Full text biomedical articles

Sulfasalazine reduces placental secretion of antiangiogenic factors, up-regulates the secretion of placental growth factor and rescues endothelial dysfunction

Fiona C. Brownfoot, Natalie J. Hannan, Ping Cannon, Vi Nguyen, Roxanne Hastie, Laura J. Parry, Sevvandi Senadheera, Laura Tuohey, Stephen Tong, Tu'uhevaha J. Kaitu'u-Lino
EBioMedicine. 2019 Mar; 41: 636–648. Published online 2019 Feb 26. doi: 10.1016/j.ebiom.2019.02.013


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Aminosalicylates for induction of remission or response in Crohn's disease

Wee‐Chian Lim, Yongjun Wang, John K MacDonald, Stephen Hanauer
Cochrane Database Syst Rev. 2016 Jul; 2016(7): CD008870. Published online 2016 Jul 3. doi: 10.1002/14651858.CD008870.pub2


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Sulfasalazine attenuates tamoxifen-induced toxicity in human retinal pigment epithelial cells

Narae Hwang, Su Wol Chung
BMB Rep. 2020 May 31; 53(5): 284–289. Published online 2020 May 31. doi: 10.5483/BMBRep.2020.53.5.041


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Sulfasalazine induces mitochondrial dysfunction and renal injury

Hossein Niknahad, Reza Heidari, Roya Mohammadzadeh, Mohammad Mehdi Ommati, Forouzan Khodaei, Negar Azarpira, Narges Abdoli, Mahdi Zarei, Behnam Asadi, Maryam Rasti, Babak Shirazi Yeganeh, Vahid Taheri, Arastoo Saeedi, Asma Najibi
Ren Fail. 2017; 39(1): 745–753. Published online 2017 Dec 7. doi: 10.1080/0886022X.2017.1399908


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Sulfasalazine treatment can cause a positive effect on LPS-induced endotoxic rats

Burak Dik, Gonca Sonmez, Hatice Eser Faki, Emre Bahcivan
Exp Anim. 2018; 67(4): 403–412. Published online 2018 May 2. doi: 10.1538/expanim.18-0029


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Cystine/Glutamate Antiporter (xCT) Is Required for Chief Cell Plasticity After Gastric Injury

Anne R. Meyer, Amy C. Engevik, Spencer G. Willet, Janice A. Williams, Yong Zou, Pierre P. Massion, Jason C. Mills, Eunyoung Choi, James R. Goldenring
Cell Mol Gastroenterol Hepatol. 2019; 8(3): 379–405. Published online 2019 May 6. doi: 10.1016/j.jcmgh.2019.04.015


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Sulfasalazine‐Induced Agranulocytosis Is Associated With the Human Leukocyte Antigen Locus

Mia Wadelius, Niclas Eriksson, Reinhold Kreutz, Emmanuelle Bondon‐Guitton, Luisa Ibañez, Alfonso Carvajal, M. Isabel Lucena, Esther Sancho Ponce, Mariam Molokhia, Javier Martin, Tomas Axelsson, Hugo Kohnke, Qun‐Ying Yue, Patrik K.E. Magnusson, Mats Bengtsson, Pär Hallberg, on behalf of EuDAC
Clin Pharmacol Ther. 2018 May; 103(5): 843–853. Published online 2017 Sep 28. doi: 10.1002/cpt.805


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Promotion of Remyelination by Sulfasalazine in a Transgenic Zebrafish Model of Demyelination

Suhyun Kim, Yun-Il Lee, Ki-Young Chang, Dong-Won Lee, Sung Chun Cho, Young Wan Ha, Ji Eun Na, Im Joo Rhyu, Sang Chul Park, Hae-Chul Park
Mol Cells. 2015 Nov 30; 38(11): 1013–1021. Published online 2015 Nov 6. doi: 10.14348/molcells.2015.0246


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The association between NAT2 acetylator status and adverse drug reactions of sulfasalazine: a systematic review and meta-analysis

Jeong Yee, So Min Kim, Ji Min Han, Nari Lee, Ha Young Yoon, Hye Sun Gwak
Sci Rep. 2020; 10: 3658. Published online 2020 Feb 27. doi: 10.1038/s41598-020-60467-8


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Sulphasalazine inhibits macrophage activation: inhibitory effects on inducible nitric oxide synthase expression, interleukin-12 production and major histocompatibility complex II expression

György Haskó, Csaba Szabó, Zoltán H Németh, Edwin A Deitch
Immunology. 2001 Aug; 103(4): 473–478. doi: 10.1046/j.1365-2567.2001.01272.x


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Pharmacokinetic interaction study of sulphasalazine in healthy subjects and the impact of curcumin as an in vivo inhibitor of BCRP

Hiroyuki Kusuhara, Hidetoshi Furuie, Akihiro Inano, Akihiro Sunagawa, Saiko Yamada, Chunyong Wu, Shinya Fukizawa, Nozomi Morimoto, Ichiro Ieiri, Mariko Morishita, Kiminobu Sumita, Hiroshi Mayahara, Takuya Fujita, Kazuya Maeda, Yuichi Sugiyama
Br J Pharmacol. 2012 Jul; 166(6): 1793–1803. doi: 10.1111/j.1476-5381.2012.01887.x


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American Gastroenterological Association Technical Review on the Management of Mild to Moderate Ulcerative Colitis

Siddharth Singh, Joseph D. Feuerstein, David G. Binion, William J. Tremaine
Gastroenterology. Author manuscript; available in PMC 2020 Feb 1.
Published in final edited form as: Gastroenterology. 2019 Feb; 156(3): 769–808.e29. Published online 2018 Dec 18. doi: 10.1053/j.gastro.2018.12.008


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Sulfasalazine augments a pro‐inflammatory response in interleukin‐1β‐stimulated amniocytes and myocytes

Lynne Sykes, Kacie R. Thomson, Emily J. Boyce, Yun S. Lee, Zahirrah B. M. Rasheed, David A. MacIntyre, Tiong Ghee Teoh, Phillip R. Bennett
Immunology. 2015 Dec; 146(4): 630–644. Published online 2015 Nov 3. doi: 10.1111/imm.12534


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New approach of medicinal herbs and sulfasalazine mixture on ulcerative colitis induced by dextran sodium sulfate

Mi-Rae Shin, Hae-Jin Park, Bu-Il Seo, Seong-Soo Roh
World J Gastroenterol. 2020 Sep 21; 26(35): 5272–5286. Published online 2020 Sep 21. doi: 10.3748/wjg.v26.i35.5272


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Meningitis associated with sulphasalazine in a patient with Sjögren's syndrome and polyarthritis

P Merrin, I A Williams
Ann Rheum Dis. 1991 Sep; 50(9): 645–646. doi: 10.1136/ard.50.9.645


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Effect of Sulfasalazine on Inflammation and Endothelial Function in Patients with Established Coronary Artery Disease

Corey E Tabit, Monica Holbrook, Sherene M Shenouda, Mustali M Dohadwala, Michael E. Widlansky, Alissa A Frame, Brian H Kim, Mai-Ann Duess, Matthew A Kluge, Aaron Levit, John F. Keaney, Jr., Joseph A Vita, Naomi M Hamburg
Vasc Med. Author manuscript; available in PMC 2013 Apr 22.
Published in final edited form as: Vasc Med. 2012 Apr; 17(2): 101–107. doi: 10.1177/1358863X12440117


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Molecular mechanisms of sulfasalazine-induced T-cell apoptosis

Susanne Liptay, Simone Fulda, Marta Schanbacher, Soizic Bourteele, Karine F Ferri, Guido Kroemer, Guido Adler, Klaus M Debatin, Roland M Schmid
Br J Pharmacol. 2002 Nov; 137(5): 608–620. Published online 2002 Oct 16. doi: 10.1038/sj.bjp.0704870


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Inhibition of nuclear factor kappa B and induction of apoptosis in T-lymphocytes by sulfasalazine

Susanne Liptay, Max Bachem, Georg Häcker, Guido Adler, Klaus M Debatin, Roland M Schmid
Br J Pharmacol. 1999 Dec; 128(7): 1361–1369. doi: 10.1038/sj.bjp.0702937


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Sulfasalazine impacts on ferroptotic cell death and alleviates the tumor microenvironment and glioma-induced brain edema

Tina Sehm, Zheng Fan, Ali Ghoochani, Manfred Rauh, Tobias Engelhorn, Georgia Minakaki, Arnd Dörfler, Jochen Klucken, Michael Buchfelder, Ilker Y. Eyüpoglu, Nicolai Savaskan
Oncotarget. 2016 Jun 14; 7(24): 36021–36033. Published online 2016 Apr 8. doi: 10.18632/oncotarget.8651


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Quantification and Metabolite Identification of Sulfasalazine in Mouse Brain and Plasma Using Quadrupole-Time-of-Flight Mass Spectrometry

Jangmi Choi, Min-Ho Park, Seok-Ho Shin, Jin-Ju Byeon, Byeong ill Lee, Yuri Park, Young G. Shin
Molecules. 2021 Feb; 26(4): 1179. Published online 2021 Feb 22. doi: 10.3390/molecules26041179


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