Relationship between telomeres, aging and cancer.


All cells have a scheduled life, with which they are synthesized, multiply and, ultimately, are exposed to apoptosis (cell death), when they no longer work .

It often helps think about cell replication as an outdated photocopier machine: the more cell is copied, the more blurry and displaced images.Over time, the genetic material of the cell ( DNA ) begins to collapse, and the cell itself becomes a pale copy of the original. When this happens, the programmed death cell allows the new cell to take and save the system systems.

The number of times when the cell can divide, limited by a phenomenon known as the limit of the hay.This describes the action by which the separation process (known as mitosis) gradually harms genetic material, in particular, part of the DNA called telomere.

The Hayflick limit determines that the average cell will be divided from 50 to 70 times before apoptosis.

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Understanding the Telomeres )

chromosomes -Similar structure structure, located inside the cell encoder. The chromosome is made of protein and a DNA molecule.

At each end of the chromosome there is a telomere that people are often compared to the plastic tips at the ends of the lace. Telomeres are important because they prevent the chromosomes collapsed from sticking together or They twist into the ring.

Each time the cell is divided, double pressed from DNA actions to copy genetic information. When this happens, DNA coding is duplicated, but not a telemer.When the copy is completed, and the mitosis begins, the place where the cell increases through parts, is on the teleaux.

As such, with each generation of cells, the telomerer becomes shorter and shorter, until it can no longer maintain the integrity of the chromosome. It was then then apoptosis arises.

Teleamers’ relationships to aging and cancer

Scientists can use the telomere length to determine the age of the cell and the greatest replication remains.As a cell division slows down, it is subjected to a progressive deterioration, known as a sedencing , which we generally call as aging .Cell aging explains why our bodies and tissues begin to change when we grow up. At the end, all our ‘deadly’ and .

Everything, that is, but one. Cancer cancer is a type of cell that can really be considered ‘immortal’. Unlike normal cells, cancer cells are not subjected to programmed cell death, but they can continueless multiplying endlessly .

This, in itself, violates the balance of cellular communication in the body. If a cell type is allowed for the replication of an indispensable, it can displace all others and undermine the key biological functions .This is what happens with cancer and why these ‘immortal’ cells can cause disease and death.

It is believed that cancer occurs because the genetic mutation can cause the production of an enzyme known as a telomerase that avoids the shortening of telomeres.

Although each cell in the body has genetic coding for the production of telomerase, only certain cells need it.The sperm cells, for example, you must deactivate the shortening of the telomere to make more than 50 copies of yourself; Otherwise, pregnancy can never happen.

If genetic setback is inadvertently spinning the production of telomerase, it can cause abnormal cells to multiply and form tumors.It is believed that, as the hope of life of life continues to grow, the possibilities that this is done not only more, but eventually become inevitable.

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