Full text biomedical articles

A review of moxifloxacin for the treatment of drug-susceptible tuberculosis

Anushka Naidoo, Kogieleum Naidoo, Helen McIlleron, Sabiha Essack, Nesri Padayatchi
J Clin Pharmacol. Author manuscript; available in PMC 2018 Nov 1.
Published in final edited form as: J Clin Pharmacol. 2017 Nov; 57(11): 1369–1386. Published online 2017 Jul 24. doi: 10.1002/jcph.968


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Three-photon tissue imaging using moxifloxacin

Seunghun Lee, Jun Ho Lee, Taejun Wang, Won Hyuk Jang, Yeoreum Yoon, Bumju Kim, Yong Woong Jun, Myoung Joon Kim, Ki Hean Kim
Sci Rep. 2018; 8: 9415. Published online 2018 Jun 20. doi: 10.1038/s41598-018-27371-8


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Effect of rifampicin and efavirenz on moxifloxacin concentrations when co-administered in patients with drug-susceptible TB

Anushka Naidoo, Maxwell Chirehwa, Helen McIlleron, Kogieleum Naidoo, Sabiha Essack, Nonhlanhla Yende-Zuma, Eddy Kimba-Phongi, John Adamson, Katya Govender, Nesri Padayatchi, Paolo Denti
J Antimicrob Chemother. 2017 May; 72(5): 1441–1449. Published online 2017 Feb 8. doi: 10.1093/jac/dkx004


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Elevated Plasma Moxifloxacin Concentrations and SLCO1B1 g.−11187G>A Polymorphism in Adults with Pulmonary Tuberculosis

Marc Weiner, Jon Gelfond, Teresa L. Johnson-Pais, Melissa Engle, Charles A. Peloquin, John L. Johnson, Erin E. Sizemore, William R. Mac Kenzie
Antimicrob Agents Chemother. 2018 May; 62(5): e01802-17. Prepublished online 2018 Feb 20. Published online 2018 Apr 26. doi: 10.1128/AAC.01802-17


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Limited Sampling Strategies Using Linear Regression and the Bayesian Approach for Therapeutic Drug Monitoring of Moxifloxacin in Tuberculosis Patients

Simone H. J. van den Elsen, Marieke G. G. Sturkenboom, Onno W. Akkerman, Katerina Manika, Ioannis P. Kioumis, Tjip S. van der Werf, John L. Johnson, Charles Peloquin, Daan J. Touw, Jan-Willem C. Alffenaar
Antimicrob Agents Chemother. 2019 Jul; 63(7): e00384-19. Prepublished online 2019 Apr 22. Published online 2019 Jun 24. doi: 10.1128/AAC.00384-19


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Gender Analysis of Moxifloxacin Clinical Trials

Elisa Chilet-Rosell, Ma Teresa Ruiz-Cantero, Ma Angeles Pardo
J Womens Health (Larchmt) 2014 Jan 1; 23(1): 77–104. doi: 10.1089/jwh.2012.4171


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Two-photon microscopy of Paneth cells in the small intestine of live mice

Won Hyuk Jang, Areum Park, Taejun Wang, Chan Johng Kim, Hoonchul Chang, Bo-Gie Yang, Myoung Joon Kim, Seung-Jae Myung, Sin-Hyeog Im, Myoung Ho Jang, You-Me Kim, Ki Hean Kim
Sci Rep. 2018; 8: 14174. Published online 2018 Sep 21. doi: 10.1038/s41598-018-32640-7


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Activity of Moxifloxacin against Mycobacterium tuberculosis in Acid Phase and Nonreplicative-Persister Phenotype Phase in a Hollow-Fiber Infection Model

Arnold Louie, Brandon Duncanson, Jenny Myrick, Michael Maynard, Jocelyn Nole, David Brown, Stephan Schmidt, Michael Neely, C. A. Scanga, Charles Peloquin, G. L. Drusano
Antimicrob Agents Chemother. 2018 Dec; 62(12): e01470-18. Prepublished online 2018 Sep 24. Published online 2018 Nov 26. doi: 10.1128/AAC.01470-18


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Toxicities of and inflammatory responses to moxifloxacin, cefuroxime, and vancomycin on retinal vascular cells

Hitomi Miyake, Dai Miyazaki, Yumiko Shimizu, Shin-ichi Sasaki, Takashi Baba, Yoshitsugu Inoue, Kazuki Matsuura
Sci Rep. 2019; 9: 9745. Published online 2019 Jul 5. doi: 10.1038/s41598-019-46236-2


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Moxifloxacin modulates inflammation during murine pneumonia

Christoph Beisswenger, Anja Honecker, Andreas Kamyschnikow, Markus Bischoff, Thomas Tschernig, Robert Bals
Respir Res. 2014; 15(1): 82. Published online 2014 Jul 17. doi: 10.1186/1465-9921-15-82


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Moxifloxacin-induced QTc interval prolongations in healthy male Japanese and Caucasian volunteers: a direct comparison in a thorough QT study

Joel Morganroth, Yaning Wang, Michael Thorn, Yuji Kumagai, Stuart Harris, Norman Stockbridge, Robert Kleiman, Rashmi Shah
Br J Clin Pharmacol. 2015 Sep; 80(3): 446–459. Published online 2015 May 22. doi: 10.1111/bcp.12684


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Effects of the Fluoroquinolones Moxifloxacin and Levofloxacin on the QT Subintervals: Sex Differences in Ventricular Repolarization

Jӧrg Täubel, Krishna Prasad, Giuseppe Rosano, Georg Ferber, Helen Wibberley, Samuel Thomas Cole, Leen Van Langenhoven, Sara Fernandes, Dilshat Djumanov, Atsushi Sugiyama
J Clin Pharmacol. 2020 Mar; 60(3): 400–408. Published online 2019 Oct 21. doi: 10.1002/jcph.1534


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Application of Physiologically‐Based and Population Pharmacokinetic Modeling for Dose Finding and Confirmation During the Pediatric Development of Moxifloxacin

Stefan Willmann, Matthias Frei, Gabriele Sutter, Katrin Coboeken, Thomas Wendl, Thomas Eissing, Jörg Lippert, Heino Stass
CPT Pharmacometrics Syst Pharmacol. 2019 Sep; 8(9): 654–663. Published online 2019 Aug 7. doi: 10.1002/psp4.12446


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Moxifloxacin: Clinically compatible contrast agent for multiphoton imaging

Taejun Wang, Won Hyuk Jang, Seunghun Lee, Calvin J. Yoon, Jun Ho Lee, Bumju Kim, Sekyu Hwang, Chun-Pyo Hong, Yeoreum Yoon, Gilgu Lee, Viet-Hoan Le, Seoyeon Bok, G-One Ahn, Jaewook Lee, Yong Song Gho, Euiheon Chung, Sungjee Kim, Myoung Ho Jang, Seung-Jae Myung, Myoung Joon Kim, Peter T. C. So, Ki Hean Kim
Sci Rep. 2016; 6: 27142. Published online 2016 Jun 10. doi: 10.1038/srep27142


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Release of Moxifloxacin from Corneal Collagen Shields

Siwei Zhou, Kristin M. Hunt, Arman S. Grewal, Kimberly M. Brothers, Deepinder K. Dhaliwal, Robert M.Q. Shanks
Eye Contact Lens. Author manuscript; available in PMC 2019 Nov 1.
Published in final edited form as: Eye Contact Lens. 2018 Nov; 44(Suppl 2): S143–S147. doi: 10.1097/ICL.0000000000000421


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Effect of genetic variation in UGT1A and ABCB1 on moxifloxacin pharmacokinetics in South African patients with tuberculosis

Anushka Naidoo, Veron Ramsuran, Maxwell Chirehwa, Paolo Denti, Helen McIlleron, Kogieleum Naidoo, Nonhlanhla Yende-Zuma, Ravesh Singh, Sinaye Ngcapu, Mamoonah Chaudhry, Michael S Pepper, Nesri Padayatchi
Pharmacogenomics. 2018 Jan; 19(1): 17–29. Published online 2017 Dec 6. doi: 10.2217/pgs-2017-0144


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Efficacy and safety of moxifloxacin in community acquired pneumonia: a prospective, multicenter, observational study (CAPRIVI)

Ilija Kuzman, Alexandr Bezlepko, Irena Kondova Topuzovska, László Rókusz, Liudmyla Iudina, Hans-Peter Marschall, Thomas Petri
BMC Pulm Med. 2014; 14: 105. Published online 2014 Jun 30. doi: 10.1186/1471-2466-14-105


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In vivo 3D measurement of moxifloxacin and gatifloxacin distributions in the mouse cornea using multiphoton microscopy

Seunghun Lee, Jun Ho Lee, Jin Hyoung Park, Yeoreum Yoon, Wan Kyun Chung, Hungwon Tchah, Myoung Joon Kim, Ki Hean Kim
Sci Rep. 2016; 6: 25339. Published online 2016 May 3. doi: 10.1038/srep25339


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The Effects of Moxifloxacin on QTc Interval in Healthy Korean Male Subjects

Seol Ju Moon, Jongtae Lee, Hyungmi An, Dong-Seok Yim, Jae-Yong Chung, Kyung-Sang Yu, Joo-Youn Cho, Kyoung Soo Lim
Drugs R D. 2014 Jun; 14(2): 63–71. Published online 2014 Apr 2. doi: 10.1007/s40268-014-0040-1


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Protection of Hamsters from Mortality by Reducing Fecal Moxifloxacin Concentration with DAV131A in a Model of Moxifloxacin-Induced Clostridium difficile Colitis

Charles Burdet, Sakina Sayah-Jeanne, Thu Thuy Nguyen, Christine Miossec, Nathalie Saint-Lu, Mark Pulse, William Weiss, Antoine Andremont, France Mentré, Jean de Gunzburg
Antimicrob Agents Chemother. 2017 Oct; 61(10): e00543-17. Prepublished online 2017 Jul 24. Published online 2017 Sep 22. doi: 10.1128/AAC.00543-17


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