Clinical Trials

Spinal Morphine for Patients With Obstructive Sleep Apnea

Condition:   Obstructive Sleep Apnea
Interventions:   Drug: Intrathecal Morphine;   Drug: No Intrathecal Morphine
Sponsor:   University Health Network, Toronto
Suspended

Wed, 13 Feb 2013 12:00:00 EST

Morphine in Moderate Obstructive Sleep Apnoea

Condition:   Obstructive Sleep Apnoea
Intervention:   Drug: Morphine sulphate
Sponsor:   Papworth Hospital NHS Foundation Trust
Terminated

Tue, 25 Apr 2017 12:00:00 EDT

Nebulized Morphine in Chest Trauma Patients: A Prospective Study

Condition:   Blunt Injury of Thorax
Intervention:   Drug: Morphine (+)
Sponsor:   University Hospital, Mahdia
Completed

Mon, 09 Jul 2018 12:00:00 EDT

A Comparison of Morphine and Morphine Plus Dexmedetomidine in Chronic Cancer Pain

Condition:   Chronic Pain
Interventions:   Drug: Morphine;   Drug: Morphine plus dexmedetomidine
Sponsor:   Cukurova University
Completed

Thu, 13 Nov 2014 12:00:00 EST

Comparison for Pethidine Requirement in Patients Received Spinal Morphine 0.2 and 0.3 mg for Post Lobectomy Analgesia

Conditions:   Solitary Mass;   Lung Diseases
Interventions:   Drug: spinal morphine 0.3 mg;   Drug: spinal morphine 0.2 mg
Sponsor:   Mahidol University
Completed

Mon, 08 Nov 2010 12:00:00 EST

The Effect of Neuraxial Morphine (Duramorph) on Pain Control

Condition:   Perineal Tear
Intervention:   Drug: Morphine.
Sponsor:   Augusta University
Recruiting

Wed, 24 Apr 2019 12:00:00 EDT

Intravenous Remifentanil Plus Morphine or Morphine Alone for Postthoracotomy Pain

Condition:   Pain
Intervention:   Drug: Remifentanil+morphine
Sponsor:   Cukurova University
Completed

Fri, 12 Apr 2013 12:00:00 EDT

Optimal Morphine Dosing Schedule for Neonatal Abstinence Syndrome

Conditions:   Neonatal Abstinence Syndrome;   Neonatal Opioid Withdrawal;   Neonatal Opioid Withdrawal Syndrome
Interventions:   Drug: Morphine PRN;   Drug: Morphine scheduled
Sponsor:   Indiana University
Recruiting

Fri, 06 Mar 2020 12:00:00 EST

Effect of Intrathecal Morphine in Children Undergoing Major Abdominal Surgeries,

Condition:   Major Abdominal Surgeries
Intervention:   Drug: Intrathecal Morphine
Sponsor:   Assiut University
Unknown status

Thu, 18 May 2017 12:00:00 EDT

Therapeutic Rest to Delay Admission in Early Labor: A Prospective Study on Morphine Sleep

Conditions:   Labor Pain;   Early Labor
Intervention:   Drug: Morphine Sulfate and Promethazine
Sponsor:   University of California, San Francisco
Completed

Tue, 29 May 2018 12:00:00 EDT

Acupuncture Versus Intravenous Morphine in the Management of Acute Pain in the Emergency Department

Condition:   Acute Pain
Interventions:   Procedure: Acupuncture;   Drug: Morphine titration
Sponsor:   University of Monastir
Completed

Wed, 03 Jun 2015 12:00:00 EDT

Evaluation of Risk Minimization, Assessment and Outcomes in Patients With Chronic Pain Taking Avinza

Condition:   Pain
Intervention:   Drug: morphine sulfate extended release capsules
Sponsor:   Pfizer
Completed

Thu, 20 Mar 2008 12:00:00 EDT

Ultrasound Guided QLB III Versus Intrathecal Morphine for Analgesia After Cesarean Section

Condition:   Block
Interventions:   Drug: Morphine;   Drug: Quadratus lumborum block
Sponsor:   University Tunis El Manar
Completed

Mon, 12 Feb 2018 12:00:00 EST

Association Between Clinical Effect of Morphine With PCA After Surgery and Pharmacogenetics

Conditions:   Anesthesia;   Surgery
Intervention:   Drug: morphine chlorhydrate
Sponsor:   IRCCS Policlinico S. Matteo
Completed

Wed, 03 Nov 2010 12:00:00 EDT

Is Analgesic Effect of Low Dose Ketamine-midazolam the Same as Morphine

Condition:   Closed Multiple Fractures of Upper and Lower Limbs
Interventions:   Drug: Ketamine-midazolam;   Drug: Morphine
Sponsor:   Isfahan University of Medical Sciences
Completed

Fri, 08 Mar 2013 12:00:00 EST

Intrathecal Morphine Versus Epidural Extended Release Morphine for Pediatric Patients Undergoing Spinal Fusion

Conditions:   Pain Management;   Spinal Fusion;   Scoliosis
Interventions:   Drug: Intrathecal morphine;   Drug: Extended Release Epidural Morphine
Sponsor:   University of Colorado, Denver
Completed

Tue, 14 Apr 2009 12:00:00 EDT

Effect of Locally Administered Morphine and Bupivicaine on Acute and Chronic Postmastectomy Pain

Conditions:   Acute Pain;   Chronic Pain
Intervention:   Drug: local instillation of morphine to surgical wound
Sponsor:   Assiut University
Completed

Thu, 04 Jun 2015 12:00:00 EDT

Intraosseous Morphine in Primary TKA

Conditions:   Knee Disease;   Arthritis Knee;   Pain, Acute
Intervention:   Drug: Morphine
Sponsor:   The Methodist Hospital Research Institute
Completed

Thu, 14 May 2020 12:00:00 EDT

Comparing the Analgesic Effect of Intravenous Acetaminophen and Morphine on Patients With Renal Colic Pain Reffering to the Emergency Department: A Randomized Controlled Trial

Condition:   Renal Colic
Interventions:   Drug: Acetaminophen;   Drug: Morphine
Sponsor:   Seyed Mehdi Pourafzali
Completed

Wed, 24 Jul 2013 12:00:00 EDT

Trial Comparing Intrathecal Morphine With Placebo In Patients Undergoing Robotic Cardiac Surgery

Condition:   Pain
Interventions:   Drug: Intrathecal morphine;   Drug: Placebo
Sponsor:   University of Chicago
Completed

Mon, 07 Aug 2017 12:00:00 EDT

Development of a Morphine Pharmacokinetic and Pharmacodynamic Model for the Neonatal Population

Conditions:   Pain;   Drug Effect
Intervention:   Drug: Morphine
Sponsor:   The Hospital for Sick Children
Withdrawn

Mon, 30 Jan 2017 12:00:00 EST

Study to Examine Pain Relief With Supplemental Intrathecal Morphine in TKA Patients

Condition:   Acute Pain
Interventions:   Drug: Morphine;   Drug: Placebo
Sponsor:   Stony Brook University
Unknown status

Thu, 03 Dec 2015 12:00:00 EST

The Effect of Adding Nalbuphine to Intrathecal Morphine on Analgesic Efficacy and Side Effects After Cesarean Section

Condition:   Postoperative Pain
Interventions:   Drug: Morphine;   Drug: Morphine plus Nalbuphine
Sponsor:   Abdelrady S Ibrahim, MD
Completed

Wed, 23 Mar 2016 12:00:00 EDT

Oxcarbazepine Plus Morphine in Patients With Refractory Cancer Pain

Condition:   Cancer
Interventions:   Drug: Morphine;   Drug: Oxcarbazepine
Sponsor:   Costantine Albany
Terminated

Wed, 05 Mar 2014 12:00:00 EST

Morphine In Acute Myocardial Infarction

Condition:   Acute Myocardial Infarction
Interventions:   Drug: morphine chlorhydrate;   Drug: saline solution
Sponsors:   French Cardiology Society;   Institut National de la Santé Et de la Recherche Médicale, France
Completed

Mon, 23 Aug 2010 12:00:00 EDT

Titrated Versus High and Low Dose Nebulized Morphine to Reduce Pain in Emergency Settings

Conditions:   Post-Traumatic Headache;   Acute Pain
Interventions:   Drug: IV titrated morphine;   Drug: Low dose nebulised morphine;   Drug: High dose nebulised morphine
Sponsor:   University of Monastir
Completed

Fri, 25 Jul 2014 12:00:00 EDT

Spinal Morphine for Postoperative Analgesia in Urology

Condition:   Pain, Postoperative
Intervention:   Drug: Morphine
Sponsor:   Charles University, Czech Republic
Completed

Tue, 18 Sep 2018 12:00:00 EDT

Treatment of Neonatal Abstinence Syndrome With Clonidine Versus Morphine as Primary Therapy

Condition:   Neonatal Abstinence Syndrome
Interventions:   Drug: Clonidine;   Drug: Morphine Sulfate
Sponsor:   The Cooper Health System
Recruiting

Mon, 27 Mar 2017 12:00:00 EDT

0.15 mg Spinal Morphine vs. no Treatment for Morphine Requirement After VATs.

Condition:   Postoperative Pain
Intervention:   Drug: Spinal morphine
Sponsor:   Mahidol University
Unknown status

Fri, 08 Nov 2013 12:00:00 EST

Comparative Bioavailability Study of Morphine Sulfate Immediate Release and Controlled Release

Condition:   Pain
Intervention:   Drug: morphine sulfate
Sponsor:   Roxane Laboratories
Completed

Wed, 14 Oct 2009 12:00:00 EDT

Spinal Morphine Provides an Effective Pain Control in Patients Undergoing Transurethral Resection of Prostate Gland

Conditions:   Spinal Anesthesia;   Transurethral Resection of Prostate;   Analgesia
Interventions:   Drug: Morphine;   Drug: Placebo
Sponsor:   Mahidol University
Completed

Mon, 01 Jun 2015 12:00:00 EDT

Evaluation of Peripheral Itch Mechanisms Following Injection of Morphine

Conditions:   Morphine;   Histamine;   Cowhage;   Isotonic Saline
Intervention:   Drug: Morphine
Sponsor:   Aalborg University
Recruiting

Thu, 17 Dec 2020 12:00:00 EST

0.05 mg Versus 0.1 mg Spinal Morphine for Reducing Morphine Requirement After Vaginal Hysterectomy

Condition:   Pain
Intervention:   Drug: Morphine
Sponsor:   Mahidol University
Unknown status

Thu, 04 Mar 2010 12:00:00 EST

Morphine Versus Morphine-promethazine Combination for Acute Low Back Pain Relief in the Adult Emergency Department

Condition:   Low Back Pain
Interventions:   Drug: Morphine-Promethazine;   Drug: morphine
Sponsor:   Tel-Aviv Sourasky Medical Center
Unknown status

Tue, 25 May 2010 12:00:00 EDT

0.05 Versus 0.1 mg Spinal Morphine for Reducing Morphine Requirement After Vaginal Hysterectomy

Conditions:   Pain;   Vaginal Hysterectomy
Interventions:   Drug: Spinal morphine 0.05 mg;   Drug: Spinal morphine 0.1 mg
Sponsor:   Mahidol University
Unknown status

Wed, 03 Mar 2010 12:00:00 EST

Efficacy of Injectable Fentanyl in Sublingual Route Versus Oral Morphine Syrup for Breakthrough Pain

Condition:   Pain, Breakthrough
Interventions:   Drug: Fentanyl Citrate 50Mcg/Ml Inj_#1;   Drug: Morphine
Sponsor:   Rajavithi Hospital
Recruiting

Wed, 08 Sep 2021 12:00:00 EDT

Genetic Variation in Organic Cation Transport 1 (OCT1) and Its Significance for Morphine Pharmacokinetics

Conditions:   Organic Cation Transporter 1;   Morphine
Intervention:   Drug: Morphine
Sponsors:   University of Southern Denmark;   Danish Council for Independent Research;   The Faculty of Health Sciences SDU;   Region of Southern Denmark
Completed

Wed, 07 Feb 2018 12:00:00 EST

Intravenous Lidocaine Versus Morphine for Severe Pain in the ED

Condition:   Pain
Interventions:   Drug: Intravenous lidocaine;   Drug: Intravenous morphine
Sponsor:   Alameda Health System
Completed

Fri, 23 Sep 2016 12:00:00 EDT

Spinal Morphine vs. Hydromorphone for Pain Control After Cesarean Delivery

Conditions:   Analgesia, Obstetrical;   Obstetric Surgical Procedures
Interventions:   Drug: Morphine;   Drug: Hydromorphone
Sponsor:   Mayo Clinic
Completed

Fri, 03 Jun 2016 12:00:00 EDT

Adding Nalbuphine for Control of Intrathecal Morphine Pruritus

Conditions:   Pruritus;   Pain, Postoperative;   Nausea, Postoperative;   Vomiting, Postoperative
Interventions:   Drug: Morphine 10 MG/ML;   Drug: Nalbuphine Hydrochloride 10 MG/ML
Sponsor:   Minia University
Recruiting

Mon, 19 Oct 2020 12:00:00 EDT

Association Between Clinical Effect of Continuous Morphine Administration After Surgery and Pharmacogenetics

Conditions:   Anesthesia;   Surgery
Intervention:   Drug: morphine chlorhydrate
Sponsor:   IRCCS Policlinico S. Matteo
Withdrawn

Wed, 03 Nov 2010 12:00:00 EDT

Intranasal Fentanyl Versus Intravenous Morphine in the Treatment of Severe Painful Sickle Cell Crises in Children

Conditions:   Pain;   Sickle Cell Disease
Interventions:   Drug: Fentanyl Citrate;   Drug: Morphine sulphate
Sponsors:   University College Dublin;   National Children's Research Centre;   Our Lady's Children's Hospital, Crumlin
Completed

Mon, 24 Sep 2018 12:00:00 EDT

Labour Analgesia; Comparing a Combinations of Either Fentanyl or Bupivacaine With Intrathecal Morphine

Condition:   Labor Pain
Interventions:   Drug: Intrathecal morphine with fentanyl;   Drug: Intrathecal morphine with bupivacaine
Sponsor:   Makerere University
Completed

Wed, 15 Jul 2015 12:00:00 EDT

Epidural Morphine Following Vaginal Delivery

Condition:   Pain
Interventions:   Drug: Preservative-free epidural morphine;   Drug: Placebo
Sponsors:   Mount Sinai Hospital, Canada;   The Physicians' Services Incorporated Foundation
Completed

Fri, 05 Dec 2008 12:00:00 EST

Effect of Morphine on Dyspnea and 6-Minute Walk Distance in Pulmonary Arterial Hypertension

Condition:   Pulmonary Arterial Hypertension
Intervention:   Drug: Morphine Sulfate
Sponsor:   John Granton
Unknown status

Wed, 17 Jan 2018 12:00:00 EST

Ibuprofen Compared to Morphine as a Pediatric Postoperative Pain Management Tool Following Inguinal Surgery

Condition:   Inguinal Surgery
Interventions:   Drug: Ibuprofen;   Drug: Morphine
Sponsors:   McMaster University;   McMaster Surgical Associates
Recruiting

Fri, 13 Nov 2015 12:00:00 EST

Study of Oral Morphine Sulfate Administration in Pediatric Subjects

Condition:   Pain, Postoperative
Intervention:   Drug: Morphine Sulfate
Sponsors:   West-Ward Pharmaceutical;   Premier Research International LLC
Completed

Mon, 12 Feb 2018 12:00:00 EST

Efficacy Study of Nebulized Morphine and Intravenous Morphine in Post Traumatic Pain

Condition:   Post Traumatic Pain
Interventions:   Drug: nebulized morphine;   Drug: Intravenous morphine
Sponsor:   University of Monastir
Completed

Fri, 14 May 2010 12:00:00 EDT

Epidural Morphine Versus Epidural Fentanyl Infusion Following Cesarean Section

Condition:   Pain
Interventions:   Drug: Preservative free morphine;   Drug: Fentanyl
Sponsor:   Goodman, Evan, M.D.
Unknown status

Wed, 01 Jun 2011 12:00:00 EDT

Decreased Neuraxial Morphine After Cesarean Delivery

Condition:   Anesthesia
Interventions:   Drug: Morphine Sulfate 150 mcg;   Drug: Morphine Sulfate 50mcg
Sponsor:   University of Alabama at Birmingham
Recruiting

Thu, 20 Feb 2020 12:00:00 EST

Randomized, Double-blind, Placebo, Controlled Cross Over Design Topical Morphine for Analgesia in Pediatric Procedures

Condition:   Pain
Interventions:   Drug: Topic Morphine;   Drug: Placebo
Sponsor:   Hospital General de Niños Pedro de Elizalde
Withdrawn

Mon, 24 Nov 2014 12:00:00 EST

Serum Serotonin and Pruritus After Intrathecal Morphine in Cesarean Section

Condition:   Pruritus
Interventions:   Drug: Morphine 100 μg;   Drug: Morphine 200 μg
Sponsor:   Assiut University
Completed

Thu, 06 Jul 2017 12:00:00 EDT

Methadone Versus Morphine for Cancer-Related Pain

Conditions:   Neoplasms;   Pain
Interventions:   Drug: Methadone;   Drug: Morphine
Sponsor:   Mayo Clinic
Terminated

Fri, 14 Dec 2007 12:00:00 EST

The Median Effective Dose (ED50) of Paracetamol and Morphine : A Study of Interaction Study

Condition:   Postoperative Pain
Interventions:   Drug: Paracetamol;   Drug: Morphine;   Drug: Paracetamol- Morphine
Sponsor:   Procare Riaya Hospital
Completed

Mon, 06 Jun 2011 12:00:00 EDT

Safety and Pharmacokinetic Study of Oral Morphine Sulfate in Pediatric Subjects

Condition:   Pain
Intervention:   Drug: Morphine Sulfate
Sponsor:   Roxane Laboratories
Completed

Thu, 24 Mar 2011 12:00:00 EDT

Sleep Apnea and Obesity Affects on Morphine Pharmacokinetics

Conditions:   Pediatric Sleep Apnea;   Obesity;   Morphine Metabolism
Intervention:   Other: Morphine pharmacokinetic evaluation
Sponsor:   Johns Hopkins University
Completed

Mon, 11 Apr 2016 12:00:00 EDT

Oxycodone Versus Intravenous Morphine for Postoperative Analgesia After Hip Surgery

Condition:   Arthroplasty, Replacement, Hip
Interventions:   Drug: Standard Care morphine hydrochloride;   Drug: Oxycodone
Sponsor:   Centre Hospitalier Universitaire de Nīmes
Completed

Wed, 22 Feb 2012 12:00:00 EST

Slow-Release Oral Morphine for the Treatment of Opioid Use Disorder

Conditions:   Opioid-Related Disorders;   Opiate Substitution Treatment;   Morphine;   Methadone;   Fentanyl
Interventions:   Drug: Slow release oral morphine (SROM);   Drug: Methadone
Sponsors:   M. Eugenia Socias;   Canadian Institutes of Health Research (CIHR);   Vancouver Foundation;   Mayne Pharma International Pty Ltd
Suspended

Tue, 14 May 2019 12:00:00 EDT

Low Dose Ketamine (LDK) Versus Morphine for Acute Pain Control in the Emergency Department

Conditions:   Abdomen, Acute;   Other Acute Pain;   Flank Pain;   Back Pain;   Musculoskeletal Pain
Interventions:   Drug: Ketamine;   Drug: Morphine
Sponsors:   Brooke Army Medical Center;   U.S. Air Force Office of the Surgeon General
Completed

Fri, 24 Feb 2012 12:00:00 EST

An Interventional Study for Patient With Cancer Pain to Evaluate the Efficacy and Safety of OxyNorm® Compared to Morphine Sulfate Through the IV Continuous Infusion.

Condition:   Cancer Pain
Interventions:   Drug: Oxycodone Hydrochloride;   Drug: Morphine Sulphate
Sponsor:   Mundipharma Korea Ltd
Completed

Thu, 21 Jan 2016 12:00:00 EST

Impact of Epidural Morphine on Shoulder Pain Following Thoracotomy.

Conditions:   Postoperative Pain;   Shoulder Pain
Interventions:   Drug: Fentanyl;   Drug: Morphine
Sponsor:   Centre hospitalier de l'Université de Montréal (CHUM)
Terminated

Thu, 14 Nov 2013 12:00:00 EST

Enhanced Recovery After Cesarean Section With Low Dose Intrathecal Morphine.

Conditions:   Pain, Postoperative;   Pruritus;   Nausea, Postoperative;   Vomiting, Postoperative
Interventions:   Drug: Morphine Sulfate;   Drug: Bupivacaine Hydrochloride
Sponsor:   Minia University
Recruiting

Thu, 05 Nov 2020 12:00:00 EST

Intrathecal Morphine for Cesarean Delivery

Condition:   Postoperative Pain
Intervention:   Drug: Morphine Sulfate
Sponsor:   Beth Israel Deaconess Medical Center
Not yet recruiting

Wed, 06 Oct 2021 12:00:00 EDT

Low-dose Ketamine vs Morphine for Vaso-occlusive Crisis in Sicklers

Conditions:   Sickle Cell Crisis;   Acute Pain
Interventions:   Drug: Low dose ketamine;   Drug: Morphine
Sponsor:   Makerere University
Completed

Wed, 06 May 2015 12:00:00 EDT

Comparative Study to Evaluate KADIAN and Avinza in Healthy Adults

Condition:   Healthy
Interventions:   Drug: KADIAN (morphine sulfate sustained-release) capsules;   Drug: Avinza (morphine sulfate sustained-release) capsules
Sponsor:   Actavis Inc.
Completed

Fri, 31 Oct 2008 12:00:00 EDT

Effect of Mu-opioid Receptor Genetics on 3 Doses of Spinal Morphine for Postoperative Analgesia After Cesarean Section

Condition:   Postoperative Pain
Intervention:   Drug: Morphine
Sponsor:   Columbia University
Completed

Fri, 04 Nov 2011 12:00:00 EDT

Effect of Tramadol Versus Morphine on PD1 and PD1-ligand in Patients With Chronic Cancer Pain

Condition:   Chronic Pain
Intervention:   Drug: Tramadol Hydrochloride
Sponsor:   Assiut University
Recruiting

Mon, 19 Oct 2020 12:00:00 EDT

Comparison of 0.1 and 0.05mg Intrathecal Morphine for Post-cesarean Analgesia.

Condition:   Cesarean Section
Interventions:   Drug: receiving 0.1 mg IT morphine;   Drug: recieving 0.05 mg IT morphine
Sponsor:   Medical University of South Carolina
Recruiting

Fri, 09 Feb 2018 12:00:00 EST

TAP Block With Intrathecal Fentanyl vs. Intrathecal Morphine in Cesarean Delivery

Condition:   Cesarean Section
Interventions:   Drug: fentanyl;   Drug: morphine;   Procedure: Transversus abdominis plane block;   Procedure: Sham block
Sponsor:   Seoul National University Hospital
Recruiting

Thu, 01 Apr 2021 12:00:00 EDT

Morphine PK Subgroup Analysis

Condition:   Post Operative Pain
Intervention:   Drug: Morphine
Sponsor:   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Completed

Thu, 24 Mar 2011 12:00:00 EDT

Bioequivalence Study of Morphine Sulfate 60 mg Extended-Release Tablets Under Fed Conditions

Condition:   Healthy
Intervention:   Drug: Morphine Sulfate
Sponsor:   Ranbaxy Inc.
Completed

Wed, 15 Aug 2012 12:00:00 EDT

Bioequivalence Study of Morphine Sulfate 60 mg Extended-Release Tablets Under Fasting Conditions

Condition:   Healthy
Intervention:   Drug: Morphine Sulfate
Sponsor:   Ranbaxy Inc.
Completed

Wed, 15 Aug 2012 12:00:00 EDT

Effects of Morphine on Loading-dose Ticagrelor in Patients With ST-segment Elevation Myocardial Infarction

Condition:   ST-segment Elevation Myocardial Infarction
Interventions:   Drug: Morphine;   Drug: metoclopramide;   Drug: saline
Sponsor:   General Hospital of Chinese Armed Police Forces
Recruiting

Fri, 23 Sep 2016 12:00:00 EDT

Comparing Intrathecal Morphine and Intraoperative Lidocaine Infusion to Epidural Anesthesia With Postoperative PCA for Patients Undergoing Exploratory Laparotomy

Conditions:   Cancer Debulking;   Enlarged Uterus;   Fibroid Uterus;   Adnexal Mass
Interventions:   Drug: Bupivacaine;   Drug: Morphine;   Drug: Lidocaine
Sponsors:   Washington University School of Medicine;   The Foundation for Barnes-Jewish Hospital
Not yet recruiting

Mon, 23 Aug 2021 12:00:00 EDT

Bioequivalency Study of Morphine Sulfate Injection, Solution and Tablet Under Fasted Conditions

Condition:   Pain
Intervention:   Drug: morphine sulfate
Sponsor:   Roxane Laboratories
Completed

Wed, 14 Oct 2009 12:00:00 EDT

Ketamine Associated With Morphine PCA After Total Hip Arthroplasty

Condition:   Arthroplasty, Replacement, Hip
Interventions:   Drug: Ketamine-Morphine;   Drug: Morphine;   Drug: Postoperative PCA of Ketamine and morphine
Sponsor:   Assistance Publique - Hôpitaux de Paris
Completed

Tue, 25 Nov 2008 12:00:00 EST

Intrathecal Morphine in Knee Arthroplasty

Conditions:   Pain, Postoperative;   Arthroplasty, Replacement, Knee
Intervention:   Drug: intra thecal morphine
Sponsor:   University College Hospital Galway
Completed

Wed, 11 Jun 2008 12:00:00 EDT

Neurotoxic Adverse Effects of Morphine and Oxycodone for Pain in Terminal Patients With Diminished Renal Function

Conditions:   Pain;   Terminal Illness;   Renal Impairment
Interventions:   Drug: Oxycodone;   Drug: Morphine
Sponsors:   Maastricht University Medical Center;   ZonMw: The Netherlands Organisation for Health Research and Development;   Envida, Maastricht, The Netherlands
Terminated

Mon, 06 Aug 2018 12:00:00 EDT

Intranasal Fentanyl Versus Oral Morphine Sulfate in the Treatment of Pain in Pediatric Trauma

Condition:   Pain, Acute
Interventions:   Drug: Intranasal fentanyl + Oral Placebo;   Drug: Oral Morphine + Intranasal Placebo
Sponsor:   University Hospital, Montpellier
Terminated

Fri, 24 Feb 2017 12:00:00 EST

The Efficacy of Pain Control After Total Hip Replacement Between Ultrasound Guided Supra-inguinal Fascia Iliaca Block and Intrathecal Morphine

Conditions:   Total Hip Replacement;   Ultrasound Guided Supra-inguinal Fascia Iliaca Block;   Intrathecal Morphine;   Postoperative Pain
Interventions:   Drug: Intrathecal morphine;   Drug: Ultrasound guided supra-inguinal fascia iliaca block
Sponsor:   Mahidol University
Recruiting

Thu, 26 Sep 2019 12:00:00 EDT

The Effects of Morphine on Desflurane Consumption and Recovery Time

Condition:   Abdominal Hysterectomy (& Wertheim)
Intervention:   Drug: Morphine
Sponsor:   Baskent University
Completed

Thu, 12 Feb 2015 12:00:00 EST

Comparison of Treatment by IN Ketamine to IV Morphine in Acute Pain

Condition:   Acute Traumatic Pain
Interventions:   Drug: Morphine;   Drug: Ketamine
Sponsors:   Tel-Aviv Sourasky Medical Center;   Medical Corps, Israel Defense Force
Not yet recruiting

Mon, 30 Apr 2018 12:00:00 EDT

Does Local Morphine Add to Local Anesthetics in Serratus Anterior Plane Block Has a System Analgesic Effect?

Condition:   Postoperative Complications
Interventions:   Drug: Morphine Sulfate;   Drug: Bupivacaine Hydrochloride
Sponsor:   Fatma Adel El sherif,MD
Completed

Fri, 11 Nov 2016 12:00:00 EST

Low-dose Spinal Morphine for Post-Thoracotomy Pain After Video-Assisted Thoracoscopic Surgery

Condition:   Video-assisted Thoracoscopic Surgery
Interventions:   Drug: Morphine;   Other: control
Sponsor:   Mahidol University
Completed

Tue, 06 Aug 2013 12:00:00 EDT

Intrathecal Morphine Analgesia vs. Continuous Epidural Analgesia vs. Systemic Analgesia in Colorectal Surgery.

Conditions:   Analgesia, Patient-Controlled;   Epidural Analgesia;   Anesthesia; Spinal;   Morphine;   Surgery, Colorectal;   Intravenous Drug Delivery Systems
Interventions:   Drug: Morphine intrathecal;   Drug: Bupivacaine + Sufentanil epidural;   Drug: Morphine intravenous
Sponsor:   Charles University, Czech Republic
Completed

Mon, 02 Jan 2017 12:00:00 EST

Two Dose Epidural Morphine for Post-cesarean Analgesia

Conditions:   Pain;   Morphine Adverse Reaction
Interventions:   Drug: Epidural Morphine;   Drug: Epidural Saline
Sponsor:   Columbia University
Terminated

Wed, 01 May 2013 12:00:00 EDT

Effectiveness of Controlled-Release Morphine for Chronic Neuropathic Pain After Spinal Cord Injury

Conditions:   Neuropathic Pain;   Spinal Cord Injury
Interventions:   Drug: Modified-release morphine;   Drug: Placebo
Sponsors:   Icahn School of Medicine at Mount Sinai;   U.S. Department of Education
Completed

Wed, 20 Jun 2007 12:00:00 EDT

Morphine Versus Ketorolac in Renal Colic

Condition:   Renal Colic
Interventions:   Drug: Ketorolac;   Drug: Morphine
Sponsor:   Loredana Ghinea
Unknown status

Wed, 25 May 2016 12:00:00 EDT

TAP Catheters Versus Intrathecal Morphine for Cesarean Section

Conditions:   Abdominal Muscles/Ultrasonography;   Adult;   Anesthetics, Local/Administration & Dosage;   Ropivacaine/Administration & Dosage;   Ropivacaine/Analogs & Derivatives;   Cesarean Section;   Humans;   Nerve Block/Methods;   Pain Measurement/Methods;   Pain, Postoperative/Prevention & Control;   Ultrasonography, Interventional
Interventions:   Device: TAP catheter;   Drug: intrathecal morphine
Sponsors:   Stamford Anesthesiology Services, PC;   I-Flow
Unknown status

Tue, 08 May 2012 12:00:00 EDT

Morphine Versus Ketorolac in Low Back Pain

Condition:   Low Back Pain
Interventions:   Drug: Ketorolac;   Drug: Morphine
Sponsor:   Loredana Ghinea
Unknown status

Wed, 25 May 2016 12:00:00 EDT

Randomized, Controlled, Double Blind, to Evaluate the Postpartum Analgesia With Epidural Morphine: Analgesic Effect of Two Different Doses Compared to Placebo

Condition:   Labor Pain
Interventions:   Drug: Morphine;   Drug: saline solution
Sponsor:   Universidad Nacional de Colombia
Completed

Fri, 14 May 2021 12:00:00 EDT

Methadone Associated With Morphine for Cancer Pain

Condition:   Cancer
Interventions:   Drug: Morphine;   Drug: Methadone
Sponsor:   Federal University of São Paulo
Unknown status

Mon, 30 Oct 2017 12:00:00 EDT

Morphine Modulation of The Brain's Pain Matrix

Condition:   Pain
Interventions:   Drug: Morphine;   Other: orange juice
Sponsor:   University of Aarhus
Completed

Mon, 22 Nov 2010 12:00:00 EST

2 Dose Neuraxial Morphine for Prevention of PDPH

Condition:   Postdural Puncture Headache
Interventions:   Drug: Morphine;   Drug: Sterile normal saline
Sponsor:   Columbia University
Recruiting

Tue, 16 Jun 2015 12:00:00 EDT

Evaluation of Oral Morphine Gel in Oral Mucositis Induced by Chemotherapy in Children and Young Adults

Condition:   Cancer
Interventions:   Drug: morphine gel;   Drug: placebo gel
Sponsor:   University Hospital, Strasbourg, France
Unknown status

Wed, 25 Jun 2014 12:00:00 EDT

Efficacy of Topical Morphine in the Treatment of Severe Local Pain of Chronic Wounds

Conditions:   Local Pain;   Chronic Wounds
Interventions:   Drug: Morphine gel;   Other: Neutral gel
Sponsors:   Institut Curie;   Assistance Publique - Hôpitaux de Paris;   Hôpital Louis Mourier
Terminated

Tue, 07 Jan 2014 12:00:00 EST

Comparison of Buprenorphine to Morphine in Treatment of Neonatal Abstinence Syndrome (NAS)

Conditions:   Neonatal Abstinence Syndrome;   Neonatal Withdrawal Syndrome
Interventions:   Drug: Buprenorphine;   Drug: Morphine Sulfate
Sponsor:   Mednax Center for Research, Education, Quality and Safety
Completed

Wed, 17 Oct 2012 12:00:00 EDT

Intraoperative Methadone vs Morphine for Postoperative Pain Control in Patients Undergoing Surgery of the Tibia

Condition:   Pain, Postoperative
Interventions:   Drug: Methadone;   Drug: Morphine
Sponsor:   Baylor College of Medicine
Terminated

Thu, 08 Sep 2011 12:00:00 EDT

Effect of Local Administration of Morphine for Analgesia After Iliac Bone Graft Harvest

Condition:   Autogenous Bone Grafts
Intervention:   Drug: morphine
Sponsors:   The Cleveland Clinic;   Haydarpasa Numune Training and Research Hospital
Withdrawn

Wed, 23 Dec 2009 12:00:00 EST

Validation of an Observational Scale of Dyspnea in Non-communicating Patients in the ICU

Condition:   Dyspnea
Intervention:   Drug: Morphine
Sponsor:   Association pour le Développement et l'Organisation de la Recherche en Pneumologie et sur le Sommeil
Completed

Thu, 16 Jun 2016 12:00:00 EDT

Ketamine Versus Morphine Change Pain Profile

Condition:   Acute Pain
Interventions:   Drug: Ketamine;   Drug: Morphine
Sponsor:   Cairo University
Completed

Mon, 10 Sep 2018 12:00:00 EDT

Post Operative Pain Control: Morphine vs Fentanyl

Condition:   Post Operative Analgesia
Interventions:   Drug: Morphine;   Drug: Fentanyl
Sponsor:   Catholic University of the Sacred Heart
Completed

Mon, 26 May 2014 12:00:00 EDT

Morphine or Fentanyl for Refractory Dyspnea in COPD

Condition:   COPD
Interventions:   Drug: Fentanyl;   Drug: Morphine Retard;   Drug: Placebo patch;   Drug: Placebo oral capsule
Sponsors:   Huib A.M. Kerstjens;   Dutch Foundation for Asthma Prevention;   Innovatiefonds Zorgverzekeraars
Recruiting

Thu, 07 Feb 2019 12:00:00 EST

Study to Assess Pharmacokinetic (PK), Bioavailability & Food Effect of MR902 Compared With Immediate Release (IR) Morphine Sulphate Oral Solution

Condition:   Opioid Substitution Treatment
Interventions:   Drug: MR902;   Drug: IR morphine sulphate
Sponsor:   Mundipharma Research Limited
Completed

Mon, 16 May 2016 12:00:00 EDT

Pre-hospital Morphine Titration : Comparison of 0,05 Versus 0,1 mg/kg

Condition:   Severe, Acute Pain in a Pre-hospital Setting
Intervention:   Drug: morphine
Sponsor:   University Hospital, Toulouse
Completed

Wed, 12 Oct 2005 12:00:00 EDT

Comparison Between Pericapsular Nerve Group Block (PENG) and Morphine Infusion

Conditions:   Analgesia;   Femur Fracture
Interventions:   Procedure: Pericapsular nerve group block;   Drug: Morphine Sulfate
Sponsor:   Suez Canal University
Enrolling by invitation

Thu, 26 Aug 2021 12:00:00 EDT

Morphine, Dyspnea, Exercise and COPD

Condition:   Chronic Obstructive Pulmonary Disease
Interventions:   Drug: Morphine;   Drug: Placebo
Sponsor:   McGill University Health Centre/Research Institute of the McGill University Health Centre
Unknown status

Wed, 31 Oct 2012 12:00:00 EDT

The Effect of Pain Medication in Children With Acute Abdominal Pain and Its Implication Over the Surgeon's Decision

Condition:   Abdominal Pain
Intervention:   Drug: Morphine Sulfate
Sponsor:   University of Texas Southwestern Medical Center
Withdrawn

Tue, 10 Feb 2009 12:00:00 EST

Study of Embeda (Kadian NT, ALO-01) in Subjects With Chronic Moderate to Severe Nonmalignant Pain

Condition:   Pain
Intervention:   Drug: ALO-01 (Morphine Sulfate Plus Naltrexone Hydrochloride ER)
Sponsor:   Pfizer
Completed

Mon, 25 Dec 2006 12:00:00 EST

Analgesics in the Pre-hospital Setting: Implications on Hemorrhage Tolerance - Morphine

Condition:   Healthy
Interventions:   Drug: Morphine;   Other: Placebo
Sponsor:   University of Texas Southwestern Medical Center
Recruiting

Thu, 24 Oct 2019 12:00:00 EDT

Patient Re-education vs. Background Morphine to IV-PCA in Patient With Unsatisfactory Analgesia Post Laparotomy

Condition:   Post-operative Pain
Interventions:   Drug: morphine;   Behavioral: Patient re-education
Sponsor:   Clinical Research Centre, Malaysia
Unknown status

Fri, 14 Aug 2015 12:00:00 EDT

Low Dose Ketamine Versus Morphine for Moderate to Severe Pain in the Emergency Department

Condition:   Pain
Interventions:   Drug: Morphine;   Drug: Ketamine
Sponsor:   Antonios Likourezos
Completed

Thu, 18 Apr 2013 12:00:00 EDT

Pharmacokinetics of Morphine and Oxycodone in Frail Elderly Undergoing Cardiac Surgery

Conditions:   Opioid Use;   Side Effect of Drug;   Postoperative Pain
Intervention:   Drug: Morphine & Oxycodone
Sponsors:   St. Antonius Hospital;   Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Recruiting

Wed, 06 Jan 2021 12:00:00 EST

Oral Pregabalin Effect to the Intravenous Morphine in Multiple Fracture Ribs

Condition:   Fracture; Rib, Multiple
Interventions:   Drug: Pregabalin 150mg;   Drug: Morphine
Sponsor:   Assiut University
Unknown status

Thu, 22 Mar 2018 12:00:00 EDT

Intrathecal Hydromorphone for Pain Control After Cesarean Section

Conditions:   Pain;   Cesarean Section
Interventions:   Drug: Intrathecal morphine;   Drug: Intrathecal hydromorphone
Sponsor:   Icahn School of Medicine at Mount Sinai
Completed

Wed, 26 Mar 2014 12:00:00 EDT

Influence of Naloxone on Ticagrelor Pharmacokinetics and Pharmacodynamics in Patients With Unstable Angina Pectoris on Concomitant Treatment With Morphine

Condition:   Unstable Angina Pectoris
Interventions:   Drug: Crushed ticagrelor followed by morphine;   Drug: Crushed ticagrelor, morphine,naloxone
Sponsor:   Collegium Medicum w Bydgoszczy
Completed

Wed, 19 Oct 2016 12:00:00 EDT

Influence of Metoclopramide on Ticagrelor Pharmacokinetics and Pharmacodynamics in Patients With Unstable Angina Pectoris on Concomitant Treatment With Morphine

Condition:   Unstable Angina Pectoris
Interventions:   Drug: Crushed ticagrelor followed by morphine;   Drug: Crushed ticagrelor, morphine,metoclopramide
Sponsor:   Collegium Medicum w Bydgoszczy
Completed

Wed, 19 Oct 2016 12:00:00 EDT

MST for Parkinson's Disease

Conditions:   Parkinson Disease;   Depression;   Movement Disorders;   Major Depressive Disorder
Intervention:   Device: Magnetic Seizure Theapy (MagPro XP MST)
Sponsor:   University of British Columbia
Recruiting

Fri, 05 Mar 2021 12:00:00 EST

Effect of Granisetron on Morphine Induced Pruritus in Cesarean Section

Condition:   Pruritus
Interventions:   Drug: Morphine Sulfate;   Drug: Placebo;   Drug: Granisetron
Sponsor:   Assiut University
Completed

Fri, 30 Mar 2018 12:00:00 EDT

Effect of Intrathecal Morphine on Chronic Pain After Elective Caesarean Section

Condition:   Chronic Pain Post-Procedural
Interventions:   Drug: Morphine;   Drug: Placebo
Sponsor:   B.P. Koirala Institute of Health Sciences
Completed

Fri, 02 Mar 2018 12:00:00 EST

Comparison of MEOPA + Paracetamol Versus Morphine Treatment in Acute Coronary Syndrome Analgesia.

Condition:   Acute Coronary Syndrome
Interventions:   Drug: MEOPA and paracetamol;   Drug: Morphine
Sponsor:   University Hospital, Toulouse
Completed

Wed, 23 Jul 2014 12:00:00 EDT

CORAL - Cebranopadol Versus Morphine Prolonged-release in Patients With Chronic Moderate to Severe Pain Related to Cancer

Conditions:   Pain;   Neoplasms;   Chronic Pain
Interventions:   Drug: Cebranopadol;   Drug: Morphine Prolonged Release
Sponsor:   Tris Pharma, Inc.
Terminated

Thu, 17 Oct 2013 12:00:00 EDT

Combined Intrathecal Morphine and Dexmedetomidine Analgesia

Condition:   Postoperative Pain
Interventions:   Drug: Dexmedetomidine (Precedex);   Drug: Bupivacaine;   Drug: Morphine
Sponsor:   Assiut University
Completed

Wed, 06 May 2015 12:00:00 EDT

A Study to Compare Safety and Efficacy of Osmotic Release Oral Syytem (OROS) Hydromorphone Hydrochloride (HCl) With Morphine Sustain Release (SR) in Participants With Cancer Pain

Condition:   Cancer Pain
Interventions:   Drug: Hydromprphone Hydrochloride (HCl) OROS;   Drug: Morphine Sustain Release (SR)
Sponsor:   Johnson & Johnson Taiwan Ltd
Terminated

Fri, 05 Dec 2008 12:00:00 EST

Intrathecal Morphine Compared to Conventional Medical Management for Pain Control and Opioid-related Side Effects

Condition:   Chronic Pain
Interventions:   Device: SynchroMed Infusion System and Intrathecal Morphine Sulfate;   Other: Conventional Medicine
Sponsor:   MedtronicNeuro
Terminated

Fri, 16 Aug 2013 12:00:00 EDT

Visceral Pain From the Upper Urinary Tract - a Trial on the Effect of Morphine and Oxycodone in Patients Undergoing PCNL

Condition:   Kidney Stones
Interventions:   Drug: oxycodone;   Drug: morphine
Sponsors:   Katja venborg Pedersen;   Aalborg University Hospital
Completed

Tue, 04 Nov 2008 12:00:00 EST

Morphine to Maximize the Benefits of Exercise Training in COPD or ILD and Persistent Breathlessness

Conditions:   Chronic Obstructive Pulmonary Disease;   Interstitial Lung Disease
Interventions:   Drug: Exercise training with morphine;   Other: Exercise training with placebo
Sponsor:   Dennis Jensen, Ph.D.
Unknown status

Thu, 31 Jan 2019 12:00:00 EST

Intra-Articular Morphine Versus Bupivacaine on Knee Motion in Patients With Osteoarthritis

Condition:   Analgesia
Intervention:   Drug: morphine
Sponsor:   Federal University of São Paulo
Completed

Fri, 14 Mar 2008 12:00:00 EDT

Orthostatic Intolerance and Hypotension After Administration of Morphine in Patients Prior to Hip or Knee Arthroplasty

Conditions:   Orthostatic Hypotension;   Orthostatic Intolerance
Intervention:   Drug: Morphine
Sponsors:   Copenhagen University Hospital, Hvidovre;   Henrik Kehlet
Recruiting

Wed, 26 May 2021 12:00:00 EDT

Sustained-release Morphine Pharmacokinetics in Roux-en-Y Gastric Bypass Subjects

Condition:   Bypass Complications
Intervention:   Drug: Sustained release morphine sulfate, 30 mg
Sponsor:   Hopital Lariboisière
Unknown status

Tue, 29 Dec 2015 12:00:00 EST

Postoperative Pain Relief Following Total Hip Arthroplasty. A Comparison Between Intrathecal Morphine (IM) and Local Infiltration Analgesia (LIA)

Condition:   Primary Osteoarthritis Requiring Total Hip Replacement
Interventions:   Drug: LIA;   Drug: I/T morphine
Sponsor:   Region Örebro County
Unknown status

Mon, 24 Jan 2011 12:00:00 EST

Low Pain Prediction in Cesarean Section Patients

Conditions:   Scheduled Cesarean Sections;   Postoperative Pain Management;   Side Effects
Interventions:   Drug: duramorph;   Drug: placebo
Sponsor:   Wake Forest University Health Sciences
Terminated

Tue, 20 May 2014 12:00:00 EDT

Acupuncture Versus Titrated Morphine in Patients With Renal Colic

Condition:   Renal Colic
Interventions:   Procedure: Traditional Acupuncture Session;   Drug: Morphine Titration
Sponsor:   University of Monastir
Completed

Tue, 24 May 2016 12:00:00 EDT

Safety and Efficacy of Intrathecal Morphine in Children

Condition:   Abdominal Cancer
Intervention:   Procedure: intrathecal morphine
Sponsor:   Alaa Ali Mohamed Elzohry
Completed

Wed, 19 Apr 2017 12:00:00 EDT

Self Medication With Oral Morphine After Total Knee Arthroplasty.

Conditions:   Arthroplasty, Knee Replacement;   Pain Control
Interventions:   Behavioral: Nurse dispensed oral morphine.;   Behavioral: Patient self medication of oral morphine.
Sponsors:   The Royal Bournemouth Hospital;   Royal Bournemouth and Christchurch Hospitals NHS Foundation Trust
Completed

Fri, 22 Oct 2010 12:00:00 EDT

ANalgesic Efficacy and Safety of MOrphiNe Versus Methoxyflurane in Patients With Acute Myocardial Infarction

Conditions:   ST Elevation Myocardial Infarction;   Non ST Segment Elevation Acute Coronary Syndrome
Interventions:   Drug: Methoxyflurane - Penthrox;   Drug: Morphine
Sponsor:   Collegium Medicum w Bydgoszczy
Recruiting

Fri, 17 Jul 2020 12:00:00 EDT

Ultrasound Guided ESP Block Versus Intrathecal Morphine for Postoperative Analgesia in Major HPB Surgery.

Condition:   Postoperative Pain
Interventions:   Procedure: Erector Spinae Plane Block;   Procedure: Intrathecal morphine
Sponsor:   Assiut University
Not yet recruiting

Thu, 19 Nov 2020 12:00:00 EST

Efficacy of Paracetamol in Addition to Morphine to Improve Analgesia in the Emergency Department

Condition:   Analgesia
Interventions:   Drug: Paracetamol;   Drug: Placebo;   Drug: Morphine
Sponsor:   Bruno Minotti
Completed

Mon, 18 Feb 2019 12:00:00 EST

Analgesia Comparison of Nalbuphine and Morphine for Laparoscopic Myomectomy

Condition:   Postoperative Pain
Interventions:   Drug: Nalbuphine;   Drug: Morphine
Sponsor:   Peking University First Hospital
Unknown status

Wed, 20 Sep 2017 12:00:00 EDT

Comparison of Side Effects of Morphine and Hydromorphone Patient-Controlled Analgesia (PCA)

Condition:   Post Operative Pain
Interventions:   Drug: Morphine PCA;   Drug: Hydromorphone PCA
Sponsor:   Columbia University
Completed

Mon, 09 Oct 2006 12:00:00 EDT

Intrathecal Morphine for Unilateral Total Knee Arthroplasty

Condition:   Primary Osteoarthritis of Knee Nos
Interventions:   Procedure: 50 ug IT morphine;   Procedure: 100 ug IT morphine;   Procedure: No IT morphine;   Drug: Morphine;   Drug: Bupivacaine
Sponsor:   Mahidol University
Completed

Fri, 28 Jul 2017 12:00:00 EDT

Comparison Between Methadone and Morphine for Neonatal Opiate Withdrawal

Condition:   Neonatal Abstinence Syndrome
Interventions:   Drug: Methadone;   Drug: Morphine
Sponsor:   Eastern Maine Medical Center
Completed

Tue, 05 Mar 2013 12:00:00 EST

A Efficacy and Safety Trial of Controlled Release (CR) Morphine in Cancer Patients

Conditions:   Pain;   Cancer
Intervention:   Drug: Morphine Sulphate
Sponsor:   Egalet Ltd
Completed

Mon, 12 Mar 2007 12:00:00 EDT

Comparison of Intrathecal and Intravenous Analgesia in Patients Undergoing Liver Resection

Conditions:   Liver Diseases;   Liver Cancer;   Liver Metastases
Interventions:   Procedure: Intravenous morphine;   Procedure: Intrathecal morphine
Sponsor:   Medical University of Warsaw
Unknown status

Wed, 08 Aug 2018 12:00:00 EDT

Intrathecal Morphine for Postoperative Analgesia Following Laparoscopic Bariatric Surgery

Condition:   Postoperative Pain
Interventions:   Drug: intrathecal morphine;   Drug: intrathecal saline
Sponsor:   Assiut University
Unknown status

Thu, 07 Apr 2016 12:00:00 EDT

Morphine as First Drug for Cancer Pain

Condition:   Chronic Pain
Intervention:   Drug: Opioid
Sponsor:   Federal University of São Paulo
Completed

Wed, 29 Feb 2012 12:00:00 EST

Intravenous Buprenorphine Versus Morphine for Severe Pain in the Emergency Department

Condition:   Pain
Interventions:   Drug: Buprenorphine;   Drug: Morphine Sulfate
Sponsor:   Alameda Health System
Unknown status

Tue, 22 Aug 2017 12:00:00 EDT

Influence of Morphine on Pharmacokinetics and Pharmacodynamics of Ticagrelor in Patients With Acute Myocardial Infarction

Conditions:   ST-segment Elevation Myocardial Infarction;   Non-ST-segment Elevation Myocardial Infarction;   VA Drug Interactions
Interventions:   Drug: Morphine;   Drug: Placebo;   Drug: Ticagrelor
Sponsor:   Collegium Medicum w Bydgoszczy
Completed

Fri, 15 Aug 2014 12:00:00 EDT

Incidence of Headache Following an Unintentional Dural Puncture

Conditions:   Postdural Puncture Headache;   Post-Lumbar Puncture Headache;   Cerebrospinal Fluid Leaks
Interventions:   Drug: Morphine;   Drug: Saline
Sponsor:   Northwestern University
Completed

Thu, 07 Nov 2013 12:00:00 EST

Effect of Combined Morphine and Duloxetine on Chronic Pain

Conditions:   Chronic Low Back Pain;   Chronic Neck Pain
Interventions:   Drug: Morphine;   Drug: Duloxetine;   Drug: Placebo
Sponsor:   Massachusetts General Hospital
Recruiting

Tue, 15 Aug 2017 12:00:00 EDT

The Optimal Dosage of Intrathecal Morphine for Peripartum Analgesia

Condition:   Labor Pain
Interventions:   Drug: Morphine;   Drug: Saline
Sponsor:   Beth Israel Deaconess Medical Center
Terminated

Thu, 17 Jun 2010 12:00:00 EDT

Efficacy of Dexmedetomidine Versus Morphine as an Adjunct to Bupivacaine in Caudal Anesthesia.

Condition:   Anesthesia, Local
Interventions:   Drug: Dexmedetomidine;   Drug: Morphine
Sponsor:   Cairo University
Completed

Wed, 24 Jun 2020 12:00:00 EDT

Acupuncture Versus IV Morphine in the Treatment of Acute Pain in ED

Condition:   Renal Colic
Interventions:   Device: acupuncture;   Drug: Morphine
Sponsors:   University of Monastir;   Emergency NGO Onlus
Completed

Mon, 02 Jun 2014 12:00:00 EDT

An Efficacy and Safety Study to Compare Morphine 6-glucuronide (M6G) and Morphine in Patients Suffering With Post-Operative Pain for at Least 24 Hours

Condition:   Postoperative Pain
Interventions:   Drug: Morphine 6-glucuronide;   Drug: Morphine
Sponsors:   Paion UK Ltd.;   Chiltern International Ltd.;   HFL Ltd.
Completed

Mon, 08 Mar 2010 12:00:00 EST

a Small Dose of Naloxone,Minimize Intrathecal Morphine Side Effects

Condition:   Post-Op Complication
Interventions:   Drug: Morphine;   Drug: Morphine-Naloxone
Sponsor:   Assiut University
Completed

Wed, 26 Jul 2017 12:00:00 EDT

Comparison of Surgical Rectus Sheath Block and Intrathecal Morphine

Condition:   Pain
Interventions:   Drug: Bupivacaine;   Drug: Morphine
Sponsor:   Queen Mary Hospital, Hong Kong
Completed

Fri, 03 Jun 2016 12:00:00 EDT

Single Dose Morphine and Fentanyl Added to Intrathecal Mixture on Orthopedics Patients With Undiagnosed Obstructive Sleep Apnea

Condition:   Obstructive Sleep Apnea of Adult
Interventions:   Drug: Morphine;   Drug: Fentanyl
Sponsor:   University of Malaya
Unknown status

Wed, 18 Dec 2013 12:00:00 EST

Pharmacokinetic, Pharmacodynamic and Pharmacogenetic of Morphine After Surgery

Condition:   Orthopaedic Surgery
Intervention:   Drug: intravenous morphine titration
Sponsor:   Assistance Publique - Hôpitaux de Paris
Completed

Wed, 14 Jan 2009 12:00:00 EST

Conversion to Embeda With Rescue Trial

Conditions:   Chronic Disease;   Pain
Intervention:   Drug: morphine sulfate and naltrexone hydrochloride (EMBEDA)
Sponsor:   Pfizer
Terminated

Wed, 11 Aug 2010 12:00:00 EDT

Continuous Pre-uterine Wound Infiltration Versus Intrathecal Morphine for Postoperative Analgesia After Cesarean Section

Condition:   Postoperative Pain
Interventions:   Drug: Ropivacaine;   Drug: Morphine
Sponsors:   Central Hospital, Nancy, France;   Maternite Regionale Universitaire
Unknown status

Fri, 31 Oct 2014 12:00:00 EDT

Morphine Added to Ropivacaine for FICB for Postoperative Analgesia

Condition:   Postoperative Pain
Interventions:   Drug: Ropivacaine, Morphine;   Drug: Ropivacaine, Saline
Sponsor:   B.P. Koirala Institute of Health Sciences
Completed

Thu, 14 Mar 2019 12:00:00 EDT

IV Acetaminophen vs IV Morphine for Pain Control in Pregnant Women

Condition:   Pain Management in Pregnant Women
Interventions:   Drug: IV Acetaminophen;   Drug: IV Morphine
Sponsor:   The University of Texas Health Science Center, Houston
Terminated

Fri, 17 Oct 2014 12:00:00 EDT

Ultrasound Guided TAP Block for Postoperative Analgesia After Abdominal Surgery.

Condition:   Postoperative Pain
Interventions:   Drug: Bupivacaine 0.25% 20ml on each side Sonar guided TAB;   Drug: Morphine 10mg;   Drug: Morphine 15mg
Sponsor:   Assiut University
Completed

Tue, 29 Nov 2016 12:00:00 EST

MIdazolam Versus MOrphine in Acute Pulmonary Edema (MIMO Trial)

Condition:   Acute Pulmonary Edema
Interventions:   Drug: Midazolam;   Drug: Morphine
Sponsor:   Alberto Dominguez-Rodriguez
Unknown status

Fri, 05 Aug 2016 12:00:00 EDT

Spinal Hydromorphone Versus Morphine for Post-Cesarean Delivery Analgesia

Condition:   Postoperative Pain
Interventions:   Drug: Spinal Hydromorphone;   Drug: Spinal Morphine
Sponsor:   Lawson Health Research Institute
Recruiting

Thu, 19 Jul 2018 12:00:00 EDT

Safety and Efficacy Study of Hydromorphone and Morphine

Condition:   Pain
Interventions:   Drug: Morphine;   Drug: Hydromorphone
Sponsor:   Montefiore Medical Center
Completed

Tue, 20 Sep 2005 12:00:00 EDT

Post-operative Oral Morphine Versus Ibuprofen

Condition:   Post-operative Pain
Interventions:   Drug: oral morphine;   Drug: Ibuprofen
Sponsor:   Lawson Health Research Institute
Completed

Tue, 18 Sep 2012 12:00:00 EDT

Comparison Between Dexamethasone and Morphine as an Adjuvant to Bupivacaine for Post-operative Analgesia

Condition:   Lower Extremities Fracture
Interventions:   Drug: Dexamethasone 8 mg;   Drug: Morphine 2 mg
Sponsor:   Indonesia University
Completed

Mon, 13 Feb 2017 12:00:00 EST

Intrathecal Morphine on Transcranial Electric Motor-Evoked Potentials

Condition:   Trauma, Nervous System
Intervention:   Drug: Intrathecal Morphine
Sponsor:   Children's Hospital of Philadelphia
Completed

Thu, 17 Jan 2008 12:00:00 EST

A Study to Assess the Safety, Tolerability and Pharmacokinetics of Multiple Doses of ASP8062 With a Single Dose of Morphine in Recreational Opioid Using Participants

Condition:   Opioid Use Disorder
Interventions:   Drug: ASP8082;   Drug: morphine;   Drug: Placebo
Sponsors:   Astellas Pharma Global Development, Inc.;   National Institute on Drug Abuse (NIDA)
Completed

Fri, 26 Jun 2020 12:00:00 EDT

TC02 Obese Women Using It Morphine vs PCA IV Hydromorphone for Post-Cesarean Analgesia

Conditions:   Pain, Postoperative;   Obesity;   Respiratory Insufficiency
Interventions:   Drug: Intrathecal Morphine;   Drug: Intravenous hydromorphone
Sponsor:   Northwestern University
Withdrawn

Thu, 14 Sep 2017 12:00:00 EDT

Efficacy of Morphine in Reducing the Rate of Early Non-Invasive Ventilation Failure in Acute Exacerbation of Chronic Obstructive Pulmonary Disease, Phase I/IIa

Condition:   Chronic Obstructive Pulmonary Disease
Intervention:   Drug: Morphine hydrochloride
Sponsor:   University Hospital, Grenoble
Recruiting

Thu, 11 Jun 2020 12:00:00 EDT

Respiratory Depression in Women With BMI≥30 Underwent Spinal Anesthesia With Intrathecal Morphine in Elective C-section

Condition:   Respiratory Depression
Interventions:   Device: SOMNOTOUCH RESP;   Procedure: Caesarean section;   Drug: Spinal anesthesia with intrathecal morphine
Sponsor:   Rambam Health Care Campus
Unknown status

Thu, 30 Jun 2016 12:00:00 EDT

Problems With Morphine Use in Patients With a Severe Brain Injury

Conditions:   Head Trauma;   Subarachnoid Hemorrhage;   Close Head Injury
Intervention:   Drug: morphine
Sponsors:   Dalhousie University;   Canadian Institutes of Health Research (CIHR)
Unknown status

Tue, 20 Sep 2005 12:00:00 EDT

The Clinical Evaluation of Implantable Pump System For Safety And Delivery Accuracy In Patients Requiring Intrathecal Administration Of Morphine Sulfate For Chronic Pain

Conditions:   Cancers;   Chronic Pain
Intervention:   Device: Implantation of Morphine Sulfate delivering programmable pump
Sponsor:   Medallion Therapeutics, Inc.
Completed

Fri, 20 Aug 2010 12:00:00 EDT

Epidural Morphine for Postoperative Analgesia After Total Knee Arthroplasty

Conditions:   Adult Patients;   Total Knee Arthroplasty;   Epidural Analgesia;   Femoral Nerve Block;   Analgesic Adverse Reaction
Interventions:   Procedure: Epidural morphine;   Procedure: Epidural placebo;   Procedure: Single femoral nerve block;   Drug: Intravenous morphine analgesia
Sponsor:   Peking University First Hospital
Completed

Thu, 29 Jun 2017 12:00:00 EDT

Transversus Abdominis Plane Block Versus Spinal Morphine After Caesarean Section : A Comparison Study

Condition:   Pregnancy, Ceasarian Section, Anaesthesia
Intervention:   Drug: Intrathecal morphine
Sponsor:   Mbarara University of Science and Technology
Completed

Mon, 28 Aug 2017 12:00:00 EDT

Study to Determine the Bioavailability, Pharmacodynamic Effects, and Safety of Whole and Crushed ALO-01 Compared to Morphine Sulfate Immediate Release (MSIR)

Condition:   Healthy
Interventions:   Drug: ALO-01;   Drug: MSIR;   Drug: Placebo
Sponsor:   Pfizer
Completed

Fri, 12 Sep 2008 12:00:00 EDT

Integrated Pulmonary Index and Opioid Based Patient Controlled Analgesia

Condition:   Brain Tumors
Interventions:   Drug: Morphine PCA 1 mg;   Drug: Morphine PCA 0,5 mg;   Drug: Placebo
Sponsor:   Istanbul University
Completed

Wed, 18 Mar 2020 12:00:00 EDT

Baseline Epidemiologic Assessment of Abuse-Deterrence of MorphaBond Extended Release (BEAD-MB)

Condition:   Baseline Epidemiologic Assessment
Interventions:   Drug: MorphaBond ER;   Drug: Comparator Drug
Sponsor:   Daiichi Sankyo, Inc.
Completed

Thu, 25 Jul 2019 12:00:00 EDT

Oral Morphine Versus Ibuprofen

Conditions:   Upper Extremity Fractures;   Analgesia Post Fracture
Interventions:   Drug: Oral morphine;   Drug: Ibuprofen
Sponsor:   Naveen Poonai
Completed

Mon, 24 Sep 2012 12:00:00 EDT

Post-cesarean Analgesia With Epidural Morphine Following Epidural 2-chloroprocaine

Conditions:   Physiological Effect of Drugs;   Morphine;   Analgesics;   Analgesics, Opioid;   Central Nervous System Depressants;   Narcotics
Interventions:   Drug: 2% lidocaine with 1:200,000 epinephrine and epidural morphine;   Drug: 3% 2-chloroprocaine and epidural morphine
Sponsor:   The University of Texas Health Science Center, Houston
Completed

Thu, 30 Apr 2020 12:00:00 EDT

The Use of Intrathecal Morphine in the Management of Acute Pain Following Decompressive Lumbar Spinal Surgery

Condition:   Acute Pain Following Decompressive Lumbar Spinal Surgery
Interventions:   Drug: Intrathecal Morphine;   Drug: Intrathecal Saline
Sponsor:   University of Calgary
Completed

Thu, 21 Jan 2010 12:00:00 EST

Efficacy of Fentanyl to Reduce the Time of Severe Postoperative Pain Relief Compared to Morphine

Condition:   Postoperative Pain
Interventions:   Drug: Fentanyl;   Drug: Morphine
Sponsor:   Universidad de Antioquia
Completed

Fri, 23 May 2014 12:00:00 EDT

Efficacy and Safety Study of Gabapentin as add-on to Morphine in Paediatric Patients Affected by Chronic Pain

Condition:   Chronic Pain
Interventions:   Drug: Gabapentin + Morphine;   Drug: Placebo + Morphine
Sponsors:   Pharmaceutical Research Management srl;   European Commission
Withdrawn

Thu, 07 Sep 2017 12:00:00 EDT

Palliation of Dyspnea With Morphine in Patients With Interstitial Lung Disease

Conditions:   Interstitial Lung Disease;   Dyspnea;   Morphine
Interventions:   Drug: Morphine hydrochloride;   Other: Placebo
Sponsors:   University of Aarhus;   Skanderbog Apotek
Completed

Fri, 04 Dec 2015 12:00:00 EST

Morphine Sulfate/Placebo for the Treatment of PulmonAry Fibrosis Cough

Condition:   Idiopathic Pulmonary Fibrosis
Interventions:   Drug: Morphine Sulfate;   Drug: Placebo oral tablet
Sponsor:   Royal Brompton & Harefield NHS Foundation Trust
Recruiting

Fri, 12 Jun 2020 12:00:00 EDT

Intrathecal Morphine and Fentanyl for Knee Arthroplasty

Condition:   Knee Arthroplasty
Interventions:   Drug: Intrathecal morphine;   Drug: Intrathecal fentanyl
Sponsor:   Keimyung University Dongsan Medical Center
Unknown status

Thu, 07 Dec 2017 12:00:00 EST

Prevention of Hyperalgesia With Epidural Morphine

Condition:   Hyperalgesia
Interventions:   Drug: Morphine;   Drug: Serum physiologic
Sponsor:   Cukurova University
Unknown status

Fri, 21 Jul 2017 12:00:00 EDT

Pharmacokinetics of Oral Morphine and Pharmacogenomics of CYP2D6 and UGT2B7, in an Urban Pediatric Population Presenting for Elective Surgery

Condition:   Pain
Intervention:   Drug: Morphine
Sponsor:   University of British Columbia
Completed

Fri, 19 Feb 2010 12:00:00 EST

Intrathecal Morphine in Robot-assisted Prostatectomy

Condition:   Prostatic Neoplasms
Interventions:   Drug: The intravenous patient-controlled analgesia;   Drug: The intrathecal morphine injection
Sponsor:   Seoul National University Hospital
Completed

Mon, 25 Nov 2013 12:00:00 EST

Blinded Trial of Buprenorphine or Morphine in the Treatment of the Neonatal Abstinence Syndrome

Condition:   Neonatal Abstinence Syndrome
Interventions:   Drug: sublingual buprenorphine;   Drug: oral morphine
Sponsors:   Thomas Jefferson University;   National Institute on Drug Abuse (NIDA)
Completed

Mon, 17 Oct 2011 12:00:00 EDT

Effects of a Surgery-induced Peripheral Inflammatory Response on the Blood Brain Barrier

Condition:   Dissecting Aneurysm of the Thoracic Aorta
Intervention:   Drug: morphine
Sponsors:   Nova Scotia Health Authority;   Dalhousie University
Completed

Wed, 08 Apr 2009 12:00:00 EDT

Thoracic Epidural Analgesia in Flail Chest

Condition:   Flail Chest
Interventions:   Drug: Morphine Sulfate;   Drug: Triamcinolone Acetonide
Sponsor:   Assiut University
Unknown status

Mon, 29 Jan 2018 12:00:00 EST

Intra-articular Morphine and Clonidine Injections for Pain Management in Hip Arthroscopy

Conditions:   Femoracetabular Impingement;   Pain, Postoperative
Interventions:   Drug: Morphine with clonidine;   Other: Normal saline
Sponsor:   Northwestern University
Completed

Thu, 20 Aug 2015 12:00:00 EDT

Neuraxial Preservative Free Morphine for Normal Spontaneous Vaginal Delivery

Conditions:   Postpartum Pain;   Postpartum Depression;   Opioid Consumption
Interventions:   Drug: Preservative Free Morphine;   Drug: Saline
Sponsor:   Icahn School of Medicine at Mount Sinai
Recruiting

Fri, 12 Jul 2019 12:00:00 EDT

Postoperative Hemodynamics Comparison After High Spinal Block With or Without Intrathecal Morphine.

Condition:   Vasoplegia
Interventions:   Drug: Bupivacaine;   Drug: Bupivacaine + Morphine
Sponsor:   Postgraduate Institute of Medical Education and Research
Unknown status

Thu, 07 Jul 2016 12:00:00 EDT

Comparison of the Erector Spinae Plane Block Versus Intrathecal Morphine on Post-Cesarean Delivery Analgesia

Condition:   Cesarean Section Complications
Interventions:   Procedure: Erector Spinae Plane Block;   Drug: Intrathecal morphine
Sponsors:   McGill University Health Centre/Research Institute of the McGill University Health Centre;   Thammasat University
Recruiting

Wed, 05 Feb 2020 12:00:00 EST

Morphine for Treatment of Dyspnea in Patients With COPD

Condition:   Pulmonary Disease, Chronic Obstructive
Interventions:   Drug: sustained release morphine;   Drug: placebo
Sponsors:   Maastricht University Medical Center;   ZonMw: The Netherlands Organisation for Health Research and Development
Completed

Wed, 29 Apr 2015 12:00:00 EDT

An Efficacy and Safety Study to Compare Fentanyl Ionsys and Routine Care With Intravenous (IV) Morphine Patient-controlled Analgesia (PCA) in Participants Who Have Undergone Elective Major Abdominal or Orthopedic Surgery

Condition:   Pain, Postoperative
Interventions:   Device: Fentanyl IONSYS;   Device: Morphine IV PCA
Sponsor:   Janssen-Cilag Ltd.
Terminated

Mon, 06 Oct 2008 12:00:00 EDT

intrathecaم Ketamine, Morphine and Both for Lower Abdominal Cancer Surgery Pain

Condition:   Postoperative Pain
Interventions:   Drug: intrathecal morphine;   Drug: intrathecal ketamine;   Drug: intrathecal morphine + ketamine
Sponsor:   Assiut University
Completed

Mon, 04 Apr 2016 12:00:00 EDT

Effect of Intrathecal Morphine, Dexmedetomidine or Both in Combination to Bupivacaine on Immunity

Condition:   Immune System Suppression
Interventions:   Drug: Morphine Sulfate;   Drug: Dexmedetomidine;   Drug: Bupivacaine
Sponsor:   Assiut University
Active, not recruiting

Thu, 19 Jan 2017 12:00:00 EST

A Randomized Controlled Trial Comparing Intrathecal Morphine With Quadratus Lumborum Block for Post-cesarean Delivery Analgesia

Condition:   Cesarean Section
Interventions:   Other: Bilateral Quadratus lumborum block with 0.5% ropivacaine;   Other: Intrathecal Morphine with 100 mcg morphine
Sponsors:   Vishal Uppal;   IWK Health Centre;   Maisonneuve-Rosemont Hospital
Recruiting

Thu, 18 Aug 2016 12:00:00 EDT

RANDOMISED STUDY OF EPIDURAL VS MPCA MORPHINE VS TAPP IN LAPAROSCOPIC SIGMOIDECTOMY

Condition:   Sigmoidal Tumour
Interventions:   Drug: L-BUPIVACAINE ; MORPHINE;   Drug: MORPHINE
Sponsor:   Corporacion Parc Tauli
Unknown status

Mon, 08 Apr 2013 12:00:00 EDT

Ketamine and Morphine Versus Morphine Alone for the Treatment of Acute Pain in the Emergency Department

Condition:   Acute Pain
Interventions:   Drug: Ketamine;   Drug: Morphine;   Drug: placebo
Sponsors:   University of Arizona;   Arizona College of Emergency Physicians
Unknown status

Wed, 17 Jul 2013 12:00:00 EDT

Morphine vs. Oxycodone for Postoperative Pain Management

Conditions:   Hysterectomy;   Myoma;   Postoperative Pain;   Opioids
Intervention:   Drug: Morphine and oxycodone
Sponsors:   Ullevaal University Hospital;   University of Oslo
Completed

Wed, 12 Sep 2007 12:00:00 EDT

Dosage of Epidural Morphine in Elderly Patients

Conditions:   Age Problem;   Abdominal Cancer
Interventions:   Drug: 1.5 mg of Morphine Sulfate;   Drug: Normal saline;   Drug: 3 mg of Morphine Sulfate;   Drug: 4.5 mg of Morphine Sulfate
Sponsor:   Assiut University
Completed

Fri, 20 Mar 2020 12:00:00 EDT

Analgesic Efficacy of Paravertebral Morphine

Condition:   Acute Pain
Interventions:   Drug: PVB morphine;   Drug: PVB bupivacaine
Sponsor:   Assiut University
Unknown status

Wed, 20 Dec 2017 12:00:00 EST

OxyNorm Capsules in Post-Operative Pain Study

Condition:   Postoperative Pain
Interventions:   Drug: OxyNorm Capsules;   Other: Morphine tablet
Sponsor:   Mundipharma (China) Pharmaceutical Co. Ltd
Completed

Thu, 30 Aug 2012 12:00:00 EDT

Measuring the Amount of Methadone or Morphine in the Blood of Neonates, Infants & Children After Cardiac Surgery.

Condition:   Pain
Interventions:   Drug: Methadone;   Drug: Morphine
Sponsors:   Stanford University;   University of Colorado, Denver;   Oregon Health and Science University
Completed

Mon, 29 Mar 2010 12:00:00 EDT

Low Dose Morphine to Relieve Dyspnea in Acute Respiratory Failure (OPIDYS)

Condition:   Acute Respiratory Failure
Interventions:   Drug: Chlorhydrate de morphine;   Drug: NaCl 0,9%,
Sponsor:   Assistance Publique - Hôpitaux de Paris
Recruiting

Fri, 24 Apr 2020 12:00:00 EDT

Postoperative Effects of Intranasal Fentanyl, IV and IM Morphine in Children Undergoing Myringotomy

Condition:   Otitis Media
Interventions:   Drug: Intranasal fentanyl;   Drug: morphine IM;   Drug: IV morphine
Sponsor:   Baylor College of Medicine
Completed

Fri, 19 Nov 2010 12:00:00 EST

Comparing Clinical Outcomes Between Ketamine-midazolam and Morphine-midazolam for Continous Sedation in ICU Patients.

Condition:   Critical Illness
Interventions:   Combination Product: Ketamine-Midazolam;   Combination Product: Morphine -Midazolam
Sponsors:   Makerere University;   THRiVE
Terminated

Tue, 23 Jan 2018 12:00:00 EST

Erector Spinae Block vs Morphine in Vertebral Fixation

Conditions:   Vertebral Subluxation;   Spine Disease;   Spondylolisthesis
Interventions:   Procedure: Erector Spinae plane Block;   Drug: Patient controlled analgesia with intravenous morphine
Sponsor:   AUSL Romagna Rimini
Recruiting

Thu, 28 Jan 2021 12:00:00 EST

Intrathecal Morphine,Femoral Nerve Block,Periarticular Bupivacaine Infiltration for Pain After Intramedullary Hip Screw

Condition:   Femoral Neck Fractures
Intervention:   Drug: Bupivacaine, morphine
Sponsor:   Mahidol University
Unknown status

Wed, 13 Oct 2010 12:00:00 EDT

Morphine Versus Methadone As First Line Strong Opioid for Cancer Pain

Conditions:   Advanced Cancer;   Solid Tumors
Interventions:   Drug: Morphine;   Drug: Methadone
Sponsors:   M.D. Anderson Cancer Center;   National Cancer Institute (NCI)
Terminated

Wed, 12 Mar 2008 12:00:00 EDT

Efficacy of Transverses Abdominis -Plane Block With Bupivacaine Versus Bupivacaine With Morphine Postoperatively

Condition:   Abdominal Cancer
Intervention:   Drug: transversus abdominis-plane block with local anesthetic 20 ml of bupivacaine 0.5% + 10 mg morphine
Sponsor:   Assiut University
Completed

Fri, 02 Oct 2015 12:00:00 EDT

Optimizing the Use of Morphine in Pre-Term Neonates

Condition:   Premature Neonates
Intervention:   Drug: Morphine
Sponsors:   John van den Anker;   University of Louisville;   Erasmus Medical Center
Completed

Fri, 29 Jun 2007 12:00:00 EDT

Morphine Versus Ketamine as Adjuvants in Paravertebral Blocks

Conditions:   Pain, Postoperative;   Pain, Acute;   Pain, Chronic;   Pain, Neuropathic;   Morphine;   Ketamine;   Analgesia
Interventions:   Drug: local anesthetic-morphine;   Drug: local anesthetic-ketamine;   Drug: local anesthetic
Sponsors:   Aretaieion University Hospital;   KAT General Hospital
Active, not recruiting

Wed, 21 Apr 2021 12:00:00 EDT

Intrathecal Opioids for Pain Control After Cesarean Delivery: Determining the Optimal Dose

Conditions:   Analgesia, Obstetrical;   Cesarean Section
Interventions:   Drug: Morphine;   Drug: Hydromorphone
Sponsor:   Mayo Clinic
Completed

Thu, 12 Dec 2013 12:00:00 EST

Comparison of Transdermal Fentanyl and Morphine for Oral Mucositis Pain in Nasopharyngeal Cancer Patients

Conditions:   Pain;   Nasopharyngeal Carcinoma;   Head and Neck Cancer;   Radiation Induced Oral Mucositis
Interventions:   Drug: Fentanyl;   Drug: Morphine
Sponsor:   Jiarong Chen, MD
Not yet recruiting

Tue, 03 Mar 2020 12:00:00 EST

Safety Study to Assess Opiate Withdrawal Signs and Symptoms in Opioid Dependent Patients

Condition:   Chronic Pain
Interventions:   Drug: EMBEDA™ (morphine sulfate/naltrexone hydrochloride) crush;   Drug: EMBEDA™ (morphine sulfate/naltrexone hydrochloride) whole
Sponsor:   Pfizer
Terminated

Fri, 09 Apr 2010 12:00:00 EDT

Comparing Ketamine and Morphine in the Treatment of Acute Fracture Pain

Conditions:   Acute Pain;   Fractures
Interventions:   Drug: ketamine;   Drug: morphine
Sponsors:   Washington University School of Medicine;   MOCEP
Terminated

Thu, 30 Apr 2015 12:00:00 EDT

A Study of Embeda (Kadian NT, ALO-01) in Subjects With Pain Due to Osteoarthritis of the Hip or Knee

Conditions:   Osteoarthritis;   Chronic Pain
Interventions:   Drug: ALO-01 (Morphine Sulfate Plus Naltrexone Hydrochloride Extended Release);   Drug: Placebo
Sponsor:   Pfizer
Completed

Thu, 11 Jan 2007 12:00:00 EST

Epidural Morphine for Analgesia After Traumatic Vaginal Delivery

Condition:   Traumatic Vaginal Delivery
Interventions:   Drug: Morphine;   Drug: Placebo
Sponsor:   Lawson Health Research Institute
Withdrawn

Fri, 21 Sep 2012 12:00:00 EDT

Nasal Fentanyl for Chronic Cancer Pain

Conditions:   Cancer;   Pain
Interventions:   Drug: intranasal fentanyl spray;   Drug: slow release morphine
Sponsors:   Norwegian University of Science and Technology;   St. Olavs Hospital;   Fondazione IRCCS Istituto Nazionale dei Tumori, Milano;   L'Hospitalet de Llobregat;   University Hospital, Bonn;   Cantonal Hospital of St. Gallen;   Maastricht University Medical Center;   Flinders University
Withdrawn

Tue, 23 Jul 2013 12:00:00 EDT

Ropivacaine Through Continuous Infusion Versus Epidural Morphine for Postoperative Analgesia After Emergency Cesarean Section

Condition:   Postoperative Pain
Interventions:   Drug: Ropivacaine;   Drug: Morphine
Sponsor:   University Hospital, Grenoble
Active, not recruiting

Tue, 07 Apr 2015 12:00:00 EDT

Transversus Abdominis Plane (TAP) Block Versus Intrathecal Morphine for Caesarean Section - Randomised Controlled Trial

Condition:   Postoperative Pain
Interventions:   Other: spinal anesthesia with intrathecal morphine;   Other: TAP-block with ropivacaine and clonidine
Sponsors:   Benno Rehberg-Klug;   Domitille Dereu
Completed

Thu, 29 Aug 2013 12:00:00 EDT

Effect of Timing on Efficacy of Morphine Analgesia After 2-chloroprocaine Anesthesia

Conditions:   Labor;   Analgesia, Epidural
Interventions:   Drug: Morphine-CP-saline (MCS);   Drug: saline-2CP-morphine (SCM);   Drug: saline-lidocaine-morphine (SLM)
Sponsor:   Northwestern University
Completed

Fri, 15 Jun 2007 12:00:00 EDT

Intrathecal Morphine for Inguinal Hernia Repair.

Conditions:   Inguinal Hernia;   Nausea;   Vomiting;   Pruritus;   Postoperative Pain
Interventions:   Drug: intrathecal morphine 0.1 mg combined with intrathecal heavy bupivacaine 7.5 mg;   Drug: intrathecal morphine 0.4 mg combined with intrathecal heavy bupivacaine 7.5 mg;   Device: standard monitoring with Datex Ohmeda anesthesia monitor, GE, Finland;   Drug: intravenous cannulation and premedication
Sponsor:   Ankara University
Completed

Thu, 05 Dec 2013 12:00:00 EST

Use of Morphine Gel Topically in Patients With Stage 2-3 Wounds

Condition:   Wounds
Interventions:   Drug: morphine topical gel;   Drug: placebo
Sponsor:   Banner Health
Unknown status

Fri, 19 Sep 2008 12:00:00 EDT

Epidural Methadone in Healthy Volunteers

Condition:   Pain, Acute
Interventions:   Drug: Methadone hydrochloride;   Drug: Morphine Sulfate
Sponsor:   simon.haroutounian
Completed

Tue, 15 May 2018 12:00:00 EDT

Epidural Low Dose Morphine in Postoperative Pain After Posterior Lumbar Spinal Surgery

Condition:   Morphine
Interventions:   Drug: 1 mg morphine soak in epidural oxidized cellulose;   Drug: normal saline
Sponsor:   Mahidol University
Completed

Thu, 20 Feb 2014 12:00:00 EST

Effects of Analgesics in Cesarean Section Elective

Condition:   Anesthesia; Functional
Interventions:   Drug: Hyperbaric bupivacaine+Sufentanil;   Drug: Hyperbaric bupivacaine+Morphine
Sponsor:   Fundación Pública Andaluza Progreso y Salud
Completed

Fri, 29 Dec 2017 12:00:00 EST

Intravenous Subdissociative-dose Ketamine Versus Morphine for Prehospital Analgesia

Condition:   Pain Management
Interventions:   Drug: Ketamine;   Drug: Morphine
Sponsor:   Nantes University Hospital
Recruiting

Wed, 02 Aug 2017 12:00:00 EDT

Fentanyl Buccal Tablet for the Relief of Episodic Breathlessness in Cancer Patients

Conditions:   Cancer;   Dyspnea, Paroxysmal
Interventions:   Drug: Fentanyl;   Drug: Immediate release morphine
Sponsors:   University of Cologne;   Teva Pharmaceutical Industries
Completed

Thu, 19 Nov 2020 12:00:00 EST

IV Paracetamol vs IV Morphine vs Placebo in Sciatalgia

Condition:   Sciatica
Interventions:   Drug: Paracetamol;   Drug: morphine;   Drug: Placebo
Sponsors:   Akdeniz University;   Pamukkale University;   Antalya Training and Research Hospital;   University of Gaziantep;   Ataturk University
Unknown status

Wed, 22 Jul 2015 12:00:00 EDT

Trial Comparing Morphine to Hydromorphone in Elderly Patients With Severe Pain

Condition:   Acute Pain
Interventions:   Drug: Morphine;   Drug: Hydromorphone
Sponsor:   Montefiore Medical Center
Completed

Tue, 21 Mar 2006 12:00:00 EST

Intrathecal Morphine and Local Infiltration Analgesia in Total Knee Arthroplasty

Condition:   Pain, Postoperative
Interventions:   Drug: Bupivacaine Hydrochloride, Spinal;   Drug: Morphine hydrochloride, Spinal;   Drug: Placebo - Concentrate
Sponsor:   South Carelia Central Hospital
Unknown status

Thu, 15 Feb 2018 12:00:00 EST

The Effect of Morphine on Prasugrel Absorption in STEMI Patients

Condition:   Cardiovascular Disease
Interventions:   Drug: morphine;   Drug: saline
Sponsor:   Sheffield Teaching Hospitals NHS Foundation Trust
Completed

Wed, 22 Feb 2012 12:00:00 EST

Neuroimmune Effects of Opioid Administration

Condition:   Drug Effect
Interventions:   Drug: High Morphine Dose;   Drug: Low Morphine Dose
Sponsor:   Yale University
Completed

Fri, 11 Jan 2019 12:00:00 EST

Safety and Efficacy of the Addition of Morphine Chloride to a Low Dose of Bupivacaine as Intradural Anaesthetic for the Removal Surgery of the Hemorrhoids

Condition:   Surgical Remove of Hemorrhoids
Interventions:   Drug: Bupivacaine low dose;   Drug: Bupivacaine standard dose;   Drug: Morphine Chloride
Sponsors:   Fundacion para la Investigacion Biomedica del Hospital Universitario Principe de Asturias;   Spanish Agency of Medicines and Health Products;   Spanish Health Ministry
Completed

Tue, 28 Jan 2014 12:00:00 EST

Use of Caudal Anesthesia Supplemented With Morphine in Children Undergoing Renal Surgery

Condition:   Anesthesia, Caudal
Interventions:   Drug: caudal anesthesia;   Drug: caudal anesthesia supplemented with morphine
Sponsor:   Shaare Zedek Medical Center
Completed

Wed, 05 Jun 2013 12:00:00 EDT

Wound Infusion vs Spinal Morphine for Post-caesarean Analgesia

Condition:   Post Caesarean Analgesia
Interventions:   Drug: ropivacaine infiltration;   Drug: intrathecal morphine;   Drug: placebo
Sponsor:   Dr Madeleine Wilwerth
Completed

Wed, 15 Oct 2014 12:00:00 EDT

Effetc of Intrathecal Morphine on Vesical Function After Caesarean Section

Condition:   Analgesia
Interventions:   Drug: Morphine;   Drug: NaCl 0.9%;   Drug: 50 mg prilocaine + 2.5 mcg sufentanil
Sponsor:   University of Liege
Not yet recruiting

Mon, 13 Sep 2021 12:00:00 EDT

Comparison of Adverse Drug Reactions Associated for Oxycodone and Morphine in Postoperative Pain After Abdominal Hysterectomy

Condition:   Pain, Postoperative
Interventions:   Drug: Morphine;   Drug: Oxycodone
Sponsor:   Hospital Civil de Guadalajara
Unknown status

Tue, 18 Oct 2016 12:00:00 EDT

First Evaluation of Morphine Hydrochloride by Nebulisation in Healthy Volunteers

Condition:   Acute Pain
Interventions:   Drug: Morphine;   Drug: Fentanyl
Sponsor:   University Hospital, Rouen
Completed

Tue, 05 Nov 2013 12:00:00 EST

Comparison of KADIAN 100 mg When Dosed With Alcohol Under Fasting and Fed Conditions Compared to Water

Condition:   Healthy
Interventions:   Drug: KADIAN Capsule + alcohol (under fasting conditions);   Drug: KADIAN Capsule + water (under fasting conditions);   Drug: morphine sulfate IR oral solution + water;   Drug: KADIAN Capsule + alcohol (under fed conditions)
Sponsor:   Actavis Inc.
Completed

Tue, 07 Oct 2008 12:00:00 EDT

Nalbuphine Versus Morphine for Mucositis Pain in Pediatric Cancer Patients

Conditions:   Acute Myeloid Leukemia;   Stem Cell Leukemia
Interventions:   Drug: Nalbuphine;   Drug: Morphine
Sponsor:   Children's Cancer Hospital Egypt 57357
Completed

Thu, 31 Jan 2019 12:00:00 EST

Double Bedtime Dosing During Immediate-release Morphine Administration to Cancer Patients

Condition:   Cancer
Interventions:   Drug: single dose Morphine;   Drug: double dose Morphine;   Drug: placebo
Sponsor:   Norwegian University of Science and Technology
Completed

Tue, 20 Sep 2005 12:00:00 EDT

The Efficacy of Peripheral Nerve Blocks With Intrathecal Morphine in Improving Analgesia After Unilateral Total Knee Arthroplasty

Conditions:   Anesthesia;   Total Knee Arthroplasty
Interventions:   Drug: Combined spinal epidural anesthesia technique with intrathecal morphine;   Drug: A combination of combined spinal-epidural (with intrathecal morphine) and femoral nerve block;   Drug: A combination of combined spinal-epidural (with intrathecal morphine) and femoral nerve block as well as sciatic nerve block
Sponsor:   American University of Beirut Medical Center
Completed

Fri, 09 May 2014 12:00:00 EDT

Magnetic Seizure Therapy (MST) for Treatment Resistant Depression, Schizophrenia, and Obsessive Compulsive Disorder

Conditions:   Depressive Disorder;   Schizophrenia;   Schizoaffective Disorder;   Obsessive-Compulsive Disorder
Intervention:   Device: Magnetic Seizure Therapy (MagPro MST)
Sponsors:   Centre for Addiction and Mental Health;   University Health Network, Toronto
Completed

Fri, 11 May 2012 12:00:00 EDT

Dexmedetomidine Versus Morphine and Midazolam in Prevention and Treatment of Delirium After Adult Cardiac Surgery

Condition:   Delirium
Interventions:   Drug: Dexmedetomidine Hydrochloride;   Drug: Morphine and Midazolam
Sponsor:   Ain Shams University
Completed

Tue, 14 Mar 2017 12:00:00 EDT

Dose Proportionality and Food Effect of Morphine Sulfate

Condition:   Pain
Intervention:   Drug: morphine sulfate
Sponsor:   Roxane Laboratories
Completed

Wed, 14 Oct 2009 12:00:00 EDT

Low-dose Ketamine for Acute Pain in the Emergency Department

Condition:   Pain
Interventions:   Drug: Ketamine;   Drug: Placebos;   Drug: Morphine
Sponsor:   Faculty of Medicine, Sousse
Unknown status

Wed, 11 Jan 2017 12:00:00 EST

Topical Morphine for Analgesia in Patients With Skin Grafts

Conditions:   Skin Transplantation;   Pain
Interventions:   Other: Placebo;   Drug: Morphine - .25 mg;   Drug: Morphine
Sponsor:   Rambam Health Care Campus
Not yet recruiting

Wed, 09 Aug 2006 12:00:00 EDT

Effect Of Combination of Morphine+Fentanyl on Emergence Delirium in Patients of Cleft Lip and Palate Repair

Condition:   Anesthesia Emergence Delirium
Interventions:   Drug: MORPHINE PLUS FENTANYL;   Drug: Fentanyl
Sponsor:   Postgraduate Institute of Medical Education and Research
Completed

Thu, 05 Jan 2017 12:00:00 EST

Spinal Bupivacaine/Morphine in Laparoscopic Gastro-intestinal Surgery

Condition:   Spinal Bupivacaine/Morphine in Laparoscopic Surgery
Interventions:   Drug: Spinal injection bupivacaine/morphine;   Drug: subcutaneum injection lidocaine
Sponsor:   Maasstad Hospital
Completed

Thu, 06 Nov 2014 12:00:00 EST

Intranasal Sufentanil Versus Intravenous Morphine for the Management of Acute Pain

Condition:   Acute Pain
Interventions:   Drug: Sufentanil;   Drug: Normal saline;   Drug: Morphine
Sponsor:   The Brooklyn Hospital Center
Unknown status

Fri, 21 Jul 2017 12:00:00 EDT

Randomized Double Blind Controlled Trial Comparing a Blind Sciatic Nerve Block in the Popliteal Fossa to Intravenous Morphine for Traumatic Severe Acute Pain in the Prehospital Setting

Conditions:   Injuries;   Pain;   Emergencies
Interventions:   Drug: Mepivacaine;   Drug: Morphine
Sponsor:   Centre Hospitalier Annecy Genevois
Terminated

Tue, 31 Jan 2012 12:00:00 EST

Morphine-Sparing Efficacy Of Parecoxib In Pain Treatment After Radical Prostatectomy

Condition:   Pain, Postoperative
Interventions:   Drug: Morphine, Parecoxib;   Drug: Morphine, Placebo
Sponsor:   Pfizer
Terminated

Thu, 29 Jun 2006 12:00:00 EDT

CAUDAL BUPIVACAINE VERSUS INTRAVENOUS MORPHINE ON TIME TO FIRST ANALGESIC REQUIREMENT

Condition:   Post Operative Pain
Interventions:   Drug: caudal bupivacaine;   Drug: intravenous morphine
Sponsor:   Makerere University
Completed

Thu, 28 May 2015 12:00:00 EDT

Satisfactory Analgesia Minimal Emesis in Day Surgeries

Conditions:   Pain;   Post Operative Nausea and Vomiting
Interventions:   Drug: Morphine;   Drug: Hydromorphone
Sponsor:   McMaster University
Completed

Fri, 22 Aug 2014 12:00:00 EDT

Preemptive Analgesia for Post Tonsillectomy Pain With IV Morphine in Children

Conditions:   Preoperative Sedation;   Postoperative Pain
Interventions:   Drug: Morphine premedication;   Drug: Midazolam premedication;   Drug: Saline premedication (placebo)
Sponsor:   Dr. Soliman Fakeeh Hospital
Unknown status

Fri, 16 Dec 2016 12:00:00 EST

Morphine and/or Nalbuphine as Adjuvants in Ultrasound Guided Interscalene Block: for Shoulder Surgeries

Condition:   Rotator Cuff Tear
Interventions:   Drug: Morphine;   Drug: Nalbuphine;   Drug: Bupivacaine 0.5%;   Drug: Lidocaine Hydrochloride 1% and epinephrine 1:400,000
Sponsor:   Assiut University
Unknown status

Fri, 27 Jan 2017 12:00:00 EST

Abuse Potential of Orally Administered Crushed Embeda Compared to Crushed Controlled-Release Morphine and Placebo in Non-Dependent Recreational Opioid Users

Condition:   Nondependent Opioid Abuse, Episodic
Interventions:   Drug: Placebo;   Drug: MS Contin (morphine sulfate, controlled release);   Drug: EMBEDA (morphine sulfate / naltrexone hydrochloride)
Sponsor:   Pfizer
Completed

Mon, 27 Jun 2011 12:00:00 EDT

Opioid Titration With 12.5 ug/h Fentanyl Transdermal Patch vs Orally Morphine for Opioid-naïve Patients With Moderate Cancer Pain

Condition:   Opioid, Moderate Cancer Pain, Transdermal Fentanyl, 12.5ug/h, Opioid-naive
Interventions:   Drug: 2.5ug/h transdermal fentanyl;   Drug: Oral immediate-released morphine
Sponsor:   Fujian Cancer Hospital
Not yet recruiting

Mon, 31 Aug 2020 12:00:00 EDT

IV NSAI Versus Nebulized Morphine Analgesia for First-line Renal Colic

Condition:   Renal Colic
Interventions:   Drug: IV NSAI;   Drug: NM;   Drug: IV Serum Saline;   Drug: Nebulised Serum Saline
Sponsor:   University of Monastir
Completed

Thu, 05 Jun 2014 12:00:00 EDT

Femoral/Sciatic Block for Knee Surgery

Condition:   Knee Injuries
Interventions:   Procedure: femoral nerve blockade;   Procedure: morphine
Sponsor:   University of Sao Paulo General Hospital
Completed

Mon, 29 Aug 2016 12:00:00 EDT

Patient Satisfaction With Subdissociative Dose Ketamine Versus Morphine for Emergency Department Pain Control

Condition:   Abdominal Pain
Interventions:   Drug: Ketamine;   Drug: Morphine
Sponsor:   CHRISTUS Health
Completed

Thu, 07 Jan 2021 12:00:00 EST

QUALITY OF RECOVERY AFTER INTRAOPERATIVE MORPHINE OR METHADONE

Conditions:   Pain, Postoperative;   Nausea and Vomiting, Postoperative
Interventions:   Drug: Methadone;   Drug: Morphine
Sponsor:   Pontificia Universidade Catolica de Sao Paulo
Completed

Tue, 07 Feb 2017 12:00:00 EST

"Red Morphine Drops" for Symptomatic Treatment of Dyspnoea in Lung Cancer

Conditions:   Dyspnea;   Lung Neoplasms
Interventions:   Drug: Morphine p.o.;   Drug: Morphine s.c.
Sponsor:   Sankt Lukas Hospice
Completed

Tue, 20 Jun 2006 12:00:00 EDT

Combined Epidural Morphine and Midazolam on Postoperative Pain

Condition:   Acute Postoperative Pain
Intervention:   Drug: midazolam
Sponsor:   Assiut University
Recruiting

Fri, 26 Jul 2019 12:00:00 EDT

Influence of Morphine or Ketamine or Saline Applied During In-hospital Cardiopulmonary Resuscitation on Early Survival

Condition:   Cardiac Arrest
Interventions:   Drug: Morphine;   Drug: Ketamine Injectable Solution;   Drug: Saline 0.9%
Sponsor:   University Hospital, Akershus
Not yet recruiting

Fri, 05 Jul 2019 12:00:00 EDT

Impact of Intrathecal Morphine on Sleep Apnea Syndrome

Condition:   Sleep Apnea Syndromes
Interventions:   Drug: Bupivacaine with normal saline;   Drug: Bupivacaine with intrathecal morphine
Sponsor:   Centre Hospitalier Universitaire Vaudois
Completed

Fri, 02 Oct 2015 12:00:00 EDT

Embrace TDD: Post-Market Study to Evaluate Intrathecal Morphine as an Alternative to Systemic Opioids for Chronic Pain

Conditions:   Chronic Non-malignant Pain;   Chronic Pain;   Pain, Back;   Pain, Leg
Interventions:   Device: Medtronic SynchroMed™ II infusion system;   Drug: Preservative-free morphine sulfate (PFMS)
Sponsor:   MedtronicNeuro
Active, not recruiting

Mon, 03 Dec 2018 12:00:00 EST

Prediction of Inter-individual Differences in the Response to Morphine Versus Milnacipran in Patients With Sciatica

Condition:   Neuropathic Pain
Interventions:   Drug: Morphine;   Drug: Milnacipran
Sponsor:   Rambam Health Care Campus
Unknown status

Thu, 01 Aug 2013 12:00:00 EDT

Morphine Versus Methadone for Opiate Exposed Infants With Neonatal Abstinence Syndrome

Condition:   Neonatal Abstinence Syndrome
Interventions:   Drug: Morphine;   Drug: Methadone
Sponsor:   University of New Mexico
Unknown status

Mon, 01 Aug 2016 12:00:00 EDT

Morphine for Dyspnea in Pulmonary Fibrosis

Condition:   Idiopathic Pulmonary Fibrosis (IPF)
Interventions:   Drug: Morphine hydrochloride;   Drug: Placebo
Sponsor:   Medical University of Gdansk
Not yet recruiting

Tue, 04 Aug 2020 12:00:00 EDT

Pramipexole and Morphine for Renal Colic

Condition:   Renal Colic
Interventions:   Drug: Pramipexole;   Drug: Morphine;   Drug: Placebo oral tablet
Sponsor:   East Carolina University
Recruiting

Wed, 13 Nov 2019 12:00:00 EST

A Multicenter, Randomized, Open-Label, Parallel-Group Trial to Compare the Efficacy and Safety of the Sufentanil NanoTab PCA System/15 mcg (Zalviso™)to Intravenous Patient-Controlled Analgesia With Morphine for the Treatment of Acute Post-Operative Pain

Condition:   Post-Operative Pain
Interventions:   Drug: Sufentanil NanoTab PCA System/15 mcg;   Drug: morphine IV PCA
Sponsor:   AcelRx Pharmaceuticals, Inc.
Completed

Mon, 27 Feb 2012 12:00:00 EST

Analgesic Efficacy of (MSIR)/Acetaminophen vs. Oxycodone/Acetaminophen (Percocet)

Condition:   Pain Management
Interventions:   Drug: Morphine Sulfate;   Drug: Oxycodone;   Drug: Acetaminophen
Sponsor:   Antonios Likourezos
Completed

Thu, 23 Mar 2017 12:00:00 EDT

Comparison of Epidural Oxycodone and Epidural Morphine

Condition:   Pruritus
Interventions:   Drug: Opioid administration oxycodone;   Drug: Opioid administration morphine
Sponsor:   KK Women's and Children's Hospital
Completed

Wed, 29 Oct 2014 12:00:00 EDT

Pre- Versus Post-Incisional Epidural Morphine: Higher Postoperative Pain Perception and Extra Morphine Consumption

Condition:   Pain
Intervention:   Drug: normal saline 3 ml, morphine 3mg
Sponsor:   Tel-Aviv Sourasky Medical Center
Completed

Tue, 30 Mar 2010 12:00:00 EDT

Intravenous Paracetamol or Morphine for the Treatment of Acute Flank Pain

Condition:   Urolithiasis
Interventions:   Drug: paracetamol;   Drug: morphine;   Drug: Paracetamol;   Drug: Morphine
Sponsor:   Pamukkale University
Completed

Fri, 18 Mar 2011 12:00:00 EDT

Effect of Topical Morphine (Mouthwash) on Oral Pain Due to Chemo- and/or Radiotherapy Induced Mucositis

Conditions:   Cancer;   Mucositis
Interventions:   Drug: mouth wash with morphine;   Drug: placebo
Sponsor:   University Hospital, Geneva
Completed

Wed, 13 Feb 2008 12:00:00 EST

Effects of a Single Dose of Egalet® Morphine Combined With a Single Dose of Alcohol in Healthy Moderate Drinkers

Condition:   Pain
Intervention:   Drug: Morphine sulphate
Sponsor:   Egalet Ltd
Completed

Thu, 04 Dec 2008 12:00:00 EST

Randomized Control Trial of Buprenorphine vs. Morphine for the Treatment of Neonatal Opioid Withdrawal Syndrome (NOWS)

Condition:   Neonatal Opioid Withdrawal Syndrome
Interventions:   Drug: Buprenorphine or Placebo;   Drug: Morphine or Placebo
Sponsors:   Women and Infants Hospital of Rhode Island;   National Institute of General Medical Sciences (NIGMS)
Not yet recruiting

Thu, 02 Jul 2020 12:00:00 EDT

Efficacy of Multimodal Opioid Therapy During Hepatic Resection Surgery

Conditions:   Liver Dysfunction;   Pain
Interventions:   Drug: Morphine sulphate;   Drug: Morphine hydrochloride, remifentanil hydrochloride
Sponsor:   St Vincent's University Hospital, Ireland
Unknown status

Sun, 04 Nov 2007 12:00:00 EDT

Effect of Methylnaltrexone on the PK/PD Profiles of Ticagrelor in Patients Treated With Morphine

Condition:   Coronary Artery Disease
Interventions:   Drug: Methylnaltrexone;   Other: Placebo;   Drug: Morphine;   Drug: Ticagrelor
Sponsor:   University of Florida
Completed

Tue, 31 Mar 2015 12:00:00 EDT

Methadone Versus Morphine for Orthopedic Surgery Patients

Conditions:   Fracture;   Pain, Postoperative
Interventions:   Drug: Methadone;   Drug: Morphine
Sponsor:   University of Louisville
Completed

Mon, 04 May 2009 12:00:00 EDT

Comparison of One Morphine Sulfate Sustained-Release 200mg Capsule With Two 100 mg KADIAN Capsules Under Fasting Conditions

Condition:   Healthy
Interventions:   Drug: morphine sulfate sustained-release capsules;   Drug: KADIAN (morphine sulfate sustained-release) capsules
Sponsor:   Actavis Inc.
Completed

Thu, 25 Sep 2008 12:00:00 EDT

Comparison of One Morphine Sulfate Sustained-Release 200mg Capsule With Two 100 mg KADIAN Capsules Under Fed Conditions

Condition:   Healthy
Interventions:   Drug: morphine sulfate sustained-release capsules;   Drug: KADIAN
Sponsor:   Actavis Inc.
Completed

Thu, 25 Sep 2008 12:00:00 EDT

Visual Pain Score and Perfusion Index in Postoperative Patients

Condition:   Perfusion
Intervention:   Drug: Morphine
Sponsor:   Tokat Gaziosmanpasa University
Completed

Fri, 12 May 2017 12:00:00 EDT

Effect of Morphine, Tramadol, and Ketorolac on Postoperative Stress and Immune Responses

Condition:   Breast Cancer
Interventions:   Drug: Intravenous morphine sulphate;   Drug: Intravenous tramadol HCL;   Drug: Intravenous ketorolac tromethamine
Sponsor:   Assiut University
Unknown status

Thu, 21 May 2015 12:00:00 EDT

Comparison of Morphine and Fentanyl/Midazolam in Intensive Care Unit

Condition:   Respiratory Failure
Interventions:   Drug: Morphine infusion;   Drug: Fentanyl and Midazolam infusion
Sponsor:   Clínica de Los Andes IPS
Completed

Mon, 21 May 2012 12:00:00 EDT

The Analgesic Efficacy of Local Anaesthetic Wound Infiltration Versus Intrathecal Morphine for Total Knee Replacement

Condition:   Total Knee Replacement
Interventions:   Drug: Levobupivacaine;   Drug: Intrathecal morphine
Sponsor:   Cork University Hospital
Unknown status

Thu, 10 Mar 2011 12:00:00 EST

The Intrathecal Morphine for Nephrectomy

Condition:   Renal Cell Carcinoma
Interventions:   Drug: The intrathecal morphine injection;   Drug: The intravenous patient-controlled analgesia;   Drug: Demerol on demand
Sponsor:   Seoul National University Hospital
Completed

Thu, 28 Nov 2013 12:00:00 EST

Spinal Morphine in Robotic Assisted Radical Prostatectomy

Conditions:   Morphine;   Injections, Spinal;   Prostatectomy;   Patient Satisfaction
Interventions:   Drug: Morphine;   Drug: Lidocaine
Sponsor:   Maasstad Hospital
Completed

Wed, 05 Oct 2016 12:00:00 EDT

Comparison of Two Analgesic Strategies After Scheduled Caesarean

Condition:   Analgesia
Interventions:   Drug: Rachianesthesia;   Drug: Sodium Chloride Injection;   Drug: Morphine
Sponsor:   GCS Ramsay Santé pour l'Enseignement et la Recherche
Recruiting

Tue, 16 Feb 2021 12:00:00 EST

Buprenorphine for Treatment of Neonatal Abstinence Syndrome in Infants With In Utero Exposure to Benzodiazepines

Condition:   Neonatal Abstinence Syndrome
Interventions:   Drug: oral morphine;   Drug: sublingual buprenorphine
Sponsor:   Thomas Jefferson University
Completed

Thu, 23 Aug 2012 12:00:00 EDT

Analgesia and Wound Healing Assessment Following Topical Morphine Applied to Patients With Cutaneous Cancer Related Pain

Conditions:   Ulcer;   Wounds and Injuries
Intervention:   Drug: topical morphine
Sponsors:   Soroka University Medical Center;   Israel Cancer Association
Withdrawn

Wed, 22 Mar 2006 12:00:00 EST

Abuse Potential Assessment of Intranasally Administered EMBEDA Compared To Morphine Sulfate Controlled Release And Placebo

Conditions:   Narcotic Abuse;   Opioid-related Disorders;   Analgesia;   Chronic Pain
Interventions:   Drug: Placebo;   Drug: EMBEDA - morphine sulfate/ naltrexone hydrochloride;   Drug: morphine sulfate CR crushed.
Sponsor:   Pfizer
Completed

Thu, 10 May 2012 12:00:00 EDT

Comparison of the Analgesic Effect Between Intrathecal Morphine and IV-fentanyl Patient Controlled Analgesia (ITM-IVPCA) and Epidural PCA (PCEA) in Patients Undergoing Gastrectomy -Randomized Allocation Study-

Condition:   Gastric Cancer
Interventions:   Drug: morphine;   Drug: Ropivacaine
Sponsor:   Yonsei University
Completed

Thu, 04 Nov 2010 12:00:00 EDT

Magnetic Seizure Therapy In Bipolar Depression (MST-BpD)

Condition:   Bipolar Disorder
Interventions:   Device: MST;   Device: ECT
Sponsor:   The University of Texas Health Science Center, Houston
Recruiting

Fri, 06 Sep 2019 12:00:00 EDT

Long Thoracic Nerve Blockade for Pain Treatment After Video-Assisted Thoracoscopic Surgery

Conditions:   Nerve Block;   Video-Assisted Thoracic Surgery
Interventions:   Drug: Morphine Sulfate;   Drug: Bupivacaine
Sponsor:   Bursa Yüksek İhtisas Education and Research Hospital
Unknown status

Fri, 30 Mar 2018 12:00:00 EDT

Use of Intrathecal Hydromorphone in Elective Cesarean Deliveries

Condition:   Pain
Interventions:   Drug: Hydromorphone;   Drug: Morphine
Sponsors:   Grace Shih, MD;   Masimo Corporation
Completed

Fri, 31 May 2013 12:00:00 EDT

Vital Signs-Integrated Patient-Assisted Intravenous Opioid Analgesia for Post Surgical Pain

Conditions:   Pain;   Respiratory Depression
Interventions:   Device: VPIA pump;   Drug: Morphine
Sponsor:   KK Women's and Children's Hospital
Recruiting

Mon, 08 Jul 2019 12:00:00 EDT

Bioavailability and Effectiveness of Transdermally Administered Morphine

Conditions:   Cancer;   Pain
Intervention:   Drug: morphine
Sponsors:   Alberta Health Services;   Tom Baker Cancer Centre
Completed

Tue, 02 Aug 2005 12:00:00 EDT

Inflammatory Responses to Acute and Chronic Opioid Exposure in Humans

Condition:   Inflammation
Intervention:   Drug: Morphine Sulfate
Sponsor:   Stanford University
Terminated

Mon, 17 Dec 2012 12:00:00 EST

Comparison of Intrathecal Morphine With the Quadratus Lumborum Type 2 Block for Post-operative Analgesia Following Elective Caesarean Section (QLBvITM Study)

Conditions:   Cesarean Section;   Pain, Acute
Interventions:   Procedure: Intrathecal morphine as well as local anaesthetic in Blocks;   Procedure: Intrathecal morphine as well as saline in Block;   Procedure: Saline intrathecal as well as saline in Blocks;   Procedure: Saline intrathecal as well as local anaesthetic in Blocks
Sponsors:   Dr Willem Basson;   Sunshine Coast Hospital and Health Service
Withdrawn

Wed, 30 Aug 2017 12:00:00 EDT

Intermittent Epidural Bolus Versus Epidural Infusion for Posterior Spinal Fusion After Adolescent Idiopathic Scoliosis

Condition:   Pain
Interventions:   Drug: Intermittent bolus epidural morphine;   Drug: continuous epidural morphine
Sponsor:   Inonu University
Completed

Fri, 29 Jan 2016 12:00:00 EST

A Health Economic Trial in Adult Patients Undergoing Open Colectomy MA402S23B301

Condition:   Bowel Obstruction
Interventions:   Drug: morphine sulfate;   Drug: bupivacaine liposome extended-release injectable suspension
Sponsors:   Pacira Pharmaceuticals, Inc;   Registrat-Mapi
Terminated

Tue, 10 Jan 2012 12:00:00 EST

A Randomized, Double-blind Comparison of Morphine and Sufentanil for Prehospital Traumatic Severe Acute Pain

Condition:   Acute Pain
Interventions:   Drug: Sufentanil;   Drug: Morphine
Sponsor:   University Hospital, Toulouse
Completed

Fri, 11 Apr 2008 12:00:00 EDT

Comparison of One Morphine Sulfate Sustained-Release 200 mg Capsule With Two 100 mg KADIAN Capsules on Applesauce

Condition:   Healthy
Interventions:   Drug: morphine sulfate sustained-release capsules;   Drug: KADIAN (morphine sulfate sustained-release) capsules
Sponsor:   Actavis Inc.
Completed

Thu, 25 Sep 2008 12:00:00 EDT

Geriatric Ketamine for Pain Management Study

Condition:   Pain
Interventions:   Drug: Morphine;   Drug: Ketamine
Sponsor:   Antonios Likourezos
Completed

Wed, 03 Feb 2016 12:00:00 EST

Non-Opiate Treatment After Prenatal Opiate Exposure to Prevent Postnatal Injury to the Young Brain

Condition:   Neonatal Abstinence Syndrome
Interventions:   Drug: Clonidine;   Drug: Morphine
Sponsors:   Henrietta Bada;   National Institute on Drug Abuse (NIDA)
Recruiting

Thu, 11 Jan 2018 12:00:00 EST

Intrathecal Morphine for Radical Robot Assisted Prostatectomy (TORNADO)

Condition:   Catheter Related Complication
Interventions:   Drug: intrathecal infusion;   Drug: Intravenous Infusion;   Drug: Ropivacaine injection
Sponsor:   Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Completed

Wed, 24 Mar 2021 12:00:00 EDT

Efficacy of Intranasal Fentanyl at Reducing Pain During Abscess Incision and Drainage (I&D) in Children

Conditions:   Abscess;   Pain
Interventions:   Drug: Intranasal Fentanyl;   Drug: Intravenous Morphine
Sponsor:   Columbia University
Completed

Thu, 08 Mar 2012 12:00:00 EST

Vital-signs-integrated Patient-assisted Intravenous Opioid Analgesia

Condition:   Respiratory Depression
Interventions:   Device: VPIA analgesia;   Drug: Morphine
Sponsor:   KK Women's and Children's Hospital
Active, not recruiting

Fri, 17 Jun 2016 12:00:00 EDT

Buprenorphine for the Treatment of Neonatal Abstinence Syndrome

Condition:   Neonatal Abstinence Syndrome
Interventions:   Drug: buprenorphine;   Drug: Oral morphine solution
Sponsors:   Thomas Jefferson University;   National Institute on Drug Abuse (NIDA)
Completed

Mon, 27 Aug 2007 12:00:00 EDT

Intra Nasal Sufentanil Versus Intravenous Morphine for Acute Severe Traumatic Pain Analgesia in Emergency Setting

Conditions:   Severe Traumatic Pain;   Numeric Pain Rating Scale > 5 / 10
Interventions:   Drug: Morphine;   Drug: Sufentanil;   Drug: Placebo
Sponsors:   University Hospital, Grenoble;   Fondation Apicil;   SFMU
Completed

Mon, 24 Mar 2014 12:00:00 EDT

Cannabidiol, Morphine, Pain

Conditions:   CBD;   Chronic Pain
Interventions:   Drug: Immediate-release Oral Morphine Sulfate Tablets;   Other: Thermal and Pressure Nociceptive Sensitivity
Sponsor:   Wayne State University
Recruiting

Wed, 24 Jul 2019 12:00:00 EDT

Comparison of A Single Dose Combination of Methadone and Morphine With Morphine Alone for Treating Post-operative Pain

Condition:   Pain
Interventions:   Drug: Methadone;   Drug: methadone and morphine
Sponsor:   Memorial Sloan Kettering Cancer Center
Completed

Fri, 02 Sep 2005 12:00:00 EDT

Postoperative Urinary Retention in Orthopedic Patients

Conditions:   Urinary Retention;   Anesthesia, Spinal;   Orthopedic Procedures;   Nerve Block
Interventions:   Procedure: spinal anesthesia with morphine;   Procedure: spinal anesthesia without morphine + peripheral nerve block
Sponsor:   Hospital de Clinicas de Porto Alegre
Completed

Fri, 06 Mar 2020 12:00:00 EST

Incidence of Brachial Plexus Injury After Rotator Cuff Repair With Continuous Interscalene Block

Condition:   Brachial Plexus Injury
Interventions:   Procedure: Continuous interscalene block;   Procedure: PCA morphine
Sponsor:   Centre Hospitalier Universitaire Vaudois
Withdrawn

Wed, 13 Apr 2011 12:00:00 EDT

Comparison of Two KADIAN 10 mg Capsules to a KADIAN 20 mg Capsule Under Fed Conditions

Condition:   Healthy
Interventions:   Drug: morphine sulfate extended-release capsules;   Drug: KADIAN (morphine sulfate extended-release) capsules
Sponsor:   Actavis Inc.
Completed

Thu, 25 Sep 2008 12:00:00 EDT

Anti-suicidal Effects of Buprenorphine in Opioid Use Disorder

Conditions:   Opioid-use Disorder;   Suicidal Ideation
Interventions:   Drug: Buprenorphine/Naloxone 8/2 milligram (mg) Sublingual Film;   Drug: Morphine Sulfate 30 mg
Sponsor:   New York State Psychiatric Institute
Withdrawn

Tue, 21 Jan 2020 12:00:00 EST

Clonidine and Morphine in Caudal Anesthesia

Condition:   Postoperative Pain
Interventions:   Drug: Clonidine;   Drug: Morphine;   Drug: Bupivacaine plus clonidine and morphine;   Drug: Bupivacaine
Sponsors:   Federal University of Minas Gerais;   Santa Casa de Misericórdia de Belo Horizonte
Completed

Tue, 06 May 2008 12:00:00 EDT

Efficacity, Safety and Cost of Intravenous Morphine Titration Alone or Combined to Ketamine

Condition:   Postoperative Pain
Intervention:   Drug: Ketamine
Sponsor:   Assistance Publique - Hôpitaux de Paris
Completed

Thu, 17 Jun 2010 12:00:00 EDT

Comparison of Two KADIAN 10 mg Capsules to a KADIAN 20 mg Capsule Under Fasted Conditions

Condition:   Healthy
Interventions:   Drug: morphine sulfate extended-release capsules;   Drug: KADIAN (morphine sulfate extended-release) capsules
Sponsor:   Actavis Inc.
Completed

Thu, 25 Sep 2008 12:00:00 EDT

Morphine in Acute Abdominal Pain

Condition:   Abdominal Pain
Intervention:   Drug: Morphine
Sponsor:   Akdeniz University
Completed

Wed, 28 Apr 2010 12:00:00 EDT

A Comparison of the Addiction Liability of Hydrocodone and Sustained Release Morphine

Condition:   Chronic Pain
Interventions:   Behavioral: Markers of Abuse Liability, Neuropsych Testing, and Cue Reactivity;   Drug: ER Morphine;   Drug: hydrocodone plus acetaminophen;   Drug: placebo
Sponsor:   University of California, Davis
Completed

Thu, 13 Apr 2006 12:00:00 EDT

Management of Pain Post Hepatectomy : Infiltration of Local Anesthetics Versus Continuous Spinal Analgesia .

Condition:   Pain, Postoperative
Interventions:   Drug: intrathecal morphine;   Drug: Morphine PCA;   Drug: Ropivacaine infiltration
Sponsor:   University Hospital, Lille
Active, not recruiting

Thu, 03 Aug 2017 12:00:00 EDT

Comparison of the Safety of Q8003 Versus Morphine Equivalent Doses of Its Components (Oxycodone and Morphine) in Bunionectomy Patients

Condition:   Postoperative Pain
Interventions:   Drug: Q8003 (morphine sulfate and oxycodone hydrochloride);   Drug: Morphine sulfate;   Drug: Oxycodone HCl
Sponsor:   QRxPharma Inc.
Completed

Thu, 20 Jan 2011 12:00:00 EST

Safety and Efficacy of Intrathecally Administered Magnesium Sulfate

Conditions:   Abdominal Cancer;   Abdominal Pain
Interventions:   Procedure: intrathecal morphine+LA;   Procedure: intrathecal morphine+LA+ Mg sulp. 50;   Procedure: intrathecal morphine+LA+ Mg sulp. 100
Sponsor:   South Egypt Cancer Institute
Completed

Thu, 08 Mar 2018 12:00:00 EST

Topical Morphine for Stomatitis-related Pain Induced by Chemotherapy

Conditions:   Pain;   Mucositis
Interventions:   Drug: morphine solution for injection;   Drug: Placebo;   Drug: morphine mouthwash
Sponsors:   Danish University of Pharmaceutical Sciences;   Copenhagen University Hospital, Denmark
Completed

Fri, 28 Jul 2006 12:00:00 EDT

Drug Drug Interaction Study With Gabapentin Enacarbil and Morphine

Condition:   Restless Legs Syndrome
Interventions:   Drug: morphine Placebo;   Drug: GEn 600 mg;   Drug: Morphine;   Drug: GEn Placebo
Sponsor:   XenoPort, Inc.
Completed

Tue, 22 Nov 2011 12:00:00 EST

A Health Economic Trial in Adult Patients Undergoing Open Colectomy MA402S23B302

Condition:   Bowel Obstruction
Interventions:   Drug: IV morphine sulfate;   Drug: EXPAREL (bupivacaine liposome injectable suspension)
Sponsors:   Pacira Pharmaceuticals, Inc;   Registrat-Mapi
Terminated

Tue, 10 Jan 2012 12:00:00 EST

Local Infiltration Analgesia or Intrathecal Morphine in Total Knee Arthroplasty

Condition:   Osteoarthritis
Interventions:   Drug: ropivacaine, ketorolac and epinephrine;   Drug: morphine
Sponsor:   Region Örebro County
Unknown status

Thu, 08 Oct 2009 12:00:00 EDT

A Study to Evaluate the Effectiveness and Safety of CG5503 (Tapentadol) in the Treatment of Chronic Tumor Related Pain Compared With Placebo and Morphine

Conditions:   Pain;   Neoplasm;   Cancer
Interventions:   Drug: Tapentadol in the Titration Phase;   Drug: Morphine in the Maintenance Phase;   Drug: Matching Placebo in the Maintenance Phase after Tapentadol in the Titration Phase;   Drug: Tapentadol in the Maintenance Phase;   Drug: Morphine in the Titration Phase
Sponsors:   Grünenthal GmbH;   Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Terminated

Mon, 23 Jul 2007 12:00:00 EDT

Tramadol Versus Placebo and Morphine in the Management of Post-Operative Pain Abdominoplasty

Condition:   Pain Management
Interventions:   Drug: Tramadol;   Drug: Morphine;   Other: Placebo
Sponsor:   Avenue Therapeutics, Inc.
Active, not recruiting

Thu, 13 Dec 2018 12:00:00 EST

The Effect of Intravenous Nalbuphine on PONV With Intrathecal Morphine in Abdominoplasty.

Condition:   Abdominal Obesity
Interventions:   Drug: Intrathecal Morphine;   Drug: Intrathecal Morphine + Intravenous Nalbuphine
Sponsor:   Assiut University
Unknown status

Wed, 26 Dec 2018 12:00:00 EST

The Analgesic Effect of Combined Treatment With Intranasal S-ketamine and Intranasal Midazolam

Conditions:   Analgesia, Patient-controlled;   Spinal Stenosis
Interventions:   Drug: s-ketamine & midazolam;   Drug: Morphine PCA
Sponsor:   University Hospital, Basel, Switzerland
Completed

Wed, 12 Jan 2011 12:00:00 EST

A Study to Evaluate Tapentadol (CG5503) in the Treatment of Chronic Tumor-Related Pain Compared With Placebo and Morphine

Conditions:   Tumor;   Pain
Interventions:   Drug: Tapentadol Extended Release;   Drug: Matching Placebo after Tapentadol in the Titration Phase.;   Drug: Morphine Sulphate Controlled Release
Sponsors:   Grünenthal GmbH;   Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Completed

Fri, 11 May 2007 12:00:00 EDT

Postoperative Pain Therapy With Hydromorphone TCI-PCA vs. Morphine PCA

Condition:   Acute Postoperative Pain
Interventions:   Drug: Hydromorphone;   Drug: Morphine
Sponsors:   University of Erlangen-Nürnberg Medical School;   German Federal Ministry of Education and Research
Completed

Fri, 26 Jun 2015 12:00:00 EDT

Efficacy of Transdermal Fentanyl Patches in Relief of Acute Postoperative Pain After Mastectomy

Condition:   Breast Cancer Female
Interventions:   Drug: The Transdermal Therapeutic System-Fentanyl (TTS-F);   Device: Intravenous patient-controlled analgesia (PCA) morphine
Sponsor:   South Egypt Cancer Institute
Unknown status

Mon, 13 Feb 2017 12:00:00 EST

Combination Trial of Intravenous Paracetamol - Morphine for Treating Acute Renal Colic in Emergency Setting: An Optimum Treatment

Condition:   Renal Colic
Interventions:   Drug: Paracetamol+Morphine;   Drug: Dexketoprofen plus Morphine;   Drug: Placebo plus Morphine
Sponsor:   Akdeniz University
Completed

Wed, 06 Mar 2019 12:00:00 EST

Dexmedetomidine for Postoperative Analgesia After Bariatric Surgery

Conditions:   Obesity;   Sleep Apnea;   Diabetes;   Hypertension
Interventions:   Drug: Dexmedetomidine;   Drug: Morphine
Sponsor:   American University of Beirut Medical Center
Completed

Mon, 11 Aug 2014 12:00:00 EDT

Quadratus Lumborum in Cesarean Section Trial

Condition:   Postoperative Analgesia
Intervention:   Procedure: Quadratus Lumborum Block
Sponsor:   University of Sao Paulo General Hospital
Unknown status

Mon, 17 Sep 2018 12:00:00 EDT

A Pharmacokinetic (PK) Study of Extended-Release Epidural Morphine in Upper Abdominal Surgery

Condition:   Postoperative Pain
Intervention:   Drug: DepoDur (extended-release epidural morphine)
Sponsors:   EKR Therapeutics, Inc;   Pacira Pharmaceuticals, Inc
Completed

Wed, 06 Aug 2008 12:00:00 EDT

Very Low Dose Caudal Morphine for Postoperative Pain Management

Condition:   Caudal Anesthesia
Intervention:   Procedure: Caudal block
Sponsor:   University of Oklahoma
Completed

Tue, 14 Jul 2009 12:00:00 EDT

A Comparison of Analgesic Efficacy Between a Single Dose of ORG 28611, Morphine, and Placebo After Dental Impaction Surgery (Study P05800)

Condition:   Analgesia
Interventions:   Drug: Org 28611;   Drug: morphine sulfate;   Drug: Placebo
Sponsor:   Merck Sharp & Dohme Corp.
Terminated

Fri, 31 Oct 2008 12:00:00 EDT

Efficacy of Intravenous Ibuprofen and Paracetamol on Postoperative Pain and Morphine Consumption in Lumbar Disc Surgery

Condition:   Postoperative Pain Management
Interventions:   Drug: Morphine Sulfate;   Drug: Intravenous paracetamol;   Drug: Intravenous ibuprofen
Sponsor:   Inonu University
Completed

Mon, 19 Feb 2018 12:00:00 EST

Effect of Early Morphine Administration on the Development of Acute Opioid Tolerance During Pediatric Scoliosis Surgery

Condition:   Scoliosis
Interventions:   Drug: Morphine;   Other: Saline
Sponsor:   The Hospital for Sick Children
Completed

Wed, 20 Aug 2008 12:00:00 EDT

A Study of OROS Hydromorphone HCL vs Morphine in Cancer Pain Patients.

Conditions:   Pain;   Analgesics, Opioid
Intervention:   Drug: OROS hydromorphone HCL ; Morphine sulfate
Sponsor:   Alza Corporation, DE, USA
Completed

Wed, 13 Dec 2006 12:00:00 EST

Pain Medicine for Wound Care Procedures

Conditions:   Wound Care;   Pain Intensity;   Hyperalgesia;   Nausea;   Vomiting;   Hallucinations
Interventions:   Drug: morphine plus saline;   Drug: morphine plus ketamine
Sponsor:   University of California, San Francisco
Completed

Thu, 19 Jun 2008 12:00:00 EDT

Ticagrelor and Intracoronary Morphine in Patients Undergoing Primary Percutaneous Coronary Intervention

Condition:   ST-Segment Elevation Myocardial Infarction
Interventions:   Drug: Ticagrelor;   Drug: Clopidogrel;   Drug: Morphine Sulfate;   Drug: Saline
Sponsor:   Hyeon-Cheol Gwon
Unknown status

Fri, 30 Nov 2012 12:00:00 EST

Postoperative Pain Control After Hip Hemiarthroplasty: Intrathecal Morphine vs Periarticular Infiltration of Bupivacaine

Condition:   Femoral Neck Fracture
Interventions:   Drug: morphine;   Other: control;   Drug: Bupivacaine
Sponsor:   Mahidol University
Terminated

Wed, 13 Oct 2010 12:00:00 EDT

Measurement of the Efficacy of MORPHINE in the Early Management of Dyspnea in COVID-19 Positive Patients

Conditions:   Patients Hospitalized in the Hospices Civils of Lyon;   COVID-19 Disease;   Moderate to Severe Dyspnea;   Without Resuscitation Objective Management
Intervention:   Other: No intervention / Compare the difference in respiratory rate between H0 and H12 of the initiation of morphine between the control and interventional groups
Sponsor:   Hospices Civils de Lyon
Recruiting

Fri, 21 Aug 2020 12:00:00 EDT

Role of Methadone As Co-Opioid Analgesic

Condition:   Pain
Interventions:   Drug: Morphine;   Drug: Methadone
Sponsor:   M.D. Anderson Cancer Center
Terminated

Thu, 15 Nov 2007 12:00:00 EST

Extended-release Epidural Morphine for Acute Post-operative Analgesia Following Selective Dorsal Rhizotomy in Children

Condition:   Spastic Cerebral Palsy
Interventions:   Drug: Extended-release Epidural morphine (EREM) 80;   Drug: Extended-release Epidural Morphine (EREM) 120;   Drug: Control: Saline
Sponsor:   Washington University School of Medicine
Terminated

Mon, 10 Aug 2009 12:00:00 EDT

Spinal Analgesia for Colonic Resection Using an Enhanced Recovery After Surgery (ERAS) Program

Conditions:   Colon Cancer;   Inflammatory Bowel Diseases;   Diverticulitis
Interventions:   Drug: Spinal analgesia;   Drug: Patient Control Analgesia (PCA) Morphine
Sponsor:   McGill University Health Centre/Research Institute of the McGill University Health Centre
Completed

Tue, 22 Nov 2011 12:00:00 EST

Morphine Titration by Patient Self-controlled by a Mechanical Device Versus Administration by the Nurse for Patients With Severe Acute Pain in the Emergency Department

Condition:   Acute Pain
Intervention:   Device: Titration of morphine by Patient Controlled Analgesy
Sponsor:   University Hospital, Angers
Completed

Mon, 02 Jun 2014 12:00:00 EDT

Postoperative Pain Control After Kidney Surgery : a Comparison of Intrathecal Morphine Plus PCA and PCA Only

Condition:   Postoperative Pain
Intervention:   Drug: spinal morphine
Sponsor:   Khon Kaen University
Unknown status

Tue, 20 Sep 2005 12:00:00 EDT

Magnetic Seizure Therapy for the Treatment of Borderline Personality Disorder

Condition:   Borderline Personality Disorder
Interventions:   Device: MagPro MST with Cool TwinCoil;   Behavioral: DBT
Sponsor:   Centre for Addiction and Mental Health
Active, not recruiting

Tue, 05 Dec 2017 12:00:00 EST

Efficacy of Intravenous Paracetamol and Ibuprofen on Postoperative Pain and Morphine Consumption in Hysterectomy

Condition:   Postoperative Pain Management
Interventions:   Drug: Morphine Sulfate;   Drug: Intravenous paracetamol;   Drug: Intravenous ibuprofen;   Drug: Morphine
Sponsor:   Inonu University
Enrolling by invitation

Thu, 31 Dec 2020 12:00:00 EST

Ibuprofen and Opioid (Morphine or Diamorphine) for Acute Pain in Sickle Cell Disease - Sickle With Ibuprofen & Morphine

Condition:   Sickle Cell Disease
Interventions:   Drug: Ibuprofen;   Drug: Placebo;   Drug: Diamorphine or Morphine
Sponsors:   London North West Healthcare NHS Trust;   Medical Research Council CTU
Terminated

Mon, 13 Apr 2009 12:00:00 EDT

Morphine Mouthwash for Management of Oral Mucositis in Patients With Head and Neck Cancer

Condition:   Stomatitis
Interventions:   Drug: 2% morphine solution;   Drug: Magnesium aluminum hydroxide;   Drug: 2% viscous lidocaine;   Drug: Diphenhydramine
Sponsor:   Isfahan University of Medical Sciences
Completed

Tue, 23 Apr 2013 12:00:00 EDT

Evaluation of Preoperative Use of Pregabalin on Postoperative Analgesia After Laparoscopic Colorectal Surgery

Condition:   Postoperative Pain
Interventions:   Drug: Pregabalin;   Drug: Placebo;   Drug: Morphine
Sponsors:   Larissa University Hospital;   University of Thessaly
Completed

Thu, 12 Sep 2013 12:00:00 EDT

Parent/Nurse Controlled Analgesia in the Neonatal Intensive Care Unit

Conditions:   Abdominal Surgery;   Thoracic Surgery
Intervention:   Drug: Morphine
Sponsors:   Medical College of Wisconsin;   Children's Hospital and Health System Foundation, Wisconsin
Completed

Thu, 04 Apr 2013 12:00:00 EDT

Intrathecal Ketorolac in Patients With Intrathecal Morphine Dose Escalation

Condition:   Pain
Interventions:   Drug: ketorolac;   Drug: morphine
Sponsor:   Wake Forest University Health Sciences
Withdrawn

Fri, 07 Jul 2006 12:00:00 EDT

Analgesic Tolerance to Repeated Doses of Subcutaneous Morphine

Condition:   Healthy Volunteers
Intervention:   Drug: intramuscular injections of morphine
Sponsor:   University of California, San Francisco
Completed

Mon, 21 Nov 2005 12:00:00 EST

Paravertebral Morphine Versus Dexmedetomidine on Acute and Chronic Postmastectomy Pain

Conditions:   Acute Pain;   Chronic Pain
Interventions:   Drug: bupivicaine;   Drug: morphine;   Drug: Dexmedetomidine
Sponsor:   Assiut University
Unknown status

Tue, 18 Oct 2016 12:00:00 EDT

A Safety and Efficacy Study of Sufentanil Transdermal System in Patients With Chronic Pain Due to Cancer

Condition:   Chronic Pain
Interventions:   Drug: Sufentanil;   Drug: Sustained Release Morphine Sulfate
Sponsor:   Labtec GmbH
Withdrawn

Wed, 22 Jul 2009 12:00:00 EDT

A Study Comparing Recurrent Use of MSIR, Percocet, and Vicodin at Discharge From the ED

Condition:   Pain
Interventions:   Drug: Morphine Sulfate Immediate Release;   Drug: Oxycodone/Acetaminophen;   Drug: Hydrocodone/Acetaminophen
Sponsor:   Antonios Likourezos
Withdrawn

Fri, 18 May 2018 12:00:00 EDT

Morphine Slow-release Capsules in Substitution Therapy

Condition:   Opiate Dependent
Interventions:   Drug: Sevre-Long™;   Drug: Slow release oral morphine;   Drug: Methadone
Sponsor:   Mundipharma Medical Company
Completed

Tue, 02 Mar 2010 12:00:00 EST

A Prospective Comparison of Methadone, Fentanyl, and Morphine for Post-laparotomy Epidural Analgesia

Condition:   Post Laparotomy Pain Treatment
Interventions:   Drug: epidural morphine via PCEA;   Drug: epidural fentanyl via PCEA;   Drug: epidural methadone via PCEA;   Drug: intravenous morphine via PCA
Sponsor:   Hadassah Medical Organization
Unknown status

Thu, 11 Apr 2013 12:00:00 EDT

Intrathecal Opioids for Colorectal Resection

Conditions:   Colorectal Surgery;   Pain, Postoperative;   Analgesic, Opioid
Interventions:   Drug: Morphine;   Drug: Hydromorphone
Sponsor:   Mayo Clinic
Recruiting

Fri, 12 Feb 2021 12:00:00 EST

Translation and Validation of the German Version of the Toronto Extremity Salvage Score (TESS) and Musculoskeletal Tumor Society (MSTS)

Condition:   Sarcoma
Intervention:   Other: Questionaire TESS and MSTS
Sponsor:   Medical University Innsbruck
Not yet recruiting

Tue, 31 Mar 2020 12:00:00 EDT

Comparative Pain Control Between 0.2 or 0.3 Spinal Morphine and 0.25 or 0.5 % Bupivacaine for FNB After TKA

Conditions:   Post Operative Pain;   Total Knee Replacement
Interventions:   Drug: morphine and bupivacaine;   Drug: spinal morphine and marcaine
Sponsors:   Mahidol University;   Siriraj Hospital
Completed

Fri, 21 Nov 2008 12:00:00 EST

Quadratus Lumborum Block for Post-Cesarean Analgesia

Condition:   Postoperative Pain
Interventions:   Procedure: Quadratus Lumborum Block;   Procedure: Sham Block;   Drug: Intrathecal Morphine;   Drug: Intrathecal Saline
Sponsor:   Lawson Health Research Institute
Unknown status

Thu, 15 Jan 2015 12:00:00 EST

Investigating the Safety of Post-surgical Analgesics in Children With Obstructive Sleep Apnea

Condition:   Pediatric Obstructive Sleep Apnea Syndrome
Interventions:   Drug: Morphine;   Drug: Ibuprofen
Sponsors:   Hamilton Health Sciences Corporation;   The Hospital for Sick Children;   University of Western Ontario, Canada
Unknown status

Fri, 07 Sep 2012 12:00:00 EDT

NEUROIMPA - Intraarticular Application of Opioids in Chronic Arthritis of the Knee Joint

Condition:   Knee Arthritis
Interventions:   Drug: Morphine Sulfate;   Drug: Triamcinolone;   Drug: placebo
Sponsors:   Hildrun Haibel;   DLR German Aerospace Center
Active, not recruiting

Fri, 18 Nov 2016 12:00:00 EST

Comparison of Oral Morphine Versus Nasal Ketamine Spray With Chitosan in Cancer Pain Outpatients

Conditions:   Cancer: Breakthrough Pain;   Cancer: Extreme Pain on Movement
Interventions:   Drug: Morphine;   Drug: Ketamine;   Drug: Placebo;   Drug: Chitosan
Sponsor:   University Hospital, Basel, Switzerland
Terminated

Thu, 29 Oct 2015 12:00:00 EDT

Magnetic Seizure Therapy (MST) for Severe Mood Disorder

Condition:   Depression
Interventions:   Device: Thymatron;   Device: Magstim Theta
Sponsors:   Sarah Lisanby;   Duke University;   University of Texas Southwestern Medical Center;   Stanley Medical Research Institute
Completed

Wed, 20 Jun 2007 12:00:00 EDT

Double Blind Randomized, Monocentric, Cross-over, Placebo-controlled Study to Evaluate the Effect of Morphine and Naloxone on Motivation (MBBAnalgesic)

Condition:   Healthy
Interventions:   Drug: 50 mL of sodium chloride (0,9%);   Drug: Morphine 0,05mg/kg;   Drug: Naloxone 10mg
Sponsor:   Institut National de la Santé Et de la Recherche Médicale, France
Completed

Fri, 17 Oct 2014 12:00:00 EDT

A Within Subject Comparison of Opioid Withdrawal in Opioid Dependent Individuals

Conditions:   Opioid Abuse;   Opioid Dependence
Interventions:   Drug: buprenorphine;   Drug: morphine
Sponsors:   Johns Hopkins University;   National Institute on Drug Abuse (NIDA)
Completed

Thu, 03 Jun 2010 12:00:00 EDT

Multimodal Analgesic Treatment Versus Traditional Morphine Analgesia After Cardiac Surgery

Conditions:   Analgesia;   Postoperative Pain
Interventions:   Drug: Ibuprofen;   Drug: Gabapentin;   Drug: Morphine;   Drug: Paracetamol
Sponsor:   Rigshospitalet, Denmark
Completed

Mon, 21 Oct 2013 12:00:00 EDT

Comparison of the Efficacy and Safety of NALDEBAIN With Conventional Treatment After Laparoscopic Cholecystectomy

Condition:   Pain, Postoperative
Interventions:   Drug: Naldebain;   Drug: Morphine
Sponsor:   Cathay General Hospital
Completed

Fri, 19 Oct 2018 12:00:00 EDT

Standard Pain Control or Intrathecal Therapy in Controlling Pain in Patients With Locally Advanced, Unresectable, or Metastatic Pancreatic Cancer

Conditions:   Pain;   Pancreatic Cancer
Interventions:   Drug: morphine sulfate;   Device: Medtronic intrathecal pump
Sponsors:   Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins;   National Cancer Institute (NCI)
Terminated

Thu, 17 Apr 2008 12:00:00 EDT

Patients-Controlled Epidural Analgesia After Gastric Bypass for Morbid Obesity Using Morphine-Levobupivacaine Regimens

Conditions:   Morbid Obesity;   Postoperative Pain;   Postoperative Bowel Function;   Postoperative Ambulation
Interventions:   Drug: GROUP A : 0 mg MORPHINE-0.1% LEVOBUPIVACAINE;   Drug: GROUP B : 1 mg MORPHINE- 0.1% LEVOBUPIVACAINE;   Drug: GROUP C : 2 mg MORPHINE-0.1% LEVOBUPIVACAINE;   Drug: GROUP D : 0 mg MORPHINE- 0.2% LEVOBUPIVACAINE;   Drug: GROUP E : 1 mg MORPHINE-0.2 % LEVOBUPIVACAINE;   Drug: GROUP F : 2 mg MORPHINE- 0.2% LEVOBUPIVACAINE
Sponsor:   University of Patras
Completed

Tue, 30 Nov 2010 12:00:00 EST

Effect of Bilateral Quadratus Lumborum Block for Pain Relief in Patients With Cesarean Section

Conditions:   Caesarean Section;   Spinal Anesthesia;   Quadratus Lumborum Block;   Analgesia
Interventions:   Drug: Intrathecal morphine;   Drug: Bilateral Quadratus Lumborum Block;   Drug: Intrathecal morphine with bilateral Quadratus Lumborum Block
Sponsor:   Mahidol University
Completed

Mon, 26 Jun 2017 12:00:00 EDT

Improving Outcomes in Neonatal Abstinence Syndrome

Conditions:   Neonatal Abstinence Syndrome;   Neonatal Opioid Withdrawal
Interventions:   Drug: Neonatal Morphine Solution;   Drug: Methadone;   Drug: Phenobarbital
Sponsor:   Tufts Medical Center
Completed

Wed, 09 Oct 2013 12:00:00 EDT

Immediate-Release Oxycodone Capsules Study in Cancer Pain

Condition:   Cancer
Interventions:   Drug: Oxycodone;   Drug: Morphine
Sponsor:   Mundipharma (China) Pharmaceutical Co. Ltd
Completed

Thu, 30 Aug 2012 12:00:00 EDT

Efficacy of Buprenorphine for Treatment of Acute Pain

Condition:   Acute Pain
Interventions:   Drug: Buprenorphine;   Drug: Morphine
Sponsor:   Tehran University of Medical Sciences
Completed

Thu, 17 Feb 2011 12:00:00 EST

Adult Patients Undergoing Open Colectomy MA402S23B303

Condition:   Bowel Obstruction
Interventions:   Drug: IV morphine sulfate;   Drug: EXPAREL (bupivacaine liposome injectable suspension)
Sponsors:   Pacira Pharmaceuticals, Inc;   Registrat-Mapi
Completed

Tue, 10 Jan 2012 12:00:00 EST

Methadone in Cystectomy Patients

Conditions:   Pain, Postoperative;   Postoperative Complications;   Pathologic Processes;   Bladder Cancer;   Pain;   Signs and Symptoms;   Neurologic Manifestations;   Neurologic Symptoms;   Side Effect of Drug
Interventions:   Drug: Methadone;   Drug: Morphine
Sponsor:   University of Aarhus
Recruiting

Fri, 17 Jul 2020 12:00:00 EDT

Intranasal Ketamine for Acute Traumatic Pain

Condition:   Acute Pain
Interventions:   Drug: Ketamine Hydrochloride;   Drug: Morphine
Sponsor:   Tel Aviv Medical Center
Completed

Wed, 29 Jun 2016 12:00:00 EDT

Incidence of Postoperative Delirium in Cancer Patients After Laparoscopic Surgery in Trendelenburg Position

Conditions:   Delirium;   Anesthesia
Interventions:   Procedure: Subarachnoid block;   Procedure: Spinal morphine
Sponsor:   AC Camargo Cancer Center
Completed

Thu, 28 Jun 2018 12:00:00 EDT

Efficacy of Convulsive Therapies for Bipolar Depression

Conditions:   Bipolar Disorder;   Bipolar Depression;   Bipolar I Disorder;   Bipolar II Disorder
Interventions:   Device: Magnetic Seizure Therapy (MST);   Device: Electroconvulsive Therapy (ECT)
Sponsors:   Centre for Addiction and Mental Health;   University of British Columbia;   Ontario Shores Centre for Mental Health Sciences;   Brain Canada
Recruiting

Wed, 22 Aug 2018 12:00:00 EDT

A Relation of Morphine-induced Itch and Pain Processing

Conditions:   Morphine;   Itch
Interventions:   Drug: Morphine;   Drug: Placebo oral tablet;   Drug: Histamine;   Drug: Cowhage (Mucuna Pruriens);   Drug: isotonic saline
Sponsor:   Aalborg University
Completed

Fri, 04 Oct 2019 12:00:00 EDT

Electroacupuncture for Laparoscopic/ Robotic Colorectal Surgery

Condition:   Acute Pain
Interventions:   Device: electroacupuncture;   Drug: morphine
Sponsor:   The University of Hong Kong
Terminated

Mon, 16 May 2016 12:00:00 EDT

Palliation of Dyspnea in Advanced Chronic Obstructive Pulmonary Disease (COPD)

Condition:   Chronic Obstructive Pulmonary Disease (COPD)
Intervention:   Drug: Opioid (morphine sulphate) in low dose
Sponsors:   Nova Scotia Health Authority;   Canadian Institutes of Health Research (CIHR);   Nova Scotia Health Research Foundation;   Atlantic Health Sciences Corporation
Completed

Wed, 23 Sep 2009 12:00:00 EDT

The Optimization of Procedural Pain Control in Intensive Care Unit (ICU) Patients

Condition:   Critical Illness
Intervention:   Drug: morphine
Sponsors:   St. Antonius Hospital;   Erasmus Medical Center
Completed

Wed, 14 Nov 2007 12:00:00 EST

SEQ Block for Perioperative Analgesia in Acetabular Surgery

Conditions:   Anesthesia, Local;   Nerve Pain;   Pain, Postoperative;   Acetabular Fracture
Interventions:   Procedure: Single puncture combined lumbar erector spinae plane block and quadrates lumborum block;   Drug: Morphine Sulfate
Sponsor:   Alexandria University
Not yet recruiting

Wed, 30 Dec 2020 12:00:00 EST

RCT Comparing Analgesia Post-VATS With Epimorph VS Placebo

Conditions:   Thoracic Surgery, Video-assisted;   Postoperative Pain;   Rachianesthesia;   Sufentanil;   Morphine
Interventions:   Drug: Intrathecal Morphine/Sufentanil;   Device: PCA
Sponsor:   Université de Sherbrooke
Terminated

Mon, 02 Jun 2014 12:00:00 EDT

MORphine Use in the Fascia Iliaca Compartment Block With UltraSound

Conditions:   Humans;   Anesthetics, Local;   Morphine;   Pain Management;   Analgesia;   Pain;   Anesthesia, Local;   Fascia;   Emergency Medicine;   Analgesia, Patient-Controlled;   Ultrasonography;   Femoral Fracture
Interventions:   Drug: Levobupivacaine;   Drug: Placebo;   Drug: Acetaminophen;   Drug: Morphine;   Procedure: Fascia Iliaca Compartment Block with Levobupivacaine;   Procedure: Fascia Iliaca Compartment Block with placebo
Sponsors:   Zuyderland Medisch Centrum;   Fresenius Kabi
Terminated

Tue, 19 Feb 2019 12:00:00 EST

NAS Treatment - Opiate Versus Non-Opiate

Condition:   Neonatal Abstinence Syndrome
Interventions:   Drug: Morphine;   Drug: Clonidine
Sponsor:   Henrietta Bada
Completed

Tue, 27 Nov 2012 12:00:00 EST

Ropivacaine Continuous Wound Infusion Versus Intrathecal Morphine for Postoperative Analgesia After Cesarean Delivery

Condition:   Obstetric Pain
Interventions:   Device: wound infusion (Dosi-Pain® Kit, LEVENTON SAU, Spain);   Procedure: Spinal Anesthesia;   Drug: intrathecal morphine;   Drug: Ropivacaine (Ropivacaina Molteni®);   Drug: Normal saline
Sponsors:   Saint-Joseph University;   LEVENTON
Completed

Thu, 19 Apr 2018 12:00:00 EDT

Inhaled Morphine Compared With Morphine By Mouth in Treating Cancer Patients With Breakthrough Pain

Conditions:   Pain;   Unspecified Adult Solid Tumor, Protocol Specific
Interventions:   Drug: morphine sulfate;   Procedure: quality-of-life assessment
Sponsor:   Dana-Farber Cancer Institute
Completed

Fri, 27 Feb 2004 12:00:00 EST

Study Comparing a Nerve Block With Spinal Opiate to Provide Pain Relief for Hip Replacement Surgery

Condition:   Analgesia
Interventions:   Procedure: ultrasound guided fascia iliaca block;   Procedure: spinal morphine
Sponsors:   Rachel Kearns;   NHS Greater Glasgow and Clyde
Completed

Fri, 08 Oct 2010 12:00:00 EDT

Influence of Opioid Analgesia on Circulating Tumor Cells in Laparoscopic Colorectal Cancer Surgery

Conditions:   Colorectal Cancer;   Circulating Tumor Cell
Interventions:   Drug: Morphine;   Drug: Piritramid
Sponsors:   The Institute of Molecular and Translational Medicine, Czech Republic;   General University Hospital, Prague;   Tomas Bata Hospital, Czech Republic;   University Hospital Ostrava;   Hospital Novy Jicin
Recruiting

Tue, 09 Oct 2018 12:00:00 EDT

Ultrasound Guided Anterior Quadratus Lumborum Block

Conditions:   Postoperative Pain;   Ultrasound
Interventions:   Drug: Morphine Sulfate;   Procedure: Group P;   Procedure: Group A
Sponsor:   Bursa Yüksek İhtisas Education and Research Hospital
Completed

Wed, 07 Feb 2018 12:00:00 EST

Drug Drug Interactions of Aspirin and P2Y12-inhibitors

Conditions:   Drug Interaction Potentiation;   Myocardial Infarction
Interventions:   Drug: Morphine;   Drug: Placebo
Sponsor:   Medical University of Vienna
Completed

Wed, 08 Jun 2011 12:00:00 EDT

Multimodal Analgesia With Interfascial Continuous Wound Infiltration: A Randomized Clinical Trial

Condition:   Pain
Interventions:   Device: 19Gx500-mm Pajunk InfiltraLong® catheter;   Drug: morphine
Sponsor:   Hospital Galdakao-Usansolo
Completed

Fri, 22 Aug 2014 12:00:00 EDT

Ketorolac for Moderate to Severe Abdominal Pain in Children

Conditions:   Abdominal Pain;   Appendicitis;   Analgesia;   Child, Only;   Emergencies
Interventions:   Drug: Ketorolac Tromethamine 10 MG/ML;   Drug: Morphine Sulfate 10Mg/1mL Injection
Sponsor:   Hamilton Health Sciences Corporation
Recruiting

Thu, 27 Aug 2020 12:00:00 EDT

A Comparison of the Safety and Effectiveness of Two Forms of Patient-controlled Pain Medication Used After Scheduled Abdominal or Pelvic Surgery: The Fentanyl Transdermal System Versus the Morphine Intravenous Pump

Condition:   Pain, Postoperative
Intervention:   Drug: E-TRANS Fentanyl hydrochloride; Morphine
Sponsors:   Alza Corporation, DE, USA;   PriCara, Unit of Ortho-McNeil, Inc.
Completed

Mon, 19 Dec 2005 12:00:00 EST

A Comparison of the Safety and Effectiveness of Two Forms of Patient-controlled Pain Medication Used After Total Hip Replacement: The E-TRANS Fentanyl Transdermal System Versus the Morphine Intravenous Pump

Conditions:   Pain, Postoperative;   Analgesia
Intervention:   Drug: E-TRANS Fentanyl hydrochloride; Morphine
Sponsors:   Alza Corporation, DE, USA;   PriCara, Unit of Ortho-McNeil, Inc.
Completed

Tue, 13 Dec 2005 12:00:00 EST

Individualized Analgesia for Pediatric Adenotonsillectomy

Conditions:   Adenotonsillectomy;   Analgesia
Interventions:   Drug: Individualized oral morphine;   Drug: Conventional oral morphine
Sponsor:   Children's Hospital of Fudan University
Not yet recruiting

Wed, 26 Aug 2020 12:00:00 EDT

Morphine After Radiofrequency Ablation of Painful Bone Metastases in Patients With Cancer

Conditions:   Metastatic Cancer;   Pain;   Unspecified Adult Solid Tumor, Protocol Specific
Interventions:   Drug: Acetaminophen;   Drug: Morphine Sulfate;   Other: Questionnaire administration;   Procedure: Quality-of-life assessment;   Procedure: Radiofrequency ablation
Sponsor:   Institut Bergonié
Completed

Thu, 10 Jul 2008 12:00:00 EDT

Comparing the Outcome of Two Intraoperative Analgesia Techniques After Hepato-pancreato-biliary Surgery

Conditions:   Pain;   Analgesia;   Sedation
Interventions:   Drug: Intrathecal morphine;   Drug: Continuous IV remifentanil
Sponsor:   Tel-Aviv Sourasky Medical Center
Unknown status

Tue, 14 Sep 2010 12:00:00 EDT

Methadone, Morphine, or Oxycodone in Treating Pain in Patients With Cancer

Conditions:   Brain and Central Nervous System Tumors;   Chronic Myeloproliferative Disorders;   Leukemia;   Lymphoma;   Lymphoproliferative Disorder;   Multiple Myeloma and Plasma Cell Neoplasm;   Myelodysplastic Syndromes;   Myelodysplastic/Myeloproliferative Neoplasms;   Pain;   Precancerous Condition;   Unspecified Adult Solid Tumor, Protocol Specific
Interventions:   Drug: methadone hydrochloride;   Drug: morphine sulfate;   Drug: oxycodone hydrochloride
Sponsors:   M.D. Anderson Cancer Center;   National Cancer Institute (NCI)
Terminated

Fri, 01 Aug 2008 12:00:00 EDT

A Comparative Study With Parenteral Oxycodone, Morphine and Dexamethasone in Postoperative Pain in Paediatric Patients

Condition:   Post Tonsillectomy Pain
Interventions:   Drug: 0,1 mg/kg of oxycodone;   Drug: Morphine 0,1 mg/kg;   Drug: Dexamethasone 0,5 mg/kg;   Drug: NaCl 0,9%
Sponsor:   University of Turku
Unknown status

Tue, 12 Aug 2008 12:00:00 EDT

A Safety and Efficacy Study of Oral Tapentadol Extended-Release in Japanese Participants

Condition:   Neoplasms
Interventions:   Drug: Tapentadol ER;   Drug: Morphine SR
Sponsor:   Janssen Pharmaceutical K.K.
Completed

Mon, 07 Mar 2011 12:00:00 EST

Ketamine Improves Post-Thoracotomy Analgesia

Condition:   Post Operative Pain
Interventions:   Drug: morphine;   Drug: morphine ketamine
Sponsor:   Tel-Aviv Sourasky Medical Center
Completed

Fri, 29 Feb 2008 12:00:00 EST

Inhaled vs IV Opioid Dosing for the Initial Treatment of Severe Acute Pain in the Emergency Department

Conditions:   Pain, Acute;   Emergencies;   Morphine
Interventions:   Drug: inhaled titration of morphine chlorhydrate;   Drug: IV placebo;   Device: Inhaled placebo;   Drug: IV titration of morphine chlorhydrate
Sponsor:   University Hospital, Rouen
Unknown status

Tue, 22 Aug 2017 12:00:00 EDT

Hormone Function in Men Treated for Pain With Opioids or Placebo

Conditions:   Chronic Pain;   Osteoarthritis
Interventions:   Drug: MS Contin;   Drug: Placebo
Sponsor:   National Institute of Nursing Research (NINR)
Completed

Wed, 20 Aug 2008 12:00:00 EDT

Oxycodone Hydrochloride Injection in the Postoperative Pain Relieving Treatment

Condition:   Other Acute Postoperative Pain
Interventions:   Drug: Oxycodone;   Drug: Morphine
Sponsor:   Mundipharma (China) Pharmaceutical Co. Ltd
Completed

Fri, 25 Feb 2011 12:00:00 EST

Cyclizine Vs. Dexamethasone for Nausea and Vomiting Following Intrathecal Morphine in Cases of Cesarean Section

Condition:   Spinal Anesthetics Causing Adverse Effects in Therapeutic Use
Intervention:   Drug: IV Cyclizine versus IV Dexamethasone for prevention of nausea and vomiting after intrathecal morphine in patients undergoing cesarean section
Sponsor:   Assiut University
Unknown status

Tue, 30 Apr 2019 12:00:00 EDT

Analgesic Efficacy of Transmucosal Fentanyl for Breakthrough Pain Caused by Interventional Gastrostomy

Conditions:   Gastrostomy;   Breakthrough Pain;   Upper Aerodigestive Tract Neoplasms
Interventions:   Drug: Fentanyl;   Drug: Morphine Sulfate;   Drug: Fentanyl placebo;   Drug: Morphine Sulfate placebo;   Procedure: Gastrostomy
Sponsor:   Central Hospital, Nancy, France
Completed

Tue, 16 Aug 2016 12:00:00 EDT

Psychological Intervention and Physiotherapy With Medication Improves CRPS Patients Outcome

Condition:   CRPS
Interventions:   Drug: Morphine, memantine;   Behavioral: Psychological intervention;   Other: Physiotherapy intervention
Sponsor:   Helsinki University Central Hospital
Completed

Wed, 10 Jun 2015 12:00:00 EDT

Pharmacokinetics and Pharmacodynamics of TRV130, Morphine, and Placebo in Healthy Subjects

Condition:   Pain, Acute
Interventions:   Drug: TRV130 1.5 mg;   Drug: TRV130 3 mg;   Drug: TRV130 4.5 mg;   Drug: Morphine 10 mg;   Drug: Placebo
Sponsor:   Trevena Inc.
Completed

Tue, 11 Mar 2014 12:00:00 EDT

IV Paracetamol, Dexketoprofen or Morphine for the Treatment of Low Back Pain

Condition:   Low Back Pain
Interventions:   Drug: paracetamol;   Drug: morphine;   Drug: Dexketoprofen;   Drug: Paracetamole
Sponsor:   Pamukkale University
Completed

Tue, 23 Aug 2011 12:00:00 EDT

Naloxone for the Treatment of Opioid-Induced Pruritus

Condition:   Pruritus
Interventions:   Drug: Naloxone;   Drug: Saline/Morphine
Sponsor:   University of British Columbia
Completed

Thu, 18 Feb 2010 12:00:00 EST

Analgesic and Antihyperalgesic Effects of Morphine and Buprenorphine

Condition:   Pain
Interventions:   Drug: morphine LO;   Drug: Morphine Hi;   Drug: Buprenorphine LO;   Drug: Buprenorphine Hi;   Other: saline
Sponsors:   mads u werner;   Norpharma A/S
Completed

Tue, 15 Feb 2011 12:00:00 EST

Evaluation of MST-188 in Acute Lower Limb Ischemia

Condition:   Acute Limb Ischemia
Interventions:   Drug: MST-188;   Drug: Saline
Sponsor:   Mast Therapeutics, Inc.
Terminated

Fri, 21 Mar 2014 12:00:00 EDT

Drug Interactions Between Morphine and Orally or IV Administered Acetaminophen

Condition:   Pain
Interventions:   Drug: Oral Acetaminophen;   Drug: IV Acetaminophen;   Drug: IV Morphine;   Drug: Placebo Tablets;   Drug: Saline
Sponsor:   Mallinckrodt
Completed

Thu, 28 Jul 2016 12:00:00 EDT

Intravenous vs Oral Analgesia in Cancer Patients With Severe Pain After Successful Titration

Condition:   Cancer Pain
Interventions:   Drug: PCA IV Hydromorphone (continuous dose = 0);   Drug: PCA IV Hydromorphone (continuous dose ≠ 0);   Drug: Oral morphine
Sponsor:   Fujian Cancer Hospital
Completed

Tue, 28 Jan 2020 12:00:00 EST

Femoral Neuropathy After Anterior Cruciate Ligament Reconstruction: Femoral Nerve Block vs Patient-controlled Analgesia (PCA)

Condition:   Femoral Neuropathy
Interventions:   Procedure: Femoral nerve block;   Procedure: PCA morphine
Sponsor:   Centre Hospitalier Universitaire Vaudois
Completed

Wed, 23 Mar 2011 12:00:00 EDT

Opiate-Induced Tolerance & Hyperalgesia in Pain Patients

Conditions:   Chronic Low Back Pain;   Opioid-induced Hyperalgesia
Interventions:   Drug: Morphine;   Drug: Placebo
Sponsor:   National Institute of General Medical Sciences (NIGMS)
Completed

Sun, 30 Oct 2005 12:00:00 EDT

Magnetic Seizure Therapy (MST) for Treatment Resistant Major Depression

Condition:   Major Depression
Interventions:   Device: Thymatron;   Device: Tonica MagPro MST
Sponsor:   University Hospital, Bonn
Completed

Fri, 10 Oct 2008 12:00:00 EDT

Adductor Canal Block Versus Patient Controlled Analgesia, in the Surgical Stress Response for Anterior Cruciate Ligament Repair

Conditions:   Anesthesia;   Stress, Physiological;   Surgery
Interventions:   Procedure: Adductor Canal Block;   Device: Morphine Patient Controlled Analgesia
Sponsor:   Pontificia Universidad Catolica de Chile
Withdrawn

Mon, 15 Mar 2021 12:00:00 EDT

The Analgesic Efficacy of Periarticular Infiltration of Local Anaesthetic for Total Hip Replacement

Condition:   Total Hip Arthroplasty
Interventions:   Drug: Levobupivacaine;   Drug: Intrathecal morphine
Sponsor:   Cork University Hospital
Unknown status

Thu, 10 Mar 2011 12:00:00 EST

Preemptive Analgesia With Morphine Sulphate in Major Urological Surgery

Condition:   Pain
Intervention:  
Sponsor:   University of Roma La Sapienza
Unknown status

Wed, 22 Jan 2014 12:00:00 EST

Choosing Opioid Management for Pain and Analyzing Acute Chest Syndrome (ACS) Rates Equally

Conditions:   Pain;   Sickle Cell Disease
Interventions:   Drug: Morphine;   Drug: Nubain
Sponsors:   Children's Healthcare of Atlanta;   Atlanta Clinical and Translational Science Institute
Completed

Mon, 27 Jun 2011 12:00:00 EDT

Buprenorphine in Acute Renal Colic Pain Management

Conditions:   Acute Pain Management;   Renal Colic
Interventions:   Drug: Buprenorphine;   Drug: Morphine
Sponsor:   Tehran University of Medical Sciences
Completed

Wed, 07 Mar 2012 12:00:00 EST

Interest of the Injection of Morphine, in Addition to a Local Anesthetic When Performing a Combined Spinal-epidural for Labor Analgesia

Condition:   Pregnant Women
Interventions:   Drug: experimental group : sequential combined spinal epidural with local anesthetic injection (chirocaine) associated with morphine (sufentanil).;   Drug: control group : sequential combined spinal epidural with local anesthetic injection (chirocaine) alone.
Sponsor:   CHU de Reims
Completed

Tue, 16 Aug 2016 12:00:00 EDT

To Compare the Efficacy and Patients' Satisfaction for the Treatment of Post Cesarean Pain of Two Protocols: Oral Medications in Fixed Time Interval Administration Versus Spinal Morphine

Condition:   Post Cesarean Pain Management
Interventions:   Drug: Tramadol hydrochloride;   Drug: Morphine;   Drug: Paracetamol;   Drug: Diclofenac;   Drug: TAB. Percocet (Oxycodone 5MG/Paracetamol 325 MG)
Sponsor:   HaEmek Medical Center, Israel
Completed

Tue, 12 May 2015 12:00:00 EDT

A Study of TRV130 for the Treatment of Pain After Bunionectomy

Condition:   Acute Pain
Interventions:   Drug: TRV130;   Drug: Morphine;   Drug: Placebo
Sponsor:   Trevena Inc.
Completed

Tue, 01 Apr 2014 12:00:00 EDT

Clinical Effectiveness and Safety of Intraoperative Methadone in Patients Undergoing Laparoscopic Hysterectomy

Condition:   Postoperative Pain
Interventions:   Drug: Methadone;   Drug: Morphine
Sponsor:   University of Aarhus
Recruiting

Tue, 09 Apr 2019 12:00:00 EDT

Ultrasound Guided Femoral Nerve Block

Condition:   Hip Fracture
Interventions:   Other: ultra-sound guide;   Drug: bupivacaine;   Drug: morphine
Sponsor:   Beth Israel Deaconess Medical Center
Recruiting

Fri, 06 Mar 2015 12:00:00 EST

Confirmatory Efficacy and Safety Trial of Magnetic Seizure Therapy for Depression

Conditions:   Depression;   Unipolar Depression;   Treatment Resistant Depression
Interventions:   Device: Magnetic Seizure Therapy;   Device: Electroconvulsive Therapy
Sponsors:   University of Texas Southwestern Medical Center;   National Institute of Mental Health (NIMH);   Centre for Addiction and Mental Health
Recruiting

Mon, 19 Jun 2017 12:00:00 EDT

Oral Self Medication Versus IV Administration of Pain Killers After Caesarian Delivery

Condition:   Caesarian Section
Interventions:   Drug: Acetaminophen, ketoprofen, morphine;   Drug: Acetaminophen, ketoprofen,morphine
Sponsors:   University Hospital, Montpellier;   Club anesthésie Reanimation Obstetricale
Completed

Thu, 29 Mar 2012 12:00:00 EDT

Platelet Inhibition After Pre-hospital Ticagrelor Using Fentanyl Compared to Morphine in Patients With ST-segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention

Condition:   Acute Myocardial Infarction
Interventions:   Drug: Fentanyl;   Drug: Morphine;   Drug: Ticagrelor;   Drug: Aspirin;   Drug: Unfractioned Heparin;   Procedure: Primary PCI
Sponsors:   Centre Hospitalier Universitaire Vaudois;   AstraZeneca
Completed

Mon, 24 Aug 2015 12:00:00 EDT

Study of Morphine in Postoperative Infants to Allow Normal Ventilation

Conditions:   Infant, Newborn, Diseases;   Pain
Intervention:   Drug: morphine
Sponsor:   Seattle Children's Hospital
Completed

Fri, 25 Feb 2000 12:00:00 EST

Evaluation of the Benefit of Non-opioid General Anaesthesia on Postoperative Pain in Laparoscopic Colonic Surgery

Condition:   Colectomy
Interventions:   Drug: anaesthesia without opiates;   Drug: anaesthesia with morphine
Sponsor:   GCS Ramsay Santé pour l'Enseignement et la Recherche
Recruiting

Wed, 01 Sep 2021 12:00:00 EDT

Prospective Effect of Intravenous Ketorolac on Opioid Use and Complications Following Cesarean Delivery

Condition:   Analgesia, Obstetrical
Interventions:   Drug: Ketorolac;   Drug: Epidural Morphine;   Drug: Hydromorphone
Sponsor:   University Hospitals Cleveland Medical Center
Unknown status

Tue, 28 Jul 2015 12:00:00 EDT

Impact of Dexamethasone Added to Intra-articular Morphine and Bupivacaine for Post-operative Analgesia After Knee Arthroscopy

Condition:   Anesthesia
Interventions:   Drug: group M;   Drug: group MD
Sponsor:   Ain Shams University
Completed

Wed, 10 Mar 2021 12:00:00 EST

Erector Spinae Plane Block Catheters and Intrathecal Morphine for Hepatic Resection

Conditions:   Hepatic Resection;   Acute Pain;   Anesthesia;   Anesthesia, Local
Interventions:   Drug: 0.2% ropivacaine local anesthetic continuous erector spinae plane block;   Drug: 0.2% ropivacaine local anesthetic superficially taped continuous erector spinae plane block;   Drug: Spinal Morphine
Sponsor:   University of California, San Diego
Recruiting

Mon, 19 Apr 2021 12:00:00 EDT

Morphine Postoperative Analgesia and Pharmacokinetic/Pharmacodynamic Modeling

Condition:   Cardiopulmonar Artery Bypass Grafting
Intervention:  
Sponsors:   University of Sao Paulo;   Fundação de Amparo à Pesquisa do Estado de São Paulo;   Conselho Nacional de Desenvolvimento Científico e Tecnológico
Completed

Tue, 27 Mar 2012 12:00:00 EDT

Dexmedetomidine Supplemented Analgesia and Long-term Survival After Cancer Surgery

Conditions:   Elderly;   Surgery;   Analgesia;   Dexmedetomidine;   Long-term Outcome
Interventions:   Drug: Dexmedetomidine supplemented morphine analgesia;   Drug: Morphine analgesia
Sponsors:   Peking University First Hospital;   Affiliated Hospital of Hebei University;   Qingdao Municipal Hospital;   The Second Affiliated Hospital of Air Force Medical University;   Beijing Chao Yang Hospital;   Beijing Shijitan Hospital, Capital Medical University;   Beijing Tsinghua Chang Gung Hospital;   Peking University International Hospital;   Beijing Ditan Hospital;   Guizhou Provincial People's Hospital;   The Third Xiangya Hospital of Central South University;   Shanxi Provincial Cancer Hospital;   Tianjin Hospital of ITCWM-Nankai Hospital;   Zhongda Hospital Southeast University
Recruiting

Fri, 06 Jan 2017 12:00:00 EST

Dexmedetomidine Supplemented Analgesia and Incidence of Postoperative Delirium

Conditions:   Elderly;   Surgery;   Analgesia;   Dexmedetomidine;   Complication, Postoperative;   Delirium
Interventions:   Drug: Dexmedetomidine supplemented morphine analgesia;   Drug: Morphine analgesia
Sponsors:   Peking University First Hospital;   Affiliated Hospital of Hebei University;   Qingdao Municipal Hospital;   The Second Affiliated Hospital of Air Force Medical University;   Beijing Chao Yang Hospital;   Beijing Shijitan Hospital, Capital Medical University;   Beijing Tsinghua Chang Gung Hospital;   Peking University International Hospital;   Beijing Ditan Hospital;   Guizhou Provincial People's Hospital;   The Third Xiangya Hospital of Central South University;   Shanxi Provincial Cancer Hospital;   Tianjin Hospital of ITCWM-Nankai Hospital;   Zhongda Hospital Southeast University
Recruiting

Fri, 06 Jan 2017 12:00:00 EST

Efficacy Methadone for Management Postoperative Pain After the Use of Anesthesia Intravenous in Laparoscopic Cholecystectomy

Condition:   Pain, Postoperative
Interventions:   Drug: Morphine;   Drug: Methadone;   Drug: TIVA
Sponsor:   Universidad de Valparaiso
Completed

Wed, 17 Apr 2013 12:00:00 EDT

Breathlessness Exertion and Morphine Sulphate

Conditions:   Chronic Obstructive Pulmonary Disease;   Dyspnea
Interventions:   Drug: Placebo;   Drug: Morphine Sulfate;   Drug: Plus laxative (Docusate with senna);   Drug: Plus placebo laxative;   Device: FitBit charge HR (Accelerometer)
Sponsor:   Flinders University
Completed

Mon, 28 Mar 2016 12:00:00 EDT

Pain Relief of Metoprolol Versus Metoprolol Plus Morphine in Acute Chest Pain

Condition:   Acute Coronary Syndromes
Interventions:   Drug: Metoprolol;   Drug: metoprolol plus morphine
Sponsors:   Sahlgrenska University Hospital, Sweden;   AstraZeneca
Completed

Fri, 18 Jul 2008 12:00:00 EDT

High Pain Intervention in Cesarean Sections

Condition:   Other Chronic Postoperative Pain
Interventions:   Drug: Duramorph 150;   Drug: Acetaminophen;   Drug: Duramorph 300
Sponsor:   Wake Forest University Health Sciences
Completed

Fri, 18 Feb 2011 12:00:00 EST

Evaluation of the Safety and Efficacy of EXPAREL When Administered Into the TAP in Subjects Undergoing Cesarean Section

Condition:   Pain
Interventions:   Drug: Intrathecal morphine injection;   Drug: EXPAREL
Sponsor:   Pacira Pharmaceuticals, Inc
Terminated

Tue, 03 Feb 2015 12:00:00 EST

Efficacy of Nefopam and Morphine in Balanced Analgesia for Acute Ureteric Colic

Condition:   Renal Colic
Interventions:   Drug: Ketorolac and nefopam balanced analgesia;   Drug: Balanced analgesia using ketorolac and morphine;   Drug: Pain control with single analgesics (ketorolac)
Sponsors:   Seoul National University Hospital;   Pharmbio Korea
Unknown status

Fri, 02 Mar 2012 12:00:00 EST

Sub-dissociative Ketamine for the Management of Acute Pediatric Pain

Condition:   Pain
Interventions:   Drug: Ketamine;   Drug: Morphine
Sponsor:   HealthPartners Institute
Completed

Fri, 27 Sep 2013 12:00:00 EDT

Bunionectomy Trial With GRT6005

Condition:   Post Operative Pain
Interventions:   Drug: GRT6005;   Drug: Morphine;   Drug: Placebo
Sponsor:   Tris Pharma, Inc.
Completed

Tue, 31 Mar 2009 12:00:00 EDT

Comparative Effectiveness Clinical Trial of MST Compared to ECT in Major Depressive Disorder

Condition:   Major Depressive Disorder
Interventions:   Device: Electroconvulsive Therapy (n=30);   Device: Magnetic Seizure Therapy (n=30)
Sponsors:   Tanta University;   Nagy A. Youssef (Consultant on the MST technique)
Completed

Thu, 02 Jan 2020 12:00:00 EST

Reduction in Pain Intensity Following IV or Oral Pain-relieving Products

Condition:   Pain
Interventions:   Drug: IV Acetaminophen (Treatment A);   Drug: Oral Acetaminophen (Treatment B);   Drug: Placebo (Treatment C);   Other: Morphine (Treatment D)
Sponsor:   Mallinckrodt
Completed

Tue, 09 Feb 2016 12:00:00 EST

A Study of TRV130 for the Treatment of Pain After Abdominoplasty

Condition:   Pain
Interventions:   Drug: TRV130;   Drug: Morphine;   Drug: Placebo
Sponsors:   Trevena Inc.;   Lotus Clinical Research, LLC
Completed

Fri, 09 Jan 2015 12:00:00 EST

Oral Analgesic Utilization for CHildhood Musculoskeletal Injuries

Condition:   Musculoskeletal Injury
Interventions:   Drug: oral morphine and oral ibuprofen;   Drug: Oral morphine;   Drug: Oral ibuprofen
Sponsor:   St. Justine's Hospital
Completed

Mon, 17 Feb 2014 12:00:00 EST

Methadone in Neuropathic Pain

Condition:   Chronic Neuropathic Pain
Interventions:   Drug: Methadone;   Drug: Controlled Release Morphine
Sponsors:   Nova Scotia Health Authority;   Canadian Institutes of Health Research (CIHR);   Nova Scotia Health Research Foundation;   Dalhousie University
Terminated

Mon, 20 Sep 2010 12:00:00 EDT

Non-opioid Analgesic Combination With Morphine for Postoperative Analgesia.

Condition:   Post Operative Analgesia
Interventions:   Drug: Paracetamol;   Drug: Nefopam;   Drug: Ketoprofen;   Drug: Morphine
Sponsor:   Rennes University Hospital
Terminated

Thu, 20 Jun 2013 12:00:00 EDT

Genetic Effects on Dopamine Response to an Opiate

Conditions:   Polymorphism-Genetic;   Pain;   Addiction
Interventions:   Drug: Morphine;   Drug: Placebo
Sponsors:   National Institute on Alcohol Abuse and Alcoholism (NIAAA);   National Institute on Drug Abuse (NIDA)
Completed

Fri, 14 Jun 2013 12:00:00 EDT

Perioperative Pain Management In Spine Surgery Patients: Part I

Condition:   Pain
Interventions:   Drug: 150% Oral Morphine Equivalent (OME);   Other: Clinical Judgment
Sponsor:   Allina Health System
Completed

Thu, 06 Oct 2011 12:00:00 EDT

CHF6563 in Babies With Neonatal Opioid Withdrawal Syndrome

Condition:   Neonatal Opioid Withdrawal Syndrome
Interventions:   Drug: CHF6563;   Drug: Morphine;   Drug: CHF6563 matched placebo;   Drug: Morphine matched placebo
Sponsor:   Chiesi Farmaceutici S.p.A.
Recruiting

Thu, 26 Sep 2019 12:00:00 EDT

Premedication and Haemodynamics After Spinal Anesthesia

Condition:   Hemodynamics After Spinal Anesthesia
Interventions:   Drug: Morphine hydrochloride; Midazolam;   Drug: Midazolam
Sponsor:   Medical University of Gdansk
Completed

Wed, 10 Feb 2010 12:00:00 EST

Methadone for Spinal Fusion Surgery.

Conditions:   Pain, Postoperative;   Back Pain;   Opioid Use;   Methadone;   Degenerative Spondylolisthesis;   Stenosis, Spinal
Interventions:   Drug: Methadone;   Drug: Morphine
Sponsor:   Aarhus University Hospital
Recruiting

Sun, 21 Feb 2021 12:00:00 EST

Low Dose Extended-release Epidural and Lumbar Plexus Block Compared to Lumbar Plexus Block for Total Hip Resurfacing

Condition:   Hip Arthroplasty
Interventions:   Drug: Extended Release Epidural Morphine (EREM);   Drug: Placebo
Sponsors:   Wake Forest University;   EKR Therapeutics, Inc
Terminated

Wed, 08 Jul 2009 12:00:00 EDT

Opioid Treatment for Chronic Low Back Pain and the Impact of Mood Symptoms

Conditions:   Chronic Low Back Pain;   Degenerative Disc Disease;   Depression;   Anxiety
Interventions:   Drug: Oxycodone;   Drug: Morphine;   Drug: Placebo
Sponsors:   Brigham and Women's Hospital;   Arthritis Foundation;   National Institute on Drug Abuse (NIDA)
Completed

Mon, 02 Jan 2012 12:00:00 EST

The Effects of Scalp Block on Haemodynamic Response and Postoperative Pain in Posterior Fossa Surgery

Condition:   Posterior Fossa Tumors
Interventions:   Drug: Bupivacaine;   Drug: morphine patient controlled analgesia
Sponsor:   Istanbul University
Completed

Tue, 02 Aug 2016 12:00:00 EDT

A Study of Serial Magnetic Resonance Cholangiopancreatography (MRCP) Following Morphine-neostigmine and Secretin Provocation in Healthy Volunteers

Condition:   Sphincter of Oddi Dysfunction
Interventions:   Drug: Morphine;   Drug: Neostigmine;   Drug: 0.9% saline;   Drug: Secretin
Sponsor:   University of Nottingham
Completed

Wed, 02 Jun 2010 12:00:00 EDT

Effect of Pain Control on the Diagnosis of Acute Appendicitis on the Diagnostic Accuracy of General Surgeon

Condition:   Appendicitis
Intervention:   Drug: Morphine
Sponsor:   Seoul National University Hospital
Completed

Fri, 31 Oct 2008 12:00:00 EDT

Effects of Different Types of Perioperative Analgesia on Minimal Residual Disease Development After Colon Cancer Surgery

Conditions:   Colon Cancer;   Minimal Residual Disease
Interventions:   Other: Epidural analgesia;   Drug: Piritramide;   Drug: Morphine
Sponsors:   The Institute of Molecular and Translational Medicine, Czech Republic;   Brno University Hospital;   Tomas Bata Hospital, Czech Republic
Completed

Thu, 11 Dec 2014 12:00:00 EST

Brain Effects of Opiate Agonist and Antagonist

Condition:   Chronic Low-back Pain
Intervention:   Drug: Morphine
Sponsor:   University of Rochester
Completed

Fri, 10 Apr 2020 12:00:00 EDT

A Study of the Safety and Efficacy of Combination Therapy With Morphine, Phenylephrine and Sorbitol in Human Subjects

Condition:   Acute Pain
Interventions:   Drug: Morphine;   Drug: Sorbitol+Phenylephrine;   Drug: Sorbitol+Phenylephrine+Morphine;   Drug: Sorbitol low concentration+Phenylephrine+Morphine
Sponsor:   BioLineRx, Ltd.
Completed

Tue, 12 Sep 2006 12:00:00 EDT

Efficacy and Safety of EXPAREL Versus Standard of Care (SoC) in Subjects Undergoing Elective Cesarean Section

Conditions:   Elective Cesarean Section;   Pain Management
Interventions:   Drug: 50 mcg Duramorph+ EXPAREL + multi-modal pain regimen;   Drug: 150 mcg Duramorph + multi-modal pain regimen;   Drug: Exparel TAP + multi-modal pain regimen
Sponsor:   Pacira Pharmaceuticals, Inc
Completed

Tue, 26 Feb 2019 12:00:00 EST

Study To Assess The Effect Of Gabapentin, Diphenhydramine And Morphine On Cold Pain In Healthy Male Volunteers

Condition:   Healthy
Interventions:   Drug: Gabapentin;   Drug: Diphenhydramine;   Drug: Morphine;   Drug: Placebo
Sponsor:   Pfizer
Completed

Fri, 07 May 2010 12:00:00 EDT

Mindfulness as Treatment of Sexological Problems

Conditions:   Sexual Dysfunction;   Sexual Dysfunctions, Psychological;   Sexual Dysfunctions, Physiological
Interventions:   Behavioral: Mindfulness in Sex Therapy and Intimate Relationships (MSIR);   Behavioral: Treatment-as-usual
Sponsors:   Mental Health Services in the Capital Region, Denmark;   Den Owesenske Fond
Active, not recruiting

Thu, 13 Dec 2018 12:00:00 EST

Efficacy Study of Rectus Sheath Block to Control Postoperative Pain

Condition:   Pain, Postoperative
Interventions:   Procedure: ultrasound guided rectus sheath block;   Drug: Morphine
Sponsor:   Cukurova University
Completed

Tue, 15 Apr 2014 12:00:00 EDT

Evaluation of Repeat Administration of Purified Poloxamer 188

Condition:   Sickle Cell Disease
Intervention:   Drug: MST-188
Sponsor:   Mast Therapeutics, Inc.
Completed

Wed, 20 May 2015 12:00:00 EDT

Efficacy Study of Different Analgesic Options in Kidney Stone Pain Management

Conditions:   Renal Colic;   Urinary Calculi
Interventions:   Drug: Diclofenac;   Drug: Morphine;   Drug: Paracetamol;   Drug: Placebos
Sponsor:   Hamad Medical Corporation
Completed

Fri, 11 Jul 2014 12:00:00 EDT

Evaluation of Purified Poloxamer 188 in Vaso-Occlusive Crisis of Sickle Cell Disease (EPIC)

Conditions:   Vaso-occlusive Crisis;   Sickle Cell Disease
Interventions:   Drug: Saline;   Drug: MST-188
Sponsor:   Mast Therapeutics, Inc.
Completed

Fri, 30 Nov 2012 12:00:00 EST

Cortical Modulation of Acute Post-thoracotomy Pain With Transcranial Direct Current Stimulation

Condition:   Pain, Postoperative
Interventions:   Device: Transcranial direct current stimulation;   Drug: Morphine
Sponsor:   Military Medical Academy, Belgrade, Serbia
Completed

Thu, 29 Dec 2016 12:00:00 EST

Transversus Abdominis Plane Block for Laparoscopic Hysterectomy

Conditions:   Hysterectomy;   Laparoscopic Surgery
Interventions:   Other: USguided bilateral TAP block;   Drug: Morphine Patient Controlled Analgesia
Sponsor:   Istituti Ospitalieri di Cremona
Completed

Tue, 13 Mar 2012 12:00:00 EDT

Multicenter Study to Compare Intravenous and Oral Acetaminophen for the Treatment of Acute Moderate to Severe Pain

Condition:   Acute Pain, Postoperative
Interventions:   Drug: IV acetaminophen;   Drug: Oral acetaminophen;   Drug: Morphine
Sponsor:   Mallinckrodt
Terminated

Thu, 21 Apr 2016 12:00:00 EDT

Sensorial and Physiological Mechanism-based Assessments of Perioperative Pain

Condition:   Scoliosis
Interventions:   Drug: Clonidine;   Other: Morphine
Sponsor:   Dr. Jean A. Ouellet, MD, FRCSC
Suspended

Fri, 25 May 2018 12:00:00 EDT

Dexmedetomidine in Pediatric Tonsillectomy

Conditions:   Pediatric Adenotonsillectomy;   Post Operative Analgesia
Interventions:   Drug: Dexmedetomidine 0.75 mcg/kg;   Drug: Morphine 50 mcg/kg;   Drug: Morphine 100 mcg/kg;   Drug: Dexmedetomidine 1 mcg/kg
Sponsor:   Baylor College of Medicine
Completed

Wed, 27 Jan 2010 12:00:00 EST

Comparison of the Efficacy and Safety of Q8003 Versus Its Individual Components in Bunionectomy Patients

Condition:   Moderate to Severe Postoperative Pain
Interventions:   Drug: Q8003;   Drug: Morphine sulfate;   Drug: Oxycodone HCl
Sponsor:   QRxPharma Inc.
Completed

Fri, 20 Nov 2009 12:00:00 EST

Study Comparing Magnetic Seizure Therapy (MST) to Electroconvulsive Therapy (ECT) for Depression in Older Adults

Conditions:   Depression;   Major Depressive Episode;   Bipolar Disorder
Interventions:   Device: MagVenture MagPro MST;   Biological: RUL ECT
Sponsor:   New York State Psychiatric Institute
Completed

Wed, 05 Jun 2013 12:00:00 EDT

Postpartum Perineal Pain After Obstetric Anal Sphincter Injuries

Conditions:   Pain;   Postpartum Depression
Interventions:   Drug: Epidural saline + IV saline;   Drug: Epidural morphine 3 mg + IV saline;   Drug: Epidural morphine 3 mg + IV ketamine 0.3 mg/kg
Sponsor:   Northwestern University
Recruiting

Tue, 20 Mar 2018 12:00:00 EDT

Safety and Efficacy of Patient Controlled Analgesia in the Emergency Department

Condition:   Pain
Interventions:   Device: Patient-controlled analgesia;   Drug: morphine
Sponsors:   Albert Einstein College of Medicine;   National Institutes of Health (NIH);   National Institute of Nursing Research (NINR);   Jacobi Medical Center
Completed

Fri, 29 May 2009 12:00:00 EDT

Efficacy of Convulsive Therapies During Continuation

Conditions:   Depression;   Bipolar Depression;   Unipolar Depression;   Treatment Resistant Depression
Interventions:   Device: Magnetic Seizure Therapy (MST);   Device: RUL-UB ECT;   Device: Bitemporal ECT
Sponsors:   Centre for Addiction and Mental Health;   University of British Columbia;   Ontario Shores Centre for Mental Health Sciences;   Brain Canada
Recruiting

Thu, 18 Oct 2018 12:00:00 EDT

Pharmacogenomics Analysis of Morphine Pharmacokinetics in Pediatric Tonsillectomy and Adenoidectomy

Conditions:   Tonsillectomy;   Adenoidectomy;   Pharmacokinetics
Intervention:  
Sponsors:   Children's Hospital of Philadelphia;   Children's Anesthesiology Associates, Ltd.
Completed

Wed, 04 Feb 2009 12:00:00 EST

Gender and Opioid Consumption

Condition:   Postoperative; Parotitis
Intervention:   Drug: postoperative morphine
Sponsor:   Mansoura University
Unknown status

Fri, 30 Dec 2016 12:00:00 EST

Effects of Analgesia Methods on Vascular Endothelial Growth Factor* and Inflammatory Responses in Breast Cancer Surgery

Condition:   Breast Cancer
Interventions:   Drug: Morphine;   Procedure: Erector Spinae Block;   Drug: Control
Sponsor:   Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Not yet recruiting

Wed, 30 Dec 2020 12:00:00 EST

Opioid Effects on Swallowing Comparing Younger and Elderly Volunteers

Conditions:   Pharyngeal Dysfunction;   Pharyngeal Swallowing
Interventions:   Drug: Morphine;   Drug: Remifentanil
Sponsor:   Region Örebro County
Completed

Fri, 16 Aug 2013 12:00:00 EDT

The Influence of Postoperative Analgesia on Systemic Inflammatory Response and POCD After Femoral Fractures Surgery

Condition:   Postoperative Cognitive Dysfunction
Interventions:   Drug: morphine;   Drug: levobupivacaine
Sponsor:   Osijek University Hospital
Completed

Thu, 28 Jul 2016 12:00:00 EDT

Influence of METHoxyflurane on ANtiplatelet Effect of Ticagrelor in Patients With Unstable Angina Pectoris

Condition:   Unstable Angina
Interventions:   Drug: Ticagrelor followed with Methoxyflurane;   Drug: Ticagrelor followed with Morphine;   Drug: Ticagrelor alone
Sponsor:   Collegium Medicum w Bydgoszczy
Recruiting

Tue, 23 Jun 2020 12:00:00 EDT

A Study to Look at Tapentadol Tablets in Children and Adolescents in Pain

Condition:   Pain
Interventions:   Drug: Tapentadol prolonged release;   Drug: Morphine prolonged release
Sponsor:   Grünenthal GmbH
Completed

Fri, 30 May 2014 12:00:00 EDT

Does IVPCA Increase Opioid Consumption and Side Effects in Fast Track Orthopedic Procedures?

Condition:   Pain, Postoperative
Interventions:   Drug: Morphine as IVPCA;   Drug: Hydromorphone as IVPCA;   Drug: Morphine;   Drug: Hydromorphone
Sponsor:   Mount Sinai Hospital, Canada
Unknown status

Fri, 26 Aug 2016 12:00:00 EDT

A Randomized Control Trial Comparing Analgesic Benefits of Ultrasound-guided Single vs Continuous Quadratus Lumborum Blocks (QLB)vs Intrathecal Morphine(ITM) for Post Cesarean Section Pain

Condition:   Pain, Postoperative
Interventions:   Drug: Intrathecal morphine sulfate (ITM);   Drug: Bupivacaine hydrochloride;   Drug: ropivacaine hydrochloride
Sponsor:   The University of Texas Health Science Center, Houston
Active, not recruiting

Wed, 29 Apr 2020 12:00:00 EDT

Inhaled Cannabinoids Versus Immediate-release Oral Opioids for the Management of Breakthrough Cancer Pain

Conditions:   Cancer;   Breakthrough Cancer Pain
Interventions:   Drug: PPP001;   Drug: Morphine sulfate or Hydromorphone or Oxycodone
Sponsors:   Tetra Bio-Pharma;   Cognitive Research Corporation
Recruiting

Thu, 21 Jun 2018 12:00:00 EDT

Observational Prospective Study of Opiate-free Anesthesia for Anterior Total Hip Replacement

Conditions:   Rehabilitation;   Analgesia;   Anesthesia
Intervention:   Drug: Cumulative morphine consumption
Sponsor:   Hôpital Privé Sévigné
Completed

Wed, 02 Oct 2019 12:00:00 EDT

Perioperative Methadone Use to Decrease Opioid Requirement in Pediatric Spinal Fusion Patients

Conditions:   Scoliosis;   Pain
Interventions:   Drug: Methadone;   Other: Normal Saline;   Drug: Morphine
Sponsor:   Medical College of Wisconsin
Recruiting

Wed, 23 Sep 2015 12:00:00 EDT

Effect of Ramosetron in Prevention of Intrathecal Morphine Induced Nausea and Vomiting

Condition:   Postoperative Nausea and Vomiting
Interventions:   Drug: ramosetron;   Drug: Ondansetron
Sponsor:   Thammasat University
Completed

Wed, 13 Jul 2016 12:00:00 EDT

Duloxetine Potentiates the Analgesic Efficacy of Intrathecal Morphine

Condition:   Acute Pain
Interventions:   Drug: Duloxetine 60mg;   Drug: placebo
Sponsor:   Assiut University
Completed

Mon, 18 Jun 2018 12:00:00 EDT

Opioids for Refractory Breathlessness in Chronic Obstructive Pulmonary Disease

Conditions:   Chronic Obstructive Pulmonary Disease;   Dyspnea
Interventions:   Drug: Morphine sulfate;   Drug: Placebo
Sponsor:   Flinders University
Withdrawn

Wed, 27 May 2015 12:00:00 EDT

Dexmedetomidine Use in Infants Undergoing Cooling Due to Neonatal Encephalopathy (DICE Trial)

Conditions:   Hypoxic-Ischemic Encephalopathy;   Pain
Interventions:   Drug: Dexmedetomidine Hydrochloride;   Drug: Morphine Sulfate
Sponsor:   University of Utah
Not yet recruiting

Fri, 26 Feb 2021 12:00:00 EST

RCT Comparing the Analgesic Efficacy of 4 Therapeutic Strategies Based on 4 Different Major Opioids (Fentanyl, Oxycodone, Buprenorphine vs Morphine) in Cancer Patients With Moderate/Severe Pain, at the Moment of Starting 3rd Step of WHO Analgesic Ladder.

Conditions:   Cancer;   Cancer Pain
Interventions:   Drug: Morphine;   Drug: Fentanyl;   Drug: Buprenorphine;   Drug: Oxycodone
Sponsor:   Mario Negri Institute for Pharmacological Research
Completed

Tue, 12 Mar 2013 12:00:00 EDT

Palliative Morphine With or Without Concurrent Modafinil

Conditions:   Cancer;   Pain Palliation;   Excessive Sleepiness
Interventions:   Drug: Modafinil;   Drug: Placebo
Sponsor:   Dr. Rajendra Prasad Government Medical College
Unknown status

Fri, 11 Jan 2013 12:00:00 EST

Altered Drug Disposition and Biomarkers for Diagnosis of Chronic Inflammatory Liver Disease

Condition:   Fatty Liver
Interventions:   Other: High fat meal;   Drug: Morphine
Sponsors:   University of North Carolina, Chapel Hill;   University of North Carolina, Greensboro
Completed

Fri, 11 Jan 2013 12:00:00 EST

Multisystemic Therapy (MST) for Obesity in African American Youth

Condition:   Obesity
Interventions:   Behavioral: Multisystemic Therapy (MST);   Behavioral: Shapedown
Sponsors:   Wayne State University;   American Diabetes Association
Completed

Wed, 30 Jan 2008 12:00:00 EST

Sequential and Mixture Injection of Opioids and Hyperbaric Bupivacaine

Conditions:   Bupivacaine Adverse Reaction;   Regional Anesthesia Morbidity;   Cesarean Section Complications
Intervention:   Drug: Bupivacaine-fentanyl-Morphine.
Sponsor:   Assiut University
Completed

Wed, 27 May 2020 12:00:00 EDT

Hydrocodone/Acetaminophen for Acute Pain Following Bunionectomy

Condition:   Pain
Interventions:   Drug: Hydrocodone/Acetaminophen Extended Release;   Drug: Acetaminophen;   Drug: Morphine Extended Release;   Drug: Placebo
Sponsor:   AbbVie (prior sponsor, Abbott)
Completed

Thu, 24 Dec 2009 12:00:00 EST

Non-interventional Study to Assess Adherence to Treatment for Patients With RMS (MAIN-MS)

Condition:   Relapsing Multiple Sclerosis (RMS)
Intervention:   Drug: Rebif (Interferon beta-1a)
Sponsors:   Merck KGaA, Darmstadt, Germany;   Merck Serono Middle East FZ LLC
Completed

Fri, 30 Sep 2016 12:00:00 EDT

The Efficacy of Serratus Anterior Plane Block (ESAPB) for Thoracotomy: a Prospective Study

Conditions:   Pain, Postoperative;   Anesthesia;   Thoracotomy
Interventions:   Procedure: Serratus anterior plane block;   Drug: Intravenous patient-controlled-analgesia morphine
Sponsor:   Shanghai Zhongshan Hospital
Completed

Fri, 15 Feb 2019 12:00:00 EST

Comparison of Efficacy and Safety of the Postoperative Analgesia Methods

Condition:   Supratentorial Neoplasms
Interventions:   Drug: Morphine;   Drug: Dexketoprofen;   Drug: Placebo
Sponsor:   Istanbul University
Unknown status

Tue, 11 Oct 2016 12:00:00 EDT

The Analgesic Efficacy of Bilateral Erector Spinae Plane Block in Comparison With Intrathecal Morphine After Elective Cesarean Section

Condition:   Postoperative Pain
Intervention:   Procedure: Erector Spinae Plane Block
Sponsor:   Fayoum University
Completed

Thu, 02 May 2019 12:00:00 EDT

Impact of Dexmedetomidine on Sleep Quality

Conditions:   Elderly;   Surgery;   Analgesia;   Dexmedetomidine;   Complication,Postoperative;   Sleep Quality
Interventions:   Drug: Dexmedetomidine;   Drug: Placebo
Sponsor:   Peking University First Hospital
Completed

Tue, 18 Apr 2017 12:00:00 EDT

Ketamine for Acute Painful Crisis in Sickle Cell Disease Patients

Condition:   Sickle Cell Crisis
Interventions:   Drug: Morphine Group;   Drug: Ketamine Group;   Other: standard IV hydration
Sponsor:   Dammam University
Unknown status

Tue, 13 Feb 2018 12:00:00 EST

Thoracic Paravertebral Blocks in Open Nephrectomy

Conditions:   Nephrectomy;   Analgesia
Interventions:   Drug: Ropivacaine;   Drug: Morphine
Sponsors:   Asklepieion Voulas General Hospital;   Michail Tsagkaris;   Chryssoula Staikou;   Ioannis Karavokyros
Unknown status

Fri, 09 Feb 2018 12:00:00 EST

A Study to Compare Patient-controlled Pain Medications Delivered Either Through the Skin or Intravenously

Conditions:   Pain;   Analgesia, Patient-Controlled;   Pain, Postoperative
Interventions:   Drug: IONSYS (fentanyl HCl) Iontophoretic TransdermalSystem;   Drug: IV Morphine Patient-Controlled Analgesia (IV PCA)
Sponsors:   Janssen-Cilag International NV;   Alza Corporation, DE, USA
Completed

Fri, 16 Oct 2009 12:00:00 EDT

Dose Finding Study of STR-324

Condition:   Pain, Acute
Interventions:   Drug: Morphine;   Drug: Morphine HCl;   Drug: STR-324
Sponsor:   Alaxia SAS
Recruiting

Mon, 12 Oct 2020 12:00:00 EDT

Methadone Demonstration Project With Neonatal Intensive Care Unit Infants Diagnosed With Neonatal Abstinence Syndrome

Condition:   Neonatal Abstinence Syndrome
Interventions:   Drug: Methadone;   Drug: Morphine
Sponsors:   Johns Hopkins All Children's Hospital;   Florida Department of Health
Terminated

Mon, 01 May 2017 12:00:00 EDT

Efficacy of Sublingual Midazolam in Association With Oral Morphine in Children Analgesia After Bone Fracture

Condition:   Fractures
Interventions:   Drug: Midazolam;   Drug: Placebo
Sponsor:   Assistance Publique - Hôpitaux de Paris
Completed

Wed, 27 Dec 2006 12:00:00 EST

Intrathecal Morphine for Robotic-assisted Laparoscopic Hysterectomy.

Condition:   Opioid-Related Disorders
Intervention:   Procedure: Robotic-assisted hysterectomy
Sponsor:   Karlstad Central Hospital
Recruiting

Sat, 19 Dec 2020 12:00:00 EST

Impact of Morphine Treatment on Platelet Inhibition in Acute Myocardial Infarction

Condition:   Acute Myocardial Infarction
Interventions:   Drug: Morphinhydrochloricum;   Drug: Metoclopramide;   Drug: Ticagrelor;   Drug: Isotonic sodium chloride
Sponsor:   University of Luebeck
Completed

Fri, 11 Dec 2015 12:00:00 EST

Attention and Memory Disorders Related to Acute Morphine

Condition:   Memory Disorders
Intervention:   Other: Two tests evaluating memory and attention
Sponsor:   University Hospital, Toulouse
Unknown status

Wed, 25 Apr 2018 12:00:00 EDT

Efficacy and Safety Study of Nasalfent for Treatment of Breakthrough Cancer Pain in Patients Taking Regular Opioids

Condition:   Cancers, Pain
Interventions:   Drug: Fentanyl citrate;   Drug: Immediate release morphine sulphate
Sponsor:   Archimedes Development Ltd
Completed

Thu, 10 Jan 2008 12:00:00 EST

Serratus Intercostal Plane Block,New Analgesia in Supraumbilical Surgery

Conditions:   Postoperative Pain;   Analgesia;   Local Anaesthetic;   Abdominal Injury
Interventions:   Procedure: fascial block as postoperative analgesia;   Drug: Morphine;   Device: PCA CADD Smith Medical pumps
Sponsor:   Hospital Medina del Campo
Completed

Mon, 24 Feb 2020 12:00:00 EST

Effect of Thoracic Epidural Analgesia for Thoracotomy on the Occurrence of AF

Conditions:   Posterolateral Thoracotomy;   Lung Resection;   Thoracic Epidural Analgesia;   Sympathetic Outflow;   Atrial Fibrillation
Interventions:   Other: Thoracic Epidural Analgesia (TEA);   Other: TEA followed by Intravenous morphine
Sponsor:   Larissa University Hospital
Unknown status

Wed, 31 Oct 2012 12:00:00 EDT

U/S-guided Continuous Quadratus Lumborum Block III in Percutaneous Nephrolithotomy

Conditions:   Analgesia;   Surgery;   Renal Stone
Interventions:   Procedure: Continous Quadratum Lumborum Block III;   Procedure: Single dose Quadratum Lumborum Block III;   Procedure: Intra-venous Morphine
Sponsor:   Nazmy Edward Seif
Recruiting

Tue, 16 Mar 2021 12:00:00 EDT

Perioperative Analgesic Modalities for Breast Cancer Surgeries

Condition:   Analgesia
Interventions:   Procedure: serratus plane block;   Procedure: erector spinae block;   Drug: Morphine Sulfate
Sponsor:   National Cancer Institute, Egypt
Completed

Thu, 30 Jan 2020 12:00:00 EST

Reduced Opioid Analgesic Requirements Via Improved Endogenous Opioid Function

Condition:   Chronic Pain
Interventions:   Behavioral: 6 week aerobic exercise intervention;   Drug: Placebo;   Drug: Morphine;   Drug: naloxone
Sponsors:   Vanderbilt University Medical Center;   National Institute on Drug Abuse (NIDA)
Completed

Thu, 11 Jun 2015 12:00:00 EDT

Influence of Opioid Analgesia on Circulating Tumor Cells in Open Colorectal Cancer Surgery

Conditions:   Colorectal Cancer;   Circulating Tumor Cell
Interventions:   Drug: Morphine;   Drug: Piritramid;   Drug: Epidural
Sponsors:   The Institute of Molecular and Translational Medicine, Czech Republic;   General University Hospital, Prague;   Tomas Bata Hospital, Czech Republic;   University Hospital Ostrava;   Hospital Novy Jicin
Recruiting

Tue, 09 Oct 2018 12:00:00 EDT

Testing MST to Improve Adherence Among Youth With Chronic Poor Metabolic Control

Condition:   Type 1 Diabetes
Intervention:   Behavioral: Multisystemic Therapy
Sponsors:   Wayne State University;   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK);   Medical University of South Carolina
Completed

Thu, 23 Aug 2007 12:00:00 EDT

Adductor Canal Block and Recovery After Total Knee Replacement Surgery

Condition:   Total Knee Arthroplasty
Interventions:   Drug: Adductor Canal Block;   Drug: Adductor Canal Block with Morphine;   Drug: Local Infiltration
Sponsor:   University Health Network, Toronto
Completed

Wed, 08 Apr 2015 12:00:00 EDT

Ultrasound-assisted Bilateral Transversus Abdominis Plane Block for Open Prostatectomy

Conditions:   Prostatectomy;   Transversus Abdominis Plane Blockade;   Pain
Interventions:   Procedure: Transversus abdominis plane blockade;   Procedure: Morphine-patient-controlled-analgesia-device
Sponsor:   Charite University, Berlin, Germany
Completed

Thu, 21 Jun 2012 12:00:00 EDT

Magnetic Seizure Therapy (MST) for the Treatment of Major Depression

Condition:   Major Depressive Disorder
Interventions:   Device: Magstim Theta;   Device: Thymatron System IV
Sponsors:   Sarah Lisanby;   University of Texas;   Stanley Medical Research Institute
Completed

Wed, 09 Sep 2009 12:00:00 EDT

Morphine for the Treatment of Pain in Patients With Breast Cancer

Condition:   Pain
Interventions:   Drug: fentanyl citrate;   Drug: morphine sulfate
Sponsor:   Roswell Park Cancer Institute
Completed

Fri, 30 Jul 2004 12:00:00 EDT

Effectiveness of Bilateral Ultrasound-Guided Erector Spinae Plane Block

Condition:   Erector Spinae Plane Block
Interventions:   Drug: Bilateral Ultrasound-Guided Erector Spinae Plane Block;   Drug: Morphine Consumption
Sponsor:   Cairo University
Completed

Tue, 01 Oct 2019 12:00:00 EDT

Morphine-Midazolam in Pre-hospital Traumatic Patients With Severe Acute Pain

Condition:   Acute Traumatic Pain
Intervention:   Drug: Midazolam
Sponsors:   Centre Hospitalier de Cornouaille;   Ministry of Health, France
Completed

Wed, 21 Nov 2012 12:00:00 EST

The ReModel IHC Study for ESRD Patients

Condition:   Dialysis Access Malfunction
Intervention:   Device: Alio Medical Remote Monitoring System (RMS)
Sponsor:   Alio Medical
Not yet recruiting

Thu, 09 Sep 2021 12:00:00 EDT

Effects of General Anesthesia and Spinal-Morphine Anesthesia on Recovery and Comfort After Benign Abdominal Hysterectomy

Condition:   Hysterectomy (MeSH nr: E04.950.300.399)
Interventions:   Drug: Bupivacain;   Drug: Morphine;   Drug: Propofol;   Drug: Fentanyl;   Drug: Rocuronbromid
Sponsor:   Preben Kjolhede
Completed

Mon, 10 Sep 2007 12:00:00 EDT

Intrathecal Morphine Administration Using Implantable Pump With Continuous or Programmable Flow

Conditions:   Advanced Cancer;   Intractable Pain
Interventions:   Device: Implantable pump with continuous flow;   Device: Implantable pump with programmable flow.
Sponsor:   Institut Cancerologie de l'Ouest
Completed

Fri, 30 Mar 2012 12:00:00 EDT

Liposomal Bupivacaine in Total Knee Arthroplasty

Conditions:   Pain, Postoperative;   Arthroplasty, Replacement, Knee;   Osteoarthritis
Interventions:   Drug: Liposomal bupivacaine;   Drug: bupivacaine HCl, morphine, epinephrine, methylprednisolone
Sponsors:   Miller Orthopedic Specialists;   Creighton University Medical Center;   CHI Health Mercy Hospital
Withdrawn

Fri, 24 Apr 2015 12:00:00 EDT

Efficacy and Safety of Ultra-low Dose Methadone as Adjuvant Analgesic in Cancer Patients With Pain

Condition:   Pain, Intractable
Interventions:   Drug: oral methadone;   Drug: oral morphine
Sponsor:   McGill University Health Centre/Research Institute of the McGill University Health Centre
Unknown status

Mon, 22 Feb 2016 12:00:00 EST

Post-cesarean Pain Control Via Continuous Infusion of Ropivacain et Diclogenac Into the Wound Versus Intathecal Morphine

Condition:   Cesarean Section
Interventions:   Drug: Reference;   Drug: Experimental
Sponsor:   Centre Hospitalier Universitaire de Nīmes
Withdrawn

Wed, 29 Sep 2010 12:00:00 EDT

An Efficacy and Safety Study of Transdermal Therapeutic System (TTS)-Fentanyl in Thai Participants With Chronic Non-Malignant Pain

Condition:   Chronic Pain
Interventions:   Drug: TTS-Fentanyl;   Drug: Morphine
Sponsor:   Janssen-Cilag Ltd.,Thailand
Completed

Fri, 22 Mar 2013 12:00:00 EDT

A Comparison Trial Between PCA and Epidural Analgesia for Pectus Excavatum Repair

Condition:   Pectus Excavatum
Interventions:   Drug: Hydromorphone;   Drug: Morphine
Sponsor:   Baylor College of Medicine
Terminated

Wed, 05 Feb 2014 12:00:00 EST

Pain Treatment for Sciatica

Conditions:   Radiculopathy;   Sciatica
Interventions:   Drug: Nortriptyline;   Drug: Morphine
Sponsor:   National Institute of Dental and Craniofacial Research (NIDCR)
Completed

Mon, 05 Feb 2001 12:00:00 EST

Epidural vs. Wound Catheter Following Liver Resection

Condition:   Transplant Surgery
Intervention:   Procedure: This arm will received perioperative transversus abdominis plane (TAP) block followed by continuous infusion of local anaestheic by wound catheters and an IV morphine PCA.
Sponsor:   The Leeds Teaching Hospitals NHS Trust
Completed

Mon, 20 Aug 2018 12:00:00 EDT

A Health Economic Trial in Adult Patients Undergoing Laparoscopic Colectomy

Condition:   Bowel Obstruction
Interventions:   Drug: IV morphine sulfate or Sponsor-approved equivalent;   Drug: EXPAREL
Sponsors:   Pacira Pharmaceuticals, Inc;   Registrat-Mapi
Terminated

Mon, 10 Feb 2014 12:00:00 EST

Intravenous Acetaminophen and Morphine Versus Intravenous Morphine Alone for Acute Pain in the Emergency Department

Condition:   Pain Management
Interventions:   Drug: placebo of acetaminophen IV;   Drug: acetaminophen IV
Sponsor:   Nantes University Hospital
Recruiting

Fri, 01 Nov 2019 12:00:00 EDT

Methadone in Pediatric and Adult Sickle Cell Patients

Condition:   Sickle Cell Disease
Interventions:   Drug: Morphine;   Drug: Methadone
Sponsor:   Washington University School of Medicine
Completed

Fri, 26 Sep 2008 12:00:00 EDT

Comparison of Low-dose Epidural With Intravenous Narcotic Versus Intravenous Narcotic Alone

Condition:   Pain
Intervention:   Drug: Bupivacaine, Clonidine, Morphine
Sponsor:   University of North Carolina, Chapel Hill
Terminated

Mon, 06 Feb 2006 12:00:00 EST

Pregabalin, Celecoxib, Total Knee Arthroplasty and Intrathecal Morphine

Conditions:   Postoperative Pain Management;   Total Knee Arthroplasty
Interventions:   Drug: Pregabalin;   Drug: Celecoxib;   Drug: Pregabalin with celecoxib;   Drug: Placebo
Sponsors:   Chulalongkorn University;   Bhumibol Adulyadej Hospital;   King Chulalongkorn Memorial Hospital
Completed

Fri, 29 Apr 2011 12:00:00 EDT

Switching From Morphine to Methadone. A Clinical, Pharmacological and Pharmacogenetic Study

Condition:   Cancer
Intervention:   Drug: Methadone
Sponsor:   Norwegian University of Science and Technology
Completed

Fri, 16 Sep 2005 12:00:00 EDT

Transversus Abdominis Plane Block for Postoperative Analgesia in Living Donor Hepatectomy

Condition:   Acute Pain
Interventions:   Drug: Transversus Abdominis Plane Block;   Drug: standard general anesthesia
Sponsor:   Inonu University
Completed

Tue, 05 Jan 2016 12:00:00 EST

High Frequency Oscillatory Ventilation for Acute Respiratory Distress Syndrome (ARDS)

Condition:   Acute Respiratory Distress Syndrome
Interventions:   Device: Lung protective CMV;   Device: HFO-RMs
Sponsors:   University of Athens;   University of Thessaly
Terminated

Wed, 23 Nov 2011 12:00:00 EST

A Trial of SHR0410 Injection for the Treatment of Pain After Endoscopic Surgery of the Lower Abdominal

Condition:   Pain
Interventions:   Drug: SHR0410 Injection;   Drug: Placebo;   Drug: Morphine
Sponsor:   Jiangsu HengRui Medicine Co., Ltd.
Not yet recruiting

Wed, 21 Apr 2021 12:00:00 EDT

Efficacy of Caudal Block on Intra-operative Anal Sphincter Muscle Tone and Post-operative Analgesia During Anal Sphincter Sparing Procedures Under General Anaesthesia

Condition:   Efficacy of Caudal Block on Intra-operative Anal Sphincter Muscle Tone
Interventions:   Procedure: Caudal block;   Drug: Morphine
Sponsor:   Kasr El Aini Hospital
Not yet recruiting

Thu, 03 Dec 2020 12:00:00 EST

A Study to Evaluate Buprenorphine Transdermal Patch in Chinese Subjects With Moderate to Severe Chronic Cancer Pain

Condition:   Cancer Pain
Interventions:   Drug: Buprenorphine transdermal patches;   Drug: Morphine Sulfate Sustained-Release Tablet
Sponsor:   Mundipharma (China) Pharmaceutical Co. Ltd
Unknown status

Thu, 30 May 2019 12:00:00 EDT

Nasal Fentanyl And Renal Colic

Condition:   Acute Renal Colic
Interventions:   Drug: FENTANYL;   Drug: Ketorolac Tromethamine AND morphine
Sponsor:   Valduce Hospital
Completed

Wed, 20 Apr 2011 12:00:00 EDT

Comparing Individualized vs. Weight Based Protocols to Treat VOE in SCD Occlusive Episodes in Sickle Cell Disease

Condition:   Sickle Cell Disease
Interventions:   Other: Patient-Specific Protocol;   Other: Weight-based Protocol;   Drug: Morphine;   Drug: Hydromorphone
Sponsors:   Duke University;   National Heart, Lung, and Blood Institute (NHLBI)
Recruiting

Wed, 01 May 2019 12:00:00 EDT

Effects of Anaesthesia on Inflammatory Markers

Condition:   Inflammatory Response
Interventions:   Drug: Morphine Sulfate;   Drug: morphine+lidocaine;   Drug: Saline
Sponsor:   Assiut University
Recruiting

Mon, 16 Nov 2020 12:00:00 EST

VAS Correlation With BMI

Condition:   Morbid Obesity
Intervention:   Drug: Morphine
Sponsor:   Istanbul University
Unknown status

Fri, 20 Dec 2013 12:00:00 EST

Evaluation of Peripheral Itch Mechanisms Following Injection of Morphine (Second Sub-Project)

Condition:   Itch
Interventions:   Drug: Capsaicin;   Drug: Diphenhydramine;   Drug: Morphine Chloride;   Drug: Isotonic saline;   Drug: Histamine
Sponsor:   Aalborg University
Recruiting

Thu, 07 Jan 2021 12:00:00 EST

Influence of Anesthetic Temperature on Cephalad Sensory Blockade With Spinal Anesthesia

Condition:   Cesarean Delivery
Intervention:   Drug: bupivacaine/fentanyl/morphine
Sponsor:   Nanjing Medical University
Completed

Mon, 29 Dec 2008 12:00:00 EST

CLoWI Versus PCA Morphine for Pain Control After Major Abdominal Surgery

Conditions:   Surgical Wound;   Post-Op Complication;   Opioid Use
Interventions:   Device: CLoWI;   Device: PCA
Sponsor:   JurongHealth
Recruiting

Fri, 07 Aug 2020 12:00:00 EDT

Use of ACUPUNCTURE in Emergency Departement

Conditions:   Age ≥18 Years;   Presigned Consentement to Participate in the Study
Intervention:   Procedure: Acupuncture
Sponsor:   University of Monastir
Completed

Tue, 19 Jun 2012 12:00:00 EDT

Robot-assisted Lobectomy Versus Video-assisted Lobectomy

Conditions:   Robotic Surgical Procedures;   Pneumonectomy; Status;   Anesthesia and Analgesia;   Cardiac Output
Interventions:   Drug: Morphine;   Other: Cardiac output measure
Sponsors:   Hospital Nord;   Gary DUCLOS (Medical Doctor, investigator)
Completed

Thu, 13 Apr 2017 12:00:00 EDT

Acute Post-operative Pain in Colon Resections

Condition:   Analgesia
Interventions:   Device: Sublingual sufentanil tablet system;   Device: Peridural catheter;   Drug: PCA Morphine
Sponsor:   IRCCS San Raffaele
Unknown status

Fri, 19 Jan 2018 12:00:00 EST

Fentanyl Sublingual Tablet or Morphine for the Control of Shortness of Breath During or After Physical Activity in Cancer Patients

Conditions:   Hematopoietic and Lymphoid Cell Neoplasm;   Malignant Solid Neoplasm
Interventions:   Drug: Fentanyl Citrate Buccal Tablet;   Drug: Morphine;   Other: Physical Performance Testing;   Other: Placebo Administration;   Other: Quality-of-Life Assessment;   Other: Questionnaire Administration
Sponsors:   M.D. Anderson Cancer Center;   National Cancer Institute (NCI)
Not yet recruiting

Thu, 05 Dec 2019 12:00:00 EST

Combined Anesthesia for Laparoscopy Surgery in Gynecology

Condition:   Pain
Intervention:   Procedure: Spinal anesthesia with Fentanyl+ Morphine
Sponsor:   Rambam Health Care Campus
Unknown status

Tue, 23 Nov 2010 12:00:00 EST

Does IV Ondansetron Prevent Pruritus After Intrathecal Morphine in Pediatric Patients?

Conditions:   Pruritus;   Nausea/Vomiting
Interventions:   Drug: Ondansetron;   Drug: Placebo Comparator
Sponsor:   University of Michigan
Terminated

Fri, 25 Aug 2017 12:00:00 EDT

Treatment for Chronic Pain in Patients With Advanced Cancer

Conditions:   Chronic Myeloproliferative Disorders;   Leukemia;   Lymphoma;   Multiple Myeloma and Plasma Cell Neoplasm;   Myelodysplastic Syndromes;   Pain;   Precancerous/Nonmalignant Condition;   Small Intestine Cancer;   Unspecified Adult Solid Tumor, Protocol Specific
Interventions:   Drug: dextromethorphan hydrobromide;   Drug: morphine sulfate
Sponsor:   NCIC Clinical Trials Group
Completed

Mon, 27 Jan 2003 12:00:00 EST

Sensory Effects of Oral Opioid Treatment in Patients With Chronic Low Back Pain

Condition:   Low Back Pain
Interventions:   Drug: Oxycodone or morphine sulfate immediate release (MSIR);   Drug: Placebo Treatment
Sponsors:   Brigham and Women's Hospital;   National Institute on Drug Abuse (NIDA)
Recruiting

Wed, 06 Jul 2016 12:00:00 EDT

Comparing Acute Pain Management Protocols for Patients With Sickle Cell Disease

Condition:   Sickle Cell Disease
Interventions:   Drug: Hydromorphone (Standardized, weight-based dosing);   Drug: Morphine Sulfate (Standardized, weight-based dosing);   Drug: Hydromorphone (Patient Specific dosing);   Drug: Morphine Sulfate (Patient Specific dosing)
Sponsors:   Duke University;   National Institutes of Health (NIH);   National Heart, Lung, and Blood Institute (NHLBI);   University of Cincinnati;   Mount Sinai Hospital, New York
Completed

Thu, 21 Aug 2014 12:00:00 EDT

Adding Intra-articular Dexmedetomidine to Levobupivacaine for Postoperative Analgesia in Arthroscopic Knee Surgery

Condition:   Pain
Interventions:   Drug: Levobupivacaine;   Drug: Dexmedetomidine;   Drug: Morphine
Sponsor:   TC Erciyes University
Completed

Thu, 08 Aug 2013 12:00:00 EDT

Bupivacaine Liposome Suspension Versus a Concentrated Multi Drug Periarticular Injection

Condition:   Total Knee Arthroplasty
Interventions:   Drug: bupivacaine liposome suspension;   Drug: concentrated multi drug Ketorlac, Morphine PF, Epinephrine, Ropivicaine, 0.9% NaCL
Sponsor:   TriHealth Inc.
Completed

Mon, 24 Nov 2014 12:00:00 EST

Trial to Shorten Pharmacologic Treatment of Newborns With Neonatal Opioid Withdrawal Syndrome (NOWS)

Condition:   Neonatal Opioid Withdrawal Syndrome
Interventions:   Drug: Morphine;   Drug: Methadone
Sponsors:   Advancing Clinical Trials in Neonatal Opioid Withdrawal (ACT NOW) Program;   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Recruiting

Thu, 02 Jan 2020 12:00:00 EST

Antinociceptive Modalities on Ischemia Reperfusion Injury

Conditions:   End Stage Liver Disease;   Lung Cancer
Intervention:   Drug: Patient controlled analgesia
Sponsor:   National Taiwan University Hospital
Completed

Fri, 30 Aug 2013 12:00:00 EDT

Taste Acuity and Caloric Intake After Acute Morphine Administration

Conditions:   Taste Sweet;   Taste Salty;   Feeding Behavior
Interventions:   Behavioral: taste acuity assessment;   Behavioral: Recorded meal
Sponsors:   Johns Hopkins University;   National Institute on Drug Abuse (NIDA)
Completed

Wed, 09 Jan 2013 12:00:00 EST

Effect of Dexmedetomidine on Gastric Emptying and Gastrointestinal Transit

Conditions:   Gastric Emptying;   Healthy
Interventions:   Drug: Dexmedetomidine;   Drug: Morphine;   Drug: Placebo
Sponsors:   University of Turku;   University of Helsinki
Completed

Wed, 10 Mar 2010 12:00:00 EST

Decreasing REcurrent Pain and Anxiety in Medical Procedures With a Pediatric Population: Trial

Conditions:   Pain;   Burns;   Child;   Anxiety
Interventions:   Device: VR distraction via Oculus Rift;   Drug: Morphine
Sponsor:   St. Justine's Hospital
Withdrawn

Thu, 27 Oct 2016 12:00:00 EDT

Multimodal Analgesia in Major Abdominal Pediatric Cancer Surgeries

Conditions:   Pediatric Cancer;   Pain, Postoperative
Interventions:   Drug: Paracetamol and ketamine;   Procedure: Caudal levobupivacaine;   Drug: Morphine
Sponsor:   National Cancer Institute, Egypt
Completed

Tue, 10 Jul 2018 12:00:00 EDT

A Health Economic Trial in Adult Patients Undergoing Ileostomy Reversal MA402S23B504

Condition:   Retraction of Colostomy
Interventions:   Drug: IV morphine sulfate or Sponsor-approved equivalent;   Drug: EXPAREL
Sponsors:   Pacira Pharmaceuticals, Inc;   Registrat-Mapi
Completed

Fri, 13 Jan 2012 12:00:00 EST

Lidocaine Infusion or Quadratus Lumborum Block and Intrathecal Morphine, Versus Intrathecal Morphine Alone

Condition:   Gynecologic Cancer
Interventions:   Drug: Lidocaine Bolus Infusion;   Procedure: QL block;   Drug: Saline Bolus Infusion;   Procedure: Simulated QL block
Sponsor:   University of Alabama at Birmingham
Terminated

Wed, 05 Sep 2018 12:00:00 EDT

Study in Healthy Volunteers to Investigate the Effects of Quinidine on the Pharmacokinetics of NKTR-118

Condition:   Drug Induced Constipation
Interventions:   Drug: Nektar 118;   Drug: Quinidine;   Drug: Quinidine placebo;   Drug: Morphine
Sponsor:   AstraZeneca
Completed

Wed, 15 Feb 2012 12:00:00 EST

How to Treat Opiate Withdrawal in Neonates

Condition:   Neonatal Abstinence Syndrome
Interventions:   Drug: Phenobarbital;   Drug: Chlorpromazine;   Drug: Morphine
Sponsor:   University of Zurich
Completed

Thu, 23 Jun 2016 12:00:00 EDT

Efficacy of Acupuncture for Prophylaxis of Intrathecal Morphine Induced Pruritis in Patients Undergoing Caesarean Delivery

Conditions:   Acupuncture;   Morphine Induced Pruritis
Interventions:   Device: ACUPUNCTURE AT LI11;   Device: SHAM ACUPUNCTURE
Sponsor:   Letterkenny General Hospital
Completed

Wed, 26 Jan 2011 12:00:00 EST

Functional Restoration After Abdominal and Pelvic Laparoscopic Surgery: Effect of Perioperative Intravenous Lidocaine

Conditions:   Colon Cancer;   Inflammatory Bowel Diseases;   Diverticulitis
Interventions:   Drug: Lidocaine;   Procedure: Epidural Block;   Drug: PCA Morphine
Sponsor:   McGill University Health Centre/Research Institute of the McGill University Health Centre
Completed

Wed, 23 Sep 2009 12:00:00 EDT

Gene Polymorphisms and Morphine Analgesic Consumption

Conditions:   Gene;   Polymorphosis
Intervention:  
Sponsors:   Hamad Medical Corporation;   Qatar University
Recruiting

Mon, 09 Nov 2020 12:00:00 EST

Erector Spinae Block, Epidural Analgesia and Intrathecal Analgesia in Thoracic Surgery

Condition:   Pulmonary Surgery
Interventions:   Procedure: Epidural anesthesia;   Procedure: Intrathecal morphine;   Procedure: Erector spinae block
Sponsor:   University Hospital, Angers
Unknown status

Fri, 01 Nov 2019 12:00:00 EDT

Genetic Predictors of Analgesic Efficacy of Propranolol for Treating Postoperative Pain

Condition:   Postoperative Pain
Interventions:   Drug: Propranolol PO;   Drug: IV-PCA morphine;   Drug: Placebo PO;   Procedure: Quantitative Sensory Testing (QST);   Other: Psychometric assessment;   Genetic: COMT-haplotypes
Sponsor:   McGill University Health Centre/Research Institute of the McGill University Health Centre
Terminated

Thu, 30 Jul 2015 12:00:00 EDT

Multimodal Perioperative Pain Management

Condition:   Degenerative Spondylolisthesis
Interventions:   Drug: Postoperative epidural morphine;   Drug: Local anaesthesia
Sponsors:   Northern Orthopaedic Division, Denmark;   Vejle Hospital;   Aarhus University Hospital;   Copenhagen University Hospital, Denmark
Completed

Fri, 20 Jan 2012 12:00:00 EST

Comparison of a Pain Pump Versus Injectable Medication for Analgesia in Knee Arthroscopy

Condition:   Pain
Interventions:   Device: pain pump containing ropivacaine;   Device: saline pain pump with injectable medication;   Drug: ropivacaine, ketorolac , morphine sulfate
Sponsor:   University of South Alabama
Completed

Wed, 17 Nov 2010 12:00:00 EST

The Analgesic Efficacy of Ultrasound Guided Transversus Abdominal Plane Block After Abdominal Cancer Surgeries

Condition:   Abdominal Cancer
Interventions:   Drug: Bupivacaine (Transversus Abdominis Plane Block);   Drug: Intravenous Patient Controlled Analgesia (PCA) Morphine
Sponsor:   Rajiv Gandhi Cancer Institute & Research Center, India
Completed

Wed, 24 May 2017 12:00:00 EDT

Early Parecoxib Usage to Decreases Narcotic Requirement and Length of Stay After Traumatic Rib Fracture

Conditions:   Parecoxib;   Rib Fractures
Interventions:   Drug: Parecoxib;   Drug: Morphine
Sponsor:   Chang Gung Memorial Hospital
Terminated

Mon, 25 Apr 2016 12:00:00 EDT

Activity Monitoring Assessment of Opiate Withdrawal - 4

Condition:   Opioid-Related Disorders
Intervention:   Drug: Morphine
Sponsors:   National Institute on Drug Abuse (NIDA);   Washington D.C. Veterans Affairs Medical Center
Completed

Tue, 21 Sep 1999 12:00:00 EDT

Spinal Anesthetic for Hip and Knee Replacement Surgery - Intrathecal Morphine or Hydromorphone

Condition:   Spinal Anesthesia
Intervention:   Procedure: spinal anesthesia
Sponsor:   Hopital Montfort
Not yet recruiting

Fri, 21 Feb 2020 12:00:00 EST

NSAIDs With Morphine-PCA Compared to Epidural Analgesia in Thoracotomy Pain

Condition:   Postoperative Pain
Interventions:   Drug: Diclofenac;   Drug: parecoxib/ valdecoxib;   Device: patient controlled epidural analgesia
Sponsors:   Helsinki University Central Hospital;   Academy of Finland
Completed

Wed, 29 Feb 2012 12:00:00 EST

Intrathecal Opioid Study

Condition:   Post-operative Pain
Interventions:   Drug: Morphine100;   Drug: Morphine50;   Drug: Fentanyl;   Drug: Hyperbaric Bupivicaine;   Drug: Indomethacin
Sponsor:   University of Witwatersrand, South Africa
Completed

Fri, 16 Oct 2015 12:00:00 EDT

Cordotomy in Reducing Pain in Patients With Advanced Cancer

Condition:   Advanced Malignant Neoplasm
Interventions:   Procedure: Cordotomy;   Drug: Morphine;   Other: Questionnaire Administration;   Procedure: Sham Intervention
Sponsors:   M.D. Anderson Cancer Center;   National Cancer Institute (NCI);   National Institute of Nursing Research (NINR)
Recruiting

Tue, 08 Oct 2019 12:00:00 EDT

A Trial to Evaluate CG5503 Efficacy and Safety in Acute Pain After Bunionectomy

Conditions:   Bunionectomy;   Pain;   Postoperative Pain;   Acute Pain
Interventions:   Drug: CG5503 IR;   Drug: Morphine;   Drug: Placebo
Sponsors:   Grünenthal GmbH;   Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Completed

Thu, 07 Feb 2008 12:00:00 EST

Epidural Versus Wound Infusion Plus Morphine Bolus in Open Abdominal Aortic Aneurysm Repair

Condition:   Postoperative Pain
Interventions:   Drug: Paracetamol;   Drug: Levobupivacaine wound infiltration;   Drug: Levobupivacaine epidural bolus;   Drug: Sufentanil epidural bolus;   Drug: Morphine;   Device: Epidural catheter placement;   Device: Wound infusion catheters placement;   Drug: Levobupivacaine plus sufentanil epidural infusion;   Drug: Levobupivacaine wound infusion
Sponsor:   University of Genova
Completed

Tue, 09 Feb 2016 12:00:00 EST

Erector Spinae Plane Block for Post-nephrectomy Pain

Condition:   Pain, Postoperative
Interventions:   Procedure: Morphine patient controlled analgesia;   Procedure: Morphine patient controlled analgesia and ESPB
Sponsor:   National Cancer Institute, Egypt
Recruiting

Thu, 03 Sep 2020 12:00:00 EDT

Supra-inguinal Fascia Iliaca Compartment Block on Postoperative Management in Total Hip Arthroplasty by Posterior Approach

Condition:   Arthropathy of Hip
Interventions:   Procedure: Supra-inguinal fascia iliaca compartment block;   Drug: Multimodal analgesia and PCA morphine pump
Sponsor:   University of Liege
Recruiting

Mon, 05 Oct 2020 12:00:00 EDT

Thoracic Paravertebral Blockade in Video Assisted Thoracoscopic Surgery (VATS)

Condition:   Pain, Postoperative
Interventions:   Drug: Thoracic paravertebral block (TPVB);   Drug: Patient Controlled Analgesia (IV PCA)
Sponsor:   Istanbul University
Completed

Thu, 27 Nov 2014 12:00:00 EST

Transversus Abdominis Plane Block and Quadratus Lumborum Block in Pediatric Patients

Condition:   Pain, Postoperative
Intervention:   Drug: Tramadol hydrochloride
Sponsor:   Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Completed

Tue, 24 Dec 2019 12:00:00 EST

Efficacy and Safety of Parecoxib on Morphine Patient-controlled Epidural Analgesia (PCEA) After Gynecologic Surgery

Condition:   Benign Female Reproductive System Neoplasm
Interventions:   Drug: Parecoxib Sodium;   Drug: Normal saline
Sponsors:   Liu Weifeng;   Guangdong Provincial People's Hospital;   Second Affiliated Hospital, Sun Yat-Sen University;   Nanfang Hospital of Southern Medical University
Completed

Thu, 29 Mar 2012 12:00:00 EDT

A Study of Immune Phenotype Biomarkers in Patients With Relapsing Multiple Sclerosis (RMS) After Treatment With 0.5mg Fingolimod

Condition:   Relapsing Multiple Sclerosis
Intervention:   Drug: Fingolimod
Sponsor:   Novartis Pharmaceuticals
Completed

Tue, 22 Aug 2017 12:00:00 EDT

Assessment of Opioid Analgesia in Sickle Cell

Condition:   Sickle Cell Disease
Interventions:   Drug: Dextromethorphan;   Drug: Codeine;   Drug: Morphine
Sponsor:   Children's National Research Institute
Withdrawn

Thu, 09 Aug 2007 12:00:00 EDT

Factors Associated With Failed Spinal Anesthesia for Cesarean Delivery

Conditions:   Anesthesia; Adverse Effect;   Cesarean Section Complications
Intervention:   Procedure: spinal anaesthesia with local anaesthetic and intrathecal morphine
Sponsor:   Mahidol University
Completed

Mon, 28 Dec 2020 12:00:00 EST

Comparing 2 Types of Pain Relief After Cesarean Delivery: Spinal Morphine and TAP Block

Condition:   Cesarean Delivery
Interventions:   Procedure: Placebo block;   Procedure: Ultrasound-guided TAP block
Sponsor:   University of British Columbia
Completed

Mon, 01 Dec 2008 12:00:00 EST

TQLB for Postoperative Pain After Laparoscopic Partial Nephrectomy

Conditions:   Laparoscopic Renal Surgery;   Pain Management;   Nerve Block
Interventions:   Procedure: single-injection TQLB(transmuscular quadratus lumborum block);   Drug: Morphine given as IPCA(intravenous patient controlled analgesia)
Sponsor:   Cui Xulei
Completed

Wed, 12 Jun 2019 12:00:00 EDT

Impact of Adductor Canal Block on Functional Recovery

Condition:   Total Knee Replacement
Interventions:   Procedure: Intrathecal morphine;   Procedure: Adductor Canal block;   Procedure: Peri-articular Infilteration
Sponsor:   Assiut University
Not yet recruiting

Wed, 24 Mar 2021 12:00:00 EDT

A Prospective Randomized Comparison of Fentanyl, Methadone and Morphine for Epidural Analgesia in an Experimental Pain Model

Condition:   Pain
Intervention:   Drug: Epidural administration of bolus
Sponsor:   Hadassah Medical Organization
Withdrawn

Fri, 20 Feb 2009 12:00:00 EST

Spinal Anesthesia For Enhanced Recovery After Liver Surgery

Conditions:   Hepatectomy;   Pain, Postoperative;   Liver Neoplasms
Interventions:   Procedure: Continuous thoracic epidural analgesia;   Procedure: Spinal anesthesia with intrathecal morphine;   Drug: Bupivacaine 0.75% in Dextrose Inj 8.25%;   Drug: Morphine;   Drug: Bupivacaine 0.25% Preservative-Free Injectable Solution;   Drug: Bupicavaine 0.125% epidural solution;   Drug: Hydromorphone 10 mcg/mL epidural solution
Sponsor:   University of Manitoba
Unknown status

Tue, 23 Oct 2018 12:00:00 EDT

Quadratus Lumborum Block in Pediatric Patients

Condition:   Postoperative Pain
Interventions:   Drug: Tramadol Hydrochloride;   Drug: Morphine Sulfate
Sponsor:   Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Completed

Tue, 02 Oct 2018 12:00:00 EDT

Regional Anaesthesia for Painful Injuries After Disasters

Conditions:   Lower Limb Injuries;   Fracture
Interventions:   Drug: Bupivacaine (femoral nerve block);   Drug: Morphine;   Device: Ultrasound
Sponsors:   Epicentre;   Brown University;   Medecins Sans Frontieres, Netherlands
Withdrawn

Thu, 03 Mar 2016 12:00:00 EST

Comparison of Low-dose Ketamine to Opioids in the Management of Acute Pain in Patients Presenting to the Emergency Department With Long Bone Fractures

Condition:   Pain, Acute
Interventions:   Drug: Ketamine;   Drug: Morphine
Sponsor:   The University of Texas Health Science Center, Houston
Not yet recruiting

Mon, 19 Aug 2019 12:00:00 EDT

Ultrasound Guided Pain Control Versus Standard Treatment in Emergency Department HIP Fracture Patients

Condition:   Hip Fracture
Interventions:   Procedure: UFNB (Ultrasound guided femoral nerve block);   Procedure: UFIB (Ultrasound Guided Fascia Iliaca Compartment Block);   Drug: IVMS (IV Morphine)
Sponsors:   Antonios Likourezos;   Emergency Medicine Foundation
Completed

Mon, 22 Jul 2013 12:00:00 EDT

Opioid Rotation From Morphine to Methadone in Treatment of Non-malignant Pain

Condition:   Non-malignant Chronic Pain
Intervention:   Drug: Methadone
Sponsor:   Norwegian University of Science and Technology
Completed

Tue, 25 Jul 2006 12:00:00 EDT

Efficacy of Hylenex in the Treatment of Pain Among Hospice Patients

Condition:   Pain Management
Interventions:   Drug: Hylenex recombinant , morphine, saline;   Other: Saline
Sponsors:   HPC Healthcare, Inc.;   Baxter Healthcare Corporation
Completed

Mon, 22 Oct 2007 12:00:00 EDT

Ultrasound-Guided Versus Conventional Injection for Caudal Block

Condition:   Ultrasound Therapy; Complications
Interventions:   Drug: Levobupivacaine;   Drug: Morphine Sulfate;   Device: Ultrasound
Sponsor:   Ataturk University
Completed

Wed, 08 Nov 2017 12:00:00 EST

Family-Based Treatment for Parental Substance Abuse and Child Maltreatment

Conditions:   Substance Abuse;   Child Abuse;   Child Neglect
Interventions:   Behavioral: Comprehensive Community Treatment;   Behavioral: MST-BSF
Sponsor:   Medical University of South Carolina
Completed

Fri, 03 Aug 2012 12:00:00 EDT

Cervical Erector Spinae Block for Shoulder Surgery

Conditions:   Postoperative Pain;   Shoulder Surgery
Interventions:   Other: Cervical erector spinae plane block;   Device: Intravenous morphine patient controlled analgesia device
Sponsors:   Konya Necmettin Erbakan Üniversitesi;   Ataturk University
Not yet recruiting

Thu, 21 May 2020 12:00:00 EDT

Psoas Compartment Block Versus Fascia Iliaca Block After Total Hip Arthroplasty

Condition:   Pain
Interventions:   Drug: Bupivacaine;   Drug: Morphine
Sponsor:   Hillel Yaffe Medical Center
Unknown status

Thu, 23 Jun 2011 12:00:00 EDT

Efficacy of Intravenous (IV) Paracetamol for Treatment of Acute Pain

Condition:   Acute Pain
Intervention:   Drug: Paracetamol
Sponsor:   Tehran University of Medical Sciences
Completed

Sun, 06 Nov 2011 12:00:00 EDT

Epidural Versus Patient-controlled Analgesia for Reduction in Long-term Mortality Following Colorectal Cancer Surgery

Conditions:   Colorectal Cancer;   Pain;   Other Complications
Interventions:   Drug: Ropivacaine + opioid epidurally;   Drug: Morphine
Sponsors:   Örebro University, Sweden;   University Hospital, Linkoeping
Terminated

Fri, 18 Mar 2011 12:00:00 EDT

Trauma Acute Pain Treatment With Methoxyflurane Vaporized (PENTHROX®): Efficacy and Safety Study (MEDITA)

Condition:   Acute Traumatic Pain
Interventions:   Combination Product: Methoxyflurane and Penthrox inhaler;   Drug: Morphine;   Drug: Paracetamol;   Drug: Ketoprofen
Sponsors:   Mundipharma Pharmaceuticals srl;   Bioikos Ambiente Srl
Completed

Fri, 13 Jul 2018 12:00:00 EDT

Serratus Anterior Plane Block: Post-operative Analgesia in Video-assisted Thoracic Surgery

Conditions:   Regional Anesthesia;   Thoracic Surgery;   Post-operative Pain;   Post-operative Chronic Pain;   Pharmacokinetic Analysis;   Serratus Anterior Plane Block
Interventions:   Procedure: Serratus anterior plane block;   Device: patient-controlled analgesia
Sponsor:   Université Libre de Bruxelles
Unknown status

Mon, 11 Sep 2017 12:00:00 EDT

The Effect of Double Injection Erector Spinae Plane Block on Postoperative Pain Following Breast Surgery

Conditions:   Postoperative Pain;   Breast Cancer
Interventions:   Other: Erector Spinae Plane Block;   Device: Intravenous Morphine patient controlled analgesia device
Sponsor:   Kocaeli University
Completed

Tue, 30 Jan 2018 12:00:00 EST

Combination of Peripheral Nerve Block and DepoDur in Total Knee Joint Replacement

Condition:   Arthroplasty, Replacement, Knee
Interventions:   Drug: Depodur;   Procedure: sciatic nerve block
Sponsors:   University of Louisville;   EKR Therapeutics, Inc
Terminated

Fri, 08 May 2009 12:00:00 EDT

Multisystemic Therapy-Emerging Adults (MST-EA) for Substance Abuse

Condition:   Antisocial Behavior
Interventions:   Behavioral: Multisystemic Therapy-Emerging Adults;   Behavioral: Enhanced Treatment as Usual
Sponsors:   Oregon Social Learning Center;   University of Massachusetts, Worcester;   Connecticut Department of Children and Families;   North American Family Institute;   Court Support Services Division;   Youth Villages
Recruiting

Mon, 30 Jan 2017 12:00:00 EST

Erector Spinae Plane Block for Postoperative Analgesia for Laparoscopic Cholecystectomy

Condition:   Postoperative Pain
Interventions:   Other: erector spinae plane block;   Device: Intravenous morphine patient controlled analgesia device
Sponsor:   Kocaeli University
Completed

Mon, 05 Feb 2018 12:00:00 EST

Study to Assess Safety and Preliminary Activity of Eribulin Mesylate in Pediatric Participants With Relapsed/Refractory Rhabdomyosarcoma (RMS), Non-rhabdomyosarcoma Soft Tissue Sarcoma (NRSTS) and Ewing Sarcoma (EWS)

Conditions:   Relapsed/Refractory Rhabdomyosarcoma;   Non-rhabdomyosarcoma Soft Tissue Sarcoma;   Ewing Sarcoma
Intervention:   Drug: Eribulin mesylate
Sponsor:   Eisai Inc.
Recruiting

Thu, 22 Feb 2018 12:00:00 EST

Intravenous Ketamine for Pain Control During First Trimester Surgical Abortion

Condition:   Abortion in First Trimester
Interventions:   Drug: PO Morphine;   Drug: IV Fentanyl;   Drug: IV Ketamine;   Drug: PO Placebo;   Drug: IV Placebo
Sponsor:   Dr. Marie Eve Sophie Bussiere-Cote
Suspended

Fri, 23 Nov 2018 12:00:00 EST

A Brain Imaging Study of Opioid (Morphine) and Non-opioid (Ketorolac) Conditioning Effects

Condition:   Healthy Controls
Interventions:   Radiation: Integrated MR-PET scan;   Drug: Ketorolac
Sponsor:   Massachusetts General Hospital
Completed

Thu, 12 Apr 2012 12:00:00 EDT

Masked Faces in Parkinson Disease: Mechanism and Treatment

Condition:   Parkinson's Disease
Intervention:   Behavioral: Respiratory muscle strength training
Sponsors:   University of Florida;   National Institute of Neurological Disorders and Stroke (NINDS)
Completed

Mon, 10 Jul 2006 12:00:00 EDT

Continuous Paravertebral Block on Postoperative Quality of Recovery After Hepatectomy

Condition:   Nerve Block
Interventions:   Procedure: Continuous Paravertebral block with ropivacaine;   Procedure: Continuous Paravertebral Block with Saline;   Drug: Patient-controlled analgesia with morphine
Sponsor:   Cui Xulei
Completed

Mon, 17 Dec 2018 12:00:00 EST

Clinical Effectiveness of Erector Spinae Plane Block in Peri-operative Analgesia for Nephrectomy/Nephron Sparing Surgery(NSS) Performed Via Lumbotomy

Condition:   Erector Spinae Plane Block
Interventions:   Drug: Morphine PCA pump;   Procedure: ESP block;   Drug: Fentanyl
Sponsors:   Medical University of Warsaw;   Warsaw Clinical University Center
Unknown status

Fri, 22 Mar 2019 12:00:00 EDT

Epidural Nalbuphine for Postcesarean Epidural Morphine Induced Pruritus

Condition:   Cesarean Section
Interventions:   Drug: nalbuphine;   Other: NSS
Sponsor:   Mahidol University
Completed

Tue, 01 Jul 2008 12:00:00 EDT

Effect of Body Mass Index on the Dose of Intrathecal Hyperbaric Bupivacaine for Elective Cesarean Section

Conditions:   Pain;   Obesity
Intervention:   Drug: bupivacaine 0.75% with fentanyl and morphine
Sponsor:   Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Completed

Mon, 27 Nov 2006 12:00:00 EST

General Plus Spinal Anesthesia and General Anesthesia Alone on Right Ventricular Function

Condition:   Right Ventricular Dysfunction
Interventions:   Procedure: Spinal anesthesia with Bupivacaine heavy and Morphine;   Drug: Bupivacaine heavy and Morphine;   Drug: General Anesthetics
Sponsor:   Postgraduate Institute of Medical Education and Research
Unknown status

Fri, 06 Jan 2017 12:00:00 EST

PEF-Block & Ribs Fractures

Condition:   Chest Trauma With Ribs Fractures
Interventions:   Procedure: Intravenous morphine patient-controlled analgesia (PCA);   Procedure: Block of the posterior exo-thoracic fascia with Ropivacaine;   Procedure: Block of paravertebral space with Ropivacaine
Sponsor:   University Hospital, Montpellier
Unknown status

Thu, 11 Jan 2018 12:00:00 EST

Comparison of Efficacy of Paravertebral and Epidural Analgesia After Videothoracoscopic Lung Lobectomy

Condition:   Lung Cancer
Interventions:   Procedure: Continuous Thoracic Epidural Block;   Procedure: Continuous Thoracic Paravertebral Block;   Procedure: Patient-Controlled Analgesia with Morphine
Sponsor:   Pulmonary Hospital Zakopane
Completed

Mon, 20 Jan 2014 12:00:00 EST

Postoperative Analgesic Effect of Hydromorphone on Partial Pulmonary Resection Under Video-assisted Thoracoscopy

Conditions:   Pain, Postoperative;   Thoracic Surgery, Video-Assisted
Interventions:   Drug: Hydromorphone;   Drug: Morphine
Sponsor:   Second Affiliated Hospital, School of Medicine, Zhejiang University
Completed

Mon, 27 Aug 2018 12:00:00 EDT

Clonidine as Adjunct to Morphine for Neonatal Abstinence Syndrome

Condition:   Neonatal Abstinence Syndrome
Interventions:   Drug: Clonidine;   Drug: Placebo
Sponsor:   Hennepin County Medical Center, Minneapolis
Suspended

Mon, 03 Dec 2018 12:00:00 EST

Discontinuation vs Continuation of Long-term Opioid Therapy in Suboptimal and Optimal Responders With Chronic Pain

Conditions:   Opioid-Related Disorders;   Opiate Addiction;   Narcotic Abuse;   Drug Abuse
Interventions:   Drug: Structured discontinuation of opioid therapy (morphine sulfate ER, oxycodone ER, oxymorphone ER);   Drug: Continuation of opioid therapy (morphine sulfate ER, oxycodone ER, oxymorphone ER)
Sponsor:   Member Companies of the Opioid PMR Consortium
Terminated

Mon, 18 Apr 2016 12:00:00 EDT

CSE for Labour Analgesia: A Comparison of Two Intrathecal Regimens

Condition:   Labor Pain
Interventions:   Drug: Bupivacaine-fentanyl;   Drug: Bupivacaine-fentanyl morphine
Sponsor:   Sarah Beckley
Completed

Tue, 18 Apr 2017 12:00:00 EDT

A Multicentre Study to Evaluate the Safety and Efficacy of AD 923 in Comparison to MSIR for the Treatment of CBP in Subjects

Conditions:   Cancer;   Pain
Intervention:   Drug: AD 923
Sponsor:   Sosei
Terminated

Thu, 13 Mar 2008 12:00:00 EDT

Pilot Study for Testing Safety of Repetitive Magnetic Stimulation for Treatment of Dry Eye

Conditions:   Dry Eye;   Sjogren's Syndrome;   Aqueous Tear Deficiency;   Meibomian Gland Dysfunction;   Dry Eye Syndromes
Intervention:   Device: Ocular Repetitive Magnetic Stimulation (RMS) treatment
Sponsor:   Epitech Mag Ltd.
Completed

Fri, 06 Jan 2017 12:00:00 EST

Peri-Incisional Drug Injection in Lumbar Spine Surgery

Conditions:   Lumbar Disc Herniation;   Degenerative Disc Disease;   Spondylolisthesis
Interventions:   Drug: Morphine;   Drug: Epinephrine;   Drug: naropin
Sponsor:   University of Minnesota
Recruiting

Tue, 01 May 2018 12:00:00 EDT

Pilot Study of the Efficacy and Safety of Q8003 in Patients Who Have Undergone Total Knee Arthroplasty or Total Hip Arthroplasty

Condition:   Postoperative Pain
Interventions:   Drug: Q8003 (morphine sulfate and oxycodone hydrochloride);   Drug: Low dose Q8003 (morphine sulfate and oxycodone hydrochloride);   Drug: Percocet (oxycodone and acetaminophen)
Sponsor:   QRxPharma Inc.
Completed

Wed, 07 Jan 2009 12:00:00 EST

CTPVB for Hepatectomy

Conditions:   Pain Management;   Paravertebral Block;   Hepatectomy
Interventions:   Procedure: Continuous Paravertebral block with ropivacaine;   Procedure: Continuous Paravertebral "block" with saline;   Drug: Patient-controlled analgesia with morphine
Sponsor:   Cui Xulei
Completed

Wed, 19 Jun 2019 12:00:00 EDT

Different Lipid Soluble Opioids for Gynecologic Laparoscopic Surgery Postoperative Patient-controlled Analgesia

Condition:   Post Operative Pain Management
Interventions:   Drug: Sufentanil (R30730, brand name Sufenta);   Drug: Sufentanil (R30730, brand name Sufenta) + Morphine;   Drug: Morphine
Sponsor:   Peking University First Hospital
Completed

Tue, 06 Aug 2013 12:00:00 EDT

Programmed Intermittent Bolus Infusion of Thoracic Paravertebral Block for Hepatectomy

Conditions:   Paravertebral Block;   Hepatectomy;   Analgesia;   Postoperative Recovery
Interventions:   Procedure: Paravertebral block-ropivacaine;   Procedure: Paravertebral block-saline;   Drug: patient controlled analgesia with morphine
Sponsor:   Cui Xulei
Recruiting

Wed, 11 Mar 2020 12:00:00 EDT

Post-operative Pain Relief in Laparoscopic Cholecystectomy

Condition:   Postoperative Pain
Interventions:   Drug: bupivacaine;   Drug: morphine;   Drug: fentanyl;   Drug: Ketamine:
Sponsor:   Assiut University
Unknown status

Tue, 28 Nov 2017 12:00:00 EST

Transversus Abdominus Plane Block in Living Donor Hepatectomy

Condition:   Living Donor Hepatectomy
Interventions:   Device: surgically inserted Transversus abdominus plane catheter;   Drug: Intravenous morphine;   Drug: Bupevecaine;   Drug: Dexmedetomedine
Sponsor:   AlRefaey Kandeel
Completed

Tue, 15 Mar 2016 12:00:00 EDT

Total Knee Arthroplasty Analgesia: Single-shot Femoral Nerve Block or Epidural?

Condition:   Postoperative Pain Treatment for Total Knee Arthroplasty
Interventions:   Drug: Ropivacaine perineural injection;   Drug: morphine and ropivacaine
Sponsor:   Centro Hospitalar do Tâmega e Sousa
Completed

Tue, 17 Jun 2014 12:00:00 EDT

Comparison Between Low-dose Ketamine Infusion and Intravenous Morphine

Condition:   Ketamine
Interventions:   Drug: Ketamine group:;   Drug: Control group
Sponsor:   Cairo University
Completed

Mon, 24 Feb 2020 12:00:00 EST

Dexmedetomidine Addition to Morphine in Patients With Metastatic Cancer

Conditions:   Refractory Pain;   Metastatic Cancer
Intervention:   Drug: Dexmedetomidine
Sponsor:   Hotel Dieu de France Hospital
Completed

Fri, 03 May 2019 12:00:00 EDT

Influence of Patient Choice of Intrathecal Morphine on Post-cesarean Delivery Pain.

Condition:   Pain
Intervention:   Other: Drug Dose
Sponsor:   Stanford University
Completed

Tue, 30 Aug 2011 12:00:00 EDT

Patient-Driven Analgesic Protocol Selection for Post-Cesarean Pain Management

Condition:   Postoperative Pain
Interventions:   Other: No choice given;   Other: Choice given;   Drug: Ibuprofen;   Drug: Acetaminophen;   Drug: Gabapentin;   Drug: Morphine (low);   Drug: Morphine (med);   Drug: Morphine (high)
Sponsor:   Stanford University
Completed

Mon, 16 Nov 2015 12:00:00 EST

Comparison of the Efficacy and Safety of Q8003 Versus Its Individual Components in Bunionectomy Patients

Condition:   Postoperative Pain
Interventions:   Drug: Q8003;   Drug: Morphine sulfate;   Drug: Oxycodone HCl;   Drug: Oxycodone HCl 4mg
Sponsor:   QRxPharma Inc.
Completed

Wed, 28 Jan 2009 12:00:00 EST

Effect of Acute Arterial Hypertension on Morphine's Requirements and Postsurgical Pain.

Conditions:   Hypertensive Disease;   Pain, Postoperative
Interventions:   Other: SBP 20-30% over baseline;   Other: SBP 20-30% under baseline
Sponsor:   Pontificia Universidad Catolica de Chile
Completed

Thu, 11 Jul 2013 12:00:00 EDT

Evaluating the Relationship of Morphine Consumption and Pain-related Molecules in Hepatic Surgical Patients

Conditions:   Pain;   Huntington Disease;   Hepatic Surgery
Intervention:  
Sponsor:   National Cheng-Kung University Hospital
Completed

Thu, 08 Aug 2013 12:00:00 EDT

Effect of Pregabalin on Post Operative Pain in Abdominal Hysterectomy Under Spinal Anesthesia With Intrathecal Morphine

Condition:   Post Operative Pain
Interventions:   Drug: placebo;   Drug: Pregabalin
Sponsor:   Mahidol University
Completed

Thu, 06 Nov 2014 12:00:00 EST

Safety and Pharmacokinetic Study of EMBEDA in Children Ages 7-17 With Pain

Condition:   Moderate-severe Pain
Interventions:   Drug: Ages 7-11;   Drug: ages 12-17
Sponsor:   Pfizer
Terminated

Wed, 02 Apr 2014 12:00:00 EDT

Dexamethasone for Post Cesarean Delivery Analgesia

Condition:   Postoperative Pain
Interventions:   Drug: Dexamethasone;   Drug: Placebo
Sponsor:   University of Iowa
Completed

Tue, 04 Jun 2013 12:00:00 EDT

The Effects of TAP Block on Postsurgical Pain After Minimally Invasive Partial Nephrectomy:

Conditions:   Acute Pain;   Chronic Pain
Interventions:   Procedure: Tap block;   Procedure: intravenous Patient controlled analgesia;   Drug: Morphine;   Drug: Ropivacaine
Sponsor:   Regina Elena Cancer Institute
Completed

Tue, 02 Jun 2015 12:00:00 EDT

Femoral Nerve Block Compared to Exparel in Total Knee Replacement

Conditions:   Osteoarthritis;   Pain
Interventions:   Drug: Exparel;   Drug: Femoral Nerve Block Bupivacaine;   Drug: Toradol;   Drug: Morphine Sulfate
Sponsor:   The New England Baptist Hospital
Unknown status

Tue, 16 Jun 2015 12:00:00 EDT

Efficacy of the Ultrasound-guided Transversus Abdominis Plane Block in Open Aortic Abdominal Aneurysm Repair Surgery

Conditions:   Aortic Aneurysm, Abdominal;   Pain;   Anesthesia, Local
Interventions:   Procedure: TAP block;   Drug: PCA with Chlorhydrate of Morphine;   Drug: Acetaminophen
Sponsor:   Centre Hospitalier Universitaire de Besancon
Unknown status

Mon, 17 Nov 2014 12:00:00 EST

International Prospective Study on Morphine-induced Adverse Drug Reactions in Emergency Departments.

Condition:   Emergencies
Intervention:  
Sponsor:   University Hospital, Toulouse
Completed

Tue, 31 Jul 2012 12:00:00 EDT

Analgesic Efficacy of Morphine Alone or Combined With Paracetamol and/or Ibuprofen for Long-bones Fractures in Children

Conditions:   Pain;   Long-bone Fractures
Interventions:   Drug: Paracetamol;   Drug: Ibuprofen;   Drug: paracetamol + ibuprofen;   Drug: Placebo
Sponsor:   Assistance Publique - Hôpitaux de Paris
Completed

Mon, 22 Jun 2015 12:00:00 EDT

Efficacy of Peri-Incisional Multimodal Drug Injection Following Operative Management of Femur Fractures

Conditions:   Pain, Postoperative;   Femur Fracture
Interventions:   Drug: Ropivacaine;   Drug: Epinephrine;   Drug: Morphine;   Drug: 0.9% sodium chloride solution
Sponsor:   University of Iowa
Completed

Wed, 08 Jun 2016 12:00:00 EDT

Mechanisms of Sleep Disruption Hyperalgesia

Conditions:   Sleep Deprivation;   Pain
Interventions:   Drug: Morphine;   Drug: Saline Placebo;   Behavioral: Forced Awakenings;   Behavioral: Uninterrupted Sleep
Sponsors:   Johns Hopkins University;   National Institute on Drug Abuse (NIDA)
Completed

Wed, 20 Feb 2013 12:00:00 EST

A Study to Evaluate the Abuse Potential of Oxymorphone Compared to Other Mu Opioid Agonists.

Conditions:   Opioid-use Disorder;   Opioid Abuse
Intervention:   Drug: Intravenous Challege Drug
Sponsors:   New York State Psychiatric Institute;   University of Kentucky
Recruiting

Thu, 04 Jan 2018 12:00:00 EST

Prospective Study of Pain After Spinal Morphine for Cesarean Section and Factors Involved in Moderate to Severe Pain

Condition:   Pain, Postoperative
Intervention:  
Sponsor:   Mahidol University
Completed

Sun, 02 Jul 2017 12:00:00 EDT

Effect of Guanfacine on Opioid-induced Hyperalgesia (OIH) and Tolerance

Condition:   Chronic Pain
Interventions:   Drug: Morphine;   Drug: Guanfacine 1mg;   Drug: Guanfacine 2mg;   Drug: Placebo
Sponsors:   Massachusetts General Hospital;   National Institutes of Health (NIH);   National Institute on Drug Abuse (NIDA)
Active, not recruiting

Fri, 07 Sep 2012 12:00:00 EDT

Postoperative Pain, Recovery and Discharge Following Robot-assisted Laparoscopic Prostatectomy

Conditions:   Radical Prostatectomy;   Postoperative Pain
Interventions:   Drug: Bupivacaine;   Drug: Analgesics
Sponsor:   Karolinska Institutet
Recruiting

Tue, 21 Aug 2018 12:00:00 EDT

A Comparison of the Post-C/S Analgesic Effects of Neuraxial Duramorph vs Bilateral TAP Block With Liposomal Bupivacaine

Condition:   Caesarean Section
Intervention:   Drug: Exparel
Sponsor:   Maimonides Medical Center
Terminated

Mon, 20 Aug 2018 12:00:00 EDT

Study of Intensive, Home-Based Family Therapy to Improve Illness Management in Youth With Diabetes

Condition:   Diabetes Mellitus, Insulin Dependent
Interventions:   Behavioral: Intensive Home-Based Family Therapy;   Behavioral: Supportive Telephone Calls
Sponsors:   Wayne State University;   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Completed

Thu, 07 Sep 2006 12:00:00 EDT

Effect of Paracetamol and Ibuprofen Reducing Morphine Requirements After Total Knee Arthroplasty

Condition:   Analgesia
Interventions:   Drug: Paracetamol injection and Ibuprofen injection;   Drug: Paracetamol injection and normal saline;   Drug: Ibuprofen Injection and normal saline
Sponsor:   Indonesia University
Completed

Thu, 04 Jun 2020 12:00:00 EDT

Benefits of Opioid Free Anesthesia on Morphine Consumption in Gastric Bypass

Condition:   Analgesics, Opioid
Interventions:   Drug: Dexmedetomidine Injection [Precedex];   Drug: Remifentanil
Sponsor:   matthieu clanet
Recruiting

Fri, 13 Aug 2021 12:00:00 EDT

Continuous Infusion of Dexamethasone Plus Tramadol Adjunct to Morphine PCA After Abdominal Hysterectomy

Conditions:   Postoperative Pain;   Post Operative Analgesia;   Patient-Controlled Analgesia;   Abdominal Surgeries
Interventions:   Drug: Dexamethasone Sodium Phosphate Injection;   Other: 0.9% Saline
Sponsors:   Nanjing Medical University;   HRSA/Maternal and Child Health Bureau
Completed

Wed, 28 Nov 2007 12:00:00 EST

Intraoperative and Postoperative Analgesia for Laparoscopic Surgery.

Condition:   Analgesia
Interventions:   Drug: morphine;   Drug: intrathecal analgesia (morphine);   Drug: general anesthesia (fentanyl)
Sponsor:   Rambam Health Care Campus
Completed

Wed, 15 Oct 2008 12:00:00 EDT

Local Anesthetic Treatment of Oral Pain in Patients With Mucositis

Condition:   Mucositis
Interventions:   Drug: Bupivacaine;   Drug: Standard treatment (lidocaine viscous solution, morphine, paracetamol, NSAID, gabapentin)
Sponsors:   Hvidovre University Hospital;   Moberg Pharma, Sweden
Completed

Tue, 30 Sep 2014 12:00:00 EDT

Ibuprofen or Morphine in Treating Pain in Patients Undergoing Pleurodesis for Malignant Pleural Effusion

Condition:   Metastatic Cancer
Interventions:   Drug: ibuprofen;   Drug: morphine sulfate;   Procedure: management of therapy complications;   Procedure: pleurodesis
Sponsor:   Oxford University Hospitals NHS Trust
Unknown status

Wed, 26 Mar 2008 12:00:00 EDT

Postoperative Analgesia in Abdominal Surgery: a Medico-economic Study

Conditions:   Extended Ileal Resection Under Laparotomy;   Total Proctocolectomy Under Laparotomy;   Colectomy Left/Right/Total Under Laparotomy;   Rectosigmoidal Resection Under Laparotomy;   Anterior Resection of Rectum Under Laparotomy;   Abdomino-perineal Amputation Under Laparotomy
Interventions:   Procedure: epidural analgesia;   Procedure: PCA
Sponsor:   University Hospital, Limoges
Terminated

Fri, 11 Nov 2011 12:00:00 EST

Morphine-sparing Effect of Intravenous Paracetamol for Post-operative Pain Management Following Laparoscopic Gastric Banding in Morbidly Obese Patients

Condition:   Obesity
Interventions:   Drug: Paracetamol;   Drug: Placebo
Sponsor:   Soroka University Medical Center
Unknown status

Tue, 03 Jun 2014 12:00:00 EDT

Study To Compare Single Dose Of Three Modified Release Formulations Of PF-04937319 With Immediate Release Material-Sparing-Tablet (IR MST) Formulation Previously Studied In Adults With Type 2 Diabetes Mellitus.

Condition:   Type 2 Diabetes Mellitus
Interventions:   Drug: PF-04937319 IR MST;   Drug: PF-04937319 MR 1;   Drug: PF-04937319 MR 2;   Drug: PF-04937319 MR 3
Sponsor:   Pfizer
Completed

Fri, 01 Aug 2014 12:00:00 EDT

Open Radical Prostatectomy and Erector Spinae Plane Block

Conditions:   Prostate Cancer;   Anesthesia, Local;   Pain, Postoperative
Interventions:   Procedure: Single-injection ultrasound-guided bilateral erector spinae plane (ESP) block-Sham;   Procedure: Single-injection ultrasound-guided bilateral erector spinae plane block-Lidocaine/Bupivacaine;   Other: Pain follow-up and monitorization
Sponsors:   BURHAN DOST;   Ondokuz Mayıs University
Completed

Tue, 07 Apr 2020 12:00:00 EDT

The Effect of Chlorzoxazone on Moderate to Severe Postoperative Pain After Spine Surgery

Conditions:   Chlorzoxazone;   Postoperative Pain
Interventions:   Drug: Placebo;   Drug: Chlorzoxazone;   Drug: Morphine;   Drug: Zofran
Sponsors:   Rigshospitalet, Denmark;   Glostrup University Hospital, Copenhagen
Completed

Mon, 02 Sep 2013 12:00:00 EDT

Methadone in Ambulatory Surgery

Conditions:   Post-operative Pain;   Anesthesia
Interventions:   Drug: methadone;   Drug: Control (Intra-operative administration of opioids, other than methadone)
Sponsor:   Washington University School of Medicine
Completed

Mon, 24 Nov 2014 12:00:00 EST

Preemptive Oral Gabapentin 600 mg in Reducing Morphine Requirement After Non Obstetric Lower Abdominal Surgery

Condition:   Non-obstetric Lower Abdominal Surgery
Interventions:   Drug: Gabapentin;   Other: Placebo
Sponsor:   Indonesia University
Completed

Tue, 16 Jun 2020 12:00:00 EDT

Analgesic Efficacy of Transmuscular Quadratus Lumborum in Patients Undergoing Total Abdominal Hysterectomy

Condition:   Pain Postoperative
Interventions:   Procedure: Transmuscular quadratus lumborum block;   Drug: morphine;   Drug: ropivacaine
Sponsor:   Kuala Lumpur General Hospital
Completed

Mon, 26 Oct 2015 12:00:00 EDT

Opioid/Benzodiazepine Polydrug Abuse: Aim 3

Conditions:   Opioid Abuse;   Benzodiazepine Abuse;   Polysubstance Abuse
Interventions:   Drug: Morphine;   Drug: Alprazolam;   Drug: Placebo
Sponsors:   Wayne State University;   Henry Ford Health System
Not yet recruiting

Mon, 16 Aug 2021 12:00:00 EDT

Comparison of Three Opioid Detoxification Treatment Regimens

Conditions:   Opioid-Related Disorders;   Opioid Withdrawal
Interventions:   Drug: Buprenorphine/naloxone;   Drug: Morphine;   Drug: Tramadol
Sponsor:   University of Alabama at Birmingham
Withdrawn

Thu, 20 Sep 2018 12:00:00 EDT

RCT of Epinephrine (None, 100mcg, and 200mcg) in a Hyperbaric Bupivacaine, Fentanyl and Morphine Spinal in C-sections.

Conditions:   Pregnancy;   Cesarean Section
Interventions:   Drug: 100 mcg Epinephrine;   Other: normal saline;   Drug: 200 mcg Epinephrine
Sponsor:   University of Florida
Withdrawn

Tue, 07 Nov 2017 12:00:00 EST

Erector Spinae Plane Block for Rib Fracture Analgesia in the Emergency Department

Condition:   Rib Fracture Multiple
Interventions:   Procedure: Erector Spinae Plane Block;   Drug: IV Analgesia
Sponsor:   University of Southern California
Not yet recruiting

Wed, 19 May 2021 12:00:00 EDT

Transcultural Validation of MSTS and TESS Questionnaire

Condition:   Cancer
Intervention:  
Sponsors:   Nantes University Hospital;   University Hospital, Angers
Unknown status

Wed, 05 Dec 2018 12:00:00 EST

MST in Patients With Inflammatory Rheumatic Disease

Condition:   Inflammatory Rheumatism
Intervention:   Behavioral: Maximal strength training
Sponsor:   Molde University College
Completed

Tue, 10 Aug 2021 12:00:00 EDT

A Study to Asses Efficacy, Safety and Tolerability of Monthly Long-acting IM Injection of GA Depot in Subjects With RMS

Condition:   Multiple Sclerosis, Relapsing-Remitting
Interventions:   Drug: GA Depot;   Other: Placebo
Sponsor:   Mapi Pharma Ltd.
Active, not recruiting

Wed, 09 Oct 2019 12:00:00 EDT

IV PCA With or Without Continuous Dose vs Oral Opioid to Maintain Analgesia for Severe Cancer Pain After Successful Titration

Condition:   Cancer Pain
Interventions:   Drug: Hydromorphone Hydrochloride Injection;   Drug: Morphine Sulfate Sustained-release Tablets
Sponsor:   Fujian Cancer Hospital
Not yet recruiting

Mon, 08 Mar 2021 12:00:00 EST

Double Blind Efficacy and Safety Study of Flexible-Dose vs Low-Dose Q8003 After Undergoing Primary Unilateral Total Knee Arthroplasty

Condition:   Postoperative Pain
Interventions:   Drug: Flexible dose Q8003 (morphine sulfate and oxycodone hydrochloride);   Drug: Low dose Q8003 (morphine sulfate and oxycodone hydrochloride)
Sponsor:   QRxPharma Inc.
Completed

Mon, 25 Jan 2010 12:00:00 EST

Gabapentin for Prophylaxis Intrathecal Morphine-Induced Pruritus

Condition:   Pruritus
Intervention:   Drug: Gabapentin
Sponsor:   Prince of Songkla University
Completed

Tue, 09 Nov 2010 12:00:00 EST

Effects of Epidural Lidocaine on the Pharmacokinetic and Pharmacodynamic Profiles of DepoDur® After Cesarean Delivery

Condition:   Epidural Analgesia, Obstetric
Interventions:   Drug: DepoDur following epidural lidocaine;   Drug: DepoDur following spinal anesthetic
Sponsor:   Stanford University
Completed

Tue, 09 Dec 2008 12:00:00 EST

Efficacy of Multimodal Periarticular Injections in Operatively Treated Ankle Fractures

Conditions:   Pain, Postoperative;   Ankle Fractures
Interventions:   Drug: Ropivacaine;   Drug: Epinephrine;   Drug: Morphine;   Drug: 0.9% sodium chloride solution
Sponsor:   Kyle Hancock
Completed

Fri, 18 Nov 2016 12:00:00 EST

Mechanisms of Hypoglycemia Associated Autonomic Failure

Conditions:   Diabetes Mellitus;   Hypoglycemia;   Autonomic Failure
Interventions:   Drug: naloxone;   Dietary Supplement: fructose;   Behavioral: exercise;   Drug: Morphine sulfate;   Drug: Epinephrine
Sponsors:   Albert Einstein College of Medicine;   National Institutes of Health (NIH);   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Active, not recruiting

Thu, 15 May 2008 12:00:00 EDT

Patient Controlled Analgesia Pump Cues on Patient Satisfaction

Condition:   Postoperative Pain
Interventions:   Device: Patient-Controlled Analgesia pump with Cues;   Device: Patient-Controlled Analgesia pump without Cues;   Drug: Morphine
Sponsors:   Medical College of Wisconsin;   Children's Hospital and Health System Foundation, Wisconsin
Completed

Fri, 29 May 2015 12:00:00 EDT

Estimation of the Effective Dose (ED) 95 of Intrathecal Hyperbaric Prilocaine 2% for Scheduled Cesarean Delivery.

Condition:   Pregnant Women
Interventions:   Drug: Hyperbaric prilocaine 2%;   Drug: Morphine
Sponsor:   Centre Hospitalier Universitaire Saint Pierre
Completed

Tue, 31 Jul 2018 12:00:00 EDT

Continuous Local Anesthetic and Steroid Infusion in Abdominal Surgery

Condition:   Abdominal Pain
Interventions:   Drug: ropivacaine 0.2%;   Drug: Methylprednisolone 1mg/kg;   Drug: saline 0.9%
Sponsor:   IRCCS Policlinico S. Matteo
Completed

Fri, 06 Dec 2013 12:00:00 EST

Automated urIne Flow Detection to Reduce Errors and Nursing Workload

Conditions:   Acute Kidney Injury;   Kidney Injury
Intervention:   Device: Clarity RMS Electronic Sensor
Sponsors:   University of Pittsburgh;   RenalSense Ltd
Completed

Fri, 17 Aug 2018 12:00:00 EDT

Atropine to Prevent Nausea and Vomiting After Spinal Anesthesia for Caesarean Section

Conditions:   Cesarean Section;   Anesthesia,Spinal;   Postoperative Nausea and Vomiting
Interventions:   Drug: Bupivacaine;   Drug: Morphine;   Drug: Isotonic saline solution;   Drug: Atropine
Sponsor:   University of Parma
Completed

Tue, 16 Jun 2009 12:00:00 EDT

A PhaseⅡ/ Ⅲ Seamless Study to Evaluate Efficacy and Safety of Paracetamol Injection as Adjuvant to Morphine-based Postoperative Analgesia

Condition:   Post-operative Analgesia
Interventions:   Drug: Paracetamol injection;   Drug: Normal Saline injection;   Drug: Morhpine PCA
Sponsor:   Jiangsu HengRui Medicine Co., Ltd.
Completed

Thu, 23 Jun 2016 12:00:00 EDT

Implications of Different Analgesic Models on Inflammatory Markers After Laparoscopic Cholecystectomy

Condition:   Perioperative Pain
Interventions:   Drug: Bupivacaine;   Drug: isotonic saline;   Drug: Bupivacaine + morphine;   Drug: Bupivacaine + morphine + ketamine
Sponsor:   Assiut University
Completed

Fri, 30 Oct 2020 12:00:00 EDT

Morphine Gel for Bedsores

Condition:   Decubitus Ulcer
Intervention:   Drug: Pain relief for pressure ulcers
Sponsors:   University of Kansas;   National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Completed

Mon, 18 Dec 2000 12:00:00 EST

Controlled-Release Oxycodone For Postoperative Analgesia After Video-Assisted Thoracic Surgery

Conditions:   Anesthesia Recovery Period;   Pain, Postoperative
Interventions:   Drug: Morphine;   Drug: oxycodone;   Procedure: Paravertebral block;   Drug: Propofol;   Drug: Remifentanil;   Drug: Paracetamol
Sponsor:   University of Parma
Terminated

Wed, 21 May 2008 12:00:00 EDT

Prevention of Intrathecal Morphine Induced Pruritus: Comparison of Ondansetron and Palonosetron

Condition:   Morphine Adverse Reaction
Interventions:   Drug: Ondansetron;   Drug: Palonosetron
Sponsor:   Kyungpook National University Hospital
Completed

Mon, 30 Sep 2013 12:00:00 EDT

Study of Oliceridine (TRV130) for the Treatment of Moderate to Severe Acute Pain After Bunionectomy

Condition:   Acute Pain
Interventions:   Drug: Oliceridine;   Drug: Placebo;   Drug: Morphine
Sponsor:   Trevena Inc.
Completed

Tue, 28 Jun 2016 12:00:00 EDT

Efficacy of Prevention for Postoperative Nausea and Vomiting After Intrathecal Morphine in Cesarean Section

Conditions:   Pregnancy;   PONV
Interventions:   Drug: dexamethasone;   Drug: dexamethasone 5 mg
Sponsor:   Mahidol University
Unknown status

Tue, 05 May 2009 12:00:00 EDT

Outpatient Adolescent Treatment for Comorbid Substance Use and Internalizing Disorders

Conditions:   Substance-Related Disorders;   Depressive Disorder;   Anxiety Disorder
Interventions:   Behavioral: Outpatient MST/OPTION-A;   Behavioral: Usual Services
Sponsors:   Medical University of South Carolina;   National Institute on Drug Abuse (NIDA)
Completed

Thu, 22 Feb 2007 12:00:00 EST

Evaluation of the Tolerability of Switching Subjects on Chronic ATC Opioid Therapy to Buprenorphine HCl Buccal Film

Condition:   Pain
Interventions:   Drug: Buprenorphine;   Drug: Placebo film;   Drug: Oxycodone;   Drug: Morphine sulfate;   Drug: Placebo capsule
Sponsor:   BioDelivery Sciences International
Completed

Thu, 06 Jun 2013 12:00:00 EDT

Ondansetron vs Ondansetron Plus Dexamethasone for Relieving Intrathecal Morphine Side Effects After C-section

Conditions:   Pruritus;   Cesarean Section
Interventions:   Drug: Ondansetron (Zofran);   Drug: Dexamethasone (Decadron);   Other: Spinal anesthesia
Sponsor:   Makassed General Hospital
Completed

Wed, 08 Jun 2016 12:00:00 EDT

Study of Oliceridine (TRV130) for the Treatment of Moderate to Severe Acute Pain After Abdominoplasty

Condition:   Acute Pain
Interventions:   Drug: Oliceridine;   Drug: Placebo;   Drug: Morphine
Sponsor:   Trevena Inc.
Completed

Thu, 30 Jun 2016 12:00:00 EDT

Determinants of Oral Morphine Answer Among Obese Patients Before and After Gastric Bypass

Condition:   Obesity
Intervention:   Procedure: gastric bypass
Sponsor:   Hopital Lariboisière
Completed

Wed, 22 Jul 2009 12:00:00 EDT

Comparison of Erector Spinae Plane Block With Thoracic Paravertebral Block for Breast Surgery

Conditions:   Postoperative Pain;   Breast Cancer
Interventions:   Device: Intravenous morphine patient controlled device;   Other: Erector Spinae Plane Block;   Other: Thoracic Paravertebral Block
Sponsor:   Kocaeli University
Completed

Thu, 29 Mar 2018 12:00:00 EDT

The Effect of the Transversus Abdominis Plane Block to Postoperative Analgesia for Cesarean Section

Condition:   Obstetric Pain
Interventions:   Procedure: TAP block;   Drug: Morphine;   Drug: Ropivacaine
Sponsor:   Gia Dinh People Hospital
Completed

Thu, 16 Aug 2018 12:00:00 EDT

Postoperative Epidural Analgesia in Spine Fusion Surgery

Condition:   Pain
Interventions:   Drug: 0.125% Bupivacaine HCL @ 4-5 ml/h;   Drug: 0.125% Bupivacaine HCL , Morphine sulphate @ 3 mg 3-5 ml/h;   Drug: 0.125% Bupivacaine, Fentanyl 100 mic @ 3-5 ml/h
Sponsor:   Assiut University
Completed

Wed, 24 Apr 2013 12:00:00 EDT

Study of Efficacy and Safety of Fingolimod (Gilenya) 0.5 mg in Chinese Patients With Relapsing Multiple Sclerosis (RMS) Patients

Condition:   Relapsing Multiple Sclerosis (RMS)
Intervention:   Drug: Fingolimod 0.5mg
Sponsor:   Novartis Pharmaceuticals
Recruiting

Wed, 16 Dec 2020 12:00:00 EST

Study on Impact of Maximal Strength Training in Patients With COPD

Condition:   Chronic Obstructive Pulmonary Disease
Interventions:   Other: Maximal strenght training (MST) plus endurance training (ET);   Other: Endurance training (ET)
Sponsors:   Istituti Clinici Scientifici Maugeri SpA;   Universita di Verona
Recruiting

Thu, 10 Jan 2019 12:00:00 EST

Bilateral vs. Unilateral Erector Spinae Plane Block

Conditions:   Postoperative Pain;   Cholecystitis; Gallstone
Interventions:   Procedure: Bilateral ESP Block;   Procedure: Unilateral ESP Block;   Device: Intravenous Morphine patient controlled analgesia device
Sponsor:   Kocaeli University
Completed

Thu, 20 Dec 2018 12:00:00 EST

Aromatherapy for Prevention of Intrathecal Morphine Induced Nausea and Vomiting

Condition:   Post Operative Nausea and Vomiting
Interventions:   Biological: Peppermint essential oil;   Drug: Granisetron;   Drug: Dexamethasone
Sponsor:   Universiti Kebangsaan Malaysia Medical Centre
Completed

Thu, 15 Feb 2018 12:00:00 EST

Metabolites of Tramadol in the Postoperative Surgical Patients

Conditions:   Abdominal Surgery;   Respiratory Failure;   Renal Failure;   Liver Dysfunction;   Multiorgan Failure
Intervention:   Drug: Postoperative analgesia using tramadol
Sponsors:   Osijek University Hospital;   Josip Juraj Strossmayer University of Osijek
Completed

Tue, 02 Jul 2019 12:00:00 EDT

Surgicel and Analgesic Reservoir

Condition:   Postoperative Pain
Interventions:   Drug: "Local Anesthetic", "Epinephrine" and "Morphine";   Drug: "Local Anesthetic", "Epinephrine", "Morphine" and "Surgicel";   Drug: "Normal Saline"
Sponsor:   Assiut University
Completed

Mon, 05 Nov 2018 12:00:00 EST

The Match Study in ESRD Patients

Condition:   Dialysis Access Malfunction
Intervention:   Device: Alio Medical Remote Monitoring System (RMS)
Sponsor:   Alio Medical
Not yet recruiting

Mon, 07 Jun 2021 12:00:00 EDT

10% Carbohydrate Drink for Preventing Post-operative Nausea and Vomiting (PONV) After Spinal Morphine

Condition:   Nausea and Vomiting, Postoperative
Intervention:   Dietary Supplement: 10% carbohydrate drink
Sponsor:   Mahidol University
Completed

Wed, 23 Feb 2011 12:00:00 EST

Analgesia and Pancreatic Cancer Surgery

Condition:   Pancreatic Neoplasms
Interventions:   Procedure: Epidural patient controlled analgesia;   Drug: Intravenous patient controlled analgesia
Sponsor:   National Taiwan University Hospital
Unknown status

Wed, 28 Aug 2013 12:00:00 EDT

Oral Oxycodone After Major Cardiac Surgery

Condition:   Heart; Dysfunction Postoperative, Cardiac Surgery
Interventions:   Drug: Targin;   Drug: Oxynorm;   Drug: Morphine
Sponsor:   Medical University of Vienna
Completed

Fri, 22 Mar 2013 12:00:00 EDT

Quality of Recovery After Dexamethasone, Ondansetron or Placebo Intrathecal Morphine Administration

Conditions:   Fractures, Bone;   Nausea and Vomiting, Postoperative;   Pruritus;   Morphine Adverse Reaction;   Satisfaction, Personal
Interventions:   Drug: Dexamethasone;   Drug: Ondansetron;   Drug: Saline
Sponsor:   Pontificia Universidade Catolica de Sao Paulo
Completed

Mon, 30 Jan 2017 12:00:00 EST

Clinical Effectiveness of Erector Spinae Plane Block in Peri-operative Analgesia for Laparoscopic Nephrectomy/Nephron Sparing Surgery (NSS)/Hynes-Anderson Procedures.

Condition:   Erector Spinae Plane Block
Interventions:   Procedure: bilateral ESP block with 0,25% Bupivacaine+ Adrenaline;   Procedure: ESP block continuous infusion with 0,125% Bupivacaine+Adrenaline;   Drug: Morphine PCA pump
Sponsor:   Medical University of Warsaw
Recruiting

Thu, 14 Mar 2019 12:00:00 EDT

Morphine Consumption in Thoracotomy

Condition:   Postoperative Pain
Interventions:   Procedure: PVB;   Procedure: ESPB
Sponsor:   Kocaeli University
Recruiting

Tue, 10 Aug 2021 12:00:00 EDT

Initial Pain Management in Pediatric Pancreatitis: Opioid vs. Non-Opioid

Condition:   Acute Pancreatitis
Interventions:   Drug: Ketorolac;   Drug: Opioid
Sponsors:   Boston Children's Hospital;   The National Pancreas Foundation
Not yet recruiting

Mon, 02 Mar 2020 12:00:00 EST

Buprenorphine's Dose Response Curve

Condition:   Opioid-related Disorders
Interventions:   Drug: Buprenorphine;   Drug: Morphine;   Drug: Placebo
Sponsors:   Johns Hopkins University;   National Institute on Drug Abuse (NIDA)
Completed

Fri, 13 Apr 2007 12:00:00 EDT

Evaluation of the Use of Spinal Epimorph in Total Knee Arthroplasty

Conditions:   Post-operative Pain;   Osteoarthritis
Interventions:   Drug: Epimorph;   Drug: Spinal analgesia
Sponsor:   Lawson Health Research Institute
Completed

Fri, 17 Aug 2012 12:00:00 EDT

Postoperative Belladonna and Morphine Suppositories in Vaginal Surgery

Condition:   Vaginal Surgery
Interventions:   Drug: Belladonna and Opium Suppositories;   Drug: Placebo Suppositories
Sponsor:   Kristina A. Butler
Completed

Fri, 25 Jun 2010 12:00:00 EDT

Open Label Randomized Multicenter to Assess Efficacy & Tolerability of Ofatumumab 20mg vs. First Line DMT in RMS

Condition:   Multiple Sclerosis
Interventions:   Drug: Ofatumumab;   Drug: First line DMT
Sponsor:   Novartis Pharmaceuticals
Recruiting

Tue, 09 Mar 2021 12:00:00 EST

Intrathecal Morphine Microdose Method Sensory Changes

Conditions:   Analgesic Drug Dependence;   Sensory Disorders;   Chronic Pain
Interventions:   Behavioral: Quantitative Sensory Tests;   Behavioral: surveys
Sponsor:   The University of Texas Medical Branch, Galveston
Recruiting

Wed, 10 Jan 2018 12:00:00 EST

Pharmacogenetic Morphine Spine Study

Condition:   Pain
Intervention:  
Sponsor:   Children's Hospital Medical Center, Cincinnati
Completed

Wed, 24 Apr 2013 12:00:00 EDT

Effects of Osteoarthritis Pain, Morphine, and Placebo on Neuroendocrine Function in Men

Condition:   Osteoarthritis
Intervention:   Procedure: Blood Draw
Sponsor:   National Center for Complementary and Integrative Health (NCCIH)
Completed

Mon, 26 Jul 2004 12:00:00 EDT

Effect of Epidural Anesthesia and Analgesia on Quality of Recovery After Radical Prostatectomy.

Conditions:   Anesthesia;   Anesthesia Recovery Period;   Radical Prostatectomy;   Patient Satisfaction;   Postoperative Period;   Quality of Life;   Analgesia;   Epidural;   Quality of Recovery
Interventions:   Procedure: Epidural anesthesia with light general anesthesia;   Drug: Postoperative epidural analgesia;   Procedure: General anesthesia;   Drug: Continuous intravenous analgesia
Sponsor:   University Hospital of Split
Completed

Wed, 14 Oct 2020 12:00:00 EDT

Multimodal Analgesia Strategies After Major Shoulder Ambulatory Surgery

Condition:   Tendon Injuries
Interventions:   Drug: Tramadol;   Drug: Nefopam 20 MG/ML;   Drug: Morphine Sulfate;   Drug: Oxycodone 20mg
Sponsor:   Centre Hospitalier Universitaire de Nīmes
Unknown status

Tue, 01 Oct 2019 12:00:00 EDT

Effect of Epidural Anesthesia and Analgesia on Quality of Recovery After Unilateral Nephrectomy.

Conditions:   Anesthesia;   Anesthesia Recovery Period;   Nephrectomy;   Patient Satisfaction;   Postoperative Period;   Quality of Life;   Analgesia;   Epidural
Interventions:   Procedure: Epidural anesthesia with light general anesthesia;   Procedure: Postoperative epidural analgesia;   Procedure: General anesthesia;   Drug: Continuous intravenous analgesia
Sponsor:   University Hospital of Split
Completed

Thu, 20 Aug 2020 12:00:00 EDT

Ultrasound Guided Single Shot Block of Posterior Tibial Nerve for Postoperative Pain Relief After Hallux Valgus Surgery

Condition:   Hallux Valgus
Interventions:   Drug: Ropivacaine 0,75%;   Procedure: posterior tibial nerve block;   Drug: morphine and droperidol
Sponsor:   Dr.med. Sabine Schoenfeld
Unknown status

Wed, 05 Nov 2014 12:00:00 EST

Effect of Dexmedetomidine on Postoperative Glucose and Insulin Levels.

Conditions:   Bariatric Surgery Candidate;   Glucose Intolerance;   Insulin Resistance
Interventions:   Drug: Dexmedetomidine;   Drug: 0.9% Sodium-chloride;   Drug: Fentanyl;   Drug: Morphine Sulfate
Sponsor:   Pontificia Universidad Catolica de Chile
Completed

Fri, 18 Jan 2019 12:00:00 EST

Electro-Magnetic Convulsive Therapies for Depression: a Non-inferiority Study

Conditions:   Major Depressive Disorder;   Bipolar Depression
Interventions:   Device: Magnetic Seizure Therapy;   Device: Electroconvulsive Therapy
Sponsors:   University of Sao Paulo;   Fundação de Amparo à Pesquisa do Estado de São Paulo
Recruiting

Thu, 23 Sep 2021 12:00:00 EDT

Paravertebral Analgesia Associated With Intravenous Morphine PCA After Thoracotomy

Condition:   Pain
Interventions:   Drug: ropivacaine;   Other: nacl 0,9%
Sponsor:   University Hospital, Strasbourg, France
Completed

Thu, 21 Feb 2008 12:00:00 EST

The Effect of Intraoperative Ketamine on Opioid Consumption and Pain After Spine Surgery in Opioid-dependent Patients

Conditions:   Postoperative Pain;   Chronic Pain;   Analgesics
Interventions:   Drug: (S)-(+)-Ketamine Hydrochloride Solution 25 mg/ml;   Drug: Isotonic sodium chloride 0.9 percent;   Drug: Paracetamol 1 g;   Drug: Morphine Sulphate 1 mg/ml;   Drug: Ondansetron 2 mg/ml;   Drug: Usual daily opioids;   Drug: Sufentanil 5 microgram/ml
Sponsors:   Rigshospitalet, Denmark;   Glostrup University Hospital, Copenhagen
Completed

Thu, 13 Mar 2014 12:00:00 EDT

Multimodal Opioid-free Anesthesia Versus Opioid-based Anesthesia for Patients Undergoing Cardiac Valve Surgeries: RCT

Condition:   Anesthesia
Interventions:   Drug: Dexmedetomidine 0.5 mic/kg/h;   Drug: Fentanyl 1 mic/kg/hr
Sponsor:   Cairo University
Recruiting

Tue, 01 Dec 2020 12:00:00 EST

Multisystemic Therapy to Reduce Health Disparities in Adolescents With Asthma

Condition:   Asthma
Interventions:   Behavioral: Multisystemic Therapy;   Behavioral: Home-based, Non-Directive Family Support
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Completed

Tue, 09 Jun 2009 12:00:00 EDT

An Open-label Evaluation of Tapentadol Extended Release (ER) in Participants With Moderate to Severe Chronic Pain After Conversion From Hydrocodone, Oxycodone Controlled Release (CR), and/or Morphine Sustained Release (SR)

Conditions:   Pain;   Chronic Back Pain;   Chronic Low Back Pain;   Osteoarthritis Pain In The Hip or Knee
Intervention:   Drug: Nucynta ER
Sponsor:   Janssen Scientific Affairs, LLC
Withdrawn

Fri, 29 Jun 2012 12:00:00 EDT

Erector Spinae Plane Block in Scoliotic Adolescents

Conditions:   Scoliosis Idiopathic;   Scoliosis; Adolescence;   Erector Spinae Plane Block
Interventions:   Procedure: Erector Spinae Plane Block;   Drug: Fentanyl;   Drug: additional Fentanyl;   Drug: Morphine;   Drug: rescue Morphine;   Drug: pethidine;   Drug: Ketorolac;   Drug: Acetaminophen
Sponsor:   Kasr El Aini Hospital
Completed

Thu, 30 May 2019 12:00:00 EDT

A Pilot Study of the Use of Magnetic Seizure Therapy for Depression

Condition:   Treatment Resistant Depression
Intervention:   Device: MST
Sponsor:   Bayside Health
Completed

Tue, 16 Dec 2008 12:00:00 EST

Hemodynamic Effects of Low Dose Spinal Anesthesia for Cesarean Section

Conditions:   Complications; Cesarean Section;   Effects of; Anesthesia, Spinal and Epidural, in Pregnancy;   Hemodynamic Instability;   Personal Satisfaction
Interventions:   Drug: Bupivacaine 4.5;   Drug: Bupivacaine 9;   Drug: Morphine;   Drug: Fentanyl
Sponsor:   University of Manitoba
Terminated

Wed, 15 Jan 2014 12:00:00 EST

24-hour Oral Morphine Equivalent Based Opioid Prescribing After Surgery

Condition:   Opioid Use
Interventions:   Other: Arm 1 Prescription As Usual;   Other: Arm 2 Prescription Tool Intervention
Sponsors:   University of Colorado, Denver;   National Institute on Drug Abuse (NIDA)
Completed

Fri, 02 Aug 2019 12:00:00 EDT

Predict MDE Outcomes After MST

Condition:   Major Depressive Episode
Interventions:   Device: Magpro X100 + Option;   Device: ThymatronSystem Ⅳ Electroconvulsive System
Sponsor:   Shanghai Mental Health Center
Recruiting

Fri, 15 Feb 2019 12:00:00 EST

Dexmedetomidine to Treat Bariatric Surgery-associated Pain

Condition:   Obesity
Interventions:   Drug: Fentanyl;   Drug: Morphine;   Drug: Dexmedetomidine
Sponsor:   Janelle Vaughns
Completed

Fri, 26 Aug 2016 12:00:00 EDT

Ketamine Low dOse Evaluation on Morphine Consumption in Traumatic Patient

Condition:   Traumatic Injury
Intervention:   Drug: Administration of drug
Sponsor:   Assistance Publique Hopitaux De Marseille
Not yet recruiting

Tue, 06 Apr 2021 12:00:00 EDT

Subcutaneous Bupivacaine Decrease Post-op Pain in Patients Undergoing C-Section

Condition:   Pain, Referred
Interventions:   Drug: Bupivacaine;   Drug: Morphine;   Drug: Fentanyl;   Drug: Epinephrine;   Other: Saline solution
Sponsor:   Montefiore Medical Center
Terminated

Tue, 26 Dec 2017 12:00:00 EST

Dexmedetomidine for Morphine Consumption Reduction (DEXDOR)

Condition:   Burning
Intervention:  
Sponsor:   Centre Hospitalier Régional Metz-Thionville
Completed

Mon, 19 Sep 2016 12:00:00 EDT

Comparisons of iv Ibuprofen and iv Paracetamol During Bariatric Surgery

Conditions:   Bariatric Surgery Candidate;   Obesity, Morbid
Interventions:   Drug: paracetamol;   Drug: ibuprofen
Sponsor:   Inonu University
Completed

Fri, 20 May 2016 12:00:00 EDT

Analgetic and Anxiolytic Effect of Preoperative Pregabalin

Conditions:   Intervertebral Disk Displacement;   Disk Prolapse
Interventions:   Drug: pregabalin;   Drug: Placebo;   Drug: morphine
Sponsor:   Asker & Baerum Hospital
Completed

Wed, 19 Jul 2006 12:00:00 EDT

Herb Drug Interaction of Traditional Chinese Herb and Commonly Used Drugs

Condition:   Healthy
Interventions:   Drug: Nalbuphine;   Drug: Morphine;   Drug: Morphine with Long dan xie gan tang;   Drug: Nalbuphine with Long dan xie gan tang;   Drug: Nubian with Long dan xie gan tang
Sponsor:   Tri-Service General Hospital
Unknown status

Thu, 18 Jun 2009 12:00:00 EDT

Postoperative Morphine Consumption After Caesarean Section- TAP Block vs Intracutaneous Infiltration

Condition:   Pregnancy
Interventions:   Procedure: TAP block;   Procedure: control
Sponsors:   St. Olavs Hospital;   Norwegian University of Science and Technology
Completed

Tue, 28 Aug 2012 12:00:00 EDT

Effectiveness of New Analgesic Strategy Compared to the Usal Antalgic Strategy

Condition:   Sickle Cell Anemia
Interventions:   Drug: Rapid optimized analgesic strategy;   Drug: current analgesic strategy
Sponsor:   Assistance Publique - Hôpitaux de Paris
Completed

Thu, 02 Apr 2009 12:00:00 EDT

Multimodal Analgesia in Cardiac Surgery (Pilot Study)

Condition:   Heart Diseases
Interventions:   Drug: Lidocaine;   Drug: Unrestricted Fentanyl;   Drug: Ketamine;   Drug: Precedex;   Drug: Duramorph
Sponsor:   Virginia Commonwealth University
Terminated

Tue, 12 Apr 2016 12:00:00 EDT

Patient-controlled Sedation With Propofol Versus Combined Sedation During Bronchoscopy

Condition:   Sedation, Bronchoscopy
Interventions:   Drug: Midazolam;   Drug: Propofol-Lipuro;   Drug: morphine-scopolamine;   Drug: Glycopyrrolate
Sponsor:   Lena Nilsson
Completed

Wed, 29 Nov 2017 12:00:00 EST

Lumbar Erector Spinae Plane Block for Back Surgery

Conditions:   Pain, Postoperative;   Anaesthesia;   Surgery;   Nerve Block;   Anesthesia, Local;   Back Pain;   Spinal Fusion
Interventions:   Procedure: Erector spinae plane block;   Drug: Levobupivacaine 0,25%;   Procedure: spine fusion;   Drug: NaCL 0,9%;   Drug: Sufentanil;   Drug: propofol;   Drug: Rocuronium Bromide;   Drug: sevoflurane;   Drug: paracetamol;   Drug: Ketorolac;   Drug: morphine pca;   Drug: Dexamethasone;   Drug: Morphine
Sponsor:   Dr M. B. Breebaart
Recruiting

Thu, 31 Jan 2019 12:00:00 EST

Effects of Anesthetic Technique on Immune and Inflammatory Systems Following Radical Prostatectomy

Condition:   Prostate Cancer
Interventions:   Drug: Patient controlled analgesia (PCA);   Drug: Thoracic Epidural Analgesia (TEA)
Sponsor:   Örebro University, Sweden
Completed

Tue, 07 Jun 2011 12:00:00 EDT

Multisystemic Therapy-Emerging Adults Trial

Condition:   Antisocial Behavior
Interventions:   Behavioral: Multisystemic Therapy for Emerging Adults;   Behavioral: Enhanced Treatment as Usual
Sponsors:   University of Massachusetts, Worcester;   National Institute of Mental Health (NIMH);   Oregon Social Learning Center;   Connecticut Department of Children and Families;   North American Family Institute;   Court Support Services Division;   Youth Villages
Active, not recruiting

Tue, 04 Oct 2016 12:00:00 EDT

An Extension of the TG1101-RMS201 Trial

Condition:   Relapsing Remitting Multiple Sclerosis
Intervention:   Biological: Ublituximab
Sponsor:   TG Therapeutics, Inc.
Active, not recruiting

Thu, 21 Dec 2017 12:00:00 EST

Morphine Consumption in Joint Replacement Patients, With or Without Gabapentin Treatment

Conditions:   Post Operative Pain;   Total Knee Replacement
Interventions:   Drug: Gabapentin;   Drug: Placebo
Sponsors:   McMaster University;   Hamilton Health Sciences Corporation
Completed

Wed, 02 Mar 2011 12:00:00 EST

A Clinical Study of SHR8554 Injection for the Treatment of Pain After Orthopedic Surgery

Condition:   Pain
Interventions:   Drug: SHR8554;   Drug: Saline Solution;   Drug: Morphine
Sponsor:   Jiangsu HengRui Medicine Co., Ltd.
Recruiting

Fri, 12 Mar 2021 12:00:00 EST

A Clinical Study of SHR8554 Injection for the Treatment of Pain After Abdominal Surgery.

Condition:   Pain
Interventions:   Drug: SHR8554 Injection;   Drug: Placebo;   Drug: Morphine
Sponsor:   Jiangsu HengRui Medicine Co., Ltd.
Enrolling by invitation

Tue, 23 Feb 2021 12:00:00 EST

Study of Evobrutinib in Participants With RMS

Condition:   Relapsing-remitting Multiple Sclerosis
Interventions:   Drug: Evobrutinib;   Drug: Avonex®;   Drug: Avonex® matched Placebo;   Drug: Evobrutinib matched Placebo
Sponsors:   EMD Serono Research & Development Institute, Inc.;   Merck KGaA, Darmstadt, Germany
Terminated

Thu, 25 Jul 2019 12:00:00 EDT

Using Mobile Technology to Enhance Multisystemic Therapy (MST) Outcomes

Condition:   Child Behavior Disorders
Intervention:   Device: VillageWhere App
Sponsors:   Evidence-Based Practice Institute, Seattle, WA;   National Institute of Mental Health (NIMH);   Medical University of South Carolina
Completed

Fri, 19 Dec 2014 12:00:00 EST

Connecting Women to Care: Home-based Psychotherapy for Women With MST Living in Rural Areas

Condition:   PTSD
Interventions:   Behavioral: STAIR;   Behavioral: PCT
Sponsors:   VA Office of Research and Development;   San Diego Veterans Healthcare System
Recruiting

Mon, 12 Feb 2018 12:00:00 EST

Magnesium Associated With Morphine for Cancer Pain Relief

Condition:   Cancer-related Problem/Condition
Intervention:   Drug: Magnesiun
Sponsor:   Federal University of São Paulo
Completed

Wed, 29 Feb 2012 12:00:00 EST

Effects of a Surgical Site Injection on Pain Scores and Narcotic Use After Orthopaedic Trauma Surgery

Condition:   Pertrochanteric Fracture
Interventions:   Drug: Marcaine, Duramorph , ketorolac;   Drug: Bupivacaine (Marcaine);   Drug: General Anesthetics
Sponsor:   NYU Langone Health
Completed

Wed, 03 Oct 2018 12:00:00 EDT

Evaluation of Maxillary and Mandibulary Nerve Blocks on Morphine Consumption

Condition:   Dento Facial Dysmorphism
Interventions:   Procedure: Maxillary and mandibular blocks;   Procedure: General anesthesia
Sponsor:   Hospices Civils de Lyon
Completed

Tue, 03 Oct 2017 12:00:00 EDT

The Effect of Intraoperative Dexmedetomidine on Postoperative Morphine Requirements After Breast Cancer Surgery

Condition:   Morphine Consumption
Interventions:   Drug: Dexmedetomidine;   Drug: placebo
Sponsor:   National Taiwan University Hospital
Not yet recruiting

Wed, 01 Jul 2020 12:00:00 EDT

FaR-RMS: An Overarching Study for Children and Adults With Frontline and Relapsed RhabdoMyoSarcoma

Condition:   Rhabdomyosarcoma
Interventions:   Drug: Irinotecan;   Drug: Actinomycin D;   Drug: Doxorubicin;   Drug: Ifosfamide;   Drug: Vincristine;   Drug: Vinorelbine;   Drug: Cyclophosphamide;   Drug: Temozolomide;   Radiation: radiotherapy
Sponsor:   University of Birmingham
Recruiting

Thu, 12 Nov 2020 12:00:00 EST

Dexmedetomidine as Adjuvant for FNB in TKA

Conditions:   Nerve Block;   Dexmedetomidine
Interventions:   Drug: Dexmedetomidine;   Procedure: ultrasound-guided femoral nerve block;   Device: intravenous patient-controlled analgesia pump with morphine;   Procedure: Continuous femoral nerve block
Sponsor:   First Affiliated Hospital, Sun Yat-Sen University
Completed

Wed, 05 Sep 2018 12:00:00 EDT

Effect of Gabapentin on Postoperative Morphine Consumption After Sleeve Gastrectomy

Condition:   Postoperative Complications
Interventions:   Drug: Gabapentin;   Drug: Placebo Oral Capsule
Sponsor:   King Saud University
Completed

Wed, 18 Jan 2017 12:00:00 EST

Assessing a Clinically-meaningful Opioid Withdrawal Phenotype

Conditions:   Opioid Withdrawal;   Opioid Use Disorder;   Opioid Craving
Interventions:   Drug: Morphine;   Drug: Naloxone + lofexidine pretreatment;   Drug: Naloxone + placebo pretreatment;   Drug: Lofexidine
Sponsors:   Johns Hopkins University;   National Institute on Drug Abuse (NIDA)
Not yet recruiting

Tue, 31 Aug 2021 12:00:00 EDT

Postoperative Pain and Morphine Consumption After Mastectomy - Lyrica

Condition:   Post-operative Pain
Intervention:   Drug: lyrica
Sponsors:   University of Texas Southwestern Medical Center;   Pfizer
Completed

Tue, 12 Jul 2011 12:00:00 EDT

Preoperative Methadone Single Dose Reduces Postoperative Morphine Consumption.

Condition:   Pain, Postoperative
Intervention:   Drug: Methadone
Sponsor:   Kantonsspital Baden
Completed

Fri, 18 May 2018 12:00:00 EDT

Interest of the Nefopam and PCA Morphine Combination for Postoperative Analgesia in Patients Undergoing Colon Surgery

Conditions:   Colonic Neoplasms;   Diverticulosis, Colonic
Interventions:   Drug: Nefopam;   Other: saline solution
Sponsor:   Centre Hospitalier Universitaire de Nīmes
Completed

Wed, 08 Aug 2018 12:00:00 EDT

Anti Emetic Efficacy of Combination of Ramosetron and Premixture of Naloxone With Patient-controlled Analgesia

Condition:   Postoperative Nausea and Vomiting
Interventions:   Drug: Ramosetron;   Drug: Naloxone;   Drug: saline;   Drug: Morphine
Sponsor:   Kyungpook National University Hospital
Completed

Tue, 14 Apr 2015 12:00:00 EDT

A Study of Suboptimally Controlled Participants Previously Taking Injectable DMDs for RMS (CLICK-MS)

Condition:   Multiple Sclerosis
Intervention:   Drug: Cladribine Tablets
Sponsors:   EMD Serono Research & Development Institute, Inc.;   Merck KGaA, Darmstadt, Germany
Recruiting

Wed, 01 May 2019 12:00:00 EDT

Morphine COnsumption in Joint Replacement Patients, With and Without GaBapentin Treatment, a RandomIzed ControlLEd Study

Conditions:   Postoperative Pain;   Total Hip Replacement
Interventions:   Drug: Gabapentin;   Other: Placebo
Sponsor:   Hamilton Health Sciences Corporation
Completed

Tue, 28 Apr 2009 12:00:00 EDT

Multimodal Analgesic Using Morphine and COX-2 With or Without Dexmedetomidine for Colorectal Surgery

Condition:   Pain, Postoperative
Interventions:   Drug: Dexmedetomidine;   Drug: Normal Saline
Sponsor:   The University of Hong Kong
Completed

Fri, 13 May 2011 12:00:00 EDT

A Study of Suboptimally Controlled Participants Previously Taking Oral or Infusion DMDs for RMS (MASTER-2)

Condition:   Multiple Sclerosis
Intervention:   Drug: Cladribine Tablets
Sponsors:   EMD Serono Research & Development Institute, Inc.;   Merck KGaA, Darmstadt, Germany
Recruiting

Wed, 01 May 2019 12:00:00 EDT

Impact of a Strategy Combining Morphine Savings and Anesthesia Technique on the Quality of Post-operative Rehabilitation

Condition:   Cesarean Section Complications
Intervention:  
Sponsor:   Centre Hospitalier Régional Metz-Thionville
Recruiting

Thu, 07 May 2020 12:00:00 EDT

Evaluation of the Analgesia Nociception Index and Videopupillometry to Predict a Child's Post-tonsillectomy Morphine Prescription

Condition:   Pain, Postoperative
Intervention:   Other: Nerve stimulation of the ulnar nerve
Sponsor:   University Hospital, Limoges
Completed

Tue, 09 Oct 2018 12:00:00 EDT

Ketamine Combination With Spinal Morphine for Post Thoracic Surgery Pain : A Randomized Control Study

Conditions:   Pain;   Postoperative Period
Interventions:   Other: NSS;   Drug: Ketamine
Sponsor:   Mahidol University
Completed

Wed, 07 Oct 2015 12:00:00 EDT

Photobiomodulation Therapy in Exercise Capacity Assessed by 6MST in Patients With COPD

Condition:   Chronic Obstructive Pulmonary Disease (COPD
Intervention:   Device: Photobiomodulation Therapy (PBMT)
Sponsor:   University of Nove de Julho
Completed

Tue, 21 Aug 2018 12:00:00 EDT

SWC on aEEG in Post-surgical Neonates on Morphine and Midazolam

Conditions:   Neurology;   Newborn;   Analgesia;   Sedation;   Surgery
Intervention:  
Sponsor:   Royal Children's Hospital
Completed

Thu, 30 Sep 2010 12:00:00 EDT

Effect of Intraoperative IV Ketamine on Postoperative Morphine Consumption During Intestinal Surgery

Condition:   Postoperative Analgesia
Interventions:   Drug: Ketamine Hydrochloride;   Drug: Normal saline
Sponsor:   Assiut University
Unknown status

Fri, 17 Nov 2017 12:00:00 EST

Relation of Obesity With Frequency of Meals (MST 0557)

Conditions:   Obesity;   Insulin Resistance;   Fatty Liver
Interventions:   Other: high frequency of meals;   Other: twice a day meals
Sponsors:   Rockefeller University;   Cornell University
Completed

Thu, 29 Sep 2005 12:00:00 EDT

Low-level Laser Acupuncture Reduces Postoperative Pain and Morphine-related Side Effects in Patients With Total Knee Arthroplasty:

Condition:   Low-level Laser Acupuncture in Patients With Total Knee Arthroplasty
Interventions:   Device: low-level laser;   Device: Sham laser
Sponsor:   Taipei Veterans General Hospital, Taiwan
Completed

Mon, 24 Jun 2019 12:00:00 EDT

Vancomycin Associated Red Man Syndrome (RMS)

Condition:   Red Man Syndrome
Intervention:  
Sponsors:   Children's Mercy Hospital Kansas City;   Katherine Berry Richardson Foundation
Completed

Fri, 16 Jan 2009 12:00:00 EST

The Standard Concentration of Morphine as a Positive Control for Intradermal Skin Test

Condition:   Intradermal Test
Intervention:  
Sponsor:   Chulalongkorn University
Completed

Mon, 02 Mar 2009 12:00:00 EST

Adductor Canal Block With Continuous Infusion Versus Intermittent Boluses and Morphine Consumption

Condition:   Postoperative Pain
Intervention:   Drug: ropivacaine 0.2%
Sponsors:   Pia Jaeger;   University of California, San Diego;   Bispebjerg Hospital;   Smiths Medical, ASD, Inc.
Completed

Thu, 03 Sep 2015 12:00:00 EDT

Celecoxib for Reducing Morphine Requirement After Thyroid Surgery: A Randomized Controlled Trial

Conditions:   Postoperative Pain;   Thyroidectomy;   Cyclooxygenase 2 Inhibitors
Intervention:   Drug: celecoxib
Sponsor:   Mahidol University
Completed

Fri, 24 Aug 2007 12:00:00 EDT

Evaluation of the Relationship Between ABCG2 Mutation and Teriflunomide Exposure and Safety in Chinese RMS Patients Treated With Teriflunomide 14 mg Once Daily for 24 Weeks

Condition:   Multiple Sclerosis
Intervention:   Drug: TERIFLUNOMIDE
Sponsor:   Sanofi
Completed

Mon, 01 Jun 2020 12:00:00 EDT

Methylnaltrexone as a Method to Improve Ticagrelor Uptake in Morphine Treated STEMI Patients

Conditions:   STEMI;   Morphine;   Ticagrelor;   Methylnaltrexone
Interventions:   Drug: Methylnaltrexone bromide (Relistor®).;   Drug: Sodium Chloride 9mg/mL
Sponsor:   Karolinska University Hospital
Completed

Mon, 24 Oct 2016 12:00:00 EDT

Programmed Intermittent Bolus Versus Continuous Infusion for Epidural Analgesia in Abdominal Surgery

Conditions:   Analgesia, Epidural;   Pain, Postoperative
Interventions:   Device: Programmed intermittent epidural bolus (PIEB) of bupicavaine;   Device: Continuous epidural infusion (CEI) of bupivacaine;   Device: Continuous epidural infusion (CEI) of morphine
Sponsor:   CHU de Quebec-Universite Laval
Completed

Wed, 05 Feb 2020 12:00:00 EST

Efficacy and Safety of Q8003 in the Management of Post-bunionectomy Pain

Condition:   Postoperative Pain
Interventions:   Drug: Q8003 (morphine sulfate and oxycodone hydrochloride);   Drug: Placebo
Sponsor:   QRxPharma Inc.
Completed

Mon, 19 Nov 2007 12:00:00 EST

SMART Design to Compare Antipsychotic Treatments in Treatment-Resistant Schizophrenia

Condition:   Treatment-resistant Schizophrenia
Interventions:   Drug: Clozapine;   Device: MECT;   Device: DBS
Sponsor:   Shanghai Mental Health Center
Not yet recruiting

Thu, 27 Aug 2020 12:00:00 EDT

The Efficacy of Adductor-Canal-Blockade on Pain and Morphine Consumption After Total Knee Arthroplasty

Conditions:   Postoperative Pain;   Knee Arthroplasty
Interventions:   Procedure: Adductor-Canal-Blockade with Ropivacaine;   Procedure: Adductor-Canal-blockade with saline
Sponsor:   Rigshospitalet, Denmark
Completed

Fri, 17 Dec 2010 12:00:00 EST

Use of Virtual Reality to Reduce Morphine Consumption in Adolescents Undergoing Scoliosis Surgery

Condition:   Scoliosis
Interventions:   Device: Virtual Reality (VR) technique;   Drug: Analgesic protocol
Sponsor:   University Hospital, Toulouse
Not yet recruiting

Wed, 19 May 2021 12:00:00 EDT

An Open-label Study Evaluating Ofatumumab Treatment Effectiveness and PROs in Subjects With RMS Transitioning From Dimethyl Fumarate or Fingolimod to Ofatumumab

Condition:   Relapsing Multiple Sclerosis
Intervention:   Biological: Ofatumumab
Sponsor:   Novartis Pharmaceuticals
Recruiting

Mon, 20 Apr 2020 12:00:00 EDT

Intraarticular Analgesia After Total Hip Arthroplasty, a Randomised Study

Condition:   Arthroplasty, Replacement, Hip
Interventions:   Drug: Epidural Ropivacaine, morphine;   Drug: Ropivacaine, Ketorolac and Adrenaline
Sponsor:   University of Aarhus
Completed

Thu, 09 Feb 2006 12:00:00 EST

The Efficacy of Adductor-Canal-Blockade on Pain and Morphine Consumption After Revision Knee Arthroplasty

Conditions:   Postoperative Pain;   Knee Arthroplasty
Interventions:   Procedure: Adductor-Canal-Blockade with Ropivacaine;   Procedure: Adductor-Canal-blockade with saline
Sponsor:   Rigshospitalet, Denmark
Completed

Tue, 31 Aug 2010 12:00:00 EDT

Comparison of Different Methods of Pain Control After Cesarean Section for Patients on Buprenorphine or Methadone

Condition:   Caesarean Delivery
Interventions:   Drug: TAP Block;   Drug: Ropivacaine;   Drug: Acetaminophen;   Drug: Morphine
Sponsors:   Dartmouth-Hitchcock Medical Center;   Massachusetts General Hospital;   Brigham and Women's Hospital
Withdrawn

Wed, 19 Mar 2014 12:00:00 EDT

Continuous Wound Catheter Analgesia Associated With Intravenous Morphine PCA After Thoracotomy

Conditions:   Pain;   Thoracotomy
Interventions:   Drug: ropivacaine 0.75% - device : wound catheter Silver™ 19 cm and Easypump™ 400 mL (BBraun);   Drug: Placebo;   Drug: ropivacaine 0.2% - device : wound catheter Silver™ 19 cm and Easypump™ 400 mL (BBraun)
Sponsor:   University Hospital, Strasbourg, France
Completed

Tue, 02 Oct 2012 12:00:00 EDT

A 12 Week Randomized Open Label Parallel Group Multicenter Study to Evaluate Bioequivalence of 20 mg Subcutaneous Ofatumumab Injected by Pre-filled Syringe or Autoinjector in Adult RMS Patients

Condition:   Multiple Sclerosis
Interventions:   Combination Product: ofatumumab with PRF;   Combination Product: ofatumumab with AI
Sponsor:   Novartis Pharmaceuticals
Completed

Mon, 18 Jun 2018 12:00:00 EDT

The Effect of Intraoperative Nefopam, Ketoprofen and Paracetamol Combination vs Ketoprofen and Paracetamol Combination on Postoperative Morphine Requirements After Laparoscopic Cholecystectomy: A Randomized, Controlled Trial

Conditions:   Cholecystectomy;   Pain, Postoperative;   Opioid Use
Interventions:   Drug: nefopam, ketoprofen, paracetamol;   Drug: saline infusion, ketoprofen, paracetamol
Sponsor:   American University of Beirut Medical Center
Recruiting

Tue, 10 Nov 2020 12:00:00 EST

The Efficacy of Adductor-Canal-Blockade on Morphine Consumption, Pain and Mobilisation After Total Knee Arthroplasty

Condition:   Total Knee Arthroplasty
Interventions:   Procedure: Adductor-Canal-Blockade;   Procedure: Adductor-Canal-blockade with saline
Sponsor:   Rigshospitalet, Denmark
Completed

Fri, 16 Apr 2010 12:00:00 EDT

Using Patient Reported Outcomes (PROs) to Evaluate Teriflunomide Treatment in Relapsing Multiple Sclerosis (RMS) Patients

Condition:   Multiple Sclerosis
Intervention:   Drug: Teriflunomide
Sponsor:   Sanofi
Completed

Wed, 10 Jul 2013 12:00:00 EDT

Morphine-Sparing Effect And Safety Of Parecoxib Administered Intravenously For The Treatment Of Postoperative Pain

Condition:   Pain, Postoperative
Intervention:   Drug: Parecoxib and placebo
Sponsor:   Pfizer
Completed

Fri, 02 Sep 2005 12:00:00 EDT

Impact of Disease Modifying Therapies (DMTs) and Associated Support Services in Relapsing Multiple Sclerosis (RMS) Patients

Condition:   Relapsing Multiple Sclerosis
Interventions:   Drug: Rebif;   Other: Other: Disease modifying therapies (DMT)
Sponsors:   Merck KGaA, Darmstadt, Germany;   Merck Serono Limited, UK
Completed

Thu, 17 May 2012 12:00:00 EDT

Etoricoxib With Flavoxate for Reducing Morphine Requirement After Transurethral Prostatectomy (TURP)

Condition:   Pain
Interventions:   Drug: etoricoxib;   Drug: flavoxate;   Drug: etoricoxib, flavoxate;   Drug: placebo
Sponsor:   Mahidol University
Completed

Tue, 27 Feb 2007 12:00:00 EST

Hydroxyzine for the Prevention of Pruritus From Spinal Morphine in Transabdominal Hysterectomy Patients

Conditions:   Pruritus;   Nausea;   Vomiting
Intervention:   Drug: hydroxyzine
Sponsor:   Mahidol University
Completed

Mon, 25 Jan 2010 12:00:00 EST

Influence of Intraoperative Analgesia on the Postoperative Morphine Consumption

Condition:   Anesthesia
Interventions:   Drug: Remifentanil;   Drug: Sufentanil
Sponsor:   Hopital Foch
Completed

Wed, 15 Oct 2008 12:00:00 EDT

Effects of Perioperative B&O Suppositories on Post-op Pain and Morphine Use After Laparoscopic Prostatectomy

Condition:   Pain
Intervention:   Drug: belladonna 16.2 mg and opium 60 mg suppository
Sponsors:   Benaroya Research Institute;   Virginia Mason Hospital/Medical Center
Completed

Wed, 18 Mar 2009 12:00:00 EDT

Effect of Combinations of Paracetamol, Ibuprofen, and Dexamethasone on Patient-Controlled Morphine Consumption in the First 24 Hours After Total Hip Arthroplasty

Conditions:   Pain, Acute;   Hip Arthropathy;   Analgesia;   Postoperative Pain
Interventions:   Drug: Paracetamol;   Drug: Ibuprofen (400 mg x 4);   Drug: Dexamethasone;   Drug: Placebo oral tablet (x 4);   Drug: Placebo IV (x 1)
Sponsor:   Naestved Hospital
Recruiting

Fri, 11 Oct 2019 12:00:00 EDT

The Use of Low Dose Prophylactic Naloxone Infusion to Prevent Respiratory Depression With Intrathecal Morphine.

Condition:   Respiratory Depression
Interventions:   Drug: Naloxone;   Drug: Placebo
Sponsor:   University College Dublin
Completed

Thu, 01 Sep 2016 12:00:00 EDT

Study to Explore Effectiveness of Sublingual Fentanyl Spray in Emergency Department Patients With Acute Pain

Condition:   Acute Pain
Interventions:   Drug: Morphine 6 mg;   Drug: Fentanyl 100 µg;   Drug: Fentanyl 200 µg;   Drug: Fentanyl 400 µg;   Drug: Placebo Sublingual Spray;   Drug: Intravenous Placebo
Sponsor:   INSYS Therapeutics Inc
Withdrawn

Wed, 14 May 2014 12:00:00 EDT

Optimizing Outpatient Anesthesia (OSPREy-Outpatient Surgery Pain Relief Enhancement)

Conditions:   Opioid Use;   Pain, Postoperative
Interventions:   Drug: Methadone;   Drug: Fentanyl;   Drug: Hydromorphone;   Drug: Morphine;   Drug: Sufentanil
Sponsors:   Duke University;   National Institute on Drug Abuse (NIDA)
Recruiting

Wed, 31 Oct 2018 12:00:00 EDT

Nefopam and Morphine Consumption in the Treatment of Ureteral Calculi

Condition:   Ureteral Calculi, Hyperalgic, Not Complicated
Intervention:   Drug: Néfopam
Sponsor:   University Hospital, Clermont-Ferrand
Completed

Thu, 20 Mar 2008 12:00:00 EDT

Reduction of Bladder Injection Pain With Belladonna Opiate Suppository

Conditions:   Overactive Bladder;   Urinary Urge Incontinence;   Urinary Bladder, Neurogenic;   Painful Bladder Syndrome
Interventions:   Drug: Onabotulinumtoxin A (BoNT);   Drug: belladonna;   Drug: Morphine;   Drug: Placebo;   Drug: Active B&O suppository of belladonna
Sponsor:   Edgar LeClaire, MD
Completed

Mon, 09 Nov 2015 12:00:00 EST

Adductor Canal Nerve Block Following Total Knee Arthroplasty

Condition:   Post-op Pain
Interventions:   Drug: Morphine PCA started at the end of surgery, 1 Percocet 1/325mg every 4 hours; may receive a second Percocet if needed.;   Drug: For the 30ml ropivacaine the intervention would be the subject can request extra pain medication which would be Percocet and/or morphine PCA.
Sponsor:   Loma Linda University
Withdrawn

Wed, 11 Sep 2013 12:00:00 EDT

5HT3 Antagonists to Treat Opioid Withdrawal and to Prevent the Progression of Physical Dependence

Conditions:   Opioid Withdrawal;   Physical Dependence
Interventions:   Drug: Ondansetron;   Drug: Placebo;   Drug: Morphine;   Drug: Naloxone 0.4 mg/70 kg;   Drug: Naloxone 0.8 mg/70 kg
Sponsors:   Stanford University;   National Institute on Drug Abuse (NIDA)
Completed

Fri, 09 Mar 2012 12:00:00 EST

Recommendations of Enhanced Recovery Interventions for Patient's Clinical Team and Collection of Associated Data

Condition:   Perioperative Optimization
Interventions:   Dietary Supplement: Gatorade ®;   Dietary Supplement: Clearfast ®;   Drug: Preoperative Gabapentin;   Drug: Neuraxial Morphine Injection;   Drug: Regional Technique Analgesia;   Drug: Perphenazine;   Drug: Aprepitant;   Drug: Totally intravenous Anesthesia (TIVA);   Other: Stroke volume comparator;   Other: Fluid Therapy;   Drug: Ketamine;   Drug: Lidocaine;   Drug: Intraoperative opioids;   Drug: Primary Anesthetic Spinal;   Drug: Primary Anesthetic Volatile Agent;   Drug: Postoperative Gabapentin
Sponsors:   Jennifer Holder-Murray;   Berry Consultants
Not yet recruiting

Wed, 28 Oct 2020 12:00:00 EDT

Comparison of the Efficacy of Ketamine in Pediatric Patients With Idiopathic Scoliosis After Surgery

Condition:   Progressive Infantile Idiopathic Scoliosis
Interventions:   Drug: Ketamine Hydrochloride;   Other: Placebo;   Drug: Remifentanil;   Drug: Morphine hydrochloride
Sponsors:   Fundació Sant Joan de Déu;   Instituto de Salud Carlos III
Completed

Thu, 08 Oct 2015 12:00:00 EDT

Study to Explore the Mechanism of Action of Ocrelizumab and B-Cell Biology in Participants With Relapsing Multiple Sclerosis (RMS) or Primary Progressive Multiple Sclerosis (PPMS)

Conditions:   Relapsing Multiple Sclerorsis;   Multiple Sclerosis, Primary Progressive
Interventions:   Drug: Ocrelizumab;   Procedure: Lumbar Puncture;   Drug: Methyloprednisolone;   Drug: Antihistamine
Sponsor:   Genentech, Inc.
Active, not recruiting

Tue, 23 Feb 2016 12:00:00 EST

Different Approaches to Maternal Hypotension During Cesarean Section

Conditions:   Pregnancy;   Cesarean Section;   Anesthesia,Spinal;   Hypotension
Interventions:   Drug: Bupivacaine;   Drug: Morphine;   Drug: Lactated Ringer's solution;   Drug: Ephedrine, continuous infusion;   Drug: Ephedrine, bolus;   Drug: Atropine
Sponsors:   University of Parma;   Azienda Ospedaliero-Universitaria di Parma
Completed

Thu, 08 Oct 2009 12:00:00 EDT


Prospective Study About Clinical and Pharmacogenetic Safety of Opioid Use for Chronic Pain

Condition:   Chronic Pain
Interventions:   Drug: Morphine;   Drug: Oxycodone;   Drug: Fentanyl;   Drug: Buprenorphine
Sponsors:   IRCCS Policlinico S. Matteo;   University of Pavia
Suspended

Wed, 10 Jun 2009 12:00:00 EDT

Liposomal Bupivacaine in Implant Based Breast Reconstruction

Conditions:   Breast Cancer;   Postoperative Pain
Interventions:   Drug: Liposomal bupivacaine;   Drug: Bupivacaine with epinephrine;   Drug: Morphine sulfate;   Drug: Hydrocodone/acetaminophen;   Drug: Diazepam
Sponsor:   Loma Linda University
Terminated

Wed, 20 Jan 2016 12:00:00 EST

Pain Relief for Ventilated Patients With Multiple Rib Fractures Using the ON-Q Pain Relief System

Condition:   Rib Fractures
Interventions:   Device: ON-Q bupivicaine administration;   Drug: IV opioid administration
Sponsor:   The Cooper Health System
Terminated

Mon, 13 Apr 2009 12:00:00 EDT

Comparison of Treatment by IM Ketamine to IV Ketamine in Patients With Renal Colic

Conditions:   Acute Pain;   Renal Colic
Interventions:   Drug: IV Ketamine;   Drug: IM Ketamine
Sponsor:   Tel-Aviv Sourasky Medical Center
Unknown status

Wed, 10 Jul 2019 12:00:00 EDT

is There an Alternative to Ultrasound Guided Interscalene Block?

Conditions:   Regional Anesthesia;   Interscalene Block;   Shoulder Surgery
Interventions:   Drug: bupivacaine;   Device: ultrasound;   Drug: morphine
Sponsor:   Tunisian Military Hospital
Unknown status

Tue, 24 Mar 2015 12:00:00 EDT

Hypothermia's Impact on Pharmacology

Conditions:   Cardiac Arrest;   Hypothermia
Intervention:  
Sponsor:   Children's Hospital of Philadelphia
Completed

Thu, 22 Mar 2012 12:00:00 EDT

HLA-mismatched MST vs HLA-matched NST for AML in Intermediate-risk

Condition:   Acute Myeloid Leukemia
Interventions:   Genetic: HLA mismatched stem cell;   Genetic: HLA matched stem cell;   Drug: cyclosporine A;   Drug: Mycophenolate mofetil;   Drug: Ara-C;   Drug: fludarabine;   Drug: anti-lymphocyte globulin;   Drug: cyclophosphamide
Sponsor:   The Affiliated Hospital of the Chinese Academy of Military Medical Sciences
Completed

Wed, 03 Jun 2015 12:00:00 EDT

Study of Buprenorphine Sublingual Spray Versus Standard of Care Narcotic Therapy for the Treatment of Post-Operative Pain

Condition:   Pain, Postoperative
Interventions:   Drug: Buprenorphine Sublingual Spray;   Drug: Morphine;   Drug: Oxycodone Hydrochloride;   Drug: Zofran
Sponsor:   INSYS Therapeutics Inc
Completed

Fri, 18 Aug 2017 12:00:00 EDT

Perioperative Use of Gabapentin To Decrease Narcotic Requirements in Spinal Fusion

Condition:   Postoperative Pain
Interventions:   Drug: Gabapentin;   Drug: Placebo;   Drug: Morphine
Sponsors:   Medical College of Wisconsin;   Children's Hospital and Health System Foundation, Wisconsin
Completed

Fri, 01 Aug 2008 12:00:00 EDT

Evaluation of the Roll of IV Fluids in the Treatment of Renal Colic

Condition:   Renal Colic
Interventions:   Drug: 0.9% Sodium-chloride;   Drug: Placebos;   Drug: Optalgin, Voltaren, Morphine
Sponsor:   Sheba Medical Center
Withdrawn

Fri, 18 May 2018 12:00:00 EDT

Effect of Midazolam on Inflammatory Response and Organ Function in Mechanically Ventilated Sepsis Patients With Different Immune Status

Conditions:   Inflammatory Disorder of Immune System;   Sepsis
Interventions:   Other: blood sample collection;   Drug: Midazolam;   Drug: Morphine;   Procedure: Sedation interruption
Sponsor:   Xiangya Hospital of Central South University
Unknown status

Fri, 09 May 2014 12:00:00 EDT

Patient Controlled Intrathecal Analgesia With Bupivacaine for Chronic Low Back Pain

Conditions:   Pain, Intractable;   Breakthrough Pain;   Chronic Pain
Interventions:   Drug: Bupivacaine;   Drug: Opioid
Sponsor:   University Hospitals Cleveland Medical Center
Completed

Thu, 01 Sep 2016 12:00:00 EDT

Intravenous Paracetamol for Postoperative Pain

Conditions:   Pain, Postoperative;   Recovery of Function;   Child
Interventions:   Drug: Paracetamol;   Drug: Placebo (for paracetamol);   Drug: Ketoprofen;   Drug: Tramadol;   Drug: Morphine
Sponsor:   Lithuanian University of Health Sciences
Completed

Thu, 25 Sep 2014 12:00:00 EDT

Efficacy of Intramuscular Naloxone 0.4mg. in Prophylaxis of Intrathecal Morphine Induced Pruritus After Cesarean Section

Condition:   Morphine Adverse Reaction
Interventions:   Drug: naloxone;   Drug: normal saline
Sponsor:   Mahidol University
Completed

Thu, 30 Apr 2009 12:00:00 EDT

Role of Multimodal Analgesia in Decreasing Perioperative Pain in Tibial Plateau Fractures

Condition:   Tibial Plateau Fractures
Interventions:   Drug: Injection;   Drug: Injections
Sponsor:   University of Utah
Enrolling by invitation

Wed, 08 Sep 2021 12:00:00 EDT

Effectiveness of Rebif® in Clinically Isolated Syndrome and Relapsing Multiple Sclerosis Using RebiSmart™

Conditions:   Relapsing Multiple Sclerosis;   Clinically Isolated Syndrome
Intervention:   Drug: Rebif
Sponsors:   Merck KGaA, Darmstadt, Germany;   Merck Romania SRL, an affiliate of Merck KGaA, Darmstadt, Germany
Completed

Wed, 01 Oct 2014 12:00:00 EDT

Perineural Low-dose Dexamethasone Added to Infraclavicular Block Anesthesia

Condition:   Postoperative Pain
Interventions:   Drug: Dexamethasone;   Drug: Ropivacaine;   Drug: Paracetamol;   Drug: Morphine;   Drug: Lidocaine
Sponsor:   Foisor Orthopedics Clinical Hospital
Completed

Fri, 04 Mar 2016 12:00:00 EST

NALDEBAIN for Postoperative Pain Management in Take Down of Anastomosis

Condition:   Postoperative Pain
Interventions:   Drug: Naldebain;   Drug: Morpine
Sponsor:   China Medical University Hospital
Unknown status

Tue, 26 Feb 2019 12:00:00 EST

A Study to Evaluate the Efficacy and Safety of Tapentadol (CG5503) in the Treatment of Acute Pain After Abdominal Hysterectomy

Conditions:   Hysterectomy;   Postoperative
Interventions:   Drug: Morphine;   Drug: CG5503 IR;   Drug: Placebo
Sponsors:   Grünenthal GmbH;   Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Completed

Thu, 24 May 2007 12:00:00 EDT

Neurostimulation for the Treatment of Post-Operative Ileus

Condition:   Ileus
Intervention:   Device: ElectroCore RMS-1100 Resolution Motility System™
Sponsor:   ElectroCore INC
Withdrawn

Mon, 02 Mar 2009 12:00:00 EST

BIOSOLVE-IV Magmaris Swiss Satellite Registry

Condition:   Coronary Artery Disease
Intervention:   Device: Magmaris Resorbable Magnesium Scaffold (RMS)
Sponsor:   University Hospital, Geneva
Recruiting

Fri, 19 Jul 2019 12:00:00 EDT

Treatment Adherence When Using RebiSmart™ in Relapsing Multiple Sclerosis Subjects

Conditions:   Multiple Sclerosis;   MS
Intervention:   Device: RebiSmart™
Sponsors:   Merck KGaA, Darmstadt, Germany;   EMD Inc., Canada
Completed

Fri, 21 May 2010 12:00:00 EDT

OSA Screen Negative With Spinal Duramorph

Condition:   Respiratory Depression
Intervention:   Device: Capnography monitoring
Sponsor:   Wake Forest University Health Sciences
Terminated

Fri, 12 May 2017 12:00:00 EDT

Perineural Dexamethasone in Femural Nerve Block After Ligament Reconstruction

Condition:   Postoperative Pain
Interventions:   Drug: Dexamethasone phosphate;   Drug: Paracetamol;   Drug: Morphine;   Drug: Lidocaine;   Drug: Ropivacaine
Sponsor:   Foisor Orthopedics Clinical Hospital
Completed

Fri, 22 Apr 2016 12:00:00 EDT

Estimation of the ED95 of Intrathecal Hyperbaric Prilocaine 2% With Sufentanyl for Scheduled Cesarean Delivery

Condition:   Pregnant Women
Interventions:   Drug: HB Prilocaine 2% (varying dose);   Drug: HB Prilocaine 2%;   Drug: Sufentanil;   Drug: Morphine
Sponsor:   Centre Hospitalier Universitaire Saint Pierre
Completed

Mon, 30 Jan 2017 12:00:00 EST

Low Dose Ketamine Infusion for Postoperative Analgesia After Total Knee Arthroplasty

Condition:   Postoperative Pain
Intervention:  
Sponsor:   Mustafa Kemal University
Completed

Wed, 11 Sep 2019 12:00:00 EDT

Safety and Efficacy of Cocktail Periarticular Injection in Simultaneous Total Knee Arthroplasty

Condition:   Pain, Postoperative
Intervention:   Drug: ropivacaine, fentanyl, adrenaline
Sponsor:   Peking Union Medical College Hospital
Completed

Tue, 21 Oct 2014 12:00:00 EDT

Comparison of Butorphanol and Tramadol Associated Patient-Controlled Analgesia (PCA) After Hysterectomy

Conditions:   Postoperative Pain;   Hysterectomy
Interventions:   Drug: Saline;   Drug: Butorphanol tartrate;   Drug: Tramadol Hydrochloride
Sponsors:   Nanjing Medical University;   HRSA/Maternal and Child Health Bureau
Completed

Thu, 02 Aug 2007 12:00:00 EDT

Evaluation of Non-opioid Balanced General Anesthesia in Cardiac Surgery With Extracorporeal Circulation: a Randomized, Controlled, Multicenter Superiority Trial

Conditions:   Opioid-free Anesthesia;   Cardiac Surgery
Interventions:   Drug: Balanced general anesthesia without morphine;   Drug: Standard general anesthesia balanced with morphine;   Other: Data collection;   Other: Assessment of pain;   Other: Recovery quality score
Sponsor:   Centre Hospitalier Universitaire Dijon
Recruiting

Fri, 14 May 2021 12:00:00 EDT

Nerve Block Versus Non-targeted Local Anaesthesia in Breast Surgery

Condition:   Pain, Post Operative
Interventions:   Other: targeted chirocaine pec block;   Other: standard chirocaine infiltration;   Other: standard post-operative analgesia
Sponsor:   BMI Healthcare
Unknown status

Wed, 08 Apr 2015 12:00:00 EDT

Pain in Patients With Dementia and Behavioural Disturbances

Conditions:   Dementia;   Pain;   Agitation
Interventions:   Drug: Paracetamol;   Drug: Morphine;   Drug: Buprenorphine plaster;   Drug: Pregabalin
Sponsors:   University of Bergen;   The Research Council of Norway
Completed

Mon, 30 Nov 2009 12:00:00 EST

Perioperative Analgesia for Knee Arthroplasty (PAKA)

Condition:   Knee Arthritis
Interventions:   Drug: Femoral Nerve Block;   Drug: peri-articular infiltration
Sponsor:   University of Warwick
Completed

Thu, 22 Mar 2012 12:00:00 EDT

Multistimulation Group Therapy for Alzheimer's Disease

Condition:   Alzheimer's Disease
Intervention:   Other: Multidimensional stimulation group therapy
Sponsor:   Fondazione Don Carlo Gnocchi Onlus
Completed

Tue, 09 Jul 2013 12:00:00 EDT

Berlin Magnetic Seizure Therapy Depression Trial 01

Conditions:   Unipolar Depression;   Bipolar Depression
Intervention:   Procedure: magnetic seizure therapy
Sponsor:   Charite University, Berlin, Germany
Completed

Fri, 05 Jun 2009 12:00:00 EDT

Opioid Receptors Influence Ischemia-Reperfusion Injury

Condition:   Ischemia-Reperfusion Injury
Interventions:   Drug: morphine;   Drug: naloxone;   Drug: Technetium-TC99m-labeled Annexin A5;   Procedure: forearm ischemic exercise;   Procedure: ten minute forearm ischemia
Sponsor:   Radboud University
Suspended

Fri, 16 Sep 2005 12:00:00 EDT

Cognitive Function and Addiction Under Opioid Tapering

Conditions:   Chronic Pain;   Opioid Use
Interventions:   Drug: Opioids taper off;   Drug: Opioid stable treatment
Sponsors:   Rigshospitalet, Denmark;   The Ministry of Science, Technology and Innovation, Denmark;   Hørslev-Fonden
Completed

Thu, 07 Dec 2017 12:00:00 EST

Opioid-Free Anesthetic for Tonsillectomy

Conditions:   Anesthesia;   Opioid Use;   Tonsillitis;   Sleep Disorder;   Surgery
Interventions:   Drug: Ketorolac;   Drug: Dexmedetomidine;   Drug: Morphine;   Drug: Fentanyl
Sponsors:   Children's Hospital of Philadelphia;   University of Pennsylvania;   University of Tennessee Health Science Center
Recruiting

Thu, 27 Aug 2020 12:00:00 EDT

The Effect of Dexamethasone in Combination With Paracetamol and Ibuprofen on Postoperative Pain After Spine Surgery

Condition:   Pain
Interventions:   Drug: Dexamethasone;   Other: Placebo;   Drug: Morphine;   Drug: Zofran;   Drug: Paracetamol;   Drug: Ibuprofen
Sponsors:   Rigshospitalet, Denmark;   Glostrup University Hospital, Copenhagen
Completed

Tue, 01 Oct 2013 12:00:00 EDT

Tramadol to Reduce Opioid Withdrawal Symptoms

Condition:   Opioid-Related Disorders
Interventions:   Drug: Tramadol;   Drug: Naloxone;   Drug: Morphine
Sponsor:   National Institute on Drug Abuse (NIDA)
Completed

Fri, 02 Sep 2005 12:00:00 EDT

Parent Nurse Controlled Analgesic in Pediatric Patients With Developmental Delay

Condition:   Post Operative Pain
Interventions:   Other: Pain and standard side effect management for PNCA with basal method.;   Other: Pain and standard side effect management with PNCA without basal;   Other: Pain and standard side effect management with IV on an as needed basis method.
Sponsors:   Medical College of Wisconsin;   Children's Hospital and Health System Foundation, Wisconsin
Completed

Fri, 29 Aug 2008 12:00:00 EDT

Local Multimodal Injection Versus Regional Anesthesia in Controlling Pain for Treating Rotational Ankle Fractures

Condition:   Ankle Fractures
Interventions:   Drug: Regional anesthesia group;   Drug: Local multimodal analgesia group
Sponsor:   University of Utah
Enrolling by invitation

Wed, 25 Aug 2021 12:00:00 EDT

Effectiveness of Analgesia in Total Knee Arthroplasty

Condition:   Pain
Interventions:   Drug: several drugs: morphine chloride,ropivacaine,epinephrine,ketorolac;   Drug: ropivacaine,morphine chloride,epinephrine,ketorolac;   Drug: ropivacaine;   Drug: morphine ,ketorolac
Sponsor:   Jose Antonio Bernia Gil
Completed

Fri, 25 Feb 2011 12:00:00 EST

Granisetron vs Granisetron and Dexamethasone on the Reduction of Postoperative Nausea and Vomiting

Condition:   PONV
Interventions:   Drug: Granisetron 1 Mg/mL Intravenous Solution And Dexamethasone 4mg;   Drug: Granisetron 1 Mg/mL Intravenous Solution
Sponsor:   Universiti Sains Malaysia
Recruiting

Wed, 30 Sep 2020 12:00:00 EDT

Study to Evaluate the Efficacy, Safety and Tolerability of N1539

Condition:   Hysterectomy
Interventions:   Drug: N1539;   Drug: placebo;   Drug: Morphine
Sponsor:   Alkermes, Inc.
Completed

Wed, 10 Mar 2010 12:00:00 EST

Collection of Blood Samples From Patients With Relapsing MS Who Developed ITP After Receiving Lemtrada

Condition:   Multiple Sclerosis
Intervention:   Other: Blood draw for future biomarker analysis
Sponsor:   Genzyme, a Sanofi Company
Completed

Mon, 24 Dec 2018 12:00:00 EST

TQL-block for Laparoscopic Hemicolectomy

Condition:   Postoperative Pain
Interventions:   Drug: Ropivacaine;   Drug: Acetaminophen;   Device: Patient controlled analgesia;   Drug: Morphine;   Drug: Saline;   Diagnostic Test: Blood samples;   Behavioral: Quality of recovery-15 questionaire;   Diagnostic Test: Orthostatic hypotension
Sponsor:   Zealand University Hospital
Completed

Wed, 27 Jun 2018 12:00:00 EDT

Pharmacokinetics and Pharmacodynamics Study of RPC1063 in RMS

Condition:   Multiple Sclerosis
Intervention:   Drug: RPC1063
Sponsor:   Celgene
Completed

Mon, 13 Jun 2016 12:00:00 EDT

S Ketamine Use in Total Abdominal Hysterectomy

Condition:   Total Abdominal Hysterectomy
Intervention:   Drug: S Ketamine
Sponsor:   KK Women's and Children's Hospital
Withdrawn

Mon, 07 Sep 2015 12:00:00 EDT

Psoas Compartment Block Versus Periarticular Local Anesthetic for Total Hip Arthroplasty

Conditions:   Osteoarthritis;   Arthroplasty
Interventions:   Drug: Ropivacaine with NaCl;   Drug: Epinephrine;   Drug: Morphine;   Drug: Ketorolac Tromethamine;   Drug: Ropivacaine
Sponsor:   William Beaumont Hospitals
Completed

Mon, 18 Jan 2016 12:00:00 EST

PVB vs PECS Block in Breast Surgery

Condition:   Reconstruction Breast Surgery
Interventions:   Procedure: Paravertebral Thoracic block;   Procedure: Pectorals nerve block;   Drug: Levobupivacaine 0.25%;   Drug: Morphine
Sponsor:   Istituti Ospitalieri di Cremona
Completed

Tue, 09 Feb 2016 12:00:00 EST

Analgesic Strategies in Newborns Receiving Prostaglandin Therapy

Condition:   Pain
Interventions:   Drug: acetaminophen and nalbuphine;   Drug: acetaminophen and morphine;   Drug: acetaminophen and reduced dosage of prostaglandin
Sponsor:   Nantes University Hospital
Terminated

Tue, 20 Sep 2005 12:00:00 EDT

Regional vs General Anesthesia in Patients With Hip Fracture Under Treatment With Clopidogrel

Condition:   Hip Fractures
Interventions:   Drug: Fentanyl;   Drug: Propofol;   Drug: Rocuronium;   Drug: Chirochaine;   Drug: Morphine
Sponsor:   Larissa University Hospital
Recruiting

Mon, 23 Jul 2018 12:00:00 EDT

Effects of Visceral Manipulation in Women With Urinary Incontinence

Condition:   Urinary Incontinence
Interventions:   Other: Pelvic Floor muscle training - PFMT;   Other: Visceral Manual Therapy - VMT;   Other: Manual Sham Therapy - MST
Sponsor:   University of the State of Santa Catarina
Completed

Fri, 10 May 2019 12:00:00 EDT

Multimodal Analgesia in Shoulder Arthroplasty

Conditions:   Shoulder Pain;   Opioid Use
Interventions:   Drug: Acetaminophen;   Drug: Celecoxib 200mg;   Drug: Celecoxib 400 mg;   Drug: Ropivacaine;   Drug: Ketorolac;   Drug: Acetaminophen Injectable Product;   Drug: Oxycodone;   Drug: Tramadol;   Drug: Morphine Injectable Solution;   Drug: hydrocodone bitartrate and acetaminophen;   Drug: Morphine;   Drug: Oxycodone Hydrochloride;   Drug: Meloxicam
Sponsor:   Rush University Medical Center
Withdrawn

Mon, 16 Jul 2018 12:00:00 EDT

Colloid Pre-Loading on D-Dimer During Cesarean Section Under Spinal Anesthesia

Condition:   Coagulation Defect; Bleeding
Interventions:   Drug: hydroxyethyl starch (6% 130/0.4);   Drug: Hyperbaric bupivacaine;   Drug: Morphine;   Drug: Isotonic 0.9 sodium chloride (NaCl) solution;   Drug: Ephedrine;   Drug: Atropine
Sponsor:   Assiut University
Completed

Fri, 04 Dec 2015 12:00:00 EST

US-guided SAPB for Rib Fractures in the ED

Conditions:   Rib Fractures;   Rib Fracture Multiple
Interventions:   Drug: Bupivacaine;   Drug: Fentanyl, morphine, hydromorphone, hydrocodone, acetaminophen, ketorolac, gabapentin, ketamine, ibuprofen
Sponsors:   Andrew A Herring;   Oregon Health and Science University;   University of California, Los Angeles
Unknown status

Wed, 08 Aug 2018 12:00:00 EDT

Study of Respiratory Depression When Using a Hydromorphone Pain Protocol

Conditions:   Pain;   Respiratory Depression
Interventions:   Drug: Hydromorphone;   Drug: Usual care group
Sponsor:   Albert Einstein Healthcare Network
Terminated

Wed, 06 Feb 2013 12:00:00 EST

Oxycodone Extended-release in the Treatment of Perioperative Pain in Patients Undergoing Orthopaedic Surgery

Condition:   Surgery
Interventions:   Drug: Extended-release oxycodone;   Drug: Extended- release Oxycodone;   Drug: ketoprofen;   Drug: dipirone;   Drug: dexametasone;   Drug: Morphine IV (rescue)
Sponsor:   Hospital Central Dr. Luis Ortega
Completed

Fri, 12 Sep 2014 12:00:00 EDT

Continuous Infusion for Pain Relief

Conditions:   Regional Anesthesia;   Caeserian Section;   Local Anesthetic
Interventions:   Drug: control group;   Drug: infiltration group
Sponsor:   Tunisian Military Hospital
Unknown status

Thu, 17 Mar 2016 12:00:00 EDT

Effect of Ketorolac on Post Adenotonsillectomy Pain

Condition:   Obstructive Sleep Apnea
Interventions:   Drug: Ketorolac;   Drug: Standard of Care
Sponsor:   Emory University
Recruiting

Fri, 16 Mar 2018 12:00:00 EDT

Observation of Respiration Following Regional Anaesthesia With Intrathecal Opioids for Caesarean Section

Condition:   Respiratory Depression
Intervention:  
Sponsor:   NHS Greater Clyde and Glasgow
Completed

Tue, 16 Oct 2007 12:00:00 EDT

Intrathecal Atropine to Prevent Postoperative Nausea and Vomiting

Condition:   Postoperative Nausea
Interventions:   Drug: Intrathecal atropine;   Drug: dexamethasone
Sponsor:   Assiut University
Completed

Tue, 02 Jan 2018 12:00:00 EST

Pectoralis and Serratus Nerves Block in Thoracic Surgery

Conditions:   Anesthesia;   Surgery;   Block;   Thoracic Injury
Interventions:   Drug: Bupivacaine Hydrochloride;   Device: Ultrasound;   Procedure: Thoracotomy;   Drug: Opioids;   Drug: NSAID
Sponsor:   Soroka University Medical Center
Unknown status

Wed, 18 Jan 2017 12:00:00 EST

Safety, Efficacy and Pharmacokinetic Study of Dexmedetomidine in Pediatrics Ages ≥28 Weeks to ≤44 Weeks Gestational Age

Condition:   Sedation
Interventions:   Drug: Midazolam;   Drug: Fentanyl/Morphine;   Drug: Dexmedetomidine
Sponsor:   Hospira, now a wholly owned subsidiary of Pfizer
Completed

Fri, 09 Jul 2010 12:00:00 EDT

Ibuprofen IV vs Acetaminophen IV for the Treatment of Pain Following Orthopaedic Low Extremity Surgery

Conditions:   Lower Extremity Problem;   Surgery;   Postoperative Pain
Interventions:   Drug: Ibuprofen;   Drug: Acetaminophen
Sponsor:   Indonesia University
Completed

Tue, 11 Dec 2018 12:00:00 EST

Do Corticosteroid Injections During Total Knee Replacement Improve Early Clinical Results?

Conditions:   Osteoarthritis;   Post-traumatic; Arthrosis
Interventions:   Drug: methylprednisolone acetate;   Drug: active comparator
Sponsors:   New Lexington Clinic;   St. Joseph's Health Care London
Completed

Wed, 27 Jun 2007 12:00:00 EDT

Effect of Bilateral Transversus Thoracis Muscle Plane Block in Patients Undergoing Coronary Artery Bypass Graft Surgery.

Conditions:   Coronary Artery Disease;   Pain Syndrome
Intervention:   Procedure: Ultrasound guided Bilateral Transversus Thoracis Muscle Plane block
Sponsor:   University Hospital, Montpellier
Completed

Mon, 19 Apr 2021 12:00:00 EDT

Ultrasound-guided Transmuscular Quadratus Lumborum Block for Elective Caesarean Section.

Condition:   Postoperative Pain
Interventions:   Drug: Ropivacaine;   Drug: Saline;   Drug: Acetaminophen;   Drug: Ibuprofen 400Mg Tablet / Celebra 100 Mg tablet;   Device: ultrasound-guided nerve block;   Drug: Morphine;   Device: Patient-controlled analgesia
Sponsor:   Zealand University Hospital
Completed

Wed, 01 Mar 2017 12:00:00 EST

Behavioral and Neuroimaging Changes After Cognitive Rehab in Traumatic Brain Injuries (TBI) and Mild Cognitive Impairment (MCI)

Conditions:   Mild Cognitive Impairment;   Alzheimer's Disease;   Traumatic Brain Injury
Interventions:   Behavioral: Mnemonic strategy training (MST);   Behavioral: Repeated exposure (XP);   Behavioral: Subtracting Cues training
Sponsors:   VA Office of Research and Development;   Emory University
Completed

Mon, 14 Jul 2008 12:00:00 EDT

Levorphanol as a Second Line Opioid in Cancer Patients

Conditions:   Malignant Neoplasm;   Metastatic Malignant Neoplasm
Interventions:   Drug: Hydrocodone;   Drug: Hydromorphone;   Drug: Hydromorphone Hydrochloride;   Drug: Levorphanol;   Drug: Morphine;   Drug: Morphine Sulfate;   Drug: Oxycodone;   Drug: Oxymorphone;   Drug: Oxymorphone Hydrochloride;   Other: Questionnaire Administration
Sponsors:   M.D. Anderson Cancer Center;   National Cancer Institute (NCI)
Recruiting

Fri, 06 Jul 2018 12:00:00 EDT

Intraoperative Magnesium Sulfate Administration During Orthotopic Liver Transplantation

Condition:   Postoperative Pain
Interventions:   Drug: isotonic saline;   Drug: Magnesium Sulfate
Sponsor:   Fayoum University Hospital
Recruiting

Wed, 24 Oct 2018 12:00:00 EDT

the Effect of the Transversus Abdominis Plane (TAP) Block on the Minimal Laparotomy : a Randomized Controlled Trial

Condition:   Colon Cancer
Intervention:   Procedure: Transversus Abdominis Plane block
Sponsor:   Kaohsiung Medical University Chung-Ho Memorial Hospital
Unknown status

Wed, 17 Aug 2011 12:00:00 EDT

Sublingual Fentanyl and Procedural Burn Pain

Condition:   Burn Pain
Intervention:   Drug: Sublingual Fentanyl Spray
Sponsor:   Loyola University
Terminated

Tue, 16 Sep 2014 12:00:00 EDT

Outcomes Of Perioperative Pregabalin On Total Knee Arthroplasty

Condition:   Pain, Postoperative
Interventions:   Drug: pregabalin;   Drug: Placebo;   Drug: Etoricoxib;   Drug: paracetamol;   Drug: Morphine;   Drug: Ropivacaine
Sponsor:   National University Hospital, Singapore
Completed

Thu, 03 Nov 2016 12:00:00 EDT

A Comparison of Exparel Local Anesthetic in Total Knee Arthroplasty (TKA) Patients

Conditions:   Osteoarthritis, Knee;   Arthroplasty, Replacement, Knee
Interventions:   Drug: Liposomal bupivacaine, 266mg;   Drug: Bupivacaine 0.5 % with Epinephrine;   Drug: Ketorolac 30mg;   Drug: Morphine 10mg;   Drug: Bupivacaine 0.25% with Epinephrine
Sponsor:   Holy Cross Hospital, Florida
Withdrawn

Mon, 09 May 2016 12:00:00 EDT

Impact of Intra- and Postoperative Continuous Infusion of Lidocaine on Analgesia in Vascular Anaesthesia

Conditions:   Abdominal Aorta Aneurysm;   Abdominal Aorta Atheroma;   Surgery;   Pain, Postoperative
Interventions:   Drug: lidocaine 10mg/ml;   Drug: Placebo;   Drug: Metamizole;   Drug: Morphine
Sponsor:   Łukasz Krzych
Suspended

Thu, 31 Dec 2020 12:00:00 EST

Levobupivacaine Prolonged Wound Infusion for Postoperative Pain Relief After Breast Surgery

Conditions:   Acute Pain;   Chronic Pain;   Wound Infusion;   Mastectomy
Interventions:   Drug: Levobupivacaine PCIA (Patient Controlled Intrawound Analgesia);   Drug: saline;   Drug: Levobupivacaine continuous infusion;   Device: intrawound infusion catheter;   Drug: morphine;   Drug: Patrol
Sponsor:   IRCCS Policlinico S. Matteo
Unknown status

Tue, 14 Jan 2014 12:00:00 EST

Non-Inferiority Study to Compare the Effectiveness of the Seldinger Over-the-Wire Technique and the Modified Seldinger Technique

Condition:   Effectiveness and Safety of the Seldinger Wire Technique Using a 145 cm Guidewire With the Modified Seldinger Technique Using a 70 cm Guidewire
Interventions:   Device: Angiodynamic Bioflo Picc IR-KIT (145 cm guidewire) or;   Device: Angiodynamic Bioflo Picc MST-KIT (70 cm guidewire)
Sponsor:   Jena University Hospital
Completed

Tue, 10 Mar 2020 12:00:00 EDT

Additional Effect of Wound Infiltration After Cesarean Section With Optimal Standard Analgesia

Conditions:   Postoperative Pain;   Anesthesia, Local;   Breast Feeding
Intervention:   Device: Continuous wound infiltration
Sponsor:   Poissy-Saint Germain Hospital
Completed

Mon, 17 Dec 2012 12:00:00 EST

Ultrasound-guided Blocks for Ambulatory Knee Arthroscopy

Conditions:   Postoperative Pain;   Postoperative Nausea and Vomiting;   Postoperative Function Level
Interventions:   Procedure: Block of the SN and ONP;   Procedure: Placebo block;   Drug: Paracetamol;   Drug: Morphine;   Drug: Ondansetron;   Drug: Metoclopramide
Sponsor:   Jens Borglum Neimann
Completed

Tue, 23 Apr 2013 12:00:00 EDT

Mu-Opioid Receptor Genetic Polymorphism and Intrathecal Analgesia

Conditions:   Labor Pain;   Post-cesarean Delivery
Intervention:   Procedure: Blood Draw
Sponsor:   Northwestern University
Completed

Thu, 04 Jan 2007 12:00:00 EST

Sublingual Sufentanil Tablet System (SSTS) Versus Intravenous Patient Controlled Analgesia After Back Surgery.

Condition:   Pain, Postoperative
Interventions:   Device: Sublingual sufentanil tablet system;   Drug: Patient-controlled intravenous analgesia
Sponsors:   University Hospital, Antwerp;   Universiteit Antwerpen
Completed

Mon, 30 Jan 2017 12:00:00 EST

Multimodal Drug Infiltration in Total Knee Arthroplasty: Is Posterior Capsular Infiltration Worth the Risk?

Condition:   Osteoarthritis, Knee
Interventions:   Drug: 0.5% bupivacaine 100 mg, morphine sulfate 5 mg, 0.1% epinephrine 0.6 mg, and ketorolac 30 mg mixed NSS up to 100 mL;   Procedure: Drug injection at Anterior soft tissue (25 mL)+Medial gutter area (25 mL)+Lateral gutter area (25 mL)+Posterior capsular infiltration (25 mL);   Procedure: Drug injection at Anterior soft tissue (34 mL)+Medial gutter area (33 mL)+Lateral gutter area (33 mL
Sponsors:   Thammasat University;   Krit Boontanapibul
Completed

Wed, 10 Aug 2016 12:00:00 EDT

Opioid-Free Anesthesia in Cardiac Surgery

Condition:   Anesthesia
Interventions:   Drug: Dexmédétomidine 0.5 g/kg + lidocaine 1.5 mg/kg;   Drug: Remifentanil
Sponsor:   University Hospital, Rouen
Not yet recruiting

Fri, 25 Jun 2021 12:00:00 EDT

Study of Opioid Immunosuppressive Effects

Condition:   Opioid Abuse or Dependence
Intervention:  
Sponsor:   Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Unknown status

Thu, 20 Jun 2013 12:00:00 EDT

The Influence of Peripheral Nerve Blocks in Patients Undergoing Limb Orthopedic Surgery

Conditions:   Pain, Postoperative;   Change; Circulatory;   Surgical Injury
Intervention:   Procedure: 0.25% bupivacaine
Sponsors:   Kaohsiung Medical University Chung-Ho Memorial Hospital;   Kaohsiung Municipal Hsiaokang Hospital
Completed

Fri, 12 Apr 2019 12:00:00 EDT

Incidence of Respiratory Depression in Cesarean Section

Conditions:   Respiratory Depression;   Postoperative Pain
Intervention:  
Sponsors:   Wake Forest University;   Forsyth Medical Center
Terminated

Fri, 13 Aug 2010 12:00:00 EDT

Local Anesthetic Continuous Preperitoneal Infiltration and Wound Hyperalgesia

Condition:   Pain, Postoperative
Interventions:   Drug: continuous ropivacaine preperitoneal infusion;   Drug: intravenous lidocaine infusion;   Drug: parenteral analgesia combining acetaminophen and morphine;   Drug: NaCl
Sponsor:   Assistance Publique - Hôpitaux de Paris
Completed

Mon, 01 Mar 2010 12:00:00 EST

Exploring the Immune Response to SARS-CoV-2 COVID-19 Vaccines in Patients With Relapsing Multiple Sclerosis (RMS) Treated With Ofatumumab

Condition:   Multiple Sclerosis
Intervention:   Drug: Ofatumumab
Sponsor:   Novartis Pharmaceuticals
Recruiting

Mon, 03 May 2021 12:00:00 EDT

Pecto-Intercostal Fascial Block vs. Transversus Thoracic Muscle Plane Block in Cardiac Surgery

Conditions:   Pain, Postoperative;   Coronary Artery Disease
Interventions:   Procedure: Single-injection, ultrasound-guided bilateral PIF block.;   Procedure: Single-injection, ultrasound-guided bilateral TTMP block.
Sponsor:   Ondokuz Mayıs University
Completed

Wed, 10 Mar 2021 12:00:00 EST

A Study of Dose-response Relationship and the Evidence Based Multisensory Stimulation Intervention

Conditions:   Psychotic Disorders;   Anxiety;   Complementary Therapies;   Clinical Trial
Intervention:   Behavioral: multisensory stimulation therapy
Sponsors:   Jianan Psychiatric Center, Ministry of Health and Welfare;   Taiwan Nurses Association;   National Cheng Kung University
Completed

Thu, 19 Aug 2021 12:00:00 EDT

Consumer Understanding and Use of Medication Guides

Condition:   Revised Medication Guide Formats
Intervention:  
Sponsors:   Northwestern University;   Abbott
Completed

Wed, 21 Nov 2012 12:00:00 EST

Individualized Analgesia After Adenotonsillectomy

Condition:   Analgesia
Interventions:   Drug: Individualized opioid analgesia;   Device: conventional opioid analgesia
Sponsor:   Children's Hospital of Fudan University
Completed

Tue, 13 Dec 2016 12:00:00 EST

Dose Escalation of Dexamethasone to Increase Duration of Transversus Abdominal Plane Block Following Cesarean Section

Condition:   Post Surgical Pain
Interventions:   Drug: 2mg Dexamethasone;   Drug: 4mg Dexamethasone;   Drug: Ropivacaine (TAP blocks);   Drug: Morphine;   Drug: Bupivacaine Hydrochloride;   Drug: Normal saline 1ml;   Drug: Normal saline 0.5ml
Sponsor:   University of Alabama at Birmingham
Terminated

Fri, 31 Mar 2017 12:00:00 EDT

Femoral Preincisional Block in Acute Postoperative Pain Management of Surgery Orthopaedic Lower Limb

Condition:   Surgery
Interventions:   Procedure: Femoral block by ultrasound and neurostimulation;   Drug: Intravenous analgesia
Sponsor:   Hospital Central Dr. Luis Ortega
Completed

Fri, 12 Sep 2014 12:00:00 EDT

Shaping Anesthetic Techniques to Reduce Post-operative Delirium

Conditions:   Delirium;   Lumbar Radiculopathy;   Lumbar Osteoarthritis;   Lumbar Spine Disc Degeneration
Interventions:   Procedure: Light sedation with propofol;   Procedure: Induction with propofol;   Procedure: Maintenance anesthetic using a volatile anesthetic;   Procedure: Muscle relaxant during maintenance anesthesia;   Procedure: Pain control with fentanyl;   Procedure: Bispectral Index (BIS) monitoring for depth of anesthesia;   Procedure: Spinal Anesthesia;   Procedure: Midazolam administered during spinal anesthesia;   Procedure: Cerebrospinal fluid collection;   Procedure: Administration of intrathecal morphine
Sponsors:   Johns Hopkins University;   Mercy Medical Center
Completed

Fri, 28 Apr 2017 12:00:00 EDT

Quadratus Lumborum Block : Effect on Acute Pain and Quality of Recovery After Laparoscopic Renal Surgery

Conditions:   Laparoscopic Renal Surgery;   Pain Management;   Nerve Block
Interventions:   Procedure: single-injection QLB(quadratus lumborum block);   Device: Philip CX50 Ultrasound Scanner;   Device: PAJUNK StimuLong;   Drug: single dose ropivacaine;   Drug: Morphine given as IPCA(intravenous patient controlled analgesia)
Sponsor:   Cui Xulei
Completed

Fri, 22 Jul 2016 12:00:00 EDT

Continuous Lornoxicam Infusion for Orthopaedic Surgery

Condition:   Closed Non Comminuted Long Bone Fractures
Interventions:   Drug: Placebo;   Drug: Continuous infusion;   Drug: Scheduled
Sponsor:   Mansoura University
Suspended

Wed, 31 Oct 2012 12:00:00 EDT

PENG Block for Traumatic Hip Fracture in the Emergency Department

Conditions:   Hip Fractures;   Acute Pain;   Emergency Department
Intervention:   Procedure: Ultrasound-guided Pericapsular Nerve Group (PENG) Block
Sponsors:   Dalin Tzu Chi General Hospital;   Far Eastern Memorial Hospital
Enrolling by invitation

Tue, 10 Aug 2021 12:00:00 EDT

Abciximab (ReoPro) as a Therapeutic Intervention for Sickle Cell Vaso-Occlusive Pain Crisis

Conditions:   Sickle Cell Disease;   Hb-SS Disease With Vasoocclusive Pain;   Hemoglobin SS Disease With Vasoocclusive Crisis;   Other Sickle Cell Disease With Vaso-Occlusive Pain;   Hemoglobin SS Disease With Crisis
Interventions:   Drug: Abciximab;   Drug: Placebo;   Other: Intravenous hydration;   Drug: Ibuprofen;   Drug: Parenteral narcotic;   Other: Incentive spirometry;   Other: Supplemental oxygen
Sponsors:   St. Louis University;   Janssen Services, LLC
Withdrawn

Fri, 30 Aug 2013 12:00:00 EDT

50 Hz vs. 25 Hz Magnetic Seizure Therapy for Schizophrenia

Condition:   Schizophrenia
Interventions:   Procedure: 25 Hz magnetic seizure therapy;   Procedure: 50 Hz magnetic seizure therapy
Sponsor:   Shanghai Mental Health Center
Completed

Mon, 26 Dec 2016 12:00:00 EST

Next Generation Personalized Neuroblastoma Therapy

Conditions:   Neuroblastoma;   Cancer
Interventions:   Procedure: Biopsy;   Genetic: Next Generation Sequencing;   Procedure: Tumor Scans;   Procedure: Bone marrow Tests;   Other: Physical Exam;   Other: Eye Exam;   Other: Labs;   Other: Pregnancy Test;   Behavioral: Interviews;   Other: ECG;   Other: Echocardiogram;   Drug: Ribociclib;   Drug: Ceritinib
Sponsors:   Yael P Mosse;   Novartis Pharmaceuticals;   Foundation Medicine
Recruiting

Mon, 23 May 2016 12:00:00 EDT

Optimal Dose of Prophylactic Naloxone in Reducing Opioid-Induced Side Effects in Children/Adolescents

Conditions:   Pain;   Nausea;   Pruritus
Intervention:   Drug: naloxone
Sponsor:   Johns Hopkins University
Completed

Fri, 26 May 2006 12:00:00 EDT

Pharmacologic Impact on Sedation Assessments

Condition:   Pediatric Acute Lung Injury
Intervention:   Other: Pharmacokinetic Sampling and pharmacogenetic analysis
Sponsors:   Children's Hospital of Philadelphia;   National Heart, Lung, and Blood Institute (NHLBI)
Completed

Fri, 16 Apr 2010 12:00:00 EDT

Periarticular Multimodal Drug Injections in Total Knee Arthroplasty

Condition:   Osteoarthritis, Knee
Interventions:   Drug: ropivacaine;   Drug: morphine sulfate;   Drug: ketorolac;   Drug: epinephrine;   Drug: cefuroxime
Sponsor:   Seoul National University Hospital
Completed

Thu, 14 May 2009 12:00:00 EDT

Local Anesthetic Wound Infusion and Functional Recovery After Colon Surgery

Conditions:   Colon Cancer;   Inflammatory Bowel Diseases;   Diverticulitis
Interventions:   Procedure: Epidural analgesia;   Procedure: Wound catheter
Sponsor:   Franco Carli
Terminated

Thu, 04 Feb 2010 12:00:00 EST

Effectiveness of Intraoperative Exparel for Postoperative Pain Control in Total Knee Arthroplasty

Conditions:   Osteoarthritis;   Total Knee Arthroplasty;   Pain Management
Interventions:   Drug: Pain Cocktail with Exparel;   Drug: Pain Cocktail with Ropivacaine
Sponsor:   DeClaire LaMacchia Orthopaedic Institute
Unknown status

Wed, 22 Jun 2016 12:00:00 EDT

A Comparison Study Between Ketamine Versus Tramadol for Pain Management After Major Upper Abdominal Surgery

Condition:   Postoperative Pain
Interventions:   Drug: Tramadol;   Drug: Ketamine
Sponsor:   Attikon Hospital
Completed

Thu, 16 Jul 2015 12:00:00 EDT

Post-Op Pain Control for Prophylactic Intramedullary Nailing.

Conditions:   Bone Metastases;   Lymphoma;   Multiple Myeloma;   Opioid Use;   Pain
Interventions:   Drug: Ketorolac;   Drug: Normal saline;   Drug: Acetaminophen;   Drug: Oxycodone Acetaminophen;   Drug: Morphine;   Drug: Hydrocodone/Acetaminophen;   Drug: Oxycodone
Sponsor:   St. Louis University
Recruiting

Wed, 30 Jan 2019 12:00:00 EST

Impact of Pregabalin in Chronic Users vs. a Perioperative Limited Prescription on Oxycodone Requirement

Conditions:   Postoperative Pain;   Neuropathic Pain
Interventions:   Drug: Pregabalin;   Other: Naive patient
Sponsors:   Christophe Aveline, MD;   Rennes University Hospital
Completed

Mon, 15 Aug 2016 12:00:00 EDT

A Multicentre Study of the Efficacy and Safety of Supplementary Treatment With Cholecalciferol in Patients With Relapsing Multiple Sclerosis Treated With Subcutaneous Interferon Beta-1a 44 µg 3 Times Weekly

Condition:   Multiple Sclerosis
Interventions:   Dietary Supplement: Cholecalciferol (Vitamin D3);   Dietary Supplement: Placebo;   Drug: Rebif
Sponsors:   Merck KGaA, Darmstadt, Germany;   Merck Serono S.A.S, France
Completed

Thu, 09 Sep 2010 12:00:00 EDT

Post Operative Pain Control After Pediatric Hip Surgery

Conditions:   Hip Surgery;   Post Operative Pain Control
Interventions:   Procedure: Lumbar Plexus Catheter;   Procedure: Lumbar Epidural Catheter;   Procedure: Patient Controlled Analgesia;   Drug: Fentanyl;   Drug: Morphine;   Drug: Lorazepam;   Drug: Ondansetron;   Drug: Diphenhydramine;   Drug: Acetaminophen;   Drug: Oxycodone;   Drug: Ropivacaine
Sponsors:   Seattle Children's Hospital;   Seattle Children's Research Institute Center for Clinical and Translational Research
Completed

Mon, 19 Feb 2018 12:00:00 EST

OCT Guided Magmaris RMS in STEMI

Condition:   STEMI
Intervention:   Device: Magmaris resorbable magnesium scaffold
Sponsors:   Universitaire Ziekenhuizen Leuven;   Centre Hospitalier Universitaire Saint Pierre;   Universitair Ziekenhuis Brussel;   CHU de Charleroi;   Jolimont;   Ziekenhuis Oost-Limburg;   University Hospital St Luc, Brussels;   Centre Hospitalier Universitaire Dinant Godinne - UCL Namur;   Le centre hospitalier EpiCURA;   Centre Hospitalier Régional de la Citadelle
Recruiting

Mon, 20 May 2019 12:00:00 EDT

Pharmacokinetics of Sedatives and Analgesics During Extracorporeal Membrane Oxygenation (ECMO) Support

Condition:   Drug Effect
Interventions:   Drug: Dexmedetomidine;   Drug: Fentanyl;   Drug: Midazolam;   Drug: Morphine
Sponsor:   Boston Children's Hospital
Recruiting

Fri, 20 Jul 2018 12:00:00 EDT

Intrathecal Magnesium and Postoperative Analgesia

Condition:   Total Hip Replacement
Intervention:   Drug: intrathecal magnesium sulfate
Sponsor:   University Hospital, Clermont-Ferrand
Completed

Mon, 19 Nov 2007 12:00:00 EST

Evaluation of the Efficacy of Intra-nasal Sufentanil for Analgesia of Vaso-occlusive Crisis in Sickle-cell Adults.

Condition:   Sickle Cell Crisis
Interventions:   Drug: Sufentanil;   Drug: EMONO
Sponsor:   University Hospital, Bordeaux
Not yet recruiting

Tue, 03 Sep 2019 12:00:00 EDT

Multimodal Narcotic Limited Perioperative Pain Control With Colorectal Surgery

Conditions:   Colon Cancer;   Colon Diverticulosis;   Colonic Neoplasms;   Colonic Diverticulitis;   Pain, Postoperative;   Ileus;   Ileus Paralytic;   Ileus; Mechanical;   Constipation Drug Induced;   Constipation;   Rectum Cancer;   Rectum Neoplasm
Interventions:   Drug: Acetaminophen;   Drug: Gabapentin;   Drug: Orphenadrine;   Drug: Lidocaine;   Drug: Marcaine;   Drug: Ketamine;   Drug: Methadone;   Drug: Tramadol;   Drug: Ketorolac;   Drug: Morphine Sulfate;   Drug: Fentanyl;   Drug: Dilaudid;   Drug: Hydrocodone-Acetaminophen Tab 5-325 MG;   Drug: HYDROCODONE/ACETAMINOPHEN 5 Mg-325 Mg ORAL TABLET
Sponsor:   University of Illinois College of Medicine at Peoria
Unknown status

Tue, 08 Nov 2016 12:00:00 EST

Open-Label, Safety, and Efficacy Study of Dexmedetomidine in Preterm Subjects Ages ≥28 Weeks to <36 Weeks Gestational Age

Condition:   Anesthesia
Interventions:   Drug: Dexmedetomidine;   Drug: Midazolam;   Drug: Fentanyl;   Drug: Morphine
Sponsor:   Hospira, now a wholly owned subsidiary of Pfizer
Completed

Thu, 12 Jan 2012 12:00:00 EST

Perioperative Opioid-induced Hyperalgesia and Its Prevention With Ketamine and Methadone

Conditions:   Post Operative Pain;   Hyperalgesia
Interventions:   Drug: ketamine infusion;   Drug: Methadone PCA
Sponsor:   Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Unknown status

Tue, 08 May 2012 12:00:00 EDT

How Does Gabapentin Affects Post-operative Tonsillectomy Pain?

Condition:   Post-operative Pain
Interventions:   Drug: Gabapentin;   Drug: Placebo
Sponsor:   University of British Columbia
Completed

Wed, 27 Feb 2008 12:00:00 EST

Effects of Buprenorphine/Naloxone Dose on Experimental Stress Reactivity and Opioid Abstinence

Conditions:   Heroin Dependence;   Opioid Use Disorder
Interventions:   Drug: Extended release morphine;   Drug: Buprenorphine/Naloxone low dose;   Drug: Buprenorphine/Naloxone moderate dose;   Drug: Buprenorphine/Naloxone high dose;   Drug: Active stressor;   Drug: Placebo stressor
Sponsor:   Wayne State University
Completed

Tue, 10 Jan 2017 12:00:00 EST

Innovative Delivery of Evidence Based Psychotherapy to Women With Military Sexual Trauma

Conditions:   PTSD;   Stress Disorders, Post - Traumatic;   Anxiety Disorders;   Mental Disorders;   Stress Disorders, Traumatic
Intervention:   Behavioral: PE
Sponsors:   Medical University of South Carolina;   Charleston Research Institute
Completed

Wed, 15 Apr 2015 12:00:00 EDT

Study Evaluating Safety and Efficacy of Dexmedetomidine (DEX) in Intubated and Mechanically Ventilated Pediatric Intensive Care Unit (PICU) Subjects

Condition:   Sedation
Interventions:   Drug: Dexmedetomidine;   Drug: Midazolam;   Drug: Fentanyl;   Drug: Morphine
Sponsor:   Hospira, now a wholly owned subsidiary of Pfizer
Completed

Fri, 03 Apr 2009 12:00:00 EDT

An Open Label Extension Study of Ublituximab in Subjects With Relapsing Multiple Sclerosis

Condition:   Relapsing Multiple Sclerosis (RMS)
Intervention:   Biological: Ublituximab
Sponsor:   TG Therapeutics, Inc.
Enrolling by invitation

Fri, 18 Oct 2019 12:00:00 EDT

Efficacy and Safety of IRE for RMs

Condition:   Kidney Cancer
Intervention:   Device: Nano Knife
Sponsor:   Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Unknown status

Mon, 24 Nov 2014 12:00:00 EST

Thoracic Paravertebral Block : Effect on Acute Pain and Chronic Pain of Hepatectomy With Right J-shape Subcostal Incision

Conditions:   Hepatectomy;   Analgesia;   Nerve Block
Interventions:   Procedure: single-injection TPVB + continuous TPVB;   Device: Philip CX50 Ultrasound Scanner;   Device: PAJUNK Contiplex S Catheter;   Drug: single dose ropivacaine;   Drug: continuously infusion of ropivacaine;   Drug: Morphine given as IPCA
Sponsor:   Cui Xulei
Completed

Wed, 29 Jun 2016 12:00:00 EDT

Study of Evobrutinib in Participants With RMS (evolutionRMS 2)

Condition:   Relapsing Multiple Sclerosis
Interventions:   Drug: Evobrutinib;   Drug: Placebo (match to Teriflunomide);   Drug: Teriflunomide;   Drug: Placebo (match to Evobrutinib)
Sponsors:   Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany;   EMD Serono Research & Development Institute, Inc.
Active, not recruiting

Wed, 08 Apr 2020 12:00:00 EDT

Study of Evobrutinib in Participants With RMS (evolutionRMS 1)

Condition:   Relapsing Multiple Sclerosis
Interventions:   Drug: Evobrutinib;   Drug: Placebo (match to Teriflunomide);   Drug: Teriflunomide;   Drug: Placebo (match to Evobrutinib)
Sponsors:   Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany;   EMD Serono Research & Development Institute, Inc.
Active, not recruiting

Wed, 08 Apr 2020 12:00:00 EDT

Dexmedetomidine Supplemented Analgesia in Patients at High-risk of Obstructive Sleep Apnea

Conditions:   Obstructive Sleep Apnea;   Analgesia;   Dexmedetomidine;   High-flow Nasal Cannula;   Sleep Quality
Interventions:   Drug: Dexmedetomidine;   Drug: Placebo
Sponsor:   Peking University First Hospital
Recruiting

Thu, 29 Oct 2020 12:00:00 EDT

Phenylephrine Versus Norepinephrine for Maintenance of Hemodynamic During Cesarean Section Under Spinal Anesthesia

Conditions:   Cesarean Section Complications;   Spinal Anesthesia
Interventions:   Drug: Norepinephrine;   Drug: Phenylephrine
Sponsor:   Centre Hospitalier Régional d'Orléans
Completed

Thu, 21 Feb 2019 12:00:00 EST

Postoperative Pain Management in Patients Undergoing Intramedullary Nail Fixation After Tibia and Femoral Fractures

Conditions:   Femur Fracture;   Tibial Fractures
Intervention:   Other: Use of non-steroid anti-inflammatory drugs (NSAIDS) as an alternative for post-operative pain management after a femur and tibia fracture
Sponsor:   University of Puerto Rico
Not yet recruiting

Thu, 18 Feb 2021 12:00:00 EST