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Paclitaxel - National Cancer Institute

Paclitaxel is approved to be used alone or with other drugs to treat: AIDS-related Kaposi sarcoma. It is used as second-line therapy. Breast cancer ...
www.cancer.gov/about-cancer/treatment/drugs/paclitaxel

Paclitaxel - PubMed

Paclitaxel is the first microtubule-stabilizing agent identified and considered to be the most significant advance in chemotherapy of the past two ...
pubmed.ncbi.nlm.nih.gov/31029218/

Paclitaxel with polyoxyethylated castor oil Injection ...

Paclitaxel (with polyoxyethylated castor oil) injection comes as a liquid to be injected over 3 or 24 hours intravenously by a doctor or nurse in a ...
medlineplus.gov/druginfo/meds/a607070.html

Paclitaxel C47H51NO14 - PubChem

Paclitaxel is a tetracyclic diterpenoid isolated originally from the bark of the Pacific yew tree, Taxus brevifolia. It is a mitotic inhibitor used in ...
pubchem.ncbi.nlm.nih.gov/compound/paclitaxel

Taxol paclitaxel mechanisms of action

Paclitaxel, an antitumor drug that is demonstrating encouraging activity in human malignancies, is likely to play a major role in cancer chemotherapy ...
pubmed.ncbi.nlm.nih.gov/7865431/

A Review of Paclitaxel and Novel Formulations Including ...

Paclitaxel is a commonly used chemotherapeutic agent with a broad spectrum of activity against cancers in humans. In 1992, paclitaxel was approved by ...
pubmed.ncbi.nlm.nih.gov/26179168/

Success Story Taxol - National Cancer Institute

A computer-generated model of a Taxol molecule. Courtesy of NCI. 1991. Taxol (NSC 125973) Paclitaxel, the most well-known natural-source cancer drug ...
dtp.cancer.gov/timeline/flash/success_stories/S2_taxol.htm

Peripheral Neuropathy Induced by Paclitaxel Recent ...

Paclitaxel is an antineoplastic agent derived from the bark of the western yew, Taxus brevifolia, with a broad spectrum of activity. Because paclitaxe ...
www.ncbi.nlm.nih.gov/pmc/articles/PMC2430667/

PDF Paclitaxel Protein-Bound Nab-paclitaxel ABRAXANE

paclitaxel, which can be given every 3 weeks (or weekly). This may be less convenient for some patients due to weekly treatments and no break between ...
www.pbm.va.gov/PBM/clinicalguidance/drugmonographs/Paclitaxel_Protein-Bound_Drug_Monograph.pdf

How Taxolpaclitaxel kills cancer cells

Paclitaxel treatment reduces the tension on kinetochores that maintain bipolar attachment (Waters et al., 1998), and is a useful tool both for ...
www.ncbi.nlm.nih.gov/pmc/articles/PMC4161504/

Carboplatin and Paclitaxel for Advanced Endometrial Cancer ...

Purpose: Limitations of the paclitaxel-doxorubicin-cisplatin (TAP) regimen in the treatment of endometrial cancer include tolerability and cumbersome ...
pubmed.ncbi.nlm.nih.gov/33078978/

PDF Taxol paclitaxel injection label

Paclitaxel is a white to off-white crystalline powder with the empirical formula . C. 47 H 51 NO 14 and a molecular weight of 853.9. It is highly ...
www.accessdata.fda.gov/drugsatfda_docs/label/2011/020262s049lbl.pdf

Paclitaxel-d5 C47H51NO14 - PubChem

Paclitaxel is an antineoplastic agent which acts by inhibitor of cellular mitosis and which currently plays a central role in the therapy of ovarian ...
pubchem.ncbi.nlm.nih.gov/compound/Paclitaxel-d5

Taxol C47H51NO14 - PubChem

Paclitaxel is an antineoplastic agent which acts by inhibitor of cellular mitosis and which currently plays a central role in the therapy of ovarian ...
pubchem.ncbi.nlm.nih.gov/compound/taxol

Using Genetic Profile to Determine the Treatment for ...

Cohort B: Participants who have certain gene changes will receive paclitaxel, bevacizumab, and dostarlimab. Cohort C: If the participant and the study ...
www.clinicaltrials.gov/ct2/show/NCT05065021

Paclitaxel in Breast Cancer - PubMed

Paclitaxel has emerged as an important agent in the treatment of breast cancer. The efficacy and tolerability of this agent, as well as its lack of ...
pubmed.ncbi.nlm.nih.gov/10388129/

Cyclin dEpendent Kinase in tRiple nEGatIVe brEast canceR ...

CAREGIVER is a prospective, randomized, multicenter, open, five-arm study with unequal allocation ratios of 1:1:2:1:2 (palbociclib : paclitaxel ...
clinicaltrials.gov/ct2/show/NCT05067530

Albumin-bound paclitaxel a next-generation taxane

Taxanes are standard treatment for metastatic breast cancer; however, the solvents used as vehicles in these formulations cause severe toxicities. The ...
pubmed.ncbi.nlm.nih.gov/16722814/

DailyMed - PACLITAXEL injection solution

Paclitaxel Injection, USP is a clear colorless to slightly yellow viscous solution. It is supplied as a nonaqueous solution intended for dilution with ...
dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=40c0abf0-06ad-8658-a784-6554a540a768

DOCX Possible Side Effects of Carboplatin and Paclitaxel

Possible Side Effects of Carboplatin and Paclitaxel (Table Version Date: April 28, 2021) COMMON, SOME MAY BE SERIOUS: In 100 people receiving ...
ctep.cancer.gov/protocolDevelopment/sideeffects/regimes/SideEffects-Carboplatin-Paclitaxel.docx