References from scientific journals

Nedocromil sodium for chronic asthma in children.

Sridhar AV, McKean M. Sridhar AV, et al. Cochrane Database Syst Rev. 2006 Jul 19;(3):CD004108. doi: 10.1002/14651858.CD004108.pub2. Cochrane Database Syst Rev. 2006. PMID: 16856028 Review.

The parent's assessment of efficacy was in favour of nedocromil (odds ratio (OR) 0.5 (95% CI 0.3 to 0.8). Nedocromil sodium has a good safety profile. ...Although nedocromil may have advantages over inhaled corticosteroids in terms of side effects, there is a …
The parent's assessment of efficacy was in favour of nedocromil (odds ratio (OR) 0.5 (95% CI 0.3 to 0.8). Nedocromil sodium ha …

Nedocromil sodium for preventing exercise-induced bronchoconstriction.

Spooner CH, Saunders LD, Rowe BH. Spooner CH, et al. Cochrane Database Syst Rev. 2002;(1):CD001183. doi: 10.1002/14651858.CD001183. Cochrane Database Syst Rev. 2002. PMID: 11869595 Review.

OBJECTIVES: Bronchodilator medications have been commonly used to prevent narrowing of airways after exercise, but anti-inflammatory drugs such as nedocromil sodium have also been used. The objective of this review was to assess the effects of a single dose of nedocromi …
OBJECTIVES: Bronchodilator medications have been commonly used to prevent narrowing of airways after exercise, but anti-inflammatory drugs s …

Nedocromil sodium for preventing exercise-induced bronchoconstriction.

Spooner CH, Saunders LD, Rowe BH. Spooner CH, et al. Cochrane Database Syst Rev. 2000;(2):CD001183. doi: 10.1002/14651858.CD001183. Cochrane Database Syst Rev. 2000. PMID: 10796616 Updated. Review.

SELECTION CRITERIA: Randomised trials comparing a single dose of nedocromil sodium with placebo to prevent exercise-induced bronchoconstriction in people over six years of age. ...There were no significant adverse effects reported. REVIEWER'S CONCLUSIONS: Nedocromil …
SELECTION CRITERIA: Randomised trials comparing a single dose of nedocromil sodium with placebo to prevent exercise-induced bronchoco …

Immunopharmacologic profile of nedocromil sodium.

Wasserman SI. Wasserman SI. Allergy Proc. 1995 Mar-Apr;16(2):67-71. doi: 10.2500/108854195778771390. Allergy Proc. 1995. PMID: 7797061 Review.

Nedocromil sodium, a pyranoquinolone, was specifically designed as an agent to suppress allergic inflammation. ...Nedocromil sodium is more potent than cromolyn sodium in preventing mast cell degranulation in selective animal models. ...
Nedocromil sodium, a pyranoquinolone, was specifically designed as an agent to suppress allergic inflammation. ...Nedocromil s …

Nedocromil sodium and airway inflammation in vivo and in vitro.

Devalia JL, Rusznak C, Abdelaziz MM, Davies RJ. Devalia JL, et al. J Allergy Clin Immunol. 1996 Nov;98(5 Pt 2):S51-7; discussion S64-6. J Allergy Clin Immunol. 1996. PMID: 8939177 Review.

We conducted a series of studies investigating the antiinflammatory effects of nedocromil sodium, with particular reference to its effects on human bronchial epithelial cells and eosinophils in vitro and on eosinophils in vivo. ...We also conducted a double-blind placebo-c …
We conducted a series of studies investigating the antiinflammatory effects of nedocromil sodium, with particular reference to its ef …

Clinical pharmacology of nedocromil sodium.

Rocchiccioli KM, Riley PA. Rocchiccioli KM, et al. Drugs. 1989;37 Suppl 1:123-6; discussion 127-36. doi: 10.2165/00003495-198900371-00022. Drugs. 1989. PMID: 2547562 Review.

In attempts to define the clinical pharmacological activity of inhaled nedocromil sodium, various challenge systems, ranging from specific antigen challenge to provocation with chemical irritants such as sulphur dioxide, have been used. ...The increased potency and wider s …
In attempts to define the clinical pharmacological activity of inhaled nedocromil sodium, various challenge systems, ranging from spe …

Nedocromil sodium. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in the treatment of reversible obstructive airways disease.

Gonzalez JP, Brogden RN. Gonzalez JP, et al. Drugs. 1987 Nov;34(5):560-77. doi: 10.2165/00003495-198734050-00004. Drugs. 1987. PMID: 2826101 Review.

Nedocromil sodium is a sodium cromoglycate-like drug which inhibits activation and mediator release from inflammatory cells such as eosinophils, neutrophils, macrophages, monocytes, mast cells and platelets. ...To date no controlled studies have been published comparing …
Nedocromil sodium is a sodium cromoglycate-like drug which inhibits activation and mediator release from inflammatory cells such as e …

Nedocromil sodium: a review of the evidence for a dual mechanism of action.

Corin RE. Corin RE. Clin Exp Allergy. 2000 Apr;30(4):461-8. doi: 10.1046/j.1365-2222.2000.00769.x. Clin Exp Allergy. 2000. PMID: 10718842 Review. No abstract available.


Nedocromil sodium vs. sodium cromoglycate for preventing exercise-induced bronchoconstriction in asthmatics.

Kelly K, Spooner CH, Rowe BH. Kelly K, et al. Cochrane Database Syst Rev. 2000;2000(4):CD002731. doi: 10.1002/14651858.CD002731. Cochrane Database Syst Rev. 2000. PMID: 11034750 Free PMC article. Review.

BACKGROUND: Nedocromil sodium and sodium cromoglycate inhaled shortly before exercise appear to reduce the severity of exercise-induced bronchoconstriction. ...OBJECTIVES: The objective of this review was to compare the effects on post-exercise lung function between prophy …
BACKGROUND: Nedocromil sodium and sodium cromoglycate inhaled shortly before exercise appear to reduce the severity of exercise-induc …

Nedocromil sodium. An updated review of its pharmacological properties and therapeutic efficacy in asthma.

Brogden RN, Sorkin EM. Brogden RN, et al. Drugs. 1993 May;45(5):693-715. doi: 10.2165/00003495-199345050-00007. Drugs. 1993. PMID: 7686465 Review.

Nedocromil sodium has also been shown to improve symptoms when added to existing treatment with methylxanthines and corticosteroids. Some studies show nedocromil sodium to be successful replacement therapy for methylxanthines, in addition to enabling a modest reduct …
Nedocromil sodium has also been shown to improve symptoms when added to existing treatment with methylxanthines and corticosteroids. …