Clinical Trials

A Study to Evaluate the Efficacy and Safety of BRL 49653C in Non-insulin Dependent Diabetes

Condition:   Diabetes Mellitus Non Insulin Dependent Oral Agent Therapy
Interventions:   Drug: BRL 49653C;   Drug: Placebo
Sponsor:   National Taiwan University Hospital
Completed

Mon, 15 Oct 2012 12:00:00 EDT

Vein-Coronary Atherosclerosis And Rosiglitazone After Bypass Surgery: The VICTORY Trial

Conditions:   Diabetes;   Coronary Artery Bypass Grafting
Intervention:   Drug: Rosiglitazone or placebo
Sponsors:   Laval University;   GlaxoSmithKline
Completed

Thu, 15 Sep 2005 12:00:00 EDT

Rosiglitazone Adjunctive Therapy for Severe Malaria in Children

Condition:   Malaria
Interventions:   Drug: Rosiglitazone;   Drug: Placebo
Sponsors:   Centro de Investigacao em Saude de Manhica;   University Health Network, Toronto;   Barcelona Institute for Global Health
Active, not recruiting

Tue, 01 Mar 2016 12:00:00 EST

A Trial of Rosiglitazone for Ulcerative Colitis

Conditions:   Ulcerative Colitis;   Inflammatory Bowel Disease
Interventions:   Drug: Rosiglitazone;   Drug: Placebo
Sponsors:   James Lewis;   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK);   GlaxoSmithKline
Completed

Fri, 18 Jul 2003 12:00:00 EDT

Identification of Null Allelic Variant of CYP2C8 In A Korean Population

Condition:   Healthy
Interventions:   Drug: Rosiglitazone;   Genetic: CYP2C8 genotype
Sponsor:   Inje University
Completed

Fri, 07 Jun 2013 12:00:00 EDT

Insulin Resistance and Intramyocellular Lipid Content in Glucose Intolerant Subjects Receiving Rosiglitazone

Condition:   Insulin Sensitivity
Interventions:   Drug: Rosiglitazone;   Drug: Placebo
Sponsors:   University of Texas Southwestern Medical Center;   GlaxoSmithKline
Completed

Wed, 03 Sep 2008 12:00:00 EDT

Rosiglitazone (Avandia) vs. Placebo for Androgen Dependent Prostate Cancer

Conditions:   Adenocarcinoma of the Prostate;   Prostate Cancer
Interventions:   Drug: Rosiglitazone;   Other: Placebo
Sponsors:   Massachusetts General Hospital;   Dana-Farber Cancer Institute
Completed

Fri, 16 Sep 2005 12:00:00 EDT

Rosiglitazone Effects on Cognition for Adults in Later Life

Condition:   Mild Cognitive Impairment
Intervention:   Drug: Rosiglitazone
Sponsors:   University of Washington;   National Institute on Aging (NIA);   GlaxoSmithKline
Unknown status

Thu, 20 Oct 2005 12:00:00 EDT

Infergen, Ribavirin & Avandia in Previous Relapsers or Nonresponders to Pegylated Interferon and Ribavirin

Condition:   Hepatitis C
Intervention:   Drug: rosiglitazone
Sponsors:   Brooke Army Medical Center;   InterMune
Completed

Wed, 21 Sep 2005 12:00:00 EDT

Effects of Rosiglitazone and Metformin on Metabolism in Type 2 Diabetes

Conditions:   Insulin Sensitivity;   Type 2 Diabetes
Interventions:   Drug: Rosiglitazone;   Drug: Metformin;   Drug: Placebo
Sponsors:   Turku University Hospital;   SmithKline Beecham
Completed

Tue, 18 Aug 2015 12:00:00 EDT

Drug-Drug Interaction Study Between Quinine Sulfate and Rosiglitazone

Condition:   Healthy
Interventions:   Drug: Rosiglitazone 4 mg Tablets;   Drug: Quinine Sulfate 324 mg Capsules
Sponsors:   Mutual Pharmaceutical Company, Inc.;   Cetero Research, San Antonio
Completed

Wed, 05 Nov 2008 12:00:00 EST

11ß-HSD1 and Metabolic Syndrome

Conditions:   Metabolic Syndrome;   Impaired Glucose Tolerance
Intervention:   Drug: rosiglitazone
Sponsor:   Charite University, Berlin, Germany
Completed

Thu, 31 Aug 2006 12:00:00 EDT

Effect of Rosiglitazone on the Vascular Biology of Human Fat Tissue

Conditions:   Metabolic Syndrome;   Insulin Resistance
Interventions:   Drug: Rosiglitazone;   Drug: Placebo
Sponsors:   University of Massachusetts, Worcester;   GlaxoSmithKline
Completed

Fri, 25 Jun 2010 12:00:00 EDT

Rosiglitazone Effect on Mitochondria and Lipoatrophy

Condition:   HIV Infections
Interventions:   Drug: Rosiglitazone;   Drug: Placebo
Sponsors:   National Institute of Allergy and Infectious Diseases (NIAID);   GlaxoSmithKline
Completed

Wed, 23 Aug 2006 12:00:00 EDT

Effect of Rosiglitazone Versus Placebo on Cardiovascular Performance and Myocardial Triglyceride

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: rosiglitazone;   Drug: placebo
Sponsors:   University of Texas Southwestern Medical Center;   GlaxoSmithKline;   Biosite
Completed

Mon, 22 Jan 2007 12:00:00 EST

Rosiglitazone Maleate in Treating Patients With Oral Leukoplakia

Condition:   Oral Leukoplakia
Interventions:   Drug: rosiglitazone maleate;   Other: laboratory biomarker analysis
Sponsor:   National Cancer Institute (NCI)
Completed

Tue, 29 Aug 2006 12:00:00 EDT

A Drug-Drug Interaction Study of the Effects of XL184 (Cabozantinib) on Rosiglitazone in Subjects With Solid Tumors

Conditions:   Papillary Thyroid Cancer;   Follicular Thyroid Cancer;   Huerthle Cell Thyroid Cancer;   Renal Cell Carcinoma
Interventions:   Drug: rosiglitazone;   Drug: XL184
Sponsor:   Exelixis
Completed

Fri, 09 Apr 2010 12:00:00 EDT

Insulin Resistance in Patients With Mood Disorder

Conditions:   Depression;   Bipolar Disorder;   Insulin Resistance
Intervention:   Drug: rosiglitazone
Sponsor:   Stanford University
Completed

Thu, 20 Oct 2005 12:00:00 EDT

Evaluating the Effects of Electroacupuncture and Rosiglitazone Combined Therapy

Condition:   Type 2 Diabetes Mellitus With Features of Insulin Resistance
Interventions:   Other: EA + Rosiglitazone;   Drug: TZD
Sponsor:   China Medical University Hospital
Completed

Fri, 13 Apr 2012 12:00:00 EDT

Rosiglitazone And Fenofibrate Additive Effects on Lipids (RAFAEL)

Conditions:   Hypertriglyceridemia in Type 4 Hyperlipidemia;   Non Diabetic Subjects With Normoglycemia
Interventions:   Drug: Rosiglitazone;   Drug: Placebo (Rosiglitazone);   Drug: Placebo (Fenofibrate);   Drug: Fenofibrate
Sponsors:   Ahmad Slim;   GlaxoSmithKline
Terminated

Fri, 09 Jan 2009 12:00:00 EST

Effects of Rosiglitazone and Alpha-lipoic Acid on the Patients With Pathologically Proved NASH

Condition:   NASH (Non-alcoholic Steato-hepatitis)
Interventions:   Drug: Rosiglitazone;   Drug: alpha-lipoic acid;   Drug: Rosiglitazone/alpha-lipoic acid
Sponsors:   Seoul St. Mary's Hospital;   GlaxoSmithKline
Terminated

Mon, 01 Aug 2011 12:00:00 EDT

Effects of ROSIglitazone on Inflammatory Markers and Adipokines in Diabetic Patients Using an Angiotensin Receptor Blocker (TELmisartan) - The ROSITEL Study

Condition:   Type 2 Diabetes Mellitus
Interventions:   Drug: rosiglitazone;   Drug: metformin or sulfonylurea
Sponsors:   Dr. Milan Gupta;   GlaxoSmithKline
Completed

Thu, 14 Jun 2007 12:00:00 EDT

Effects of Rosiglitazone on the Metabolic Phenotype of Impaired Glucose Tolerance in Youth

Conditions:   Obesity;   Impaired Glucose Tolerance;   Type 2 Diabetes Mellitus
Interventions:   Drug: Rosiglitazone;   Drug: Placebo
Sponsor:   Yale University
Completed

Tue, 19 Dec 2006 12:00:00 EST

The Effect of Glitazone Treatment on Bone Marrow and Bone Marrow Cells

Conditions:   Change in Bone Mineral Density;   Change in Bone Marrow Fat Content
Interventions:   Drug: Rosiglitazone;   Drug: Placebo pill
Sponsor:   University of Aarhus
Completed

Thu, 07 Feb 2008 12:00:00 EST

Preferred Treatment of Type 1.5 Diabetes

Condition:   Type 2 Diabetes Mellitus
Interventions:   Drug: rosiglitazone;   Drug: glyburide
Sponsors:   University of Washington;   Seattle Institute for Biomedical and Clinical Research;   GlaxoSmithKline
Completed

Mon, 19 Sep 2005 12:00:00 EDT

Gene Regulation by Thiazolidinediones

Condition:   Inflammatory Bowel Disease
Intervention:   Drug: Rosiglitazone
Sponsors:   James Lewis;   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Completed

Wed, 05 Dec 2007 12:00:00 EST

Malignancy Meta Analysis for BRL49653

Condition:   Diabetes Mellitus, Type 2
Intervention:   Drug: allocation of treatment with metformin or rosiglitazone
Sponsor:   GlaxoSmithKline
Completed

Mon, 06 Sep 2010 12:00:00 EDT

Avandia™ + Amaryl™ or Avandamet™ Compared With Metformin (AVALANCHE™ Study)

Condition:   Type 2 Diabetes Mellitus
Interventions:   Drug: Avandamet;   Drug: Avandia and Amaryl;   Drug: Metformin
Sponsors:   Canadian Heart Research Centre;   GlaxoSmithKline
Completed

Fri, 19 Aug 2005 12:00:00 EDT

A Pilot Study of Rosiglitazone in the Treatment of GH Secreting Pituitary Adenomas

Condition:   Pituitary Tumor
Intervention:   Drug: Rosiglitazone
Sponsor:   Zhaoyun Zhang
Unknown status

Fri, 13 Oct 2017 12:00:00 EDT

An Evaluation of Exenatide and Rosiglitazone in Subjects With Type 2 Diabetes Mellitus

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: exenatide;   Drug: rosiglitazone
Sponsors:   AstraZeneca;   Eli Lilly and Company
Completed

Fri, 26 Aug 2005 12:00:00 EDT

The Use of Rosiglitazone to Treat Asthma

Condition:   Asthma
Intervention:   Drug: rosiglitazone
Sponsor:   Creighton University
Completed

Wed, 13 Feb 2008 12:00:00 EST

EMPOWIR:Enhance the Metabolic Profile of Women With Insulin Resistance

Conditions:   Hyperinsulinemia;   Insulin Resistance;   Obesity
Intervention:   Drug: metformin and rosiglitazone
Sponsors:   New York Medical College;   Albert Einstein College of Medicine;   University of Tennessee
Completed

Mon, 18 Feb 2008 12:00:00 EST

Rosiglitazone in Treating Patients With Liposarcoma

Condition:   Sarcoma
Intervention:   Drug: rosiglitazone maleate
Sponsors:   Dana-Farber Cancer Institute;   National Cancer Institute (NCI)
Completed

Fri, 09 May 2003 12:00:00 EDT

Mild Alzheimer''s Disease to Assess the of Extended Release Formulation of Rosiglitazone (RSG XR)

Condition:   Alzheimer's Disease
Intervention:   Drug: Rosiglitazone (Extended Release)
Sponsor:   GlaxoSmithKline
Completed

Mon, 02 Jun 2008 12:00:00 EDT

Open-Label Extension Assessing Long-Term Safety Of Rosiglitazone In Subjects With Mild To Moderate Alzheimer's Disease

Condition:   Alzheimer's Disease
Intervention:   Drug: rosiglitazone
Sponsor:   GlaxoSmithKline
Completed

Wed, 27 Sep 2006 12:00:00 EDT

Rosiglitazone for Clozapine Induced Glucose Metabolism Impairment

Condition:   Schizophrenia
Interventions:   Drug: rosiglitazone;   Drug: placebo
Sponsors:   Massachusetts General Hospital;   National Alliance for Research on Schizophrenia and Depression;   Stanley Medical Research Institute
Completed

Thu, 15 Jun 2006 12:00:00 EDT

Comparing Tricor, Avandia, or Weight Loss to Lower Cardiovascular Risk Factors in People With High Triglycerides.

Conditions:   Insulin Resistance;   Hypertriglyceridemia
Interventions:   Drug: Rosiglitazone;   Drug: Fenofibrate;   Behavioral: Weight Loss
Sponsors:   Stanford University;   Abbott
Completed

Fri, 16 Sep 2005 12:00:00 EDT

The Effect of Rosiglitazone on Ischemia-reperfusion-injury Using Annexin A5 Scintigraphy.

Conditions:   Ischemia-Reperfusion Injury;   The Metabolic Syndrome
Intervention:   Drug: rosiglitazone
Sponsors:   Radboud University;   GlaxoSmithKline
Completed

Wed, 29 Nov 2006 12:00:00 EST

Effect of Metformin and Rosiglitazone Over no Diabetic With Metabolic Syndrome Patients.

Condition:   Insulin Resistance
Interventions:   Drug: Metformin group;   Drug: Rosiglitazone group;   Drug: Placebo oral tablet
Sponsors:   J JESUS VENEGAS, MD;   Instituto Mexicano del Seguro Social;   National Council of Science and Technology, Mexico
Completed

Fri, 01 Nov 2019 12:00:00 EDT

The Effect Of AVANDIA On The Late Asthmatic Response

Condition:   Asthma
Interventions:   Drug: Rosiglitazone;   Drug: Placebo
Sponsor:   GlaxoSmithKline
Completed

Thu, 27 Apr 2006 12:00:00 EDT

A Study Of Rosiglitazone Plus Insulin To Treat Type 2 Diabetes Mellitus Patients

Conditions:   Type 2 Diabetes Mellitus;   Diabetes Mellitus, Type 2
Intervention:   Drug: Rosiglitazone 4 mg
Sponsor:   GlaxoSmithKline
Completed

Fri, 07 Jul 2006 12:00:00 EDT

Comparison of the Efficacy and Tolerability of the Addition of AVANDIA to Submaximal Doses of Metformin

Condition:   Diabetes Mellitus, Type 2
Intervention:   Drug: Rosiglitazone
Sponsor:   GlaxoSmithKline
Completed

Fri, 13 Jul 2007 12:00:00 EDT

Study to Determine the Utility of Novel Technologies and Biomarkers to Measure Human Response to Rosiglitazone Maleate

Condition:   Diabetes Mellitus, Type 2
Intervention:   Drug: rosiglitazone maleate
Sponsor:   GlaxoSmithKline
Completed

Wed, 31 Oct 2007 12:00:00 EDT

Physical Exercise Versus Rosiglitazone in CAD and Prediabetes

Condition:   Impaired Glucose Tolerance
Interventions:   Drug: rosiglitazone;   Behavioral: physical exercise;   Other: control
Sponsor:   University of Leipzig
Completed

Mon, 12 May 2008 12:00:00 EDT

AVANDIA With Glyburide In African American And Hispanic Patients With Type 2 Diabetes Not Controlled by Glyburide Alone

Condition:   Diabetes Mellitus, Type 2
Intervention:   Drug: Rosiglitazone
Sponsor:   GlaxoSmithKline
Completed

Tue, 06 Jun 2006 12:00:00 EDT

Open-Label Extension Study Of Rosiglitazone XR As Adjunctive Therapy In Subjects With Mild-to-Moderate Alzheimers

Condition:   Alzheimer's Disease
Intervention:   Drug: Rosiglitazone XR
Sponsor:   GlaxoSmithKline
Terminated

Fri, 22 Jun 2007 12:00:00 EDT

Prescription Patterns, Resource Utilization & Costs - Add-on Therapy With Anti Dipeptidyl Peptidase-IVs vs Rosiglitazone

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Rosiglitazone + Metformin;   Drug: Sitagliptin + Metformin
Sponsor:   GlaxoSmithKline
Completed

Mon, 11 Apr 2011 12:00:00 EDT

A Study for Pre-diabetic Patients With Cholesterol Lowering Drugs

Condition:   Pre-diabetes
Interventions:   Drug: Rosiglitazone;   Drug: Placebo Rosiglitazone;   Drug: Simvastatin
Sponsors:   University of Chicago;   GlaxoSmithKline
Completed

Wed, 28 Jan 2009 12:00:00 EST

Rosiglitazone in Treating Patients With Newly Diagnosed ACTH-Secreting Pituitary Tumor (Cushing Disease)

Condition:   Cushing's Disease
Intervention:   Drug: rosiglitazone maleate
Sponsors:   Jonsson Comprehensive Cancer Center;   National Institutes of Health (NIH)
Terminated

Mon, 11 Feb 2008 12:00:00 EST

Rosiglitazone And Plaque Study for Type 2 Diabetes Mellitus

Condition:   Non-insulin-dependent Diabetes Mellitus
Intervention:   Drug: rosiglitazone
Sponsor:   GlaxoSmithKline
Completed

Tue, 04 Oct 2005 12:00:00 EDT

Brain Imaging Study Of Rosiglitazone Efficacy And Safety In Alzheimer's Disease

Condition:   Alzheimer's Disease
Interventions:   Drug: Rosiglitazone;   Other: Placebo
Sponsor:   GlaxoSmithKline
Completed

Wed, 14 Dec 2005 12:00:00 EST

Rosiglitazone (Extended Release Tablets) As Monotherapy In Subjects With Mild To Moderate Alzheimer's Disease

Condition:   Alzheimer's Disease
Intervention:   Drug: Rosiglitazone
Sponsor:   GlaxoSmithKline
Completed

Mon, 29 Jan 2007 12:00:00 EST

Study Of Rosiglitazone XR In Subjects With Mild-to-Moderate Alzheimers

Condition:   Alzheimer's Disease
Intervention:   Drug: Rosiglitazone XR
Sponsor:   GlaxoSmithKline
Terminated

Mon, 29 Oct 2007 12:00:00 EDT

Influence of Glitazones on the Vasodilatory Effect of High-density Lipoprotein (HDL) Lipoproteins

Condition:   Type 2 Diabetes
Interventions:   Drug: pioglitazone;   Drug: rosiglitazone
Sponsor:   Centre Hospitalier Universitaire Dijon
Completed

Thu, 06 Aug 2009 12:00:00 EDT

A Study Of BRL49653C For The Treatment Of Type 2 Diabetes

Condition:   Diabetes Mellitus, Type 2
Intervention:   Drug: rosiglitazone
Sponsor:   GlaxoSmithKline
Completed

Mon, 03 Sep 2007 12:00:00 EDT

The Impact of Rosiglitazone on Regression of Atherosclerosis

Condition:   Diabetes Mellitus, Atherosclerosis
Intervention:   Drug: Rosiglitazone
Sponsors:   National Taiwan University Hospital;   National Science Council, Taiwan
Suspended

Wed, 14 Sep 2005 12:00:00 EDT

Role of Rosiglitazone on Pre-Diabetes Mellitus and Coronary Artery Disease

Conditions:   Prediabetes;   Coronary Artery Disease;   Insulin Resistance;   Glucose Intolerance
Interventions:   Drug: placebo tablet;   Drug: rosiglitazone (4 mg)/day
Sponsor:   National Cheng-Kung University Hospital
Completed

Tue, 10 Apr 2012 12:00:00 EDT

Rosiglitazone in Treating Patients With Pituitary Tumors

Condition:   Brain and Central Nervous System Tumors
Intervention:   Drug: rosiglitazone maleate
Sponsors:   Jonsson Comprehensive Cancer Center;   National Institutes of Health (NIH)
Terminated

Fri, 15 Feb 2008 12:00:00 EST

An Efficacy and Safety Study of Fixed-dose Rosiglitazone/Glimepiride to Treat Chinese Type 2 Diabetes Patients

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: rosiglitazone/glimepiride fix dose combination;   Drug: glimepiride
Sponsor:   GlaxoSmithKline
Terminated

Mon, 17 Oct 2011 12:00:00 EDT

Rosiglitazone (Avandia®) Treatment in HIV: Its Effect on Blood Vessels

Conditions:   Atherosclerosis;   HIV Infections
Interventions:   Drug: Rosiglitazone maleate;   Drug: Placebo
Sponsor:   University of British Columbia
Completed

Fri, 02 Sep 2005 12:00:00 EDT

Rosiglitazone on Microalbuminuria in Type 2 Diabetics

Condition:   Diabetes Mellitus, Type 2
Intervention:   Drug: Rosiglitazone
Sponsor:   GlaxoSmithKline
Completed

Fri, 13 Jul 2007 12:00:00 EDT

Combination Drug Study of Bexarotene and Rosiglitazone to Treat CTCL

Conditions:   Cutaneous T-cell Lymphoma;   Mycosis Fungoides;   Sezary Syndrome
Intervention:   Drug: Rosiglitazone and Bexarotene
Sponsor:   Vanderbilt University
Completed

Thu, 15 Sep 2005 12:00:00 EDT

Effects of Colesevelam HCl, Rosiglitazone, Sitagliptin on Control of Blood Glucose and Lipids in Type 2 Diabetes Patients Whose Blood Glucose Isn't Completely Controlled With Metformin

Conditions:   Type 2 Diabetes;   Hyperlipidemia
Interventions:   Drug: Colesevelam HCl;   Drug: rosiglitazone maleate;   Drug: sitagliptin phosphate
Sponsor:   Daiichi Sankyo, Inc.
Completed

Fri, 08 Jun 2007 12:00:00 EDT

Study to Compare Pioglitazone and Rosiglitazone in Subjects With Type 2 Diabetes Mellitus and Dyslipidemia

Condition:   Diabetes Mellitus
Interventions:   Drug: Pioglitazone;   Drug: Rosiglitazone
Sponsors:   Takeda;   Eli Lilly and Company
Completed

Wed, 31 May 2006 12:00:00 EDT

24-Hour Glycemia: Rosiglitazone Versus Glimepiride In Type 2 Diabetes

Condition:   Non-Insulin-Dependent Diabetes Mellitus
Interventions:   Drug: rosiglitazone-metformin fixed dose combination;   Drug: metformin + glimepiride
Sponsor:   GlaxoSmithKline
Completed

Thu, 27 Apr 2006 12:00:00 EDT

Effect of Rosiglitazone

Condition:   Healthy
Intervention:   Drug: rosiglitazone
Sponsor:   University Hospital, Montpellier
Completed

Wed, 01 Feb 2006 12:00:00 EST

A Study Of BRL49653C For The Treatment Of Type 2 Diabetes (Combination Therapy With Sulfonyl Urea) -With Placebo Study

Condition:   Diabetes Mellitus, Type 2
Intervention:   Drug: Rosiglitazone (BRL49653C)
Sponsor:   GlaxoSmithKline
Completed

Thu, 08 Feb 2007 12:00:00 EST

BRL49653C In Type 2 Diabetes -Comparison Study With Pioglitazone And Placebo By Monotherapy-

Condition:   Diabetes Mellitus, Type 2
Intervention:   Drug: Rosiglitazone
Sponsor:   GlaxoSmithKline
Completed

Mon, 27 Feb 2006 12:00:00 EST

Effect Of Rosiglitazone On Carotid Intima Media Thickness In Patients With Insulin Resistance Syndrome And/Or Type 2 Diabetes

Condition:   Diabetes Mellitus, Type 2
Intervention:   Drug: Rosiglitazone
Sponsor:   GlaxoSmithKline
Completed

Fri, 24 Mar 2006 12:00:00 EST

Rosiglitazone (Extended Release Tablets) As Adjunctive Therapy In Subjects With Mild To Moderate Alzheimer's Disease

Condition:   Alzheimer's Disease
Interventions:   Drug: Rosiglitazone Extended Release 2mg;   Drug: Rosiglitazone Extended Release 8mg;   Other: Placebo
Sponsor:   GlaxoSmithKline
Completed

Tue, 04 Jul 2006 12:00:00 EDT

Rosiglitazone Versus Rosiglitazone and Metformin Versus Rosiglitazone and Avandia in the Treatment of Nonalcoholic Steatohepatitis (NASH)

Conditions:   Nonalcoholic Steatohepatitis;   Nonalcoholic Fatty Liver Disease
Interventions:   Drug: avandia;   Drug: metformin;   Drug: losartan
Sponsor:   Brooke Army Medical Center
Unknown status

Tue, 17 Jun 2008 12:00:00 EDT

Effects Of Rosiglitazone (Extended Release Tablets) On Cerebral Glucose Utilisation And Cognition Alzheimers Disease

Condition:   Alzheimer's Disease
Interventions:   Drug: Rosiglitazone XR (extended release) oral tablets;   Drug: Placebo
Sponsor:   GlaxoSmithKline
Terminated

Thu, 08 Jun 2006 12:00:00 EDT

A Study to Assess the Effect Tasimelteon on the Cytochrome P450 3A4 and 2C8 Enzymes in Healthy Subjects

Condition:   Healthy Volunteers
Interventions:   Drug: Tasimelteon;   Drug: Rosiglitazone;   Drug: Midazolam
Sponsor:   Vanda Pharmaceuticals
Completed

Tue, 26 Jul 2011 12:00:00 EDT

Effects of Rosiglitazone on Renal Hemodynamics and Proteinuria of Type 2 Diabetic Patients With Renal Insufficiency Due to Overt Diabetic Nephropathy

Conditions:   Type 2 Diabetes;   Overt Diabetic Nephropathy
Interventions:   Drug: Rosiglitazone;   Drug: Placebo
Sponsor:   Technische Universität Dresden
Completed

Thu, 11 May 2006 12:00:00 EDT

Rosiglitazone Therapy In The Prevention Of Coronary Artery Disease In Patients With Impaired Glucose Tolerance

Condition:   Impaired Glucose Tolerance
Interventions:   Drug: Rosiglitazone;   Drug: Placebo
Sponsors:   Denver Research Institute;   GlaxoSmithKline
Unknown status

Tue, 12 Aug 2008 12:00:00 EDT

Growth Hormone and/or Rosiglitazone for HIV-Associated Increased Abdominal Fat and Insulin Resistance

Conditions:   HIV-Associated Lipodystrophy Syndrome;   Insulin Resistance;   HIV Infections;   Metabolic Syndrome X;   Body Weight Changes
Interventions:   Drug: Rosiglitazone;   Drug: Recombinant human growth hormone + rosiglitazone
Sponsors:   Weill Medical College of Cornell University;   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Completed

Mon, 15 Aug 2005 12:00:00 EDT

Rosiglitazone and Insulin Resistance in Renally Impaired Patients

Conditions:   Chronic Kidney Disease;   Insulin Resistance
Intervention:   Drug: rosiglitazone
Sponsor:   Leiden University Medical Center
Terminated

Tue, 27 Mar 2007 12:00:00 EDT

Efficacy and Safety Study of Rosiglitazone/Metformin Therapy vs Rosiglitazone and Metformin in Type 2 Diabetes Subjects

Condition:   Diabetes Mellitus, Type 2
Intervention:   Drug: rosiglitazone maleate/metformin hydrochloride
Sponsor:   GlaxoSmithKline
Completed

Wed, 11 Jul 2007 12:00:00 EDT

Effect of Thiazolidinedione Treatment Vascular Risk Markers

Conditions:   Diabetes Mellitus, Type 2;   Vascular Diseases
Interventions:   Drug: Rosiglitazone;   Drug: Pioglitazone
Sponsor:   University of Arkansas
Completed

Wed, 12 Dec 2007 12:00:00 EST

Effects of Rosiglitazone on Serum Ghrelin and Peptide YY Levels

Conditions:   Type 2 Diabetes Mellitus;   Obesity
Intervention:   Drug: rosiglitazone
Sponsor:   Baskent University
Completed

Wed, 29 Aug 2007 12:00:00 EDT

Study In Patients With Insulin Resistance

Condition:   Insulin Resistance
Intervention:   Drug: Avandia
Sponsor:   GlaxoSmithKline
Completed

Tue, 20 Sep 2005 12:00:00 EDT

Effect of Rosiglitazone in Nondiabetic Patients With the Metabolic Syndrome

Conditions:   Metabolic Syndrome;   Insulin Resistance
Intervention:   Drug: Rosiglitazone
Sponsor:   University of Colorado, Denver
Completed

Tue, 15 Aug 2006 12:00:00 EDT

Vascular Effects of Rosiglitazone Versus Glyburide in Type 2 Diabetic Patients

Condition:   Type 2 Diabetes Mellitus
Interventions:   Drug: rosiglitazone;   Drug: glyburide
Sponsors:   St. Paul Heart Clinic;   GlaxoSmithKline
Completed

Mon, 25 Jul 2005 12:00:00 EDT

Use of Rosiglitazone in the Treatment of Endometriosis

Condition:   Endometriosis
Intervention:   Drug: Rosiglitazone
Sponsors:   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD);   Berlex Foundation
Terminated

Fri, 24 Jun 2005 12:00:00 EDT

Rosiglitazone In Subjects With Type 2 Diabetes Mellitus Who Are Inadequately Controlled On Insulin

Condition:   Diabetes Mellitus, Type 2
Intervention:   Drug: rosiglitazone
Sponsor:   GlaxoSmithKline
Completed

Wed, 24 May 2006 12:00:00 EDT

Fluid Retention in Rosiglitazone Treated Subjects With Autonomic Neuropathy.

Condition:   Neuropathy, Diabetic
Intervention:   Drug: rosiglitazone
Sponsor:   GlaxoSmithKline
Completed

Wed, 17 Jan 2007 12:00:00 EST

Anti-Inflammatory Effects of Rosiglitazone in Patients With Stage 4 and 5 Chronic Kidney Disease

Conditions:   Chronic Kidney Disease;   Inflammation
Intervention:   Drug: rosiglitazone
Sponsor:   Leiden University Medical Center
Withdrawn

Thu, 15 Sep 2005 12:00:00 EDT

RECORD: Rosiglitazone Evaluated for Cardiac Outcomes and Regulation of Glycaemia in Diabetes

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Rosiglitazone;   Drug: Sulfonylurea;   Drug: Metformin
Sponsor:   GlaxoSmithKline
Completed

Fri, 22 Sep 2006 12:00:00 EDT

Compare the Pharmacokinetics of Omeprazole, Rosiglitazone, and Desipramine When Administered With Avanafil in Healthy Male Subjects

Condition:   Erectile Dysfunction
Interventions:   Drug: Omeprazole;   Drug: Rosiglitazone;   Drug: Desipramine
Sponsor:   VIVUS, Inc.
Completed

Thu, 11 Aug 2011 12:00:00 EDT

PK, Dose Proportionality, Food Effect And Repeat Dose Study Of Rosiglitazone XR In Healthy Volunteers

Condition:   Alzheimer's Disease
Intervention:   Drug: Rosiglitazone XR
Sponsor:   GlaxoSmithKline
Completed

Wed, 13 Aug 2008 12:00:00 EDT

Rosiglitazone in Treating Patients With Locoregionally Extensive or Metastatic Thyroid Cancer

Condition:   Head and Neck Cancer
Intervention:   Drug: rosiglitazone maleate
Sponsors:   University of California, San Francisco;   National Cancer Institute (NCI)
Unknown status

Thu, 09 Dec 2004 12:00:00 EST

The Anti-Inflammatory And Metabolic Effects Of Rosiglitazone In Subjects With Rheumatoid Arthritis

Condition:   Arthritis, Rheumatoid
Intervention:   Drug: rosiglitazone XR
Sponsor:   GlaxoSmithKline
Completed

Fri, 22 Sep 2006 12:00:00 EDT

Rosiglitazone Versus a Sulfonylurea On Progression Of Atherosclerosis In Patients With Heart Disease And Type 2 Diabetes

Condition:   Atherosclerosis
Interventions:   Drug: Glipizide;   Drug: rosiglitazone maleate
Sponsor:   GlaxoSmithKline
Completed

Fri, 01 Jul 2005 12:00:00 EDT

A Study of Pharmacokinetic Drug Interaction Study of the Hedgehog Pathway Inhibitor GDC-0449 in Combination With Rosiglitazone or Combined Oral Contraceptive in Patients With Locally Advanced or Metastatic Solid Tumors That Are Refractory to Standard Therapy or for Whom No Standard Therapy Exists

Condition:   Solid Cancers
Interventions:   Drug: Vismodegib;   Drug: Rosiglitazone;   Drug: Norethindrone/ethinyl estradiol
Sponsor:   Genentech, Inc.
Completed

Mon, 27 Sep 2010 12:00:00 EDT

The Effect of Pioglitazone and Rosiglitazone on Atherosclerotic and Inflammatory Markers in Patients With Metabolic Syndrome

Condition:   Metabolic Syndrome
Intervention:   Drug: Pioglitazone, Rosiglitazone
Sponsor:   Korea University Anam Hospital
Completed

Fri, 14 Apr 2006 12:00:00 EDT

Rosiglitazone (Extended Release Tablets) As Adjunctive Therapy For Subjects With Mild To Moderate Alzheimer's Disease

Condition:   Alzheimer's Disease
Interventions:   Drug: Rosiglitazone Extended Release 2mg;   Drug: Rosiglitazone Extended Release 8mg;   Other: Placebo;   Other: Donepezil
Sponsor:   GlaxoSmithKline
Completed

Tue, 04 Jul 2006 12:00:00 EDT

Diabetes Study With Rosiglitazone Monotherapy Versus Metformin Or Glyburide/Glibenclamide

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Rosiglitazone;   Drug: glyburide;   Drug: metformin
Sponsor:   GlaxoSmithKline
Completed

Thu, 19 Jan 2006 12:00:00 EST

An Open Label, Multi-centre, Non-interventional Post-marketing Surveillance to Monitor the Safety and/or Efficacy of AVANDAMET Between June 2004 and January 2010

Condition:   Diabetes Mellitus, Type 2
Intervention:   Drug: Administration of rosiglitazone/metformin
Sponsor:   GlaxoSmithKline
Completed

Fri, 11 Feb 2011 12:00:00 EST

Examining the Effect of Different Diuretics on Fluid Retention in Diabetics Treated With Rosiglitazone.

Condition:   Diabetes Mellitus
Interventions:   Drug: Rosiglitazone;   Drug: spironolactone;   Drug: hydrochlorothiazide;   Drug: frusemide
Sponsor:   GlaxoSmithKline
Completed

Fri, 24 Mar 2006 12:00:00 EST

Dietary Fatty Acids as Complementary Therapy in Type 2 Diabetes Mellitus

Condition:   Type 2 Diabetes Mellitus
Interventions:   Drug: Rosiglitazone (Avandia) OR other diabetes medication currently prescribed to participant;   Dietary Supplement: conjugated linoleic acid (CLA)
Sponsors:   Ohio State University;   National Center for Complementary and Integrative Health (NCCIH);   GlaxoSmithKline;   Bunge Loders Croklaan;   LifeScan
Completed

Wed, 06 Feb 2008 12:00:00 EST

Rosiglitazone-Induced Weight Gain

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Rosiglitazone;   Behavioral: dietary recommendation for weight maintenance
Sponsors:   Stanford University;   GlaxoSmithKline
Terminated

Fri, 23 Sep 2005 12:00:00 EDT

The Influence of Rosiglitazone on the Diuretic Effect of Furosemide and Amiloride

Condition:   Insulin Resistance
Interventions:   Drug: Rosiglitazone versus placebo;   Drug: response (sodium excretion) to amiloride infusion;   Drug: response (sodium excretion) to furosemide infusion
Sponsor:   Radboud University
Completed

Thu, 02 Feb 2006 12:00:00 EST

Rosiglitazone-Metformin Combination Versus Metformin-Sulfonylurea Combination On Beta-Cell Function In Type 2 Diabetes

Condition:   Type 2 Diabetes Mellitus
Interventions:   Drug: rosiglitazone-metformin;   Drug: Metformin;   Drug: metformin+ gliclazide
Sponsor:   GlaxoSmithKline
Completed

Tue, 22 Aug 2006 12:00:00 EDT

Role of Insulin Action and Free Fatty Acids in Hyperandrogenism of Women With Polycystic Ovary Syndrome

Condition:   Polycystic Ovary Syndrome
Interventions:   Drug: Rosiglitazone;   Drug: Acarbose
Sponsors:   Jean-Patrice Baillargeon;   Canadian Institutes of Health Research (CIHR)
Suspended

Wed, 25 Nov 2009 12:00:00 EST

Safety and Efficacy Study of Adjunctive Rosiglitazone in the Treatment of Uncomplicated Falciparum Malaria

Condition:   Falciparum Malaria
Interventions:   Drug: Rosiglitazone;   Drug: Placebo
Sponsors:   Mahidol University;   McLaughlin-Rotman Center for Global Health, University of Toronto
Completed

Thu, 08 Sep 2005 12:00:00 EDT

Prevention of Corticosteroid-induced Glucose Intolerance

Condition:   Glucose Intolerance
Intervention:   Drug: Rosiglitazone
Sponsor:   Hadassah Medical Organization
Unknown status

Tue, 18 Oct 2005 12:00:00 EDT

Rosiglitazone Versus Theophylline in Asthmatic Smokers

Condition:   Asthma
Interventions:   Drug: rosiglitazone;   Drug: theophylline;   Drug: beclomethasone;   Drug: inhaled beclomethasone and oral theophylline
Sponsors:   University of Glasgow;   GlaxoSmithKline;   Chest, Heart and Stroke Association Scotland;   Chief Scientist Office of the Scottish Government
Completed

Wed, 13 Jul 2005 12:00:00 EDT

The Study of Atherosclerosis With Ramipril and Rosiglitazone

Conditions:   Atherosclerosis;   Impaired Glucose Tolerance;   Isolated Impaired Fasting Glucose;   Cardiovascular Disease
Interventions:   Drug: Ramipril;   Drug: Rosiglitazone
Sponsors:   Gerstein, Hertzel, MD;   Heart and Stroke Foundation of Ontario
Completed

Thu, 01 Sep 2005 12:00:00 EDT

The DREAM (Diabetes Reduction Assessment With Ramipril and Rosiglitazone Medication) Trial

Conditions:   Impaired Glucose Tolerance;   Cardiovascular Disease;   Glucose Metabolism Disorders
Interventions:   Drug: Ramipril;   Drug: Rosiglitazone
Sponsors:   Gerstein, Hertzel, MD;   Canadian Institutes of Health Research (CIHR);   Aventis Pharmaceuticals;   GlaxoSmithKline;   King Pharmaceuticals is now a wholly owned subsidiary of Pfizer;   Wyeth is now a wholly owned subsidiary of Pfizer
Completed

Mon, 08 Nov 2004 12:00:00 EST

A Methodological Study To Evaluate The Effects of Single Oral Doses Of Pioglitazone 45 mg And Rosiglitazone 8 mg On Sodium Balance In Healthy Male Volunteers

Condition:   Type 2 Diabetes Mellitus
Interventions:   Drug: pioglitazone/rosiglitazone/placebo;   Drug: rosiglitazone/pioglitazone/placebo;   Drug: placebo/pioglitazone/rosiglitazone;   Drug: pioglitazone/placebo/rosiglitazone;   Drug: rosiglitazone/placebo/pioglitazone;   Drug: placebo/rosiglitazone/pioglitazone
Sponsor:   Solvay Pharmaceuticals
Completed

Wed, 17 Mar 2010 12:00:00 EDT

Insulin Resistance, Polycystic Ovary Syndrome, and Bone Research Study

Condition:   Polycystic Ovary Syndrome
Interventions:   Drug: rosiglitazone;   Drug: drospirenone/ethinyl estradiol
Sponsors:   Silva Arslanian;   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Completed

Fri, 21 Mar 2008 12:00:00 EDT

Predictive Markers of Glitazone Efficacy in Diabetic Patients - Pilot Study

Condition:   Diabetes Mellitus, Type 2
Intervention:   Drug: Rosiglitazone
Sponsors:   Imperial College London;   GlaxoSmithKline
Withdrawn

Fri, 01 Jun 2007 12:00:00 EDT

Safety/Efficacy of Sitagliptin in Patient w/ Type 2 Diabetes (0431-801)

Condition:   Type 2 Diabetes Mellitus
Interventions:   Drug: Sitagliptin;   Drug: Comparator: Rosiglitazone;   Drug: Comparator: Placebo;   Drug: Comparator: Metformin
Sponsor:   Merck Sharp & Dohme Corp.
Completed

Wed, 10 Oct 2007 12:00:00 EDT

Beta Cell Function Tests Over Time In Patients With T2dm Randomized To Metformin Or Rosiglitazone

Condition:   Type 2 Diabetes Mellitus
Interventions:   Drug: Rosiglitazone;   Drug: Metformin
Sponsor:   Pfizer
Terminated

Fri, 27 Jan 2006 12:00:00 EST

Metformin and Rosiglitazone, Alone or in Combination, in HIV-Infected Patients With Insulin and Fat Abnormalities

Conditions:   HIV Infections;   Lipodystrophy;   Hyperinsulinemia
Interventions:   Drug: Metformin hydrochloride;   Drug: Rosiglitazone maleate
Sponsor:   National Institute of Allergy and Infectious Diseases (NIAID)
Completed

Fri, 31 Aug 2001 12:00:00 EDT

Rosiglitazone Versus Placebo in Chronic Stable Angina

Conditions:   Angina Pectoris;   Metabolic Syndrome X
Intervention:   Drug: Rosiglitazone
Sponsors:   University of Glasgow;   British Heart Foundation;   GlaxoSmithKline
Terminated

Fri, 23 Sep 2005 12:00:00 EDT

Study In Postmenopausal Women With Type 2 Diabetes Looking At Approved Diabetes Drugs And How They Affect Bone Health

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Rosiglitazone;   Drug: Metformin
Sponsor:   GlaxoSmithKline
Completed

Mon, 19 May 2008 12:00:00 EDT

Effect of Rosiglitazone on Peritoneal Cytokines in Women With Endometriosis

Condition:   Endometriosis
Intervention:   Drug: Rosiglitazone
Sponsor:   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Withdrawn

Thu, 21 Jul 2005 12:00:00 EDT

Rosiglitazone to Treat Patients With Heart Failure and Glucose Intolerance or Type II Diabetes

Condition:   Congestive Heart Failure
Interventions:   Drug: Avandia (Rosiglitazone);   Drug: Avanclia (Rosiqlitazone)
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Completed

Fri, 11 Jul 2003 12:00:00 EDT

Fenofibrate and Metformin Fixed Combination vs Rosiglitazone - FAME ROSI

Conditions:   Dyslipidemia;   Glucose Metabolism Disorder
Interventions:   Drug: fenofibrate (F) + metformin (M) hydrochloride fixed combination;   Drug: Rosiglitazone
Sponsor:   Solvay Pharmaceuticals
Terminated

Wed, 09 Aug 2006 12:00:00 EDT

Anti-PD-1 mAb Plus Metabolic Modulator in Solid Tumor Malignancies

Conditions:   Melanoma;   Renal Cell Carcinoma;   NSCLC;   Hepatocellular Carcinoma;   Urothelial Cancer;   Gastric Adenocarcinoma;   HNSCC;   Esophageal Adenocarcinoma;   Microsatellite Instability-High Solid Malignant Tumor
Interventions:   Drug: Nivolumab or Pembrolizumab (dependent upon approved indication);   Drug: Metformin;   Drug: Rosiglitazone
Sponsor:   Dan Zandberg
Recruiting

Thu, 03 Oct 2019 12:00:00 EDT

The Pharmacokinetic Interaction Between Oral Casopitant and Oral Dolasetron, Granisetron or Rosiglitazone in Subjects

Condition:   Nausea and Vomiting, Chemotherapy-Induced
Interventions:   Drug: casopitant;   Drug: dolasetron;   Drug: granisetron;   Drug: rosiglitazone
Sponsor:   GlaxoSmithKline
Completed

Mon, 06 Aug 2007 12:00:00 EDT

Efficacy and Safety In Poorly Controlled Type 2 Diabetics

Condition:   Diabetes Mellitus, Type 2
Intervention:   Drug: rosiglitazone
Sponsor:   GlaxoSmithKline
Completed

Fri, 30 Aug 2002 12:00:00 EDT

Evaluation of the Duration of Oral Combination Therapy in Type 2 Diabetes, Prior to the Initiation of Insulin in the UK

Condition:   Diabetes Mellitus, Type 2
Intervention:   Drug: Rosiglitazone
Sponsor:   GlaxoSmithKline
Completed

Fri, 16 Oct 2009 12:00:00 EDT

Glitazones and Endothelial Function (GATE)

Condition:   Diabetes Mellitus
Intervention:   Drug: rosiglitazone/placebo
Sponsors:   University of Calgary;   GlaxoSmithKline
Terminated

Tue, 20 Sep 2005 12:00:00 EDT


A First Time in Human Study in Healthy Volunteers to Investigate a New Medicine to Treat Malaria

Condition:   Malaria
Intervention:   Drug: GSK932121; Rosiglitazone; Rosuvastatin
Sponsor:   GlaxoSmithKline
Terminated

Fri, 19 Dec 2008 12:00:00 EST

To Investigate the Effect of Rosiglitazone and Ramipril on Pre-clinical Vasculopathy in Diabetes and IGT Patients

Conditions:   Diabetes;   Impaired Glucose Tolerance
Interventions:   Drug: Rosiglitazone;   Drug: Ramipril
Sponsors:   Universiti Sains Malaysia;   Ministry of Health, Malaysia
Completed

Thu, 21 Jun 2007 12:00:00 EDT

Markers and Mechanisms of Vascular Disease in Type II Diabetes

Condition:   Type 2 Diabetes Mellitus
Intervention:   Drug: Rosiglitazone
Sponsors:   US Department of Veterans Affairs;   American Diabetes Association
Completed

Mon, 21 Nov 2005 12:00:00 EST

Underlying Abnormalities in Fat and Muscle Leading to Lipodystrophy Syndrome

Conditions:   HIV Infections;   Lipodystrophy;   Insulin Resistance
Intervention:   Drug: Avandia administration for 6-12 weeks
Sponsor:   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Completed

Wed, 23 Aug 2000 12:00:00 EDT

A Study To Evaluate The Safety And Efficacy Of An Investigational Diabetes Drug In Poorly Controlled Type II Diabetics

Condition:   Diabetes Mellitus, Type 2
Intervention:   Drug: rosiglitazone/metformin
Sponsor:   GlaxoSmithKline
Completed

Fri, 05 Sep 2003 12:00:00 EDT

Celecoxib and Rosiglitazone in Treating Patients Who Are Undergoing Cystoscopic Surveillance for Early-Stage Noninvasive Carcinoma of the Bladder or Radical Cystectomy for Muscle-Invasive Carcinoma of the Bladder

Condition:   Bladder Cancer
Interventions:   Drug: celecoxib;   Drug: rosiglitazone maleate;   Procedure: conventional surgery;   Procedure: neoadjuvant therapy
Sponsors:   Fox Chase Cancer Center;   National Cancer Institute (NCI)
Withdrawn

Fri, 11 Jun 2004 12:00:00 EDT

Insulin Resistance in Non-alcoholic Fatty Liver Disease

Conditions:   Fatty Liver;   Insulin Resistance
Interventions:   Drug: rosiglitazone;   Drug: fenofibrate;   Drug: placebo for rosiglitazone;   Drug: placebo for fenofibrate
Sponsor:   US Department of Veterans Affairs
Terminated

Fri, 11 Nov 2005 12:00:00 EST

A Lifestyle and Combination Medication Therapy Diabetes Prevention Study

Conditions:   Impaired Glucose Tolerance;   Diabetes
Intervention:   Drug: Avandamet [Rosiglitazone 2mg/Metformin 500mg] BID
Sponsors:   Samuel Lunenfeld Research Institute, Mount Sinai Hospital;   University of Western Ontario, Canada
Completed

Fri, 01 Jul 2005 12:00:00 EDT

The Impact of Obesity and Obesity Treatments on Breast Cancer

Condition:   Breast Cancer
Interventions:   Drug: Exemestane;   Drug: Avandamet
Sponsors:   M.D. Anderson Cancer Center;   Susan G. Komen Breast Cancer Foundation
Completed

Tue, 07 Jul 2009 12:00:00 EDT

Avandamet Bioequivalence Study Brazil - Fed Administration

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Rosiglitazone Maleate + Metformin 2 miligrams (mg) + 500 mg;   Drug: Rosiglitazone Maleate + Metformin 4 miligrams (mg) + 1000 mg
Sponsor:   GlaxoSmithKline
Completed

Fri, 08 Apr 2011 12:00:00 EDT

Drug Interaction Study With Atazanavir Administered With and Without Ritonavir and a Cytochrome P450 Substrate Rosiglitazone

Condition:   HIV Infections
Interventions:   Drug: Rosiglitazone maleate;   Drug: Atazanavir Sulphate;   Drug: Atazanavir Sulphate + Rosiglitazone maleate;   Drug: Atazanavir Sulphate + Ritonavir;   Drug: Atazanavir Sulphate + Ritonavir + Rosiglitazone maleate
Sponsor:   Bristol-Myers Squibb
Completed

Thu, 10 Aug 2006 12:00:00 EDT

Targeting Peroxisome Proliferator-activated Receptor-gamma in Peritoneal Dialysis Patients - Will it Reduce Inflammation, Atherosclerosis, Calcification and Improve Survival of Peritoneal Dialysis Patients?

Conditions:   Chronic Disease;   Kidney Diseases;   Cardiovascular Diseases
Intervention:   Drug: rosiglitazone
Sponsor:   Hospital Authority, Hong Kong
Unknown status

Thu, 16 Aug 2007 12:00:00 EDT

Ppar-Gamma EliminAtes Restenosis Longevity Study: PEARLS

Condition:   Metabolic Syndrome
Intervention:   Drug: rosiglitazone
Sponsors:   Medstar Health Research Institute;   GlaxoSmithKline
Terminated

Wed, 25 Apr 2007 12:00:00 EDT

Insulin, Neurogenetics and Memory in Alzheimer's Disease

Condition:   Alzheimer Disease
Intervention:   Drug: rosiglitazone
Sponsor:   US Department of Veterans Affairs
Completed

Thu, 05 Jul 2001 12:00:00 EDT

Defining the Role of Insulin Resistance in 'Idiopathic' Dilated Cardiomyopathy

Condition:   Dilated Cardiomyopathy
Intervention:   Drug: Rosiglitazone therapy
Sponsor:   Stanford University
Terminated

Fri, 27 Apr 2007 12:00:00 EDT

Glycemic Control and Complications in Diabetes Mellitus Type 2 (VADT)

Condition:   Type 2 Diabetes Mellitus
Interventions:   Drug: Insulin;   Drug: Glimepiride;   Drug: Rosiglitazone;   Drug: Metformin
Sponsors:   VA Office of Research and Development;   National Eye Institute (NEI);   SmithKline Beecham
Completed

Fri, 22 Mar 2002 12:00:00 EST

Effect of Repaglinide and Metformin Combination Tablet or Rosiglitazone and Metformin in Fixed Dose Combination on Blood Glucose Control in Patients With Type 2 Diabetes

Conditions:   Diabetes;   Diabetes Mellitus, Type 2
Interventions:   Drug: repaglinide and metformin combination tablet;   Drug: rosiglitazone and metformin combination tablet
Sponsor:   Novo Nordisk A/S
Completed

Wed, 15 Nov 2006 12:00:00 EST

Thiazolidinedione Intervention With Vitamin D Evaluation

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: pioglitazone;   Drug: rosiglitazone;   Drug: placebo;   Dietary Supplement: Vitamin D;   Dietary Supplement: Placebo
Sponsors:   GlaxoSmithKline;   Population Health Research Institute
Terminated

Mon, 13 Apr 2009 12:00:00 EDT

Study of VX-770 on Midazolam and Rosiglitazone and the Effect of Fluconazole on VX-770

Condition:   Cystic Fibrosis
Intervention:   Drug: VX-770
Sponsor:   Vertex Pharmaceuticals Incorporated
Completed

Tue, 02 Feb 2010 12:00:00 EST

BIIB014 Effects on the Pharmacokinetics (PK) of Rosiglitazone, Warfarin, and Midazolam

Condition:   Healthy
Interventions:   Drug: BIIB014;   Drug: Placebo
Sponsor:   Biogen
Completed

Fri, 20 Nov 2009 12:00:00 EST

Demonstrate Exubera Works As Well As Avandia When Added To Sulfonylurea + Metformin In Controlling Glucose

Condition:   Diabetes Mellitus
Intervention:   Drug: Inhaled insulin
Sponsors:   Pfizer;   Sanofi
Completed

Thu, 08 Sep 2005 12:00:00 EDT

Effects of Fatty Acid Delivery on Heart Metabolism and Function in Type 2 Diabetes (T2DM

Condition:   Diabetes Mellitus, Type II
Interventions:   Drug: Metformin;   Drug: Rosiglitazone;   Drug: Lovaza
Sponsor:   Washington University School of Medicine
Completed

Thu, 20 Dec 2007 12:00:00 EST

Free Fatty Acid-Induced Hypertension in Obese Subjects With Type 2 Diabetes

Conditions:   Type 2 Diabetes;   Hypertension
Interventions:   Drug: Rosiglitazone;   Drug: Normal saline 0.9%;   Drug: Intralipid 20%
Sponsors:   Emory University;   GlaxoSmithKline
Completed

Wed, 20 Aug 2008 12:00:00 EDT

AVANDAMET Versus Metformin For Type 2 Diabetes Mellitus

Condition:   Diabetes Mellitus, Type 2
Intervention:   Drug: rosiglitazone/metformin
Sponsor:   GlaxoSmithKline
Completed

Wed, 19 Oct 2005 12:00:00 EDT

Insulin Glargine v Rosiglitazone as add-on Therapy in Patients Failing Sulfonylurea and Metformin Combination Therapy

Condition:   Type 2 Diabetes Mellitus
Interventions:   Drug: insulin glargine;   Drug: rosiglitazone;   Drug: metformin
Sponsor:   Sanofi
Completed

Mon, 31 Jul 2006 12:00:00 EDT

Study Of AVANDAMET® With Or Without Insulin In Type II Diabetes Mellitus Patients. AVANDAMET® is a Registered Trademark of the GSK Group of Companies.

Condition:   Diabetes Mellitus, Type 2
Intervention:   Drug: Rosiglitazone/metformin
Sponsor:   GlaxoSmithKline
Completed

Fri, 03 Oct 2003 12:00:00 EDT

Study to Investigate the Interaction Between FG-4592 and Rosiglitazone in Healthy Adult Subjects

Condition:   Healthy Adult Subjects
Intervention:   Drug: FG-4592
Sponsor:   FibroGen
Completed

Mon, 20 Jun 2011 12:00:00 EDT

Effect of Liraglutide on Blood Glucose Control in Subjects With Type 2 Diabetes

Conditions:   Diabetes;   Diabetes Mellitus, Type 2
Interventions:   Drug: liraglutide;   Drug: rosiglitazone;   Drug: metformin
Sponsor:   Novo Nordisk A/S
Completed

Fri, 02 Jun 2006 12:00:00 EDT

BAY73-4506 Probe Substrate Study

Condition:   Neoplasms
Interventions:   Drug: Regorafenib (Stivarga, BAY73-4506);   Drug: Warfarin;   Drug: Omeprazole;   Drug: Midazolam;   Drug: Rosiglitazone
Sponsor:   Bayer
Completed

Tue, 01 Feb 2011 12:00:00 EST

Effect of Liraglutide on Blood Glucose Control in Subjects With Type 2 Diabetes

Conditions:   Diabetes;   Diabetes Mellitus, Type 2
Interventions:   Drug: liraglutide;   Drug: rosiglitazone;   Drug: glimepiride
Sponsor:   Novo Nordisk A/S
Completed

Wed, 26 Apr 2006 12:00:00 EDT

Pioglitazone to Treat Fatty Liver in Patients With HIV and Hepatitis C Infections

Conditions:   HIV;   Hepatitis C;   Liver Disease;   Fatty Liver;   Steatosis
Interventions:   Drug: Pioglitazone;   Drug: Placebo
Sponsor:   National Institute of Allergy and Infectious Diseases (NIAID)
Terminated

Wed, 27 Aug 2008 12:00:00 EDT

Efficacy and Safety of Inhaled Pre-prandial Human Insulin in Type 2 Diabetes

Conditions:   Diabetes;   Diabetes Mellitus, Type 2
Interventions:   Drug: rosiglitazone;   Drug: inhaled human insulin;   Drug: metformin
Sponsor:   Novo Nordisk A/S
Terminated

Thu, 06 Jul 2006 12:00:00 EDT

Safety and Efficacy of Inhaled Pre-prandial Human Insulin in Type 2 Diabetes

Conditions:   Diabetes;   Diabetes Mellitus, Type 2
Interventions:   Drug: rosiglitazone;   Drug: inhaled human insulin;   Drug: glimepiride
Sponsor:   Novo Nordisk A/S
Terminated

Fri, 23 Jun 2006 12:00:00 EDT

Metabolic Effects of Treatment in Patients With Recently Diagnosed Type 2 Diabetes

Condition:   Type 2 Diabetes Mellitus
Interventions:   Drug: rosiglitazone;   Drug: metformin;   Drug: Anti-diabetic medications
Sponsors:   Aristotle University Of Thessaloniki;   University of Athens
Completed

Thu, 07 Sep 2006 12:00:00 EDT

Rosiglitazone and Metformin: Outcomes Trial in Nondiabetic Patients With Stable Coronary Syndromes (Romance) Pilot Study

Condition:   Coronary Artery Disease
Intervention:   Drug: AVANDAMET
Sponsors:   Intermountain Health Care, Inc.;   GlaxoSmithKline
Terminated

Fri, 23 Jun 2006 12:00:00 EDT

Sitagliptin Metformin/PPARg Agonist Combination Therapy Add-on (0431-052)

Condition:   Type 2 Diabetes Mellitus
Interventions:   Drug: sitagliptin;   Drug: Comparator: Placebo;   Drug: rosiglitazone;   Drug: metformin;   Drug: glipizide
Sponsor:   Merck Sharp & Dohme Corp.
Completed

Tue, 11 Jul 2006 12:00:00 EDT

Evaluation of Rosiglitazone Anti-inflammatory Effect With FDG-PET Imaging

Condition:   Lung Inflammation
Interventions:   Drug: Zileuton;   Drug: Pioglitazone placebo;   Drug: Zileuton placebo;   Drug: Pioglitazone
Sponsors:   Washington University School of Medicine;   Doris Duke Charitable Foundation
Completed

Tue, 03 Aug 2010 12:00:00 EDT

Treatment Options for Type 2 Diabetes in Adolescents and Youth (TODAY)

Condition:   Diabetes Mellitus, Type II
Interventions:   Drug: Metformin;   Drug: Rosiglitazone;   Behavioral: Lifestyle Program
Sponsor:   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Completed

Mon, 12 Apr 2004 12:00:00 EDT

Rosiglitazone to Reverse Metabolic Defects in Diabetes

Conditions:   Diabetes Mellitus, Type II;   Insulin Resistance
Interventions:   Procedure: Exercise cardiopulmonary metabolic testing;   Procedure: Skeletal muscle biopsy;   Procedure: Brachial artery reactivity testing
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Completed

Mon, 25 Oct 2004 12:00:00 EDT

Effect of GSK376501 on CYP450 Activity in Healthy Adult Subjects

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: GSK376501;   Drug: Midazolam;   Drug: Rosiglitazone;   Drug: Flurbiprofen
Sponsor:   GlaxoSmithKline
Completed

Thu, 14 Feb 2008 12:00:00 EST

Effects of Rosiglitazone on Blood Vessels in Patients With High Blood Pressure and High Cholesterol

Conditions:   Hypercholesterolemia;   Hypertension
Intervention:  
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Completed

Tue, 10 Dec 2002 12:00:00 EST

Effect of Inhaled Pre-prandial Human Insulin on Blood Glucose Control in Type 2 Diabetes

Conditions:   Diabetes;   Diabetes Mellitus, Type 2
Interventions:   Drug: rosiglitazone;   Drug: inhaled human insulin;   Drug: metformin;   Drug: glimepiride
Sponsor:   Novo Nordisk A/S
Terminated

Fri, 26 Jan 2007 12:00:00 EST

Efficacy and Safety of Vildagliptin Compared to Rosiglitazone in Drug Naive Patients With Type 2 Diabetes

Condition:   Diabetes Mellitus, Type 2
Intervention:   Drug: vildagliptin
Sponsor:   Novartis Pharmaceuticals
Completed

Wed, 22 Dec 2004 12:00:00 EST

Extension to a Study on the Efficacy and Safety of Vildagliptin Compared to Rosiglitazone in Drug Naive Patients With Type 2 Diabetes

Condition:   Diabetes Mellitus, Type 2
Intervention:   Drug: vildagliptin
Sponsor:   Novartis
Completed

Tue, 30 Aug 2005 12:00:00 EDT

Pioglitazone Study of Triglyceride Changes in Subjects With Type 2 Diabetes After Conversion From Rosiglitazone.

Condition:   Diabetes Mellitus
Intervention:   Drug: Pioglitazone
Sponsor:   Takeda
Completed

Tue, 06 May 2008 12:00:00 EDT

A Study To Demonstrate The Bioequivalence Of Rosiglitazone XR (BRL-049653) 8mgs XR Manufactured At Two Different Sites.

Condition:   Alzheimer's Disease
Intervention:   Drug: RSG XR
Sponsor:   GlaxoSmithKline
Completed

Thu, 03 May 2007 12:00:00 EDT

Safety and Efficacy of Nateglinide in Patients With Type 2 Diabetes Already Taking Insulin Glargine, Metformin and/or Pioglitazone or Rosiglitazone

Condition:   Type 2 Diabetes
Intervention:   Drug: Nateglinide
Sponsor:   Novartis Pharmaceuticals
Completed

Wed, 22 Nov 2006 12:00:00 EST

A Placebo-controlled Study to Investigate the Safety, and Pharmacokinetics of Oral GSK626616AC in Healthy Subjects

Conditions:   Healthy Subjects;   Anaemia
Interventions:   Drug: GSK626616, placebo, midazolam;   Drug: omeprazole, caffeine, flurbiprofen, rosiglitazone
Sponsor:   GlaxoSmithKline
Completed

Mon, 05 Mar 2007 12:00:00 EST

Safety and Efficacy of Vildagliptin vs. Thiazolidinedione as add-on Therapy to Metformin in Patients With Type 2 Diabetes Not Controlled With Metformin Alone

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: vildagliptin;   Drug: thiazolidinedione (TZD)
Sponsor:   Novartis Pharmaceuticals
Completed

Mon, 06 Nov 2006 12:00:00 EST

Effect of Pioglitazone on Left Ventricular Diastolic Function in Type 2 Diabetes Mellitus

Condition:   Type 2 Diabetes Mellitus
Interventions:   Drug: Pioglitazone (Actos);   Drug: Anti-diabetic agent other than pioglitazone or rosiglitazone
Sponsor:   Texas Tech University Health Sciences Center
Withdrawn

Tue, 04 Oct 2005 12:00:00 EDT

Efficacy and Safety of Dapagliflozin in Combination With Glimepiride (a Sulphonylurea) in Type 2 Diabetes Patients

Condition:   Type 2 Diabetes
Interventions:   Drug: dapagliflozin;   Drug: Glimepiride;   Drug: metformin hydrochloride;   Drug: pioglitazone hydrochloride;   Drug: Rosiglitazone
Sponsors:   AstraZeneca;   Bristol-Myers Squibb
Completed

Tue, 20 May 2008 12:00:00 EDT

Endothelial Dysfunction as a Risk Factor in HIV Study

Condition:   HIV Infections
Interventions:   Drug: Pravastatin;   Drug: Gemfibrozil;   Drug: Rosiglitazone
Sponsor:   National Institutes of Health Clinical Center (CC)
Completed

Fri, 07 Jun 2002 12:00:00 EDT

Drug Interaction Study Between AZD3480 and Cytochrome P450

Conditions:   Metabolism;   Alzheimer's Disease
Interventions:   Drug: AZD3480;   Drug: Placebo;   Drug: Cocktail mix (Caffeine, Bupropion, Rosiglitazone, Omeprazole, Midazolam, Bilirubin)
Sponsor:   AstraZeneca
Completed

Fri, 06 Jun 2008 12:00:00 EDT

Diagnosis and Therapy of Vulnerable Atherosclerotic Plaque

Conditions:   Carotid Atherosclerosis;   Stroke;   Type 2 Diabetes;   Metabolic Syndrome
Interventions:   Drug: atorvastatin;   Drug: rimonabant;   Drug: rosiglitazone;   Drug: metformin
Sponsor:   Aristotle University Of Thessaloniki
Completed

Fri, 14 Mar 2008 12:00:00 EDT

A Study Assessing Saxagliptin Treatment in Type 2 Diabetic Subjects Who Are Not Controlled With TZD Therapy Alone

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Saxagliptin;   Drug: Placebo;   Drug: pioglitazone;   Drug: rosiglitazone;   Drug: metformin
Sponsor:   AstraZeneca
Completed

Fri, 24 Feb 2006 12:00:00 EST

QTc Study of Rosi XR in Healthy Volunteers

Condition:   Alzheimer's Disease
Interventions:   Drug: Rosi XR;   Other: Placebo;   Drug: Moxifloxacin
Sponsor:   GlaxoSmithKline
Withdrawn

Mon, 20 Apr 2009 12:00:00 EDT

South Danish Diabetes Study: Evaluation of the Antidiabetic Treatment of Type 2 Diabetes Mellitus

Condition:   Type 2 Diabetes Mellitus
Interventions:   Drug: Insulin Aspart;   Drug: Insulin NPH;   Drug: Metformin;   Drug: Rosiglitazone
Sponsor:   Odense University Hospital
Completed

Thu, 21 Jul 2005 12:00:00 EDT

Randomized Controlled Trial of Insulin Versus Tablets for Latent Autoimmune Diabetes in Adults (LADA)

Condition:   Latent Autoimmune Diabetes in Adults LADA
Interventions:   Drug: NovoMix 30;   Drug: Tablet treatment
Sponsors:   Abertawe Bro Morgannwg University NHS Trust;   Novo Nordisk A/S
Unknown status

Tue, 21 Oct 2008 12:00:00 EDT

Medication in Early Diabetes (MED) Study

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Pioglitazone;   Drug: Metformin
Sponsor:   Menzies School of Health Research
Withdrawn

Wed, 21 Feb 2007 12:00:00 EST

Bioequivalence Study of SB797620 in Healthy Japanese Volunteers

Condition:   Healthy Subjects
Intervention:   Drug: SB797620
Sponsor:   GlaxoSmithKline
Withdrawn

Thu, 25 Oct 2007 12:00:00 EDT

Validation Study of Multiple Probe Compounds for Drug Interaction Evaluation

Condition:   Drug Interactions
Interventions:   Drug: Caffeine;   Drug: Rosiglitazone;   Drug: Flurbiprofen;   Drug: Omeprazole;   Drug: Dextromethorphan;   Drug: Midazolam;   Drug: Rosuvastatin;   Drug: Ketoconazole;   Drug: Fluconazole;   Drug: Rifampin
Sponsor:   GlaxoSmithKline
Completed

Mon, 24 Aug 2009 12:00:00 EDT

Cardiovascular (CV) Risk Evaluation In Type 2 Diabetes Subjects

Conditions:   Type 2 Diabetes Mellitus;   CV Risk
Intervention:  
Sponsor:   GlaxoSmithKline
Completed

Tue, 01 Apr 2008 12:00:00 EDT

A Type 2 Diabetes Study of the Longer-Term Glycemic Effect of AVANDAMET vs. Metformin

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: Avandamet 6 mg/1500 mg (ttd);   Drug: Avandamet 4 mg/1000 mg (ttd);   Drug: Avandamet 2 mg/500 mg (ttd);   Drug: Avandamet 8 mg/ 2000 mg (ttd);   Drug: Metformin 500 mg (ttd);   Drug: Metformin 1000 mg (ttd);   Drug: Metformin 1500 mg (ttd);   Drug: Metformin 2000 mg (ttd)
Sponsor:   GlaxoSmithKline
Completed

Wed, 11 Oct 2006 12:00:00 EDT

Effect of Intensive Therapy Associated With CSII on β-cell Function With Newly Diagnosed Type 2 Diabetes

Condition:   Type 2 Diabetes Mellitus
Intervention:   Drug: CSII,ALA,MET,RSG
Sponsor:   Sun Yat-sen University
Suspended

Wed, 29 Jul 2009 12:00:00 EDT

A Study of Different Doses of Sitagliptin (MK-0431) in Participants With Type 2 Diabetes Mellitus (MK-0431-014)

Condition:   Type II Diabetes Mellitus
Interventions:   Drug: Sitagliptin;   Drug: Placebo to sitagliptin;   Drug: Metformin;   Drug: Rescue
Sponsor:   Merck Sharp & Dohme Corp.
Completed

Mon, 04 Jun 2007 12:00:00 EDT

Effectiveness and Safety of Two Approaches to the Management of Type 2 Diabetes Mellitus in Australian Primary Care

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: INSULIN GLARGINE (HOE901);   Drug: Oral Anti Diabetics (OAD)
Sponsor:   Sanofi
Terminated

Fri, 31 Jul 2009 12:00:00 EDT

Action to Control Cardiovascular Risk in Diabetes (ACCORD)

Conditions:   Atherosclerosis;   Cardiovascular Diseases;   Hypercholesterolemia;   Hypertension;   Diabetes Mellitus, Type 2;   Diabetes Mellitus;   Coronary Disease
Interventions:   Drug: Anti-hyperglycemic Agents;   Drug: Anti-hypertensive Agents;   Drug: Blinded fenofibrate or placebo plus simvastatin
Sponsors:   National Heart, Lung, and Blood Institute (NHLBI);   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK);   National Institute on Aging (NIA);   National Eye Institute (NEI);   Centers for Disease Control and Prevention
Completed

Thu, 28 Oct 1999 12:00:00 EDT

Incretin-based Drugs and Pancreatic Cancer

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: DPP-4 inhibitors;   Drug: GLP-1 analogs;   Drug: Sulfonylureas;   Drug: Biguanides;   Drug: Thiazolidinediones;   Drug: Alpha-glucosidase inhibitors;   Drug: Meglitinides
Sponsors:   Canadian Network for Observational Drug Effect Studies, CNODES;   Drug Safety and Effectiveness Network, Canada;   Canadian Institutes of Health Research (CIHR)
Completed

Thu, 18 Jun 2015 12:00:00 EDT

Incretin-based Drugs and Acute Pancreatitis

Condition:   Diabetes Mellitus, Type 2
Interventions:   Drug: DPP-4 inhibitors;   Drug: GLP-1 analogs;   Drug: Insulins;   Drug: Biguanides;   Drug: Sulfonylureas;   Drug: Thiazolidinediones;   Drug: Alpha-glucosidase inhibitors;   Drug: Meglitinides
Sponsors:   Canadian Network for Observational Drug Effect Studies, CNODES;   Drug Safety and Effectiveness Network, Canada;   Canadian Institutes of Health Research (CIHR)
Completed

Fri, 19 Jun 2015 12:00:00 EDT

Incretin-based Drugs and the Risk of Heart Failure

Condition:   Type 2 Diabetes Mellitus
Interventions:   Drug: DPP-4 inhibitors;   Drug: GLP-1 analogs;   Drug: Insulins;   Drug: Biguanides;   Drug: Sulfonylureas;   Drug: Thiazolidinediones;   Drug: Alpha-glucosidase inhibitors;   Drug: Meglitinides
Sponsors:   Canadian Network for Observational Drug Effect Studies, CNODES;   Drug Safety and Effectiveness Network, Canada;   Canadian Institutes of Health Research (CIHR)
Completed

Thu, 28 May 2015 12:00:00 EDT

Fracture Risk With Thiazolidinediones

Conditions:   Fractures, Bone;   Type II Diabetes
Interventions:   Drug: TZD only (RSG or PIO or troglitazone);   Drug: TZD + spironolactone;   Drug: TZD + amiloride
Sponsor:   GlaxoSmithKline
Completed

Mon, 25 Jan 2010 12:00:00 EST

Sitagliptin (MK-0431) vs. Placebo in Patients With Inadequate Glycemic Control on Metformin With Pioglitazone (MK-0431-128)

Condition:   Type 2 Diabetes Mellitus
Interventions:   Drug: Sitagliptin;   Drug: Comparator: Placebo;   Drug: Pioglitazone;   Drug: Metformin;   Drug: Glipizide
Sponsor:   Merck Sharp & Dohme Corp.
Completed

Tue, 21 Apr 2009 12:00:00 EDT

Novel Therapies for Resistant FSGS (FONTII): Phase II Clinical Trial

Condition:   Focal Segmental Glomerulosclerosis
Interventions:   Drug: Adalimumab;   Drug: Lisinopril, losartan, and atorvastatin;   Drug: galactose
Sponsors:   NYU Langone Health;   University of Michigan;   The Cleveland Clinic;   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Completed

Wed, 24 Dec 2008 12:00:00 EST

24-week Treatment With Lixisenatide in Type 2 Diabetes Insufficiently Controlled With Metformin and Insulin Glargine

Condition:   Type 2 Diabetes Mellitus
Interventions:   Drug: Lixisenatide (AVE0010);   Drug: Placebo;   Drug: Insulin glargine;   Device: Pen auto-injector;   Drug: Metformin;   Drug: Thiazolidinedione (TZD)
Sponsor:   Sanofi
Completed

Fri, 11 Sep 2009 12:00:00 EDT

A Study for Comparison of Canagliflozin Versus Alternative Antihyperglycemic Treatments on Risk of Heart Failure Hospitalization and Amputation for Participants With Type 2 Diabetes Mellitus and the Subpopulation With Established Cardiovascular Disease

Conditions:   Diabetes Mellitus, Type 2;   Cardiovascular Diseases
Interventions:   Drug: Canagliflozin;   Drug: Empagliflozin;   Drug: Dapagliflozin;   Drug: Dipeptidyl Peptidase-4 (DPP-4) Inhibitors;   Drug: Glucagon-like Peptide-1 (GLP-1) Agonist;   Drug: Anti-hyperglycemic Agents (AHA);   Drug: Thiazolidinediones (TZD);   Drug: Sulfonylureas (SU);   Drug: Insulin
Sponsor:   Janssen Research & Development, LLC
Completed

Tue, 10 Apr 2018 12:00:00 EDT