInterventions: Device: Magpro X100 + Option; Device: ThymatronSystem Ⅳ Electroconvulsive System Sponsor: Shanghai Mental Health Center Recruiting Fri, 15 Feb 2019 12:00:00 EST Dexmedetomidine to Treat Bariatric Surgery-associated PainCondition: ObesityInterventions: Drug: Fentanyl; Drug: Morphine; Drug: Dexmedetomidine Sponsor: Janelle Vaughns Completed Fri, 26 Aug 2016 12:00:00 EDT Ketamine Low dOse Evaluation on Morphine Consumption in Traumatic PatientCondition: Traumatic InjuryIntervention: Drug: Administration of drug Sponsor: Assistance Publique Hopitaux De Marseille Not yet recruiting Tue, 06 Apr 2021 12:00:00 EDT Subcutaneous Bupivacaine Decrease Post-op Pain in Patients Undergoing C-SectionCondition: Pain, ReferredInterventions: Drug: Bupivacaine; Drug: Morphine; Drug: Fentanyl; Drug: Epinephrine; Other: Saline solution Sponsor: Montefiore Medical Center Terminated Tue, 26 Dec 2017 12:00:00 EST Dexmedetomidine for Morphine Consumption Reduction (DEXDOR)Condition: BurningIntervention: Sponsor: Centre Hospitalier Régional Metz-Thionville Completed Mon, 19 Sep 2016 12:00:00 EDT Comparisons of iv Ibuprofen and iv Paracetamol During Bariatric SurgeryConditions: Bariatric Surgery Candidate; Obesity, MorbidInterventions: Drug: paracetamol; Drug: ibuprofen Sponsor: Inonu University Completed Fri, 20 May 2016 12:00:00 EDT
Analgetic and Anxiolytic Effect of Preoperative PregabalinConditions: Intervertebral Disk Displacement; Disk ProlapseInterventions: Drug: pregabalin; Drug: Placebo; Drug: morphine Sponsor: Asker & Baerum Hospital Completed Wed, 19 Jul 2006 12:00:00 EDT Herb Drug Interaction of Traditional Chinese Herb and Commonly Used DrugsCondition: HealthyInterventions: Drug: Nalbuphine; Drug: Morphine; Drug: Morphine with Long dan xie gan tang; Drug: Nalbuphine with Long dan xie gan tang; Drug: Nubian with Long dan xie gan tang Sponsor: Tri-Service General Hospital Unknown status Thu, 18 Jun 2009 12:00:00 EDT Postoperative Morphine Consumption After Caesarean Section- TAP Block vs Intracutaneous InfiltrationCondition: PregnancyInterventions: Procedure: TAP block; Procedure: control Sponsors: St. Olavs Hospital; Norwegian University of Science and Technology Completed Tue, 28 Aug 2012 12:00:00 EDT Effectiveness of New Analgesic Strategy Compared to the Usal Antalgic StrategyCondition: Sickle Cell AnemiaInterventions: Drug: Rapid optimized analgesic strategy; Drug: current analgesic strategy Sponsor: Assistance Publique - Hôpitaux de Paris Completed Thu, 02 Apr 2009 12:00:00 EDT Multimodal Analgesia in Cardiac Surgery (Pilot Study)Condition: Heart DiseasesInterventions: Drug: Lidocaine; Drug: Unrestricted Fentanyl; Drug: Ketamine; Drug: Precedex; Drug: Duramorph Sponsor: Virginia Commonwealth University Terminated Tue, 12 Apr 2016 12:00:00 EDT Patient-controlled Sedation With Propofol Versus Combined Sedation During BronchoscopyCondition: Sedation, BronchoscopyInterventions: Drug: Midazolam; Drug: Propofol-Lipuro; Drug: morphine-scopolamine; Drug: Glycopyrrolate Sponsor: Lena Nilsson Completed Wed, 29 Nov 2017 12:00:00 EST Lumbar Erector Spinae Plane Block for Back SurgeryConditions: Pain, Postoperative; Anaesthesia; Surgery; Nerve Block; Anesthesia, Local; Back Pain; Spinal FusionInterventions: Procedure: Erector spinae plane block; Drug: Levobupivacaine 0,25%; Procedure: spine fusion; Drug: NaCL 0,9%; Drug: Sufentanil; Drug: propofol; Drug: Rocuronium Bromide; Drug: sevoflurane; Drug: paracetamol; Drug: Ketorolac; Drug: morphine pca; Drug: Dexamethasone; Drug: Morphine Sponsor: Dr M. B. Breebaart Recruiting Thu, 31 Jan 2019 12:00:00 EST Effects of Anesthetic Technique on Immune and Inflammatory Systems Following Radical ProstatectomyCondition: Prostate CancerInterventions: Drug: Patient controlled analgesia (PCA); Drug: Thoracic Epidural Analgesia (TEA) Sponsor: Örebro University, Sweden Completed Tue, 07 Jun 2011 12:00:00 EDT Multisystemic Therapy-Emerging Adults TrialCondition: Antisocial BehaviorInterventions: Behavioral: Multisystemic Therapy for Emerging Adults; Behavioral: Enhanced Treatment as Usual Sponsors: University of Massachusetts, Worcester; National Institute of Mental Health (NIMH); Oregon Social Learning Center; Connecticut Department of Children and Families; North American Family Institute; Court Support Services Division; Youth Villages Active, not recruiting Tue, 04 Oct 2016 12:00:00 EDT An Extension of the TG1101-RMS201 TrialCondition: Relapsing Remitting Multiple SclerosisIntervention: Biological: Ublituximab Sponsor: TG Therapeutics, Inc. Active, not recruiting Thu, 21 Dec 2017 12:00:00 EST
Morphine Consumption in Joint Replacement Patients, With or Without Gabapentin TreatmentConditions: Post Operative Pain; Total Knee ReplacementInterventions: Drug: Gabapentin; Drug: Placebo Sponsors: McMaster University; Hamilton Health Sciences Corporation Completed Wed, 02 Mar 2011 12:00:00 EST A Clinical Study of SHR8554 Injection for the Treatment of Pain After Orthopedic SurgeryCondition: PainInterventions: Drug: SHR8554; Drug: Saline Solution; Drug: Morphine Sponsor: Jiangsu HengRui Medicine Co., Ltd. Recruiting Fri, 12 Mar 2021 12:00:00 EST A Clinical Study of SHR8554 Injection for the Treatment of Pain After Abdominal Surgery.Condition: PainInterventions: Drug: SHR8554 Injection; Drug: Placebo; Drug: Morphine Sponsor: Jiangsu HengRui Medicine Co., Ltd. Enrolling by invitation Tue, 23 Feb 2021 12:00:00 EST Study of Evobrutinib in Participants With RMSCondition: Relapsing-remitting Multiple SclerosisInterventions: Drug: Evobrutinib; Drug: Avonex®; Drug: Avonex® matched Placebo; Drug: Evobrutinib matched Placebo Sponsors: EMD Serono Research & Development Institute, Inc.; Merck KGaA, Darmstadt, Germany Terminated Thu, 25 Jul 2019 12:00:00 EDT Using Mobile Technology to Enhance Multisystemic Therapy (MST) OutcomesCondition: Child Behavior DisordersIntervention: Device: VillageWhere App Sponsors: Evidence-Based Practice Institute, Seattle, WA; National Institute of Mental Health (NIMH); Medical University of South Carolina Completed Fri, 19 Dec 2014 12:00:00 EST Connecting Women to Care: Home-based Psychotherapy for Women With MST Living in Rural AreasCondition: PTSDInterventions: Behavioral: STAIR; Behavioral: PCT Sponsors: VA Office of Research and Development; San Diego Veterans Healthcare System Recruiting Mon, 12 Feb 2018 12:00:00 EST Magnesium Associated With Morphine for Cancer Pain ReliefCondition: Cancer-related Problem/ConditionIntervention: Drug: Magnesiun Sponsor: Federal University of São Paulo Completed Wed, 29 Feb 2012 12:00:00 EST Effects of a Surgical Site Injection on Pain Scores and Narcotic Use After Orthopaedic Trauma SurgeryCondition: Pertrochanteric FractureInterventions: Drug: Marcaine, Duramorph , ketorolac; Drug: Bupivacaine (Marcaine); Drug: General Anesthetics Sponsor: NYU Langone Health Completed Wed, 03 Oct 2018 12:00:00 EDT Evaluation of Maxillary and Mandibulary Nerve Blocks on Morphine ConsumptionCondition: Dento Facial DysmorphismInterventions: Procedure: Maxillary and mandibular blocks; Procedure: General anesthesia Sponsor: Hospices Civils de Lyon Completed Tue, 03 Oct 2017 12:00:00 EDT The Effect of Intraoperative Dexmedetomidine on Postoperative Morphine Requirements After Breast Cancer SurgeryCondition: Morphine ConsumptionInterventions: Drug: Dexmedetomidine; Drug: placebo Sponsor: National Taiwan University Hospital Not yet recruiting Wed, 01 Jul 2020 12:00:00 EDT
FaR-RMS: An Overarching Study for Children and Adults With Frontline and Relapsed RhabdoMyoSarcomaCondition: RhabdomyosarcomaInterventions: Drug: Irinotecan; Drug: Actinomycin D; Drug: Doxorubicin; Drug: Ifosfamide; Drug: Vincristine; Drug: Vinorelbine; Drug: Cyclophosphamide; Drug: Temozolomide; Radiation: radiotherapy Sponsor: University of Birmingham Recruiting Thu, 12 Nov 2020 12:00:00 EST Dexmedetomidine as Adjuvant for FNB in TKAConditions: Nerve Block; DexmedetomidineInterventions: Drug: Dexmedetomidine; Procedure: ultrasound-guided femoral nerve block; Device: intravenous patient-controlled analgesia pump with morphine; Procedure: Continuous femoral nerve block Sponsor: First Affiliated Hospital, Sun Yat-Sen University Completed Wed, 05 Sep 2018 12:00:00 EDT Effect of Gabapentin on Postoperative Morphine Consumption After Sleeve GastrectomyCondition: Postoperative ComplicationsInterventions: Drug: Gabapentin; Drug: Placebo Oral Capsule Sponsor: King Saud University Completed Wed, 18 Jan 2017 12:00:00 EST Assessing a Clinically-meaningful Opioid Withdrawal PhenotypeConditions: Opioid Withdrawal; Opioid Use Disorder; Opioid CravingInterventions: Drug: Morphine; Drug: Naloxone + lofexidine pretreatment; Drug: Naloxone + placebo pretreatment; Drug: Lofexidine Sponsors: Johns Hopkins University; National Institute on Drug Abuse (NIDA) Not yet recruiting Tue, 31 Aug 2021 12:00:00 EDT Postoperative Pain and Morphine Consumption After Mastectomy - LyricaCondition: Post-operative PainIntervention: Drug: lyrica Sponsors: University of Texas Southwestern Medical Center; Pfizer Completed Tue, 12 Jul 2011 12:00:00 EDT Preoperative Methadone Single Dose Reduces Postoperative Morphine Consumption.Condition: Pain, PostoperativeIntervention: Drug: Methadone Sponsor: Kantonsspital Baden Completed Fri, 18 May 2018 12:00:00 EDT Interest of the Nefopam and PCA Morphine Combination for Postoperative Analgesia in Patients Undergoing Colon SurgeryConditions: Colonic Neoplasms; Diverticulosis, ColonicInterventions: Drug: Nefopam; Other: saline solution Sponsor: Centre Hospitalier Universitaire de Nīmes Completed Wed, 08 Aug 2018 12:00:00 EDT Anti Emetic Efficacy of Combination of Ramosetron and Premixture of Naloxone With Patient-controlled AnalgesiaCondition: Postoperative Nausea and VomitingInterventions: Drug: Ramosetron; Drug: Naloxone; Drug: saline; Drug: Morphine Sponsor: Kyungpook National University Hospital Completed Tue, 14 Apr 2015 12:00:00 EDT A Study of Suboptimally Controlled Participants Previously Taking Injectable DMDs for RMS (CLICK-MS)Condition: Multiple SclerosisIntervention: Drug: Cladribine Tablets Sponsors: EMD Serono Research & Development Institute, Inc.; Merck KGaA, Darmstadt, Germany Recruiting Wed, 01 May 2019 12:00:00 EDT Morphine COnsumption in Joint Replacement Patients, With and Without GaBapentin Treatment, a RandomIzed ControlLEd StudyConditions: Postoperative Pain; Total Hip ReplacementInterventions: Drug: Gabapentin; Other: Placebo Sponsor: Hamilton Health Sciences Corporation Completed Tue, 28 Apr 2009 12:00:00 EDT
Multimodal Analgesic Using Morphine and COX-2 With or Without Dexmedetomidine for Colorectal SurgeryCondition: Pain, PostoperativeInterventions: Drug: Dexmedetomidine; Drug: Normal Saline Sponsor: The University of Hong Kong Completed Fri, 13 May 2011 12:00:00 EDT A Study of Suboptimally Controlled Participants Previously Taking Oral or Infusion DMDs for RMS (MASTER-2)Condition: Multiple SclerosisIntervention: Drug: Cladribine Tablets Sponsors: EMD Serono Research & Development Institute, Inc.; Merck KGaA, Darmstadt, Germany Recruiting Wed, 01 May 2019 12:00:00 EDT Impact of a Strategy Combining Morphine Savings and Anesthesia Technique on the Quality of Post-operative RehabilitationCondition: Cesarean Section ComplicationsIntervention: Sponsor: Centre Hospitalier Régional Metz-Thionville Recruiting Thu, 07 May 2020 12:00:00 EDT Evaluation of the Analgesia Nociception Index and Videopupillometry to Predict a Child's Post-tonsillectomy Morphine PrescriptionCondition: Pain, PostoperativeIntervention: Other: Nerve stimulation of the ulnar nerve Sponsor: University Hospital, Limoges Completed Tue, 09 Oct 2018 12:00:00 EDT Ketamine Combination With Spinal Morphine for Post Thoracic Surgery Pain : A Randomized Control StudyConditions: Pain; Postoperative PeriodInterventions: Other: NSS; Drug: Ketamine Sponsor: Mahidol University Completed Wed, 07 Oct 2015 12:00:00 EDT Photobiomodulation Therapy in Exercise Capacity Assessed by 6MST in Patients With COPDCondition: Chronic Obstructive Pulmonary Disease (COPDIntervention: Device: Photobiomodulation Therapy (PBMT) Sponsor: University of Nove de Julho Completed Tue, 21 Aug 2018 12:00:00 EDT SWC on aEEG in Post-surgical Neonates on Morphine and MidazolamConditions: Neurology; Newborn; Analgesia; Sedation; SurgeryIntervention: Sponsor: Royal Children's Hospital Completed Thu, 30 Sep 2010 12:00:00 EDT Effect of Intraoperative IV Ketamine on Postoperative Morphine Consumption During Intestinal SurgeryCondition: Postoperative AnalgesiaInterventions: Drug: Ketamine Hydrochloride; Drug: Normal saline Sponsor: Assiut University Unknown status Fri, 17 Nov 2017 12:00:00 EST Relation of Obesity With Frequency of Meals (MST 0557)Conditions: Obesity; Insulin Resistance; Fatty LiverInterventions: Other: high frequency of meals; Other: twice a day meals Sponsors: Rockefeller University; Cornell University Completed Thu, 29 Sep 2005 12:00:00 EDT Low-level Laser Acupuncture Reduces Postoperative Pain and Morphine-related Side Effects in Patients With Total Knee Arthroplasty:Condition: Low-level Laser Acupuncture in Patients With Total Knee ArthroplastyInterventions: Device: low-level laser; Device: Sham laser Sponsor: Taipei Veterans General Hospital, Taiwan Completed Mon, 24 Jun 2019 12:00:00 EDT
Vancomycin Associated Red Man Syndrome (RMS)Condition: Red Man SyndromeIntervention: Sponsors: Children's Mercy Hospital Kansas City; Katherine Berry Richardson Foundation Completed Fri, 16 Jan 2009 12:00:00 EST The Standard Concentration of Morphine as a Positive Control for Intradermal Skin TestCondition: Intradermal TestIntervention: Sponsor: Chulalongkorn University Completed Mon, 02 Mar 2009 12:00:00 EST Adductor Canal Block With Continuous Infusion Versus Intermittent Boluses and Morphine ConsumptionCondition: Postoperative PainIntervention: Drug: ropivacaine 0.2% Sponsors: Pia Jaeger; University of California, San Diego; Bispebjerg Hospital; Smiths Medical, ASD, Inc. Completed Thu, 03 Sep 2015 12:00:00 EDT Celecoxib for Reducing Morphine Requirement After Thyroid Surgery: A Randomized Controlled TrialConditions: Postoperative Pain; Thyroidectomy; Cyclooxygenase 2 InhibitorsIntervention: Drug: celecoxib Sponsor: Mahidol University Completed Fri, 24 Aug 2007 12:00:00 EDT Evaluation of the Relationship Between ABCG2 Mutation and Teriflunomide Exposure and Safety in Chinese RMS Patients Treated With Teriflunomide 14 mg Once Daily for 24 WeeksCondition: Multiple SclerosisIntervention: Drug: TERIFLUNOMIDE Sponsor: Sanofi Completed Mon, 01 Jun 2020 12:00:00 EDT Methylnaltrexone as a Method to Improve Ticagrelor Uptake in Morphine Treated STEMI PatientsConditions: STEMI; Morphine; Ticagrelor; MethylnaltrexoneInterventions: Drug: Methylnaltrexone bromide (Relistor®).; Drug: Sodium Chloride 9mg/mL Sponsor: Karolinska University Hospital Completed Mon, 24 Oct 2016 12:00:00 EDT Programmed Intermittent Bolus Versus Continuous Infusion for Epidural Analgesia in Abdominal SurgeryConditions: Analgesia, Epidural; Pain, PostoperativeInterventions: Device: Programmed intermittent epidural bolus (PIEB) of bupicavaine; Device: Continuous epidural infusion (CEI) of bupivacaine; Device: Continuous epidural infusion (CEI) of morphine Sponsor: CHU de Quebec-Universite Laval Completed Wed, 05 Feb 2020 12:00:00 EST Efficacy and Safety of Q8003 in the Management of Post-bunionectomy PainCondition: Postoperative PainInterventions: Drug: Q8003 (morphine sulfate and oxycodone hydrochloride); Drug: Placebo Sponsor: QRxPharma Inc. Completed Mon, 19 Nov 2007 12:00:00 EST SMART Design to Compare Antipsychotic Treatments in Treatment-Resistant SchizophreniaCondition: Treatment-resistant SchizophreniaInterventions: Drug: Clozapine; Device: MECT; Device: DBS Sponsor: Shanghai Mental Health Center Not yet recruiting Thu, 27 Aug 2020 12:00:00 EDT The Efficacy of Adductor-Canal-Blockade on Pain and Morphine Consumption After Total Knee ArthroplastyConditions: Postoperative Pain; Knee ArthroplastyInterventions: Procedure: Adductor-Canal-Blockade with Ropivacaine; Procedure: Adductor-Canal-blockade with saline Sponsor: Rigshospitalet, Denmark Completed Fri, 17 Dec 2010 12:00:00 EST
Use of Virtual Reality to Reduce Morphine Consumption in Adolescents Undergoing Scoliosis SurgeryCondition: ScoliosisInterventions: Device: Virtual Reality (VR) technique; Drug: Analgesic protocol Sponsor: University Hospital, Toulouse Not yet recruiting Wed, 19 May 2021 12:00:00 EDT An Open-label Study Evaluating Ofatumumab Treatment Effectiveness and PROs in Subjects With RMS Transitioning From Dimethyl Fumarate or Fingolimod to OfatumumabCondition: Relapsing Multiple SclerosisIntervention: Biological: Ofatumumab Sponsor: Novartis Pharmaceuticals Recruiting Mon, 20 Apr 2020 12:00:00 EDT Intraarticular Analgesia After Total Hip Arthroplasty, a Randomised StudyCondition: Arthroplasty, Replacement, HipInterventions: Drug: Epidural Ropivacaine, morphine; Drug: Ropivacaine, Ketorolac and Adrenaline Sponsor: University of Aarhus Completed Thu, 09 Feb 2006 12:00:00 EST The Efficacy of Adductor-Canal-Blockade on Pain and Morphine Consumption After Revision Knee ArthroplastyConditions: Postoperative Pain; Knee ArthroplastyInterventions: Procedure: Adductor-Canal-Blockade with Ropivacaine; Procedure: Adductor-Canal-blockade with saline Sponsor: Rigshospitalet, Denmark Completed Tue, 31 Aug 2010 12:00:00 EDT Comparison of Different Methods of Pain Control After Cesarean Section for Patients on Buprenorphine or MethadoneCondition: Caesarean DeliveryInterventions: Drug: TAP Block; Drug: Ropivacaine; Drug: Acetaminophen; Drug: Morphine Sponsors: Dartmouth-Hitchcock Medical Center; Massachusetts General Hospital; Brigham and Women's Hospital Withdrawn Wed, 19 Mar 2014 12:00:00 EDT Continuous Wound Catheter Analgesia Associated With Intravenous Morphine PCA After ThoracotomyConditions: Pain; ThoracotomyInterventions: Drug: ropivacaine 0.75% - device : wound catheter Silver™ 19 cm and Easypump™ 400 mL (BBraun); Drug: Placebo; Drug: ropivacaine 0.2% - device : wound catheter Silver™ 19 cm and Easypump™ 400 mL (BBraun) Sponsor: University Hospital, Strasbourg, France Completed Tue, 02 Oct 2012 12:00:00 EDT A 12 Week Randomized Open Label Parallel Group Multicenter Study to Evaluate Bioequivalence of 20 mg Subcutaneous Ofatumumab Injected by Pre-filled Syringe or Autoinjector in Adult RMS PatientsCondition: Multiple SclerosisInterventions: Combination Product: ofatumumab with PRF; Combination Product: ofatumumab with AI Sponsor: Novartis Pharmaceuticals Completed Mon, 18 Jun 2018 12:00:00 EDT The Effect of Intraoperative Nefopam, Ketoprofen and Paracetamol Combination vs Ketoprofen and Paracetamol Combination on Postoperative Morphine Requirements After Laparoscopic Cholecystectomy: A Randomized, Controlled TrialConditions: Cholecystectomy; Pain, Postoperative; Opioid UseInterventions: Drug: nefopam, ketoprofen, paracetamol; Drug: saline infusion, ketoprofen, paracetamol Sponsor: American University of Beirut Medical Center Recruiting Tue, 10 Nov 2020 12:00:00 EST The Efficacy of Adductor-Canal-Blockade on Morphine Consumption, Pain and Mobilisation After Total Knee ArthroplastyCondition: Total Knee ArthroplastyInterventions: Procedure: Adductor-Canal-Blockade; Procedure: Adductor-Canal-blockade with saline Sponsor: Rigshospitalet, Denmark Completed Fri, 16 Apr 2010 12:00:00 EDT Using Patient Reported Outcomes (PROs) to Evaluate Teriflunomide Treatment in Relapsing Multiple Sclerosis (RMS) PatientsCondition: Multiple SclerosisIntervention: Drug: Teriflunomide Sponsor: Sanofi Completed Wed, 10 Jul 2013 12:00:00 EDT
Morphine-Sparing Effect And Safety Of Parecoxib Administered Intravenously For The Treatment Of Postoperative PainCondition: Pain, PostoperativeIntervention: Drug: Parecoxib and placebo Sponsor: Pfizer Completed Fri, 02 Sep 2005 12:00:00 EDT Impact of Disease Modifying Therapies (DMTs) and Associated Support Services in Relapsing Multiple Sclerosis (RMS) PatientsCondition: Relapsing Multiple SclerosisInterventions: Drug: Rebif; Other: Other: Disease modifying therapies (DMT) Sponsors: Merck KGaA, Darmstadt, Germany; Merck Serono Limited, UK Completed Thu, 17 May 2012 12:00:00 EDT Etoricoxib With Flavoxate for Reducing Morphine Requirement After Transurethral Prostatectomy (TURP)Condition: PainInterventions: Drug: etoricoxib; Drug: flavoxate; Drug: etoricoxib, flavoxate; Drug: placebo Sponsor: Mahidol University Completed Tue, 27 Feb 2007 12:00:00 EST Hydroxyzine for the Prevention of Pruritus From Spinal Morphine in Transabdominal Hysterectomy PatientsConditions: Pruritus; Nausea; VomitingIntervention: Drug: hydroxyzine Sponsor: Mahidol University Completed Mon, 25 Jan 2010 12:00:00 EST Influence of Intraoperative Analgesia on the Postoperative Morphine ConsumptionCondition: AnesthesiaInterventions: Drug: Remifentanil; Drug: Sufentanil Sponsor: Hopital Foch Completed Wed, 15 Oct 2008 12:00:00 EDT Effects of Perioperative B&O Suppositories on Post-op Pain and Morphine Use After Laparoscopic ProstatectomyCondition: PainIntervention: Drug: belladonna 16.2 mg and opium 60 mg suppository Sponsors: Benaroya Research Institute; Virginia Mason Hospital/Medical Center Completed Wed, 18 Mar 2009 12:00:00 EDT Effect of Combinations of Paracetamol, Ibuprofen, and Dexamethasone on Patient-Controlled Morphine Consumption in the First 24 Hours After Total Hip ArthroplastyConditions: Pain, Acute; Hip Arthropathy; Analgesia; Postoperative PainInterventions: Drug: Paracetamol; Drug: Ibuprofen (400 mg x 4); Drug: Dexamethasone; Drug: Placebo oral tablet (x 4); Drug: Placebo IV (x 1) Sponsor: Naestved Hospital Recruiting Fri, 11 Oct 2019 12:00:00 EDT The Use of Low Dose Prophylactic Naloxone Infusion to Prevent Respiratory Depression With Intrathecal Morphine.Condition: Respiratory DepressionInterventions: Drug: Naloxone; Drug: Placebo Sponsor: University College Dublin Completed Thu, 01 Sep 2016 12:00:00 EDT Study to Explore Effectiveness of Sublingual Fentanyl Spray in Emergency Department Patients With Acute PainCondition: Acute PainInterventions: Drug: Morphine 6 mg; Drug: Fentanyl 100 µg; Drug: Fentanyl 200 µg; Drug: Fentanyl 400 µg; Drug: Placebo Sublingual Spray; Drug: Intravenous Placebo Sponsor: INSYS Therapeutics Inc Withdrawn Wed, 14 May 2014 12:00:00 EDT Optimizing Outpatient Anesthesia (OSPREy-Outpatient Surgery Pain Relief Enhancement)Conditions: Opioid Use; Pain, PostoperativeInterventions: Drug: Methadone; Drug: Fentanyl; Drug: Hydromorphone; Drug: Morphine; Drug: Sufentanil Sponsors: Duke University; National Institute on Drug Abuse (NIDA) Recruiting Wed, 31 Oct 2018 12:00:00 EDT
Nefopam and Morphine Consumption in the Treatment of Ureteral CalculiCondition: Ureteral Calculi, Hyperalgic, Not ComplicatedIntervention: Drug: Néfopam Sponsor: University Hospital, Clermont-Ferrand Completed Thu, 20 Mar 2008 12:00:00 EDT Reduction of Bladder Injection Pain With Belladonna Opiate SuppositoryConditions: Overactive Bladder; Urinary Urge Incontinence; Urinary Bladder, Neurogenic; Painful Bladder SyndromeInterventions: Drug: Onabotulinumtoxin A (BoNT); Drug: belladonna; Drug: Morphine; Drug: Placebo; Drug: Active B&O suppository of belladonna Sponsor: Edgar LeClaire, MD Completed Mon, 09 Nov 2015 12:00:00 EST Adductor Canal Nerve Block Following Total Knee ArthroplastyCondition: Post-op PainInterventions: Drug: Morphine PCA started at the end of surgery, 1 Percocet 1/325mg every 4 hours; may receive a second Percocet if needed.; Drug: For the 30ml ropivacaine the intervention would be the subject can request extra pain medication which would be Percocet and/or morphine PCA. Sponsor: Loma Linda University Withdrawn Wed, 11 Sep 2013 12:00:00 EDT 5HT3 Antagonists to Treat Opioid Withdrawal and to Prevent the Progression of Physical DependenceConditions: Opioid Withdrawal; Physical DependenceInterventions: Drug: Ondansetron; Drug: Placebo; Drug: Morphine; Drug: Naloxone 0.4 mg/70 kg; Drug: Naloxone 0.8 mg/70 kg Sponsors: Stanford University; National Institute on Drug Abuse (NIDA) Completed Fri, 09 Mar 2012 12:00:00 EST Recommendations of Enhanced Recovery Interventions for Patient's Clinical Team and Collection of Associated DataCondition: Perioperative OptimizationInterventions: Dietary Supplement: Gatorade ®; Dietary Supplement: Clearfast ®; Drug: Preoperative Gabapentin; Drug: Neuraxial Morphine Injection; Drug: Regional Technique Analgesia; Drug: Perphenazine; Drug: Aprepitant; Drug: Totally intravenous Anesthesia (TIVA); Other: Stroke volume comparator; Other: Fluid Therapy; Drug: Ketamine; Drug: Lidocaine; Drug: Intraoperative opioids; Drug: Primary Anesthetic Spinal; Drug: Primary Anesthetic Volatile Agent; Drug: Postoperative Gabapentin Sponsors: Jennifer Holder-Murray; Berry Consultants Not yet recruiting Wed, 28 Oct 2020 12:00:00 EDT Comparison of the Efficacy of Ketamine in Pediatric Patients With Idiopathic Scoliosis After SurgeryCondition: Progressive Infantile Idiopathic ScoliosisInterventions: Drug: Ketamine Hydrochloride; Other: Placebo; Drug: Remifentanil; Drug: Morphine hydrochloride Sponsors: Fundació Sant Joan de Déu; Instituto de Salud Carlos III Completed Thu, 08 Oct 2015 12:00:00 EDT Study to Explore the Mechanism of Action of Ocrelizumab and B-Cell Biology in Participants With Relapsing Multiple Sclerosis (RMS) or Primary Progressive Multiple Sclerosis (PPMS)Conditions: Relapsing Multiple Sclerorsis; Multiple Sclerosis, Primary ProgressiveInterventions: Drug: Ocrelizumab; Procedure: Lumbar Puncture; Drug: Methyloprednisolone; Drug: Antihistamine Sponsor: Genentech, Inc. Active, not recruiting Tue, 23 Feb 2016 12:00:00 EST Different Approaches to Maternal Hypotension During Cesarean SectionConditions: Pregnancy; Cesarean Section; Anesthesia,Spinal; HypotensionInterventions: Drug: Bupivacaine; Drug: Morphine; Drug: Lactated Ringer's solution; Drug: Ephedrine, continuous infusion; Drug: Ephedrine, bolus; Drug: Atropine Sponsors: University of Parma; Azienda Ospedaliero-Universitaria di Parma Completed Thu, 08 Oct 2009 12:00:00 EDT An Observational Study Comparing Multiple Sclerosis International Quality of Life Questionnaire (MusiQoL) and Multiple Sclerosis Quality of Life-54 Instrument (MSQOL-54) in Relapsing Multiple Sclerosis (RMS) Patients on Long-term Rebif® TherapyCondition: Multiple Sclerosis, Relapsing-RemittingIntervention: Sponsor: Merck KGaA, Darmstadt, Germany Completed Thu, 10 Jun 2010 12:00:00 EDT Prospective Study About Clinical and Pharmacogenetic Safety of Opioid Use for Chronic PainCondition: Chronic PainInterventions: Drug: Morphine; Drug: Oxycodone; Drug: Fentanyl; Drug: Buprenorphine Sponsors: IRCCS Policlinico S. Matteo; University of Pavia Suspended Wed, 10 Jun 2009 12:00:00 EDT
Liposomal Bupivacaine in Implant Based Breast ReconstructionConditions: Breast Cancer; Postoperative PainInterventions: Drug: Liposomal bupivacaine; Drug: Bupivacaine with epinephrine; Drug: Morphine sulfate; Drug: Hydrocodone/acetaminophen; Drug: Diazepam Sponsor: Loma Linda University Terminated Wed, 20 Jan 2016 12:00:00 EST Pain Relief for Ventilated Patients With Multiple Rib Fractures Using the ON-Q Pain Relief SystemCondition: Rib FracturesInterventions: Device: ON-Q bupivicaine administration; Drug: IV opioid administration Sponsor: The Cooper Health System Terminated Mon, 13 Apr 2009 12:00:00 EDT Comparison of Treatment by IM Ketamine to IV Ketamine in Patients With Renal ColicConditions: Acute Pain; Renal ColicInterventions: Drug: IV Ketamine; Drug: IM Ketamine Sponsor: Tel-Aviv Sourasky Medical Center Unknown status Wed, 10 Jul 2019 12:00:00 EDT is There an Alternative to Ultrasound Guided Interscalene Block?Conditions: Regional Anesthesia; Interscalene Block; Shoulder SurgeryInterventions: Drug: bupivacaine; Device: ultrasound; Drug: morphine Sponsor: Tunisian Military Hospital Unknown status Tue, 24 Mar 2015 12:00:00 EDT Hypothermia's Impact on PharmacologyConditions: Cardiac Arrest; HypothermiaIntervention: Sponsor: Children's Hospital of Philadelphia Completed Thu, 22 Mar 2012 12:00:00 EDT HLA-mismatched MST vs HLA-matched NST for AML in Intermediate-riskCondition: Acute Myeloid LeukemiaInterventions: Genetic: HLA mismatched stem cell; Genetic: HLA matched stem cell; Drug: cyclosporine A; Drug: Mycophenolate mofetil; Drug: Ara-C; Drug: fludarabine; Drug: anti-lymphocyte globulin; Drug: cyclophosphamide Sponsor: The Affiliated Hospital of the Chinese Academy of Military Medical Sciences Completed Wed, 03 Jun 2015 12:00:00 EDT Study of Buprenorphine Sublingual Spray Versus Standard of Care Narcotic Therapy for the Treatment of Post-Operative PainCondition: Pain, PostoperativeInterventions: Drug: Buprenorphine Sublingual Spray; Drug: Morphine; Drug: Oxycodone Hydrochloride; Drug: Zofran Sponsor: INSYS Therapeutics Inc Completed Fri, 18 Aug 2017 12:00:00 EDT Perioperative Use of Gabapentin To Decrease Narcotic Requirements in Spinal FusionCondition: Postoperative PainInterventions: Drug: Gabapentin; Drug: Placebo; Drug: Morphine Sponsors: Medical College of Wisconsin; Children's Hospital and Health System Foundation, Wisconsin Completed Fri, 01 Aug 2008 12:00:00 EDT Evaluation of the Roll of IV Fluids in the Treatment of Renal ColicCondition: Renal ColicInterventions: Drug: 0.9% Sodium-chloride; Drug: Placebos; Drug: Optalgin, Voltaren, Morphine Sponsor: Sheba Medical Center Withdrawn Fri, 18 May 2018 12:00:00 EDT Effect of Midazolam on Inflammatory Response and Organ Function in Mechanically Ventilated Sepsis Patients With Different Immune StatusConditions: Inflammatory Disorder of Immune System; SepsisInterventions: Other: blood sample collection; Drug: Midazolam; Drug: Morphine; Procedure: Sedation interruption Sponsor: Xiangya Hospital of Central South University Unknown status Fri, 09 May 2014 12:00:00 EDT
Patient Controlled Intrathecal Analgesia With Bupivacaine for Chronic Low Back PainConditions: Pain, Intractable; Breakthrough Pain; Chronic PainInterventions: Drug: Bupivacaine; Drug: Opioid Sponsor: University Hospitals Cleveland Medical Center Completed Thu, 01 Sep 2016 12:00:00 EDT Intravenous Paracetamol for Postoperative PainConditions: Pain, Postoperative; Recovery of Function; ChildInterventions: Drug: Paracetamol; Drug: Placebo (for paracetamol); Drug: Ketoprofen; Drug: Tramadol; Drug: Morphine Sponsor: Lithuanian University of Health Sciences Completed Thu, 25 Sep 2014 12:00:00 EDT Efficacy of Intramuscular Naloxone 0.4mg. in Prophylaxis of Intrathecal Morphine Induced Pruritus After Cesarean SectionCondition: Morphine Adverse ReactionInterventions: Drug: naloxone; Drug: normal saline Sponsor: Mahidol University Completed Thu, 30 Apr 2009 12:00:00 EDT Role of Multimodal Analgesia in Decreasing Perioperative Pain in Tibial Plateau FracturesCondition: Tibial Plateau FracturesInterventions: Drug: Injection; Drug: Injections Sponsor: University of Utah Enrolling by invitation Wed, 08 Sep 2021 12:00:00 EDT Effectiveness of Rebif® in Clinically Isolated Syndrome and Relapsing Multiple Sclerosis Using RebiSmart™Conditions: Relapsing Multiple Sclerosis; Clinically Isolated SyndromeIntervention: Drug: Rebif Sponsors: Merck KGaA, Darmstadt, Germany; Merck Romania SRL, an affiliate of Merck KGaA, Darmstadt, Germany Completed Wed, 01 Oct 2014 12:00:00 EDT Perineural Low-dose Dexamethasone Added to Infraclavicular Block AnesthesiaCondition: Postoperative PainInterventions: Drug: Dexamethasone; Drug: Ropivacaine; Drug: Paracetamol; Drug: Morphine; Drug: Lidocaine Sponsor: Foisor Orthopedics Clinical Hospital Completed Fri, 04 Mar 2016 12:00:00 EST NALDEBAIN for Postoperative Pain Management in Take Down of AnastomosisCondition: Postoperative PainInterventions: Drug: Naldebain; Drug: Morpine Sponsor: China Medical University Hospital Unknown status Tue, 26 Feb 2019 12:00:00 EST A Study to Evaluate the Efficacy and Safety of Tapentadol (CG5503) in the Treatment of Acute Pain After Abdominal HysterectomyConditions: Hysterectomy; PostoperativeInterventions: Drug: Morphine; Drug: CG5503 IR; Drug: Placebo Sponsors: Grünenthal GmbH; Johnson & Johnson Pharmaceutical Research & Development, L.L.C. Completed Thu, 24 May 2007 12:00:00 EDT Neurostimulation for the Treatment of Post-Operative IleusCondition: IleusIntervention: Device: ElectroCore RMS-1100 Resolution Motility System™ Sponsor: ElectroCore INC Withdrawn Mon, 02 Mar 2009 12:00:00 EST BIOSOLVE-IV Magmaris Swiss Satellite RegistryCondition: Coronary Artery DiseaseIntervention: Device: Magmaris Resorbable Magnesium Scaffold (RMS) Sponsor: University Hospital, Geneva Recruiting Fri, 19 Jul 2019 12:00:00 EDT
Treatment Adherence When Using RebiSmart™ in Relapsing Multiple Sclerosis SubjectsConditions: Multiple Sclerosis; MSIntervention: Device: RebiSmart™ Sponsors: Merck KGaA, Darmstadt, Germany; EMD Inc., Canada Completed Fri, 21 May 2010 12:00:00 EDT OSA Screen Negative With Spinal DuramorphCondition: Respiratory DepressionIntervention: Device: Capnography monitoring Sponsor: Wake Forest University Health Sciences Terminated Fri, 12 May 2017 12:00:00 EDT Perineural Dexamethasone in Femural Nerve Block After Ligament ReconstructionCondition: Postoperative PainInterventions: Drug: Dexamethasone phosphate; Drug: Paracetamol; Drug: Morphine; Drug: Lidocaine; Drug: Ropivacaine Sponsor: Foisor Orthopedics Clinical Hospital Completed Fri, 22 Apr 2016 12:00:00 EDT Estimation of the ED95 of Intrathecal Hyperbaric Prilocaine 2% With Sufentanyl for Scheduled Cesarean DeliveryCondition: Pregnant WomenInterventions: Drug: HB Prilocaine 2% (varying dose); Drug: HB Prilocaine 2%; Drug: Sufentanil; Drug: Morphine Sponsor: Centre Hospitalier Universitaire Saint Pierre Completed Mon, 30 Jan 2017 12:00:00 EST Low Dose Ketamine Infusion for Postoperative Analgesia After Total Knee ArthroplastyCondition: Postoperative PainIntervention: Sponsor: Mustafa Kemal University Completed Wed, 11 Sep 2019 12:00:00 EDT Safety and Efficacy of Cocktail Periarticular Injection in Simultaneous Total Knee ArthroplastyCondition: Pain, PostoperativeIntervention: Drug: ropivacaine, fentanyl, adrenaline Sponsor: Peking Union Medical College Hospital Completed Tue, 21 Oct 2014 12:00:00 EDT Comparison of Butorphanol and Tramadol Associated Patient-Controlled Analgesia (PCA) After HysterectomyConditions: Postoperative Pain; HysterectomyInterventions: Drug: Saline; Drug: Butorphanol tartrate; Drug: Tramadol Hydrochloride Sponsors: Nanjing Medical University; HRSA/Maternal and Child Health Bureau Completed Thu, 02 Aug 2007 12:00:00 EDT Evaluation of Non-opioid Balanced General Anesthesia in Cardiac Surgery With Extracorporeal Circulation: a Randomized, Controlled, Multicenter Superiority TrialConditions: Opioid-free Anesthesia; Cardiac SurgeryInterventions: Drug: Balanced general anesthesia without morphine; Drug: Standard general anesthesia balanced with morphine; Other: Data collection; Other: Assessment of pain; Other: Recovery quality score Sponsor: Centre Hospitalier Universitaire Dijon Recruiting Fri, 14 May 2021 12:00:00 EDT Nerve Block Versus Non-targeted Local Anaesthesia in Breast SurgeryCondition: Pain, Post OperativeInterventions: Other: targeted chirocaine pec block; Other: standard chirocaine infiltration; Other: standard post-operative analgesia Sponsor: BMI Healthcare Unknown status Wed, 08 Apr 2015 12:00:00 EDT Pain in Patients With Dementia and Behavioural DisturbancesConditions: Dementia; Pain; AgitationInterventions: Drug: Paracetamol; Drug: Morphine; Drug: Buprenorphine plaster; Drug: Pregabalin Sponsors: University of Bergen; The Research Council of Norway Completed Mon, 30 Nov 2009 12:00:00 EST
Perioperative Analgesia for Knee Arthroplasty (PAKA)Condition: Knee ArthritisInterventions: Drug: Femoral Nerve Block; Drug: peri-articular infiltration Sponsor: University of Warwick Completed Thu, 22 Mar 2012 12:00:00 EDT Multistimulation Group Therapy for Alzheimer's DiseaseCondition: Alzheimer's DiseaseIntervention: Other: Multidimensional stimulation group therapy Sponsor: Fondazione Don Carlo Gnocchi Onlus Completed Tue, 09 Jul 2013 12:00:00 EDT Berlin Magnetic Seizure Therapy Depression Trial 01Conditions: Unipolar Depression; Bipolar DepressionIntervention: Procedure: magnetic seizure therapy Sponsor: Charite University, Berlin, Germany Completed Fri, 05 Jun 2009 12:00:00 EDT Opioid Receptors Influence Ischemia-Reperfusion InjuryCondition: Ischemia-Reperfusion InjuryInterventions: Drug: morphine; Drug: naloxone; Drug: Technetium-TC99m-labeled Annexin A5; Procedure: forearm ischemic exercise; Procedure: ten minute forearm ischemia Sponsor: Radboud University Suspended Fri, 16 Sep 2005 12:00:00 EDT Cognitive Function and Addiction Under Opioid TaperingConditions: Chronic Pain; Opioid UseInterventions: Drug: Opioids taper off; Drug: Opioid stable treatment Sponsors: Rigshospitalet, Denmark; The Ministry of Science, Technology and Innovation, Denmark; Hørslev-Fonden Completed Thu, 07 Dec 2017 12:00:00 EST Opioid-Free Anesthetic for TonsillectomyConditions: Anesthesia; Opioid Use; Tonsillitis; Sleep Disorder; SurgeryInterventions: Drug: Ketorolac; Drug: Dexmedetomidine; Drug: Morphine; Drug: Fentanyl Sponsors: Children's Hospital of Philadelphia; University of Pennsylvania; University of Tennessee Health Science Center Recruiting Thu, 27 Aug 2020 12:00:00 EDT The Effect of Dexamethasone in Combination With Paracetamol and Ibuprofen on Postoperative Pain After Spine SurgeryCondition: PainInterventions: Drug: Dexamethasone; Other: Placebo; Drug: Morphine; Drug: Zofran; Drug: Paracetamol; Drug: Ibuprofen Sponsors: Rigshospitalet, Denmark; Glostrup University Hospital, Copenhagen Completed Tue, 01 Oct 2013 12:00:00 EDT Tramadol to Reduce Opioid Withdrawal SymptomsCondition: Opioid-Related DisordersInterventions: Drug: Tramadol; Drug: Naloxone; Drug: Morphine Sponsor: National Institute on Drug Abuse (NIDA) Completed Fri, 02 Sep 2005 12:00:00 EDT Parent Nurse Controlled Analgesic in Pediatric Patients With Developmental DelayCondition: Post Operative PainInterventions: Other: Pain and standard side effect management for PNCA with basal method.; Other: Pain and standard side effect management with PNCA without basal; Other: Pain and standard side effect management with IV on an as needed basis method. Sponsors: Medical College of Wisconsin; Children's Hospital and Health System Foundation, Wisconsin Completed Fri, 29 Aug 2008 12:00:00 EDT Local Multimodal Injection Versus Regional Anesthesia in Controlling Pain for Treating Rotational Ankle FracturesCondition: Ankle FracturesInterventions: Drug: Regional anesthesia group; Drug: Local multimodal analgesia group Sponsor: University of Utah Enrolling by invitation Wed, 25 Aug 2021 12:00:00 EDT
Effectiveness of Analgesia in Total Knee ArthroplastyCondition: PainInterventions: Drug: several drugs: morphine chloride,ropivacaine,epinephrine,ketorolac; Drug: ropivacaine,morphine chloride,epinephrine,ketorolac; Drug: ropivacaine; Drug: morphine ,ketorolac Sponsor: Jose Antonio Bernia Gil Completed Fri, 25 Feb 2011 12:00:00 EST Granisetron vs Granisetron and Dexamethasone on the Reduction of Postoperative Nausea and VomitingCondition: PONVInterventions: Drug: Granisetron 1 Mg/mL Intravenous Solution And Dexamethasone 4mg; Drug: Granisetron 1 Mg/mL Intravenous Solution Sponsor: Universiti Sains Malaysia Recruiting Wed, 30 Sep 2020 12:00:00 EDT Study to Evaluate the Efficacy, Safety and Tolerability of N1539Condition: HysterectomyInterventions: Drug: N1539; Drug: placebo; Drug: Morphine Sponsor: Alkermes, Inc. Completed Wed, 10 Mar 2010 12:00:00 EST Collection of Blood Samples From Patients With Relapsing MS Who Developed ITP After Receiving LemtradaCondition: Multiple SclerosisIntervention: Other: Blood draw for future biomarker analysis Sponsor: Genzyme, a Sanofi Company Completed Mon, 24 Dec 2018 12:00:00 EST TQL-block for Laparoscopic HemicolectomyCondition: Postoperative PainInterventions: Drug: Ropivacaine; Drug: Acetaminophen; Device: Patient controlled analgesia; Drug: Morphine; Drug: Saline; Diagnostic Test: Blood samples; Behavioral: Quality of recovery-15 questionaire; Diagnostic Test: Orthostatic hypotension Sponsor: Zealand University Hospital Completed Wed, 27 Jun 2018 12:00:00 EDT Pharmacokinetics and Pharmacodynamics Study of RPC1063 in RMSCondition: Multiple SclerosisIntervention: Drug: RPC1063 Sponsor: Celgene Completed Mon, 13 Jun 2016 12:00:00 EDT S Ketamine Use in Total Abdominal HysterectomyCondition: Total Abdominal HysterectomyIntervention: Drug: S Ketamine Sponsor: KK Women's and Children's Hospital Withdrawn Mon, 07 Sep 2015 12:00:00 EDT Psoas Compartment Block Versus Periarticular Local Anesthetic for Total Hip ArthroplastyConditions: Osteoarthritis; ArthroplastyInterventions: Drug: Ropivacaine with NaCl; Drug: Epinephrine; Drug: Morphine; Drug: Ketorolac Tromethamine; Drug: Ropivacaine Sponsor: William Beaumont Hospitals Completed Mon, 18 Jan 2016 12:00:00 EST PVB vs PECS Block in Breast SurgeryCondition: Reconstruction Breast SurgeryInterventions: Procedure: Paravertebral Thoracic block; Procedure: Pectorals nerve block; Drug: Levobupivacaine 0.25%; Drug: Morphine Sponsor: Istituti Ospitalieri di Cremona Completed Tue, 09 Feb 2016 12:00:00 EST Analgesic Strategies in Newborns Receiving Prostaglandin TherapyCondition: PainInterventions: Drug: acetaminophen and nalbuphine; Drug: acetaminophen and morphine; Drug: acetaminophen and reduced dosage of prostaglandin Sponsor: Nantes University Hospital Terminated Tue, 20 Sep 2005 12:00:00 EDT
Regional vs General Anesthesia in Patients With Hip Fracture Under Treatment With ClopidogrelCondition: Hip FracturesInterventions: Drug: Fentanyl; Drug: Propofol; Drug: Rocuronium; Drug: Chirochaine; Drug: Morphine Sponsor: Larissa University Hospital Recruiting Mon, 23 Jul 2018 12:00:00 EDT Effects of Visceral Manipulation in Women With Urinary IncontinenceCondition: Urinary IncontinenceInterventions: Other: Pelvic Floor muscle training - PFMT; Other: Visceral Manual Therapy - VMT; Other: Manual Sham Therapy - MST Sponsor: University of the State of Santa Catarina Completed Fri, 10 May 2019 12:00:00 EDT Multimodal Analgesia in Shoulder ArthroplastyConditions: Shoulder Pain; Opioid UseInterventions: Drug: Acetaminophen; Drug: Celecoxib 200mg; Drug: Celecoxib 400 mg; Drug: Ropivacaine; Drug: Ketorolac; Drug: Acetaminophen Injectable Product; Drug: Oxycodone; Drug: Tramadol; Drug: Morphine Injectable Solution; Drug: hydrocodone bitartrate and acetaminophen; Drug: Morphine; Drug: Oxycodone Hydrochloride; Drug: Meloxicam Sponsor: Rush University Medical Center Withdrawn Mon, 16 Jul 2018 12:00:00 EDT Colloid Pre-Loading on D-Dimer During Cesarean Section Under Spinal AnesthesiaCondition: Coagulation Defect; BleedingInterventions: Drug: hydroxyethyl starch (6% 130/0.4); Drug: Hyperbaric bupivacaine; Drug: Morphine; Drug: Isotonic 0.9 sodium chloride (NaCl) solution; Drug: Ephedrine; Drug: Atropine Sponsor: Assiut University Completed Fri, 04 Dec 2015 12:00:00 EST US-guided SAPB for Rib Fractures in the EDConditions: Rib Fractures; Rib Fracture MultipleInterventions: Drug: Bupivacaine; Drug: Fentanyl, morphine, hydromorphone, hydrocodone, acetaminophen, ketorolac, gabapentin, ketamine, ibuprofen Sponsors: Andrew A Herring; Oregon Health and Science University; University of California, Los Angeles Unknown status Wed, 08 Aug 2018 12:00:00 EDT Study of Respiratory Depression When Using a Hydromorphone Pain ProtocolConditions: Pain; Respiratory DepressionInterventions: Drug: Hydromorphone; Drug: Usual care group Sponsor: Albert Einstein Healthcare Network Terminated Wed, 06 Feb 2013 12:00:00 EST Oxycodone Extended-release in the Treatment of Perioperative Pain in Patients Undergoing Orthopaedic SurgeryCondition: SurgeryInterventions: Drug: Extended-release oxycodone; Drug: Extended- release Oxycodone; Drug: ketoprofen; Drug: dipirone; Drug: dexametasone; Drug: Morphine IV (rescue) Sponsor: Hospital Central Dr. Luis Ortega Completed Fri, 12 Sep 2014 12:00:00 EDT Continuous Infusion for Pain ReliefConditions: Regional Anesthesia; Caeserian Section; Local AnestheticInterventions: Drug: control group; Drug: infiltration group Sponsor: Tunisian Military Hospital Unknown status Thu, 17 Mar 2016 12:00:00 EDT Effect of Ketorolac on Post Adenotonsillectomy PainCondition: Obstructive Sleep ApneaInterventions: Drug: Ketorolac; Drug: Standard of Care Sponsor: Emory University Recruiting Fri, 16 Mar 2018 12:00:00 EDT Observation of Respiration Following Regional Anaesthesia With Intrathecal Opioids for Caesarean SectionCondition: Respiratory DepressionIntervention: Sponsor: NHS Greater Clyde and Glasgow Completed Tue, 16 Oct 2007 12:00:00 EDT
Intrathecal Atropine to Prevent Postoperative Nausea and VomitingCondition: Postoperative NauseaInterventions: Drug: Intrathecal atropine; Drug: dexamethasone Sponsor: Assiut University Completed Tue, 02 Jan 2018 12:00:00 EST Pectoralis and Serratus Nerves Block in Thoracic SurgeryConditions: Anesthesia; Surgery; Block; Thoracic InjuryInterventions: Drug: Bupivacaine Hydrochloride; Device: Ultrasound; Procedure: Thoracotomy; Drug: Opioids; Drug: NSAID Sponsor: Soroka University Medical Center Unknown status Wed, 18 Jan 2017 12:00:00 EST Safety, Efficacy and Pharmacokinetic Study of Dexmedetomidine in Pediatrics Ages ≥28 Weeks to ≤44 Weeks Gestational AgeCondition: SedationInterventions: Drug: Midazolam; Drug: Fentanyl/Morphine; Drug: Dexmedetomidine Sponsor: Hospira, now a wholly owned subsidiary of Pfizer Completed Fri, 09 Jul 2010 12:00:00 EDT Ibuprofen IV vs Acetaminophen IV for the Treatment of Pain Following Orthopaedic Low Extremity SurgeryConditions: Lower Extremity Problem; Surgery; Postoperative PainInterventions: Drug: Ibuprofen; Drug: Acetaminophen Sponsor: Indonesia University Completed Tue, 11 Dec 2018 12:00:00 EST Do Corticosteroid Injections During Total Knee Replacement Improve Early Clinical Results?Conditions: Osteoarthritis; Post-traumatic; ArthrosisInterventions: Drug: methylprednisolone acetate; Drug: active comparator Sponsors: New Lexington Clinic; St. Joseph's Health Care London Completed Wed, 27 Jun 2007 12:00:00 EDT Effect of Bilateral Transversus Thoracis Muscle Plane Block in Patients Undergoing Coronary Artery Bypass Graft Surgery.Conditions: Coronary Artery Disease; Pain SyndromeIntervention: Procedure: Ultrasound guided Bilateral Transversus Thoracis Muscle Plane block Sponsor: University Hospital, Montpellier Completed Mon, 19 Apr 2021 12:00:00 EDT Ultrasound-guided Transmuscular Quadratus Lumborum Block for Elective Caesarean Section.Condition: Postoperative PainInterventions: Drug: Ropivacaine; Drug: Saline; Drug: Acetaminophen; Drug: Ibuprofen 400Mg Tablet / Celebra 100 Mg tablet; Device: ultrasound-guided nerve block; Drug: Morphine; Device: Patient-controlled analgesia Sponsor: Zealand University Hospital Completed Wed, 01 Mar 2017 12:00:00 EST Behavioral and Neuroimaging Changes After Cognitive Rehab in Traumatic Brain Injuries (TBI) and Mild Cognitive Impairment (MCI)Conditions: Mild Cognitive Impairment; Alzheimer's Disease; Traumatic Brain InjuryInterventions: Behavioral: Mnemonic strategy training (MST); Behavioral: Repeated exposure (XP); Behavioral: Subtracting Cues training Sponsors: VA Office of Research and Development; Emory University Completed Mon, 14 Jul 2008 12:00:00 EDT Levorphanol as a Second Line Opioid in Cancer PatientsConditions: Malignant Neoplasm; Metastatic Malignant NeoplasmInterventions: Drug: Hydrocodone; Drug: Hydromorphone; Drug: Hydromorphone Hydrochloride; Drug: Levorphanol; Drug: Morphine; Drug: Morphine Sulfate; Drug: Oxycodone; Drug: Oxymorphone; Drug: Oxymorphone Hydrochloride; Other: Questionnaire Administration Sponsors: M.D. Anderson Cancer Center; National Cancer Institute (NCI) Recruiting Fri, 06 Jul 2018 12:00:00 EDT Intraoperative Magnesium Sulfate Administration During Orthotopic Liver TransplantationCondition: Postoperative PainInterventions: Drug: isotonic saline; Drug: Magnesium Sulfate Sponsor: Fayoum University Hospital Recruiting Wed, 24 Oct 2018 12:00:00 EDT
the Effect of the Transversus Abdominis Plane (TAP) Block on the Minimal Laparotomy : a Randomized Controlled TrialCondition: Colon CancerIntervention: Procedure: Transversus Abdominis Plane block Sponsor: Kaohsiung Medical University Chung-Ho Memorial Hospital Unknown status Wed, 17 Aug 2011 12:00:00 EDT Sublingual Fentanyl and Procedural Burn PainCondition: Burn PainIntervention: Drug: Sublingual Fentanyl Spray Sponsor: Loyola University Terminated Tue, 16 Sep 2014 12:00:00 EDT Outcomes Of Perioperative Pregabalin On Total Knee ArthroplastyCondition: Pain, PostoperativeInterventions: Drug: pregabalin; Drug: Placebo; Drug: Etoricoxib; Drug: paracetamol; Drug: Morphine; Drug: Ropivacaine Sponsor: National University Hospital, Singapore Completed Thu, 03 Nov 2016 12:00:00 EDT A Comparison of Exparel Local Anesthetic in Total Knee Arthroplasty (TKA) PatientsConditions: Osteoarthritis, Knee; Arthroplasty, Replacement, KneeInterventions: Drug: Liposomal bupivacaine, 266mg; Drug: Bupivacaine 0.5 % with Epinephrine; Drug: Ketorolac 30mg; Drug: Morphine 10mg; Drug: Bupivacaine 0.25% with Epinephrine Sponsor: Holy Cross Hospital, Florida Withdrawn Mon, 09 May 2016 12:00:00 EDT Impact of Intra- and Postoperative Continuous Infusion of Lidocaine on Analgesia in Vascular AnaesthesiaConditions: Abdominal Aorta Aneurysm; Abdominal Aorta Atheroma; Surgery; Pain, PostoperativeInterventions: Drug: lidocaine 10mg/ml; Drug: Placebo; Drug: Metamizole; Drug: Morphine Sponsor: Łukasz Krzych Suspended Thu, 31 Dec 2020 12:00:00 EST Levobupivacaine Prolonged Wound Infusion for Postoperative Pain Relief After Breast SurgeryConditions: Acute Pain; Chronic Pain; Wound Infusion; MastectomyInterventions: Drug: Levobupivacaine PCIA (Patient Controlled Intrawound Analgesia); Drug: saline; Drug: Levobupivacaine continuous infusion; Device: intrawound infusion catheter; Drug: morphine; Drug: Patrol Sponsor: IRCCS Policlinico S. Matteo Unknown status Tue, 14 Jan 2014 12:00:00 EST Non-Inferiority Study to Compare the Effectiveness of the Seldinger Over-the-Wire Technique and the Modified Seldinger TechniqueCondition: Effectiveness and Safety of the Seldinger Wire Technique Using a 145 cm Guidewire With the Modified Seldinger Technique Using a 70 cm GuidewireInterventions: Device: Angiodynamic Bioflo Picc IR-KIT (145 cm guidewire) or; Device: Angiodynamic Bioflo Picc MST-KIT (70 cm guidewire) Sponsor: Jena University Hospital Completed Tue, 10 Mar 2020 12:00:00 EDT Additional Effect of Wound Infiltration After Cesarean Section With Optimal Standard AnalgesiaConditions: Postoperative Pain; Anesthesia, Local; Breast FeedingIntervention: Device: Continuous wound infiltration Sponsor: Poissy-Saint Germain Hospital Completed Mon, 17 Dec 2012 12:00:00 EST Ultrasound-guided Blocks for Ambulatory Knee ArthroscopyConditions: Postoperative Pain; Postoperative Nausea and Vomiting; Postoperative Function LevelInterventions: Procedure: Block of the SN and ONP; Procedure: Placebo block; Drug: Paracetamol; Drug: Morphine; Drug: Ondansetron; Drug: Metoclopramide Sponsor: Jens Borglum Neimann Completed Tue, 23 Apr 2013 12:00:00 EDT Mu-Opioid Receptor Genetic Polymorphism and Intrathecal AnalgesiaConditions: Labor Pain; Post-cesarean DeliveryIntervention: Procedure: Blood Draw Sponsor: Northwestern University Completed Thu, 04 Jan 2007 12:00:00 EST
Sublingual Sufentanil Tablet System (SSTS) Versus Intravenous Patient Controlled Analgesia After Back Surgery.Condition: Pain, PostoperativeInterventions: Device: Sublingual sufentanil tablet system; Drug: Patient-controlled intravenous analgesia Sponsors: University Hospital, Antwerp; Universiteit Antwerpen Completed Mon, 30 Jan 2017 12:00:00 EST Multimodal Drug Infiltration in Total Knee Arthroplasty: Is Posterior Capsular Infiltration Worth the Risk?Condition: Osteoarthritis, KneeInterventions: Drug: 0.5% bupivacaine 100 mg, morphine sulfate 5 mg, 0.1% epinephrine 0.6 mg, and ketorolac 30 mg mixed NSS up to 100 mL; Procedure: Drug injection at Anterior soft tissue (25 mL)+Medial gutter area (25 mL)+Lateral gutter area (25 mL)+Posterior capsular infiltration (25 mL); Procedure: Drug injection at Anterior soft tissue (34 mL)+Medial gutter area (33 mL)+Lateral gutter area (33 mL Sponsors: Thammasat University; Krit Boontanapibul Completed Wed, 10 Aug 2016 12:00:00 EDT Opioid-Free Anesthesia in Cardiac SurgeryCondition: AnesthesiaInterventions: Drug: Dexmédétomidine 0.5 g/kg + lidocaine 1.5 mg/kg; Drug: Remifentanil Sponsor: University Hospital, Rouen Not yet recruiting Fri, 25 Jun 2021 12:00:00 EDT Study of Opioid Immunosuppressive EffectsCondition: Opioid Abuse or DependenceIntervention: Sponsor: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University Unknown status Thu, 20 Jun 2013 12:00:00 EDT The Influence of Peripheral Nerve Blocks in Patients Undergoing Limb Orthopedic SurgeryConditions: Pain, Postoperative; Change; Circulatory; Surgical InjuryIntervention: Procedure: 0.25% bupivacaine Sponsors: Kaohsiung Medical University Chung-Ho Memorial Hospital; Kaohsiung Municipal Hsiaokang Hospital Completed Fri, 12 Apr 2019 12:00:00 EDT Incidence of Respiratory Depression in Cesarean SectionConditions: Respiratory Depression; Postoperative PainIntervention: Sponsors: Wake Forest University; Forsyth Medical Center Terminated Fri, 13 Aug 2010 12:00:00 EDT Local Anesthetic Continuous Preperitoneal Infiltration and Wound HyperalgesiaCondition: Pain, PostoperativeInterventions: Drug: continuous ropivacaine preperitoneal infusion; Drug: intravenous lidocaine infusion; Drug: parenteral analgesia combining acetaminophen and morphine; Drug: NaCl Sponsor: Assistance Publique - Hôpitaux de Paris Completed Mon, 01 Mar 2010 12:00:00 EST Exploring the Immune Response to SARS-CoV-2 COVID-19 Vaccines in Patients With Relapsing Multiple Sclerosis (RMS) Treated With OfatumumabCondition: Multiple SclerosisIntervention: Drug: Ofatumumab Sponsor: Novartis Pharmaceuticals Recruiting Mon, 03 May 2021 12:00:00 EDT Pecto-Intercostal Fascial Block vs. Transversus Thoracic Muscle Plane Block in Cardiac SurgeryConditions: Pain, Postoperative; Coronary Artery DiseaseInterventions: Procedure: Single-injection, ultrasound-guided bilateral PIF block.; Procedure: Single-injection, ultrasound-guided bilateral TTMP block. Sponsor: Ondokuz Mayıs University Completed Wed, 10 Mar 2021 12:00:00 EST A Study of Dose-response Relationship and the Evidence Based Multisensory Stimulation InterventionConditions: Psychotic Disorders; Anxiety; Complementary Therapies; Clinical TrialIntervention: Behavioral: multisensory stimulation therapy Sponsors: Jianan Psychiatric Center, Ministry of Health and Welfare; Taiwan Nurses Association; National Cheng Kung University Completed Thu, 19 Aug 2021 12:00:00 EDT
Consumer Understanding and Use of Medication GuidesCondition: Revised Medication Guide FormatsIntervention: Sponsors: Northwestern University; Abbott Completed Wed, 21 Nov 2012 12:00:00 EST Individualized Analgesia After AdenotonsillectomyCondition: AnalgesiaInterventions: Drug: Individualized opioid analgesia; Device: conventional opioid analgesia Sponsor: Children's Hospital of Fudan University Completed Tue, 13 Dec 2016 12:00:00 EST Dose Escalation of Dexamethasone to Increase Duration of Transversus Abdominal Plane Block Following Cesarean SectionCondition: Post Surgical PainInterventions: Drug: 2mg Dexamethasone; Drug: 4mg Dexamethasone; Drug: Ropivacaine (TAP blocks); Drug: Morphine; Drug: Bupivacaine Hydrochloride; Drug: Normal saline 1ml; Drug: Normal saline 0.5ml Sponsor: University of Alabama at Birmingham Terminated Fri, 31 Mar 2017 12:00:00 EDT Femoral Preincisional Block in Acute Postoperative Pain Management of Surgery Orthopaedic Lower LimbCondition: SurgeryInterventions: Procedure: Femoral block by ultrasound and neurostimulation; Drug: Intravenous analgesia Sponsor: Hospital Central Dr. Luis Ortega Completed Fri, 12 Sep 2014 12:00:00 EDT Shaping Anesthetic Techniques to Reduce Post-operative DeliriumConditions: Delirium; Lumbar Radiculopathy; Lumbar Osteoarthritis; Lumbar Spine Disc DegenerationInterventions: Procedure: Light sedation with propofol; Procedure: Induction with propofol; Procedure: Maintenance anesthetic using a volatile anesthetic; Procedure: Muscle relaxant during maintenance anesthesia; Procedure: Pain control with fentanyl; Procedure: Bispectral Index (BIS) monitoring for depth of anesthesia; Procedure: Spinal Anesthesia; Procedure: Midazolam administered during spinal anesthesia; Procedure: Cerebrospinal fluid collection; Procedure: Administration of intrathecal morphine Sponsors: Johns Hopkins University; Mercy Medical Center Completed Fri, 28 Apr 2017 12:00:00 EDT Quadratus Lumborum Block : Effect on Acute Pain and Quality of Recovery After Laparoscopic Renal SurgeryConditions: Laparoscopic Renal Surgery; Pain Management; Nerve BlockInterventions: Procedure: single-injection QLB(quadratus lumborum block); Device: Philip CX50 Ultrasound Scanner; Device: PAJUNK StimuLong; Drug: single dose ropivacaine; Drug: Morphine given as IPCA(intravenous patient controlled analgesia) Sponsor: Cui Xulei Completed Fri, 22 Jul 2016 12:00:00 EDT Continuous Lornoxicam Infusion for Orthopaedic SurgeryCondition: Closed Non Comminuted Long Bone FracturesInterventions: Drug: Placebo; Drug: Continuous infusion; Drug: Scheduled Sponsor: Mansoura University Suspended Wed, 31 Oct 2012 12:00:00 EDT PENG Block for Traumatic Hip Fracture in the Emergency DepartmentConditions: Hip Fractures; Acute Pain; Emergency DepartmentIntervention: Procedure: Ultrasound-guided Pericapsular Nerve Group (PENG) Block Sponsors: Dalin Tzu Chi General Hospital; Far Eastern Memorial Hospital Enrolling by invitation Tue, 10 Aug 2021 12:00:00 EDT Abciximab (ReoPro) as a Therapeutic Intervention for Sickle Cell Vaso-Occlusive Pain CrisisConditions: Sickle Cell Disease; Hb-SS Disease With Vasoocclusive Pain; Hemoglobin SS Disease With Vasoocclusive Crisis; Other Sickle Cell Disease With Vaso-Occlusive Pain; Hemoglobin SS Disease With CrisisInterventions: Drug: Abciximab; Drug: Placebo; Other: Intravenous hydration; Drug: Ibuprofen; Drug: Parenteral narcotic; Other: Incentive spirometry; Other: Supplemental oxygen Sponsors: St. Louis University; Janssen Services, LLC Withdrawn Fri, 30 Aug 2013 12:00:00 EDT 50 Hz vs. 25 Hz Magnetic Seizure Therapy for SchizophreniaCondition: SchizophreniaInterventions: Procedure: 25 Hz magnetic seizure therapy; Procedure: 50 Hz magnetic seizure therapy Sponsor: Shanghai Mental Health Center Completed Mon, 26 Dec 2016 12:00:00 EST
Next Generation Personalized Neuroblastoma TherapyConditions: Neuroblastoma; CancerInterventions: Procedure: Biopsy; Genetic: Next Generation Sequencing; Procedure: Tumor Scans; Procedure: Bone marrow Tests; Other: Physical Exam; Other: Eye Exam; Other: Labs; Other: Pregnancy Test; Behavioral: Interviews; Other: ECG; Other: Echocardiogram; Drug: Ribociclib; Drug: Ceritinib Sponsors: Yael P Mosse; Novartis Pharmaceuticals; Foundation Medicine Recruiting Mon, 23 May 2016 12:00:00 EDT Optimal Dose of Prophylactic Naloxone in Reducing Opioid-Induced Side Effects in Children/AdolescentsConditions: Pain; Nausea; PruritusIntervention: Drug: naloxone Sponsor: Johns Hopkins University Completed Fri, 26 May 2006 12:00:00 EDT Pharmacologic Impact on Sedation AssessmentsCondition: Pediatric Acute Lung InjuryIntervention: Other: Pharmacokinetic Sampling and pharmacogenetic analysis Sponsors: Children's Hospital of Philadelphia; National Heart, Lung, and Blood Institute (NHLBI) Completed Fri, 16 Apr 2010 12:00:00 EDT Periarticular Multimodal Drug Injections in Total Knee ArthroplastyCondition: Osteoarthritis, KneeInterventions: Drug: ropivacaine; Drug: morphine sulfate; Drug: ketorolac; Drug: epinephrine; Drug: cefuroxime Sponsor: Seoul National University Hospital Completed Thu, 14 May 2009 12:00:00 EDT Local Anesthetic Wound Infusion and Functional Recovery After Colon SurgeryConditions: Colon Cancer; Inflammatory Bowel Diseases; DiverticulitisInterventions: Procedure: Epidural analgesia; Procedure: Wound catheter Sponsor: Franco Carli Terminated Thu, 04 Feb 2010 12:00:00 EST Effectiveness of Intraoperative Exparel for Postoperative Pain Control in Total Knee ArthroplastyConditions: Osteoarthritis; Total Knee Arthroplasty; Pain ManagementInterventions: Drug: Pain Cocktail with Exparel; Drug: Pain Cocktail with Ropivacaine Sponsor: DeClaire LaMacchia Orthopaedic Institute Unknown status Wed, 22 Jun 2016 12:00:00 EDT A Comparison Study Between Ketamine Versus Tramadol for Pain Management After Major Upper Abdominal SurgeryCondition: Postoperative PainInterventions: Drug: Tramadol; Drug: Ketamine Sponsor: Attikon Hospital Completed Thu, 16 Jul 2015 12:00:00 EDT Post-Op Pain Control for Prophylactic Intramedullary Nailing.Conditions: Bone Metastases; Lymphoma; Multiple Myeloma; Opioid Use; PainInterventions: Drug: Ketorolac; Drug: Normal saline; Drug: Acetaminophen; Drug: Oxycodone Acetaminophen; Drug: Morphine; Drug: Hydrocodone/Acetaminophen; Drug: Oxycodone Sponsor: St. Louis University Recruiting Wed, 30 Jan 2019 12:00:00 EST Impact of Pregabalin in Chronic Users vs. a Perioperative Limited Prescription on Oxycodone RequirementConditions: Postoperative Pain; Neuropathic PainInterventions: Drug: Pregabalin; Other: Naive patient Sponsors: Christophe Aveline, MD; Rennes University Hospital Completed Mon, 15 Aug 2016 12:00:00 EDT A Multicentre Study of the Efficacy and Safety of Supplementary Treatment With Cholecalciferol in Patients With Relapsing Multiple Sclerosis Treated With Subcutaneous Interferon Beta-1a 44 µg 3 Times WeeklyCondition: Multiple SclerosisInterventions: Dietary Supplement: Cholecalciferol (Vitamin D3); Dietary Supplement: Placebo; Drug: Rebif Sponsors: Merck KGaA, Darmstadt, Germany; Merck Serono S.A.S, France Completed Thu, 09 Sep 2010 12:00:00 EDT
Post Operative Pain Control After Pediatric Hip SurgeryConditions: Hip Surgery; Post Operative Pain ControlInterventions: Procedure: Lumbar Plexus Catheter; Procedure: Lumbar Epidural Catheter; Procedure: Patient Controlled Analgesia; Drug: Fentanyl; Drug: Morphine; Drug: Lorazepam; Drug: Ondansetron; Drug: Diphenhydramine; Drug: Acetaminophen; Drug: Oxycodone; Drug: Ropivacaine Sponsors: Seattle Children's Hospital; Seattle Children's Research Institute Center for Clinical and Translational Research Completed Mon, 19 Feb 2018 12:00:00 EST OCT Guided Magmaris RMS in STEMICondition: STEMIIntervention: Device: Magmaris resorbable magnesium scaffold Sponsors: Universitaire Ziekenhuizen Leuven; Centre Hospitalier Universitaire Saint Pierre; Universitair Ziekenhuis Brussel; CHU de Charleroi; Jolimont; Ziekenhuis Oost-Limburg; University Hospital St Luc, Brussels; Centre Hospitalier Universitaire Dinant Godinne - UCL Namur; Le centre hospitalier EpiCURA; Centre Hospitalier Régional de la Citadelle Recruiting Mon, 20 May 2019 12:00:00 EDT Pharmacokinetics of Sedatives and Analgesics During Extracorporeal Membrane Oxygenation (ECMO) SupportCondition: Drug EffectInterventions: Drug: Dexmedetomidine; Drug: Fentanyl; Drug: Midazolam; Drug: Morphine Sponsor: Boston Children's Hospital Recruiting Fri, 20 Jul 2018 12:00:00 EDT Intrathecal Magnesium and Postoperative AnalgesiaCondition: Total Hip ReplacementIntervention: Drug: intrathecal magnesium sulfate Sponsor: University Hospital, Clermont-Ferrand Completed Mon, 19 Nov 2007 12:00:00 EST Evaluation of the Efficacy of Intra-nasal Sufentanil for Analgesia of Vaso-occlusive Crisis in Sickle-cell Adults.Condition: Sickle Cell CrisisInterventions: Drug: Sufentanil; Drug: EMONO Sponsor: University Hospital, Bordeaux Not yet recruiting Tue, 03 Sep 2019 12:00:00 EDT Multimodal Narcotic Limited Perioperative Pain Control With Colorectal SurgeryConditions: Colon Cancer; Colon Diverticulosis; Colonic Neoplasms; Colonic Diverticulitis; Pain, Postoperative; Ileus; Ileus Paralytic; Ileus; Mechanical; Constipation Drug Induced; Constipation; Rectum Cancer; Rectum NeoplasmInterventions: Drug: Acetaminophen; Drug: Gabapentin; Drug: Orphenadrine; Drug: Lidocaine; Drug: Marcaine; Drug: Ketamine; Drug: Methadone; Drug: Tramadol; Drug: Ketorolac; Drug: Morphine Sulfate; Drug: Fentanyl; Drug: Dilaudid; Drug: Hydrocodone-Acetaminophen Tab 5-325 MG; Drug: HYDROCODONE/ACETAMINOPHEN 5 Mg-325 Mg ORAL TABLET Sponsor: University of Illinois College of Medicine at Peoria Unknown status Tue, 08 Nov 2016 12:00:00 EST Open-Label, Safety, and Efficacy Study of Dexmedetomidine in Preterm Subjects Ages ≥28 Weeks to <36 Weeks Gestational AgeCondition: AnesthesiaInterventions: Drug: Dexmedetomidine; Drug: Midazolam; Drug: Fentanyl; Drug: Morphine Sponsor: Hospira, now a wholly owned subsidiary of Pfizer Completed Thu, 12 Jan 2012 12:00:00 EST Perioperative Opioid-induced Hyperalgesia and Its Prevention With Ketamine and MethadoneConditions: Post Operative Pain; HyperalgesiaInterventions: Drug: ketamine infusion; Drug: Methadone PCA Sponsor: Fondazione IRCCS Istituto Nazionale dei Tumori, Milano Unknown status Tue, 08 May 2012 12:00:00 EDT How Does Gabapentin Affects Post-operative Tonsillectomy Pain?Condition: Post-operative PainInterventions: Drug: Gabapentin; Drug: Placebo Sponsor: University of British Columbia Completed Wed, 27 Feb 2008 12:00:00 EST Effects of Buprenorphine/Naloxone Dose on Experimental Stress Reactivity and Opioid AbstinenceConditions: Heroin Dependence; Opioid Use DisorderInterventions: Drug: Extended release morphine; Drug: Buprenorphine/Naloxone low dose; Drug: Buprenorphine/Naloxone moderate dose; Drug: Buprenorphine/Naloxone high dose; Drug: Active stressor; Drug: Placebo stressor Sponsor: Wayne State University Completed Tue, 10 Jan 2017 12:00:00 EST
Innovative Delivery of Evidence Based Psychotherapy to Women With Military Sexual TraumaConditions: PTSD; Stress Disorders, Post - Traumatic; Anxiety Disorders; Mental Disorders; Stress Disorders, TraumaticIntervention: Behavioral: PE Sponsors: Medical University of South Carolina; Charleston Research Institute Completed Wed, 15 Apr 2015 12:00:00 EDT Study Evaluating Safety and Efficacy of Dexmedetomidine (DEX) in Intubated and Mechanically Ventilated Pediatric Intensive Care Unit (PICU) SubjectsCondition: SedationInterventions: Drug: Dexmedetomidine; Drug: Midazolam; Drug: Fentanyl; Drug: Morphine Sponsor: Hospira, now a wholly owned subsidiary of Pfizer Completed Fri, 03 Apr 2009 12:00:00 EDT An Open Label Extension Study of Ublituximab in Subjects With Relapsing Multiple SclerosisCondition: Relapsing Multiple Sclerosis (RMS)Intervention: Biological: Ublituximab Sponsor: TG Therapeutics, Inc. Enrolling by invitation Fri, 18 Oct 2019 12:00:00 EDT Efficacy and Safety of IRE for RMsCondition: Kidney CancerIntervention: Device: Nano Knife Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) Unknown status Mon, 24 Nov 2014 12:00:00 EST Thoracic Paravertebral Block : Effect on Acute Pain and Chronic Pain of Hepatectomy With Right J-shape Subcostal IncisionConditions: Hepatectomy; Analgesia; Nerve BlockInterventions: Procedure: single-injection TPVB + continuous TPVB; Device: Philip CX50 Ultrasound Scanner; Device: PAJUNK Contiplex S Catheter; Drug: single dose ropivacaine; Drug: continuously infusion of ropivacaine; Drug: Morphine given as IPCA Sponsor: Cui Xulei Completed Wed, 29 Jun 2016 12:00:00 EDT Study of Evobrutinib in Participants With RMS (evolutionRMS 2)Condition: Relapsing Multiple SclerosisInterventions: Drug: Evobrutinib; Drug: Placebo (match to Teriflunomide); Drug: Teriflunomide; Drug: Placebo (match to Evobrutinib) Sponsors: Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany; EMD Serono Research & Development Institute, Inc. Active, not recruiting Wed, 08 Apr 2020 12:00:00 EDT Study of Evobrutinib in Participants With RMS (evolutionRMS 1)Condition: Relapsing Multiple SclerosisInterventions: Drug: Evobrutinib; Drug: Placebo (match to Teriflunomide); Drug: Teriflunomide; Drug: Placebo (match to Evobrutinib) Sponsors: Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany; EMD Serono Research & Development Institute, Inc. Active, not recruiting Wed, 08 Apr 2020 12:00:00 EDT Dexmedetomidine Supplemented Analgesia in Patients at High-risk of Obstructive Sleep ApneaConditions: Obstructive Sleep Apnea; Analgesia; Dexmedetomidine; High-flow Nasal Cannula; Sleep QualityInterventions: Drug: Dexmedetomidine; Drug: Placebo Sponsor: Peking University First Hospital Recruiting Thu, 29 Oct 2020 12:00:00 EDT Phenylephrine Versus Norepinephrine for Maintenance of Hemodynamic During Cesarean Section Under Spinal AnesthesiaConditions: Cesarean Section Complications; Spinal AnesthesiaInterventions: Drug: Norepinephrine; Drug: Phenylephrine Sponsor: Centre Hospitalier Régional d'Orléans Completed Thu, 21 Feb 2019 12:00:00 EST Postoperative Pain Management in Patients Undergoing Intramedullary Nail Fixation After Tibia and Femoral FracturesConditions: Femur Fracture; Tibial FracturesIntervention: Other: Use of non-steroid anti-inflammatory drugs (NSAIDS) as an alternative for post-operative pain management after a femur and tibia fracture Sponsor: University of Puerto Rico Not yet recruiting Thu, 18 Feb 2021 12:00:00 EST
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