Side effects of naprosyn (naproxen)


Naprosyn ( naproxen ) is a non-steroidal anti-inflammatory drug (NSAID) that is commonly used to treat pain and inflammatory conditions. It is also used to relieve menstrual cramps and reduce fever. The use of naprosine is approved by the United States Food and Drug Administration (FDA) for several cases. conditions including acute gout , bursitis , various forms of arthritis , tendonitis , and primary dysmenorrhea (painful periods) .

Naprosyn can be found over the counter under the Aleve brand, but is also available by prescription based on specific needs. Before taking a new medicine, talk with your healthcare provider to make sure it is safe and suitable for you.

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Common side effects

Many pain relievers have side effects, and Naprosin is no exception. However, drug side effects can vary in severity and likelihood, as people respond differently to drugs. Therefore, it can be difficult to determine if someone will experience side effects before taking the drug.

The most common side effects of naprosin include:

  • Stomach ache
  • Nausea
  • Acidity
  • Headache
  • Drowsiness or dizziness
  • Diarrhea
  • Constipation
  • Swelling
  • Gas
  • Nervousness
  • Acne
  • Blurry vision
  • Itching
  • Mouth ulcers
  • Excessive thirst
  • Tingling sensation in hands and feet.
  • Cold symptoms
  • Difficulty falling asleep or falling asleep at night.

These side effects are likely to be mild and short-lived, but if they persist or get worse, talk to your doctor to see if you should stop taking naprosine.

Serious side effects

The most serious side effects of the drug may require urgent medical attention. Whether someone suffers from these side effects depends entirely on how their body reacts to the medicine.

Serious side effects that can occur when using Naprosin include:

  • Easy bruising or bleeding
  • Difficulty or pain when swallowing
  • Ringing in the ears or other hearing changes
  • Changes in mental health or mood.
  • Changes in the amount of urine excreted throughout the day, which may indicate kidney problems.
  • Stiff neck with no known explanation
  • Vision changes
  • Heart failure symptoms such as swelling in the ankles and feet, fatigue, and sudden weight gain.
  • Stomach ulcers and gastrointestinal bleeding.
  • Renal insufficiency
  • Pancreatitis
  • Colitis
  • Seizures
  • Heart problems
  • Severe skin changes

There are other serious side effects that can cause liver failure or a severe allergic reaction . While taking this medicine, you should be on the lookout for symptoms of an allergic reaction, such as a rash and itching, severe dizziness, and shortness of breath. This is an emergency that requires immediate medical attention.

If you experience any symptoms that suggest liver failure, see your doctor immediately. These symptoms include:

  • Nausea and vomiting that does not go away.
  • Loss of appetite
  • Pain in the abdomen or abdomen
  • Jaundice or yellowing of the eyes and skin
  • Dark urine


Many medications come with a warning about possible side effects on their packaging. A specific caveat for Naprosyn is that this drug is not recommended for use in people with kidney problems. There are also warnings about other rare but life-threatening effects that should be considered before using this drug.

Black box warning

Naprosyn has a black box warning, which is the FDA's most serious warning of potential drug-related injuries and deaths. In rare cases, the use of naprosine can cause heart disease or high blood pressure in a person. It can also increase the risk of heart attack or stroke in those who have recently had or are about to have heart bypass surgery .

You should also avoid using this drug in people with stomach ulcers or bleeding, as the drug itself can cause or worsen these conditions. Naprosin has also been shown to cause fluid retention, which can lead to body edema. There is also an increased risk of cardiovascular events with long-term and chronic use of this drug.

Naprosin overdose can occur with excessive use of the drug for a short period of time. Symptoms of a naprosin overdose include:

  • Nausea
  • Threw up
  • Gastrointestinal bleeding
  • Kidney and liver failure.
  • Meningitis
  • Circulation
  • Death

Taking this medication only as directed by your healthcare professional will prevent an overdose.


Interaction with medications within the body and with other medications injected into the body can lead to adverse interactions. Naprosyn can cause more serious complications when combined with other medications. For example, when taking naprosine, alcohol should be avoided completely, as it can increase the risk of bleeding and stomach ulcers.

Other drug interactions that can occur are not serious, but they can reduce the effectiveness of the drug. Some specific foods that can interact with Naprosyn include:

Taking Naprosyn at the same time as blood thinners or antiplatelet drugs or other drugs that can cause bleeding, this can make this particular side effect worse. Interactions can also occur when naprosine is taken with other NSAIDs. If you are unsure about the ingredients in your medicine and are concerned about interactions, speak with your healthcare professional to clarify what you can and cannot take while taking naprosine.

Get the word of drug information

Although Naprosyn is generally safe and well tolerated, treatment with this drug should be approached with caution and under the guidance of your PCP. It is important to consider the possible side effects, the medications you are already taking, and your lifestyle to determine if this medication is right for you.

If you experience any side effects from naprosine, there may be another medicine that is better for you. Living with painful conditions like arthritis can be difficult, and in most cases, using NSAIDs like naprosin can help.

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