References from scientific journals

Sulfasalazine: a review of its use in the management of rheumatoid arthritis.

Plosker GL, Croom KF. Plosker GL, et al. Drugs. 2005;65(13):1825-49. doi: 10.2165/00003495-200565130-00008. Drugs. 2005. PMID: 16114981 Review.

Sulfasalazine was associated with broadly similar efficacy to that of various other DMARDs in several randomised, double-blind, comparative trials. ...Sulfasalazine has a relatively short lag time until its onset of action and is often considered to be among the mor …
Sulfasalazine was associated with broadly similar efficacy to that of various other DMARDs in several randomised, double-blind, compa …

Sulfasalazine and related new drugs.

Peppercorn MA. Peppercorn MA. J Clin Pharmacol. 1987 Apr;27(4):260-6. doi: 10.1002/j.1552-4604.1987.tb03009.x. J Clin Pharmacol. 1987. PMID: 2890667 Review. No abstract available.


The association between NAT2 acetylator status and adverse drug reactions of sulfasalazine: a systematic review and meta-analysis.

Yee J, Kim SM, Han JM, Lee N, Yoon HY, Gwak HS. Yee J, et al. Sci Rep. 2020 Feb 27;10(1):3658. doi: 10.1038/s41598-020-60467-8. Sci Rep. 2020. PMID: 32107440 Free PMC article.

Such acetylator status may influence the occurrence of adverse drug reactions (ADRs) during sulfasalazine treatment. This systematic review and meta-analysis aimed to evaluate the association between NAT2 acetylator status and ADRs of sulfasalazine. ...In conclusion …
Such acetylator status may influence the occurrence of adverse drug reactions (ADRs) during sulfasalazine treatment. This systematic …

Year 1977: The active component of sulphasalazine is 5-aminosalycilic acid.

Gomollón F, Marín-Jiménez I. Gomollón F, et al. Gastroenterol Hepatol. 2020 Aug-Sep;43(7):369-370. doi: 10.1016/j.gastrohep.2020.02.003. Gastroenterol Hepatol. 2020. PMID: 32713495 Free article. English, Spanish. No abstract available.


Evolution of olsalazine.

Truelove SC. Truelove SC. Scand J Gastroenterol Suppl. 1988;148:3-6. doi: 10.3109/00365528809101538. Scand J Gastroenterol Suppl. 1988. PMID: 2906475 Review.

Sulphasalazine was first produced nearly 50 years ago through the inspiration of a Swedish doctor, Dr Nanna Svartz. ...Olsalazine was developed to retain the property of sulphasalazine of reaching the colon intact, but also to liberate two molecules of 5-ASA with no …
Sulphasalazine was first produced nearly 50 years ago through the inspiration of a Swedish doctor, Dr Nanna Svartz. ...Olsalazine was …

[Sulfasalazine in rheumatology].

Nurchis P, Garau P, Pala MR, Uras L, Saviano M, Mathieu A. Nurchis P, et al. Ann Ital Med Int. 1990 Jul-Sep;5(3 Pt 1):186-91. Ann Ital Med Int. 1990. PMID: 1981136 Review. Italian.

Sulphasalazine (SLZ) has proved to be a drug effective in inducing clinical improvement or remission in chronic inflammatory rheumatic diseases (other than inflammatory bowel diseases) such as rheumatoid arthritis (RA) and some seronegative spondyloarthropathies, in a fash …
Sulphasalazine (SLZ) has proved to be a drug effective in inducing clinical improvement or remission in chronic inflammatory rheumati …

Sulphasalazine in ulcerative colitis.

[No authors listed] [No authors listed] Drug Ther Bull. 1967 Nov 24;5(24):93-4. Drug Ther Bull. 1967. PMID: 4384228 Review. No abstract available.


Sulphasalazine and lung toxicity.

Parry SD, Barbatzas C, Peel ET, Barton JR. Parry SD, et al. Eur Respir J. 2002 Apr;19(4):756-64. doi: 10.1183/09031936.02.00267402. Eur Respir J. 2002. PMID: 11999006 Free article. Review.

Numerous case reports have been published implicating sulphasalazine in pulmonary toxicity. The authors searched the literature for cases of sulphasalazine induced lung toxicity and the 50 cases identified are discussed here. All published case reports/letters refer …
Numerous case reports have been published implicating sulphasalazine in pulmonary toxicity. The authors searched the literature for c …

Clinical pharmacokinetics of sulphasalazine.

Das KM, Dubin R. Das KM, et al. Clin Pharmacokinet. 1976 Nov-Dec;1(6):406-25. doi: 10.2165/00003088-197601060-00002. Clin Pharmacokinet. 1976. PMID: 15752 Review.

Sulphasalazine consists of 5-aminosalicylic acid and sulphapyridine both linked together by an azo bond. Sulphasalazine is clearly useful in long-term management of ulcerative colitis and may be useful in Crohn's disease. ...
Sulphasalazine consists of 5-aminosalicylic acid and sulphapyridine both linked together by an azo bond. Sulphasalazine is cle …

Pharmacokinetic patterns of sulfasalazine.

Eastwood MA. Eastwood MA. Ther Drug Monit. 1980;2(2):149-52. doi: 10.1097/00007691-198004000-00008. Ther Drug Monit. 1980. PMID: 6132472 Review. No abstract available.