Clinical Trials

A Study to Evaluate Androderm's Effect on Blood Pressure in Adult Hypogonodal Male Participants.

Condition:   Hypogonadism
Intervention:   Drug: Androderm®
Sponsor:   Allergan
Completed

Wed, 25 Mar 2020 12:00:00 EDT

Ambulatory Blood Pressure Monitoring in Oral Testosterone Undecanoate (TU, LPCN 1021) Treated Hypogonadal Men

Condition:   Hypogonadism, Male
Intervention:   Drug: LPCN 1021
Sponsor:   Lipocine Inc.
Completed

Fri, 08 Mar 2019 12:00:00 EST

Testosterone Undecanoate and Quality of Life of Men and Spouses

Condition:   Hypogonadism
Intervention:   Drug: testosterone undecanoate
Sponsor:   Meir Medical Center
Unknown status

Mon, 31 Dec 2012 12:00:00 EST

Phlebotomy Study of Testosterone Undecanoate

Condition:   Hypogonadism
Intervention:   Drug: Oral Testosterone Undecanoate
Sponsor:   Clarus Therapeutics, Inc.
Completed

Mon, 01 Feb 2016 12:00:00 EST

A Comparison of Side Effects in Hypogonadal Men Treated With Natesto Versus Testosterone Injections

Condition:   Hypogonadism, Male
Interventions:   Drug: Testosterone Cypionate 200 MG/ML;   Drug: Intranasal Testosterone
Sponsors:   University of Miami;   Acerus Pharmaceuticals Corporation
Recruiting

Fri, 19 Jun 2020 12:00:00 EDT

Safety of Subcutaneous Testosterone Enanthate in Adult Male Hypogonadism

Condition:   Hypogonadism
Intervention:   Combination Product: Testosterone enanthate auto-injector
Sponsor:   Antares Pharma Inc.
Completed

Thu, 19 May 2016 12:00:00 EDT

A Study of Oral Testosterone Undecanoate (TU) in Hypogonadal Men

Condition:   Hypogonadism
Interventions:   Drug: Oral Testosterone Undecanoate;   Drug: Axiron Testosterone Topical Solution
Sponsors:   Clarus Therapeutics, Inc.;   Syneos Health
Completed

Tue, 29 Mar 2016 12:00:00 EDT

Open-Label Study, Evaluating Patient Satisfaction and Symptom Improvement When Treating Male Hypogonadism With Natesto™

Condition:   Hypogonadism
Intervention:   Drug: NATESTO Testosterone Nasal Gel
Sponsor:   Acerus Pharmaceuticals Corporation
Completed

Wed, 19 Oct 2016 12:00:00 EDT

Effectiveness of Testosterone Undecanoate to Improve Sexual Function in Postmenopausal Women

Condition:   Female Sexual Dysfunction
Interventions:   Drug: Testosterone undecanoate;   Drug: placebo
Sponsor:   Chulalongkorn University
Completed

Mon, 12 Nov 2012 12:00:00 EST

Effect of Androgel on Type 2 Diabetic Males With Hypogonadism

Condition:   Diabetes Mellitus Type 2
Interventions:   Drug: androgel;   Drug: androgel 10g;   Drug: placebo
Sponsors:   Kaleida Health;   Solvay Pharmaceuticals
Unknown status

Tue, 11 Jul 2006 12:00:00 EDT

Effects of Testosterone Undecanoate vs Placebo on Intrahepatic Fat Content in Obese Men With T2DM and Hypogonadism

Conditions:   Fatty Liver;   Obesity;   Type2 Diabetes Mellitus;   Hypogonadism, Male
Interventions:   Drug: Testosterone Undecanoate;   Drug: Placebo
Sponsors:   Alexandra Kautzky-Willer;   Bayer
Not yet recruiting

Fri, 22 Feb 2019 12:00:00 EST

Dosing Flexibility Study of Oral Testosterone Undecanoate (TU, LPCN 1021)

Condition:   Hypogonadism, Male
Intervention:   Drug: LPCN 1021
Sponsor:   Lipocine Inc.
Completed

Tue, 08 Aug 2017 12:00:00 EDT

Dosing Validation Study of Oral Testosterone Undecanoate (TU, LPCN 1021).

Condition:   Hypogonadism, Male
Intervention:   Drug: LPCN 1021
Sponsor:   Lipocine Inc.
Completed

Tue, 08 Aug 2017 12:00:00 EDT

Open-label, Follow-up Study of Oral Testosterone Undecanoate in Hypogonadal Men

Condition:   Male Hypogonadism
Interventions:   Drug: Oral testosterone undecanoate;   Drug: Transdermal testosterone gel (AndroGel)
Sponsor:   Clarus Therapeutics, Inc.
Completed

Wed, 03 Oct 2012 12:00:00 EDT

Trial of Testosterone Undecanoate for Optimizing Performance During Military Operations

Conditions:   Caloric Restriction;   Exercise;   Sleep
Interventions:   Drug: Testosterone Undecanoate;   Drug: Sesame Oil
Sponsors:   Pennington Biomedical Research Center;   United States Army Research Institute of Environmental Medicine;   United States Department of Defense;   University of Arkansas
Completed

Wed, 09 Oct 2019 12:00:00 EDT

Subcutaneous Testosterone Enanthate Safety in Adult Men Diagnosed With Hypogonadism

Condition:   Hypogonadism
Intervention:   Combination Product: Testosterone enanthate auto-injector
Sponsor:   Antares Pharma Inc.
Completed

Wed, 22 Jul 2015 12:00:00 EDT

Patient Satisfaction After Switching to Oral Testosterone Undecanoate

Condition:   Testosterone Deficiency
Intervention:   Drug: Jatenzo
Sponsors:   University of Miami;   Clarus Therapeutics
Recruiting

Fri, 30 Jul 2021 12:00:00 EDT

Natesto Effects on Testosterone, Luteinizing Hormone, Follicle Stimulating Hormone and Semen Parameters

Condition:   Hypogonadism, Male
Intervention:   Drug: Natesto
Sponsors:   University of Miami;   Acerus Pharmaceuticals Corporation
Completed

Thu, 29 Jun 2017 12:00:00 EDT

ESPRIT Study in Hypogonadal Men

Condition:   Hypogonadism
Intervention:   Drug: AndroGel (testosterone gel) 1%
Sponsors:   Abbott;   Fovea
Completed

Mon, 14 Jun 2010 12:00:00 EDT

Subcutaneous Testosterone Replacement Efficacy and Safety in Adult Men Diagnosed With Hypogonadism

Condition:   Hypogonadism
Intervention:   Combination Product: Testosterone enanthate auto-injector
Sponsor:   Antares Pharma Inc.
Completed

Tue, 10 Jun 2014 12:00:00 EDT

The Effects of Natesto For Treatment Of Hypogonadism

Conditions:   Hypogonadism, Male;   Infertility, Male;   Testosterone Deficiency
Intervention:   Drug: Natesto Nasal Product
Sponsor:   Baylor College of Medicine
Not yet recruiting

Fri, 22 Jan 2021 12:00:00 EST

The Therapy of Nebido as Mono or in Combination With PDE-5 Inhibitors in Hypogonadal Patients With Erectile Dysfunction

Conditions:   Hypogonadism;   Erectile Dysfunction
Intervention:   Drug: Testosterone Undecanoate,1000mg
Sponsors:   Chulalongkorn University;   Ramathibodi Hospital;   Siriraj Hospital
Completed

Fri, 12 Jan 2007 12:00:00 EST

CYP19A1 (Cytochrome P450 Family 19 Subfamily A Member 1) Gene and Pharmacogenetics of Response to Testosterone Therapy

Condition:   Hypogonadism
Intervention:   Drug: Testosterone Cypionate
Sponsors:   VA Office of Research and Development;   Baylor College of Medicine
Completed

Wed, 22 Jun 2011 12:00:00 EDT

Extreme Bipolar Androgen Therapy With Darolutamide and Testosterone Cypionate in Patients With Metastatic Castration-Resistant Prostate Cancer (ExBAT Trial)

Condition:   Prostate Cancer
Interventions:   Drug: Testosterone Cypionate;   Drug: Darolutamide
Sponsors:   Latin American Cooperative Oncology Group;   Bayer
Recruiting

Tue, 22 Sep 2020 12:00:00 EDT

Pharmacokinetic Study of Testosterone Enanthate

Condition:   Hypogonadism
Interventions:   Drug: QuickShot™ - 50 mg Treatment B;   Drug: QuickShot™ - 100 mg Treatment A;   Drug: Delatestryl 200 mg IM Treatment C
Sponsor:   Antares Pharma Inc.
Completed

Wed, 26 Jun 2013 12:00:00 EDT

Pharmacokinetic Study of Subcutaneous Testosterone Enanthate

Condition:   Hypogonadism
Intervention:   Combination Product: Testosterone enanthate auto-injector
Sponsor:   Antares Pharma Inc.
Completed

Mon, 08 Sep 2014 12:00:00 EDT

A Study of Axiron® in Healthy Participants

Condition:   Healthy Volunteers
Intervention:   Drug: Axiron
Sponsor:   Eli Lilly and Company
Completed

Fri, 06 Dec 2013 12:00:00 EST

Testosterone Replacement in Non-alcoholic Steatohepatitis (TEREPINS)

Conditions:   Nonalcoholic Steatohepatitis;   Hypogonadism
Intervention:   Drug: testosterone undecanoate
Sponsors:   Sheffield Teaching Hospitals NHS Foundation Trust;   Bayer
Completed

Fri, 09 Aug 2013 12:00:00 EDT

Testosterone Replacement Therapy in Chronic Spinal Cord Injury

Conditions:   Spinal Cord Injury;   Hypogonadism
Intervention:   Drug: Testosterone Transdermal System (Androderm 5 mg patch)
Sponsors:   VA Office of Research and Development;   Kessler Institute for Rehabilitation
Completed

Mon, 19 Dec 2005 12:00:00 EST

Metabolic Syndrome Criteria and the Effect of Testosterone Treatment in Young Men With Hypogonadism

Condition:   Hypogonadism
Intervention:   Drug: Testosteron
Sponsor:   Gulhane School of Medicine
Completed

Mon, 12 Jul 2010 12:00:00 EDT

Effects of External Testosteron Intake on the Choroid: Enhance-depth Imaging Optical Coherence Tomography Study

Condition:   Effects of the External Testosteron Intake Over the Choroids of the Patients With Androgen Deficiency
Intervention:   Drug: external testosteron
Sponsor:   Neon Hospital
Completed

Fri, 10 Apr 2020 12:00:00 EDT

Safety and Efficacy Trial of Testosterone Undecanoate

Condition:   Male Hypogonadism
Intervention:   Drug: Oral testosterone undecanoate
Sponsors:   Clarus Therapeutics, Inc.;   inVentiv Health Clinical
Completed

Thu, 10 Jan 2013 12:00:00 EST

Safety and Efficacy of Oral LPCN 1021 in Men With Low Testosterone or Hypogonadism

Condition:   Male Hypogonadism
Interventions:   Drug: Oral testosterone undecanoate, LPCN 1021;   Drug: Topical testosterone gel 1.62 %
Sponsors:   Lipocine Inc.;   Syneos Health;   PPD
Completed

Fri, 07 Mar 2014 12:00:00 EST

Nebido Versus Placebo in Elderly Men With Typical Symptoms of Late Onset Hypogonadism Over a Period of 54 Weeks

Condition:   Hypogonadism
Interventions:   Drug: NEBIDO;   Drug: PLACEBO
Sponsor:   Bayer
Withdrawn

Fri, 04 Jul 2008 12:00:00 EDT

The Effect of IM Testosterone Undecanoate on Biochemical and Anthropometric Characteristics of Metabolic Syndrome in Hypogonadal Men

Conditions:   Metabolic Syndrome;   Hypogonadism
Interventions:   Drug: Nebido (testosterone undecanoate);   Drug: Placebo
Sponsor:   Russian Academy of Medical Sciences
Unknown status

Fri, 13 Jun 2008 12:00:00 EDT

Testosterone Effects on Pelvic Floor Muscles

Conditions:   Urinary Incontinence;   Menopause
Interventions:   Drug: Testosterone Enanthate;   Drug: Placebo
Sponsor:   Brigham and Women's Hospital
Unknown status

Fri, 19 Jul 2019 12:00:00 EDT

Study to Compare DITEST to Testosterone Undecanoate in Adult Men With Hypogonadism

Condition:   Male Hypogonadism
Interventions:   Drug: DITEST;   Drug: Testosterone undecanoate
Sponsors:   Diurnal Limited;   Sheffield Teaching Hospitals NHS Foundation Trust;   Simbec Research;   Voet Consulting;   EMAS Pharma;   Medical Matters International Ltd.;   Brush Clinical Research Ltd.;   Manchester University NHS Foundation Trust;   Covance
Completed

Thu, 17 Nov 2016 12:00:00 EST

Effects of Testosterone Plus Dutasteride or Placebo on Muscle Strength, Body Composition and Metabolism in Transmen

Conditions:   Transgenderism;   Hypogonadism
Interventions:   Drug: dutasteride 5 mg/day;   Drug: Testosterone Undecanoate
Sponsor:   Unita Complessa di Ostetricia e Ginecologia
Completed

Fri, 11 Sep 2020 12:00:00 EDT

Effect of Androgel on Atherogenesis in Type 2 Diabetic Males With Hypogonadotrophic Hypogonadism

Condition:   Type 2 Diabetic Male With Hypogonadotrophic Hypogonadism
Interventions:   Drug: androgel;   Drug: placebo
Sponsors:   University at Buffalo;   Solvay Pharmaceuticals
Unknown status

Tue, 01 May 2007 12:00:00 EDT

Long-term Safety Study of Intramuscular Injections of 750 mg and 1000 mg Testosterone Undecanoate in Hypogonadal Men

Conditions:   Hypogonadism;   Primary Hypogonadism;   Secondary Hypogonadism
Interventions:   Drug: Testosterone Undecanoate 750 mg;   Drug: Testosterone Undecanoate 1000 mg
Sponsor:   Endo Pharmaceuticals
Completed

Tue, 01 May 2007 12:00:00 EDT

A Study to Monitor Ambulatory Blood Pressure Monitoring in Hypogonadal Men Treated With Nasal Testosterone Gel

Condition:   Hypogonadism
Intervention:   Drug: Natesto
Sponsor:   Acerus Pharmaceuticals Corporation
Recruiting

Mon, 26 Jul 2021 12:00:00 EDT

Pharmacokinetic Study to Determine Time to Steady-state

Conditions:   Male Hypogonadism;   Primary Hypogonadism;   Secondary Hypogonadism
Intervention:   Drug: Testosterone undecanoate
Sponsor:   Clarus Therapeutics, Inc.
Completed

Tue, 02 Jun 2009 12:00:00 EDT

Vogelxo(R) ABPM Study in Hypogandal Men

Condition:   Hypogonadism, Male
Intervention:   Drug: Vogelxo
Sponsor:   Upsher-Smith Laboratories
Recruiting

Tue, 22 Sep 2020 12:00:00 EDT

Testosterone for Penile Rehabilitation After Radical Prostatectomy

Conditions:   Hypogonadism;   Erectile Dysfunction
Interventions:   Drug: Testim®;   Other: Placebo Testim®;   Drug: Viagra®
Sponsor:   Mohit Khera
Terminated

Fri, 20 Feb 2009 12:00:00 EST

The Effect of Various Amounts of Fat on PK of Oral Testosterone Undecanoate

Condition:   Hypogonadism
Intervention:   Drug: Oral Testosterone Undecanoate
Sponsors:   Clarus Therapeutics, Inc.;   Celerion
Completed

Mon, 03 Oct 2016 12:00:00 EDT

Locomotor Training With Testosterone to Promote Bone and Muscle Health After Spinal Cord Injury

Conditions:   Spinal Cord Injury;   Spinal Cord Injuries;   Trauma, Nervous System;   Wounds and Injury;   Central Nervous System Diseases;   Spinal Cord Diseases;   Gonadal Disorders;   Endocrine System Diseases;   Hypogonadism;   Genital Diseases, Male;   Spinal Cord Trauma;   Injuries, Spinal Cord;   Walking, Difficulty;   Gait Disorders, Neurologic;   Locomotion Disorder, Neurologic;   Wounds and Injuries;   Nervous System Diseases;   Testosterone Deficiency;   Androgen Deficiency;   Hormone Deficiency
Interventions:   Drug: Testosterone Enanthate;   Behavioral: Locomotor Training
Sponsors:   North Florida Foundation for Research and Education;   North Florida/South Georgia Veterans Health System;   Brooks Rehabilitation;   University of Florida
Recruiting

Wed, 08 Jul 2020 12:00:00 EDT

Odense Androgen Study - The Effect of Testim and Training in Hypogonadal Men

Conditions:   Hypogonadism;   Metabolic Syndrome
Interventions:   Drug: Testim;   Behavioral: Strength training;   Drug: placebo
Sponsor:   Odense University Hospital
Unknown status

Wed, 18 Jun 2008 12:00:00 EDT

Testosterone Plus Finasteride Treatment After Spinal Cord Injury

Conditions:   Spinal Cord Injury;   Spinal Cord Injuries;   Trauma, Nervous System;   Wounds and Injuries;   Central Nervous System Diseases;   Nervous System Diseases;   Spinal Cord Diseases;   Gonadal Disorders;   Endocrine System Diseases;   Hypogonadism;   Genital Diseases, Male
Interventions:   Drug: testosterone enanthate, finasteride;   Drug: placebo
Sponsors:   VA Office of Research and Development;   University of Florida
Recruiting

Thu, 25 Sep 2014 12:00:00 EDT

Efficacy and Safety of Oral Testosterone Undecanoate in Hypogonadal Men

Condition:   Hypogonadism, Male
Interventions:   Drug: SOV2012-F1;   Drug: AndroGel
Sponsors:   Marius Pharmaceuticals;   Syneos Health
Completed

Mon, 26 Jun 2017 12:00:00 EDT

Testopel ® vs. Generic Testosterone Pellets.

Condition:   Hypogonadism
Interventions:   Drug: Testopel;   Drug: Testosterone Pellet, 100Mg;   Drug: Testosterone Pellet, 200 Mg
Sponsors:   University of Miami;   Empower Pharmacy
Recruiting

Fri, 21 Aug 2020 12:00:00 EDT

Assessment of Long Term Treatment With Testosterone Undecanoate in Males With Hypogonadism

Condition:   Hypogonadism
Intervention:   Drug: Testosterone undecanoate (TU) - NebidoTM
Sponsor:   Bayer
Completed

Thu, 22 Sep 2005 12:00:00 EDT

Testosterone Revival Abolishes Negative Symptoms, Fosters Objective Response and Modulates Enzalutamide Resistance

Condition:   Castration Resistant Metastatic Prostate Cancer
Interventions:   Drug: Testosterone cypionate;   Drug: Enzalutamide;   Drug: Testosterone Enanthate
Sponsors:   Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins;   United States Department of Defense
Completed

Mon, 10 Nov 2014 12:00:00 EST

Endothelial Dysfunction, Inflammation and Insulin Resistance in Congenital Hypogonadism and Effect of Testosteron Replacement Therapy

Condition:   Hypogonadotrophic Hypogonadism
Interventions:   Drug: Testosterone 250mg injection;   Drug: Testosteron 50 mg transdermal gel
Sponsor:   Gulhane School of Medicine
Completed

Tue, 24 Jun 2014 12:00:00 EDT

Safety and Efficacy Trial of Oral Testosterone Undecanoate (TU) in Hypogonadal Men

Condition:   Male Hypogonadism
Interventions:   Drug: Oral testosterone undecanoate;   Drug: topical testosterone gel
Sponsors:   Clarus Therapeutics, Inc.;   PharmaNet;   Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Completed

Wed, 27 Jul 2011 12:00:00 EDT

A Randomized Study of Testosterone Replacement in Patients With Low Risk Hormone Refractory Prostate Cancer

Condition:   Prostate Cancer
Interventions:   Drug: Androderm® 2.5mg;   Drug: Androderm® 5.0mg;   Drug: Androderm® 7.5mg
Sponsor:   University of Chicago
Completed

Tue, 24 Aug 2010 12:00:00 EDT

A Pharmacokinetic (PK) Study to Compare the Absorption of Two Formulations of Transdermal Testosterone Spray and Intrinsa®

Condition:   Hypoactive Sexual Desire Disorder
Interventions:   Drug: Testosterone Spray 5% and 1%;   Drug: Intrinsa® Patch and Testosterone Spray 5%;   Drug: Intrinsa® Patch and Testosterone Spray 1%
Sponsor:   VIVUS, Inc.
Terminated

Wed, 31 Mar 2010 12:00:00 EDT

AndroGel in Men With Major Depression and Incomplete Response to Antidepressant Treatment

Condition:   Depressive Disorder, Major
Interventions:   Drug: Testosterone gel;   Drug: Placebo
Sponsors:   Mclean Hospital;   Solvay Pharmaceuticals
Completed

Mon, 20 Mar 2006 12:00:00 EST

Use of Nebido® to Assess Tolerability and Treatment Outcomes in Daily Clinical Practice

Conditions:   Male;   Hypogonadism
Intervention:   Drug: Testosterone Undecanoate (Nebido, BAY86-5037)
Sponsor:   Bayer
Completed

Tue, 12 Dec 2006 12:00:00 EST

Androgen Regulation of Priapism in Sickle Cell Disease

Conditions:   Priapism;   Sickle Cell Disease;   Hypogonadism
Intervention:   Drug: Transdermal Androgel
Sponsor:   Johns Hopkins University
Withdrawn

Thu, 12 Sep 2013 12:00:00 EDT

Bipolar Androgen Therapy +/- Carboplatin in mCRPC With/Without Homologous Recombination Deficiency

Conditions:   Castration-resistant Prostate Cancer;   Homologous Recombination Deficiency
Interventions:   Drug: Testosterone Enanthate 100 MG/ML Injectable Solution;   Drug: Testosterone Enanthate 100 MG/ML Injectable Solution / Carboplatin AUC 5
Sponsor:   St Vincent's Hospital, Sydney
Recruiting

Fri, 11 May 2018 12:00:00 EDT

Study to Determine the Effect of Food on the Absorption of an Oral Testosterone Undecanoate Formulation

Condition:   Male Hypogonadism
Intervention:   Drug: Oral testosterone undecanoate (containing 300 mg T)
Sponsor:   Clarus Therapeutics, Inc.
Completed

Fri, 19 Jun 2009 12:00:00 EDT

Androgen for Leydig Cell Proliferation

Conditions:   Klinefelter Syndrome;   Hypergonadotropic Hypogonadism;   Hypergonadotropic Azospermia;   Hypergonadotropic Cryptozoospermia
Interventions:   Drug: Testosterone undecanoate;   Drug: Castor Oil
Sponsor:   University of Roma La Sapienza
Completed

Tue, 21 Sep 2010 12:00:00 EDT

A Study of the Effect of Topical Testosterone Replacement Therapy on Blood Pressure in Adult Male Participants With Hypogonadism

Condition:   Hypogonadism
Intervention:   Drug: AndroGel 1.62%
Sponsor:   AbbVie
Active, not recruiting

Tue, 18 Feb 2020 12:00:00 EST

Short-term Testosterone Replacement in Testicular Cancer Survivors

Condition:   Testicular Cancer
Interventions:   Drug: Androgel (Testosterone gel);   Drug: Placebo gel
Sponsor:   University Medical Center Groningen
Recruiting

Mon, 13 Nov 2017 12:00:00 EST

Oral Testosterone for Fatigue in Male Multiple Sclerosis Patients

Conditions:   Multiple Sclerosis;   Fatigue
Interventions:   Drug: Testosterone undecanoate;   Drug: placebo
Sponsors:   Health Sciences Centre, Winnipeg, Manitoba;   University of Manitoba;   Consortium of Multiple Sclerosis Centers;   Manitoba Medical Service Foundation
Terminated

Wed, 25 Jan 2012 12:00:00 EST

A Study to Test a Measure of Symptoms of Older Men With Low Testosterone On and Off Testosterone Replacement Treatment (P05815)

Condition:   Hypogonadism
Interventions:   Drug: Testim 1% (testosterone gel);   Drug: Placebo
Sponsor:   Merck Sharp & Dohme Corp.
Terminated

Wed, 16 Nov 2005 12:00:00 EST

Study on Effects of Testosterone Replacement Therapy in Hypogonadal Type 2 Diabetic Patients" (SETH2)

Conditions:   Hypogonadism, Male;   Diabetes Mellitus, Type 2;   Obesity
Interventions:   Drug: Testosterone Undecanoate;   Drug: Placebo
Sponsor:   University Medical Centre Ljubljana
Completed

Thu, 03 Jan 2019 12:00:00 EST

Hormones and Decision Making

Condition:   Dyssocial Behavior
Interventions:   Drug: testosterone propionate;   Drug: 0.5% cholorbutanol, saline
Sponsor:   University of Texas at Austin
Completed

Thu, 29 Apr 2021 12:00:00 EDT

Efficacy of Nebido on Bone Mineral Density (BMD) in Hypogonadal Paraplegic Patients With Confirmed Osteoporosis

Conditions:   Hypogonadism;   Paraplegia;   Bone Density;   Osteoporosis
Intervention:   Drug: Testosterone Undeconate (Nebido-R, BAY86-5037)
Sponsor:   Bayer
Completed

Fri, 06 Feb 2009 12:00:00 EST

Advanced Virtual Exercise Environment Device for Use by Persons With Physical Disabilities

Condition:   Physically Disabled
Interventions:   Other: AVEED: Arm rotation, video display;   Other: AVEED: Arm rotation, without video display;   Other: AVEED: Leg rotation, arm-energy input, video display;   Other: AVEED: Leg rotation, arm-energy input, without video display
Sponsors:   University of Alabama at Birmingham;   National Institute on Disability, Independent Living, and Rehabilitation Research
Completed

Tue, 13 Dec 2016 12:00:00 EST

Efficacy and Tolerability of Testogel/Nebido in Combination With Exercise and Diet in Hypogonadal Male Patients

Condition:   Hypogonadism
Intervention:   Drug: Testosterone Undeconate (Nebido-R, BAY86-5037)
Sponsor:   Bayer
Completed

Thu, 19 Feb 2009 12:00:00 EST

NEBIDO in Symptomatic Late Onset Hypogonadism (SLOH)

Condition:   Hypogonadism
Interventions:   Drug: Testosterone Undeconate (Nebido, BAY86-5037);   Drug: Placebo
Sponsor:   Bayer
Terminated

Thu, 25 Mar 2010 12:00:00 EDT

Improving Quality of Life of Prostate Cancer Survivors With Androgen Deficiency

Condition:   Prostate Cancer
Interventions:   Drug: Testosterone Cypionate 100 MG/ML;   Drug: Placebo
Sponsors:   Dana-Farber Cancer Institute;   National Institute on Aging (NIA)
Recruiting

Tue, 23 Oct 2018 12:00:00 EDT

Sequential Testosterone and Enzalutamide Prevents Unfavorable Progression

Condition:   Castration Resistant Metastatic Prostate Cancer
Interventions:   Drug: Testosterone cypionate;   Drug: Enzalutamide;   Drug: Testosterone enanthate
Sponsors:   Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins;   United States Department of Defense
Recruiting

Mon, 27 Apr 2020 12:00:00 EDT

Testosterone and Myocardial Perfusion in Coronary Heart Disease (CHD)

Condition:   Coronary Heart Disease
Intervention:   Drug: Testosterone undecanoate
Sponsors:   Imperial College London;   Organon
Completed

Mon, 17 Oct 2005 12:00:00 EDT

Effect of Testosterone Therapy in Men With Alzheimer's Disease and Low Testosterone

Conditions:   Alzheimer's Disease;   Hypogonadism
Intervention:   Drug: AndroGel (Solvay Pharmaceuticals)
Sponsors:   VA Medical Center, Houston;   Solvay Pharmaceuticals
Completed

Thu, 26 Oct 2006 12:00:00 EDT

The Effect of Testosteron Replacement Treatment on the Fibroblast Growth Factor-23, Asymmetric Dimethylarginine and Vitamin D Levels in the Congenital Hypogonadotropic Hypogonadism

Condition:   Hypogonadism
Intervention:   Drug: Testosterone
Sponsor:   Gulhane School of Medicine
Completed

Fri, 11 Apr 2014 12:00:00 EDT

Biomarker Analysis of Castration-resistant Prostate Cancer Undergoing Bipolar Androgen Therapy

Condition:   Prostate Cancer
Intervention:   Drug: Testosterone cypionate
Sponsors:   Hospital Sirio-Libanes;   Hospital Moinhos de Vento
Recruiting

Thu, 11 Jun 2020 12:00:00 EDT

Bioequivalence Study of Test and Reference Testosterone Topical Gel, 1.62% Metered Pump in Testosterone Deficient Adult Male Subjects Under Fasting Conditions

Conditions:   Primary Hypogonadism;   Hypogonadotropic Hypogonadism
Interventions:   Drug: Testosterone Topical Gel, 1.62% Metered Pump;   Drug: AndroGel (testosterone gel) 1.62% Metered-Dose Pump
Sponsors:   Amneal Pharmaceuticals, LLC;   Phase One Solutions, Inc.
Completed

Thu, 10 Apr 2014 12:00:00 EDT

Testosterone Patch's Effects on the Cardiovascular System and Libido

Condition:   Hypoactive Sexual Desire Disorder
Intervention:   Drug: Intrinsa Transdermal testosterone patch
Sponsors:   Imperial College Healthcare NHS Trust;   Royal Brompton & Harefield NHS Foundation Trust;   Chelsea and Westminster NHS Foundation Trust
Completed

Thu, 23 Sep 2010 12:00:00 EDT

Testosterone in Bariatric Patients

Conditions:   Bariatric Surgery Candidate;   Male Hypogonadism;   Muscle Loss
Intervention:   Drug: Testosterone Undecanoate
Sponsor:   Hospital of South West Denmark
Recruiting

Fri, 26 Oct 2018 12:00:00 EDT

Efficacy and Safety of Androgel in the Treatment of Hypogonadal and Low Testosterone Men With Type 2 Diabetes

Conditions:   Type 2 Diabetes;   Hypogonadism
Intervention:   Drug: Androgel (testosterone gel)
Sponsor:   Solvay Pharmaceuticals
Completed

Thu, 01 Sep 2005 12:00:00 EDT

Cycled Testosterone Administration During Pulmonary Rehabilitation in Early Stage COPD

Condition:   COPD
Interventions:   Drug: Testosterone Enanthate;   Drug: Placebo
Sponsor:   The University of Texas Medical Branch, Galveston
Not yet recruiting

Mon, 17 Sep 2018 12:00:00 EDT

Xiaflex® Plus Testosterone Treatment Pilot Study Protocol

Condition:   Peyronie's Disease (PD)
Interventions:   Drug: Xiaflex®;   Drug: Aveed
Sponsor:   Men's Health Boston
Completed

Thu, 24 Jan 2019 12:00:00 EST

Benefit of the Treatment With Testosterone in Chronic Heart Failure Testosterone Deficiency Subjects

Condition:   Heart Failure
Interventions:   Drug: Testosterone undecanoate;   Drug: Saline isotonic solution
Sponsors:   Fundacion para la Formacion e Investigacion Sanitarias de la Region de Murcia;   Hospital Universitario Virgen de la Arrixaca;   Germans Trias i Pujol Hospital
Completed

Mon, 18 Mar 2013 12:00:00 EDT

A Study of Megestrol Acetate Alone or in Combination With Testosterone Enanthate Drug in the Treatment of HIV-Associated Weight Loss

Conditions:   HIV Infections;   HIV Wasting Syndrome
Interventions:   Drug: Testosterone enanthate;   Drug: Megestrol acetate
Sponsor:   National Institute of Allergy and Infectious Diseases (NIAID)
Completed

Fri, 31 Aug 2001 12:00:00 EDT

Efficacy and Safety of Testosterone Nasal Gel for Treating Hypogonadism in Men.

Condition:   Hypogonadism
Interventions:   Drug: Nasotestt 5 mg;   Drug: Androgel 50 mg;   Other: Nasotestt Placebo;   Other: Androgel Placebo
Sponsors:   FBM Industria Brasileira Ltda;   Azidus Brasil Scientific Research and Development Ltda
Unknown status

Wed, 13 Sep 2017 12:00:00 EDT

Testosterone Treatment for Multiple Sclerosis

Condition:   Multiple Sclerosis
Intervention:   Drug: Androgel 10 grams of gel containing 100 mg of testosterone
Sponsors:   University of California, Los Angeles;   National Multiple Sclerosis Society
Completed

Thu, 30 Nov 2006 12:00:00 EST

Study of Testosterone and rHGH in FSHD

Condition:   Facioscapulohumeral Muscular Dystrophy
Interventions:   Drug: Testosterone Enanthate;   Drug: Somatropin
Sponsor:   University of Rochester
Active, not recruiting

Fri, 21 Apr 2017 12:00:00 EDT

Safety and Efficacy of LibiGel® for Treatment of Hypoactive Sexual Desire Disorder in Surgically Menopausal Women

Condition:   Hypoactive Sexual Desire Disorder
Interventions:   Drug: testosterone gel;   Drug: placebo gel
Sponsor:   BioSante Pharmaceuticals
Completed

Mon, 14 Apr 2008 12:00:00 EDT

Safety and Efficacy of LibiGel® for Treatment of Hypoactive Sexual Desire Disorder in Postmenopausal Women

Condition:   Hypoactive Sexual Desire Disorder
Interventions:   Drug: testosterone gel;   Drug: placebo gel
Sponsor:   BioSante Pharmaceuticals
Completed

Tue, 12 Feb 2008 12:00:00 EST

Safety and Efficacy of LibiGel® for the Treatment of Hypoactive Sexual Desire Disorder in Surgically Menopausal Women

Condition:   Hypoactive Sexual Desire Disorder
Interventions:   Drug: testosterone gel;   Drug: placebo gel
Sponsor:   BioSante Pharmaceuticals
Completed

Tue, 12 Feb 2008 12:00:00 EST

Assessment of Blood From Men Receiving Oral TU in Various Collection Tubes

Condition:   Hypogonadism, Male
Intervention:   Drug: Testosterone Undecanoate
Sponsors:   Clarus Therapeutics, Inc.;   Celerion; Syneos Health; ARUP Laboratories
Completed

Tue, 04 Jun 2019 12:00:00 EDT

Hormonal Contraception in Healthy Young Men (P42306)(COMPLETED)(P06057)

Condition:   Contraception
Interventions:   Drug: etonogestrel with testosterone undecanoate;   Drug: Placebo
Sponsors:   Merck Sharp & Dohme Corp.;   Bayer
Completed

Mon, 27 Nov 2006 12:00:00 EST

Visceral Adiposity Index and Triglyceride/High-density Lipoprotein Cholesterol Ratio in the Congenital Hypogonadotropic Hypogonadism and Effect of Testosteron Treatment

Condition:   Hypogonadism
Intervention:   Drug: Testosterone
Sponsor:   Gulhane School of Medicine
Completed

Fri, 11 Apr 2014 12:00:00 EDT

Pilot Pharmacokinetic Study of Oral Testosterone Ester Formulations in Hypogonadal Men

Condition:   Hypogonadism
Interventions:   Drug: Testosterone undecanoate;   Drug: Testosterone enanthate
Sponsors:   Clarus Therapeutics, Inc.;   Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Completed

Thu, 03 Mar 2016 12:00:00 EST

Optimizing Protein Intake in Older Americans With Mobility Limitations

Condition:   Mobility Limitation
Intervention:   Drug: Testosterone enanthate
Sponsors:   Brigham and Women's Hospital;   National Institute on Aging (NIA)
Completed

Wed, 12 Jan 2011 12:00:00 EST

Influence of Administration Route of Testosterone on Male Fertility

Condition:   Hypogonadism
Interventions:   Drug: MPP10, testosterone;   Drug: Testosterone
Sponsor:   Acerus Pharmaceuticals Corporation
Withdrawn

Thu, 26 Jun 2008 12:00:00 EDT

Extension Study to Assess Persistence of Benefit of LibiGel for the Treatment of Hypoactive Sexual Desire Disorder (HSDD)

Condition:   Hypoactive Sexual Desire Disorder
Interventions:   Drug: transdermal testosterone gel 1%;   Drug: placebo gel
Sponsor:   BioSante Pharmaceuticals
Completed

Sun, 07 Nov 2010 12:00:00 EDT

Body Composition in Infants With Klinefelter Syndrome and Effects of Testosterone Treatment

Condition:   Klinefelter Syndrome
Intervention:   Drug: testosterone cypionate 200mg/ml
Sponsor:   University of Colorado, Denver
Completed

Fri, 03 Apr 2015 12:00:00 EDT

A Phase 1/2a Study to Determine the Dose Response Pharmacokinetics of TSX-011 (Testosterone Undecanoate) in Hypogonadal Males

Conditions:   Hypogonadism;   Hypogonadism, Male;   Gonadal Disorders;   Endocrine System Diseases;   Testosterone Deficiency
Intervention:   Drug: TSX-011
Sponsor:   TesoRx Pharma, LLC
Terminated

Tue, 07 Nov 2017 12:00:00 EST

The Effect of Testosterone Replacement on the High Density Lipoprotein Cholesterol Subgroups

Condition:   Secondary Hypogonadism
Interventions:   Drug: Testosteron 250mg injection;   Drug: Testosterone 50mg transdermal application
Sponsor:   Gulhane School of Medicine
Completed

Tue, 18 Oct 2011 12:00:00 EDT

The Cardiac Benefit of Testosterone Replacement in Men With Low Testosterone Levels With Coronary Artery Disease After Successful Intervention of the Blockage or Narrowed Heart Artery

Condition:   Coronary Artery Disease
Interventions:   Drug: AndroGel 5 Grams;   Drug: Placebo
Sponsors:   Icahn School of Medicine at Mount Sinai;   Abbott
Completed

Tue, 19 Dec 2006 12:00:00 EST

Effects of Andriol Testocaps in Symptomatic Late-Onset Hypogonadism (43203)

Conditions:   Hypogonadism;   Androgens
Interventions:   Drug: Oral testosterone undecanoate (Andriol);   Drug: Placebo
Sponsor:   Merck Sharp & Dohme Corp.
Completed

Tue, 13 Feb 2007 12:00:00 EST

Testosterone in Metastatic Renal Cell Carcinoma Patients

Condition:   Metastatic Renal Cell Carcinoma
Intervention:   Drug: Testosterone undecanoate and sunitinib or pazopanib
Sponsor:   Kidney Cancer Research Bureau
Completed

Wed, 20 Dec 2017 12:00:00 EST

Role of Anabolic Steroids on Intensive Care Unit-Acquired Weakness

Condition:   Critical Illness Polyneuropathies
Interventions:   Drug: Testosterone cypionate;   Other: Standard nutrition and physical therapy at ICU
Sponsor:   Hospital de Clinicas de Porto Alegre
Unknown status

Wed, 01 Feb 2017 12:00:00 EST

Oral Androgens in Man-4: (Short Title: Oral T-4)

Condition:   Contraception
Interventions:   Drug: Testosterone Enanthate;   Drug: Dutasteride;   Other: placebo sesame oil
Sponsors:   University of Washington;   GlaxoSmithKline
Completed

Tue, 14 Nov 2006 12:00:00 EST

RE-sensitizing With Supraphysiologic Testosterone to Overcome REsistance (The RESTORE Study)

Condition:   Prostate Cancer
Interventions:   Drug: Testosterone cypionate;   Drug: Testosterone Enanthate;   Drug: Abiraterone acetate (Cohort B = CLOSED TO ACCRUAL);   Drug: Enzalutamide (Cohort A = CLOSED TO ACCRUAL)
Sponsors:   Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins;   National Cancer Institute (NCI)
Recruiting

Tue, 18 Mar 2014 12:00:00 EDT

Study to Determine the Effects of Testosterone Replacement Therapy in Aging Men With Androgen Deficiency

Condition:   Men With Low Testosterone Levels
Interventions:   Drug: Testosterone Enanthate;   Other: Placebo
Sponsors:   Leonard S. Marks, M.D.;   Solvay Pharmaceuticals;   Watson Pharmaceuticals
Completed

Mon, 12 Sep 2005 12:00:00 EDT

The Effect of Testosterone Replacement on Bone Mineral Density in Boys and Men With Anorexia Nervosa

Condition:   Bone Metabolism
Intervention:   Drug: testosterone cypionate
Sponsor:   Massachusetts General Hospital
Withdrawn

Mon, 02 Mar 2009 12:00:00 EST

A Bioequivalence Study of Testosterone Cypionate in Hypogonadal Males

Condition:   Hypogonadism
Interventions:   Biological: Test formulation;   Biological: Reference formulation
Sponsor:   Pfizer
Completed

Thu, 03 Jan 2019 12:00:00 EST

Effects of Testosterone on Myocardial Repolarization

Conditions:   Hypogonadism;   Chronic Heart Failure
Intervention:   Drug: Testosterone Undecanoate
Sponsor:   University of Roma La Sapienza
Completed

Mon, 24 Apr 2017 12:00:00 EDT

Testosterone and Physical Function in HIV+ Men

Condition:   HIV Associate Weight Loss
Interventions:   Drug: Testosterone enanthate;   Drug: Placebo
Sponsors:   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK);   Charles Drew University of Medicine and Science
Completed

Thu, 01 Dec 2005 12:00:00 EST

COMbination of Bipolar Androgen Therapy and Nivolumab

Conditions:   Castration-resistant Prostate Cancer;   Metastatic Prostate Cancer;   Prostate Cancer
Interventions:   Drug: Testosterone cypionate;   Drug: Nivolumab
Sponsors:   Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins;   Bristol-Myers Squibb
Active, not recruiting

Wed, 13 Jun 2018 12:00:00 EDT

TESTO: Testosterone Effects on Short-Term Outcomes in Infants With XXY

Condition:   Klinefelter Syndrome
Interventions:   Drug: Testosterone Cypionate 200 Milligram/Milliliter Injectable Solution;   Drug: Placebo injectable saline
Sponsors:   University of Colorado, Denver;   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Active, not recruiting

Mon, 30 Oct 2017 12:00:00 EDT

Exogenous Testosterone Plus Dutasteride for the Treatment of Castrate Metastatic Prostate Cancer

Conditions:   Prostate Cancer;   Castration-resistant, Metastatic
Intervention:   Other: testosterone (AndroGel®) with the 5α-reductase inhibitor dutasteride
Sponsors:   Memorial Sloan Kettering Cancer Center;   GlaxoSmithKline;   University of Washington
Completed

Mon, 02 Mar 2009 12:00:00 EST

A Study of the Effect of Testosterone Replacement Therapy on Blood Pressure in Adult Male Participants With Hypogonadism

Conditions:   Hypogonadism;   Hypogonadism, Male;   Hypogonadotropic Hypogonadism
Intervention:   Drug: Aveed Injectable Product, Fortesta or Testim
Sponsor:   Endo Pharmaceuticals
Recruiting

Thu, 02 Jul 2020 12:00:00 EDT

Quality of Life With TESTIM®

Condition:   Hypogonadism
Intervention:  
Sponsors:   Ferring Pharmaceuticals;   Ferring Arzneimittel GmbH
Completed

Tue, 22 Jun 2010 12:00:00 EDT

The Testosterone Trials in Older Men

Condition:   Andropause
Interventions:   Drug: AndroGel® (testosterone gel);   Drug: Placebo
Sponsors:   University of Pennsylvania;   National Institute on Aging (NIA);   National Institute of Neurological Disorders and Stroke (NINDS);   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD);   National Heart, Lung, and Blood Institute (NHLBI);   Abbott
Completed

Mon, 01 Dec 2008 12:00:00 EST

Testosterone Therapy on Angina Threshold and Atheroma in Patients With Chronic Stable Angina

Condition:   Angina Pectoris
Intervention:   Drug: Nebido
Sponsors:   Sheffield Teaching Hospitals NHS Foundation Trust;   Schering-Plough
Completed

Wed, 17 Aug 2005 12:00:00 EDT

5-Alpha Reductase and Anabolic Effects of Testosterone

Conditions:   Male Hypogonadism;   Muscle Atrophy;   Sarcopenia;   Benign Prostate Hypertrophy
Interventions:   Drug: Testosterone Enanthate;   Drug: Finasteride;   Other: Placebo
Sponsors:   VA Office of Research and Development;   Endo Pharmaceuticals;   Merck Sharp & Dohme Corp.
Completed

Mon, 21 May 2007 12:00:00 EDT

The Effect on Androxal Versus Androgel on Morning Testosterone in Men With Secondary Hypogonadism (Low Testosterone)

Condition:   Secondary Hypogonadism
Interventions:   Drug: Androxal (enclomiphene citrate);   Drug: Testosterone
Sponsor:   Repros Therapeutics Inc.
Completed

Fri, 01 Jul 2011 12:00:00 EDT

Physiological and Psychological Effects of Testosterone During Severe Energy Deficit and Recovery

Conditions:   Caloric Restriction;   Exercise
Interventions:   Drug: Sesame Oil;   Drug: testosterone enanthate
Sponsors:   Pennington Biomedical Research Center;   United States Army Research Institute of Environmental Medicine;   MyoSyntax;   Defence Research and Development Canada;   United States Department of Defense
Completed

Tue, 12 Apr 2016 12:00:00 EDT

The Effect of 90-day Oral Testosterone Therapy in Chinese Males With Type 2 Diabetes (T2DM)

Condition:   Assess the Effects of a the 90-day Oral TS Study Regimen on PSA, IPSS, Haemoglobin and Haematocrit, and to Assess Adverse and Serious Adverse Events.
Intervention:   Drug: Andriol Testocaps
Sponsors:   Singapore Clinical Research Institute;   Singapore General Hospital;   Duke-NUS Graduate Medical School
Terminated

Wed, 18 Jan 2012 12:00:00 EST

Safety and Tolerability of MK0773 in Healthy Older Men (0773-004)

Condition:   Healthy
Interventions:   Drug: MK0773;   Drug: Comparator: testosterone enanthate;   Drug: Comparator: placebo oral tablet;   Drug: Comparator: placebo injection
Sponsor:   Merck Sharp & Dohme Corp.
Completed

Fri, 20 Nov 2009 12:00:00 EST

Testosterone Treatment for Erectile Dysfunction and Multiple Sclerosis

Conditions:   Multiple Sclerosis;   Erectile Dysfunction;   Testosterone Deficiency
Intervention:   Drug: XYOSTED 75 milligram (mg) in 0.5 ML Auto-Injector
Sponsors:   Tulane University;   Louisiana State University Health Sciences Center in New Orleans;   Antares Pharma Inc.
Not yet recruiting

Fri, 23 Oct 2020 12:00:00 EDT

To Evaluate Sperm Parameters in Men With Secondary Hypogonadism Previously Treated With Topical Testosterone

Condition:   Secondary Hypogonadism
Interventions:   Drug: 25 mg Androxal;   Drug: Testim 1%
Sponsor:   Repros Therapeutics Inc.
Completed

Fri, 27 Jun 2008 12:00:00 EDT

The Role of Follicle Stimulating Hormone in Advanced Prostate Cancer

Condition:   Prostate Cancer Recurrent
Interventions:   Drug: Degarelix 120 MG [Firmagon];   Drug: Gonal F RFF Pen 900 UNT Per 1.5 ML Pen Injector;   Drug: Testosterone Undecanoate
Sponsors:   Lund University;   Swedish Cancer Foundation;   ALF Swedish Government Grant
Completed

Tue, 22 Oct 2019 12:00:00 EDT

Study of the Safety, Tolerability and Pharmacokinetics of Testosterone Undecanoate in Hypogonadal Males.

Condition:   Hypogonadal Males
Interventions:   Drug: ABT-SLV361;   Drug: placebo
Sponsor:   Abbott
Completed

Tue, 03 May 2011 12:00:00 EDT

Testosterone for Treating Cachexia in Patients With Squamous Cell Carcinoma

Conditions:   Cachexia;   Squamous Cell Carcinoma
Interventions:   Drug: Placebo Testosterone;   Drug: Testosterone Enanthate 100 MG/ML
Sponsors:   The University of Texas Medical Branch, Galveston;   National Cancer Institute (NCI)
Completed

Thu, 09 Apr 2009 12:00:00 EDT

A Randomized, Double Blind, Placebo-Controlled, Multi-Center Phase III Study in Men With Acquired Hypogonadotropic Hypogonadism to Compare Changes in Testosterone and Sperm Concentration Following Treatment With 12.5 mg or 25 mg Androxal or AndroGel 1.62%

Condition:   Secondary Hypogonadism
Interventions:   Drug: Androxal 12.5 mg or 25 mg;   Drug: AndroGel 1.62%;   Drug: Placebo Capsules;   Drug: Placebo Gel
Sponsor:   Repros Therapeutics Inc.
Completed

Mon, 25 Nov 2013 12:00:00 EST

A Randomized, Double Blind, Placebo-Controlled, Multi-Center Phase III Study in Men With Acquired Hypogonadotropic Hypogonadism to Compare Changes in Testosterone and Sperm Concentration Following Treatment With 12.5 mg or 25 mg Androxal or AndroGel 1.62%

Condition:   Secondary Hypogonadism
Interventions:   Drug: Androxal 12.5 mg/25 mg;   Drug: Placebo Capsules;   Drug: AndroGel 1.62%;   Drug: Placebo Gel
Sponsor:   Repros Therapeutics Inc.
Completed

Mon, 25 Nov 2013 12:00:00 EST

Comparison of Estrogen and Methyltestosterone Combination Treatments for Postmenopausal Hot Flushes

Condition:   Hot Flushes, Menopause, Postmenopause
Intervention:   Drug: Esterified Estrogens (EE) and Methyltestosterone (MT)
Sponsor:   Solvay Pharmaceuticals
Completed

Mon, 12 Sep 2005 12:00:00 EDT

Perioperative Testosterone Replacement Therapy for the Improvement of Post-Operative Outcomes in Patients With Low Testosterone

Conditions:   Hypogonadism;   Malignant Urinary System Neoplasm;   Urinary System Disorder;   Urinary System Neoplasm
Interventions:   Other: Best Practice;   Procedure: Quality-of-Life Assessment;   Other: Questionnaire Administration;   Drug: Testosterone Cypionate
Sponsor:   Emory University
Recruiting

Mon, 01 Feb 2021 12:00:00 EST

Can Testosterone Accelerate Injury Recovery After Arthroscopic Rotator Cuff Repair

Condition:   Rotator Cuff Tears
Interventions:   Drug: Testosterone cypionate;   Drug: Placebos
Sponsor:   Orthopedic Institute, Sioux Falls, SD
Not yet recruiting

Tue, 14 Apr 2020 12:00:00 EDT

Testosterone Therapy for Pubertal Delay in Duchenne Muscular Dystrophy

Condition:   Duchenne Muscular Dystrophy
Intervention:   Drug: Sustanon (testosterone)
Sponsor:   Newcastle-upon-Tyne Hospitals NHS Trust
Completed

Thu, 08 Oct 2015 12:00:00 EDT

Efficacy of Testosterone Gel to Restore Normal Serum Values of Testosterone During the Acute Phase of Critical Illness in Adult ICU Patients

Conditions:   Hypermetabolism in ICU;   Loss of Muscle Mass;   Functional Disability After ICU;   ICU Acquired Hypogonadism;   Treatment With Testosterone Gel in ICU
Intervention:   Drug: AndroGel 16.2 mg/L
Sponsor:   University Hospital, Clermont-Ferrand
Unknown status

Wed, 19 Sep 2018 12:00:00 EDT

Testosterone, Metformin, or Both, for Hypogonadism in Obese Males

Conditions:   Hypogonadism;   Obesity
Interventions:   Drug: Placebo;   Drug: Metformin;   Drug: Testosterone Undecanoate;   Drug: Metformin + Testosterone Undecanoate
Sponsor:   Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud
Completed

Tue, 04 Aug 2015 12:00:00 EDT

Surveillance Study of Women Taking Intrinsa®

Conditions:   Ovariectomy;   Hysterectomy;   Hypoactive Sexual Desire Disorder
Intervention:  
Sponsors:   Center for Epidemiology and Health Research, Germany;   Procter and Gamble
Terminated

Wed, 31 Oct 2007 12:00:00 EDT

Effect of Testosterone Replacement on Exercise Capacity in Hypogonadal Men After a Recent Myocardial Infarction

Conditions:   Hypogonadism;   Acute Myocardial Infarction: Rehabilitation Phase
Interventions:   Drug: Testosterone;   Drug: Normal Saline
Sponsor:   Texas Tech University Health Sciences Center
Withdrawn

Thu, 16 Jun 2016 12:00:00 EDT

The Role of 5-alpha Reductase in Mediating Testosterone Actions

Condition:   Healthy
Interventions:   Drug: Testosterone Enanthate;   Drug: Dutasteride
Sponsor:   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Completed

Fri, 29 Jun 2007 12:00:00 EDT

Cycled Testosterone Therapy to Improve Physical Function in Frail Nursing Home Residents

Condition:   Aging
Interventions:   Drug: Placebo;   Drug: Testosterone
Sponsor:   The University of Texas Medical Branch, Galveston
Terminated

Wed, 10 Feb 2016 12:00:00 EST

Effect of Testosterone Gel Replacement on Fat Mass in Males With Low Testosterone Levels and Diabetes

Conditions:   Hypogonadism;   Diabetes
Interventions:   Drug: Testosterone gel;   Drug: placebo
Sponsors:   Diabetes Center of the Southwest;   Solvay Pharmaceuticals
Withdrawn

Tue, 27 Feb 2007 12:00:00 EST

Evaluation of Testosterone Nasal Gel in Hypogonadal Boys

Condition:   Hypogonadism
Intervention:   Drug: Testosterone Nasal Gel [Natesto]
Sponsor:   Acerus Biopharma Inc.
Unknown status

Fri, 17 Nov 2017 12:00:00 EST

Efficacy and Tolerability of an Intra-Nasal Testosterone Product

Condition:   Hypogonadism
Interventions:   Drug: Nasobol®;   Drug: Androderm® (Positive Control)
Sponsor:   Acerus Pharmaceuticals Corporation
Completed

Fri, 11 Sep 2009 12:00:00 EDT

Multimodality Intervention for Function and Metabolism in SCI

Condition:   Spinal Cord Injuries
Interventions:   Drug: Testosterone Undecanoate;   Behavioral: hybrid exercise
Sponsors:   Brigham and Women's Hospital;   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD);   Spaulding Rehabilitation Hospital
Recruiting

Tue, 03 Jul 2018 12:00:00 EDT

Testosterone and Olaparib in Treating Patients With Castration-Resistant Prostate Cancer

Conditions:   Castration-Resistant Prostate Carcinoma;   Prostate Adenocarcinoma
Interventions:   Other: Laboratory Biomarker Analysis;   Drug: Olaparib;   Other: Quality-of-Life Assessment;   Other: Survey Administration;   Drug: Testosterone Enanthate;   Drug: Testosterone Cypionate
Sponsors:   University of Washington;   National Cancer Institute (NCI);   AstraZeneca
Active, not recruiting

Fri, 04 May 2018 12:00:00 EDT

Vaginal Testosterone Cream For Atrophic Vaginitis in Women Taking Aromatase Inhibitors for Breast Cancer.

Conditions:   Vaginitis;   Dyspareunia;   Breast Neoplasms
Intervention:   Drug: Testosterone propionate
Sponsor:   University of Vermont
Suspended

Thu, 13 May 2010 12:00:00 EDT

Effects of Medications in Patients With Hypogonadism

Condition:   Idiopathic Hypogonadotropic Hypogonadism
Interventions:   Drug: Testosterone enanthate (Sustanon 250 mg);   Drug: Human chorionic gonadotropin (hCG) (Pregnyl 5000 IU);   Drug: Testosteron gel (Testojel 50 mg)
Sponsor:   Gulhane School of Medicine
Completed

Fri, 18 May 2012 12:00:00 EDT

A Pilot Study of Parenteral Testosterone and Oral Etoposide as Therapy for Men With Castration Resistant Prostate Cancer

Condition:   Prostate Cancer
Interventions:   Drug: Testosterone injection;   Drug: Etoposide
Sponsor:   Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Completed

Wed, 10 Mar 2010 12:00:00 EST

Oral T7 Oral Testosterone in Man

Conditions:   Healthy Males;   Male Contraceptive
Interventions:   Drug: First Intervention (7 days);   Other: First Washout (7 days);   Drug: Second Intervention (7 days);   Drug: Third Intervention (7 days);   Other: Second wash-out period
Sponsors:   University of Washington;   National Institutes of Health (NIH);   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Completed

Thu, 12 Feb 2009 12:00:00 EST

TOTEM RRMS : TestOsterone TreatmEnt on Neuroprotection and Myelin Repair in Relapsing Remitting Multiple Sclerosis

Condition:   Multiple Sclerosis, Relapsing-Remitting
Interventions:   Drug: Nebido® Testosterone Undecanoate 1000 Mg/4 mL Solution for Injection;   Drug: Placebo 4 mL Solution for Injection;   Procedure: MRI;   Behavioral: Assessment of impact of MS on cognition; quality of life; fatigue; anxiety/depression and work and activities;   Behavioral: Assessment of disability
Sponsors:   University Hospital, Strasbourg, France;   Bayer;   Fédération Hospitalo-Universitaire NEUROGENYCS
Recruiting

Wed, 10 Apr 2019 12:00:00 EDT

Exercise and Testosterone Therapy in Elderly Men With Physical Frailty

Conditions:   Physical Frailty;   Hip Fracture;   Elective Hip Replacement;   Hypogonadism
Interventions:   Drug: Transdermal Testosterone gel (1%);   Behavioral: Supervised exercise training
Sponsors:   Washington University School of Medicine;   Solvay Pharmaceuticals
Completed

Thu, 29 Jun 2006 12:00:00 EDT

Testosterone Therapy of Men With Type 2 Diabetes Mellitus (T2DM)

Conditions:   Type 2 Diabetes Mellitus;   Hypogonadism
Interventions:   Drug: Testosterone;   Drug: Placebo
Sponsors:   Marianne Andersen;   Odense University Hospital
Completed

Thu, 22 Mar 2012 12:00:00 EDT

Testosterone Replacement in Men With Non-Metastatic Castrate Resistant Prostate Cancer

Condition:   Prostate Cancer
Interventions:   Drug: AndroGel;   Drug: placebo
Sponsors:   University of Chicago;   Solvay Pharmaceuticals
Terminated

Mon, 13 Aug 2007 12:00:00 EDT

A One Year Open Label Study for the Treatment of Hypogonadism (Low Testosterone) in Men Who Have Completed ZA-203

Conditions:   Hypogonadism;   Low Testosterone
Interventions:   Drug: Androxal (enclomiphene citrate);   Drug: Testim (topical testosterone)
Sponsor:   Repros Therapeutics Inc.
Completed

Fri, 01 Jul 2011 12:00:00 EDT

Exercise Training and Testosterone Replacement in Heart Failure Patients

Condition:   Heart Failure
Interventions:   Drug: Testosterone replacement;   Other: Exercise training
Sponsor:   University of Sao Paulo General Hospital
Completed

Tue, 14 May 2013 12:00:00 EDT

Subcutaneous vs. Intramuscular Testosterone

Conditions:   Testosterone Deficiency;   Hypogonadism, Male
Intervention:   Drug: Testosterone
Sponsor:   Men's Health Boston
Completed

Mon, 27 Mar 2017 12:00:00 EDT

Bipolar Androgen-based Therapy for Prostate Cancer (BAT)

Condition:   Recurrent Prostate Cancer
Interventions:   Drug: Testosterone cypionate;   Drug: Goserelin;   Drug: Leuprolide
Sponsor:   Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Completed

Mon, 17 Dec 2012 12:00:00 EST

A Study to Evaluate a Skeletal-muscle Microbiopsy Technique With Dynamic Proteomic Measurement in Healthy Male Volunteers

Condition:   Cachexia
Interventions:   Drug: Deuterated Water;   Drug: Testosterone enanthate;   Drug: Placebo to match testosterone enanthate
Sponsor:   GlaxoSmithKline
Completed

Mon, 14 Oct 2013 12:00:00 EDT

Testosterone Replacement in Male Cancer Survivors With Fatigue and Low Testosterone

Conditions:   Hypogonadism, Male;   Fatigue Syndrome, Chronic
Interventions:   Drug: Testosterone Undecanoate 750 MG/3 ML Intramuscular Solution [AVEED];   Other: placebo
Sponsor:   Seattle Institute for Biomedical and Clinical Research
Recruiting

Thu, 08 Aug 2019 12:00:00 EDT

Effects of Testosterone Replacement on Pain Sensitivity and Pain Perception

Conditions:   Pain;   Hypogonadism
Interventions:   Drug: AndroGel;   Other: Placebo
Sponsor:   Boston University
Completed

Thu, 13 Jul 2006 12:00:00 EDT

The Effects of Long Term Cyclic Testosterone Administration on Muscle Function and Bone in Older Men

Condition:   Sarcopenia
Interventions:   Drug: Testosterone enanthate;   Drug: Placebo
Sponsor:   The University of Texas Medical Branch, Galveston
Withdrawn

Tue, 16 Aug 2011 12:00:00 EDT

Gonadal Dysfunction in Male Long-term Survivors of Malignant Lymphoma; Vitality

Condition:   Hypogonadism
Intervention:   Drug: AndroGel
Sponsors:   Lars Møller Pedersen;   Besins Healthcare;   Copenhagen University Hospital at Herlev;   Zealand University Hospital
Recruiting

Thu, 30 Jul 2020 12:00:00 EDT

Sex-Mismatched Allogeneic Bone Marrow Transplantation for Men With Metastatic Castration-Resistant Prostate Cancer

Condition:   Prostate Cancer
Interventions:   Procedure: Bone marrow transplantation;   Drug: Cytoxan;   Drug: testosterone cypionate
Sponsor:   Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Terminated

Fri, 16 Dec 2016 12:00:00 EST

Neuroendocrine Dysfunction in Traumatic Brain Injury: Effects of Testosterone Therapy

Conditions:   Endocrine Dysfunction;   Trauma;   Brain Injury
Interventions:   Drug: Androgel (Testosterone Gel);   Other: Placebo gel
Sponsors:   Craig Hospital;   University of Colorado, Denver
Completed

Wed, 15 Sep 2010 12:00:00 EDT

Older Men and Testosterone

Condition:   Hypogonadism
Intervention:   Drug: Nebido (Testosterone Undecanoate)
Sponsor:   University Hospital of North Norway
Completed

Wed, 13 Jul 2005 12:00:00 EDT

Testosterone Replacement for Fatigue in Male Hypogonadic Advanced Cancer Patients

Condition:   Advanced Cancer
Interventions:   Drug: Testosterone;   Drug: Placebo
Sponsor:   M.D. Anderson Cancer Center
Completed

Tue, 25 Aug 2009 12:00:00 EDT

Testosterone in Female Hypoactive Sexual Desire Disorder

Condition:   Hypoactive Sexual Desire Disorder
Intervention:   Drug: testosterone gel (Androgel)
Sponsor:   Beersheva Mental Health Center
Completed

Thu, 01 Sep 2005 12:00:00 EDT

Testosterone Replacement Therapy Decreases Plasma Paraoxonase 1 Enzyme Activity In Male Patients With Hypogonadism

Condition:   Hypogonadism
Intervention:   Drug: Sustanon
Sponsor:   Gulhane School of Medicine
Completed

Tue, 20 Apr 2010 12:00:00 EDT

Mechanisms of Hypertension in Women With Polycystic Ovary Syndrome

Conditions:   Polycystic Ovary Syndrome;   Hypertension
Interventions:   Drug: GnRH antagonist;   Drug: GnRH antagonist + MethylTESTOSTERone 5 MG
Sponsor:   Yale University
Enrolling by invitation

Tue, 31 Mar 2020 12:00:00 EDT

Effect of Testosterone on Endothelial Function and Microcirculation in Type 2 Diabetic Patients With Hypogonadism

Conditions:   Type 2 Diabetes;   Hypogonadism
Intervention:   Drug: Testosterone
Sponsor:   Tameside Hospital NHS Foundation Trust
Terminated

Wed, 10 Mar 2010 12:00:00 EST

Effects of Fast Acting Testosterone Nasal Spray on Anxiety

Condition:   Anxiety
Interventions:   Drug: Testosterone;   Drug: Placebo
Sponsor:   University of Texas at Austin
Completed

Wed, 11 Feb 2015 12:00:00 EST

Pharmacokinetic Study of Oral Testosterone (T) Ester Formulations in Hypogonadal Men

Condition:   Hypogonadism
Interventions:   Drug: Oral testosterone undecanoate (TU) (300 mg T equivalents/dose);   Drug: Oral testosterone undecanoate (TU) combined with testosterone enanthate (TE) (400 mg T equivalents/dose);   Drug: Oral testosterone undecanoate (TU) (200 mg T equivalents/dose with and without food);   Drug: Oral testosterone undecanoate (TU) combined with testosterone enanthate (TE) (300 mg T equivalents/dose)
Sponsors:   Clarus Therapeutics, Inc.;   Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Completed

Wed, 11 Jun 2008 12:00:00 EDT

Cycled Testosterone Replacement Study

Condition:   Hypogonadism
Interventions:   Drug: Testosterone;   Drug: Placebo
Sponsor:   The University of Texas Medical Branch, Galveston
Completed

Wed, 12 Aug 2009 12:00:00 EDT

Generation of Biological Samples Positive to Testosterone for Anti-doping Control

Condition:   Healthy Volunteers
Intervention:   Drug: Testosterone injection
Sponsor:   Parc de Salut Mar
Completed

Mon, 23 Dec 2019 12:00:00 EST

A Study to Evaluate the Effect of Testosterone Replacement Therapy (TRT) on the Incidence of Major Adverse Cardiovascular Events (MACE) and Efficacy Measures in Hypogonadal Men

Conditions:   Hypogonadism;   Cardiovascular Diseases
Interventions:   Drug: Testosterone;   Drug: Placebo
Sponsors:   AbbVie;   AbbVie; Acerus Pharmaceuticals Corporation/ Aytu Biosciences Inc.; Allergan Sales LLC; Endo Pharmaceuticals; Upsher-Smith Laboratories LLC
Recruiting

Tue, 08 May 2018 12:00:00 EDT

Testosterone Replacement to Alleviate Pain in Postmenopausal Women (TRAPP Trial)

Conditions:   Pain;   Opioid Use;   Androgen Deficiency
Interventions:   Drug: Testosterone Cypionate;   Drug: Placebo
Sponsor:   Brigham and Women's Hospital
Not yet recruiting

Thu, 20 May 2021 12:00:00 EDT

Pain Alleviation With Testosterone in Opioid-Induced Hypogonadism

Conditions:   Opioid Use;   Pain;   Hypogonadism, Male
Interventions:   Drug: Testosterone cypionate;   Drug: Placebo
Sponsor:   Brigham and Women's Hospital
Not yet recruiting

Mon, 15 Mar 2021 12:00:00 EDT

Effect of Testosterone Replacement on Insulin Resistance

Conditions:   Metabolic Syndrome;   Hypogonadism
Interventions:   Radiation: Testosterone gel;   Drug: Placebo for testosterone gel
Sponsors:   McGuire Research Institute;   Solvay Pharmaceuticals
Completed

Tue, 19 Jun 2007 12:00:00 EDT

Use of Testosterone to Prevent Post-Surgical Muscle Loss - Pilot Study

Conditions:   Muscle Atrophy;   Surgery;   Knee Injuries and Disorders;   Complication of Surgical Procedure;   Trauma
Interventions:   Drug: Aveed 750 MG in 3 ML IM Injection;   Other: Normal Saline 3 ML IM Injection
Sponsor:   The Stone Research Foundation for Sports Medicine and Arthritis
Enrolling by invitation

Thu, 02 Jul 2020 12:00:00 EDT

Testosterone Pellets Plus Vitamin D and E Versus Vitamin D and E Alone for the Treatment of Peyronie's Disease

Condition:   Peyronie's Disease
Interventions:   Drug: Vitamin D2;   Drug: Vitamin E;   Drug: Testosterone Pellets
Sponsor:   Men's Health Boston
Completed

Tue, 17 Apr 2012 12:00:00 EDT

Subcutaneous Testosterone Project

Condition:   Gender Dysphoria
Intervention:   Drug: Subcutaneous testosterone
Sponsors:   University of British Columbia;   Vancouver Coastal Health Research Institute
Completed

Mon, 01 Sep 2014 12:00:00 EDT

Study of the Efficacy of ESTRATEST® H.S. Tablets in Relieving Menopausal Symptoms in Estrogenized Postmenopausal Women

Condition:   Menopause
Intervention:   Drug: esterified estrogens 0.625 mg and methyltestosterone 1.25 mg
Sponsor:   Solvay Pharmaceuticals
Completed

Thu, 01 Sep 2005 12:00:00 EDT

Evaluate the Pharmacokinetics and Gonadotropin Suppression of Nestorone®-Testosterone (NES/T) Combination Gel in Men

Condition:   Healthy
Interventions:   Drug: Nestorone® /testosterone gel;   Drug: Testosterone only gel
Sponsors:   Health Decisions;   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Completed

Mon, 04 May 2015 12:00:00 EDT

Reandron in Diabetic Men Witn Low Testosterone Level

Conditions:   Type 2 Diabetes;   Hypogonadism
Interventions:   Drug: Reandron 1000;   Drug: placebo
Sponsor:   Austin Health
Completed

Wed, 13 Feb 2008 12:00:00 EST

Effect of Transgender Therapy on Muscle, Fat and Tissue Receptors

Conditions:   Gender Incongruence;   Transgenderism
Interventions:   Drug: testosterone cypionate;   Drug: Estradiol Valerate
Sponsor:   St. Louis University
Active, not recruiting

Wed, 16 Sep 2020 12:00:00 EDT

The Effects of Testosterone on Prostate Tissue (ACYP-1)

Conditions:   Hypogonadism;   Contraception
Interventions:   Drug: Testosterone gel;   Drug: Acyline;   Drug: Placebo acyline;   Drug: Placebo Testosterone gel
Sponsors:   University of Washington;   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Completed

Mon, 12 Sep 2005 12:00:00 EDT

Normalization of Morning Testosterone Levels in Men With Secondary Hypogonadism

Condition:   Secondary Hypogonadism
Interventions:   Drug: Placebo;   Drug: topical testosterone;   Drug: Androxal
Sponsor:   Repros Therapeutics Inc.
Completed

Wed, 05 Jan 2011 12:00:00 EST

Testosterone Replacement Therapy in Advanced Chronic Kidney Disease

Conditions:   Kidney Failure;   Kidney Diseases
Intervention:   Drug: Testim (1% testosterone gel)
Sponsor:   Stanford University
Completed

Fri, 28 Mar 2008 12:00:00 EDT

Plasma RBP Levels in Patients With Idiopathic Hypogonadotrophic Hypogonadism

Condition:   Idiopathic Hypogonadotropic Hypogonadism
Intervention:   Drug: Sustanon 250 mg ampule (Testosterone esters)
Sponsor:   Gulhane School of Medicine
Completed

Tue, 01 Jan 2013 12:00:00 EST

Compromised Microcirculation in Women With Polycystic Ovary Syndrome

Condition:   Polycystic Ovary Syndrome
Interventions:   Drug: ganirelix acetate;   Drug: methyl testosterone
Sponsors:   Yale University;   National Heart, Lung, and Blood Institute (NHLBI)
Completed

Tue, 23 Sep 2008 12:00:00 EDT

Transdermal Testosterone Gel/Effect on Erection Quality as Measured by DIR

Condition:   Hypogonadism
Intervention:   Drug: AndroGel (Transdermal Testosterone Gel)
Sponsors:   Lamm, Steven, M.D.;   Solvay Pharmaceuticals
Completed

Tue, 23 Jan 2007 12:00:00 EST

Co-Administering Testosterone With PDE5 Inhibitors in ED Patients Non Responders to PDE5 Inhibitors Alone

Conditions:   Erectile Dysfunction;   Hypogonadism
Interventions:   Drug: Testosterone gel;   Drug: testosterone;   Other: placebo gel
Sponsors:   SELARL du Dr Jacques BUVAT;   Bayer
Completed

Tue, 25 Oct 2005 12:00:00 EDT

Testosterone and Its Metabolites in GID

Condition:   Transsexualism
Interventions:   Drug: testosterone undecanoate alone;   Drug: testosterone undecanoate plus letrozole;   Drug: testosterone undecanoate plus dutasteride
Sponsors:   Unita Complessa di Ostetricia e Ginecologia;   Schering-Plough
Completed

Mon, 05 Sep 2005 12:00:00 EDT

Ambulatory Blood Pressure Monitoring (ABPM) Extension Study of Oral Testosterone Undecanoate in Hypogonadal Men

Condition:   Hypogonadism, Male
Intervention:   Drug: SOV2012-F1
Sponsors:   Marius Pharmaceuticals;   Syneos Health
Completed

Mon, 13 Jul 2020 12:00:00 EDT

Steady-State Feedback Actions of Testosterone on Luteinizing Hormone Secretion in Young and Older Men

Condition:   Hypogonadism
Intervention:   Drug: Ketoconazole, Dexamethesone, Androgel,GnRH
Sponsors:   Mayo Clinic;   National Institutes of Health (NIH)
Completed

Mon, 05 Feb 2007 12:00:00 EST

Anabolic and Inflammatory Responses to Short-Term Testosterone Administration in Older Men

Condition:   Sarcopenia
Interventions:   Drug: Testosterone injection;   Drug: Testosterone gel;   Drug: Medrol
Sponsor:   The University of Texas Medical Branch, Galveston
Completed

Wed, 12 Aug 2009 12:00:00 EDT

The Effect of Testosterone Replacement on Endothelial Dysfunction, Inflammation and Insulin Resistance in Male Hypogonadotrophic Hypogonadism

Condition:   Hypogonadotrophic Hypogonadism
Interventions:   Drug: Testogel 50 mg transdermal gel;   Drug: Testosterone 250mg injection
Sponsor:   Gulhane School of Medicine
Completed

Wed, 15 Feb 2012 12:00:00 EST

Dose-Response of Gonadal Steroids and Bone Turnover in Older Men

Condition:   Healthy Volunteers
Interventions:   Drug: Testosterone;   Drug: Goserelin acetate
Sponsors:   Massachusetts General Hospital;   National Institute on Aging (NIA);   Solvay Pharmaceuticals;   AstraZeneca;   AbbVie
Completed

Tue, 14 Jun 2005 12:00:00 EDT

TEAM: Testosterone Supplementation and Exercise in Elderly Men

Condition:   Healthy
Interventions:   Drug: LowT;   Behavioral: Resistance Training;   Drug: Placebo;   Drug: HighT
Sponsors:   University of Colorado, Denver;   National Institute on Aging (NIA)
Completed

Mon, 30 May 2005 12:00:00 EDT

Study of Exposure to Substances Prohibited by the World Anti-Doping Agency in Healthy Volunteers.

Condition:   Healthy Volunteers
Interventions:   Drug: Bupropion;   Drug: Anastrozole;   Drug: Testosterone cyclopentylpropionate;   Drug: Danazol;   Drug: Chlorthalidone
Sponsor:   Parc de Salut Mar
Completed

Wed, 17 Feb 2021 12:00:00 EST

Testosterone Replacement Therapy and Liraglutide Effects on Weight Loss in Hypogonadism.

Conditions:   Hypogonadism;   Obesity
Interventions:   Drug: liraglutide;   Drug: Testosterone
Sponsor:   University Medical Centre Ljubljana
Completed

Tue, 07 Aug 2018 12:00:00 EDT

Testosterone and Neurovascular Control in Humans

Condition:   Healthy
Interventions:   Drug: Cetrorelix Acetate;   Drug: Testosterone gel
Sponsor:   Western University, Canada
Not yet recruiting

Fri, 26 Mar 2021 12:00:00 EDT

Effect of Increasing Testosterone on Insulin Sensitivity in Men With the Metabolic Syndrome

Condition:   Metabolic Syndrome
Interventions:   Drug: Zoladex;   Drug: Testosterone gel;   Drug: Anastrozole Pill;   Other: Placebo
Sponsors:   Massachusetts General Hospital;   National Institutes of Health (NIH);   American Diabetes Association
Terminated

Thu, 22 Feb 2007 12:00:00 EST

Testosterone Treatment in a Patient With 17β-hydroxysteroid Dehydrogenase Type 3 Deficiency: an N-of-1 Study

Condition:   Disorder of Sex Development, 46,XY
Interventions:   Drug: Testosterone gel;   Drug: Placebo
Sponsor:   Erasmus Medical Center
Not yet recruiting

Mon, 05 Apr 2021 12:00:00 EDT

Testosterone Therapy and Bone Quality in Men With Diabetes and Hypogonadism

Conditions:   Type 2 Diabetes Mellitus;   Hypogonadism
Interventions:   Drug: Testosterone gel 1.62%;   Drug: Placebo
Sponsor:   VA Office of Research and Development
Recruiting

Mon, 25 Mar 2019 12:00:00 EDT

Testosterone Therapy in Hypogonadal Men Treated With Opioids

Condition:   Hypogonadism
Interventions:   Drug: Testosterone;   Drug: placebo
Sponsor:   Marianne Andersen
Completed

Tue, 05 May 2015 12:00:00 EDT

Intranasal Delivery of Testosterone and Its Effect on Doping Markers

Condition:   Abuse of Anabolic Steroids
Intervention:   Drug: Testosterone
Sponsors:   University of Utah;   Sports Medicine Research and Testing Laboratory;   Partnership for Clean Competition
Completed

Fri, 20 Nov 2015 12:00:00 EST

Effect of Varying Testosterone Levels on Insulin Sensitivity in Men With Idiopathic Hypogonadotropic Hypogonadism (IHH)

Conditions:   Hypogonadotropic Hypogonadism;   Kallmann Syndrome
Interventions:   Drug: Anastrozole Pill;   Drug: Testosterone;   Drug: Placebo Oral Tablet
Sponsor:   Massachusetts General Hospital
Terminated

Tue, 18 Apr 2017 12:00:00 EDT

Testosterone and Pain Sensitivity

Conditions:   Low Testosterone;   Hypogonadism;   Pain
Interventions:   Drug: Testosterone Gel;   Drug: Placebo Gel
Sponsors:   Johns Hopkins University;   Endo Pharmaceuticals
Withdrawn

Fri, 21 Sep 2012 12:00:00 EDT

A Study to Investigate Biomarkers of Skin Androgenization Following Testosterone Administration (0000-015)(COMPLETED).

Condition:   Skin Androgenization
Interventions:   Drug: testosterone gel;   Drug: Comparator: placebo
Sponsor:   Merck Sharp & Dohme Corp.
Completed

Tue, 01 Sep 2009 12:00:00 EDT

NES Gel-1, To Evaluate Nestorone Gel in Combination With Testosterone Gel

Condition:   Contraception
Interventions:   Drug: Nestorone gel;   Drug: Testosterone Gel
Sponsors:   University of Washington;   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Completed

Thu, 29 Sep 2005 12:00:00 EDT

Effects of Testosterone Gel on Carbohydrate and Lipid Metabolism In Elderly Obese Men

Conditions:   Aging;   Obesity;   Insulin Resistance;   Hypogonadism
Intervention:   Drug: Topical testosterone gel 10 g/day
Sponsors:   University of Southern California;   Solvay Pharmaceuticals
Completed

Thu, 17 Aug 2006 12:00:00 EDT

TOM: Testosterone in Older Men With Sarcopenia

Conditions:   Sarcopenia;   Hypogonadism;   Muscular Diseases
Interventions:   Drug: Topical testosterone gel 1% (active formulation);   Drug: Topical gel (placebo formulation)
Sponsors:   Boston Medical Center;   National Institute on Aging (NIA)
Terminated

Tue, 18 Oct 2005 12:00:00 EDT

The Effect of Testosterone on Mood and Quality of Life

Conditions:   Gonadal Disorders;   Depressive Disorder;   Hypogonadism
Intervention:   Drug: Testosterone gel
Sponsors:   Seattle Institute for Biomedical and Clinical Research;   American Federation for Aging Research;   VA Puget Sound Health Care System;   Geriatric Research Education and Clinical Care;   University of Washington;   Solvay Pharmaceuticals
Completed

Tue, 20 Sep 2005 12:00:00 EDT

Feasibility Study of Post-hospitalization Interventions to Improve Physical Function in Older Adults

Condition:   Aging
Interventions:   Drug: Placebo;   Dietary Supplement: Nutritional Supplement;   Behavioral: In-home exercise;   Drug: Testosterone
Sponsors:   The University of Texas Medical Branch, Galveston;   Dairy Research Institute;   National Dairy Council
Completed

Wed, 30 Jul 2014 12:00:00 EDT

TRADE-Testosterone Replacement and Dutasteride Effectiveness

Conditions:   Hypogonadism;   Benign Prostatic Hyperplasia
Interventions:   Drug: Dutasteride;   Drug: Testosterone gel;   Drug: Placebo dutasteride
Sponsors:   University of Washington;   GlaxoSmithKline;   Seattle Institute for Biomedical and Clinical Research;   VA Office of Research and Development;   Solvay Pharmaceuticals
Completed

Mon, 19 Sep 2005 12:00:00 EDT

Treatment of Sexual Dysfunction in Hypogonadal Men With Epilepsy With Testosterone and Either Anastrozole or Placebo

Conditions:   Seizure Disorder;   Hypogonadism;   Erectile Dysfunction
Interventions:   Drug: Anastrozole 1mg;   Drug: Placebo Oral Tablet
Sponsors:   Beth Israel Deaconess Medical Center;   AstraZeneca
Completed

Fri, 16 Sep 2005 12:00:00 EDT

Influence of Male Hormones on Regional Fat Metabolism

Condition:   Obesity
Interventions:   Drug: Leuprolide;   Drug: Testosterone
Sponsors:   Mayo Clinic;   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK);   Abbott
Completed

Mon, 12 Jul 2010 12:00:00 EDT

The Efficacy of ESTRATEST® Tablets in Relieving Menopausal Symptoms in Estrogenized, Hysterectomized Postmenopausal Women

Condition:   Menopause
Interventions:   Drug: esterified estrogens 1.25mg and methyltestosterone 2.5mg;   Drug: Esterified estrogens 1.25 mg
Sponsor:   Solvay Pharmaceuticals
Terminated

Thu, 01 Sep 2005 12:00:00 EDT

The Efficacy of ESTRATEST® Tablets in Relieving Menopausal Symptoms in Estrogenized, Non-Hysterectomized Postmenopausal Women

Condition:   Menopause
Interventions:   Drug: esterified estrogens 1.25 mg and methyltestosterone 2.5 mg;   Drug: Esterified estrogens 1.25 mg
Sponsor:   Solvay Pharmaceuticals
Terminated

Thu, 01 Sep 2005 12:00:00 EDT

Study of Psychological and Motor Effects of Testosterone in Adolescents With XXY/Klinefelter Syndrome

Conditions:   Klinefelter Syndrome;   XXY Syndrome
Interventions:   Drug: Testosterone gel 1%;   Drug: Placebo gel
Sponsors:   University of Colorado, Denver;   Colorado Clinical & Translational Sciences Institute;   Children's Hospital Colorado;   National Institute of Neurological Disorders and Stroke (NINDS)
Completed

Thu, 26 Apr 2012 12:00:00 EDT

Testosterone Therapy in Heart Failure

Conditions:   Heart Failure;   Hypogonadism
Interventions:   Drug: testerone gel;   Drug: Placebo
Sponsors:   Cedars-Sinai Medical Center;   Abbott
Withdrawn

Tue, 21 Jun 2011 12:00:00 EDT

Testosterone for Fatigue in Men With MS

Condition:   Multiple Sclerosis
Interventions:   Drug: AndroGel 1 % Topical Gel;   Drug: Placebos
Sponsors:   University of California, Los Angeles;   Washington University School of Medicine
Withdrawn

Wed, 21 Dec 2016 12:00:00 EST

T-IR- Study to Understand the Effects of Testosterone and Estrogen on the Body's Response to the Hormone Insulin

Conditions:   Insulin Resistance;   Type 2 Diabetes Mellitus;   Obesity;   Androgen Deficiency;   Metabolic Disease
Interventions:   Drug: Acyline;   Drug: Testosterone 1.62% gel;   Drug: Letrozole;   Drug: Placebo gel (for Testosterone 1.62% gel);   Drug: Placebo pill (for Letrozole)
Sponsor:   University of Washington
Completed

Tue, 18 Sep 2012 12:00:00 EDT

Effect of Testosterone Pretreatment in POR

Condition:   Infertility
Intervention:   Drug: Testosterone gel
Sponsors:   Hanoi Medical University;   National Hospital of Obstetrics and Gynecology
Completed

Mon, 26 Oct 2020 12:00:00 EDT

Systemic Hormones and Muscle Protein Synthesis

Conditions:   Sarcopenia;   Muscle Hypotrophy;   Muscle Atrophy
Interventions:   Drug: Sustanon 250;   Drug: Zoladex;   Other: Placebo
Sponsor:   University of Nottingham
Unknown status

Wed, 15 Feb 2017 12:00:00 EST

Bone Loss in Women With Anorexia Nervosa

Condition:   Anorexia Nervosa
Interventions:   Drug: Testosterone;   Drug: Actonel (risedronate);   Drug: Placebo Actonel (risedronate);   Drug: Placebo testosterone
Sponsors:   Massachusetts General Hospital;   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK);   National Center for Research Resources (NCRR)
Completed

Tue, 17 Aug 2004 12:00:00 EDT

Testosterone TRANSdermal Gel for Poor Ovarian Responders Trial

Conditions:   Infertility;   Poor Ovarian Response
Interventions:   Drug: Testosterone gel;   Drug: Placebo gel
Sponsor:   Institut Universitari Dexeus
Recruiting

Thu, 16 Apr 2015 12:00:00 EDT

Testosterone and Growth Hormone for Bone Loss in Men

Conditions:   Hypopituitarism;   Hypogonadism;   Growth Hormone Deficiency
Interventions:   Drug: Testosterone plus somatropin;   Drug: testosterone
Sponsors:   University of Pennsylvania;   National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Completed

Tue, 06 Apr 2004 12:00:00 EDT

Testosterone Replacement in Older Men and Atherosclerosis Progression

Conditions:   Hypogonadism;   Atherosclerosis
Interventions:   Drug: Testosterone Gel (Androgel);   Drug: Placebo
Sponsors:   Brigham and Women's Hospital;   Solvay Pharmaceuticals
Completed

Tue, 07 Feb 2006 12:00:00 EST

Study to Evaluate the Safety and Efficacy of Androxal™ Treatment in Men With Secondary Hypogonadism

Condition:   Secondary Hypogonadism
Interventions:   Drug: Androxal;   Drug: AndroGel;   Drug: Placebo
Sponsor:   Repros Therapeutics Inc.
Completed

Thu, 20 Aug 2009 12:00:00 EDT

Comparison Between Testosterone and Estradiol Over the Homogenization of Follicular Cohort

Condition:   Fertility Disorders
Interventions:   Drug: Testosterone;   Drug: Estradiol
Sponsor:   Hospital de Clinicas de Porto Alegre
Unknown status

Thu, 03 Aug 2017 12:00:00 EDT

Testosterone Gel in Poor Responders Undergoing IVF

Condition:   Infertility
Interventions:   Drug: Testosterone gel;   Drug: DHEA
Sponsors:   Vietnam National University;   Mỹ Đức Hospital
Withdrawn

Tue, 15 Sep 2015 12:00:00 EDT

Novel Approaches for Minimizing Drug-Induced QT Interval Lengthening

Conditions:   Long QT Syndrome;   Abnormalities, Drug-Induced
Interventions:   Drug: Progesterone;   Drug: Ibutilide;   Drug: Testosterone;   Drug: Placebo
Sponsors:   Indiana University;   Purdue University;   National Heart, Lung, and Blood Institute (NHLBI);   Harvard University;   Cedars-Sinai Medical Center
Not yet recruiting

Sat, 19 Dec 2020 12:00:00 EST

A Study of Effect of Deodorant and Axillary Hair on Testosterone Absorption in Healthy Participants

Condition:   Healthy Participants
Interventions:   Drug: Testosterone;   Other: Deodorant Spray;   Other: Deodorant and Antiperspirant Combination Spray;   Other: Deodorant and Antiperspirant Combination Stick
Sponsor:   Eli Lilly and Company
Completed

Mon, 12 Nov 2012 12:00:00 EST

A Study of Ejaculatory Dysfunction in Men With Low Testosterone Levels

Conditions:   Ejaculatory Dysfunction;   Hypogonadism
Interventions:   Drug: Testosterone Solution 2%;   Drug: Placebo Solution
Sponsor:   Eli Lilly and Company
Completed

Thu, 18 Aug 2011 12:00:00 EDT

Testosterone Replacement in Metabolic Syndrome and Inflammation

Conditions:   Hypogonadism;   Metabolic Syndrome;   Obesity;   Erectile Dysfunction
Interventions:   Drug: Testosterone;   Drug: Placebo
Sponsor:   University of Roma La Sapienza
Completed

Fri, 14 May 2010 12:00:00 EDT

Male Hormonal Contraceptive Development-ACY-5

Condition:   Contraception
Interventions:   Drug: Acyline;   Drug: Testosterone Gel;   Drug: Depo-Medroxyprogesterone
Sponsors:   University of Washington;   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD);   CONRAD
Completed

Mon, 12 Sep 2005 12:00:00 EDT

Manipulation of the Intratesticular Hormonal Milieu With Exogenous Testosterone (HOP 5) Testicular Aspiration Addendum

Condition:   Contraception
Interventions:   Drug: Acyline;   Drug: Testosterone Gel;   Drug: Depo-Medroxyprogesterone
Sponsors:   University of Washington;   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Completed

Mon, 12 Sep 2005 12:00:00 EDT

A Study of the Pharmacokinetics of Testosterone Metered Dose (MD)-Lotion Formulations

Condition:   Hypogonadism
Intervention:   Drug: Testosterone MD-Lotion
Sponsor:   Eli Lilly and Company
Completed

Mon, 09 Mar 2009 12:00:00 EDT

A Trial to Evaluate the Ongoing Skin Safety of Testosterone MD-Lotion Formulations

Condition:   Hypogonadism
Intervention:   Drug: Testosterone MD-Lotion
Sponsor:   Eli Lilly and Company
Completed

Fri, 06 Mar 2009 12:00:00 EST

A Titration Trial to Determine the Effectiveness of Testosterone MD-Lotion (Cutaneous Solution) Formulations

Condition:   Hypogonadism
Intervention:   Drug: Testosterone MD-Lotion
Sponsor:   Eli Lilly and Company
Completed

Fri, 20 Jun 2008 12:00:00 EDT

Constitutional Delay of Growth and Puberty: Towards Evidence-based Treatment

Condition:   Constitutional Delay of Growth and Puberty
Interventions:   Drug: Testosterone;   Drug: Letrozole
Sponsors:   Helsinki University Central Hospital;   Foundation for Paediatric Research, Finland
Completed

Fri, 22 Feb 2013 12:00:00 EST

A Study in Men With Low Testosterone to Measure the Effects of Testosterone Solution on Testosterone Levels, Sex Drive and Energy

Condition:   Hypogonadism
Interventions:   Drug: Testosterone Solution;   Drug: Placebo Solution
Sponsor:   Eli Lilly and Company
Completed

Fri, 22 Mar 2013 12:00:00 EDT

The Effect of Testosterone Topical Solution (LY900011) in Hypogonadal Men With Suboptimal Response to a Topical Testosterone Gel

Condition:   Hypogonadism
Intervention:   Drug: Topical Testosterone Solution
Sponsor:   Eli Lilly and Company
Completed

Tue, 09 Jul 2013 12:00:00 EDT

PROS-1-Male Hormonal Contraceptive Regimens on Prostate Tissue

Condition:   Healthy
Interventions:   Drug: Testosterone gel;   Drug: Dutasteride;   Drug: Depo-Medroxyprogesterone (DMPA);   Other: Placebo Testosterone gel;   Other: Placebo dutasteride;   Other: Placebo DMPA
Sponsors:   University of Washington;   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Completed

Fri, 22 Jun 2007 12:00:00 EDT

Hormonal Mechanisms of Sleep Restriction

Condition:   Insulin Resistance
Interventions:   Drug: Ketoconazole;   Drug: Hydrocortisone;   Drug: Testosterone;   Drug: Placebo for ketoconazole;   Drug: Placebo for hydrocortisone;   Drug: Placebo for testosterone
Sponsor:   Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Active, not recruiting

Mon, 06 Oct 2014 12:00:00 EDT

Effect of Testosterone in Men With Erectile Dysfunction

Conditions:   Erectile Dysfunction;   Testosterone Deficiency;   Diabetes
Interventions:   Drug: Sildenafil citrate (open label);   Drug: Testosterone gel;   Other: Placebo gel
Sponsors:   Boston University;   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Completed

Wed, 08 Aug 2007 12:00:00 EDT

Muscle Anabolic Interventions to Accelerate Recovery From Hospitalization in Geriatric Patients

Condition:   Aging
Interventions:   Drug: Testosterone;   Dietary Supplement: Protein Supplement;   Other: Placebo Injection;   Other: Placebo supplement
Sponsor:   The University of Texas Medical Branch, Galveston
Active, not recruiting

Tue, 13 Dec 2016 12:00:00 EST

Effects of Aromatase Inhibition Versus Testosterone in Older Men With Low Testosterone: Randomized-Controlled Trial.

Conditions:   Hypogonadism;   Diabetes;   Sarcopenia;   Osteoporosis;   Depression
Interventions:   Drug: Androgel (Testosterone Gel);   Drug: Anastrozole (Aromatase Inhibitor);   Drug: Placebo tablet;   Drug: Placebo gel;   Dietary Supplement: Calcium Cardone 500mg with vitamin D 400 IU
Sponsor:   National Institute on Aging (NIA)
Completed

Wed, 02 Mar 2005 12:00:00 EST

IRAD2 : Patients With Respiratory Failure at Home

Conditions:   Chronic Respiratory Failure;   Nutritional Depletion
Interventions:   Behavioral: education;   Drug: Oral dietary supplements (563 kcal/d), RESPIFOR;   Behavioral: exercises on an ergometric bicycle 3 to 5 times a week;   Drug: 160 mg/d of oral testosterone undecanoate in men, 80 mg/d in women
Sponsors:   University Hospital, Grenoble;   Societe Francophone de Nutrition Enterale et Parenterale;   Association ANTADIR ,;   Ministry of Health, France;   Association AGIR à Dom,;   Nutricia France, swizerland),;   Organon
Completed

Mon, 03 Oct 2005 12:00:00 EDT

Sex Steroids and the Serotonin Transporter

Condition:   Transsexualism
Interventions:   Drug: Testolactone undecanoate;   Drug: Lynestrenol;   Drug: Cyproterone Acetate;   Drug: Estradiol;   Drug: 5-alpha reductase inhibitor
Sponsor:   Medical University of Vienna
Completed

Tue, 09 Feb 2010 12:00:00 EST

Time to Eugonadal Range, Time to Steady State and Drying Time

Condition:   Male Hypogonadism
Intervention:   Drug: testosterone gel 2%
Sponsor:   Endo Pharmaceuticals
Completed

Mon, 25 Oct 2010 12:00:00 EDT

The Effect of Combination of Red and White Bahman Retrieved of Iranian Traditional Medicine on Semen Parameters in Idiopathic Oligospermic Men

Condition:   Infertility, Male
Interventions:   Drug: Bahman capsules;   Drug: Placebo
Sponsor:   Royan Institute
Unknown status

Tue, 20 Dec 2016 12:00:00 EST

Sex Hormone Dysregulations Are Associated With Critical Illness in COVID-19 Patients

Conditions:   Covid19;   Critical Illness
Intervention:   Diagnostic Test: Sex Hormones
Sponsors:   Universitätsklinikum Hamburg-Eppendorf;   Federal Ministry of Health, Germany
Completed

Tue, 27 Jul 2021 12:00:00 EDT

Efficacy and Safety of Testosterone Therapy in Improving Sarcopenia in Men With Cirrhosis.

Condition:   Liver Cirrhosis
Interventions:   Drug: Testosterone Supplementation;   Drug: Standard Medical Treatment;   Other: Exercise
Sponsor:   Institute of Liver and Biliary Sciences, India
Unknown status

Mon, 24 Jun 2019 12:00:00 EDT

Docetaxel With Rapid Hormonal Cycling as a Treatment for Patients With Prostate Cancer

Condition:   Prostate Cancer
Interventions:   Drug: GnRh (Leuprolide);   Drug: Testosterone Gel;   Drug: Docetaxel
Sponsor:   Memorial Sloan Kettering Cancer Center
Completed

Mon, 07 Jan 2008 12:00:00 EST

TRT in Combination With Electrical Stimulation and Standing: Effect on Muscle and Bone in Spinal Cord Injured Males

Condition:   Spinal Cord Injury
Interventions:   Drug: Testosterone Gel applied by a pump;   Other: Stand Training;   Device: Electrical Stimulation
Sponsors:   Kessler Foundation;   United States Department of Defense
Recruiting

Tue, 16 Dec 2014 12:00:00 EST

Sex Steroids, Sleep, and Metabolic Dysfunction in Women

Conditions:   Polycystic Ovary Syndrome (PCOS);   Obstructive Sleep Apnea;   Obesity
Interventions:   Drug: Progesterone;   Drug: testosterone;   Drug: glucocorticoid;   Device: continuous positive airway pressure;   Drug: Estrogen;   Other: Control
Sponsor:   Washington University School of Medicine
Completed

Tue, 09 Dec 2008 12:00:00 EST

ITT-5 Mechanisms of Spermatogenesis in Man

Condition:   Gonadotropin Deficiency
Interventions:   Drug: Testosterone 1% Gel;   Drug: Acyline;   Drug: Dutasteride;   Drug: Ketoconazole;   Drug: HCG;   Drug: placebo dutasteride;   Drug: placebo ketoconazole
Sponsor:   University of Washington
Withdrawn

Wed, 28 May 2014 12:00:00 EDT

PROS-2 Dose Response Effects of Exogenous Testosterone on the Prostate

Condition:   Healthy
Interventions:   Other: placebo acyline;   Other: placebo gel;   Drug: Testosterone 1% gel 1.25 g;   Drug: Testosterone 1% gel 2.5 g;   Drug: Testosterone 1% gel 5.0 g;   Drug: testosterone 1% gel 10 g;   Drug: testosterone 1% gel 15 g;   Drug: Acyline
Sponsors:   University of Washington;   National Institutes of Health (NIH);   National Institute on Aging (NIA)
Completed

Fri, 01 Apr 2011 12:00:00 EDT

A Study of the Safety and Tolerability of LPCN 1144 in Subjects Who Completed the LPCN 1144-18-002 Trial

Condition:   NASH - Nonalcoholic Steatohepatitis
Intervention:   Drug: LPCN 1144
Sponsor:   Lipocine Inc.
Enrolling by invitation

Mon, 28 Dec 2020 12:00:00 EST

Influence of Testosterone Administration on Drug-Induced QT Interval Prolongation and Torsades de Pointes

Condition:   Long QT Syndrome
Interventions:   Drug: Testosterone;   Drug: Progesterone;   Drug: Placebo;   Drug: Ibutilide
Sponsors:   Indiana University;   American Heart Association;   Purdue University
Completed

Mon, 03 Aug 2015 12:00:00 EDT

Extracellular Vesicles and Endothelial Function in Transgender Subjects

Condition:   Transgenderism
Interventions:   Drug: gender affirming hormonal treatment in transgender men;   Drug: gender affirming hormonal treatment in transgender women
Sponsor:   Central Hospital, Nancy, France
Not yet recruiting

Wed, 21 Jul 2021 12:00:00 EDT

Study of the Effect of Testosterone and Estradiol on NP Responses to Acute and Chronic Salt Loading

Condition:   Hypertension
Interventions:   Drug: leuprolide acetate;   Drug: Anastrozole
Sponsor:   Massachusetts General Hospital
Withdrawn

Wed, 09 Jan 2013 12:00:00 EST

Fluids Administration During Combined Clonidine-Arginine Growth Hormone Stimulation Test

Condition:   Growth Hormone Deficiency
Intervention:   Procedure: 9% Sodium Chloride (NaCl) IV
Sponsor:   Rabin Medical Center
Not yet recruiting

Fri, 10 Jul 2020 12:00:00 EDT

Testosterone and Alendronate in Hypogonadal Men

Conditions:   Hypogonadism;   Osteopenia;   Osteoporosis
Interventions:   Drug: Testosterone;   Drug: Alendronate;   Drug: Placebo Alendronate;   Drug: Placebo Testosterone
Sponsors:   Massachusetts General Hospital;   Endo Pharmaceuticals;   Merck Sharp & Dohme Corp.
Suspended

Thu, 27 Oct 2011 12:00:00 EDT

Testosterone-Dependent Effects on Protein Biomarkers From Healthy Males

Condition:   Hypogonadism, Male
Intervention:   Drug: GnRH antagonist
Sponsor:   Lund University
Completed

Wed, 30 May 2018 12:00:00 EDT

Periodontal Profile of Hypogonadic Men

Conditions:   Periodontitis;   Hypogonadism, Male
Interventions:   Drug: Testosterone gel;   Drug: Placebos
Sponsors:   Universidade Federal do Paraná;   Universidade Estadual Paulista - UNESP;   Universidade de Guarulhos
Withdrawn

Mon, 05 Jun 2017 12:00:00 EDT

Prevention of Recurrent UTI Using Vaginal Testosterone Versus Placebo Placebo

Conditions:   Recurrent Urinary Tract Infection;   Vaginal Atrophy;   Postmenopausal Disorder
Intervention:   Drug: Vaginal Cream with Applicator
Sponsors:   Maimonides Medical Center;   American Urological Association
Recruiting

Fri, 19 Mar 2021 12:00:00 EDT

Testosterone for Men With Insulin Treated Type 2 Diabetes

Conditions:   Hypogonadism;   Diabetes
Interventions:   Drug: Testosterone;   Drug: 0.9% saline
Sponsor:   Barnsley Hospital
Completed

Fri, 07 Jul 2006 12:00:00 EDT

Regulation of Cortisol Metabolism and Fat Patterning

Conditions:   Obesity;   Menopausal Syndrome
Interventions:   Drug: Placebo injection;   Drug: Depo Lupron/Aromatase inhibitor;   Drug: Depo Lupron/placebo;   Drug: placebo;   Drug: Estrogen cream
Sponsors:   Oregon Health and Science University;   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Unknown status

Tue, 10 Jun 2008 12:00:00 EDT

A Study to Characterize Epidemiology, Clinical and Genetic Features of Kallmann Syndrome in Finland

Condition:   Kallmann Syndrome
Intervention:   Drug: Short withdrawal of testosterone, gonadotropins or estrogenic compounds (see below)
Sponsor:   Hospital for Children and Adolescents, Finland
Enrolling by invitation

Mon, 25 Feb 2008 12:00:00 EST

Testosterone for Peripheral Vascular Disease

Conditions:   Hypogonadism;   Peripheral Vascular Disease;   Type 2 Diabetes
Interventions:   Drug: Testosterone;   Drug: saline
Sponsor:   Barnsley Hospital
Completed

Fri, 20 Jul 2007 12:00:00 EDT

Assessment of Drug-drug Interactions Between Masculinizing Hormone Therapy and Antiretroviral Agents Concomitantly for Pre-exposure Prophylaxis Among Transgender Men

Condition:   Drug Interaction
Intervention:   Drug: Emtricitabine 200 mg/tenofovir disoproxil fumarate 300 mg (F/TDF) and emtricitabine 200 mg/tenofovir alafenamide 25 mg (F/TAF)
Sponsor:   Thai Red Cross AIDS Research Centre
Recruiting

Tue, 20 Oct 2020 12:00:00 EDT

Testosterone Replacement in Diabetes With Vascular Disease (Version 2)

Conditions:   Diabetes Mellitus;   Peripheral Vascular Disease
Interventions:   Drug: Testosterone;   Drug: 0.9% saline
Sponsor:   Barnsley Hospital
Completed

Mon, 24 Jul 2006 12:00:00 EDT

Testosterone Administration and ACL Reconstruction in Men

Conditions:   Muscle Atrophy;   ACL Reconstruction;   Trauma;   Osteoarthritis
Interventions:   Drug: Testosterone;   Drug: Saline
Sponsors:   University of Southern California;   Boston University;   University of Oregon
Unknown status

Thu, 10 May 2012 12:00:00 EDT

Multimodal Therapeutic Approach in Undernourished Maintenance Hemodialysis Patients (AMERICANO)

Condition:   Chronic Kidney Failure
Interventions:   Other: training on ergonomic bicycle;   Drug: Testosterone;   Drug: Oral nutritional supplementation;   Drug: n3 polyunsaturated fatty acid
Sponsors:   University Hospital, Clermont-Ferrand;   Human Nutrition Research Center Rhône-Alpes;   Société Francophone Nutrition Clinique et Métabolisme;   Nutricia, Inc.
Unknown status

Thu, 16 Apr 2015 12:00:00 EDT

Effects of Sex Steroid Hormones on Human Brain Function, Structure and Connectivity

Condition:   Gender Identity Disorder
Intervention:   Drug: Hormones
Sponsor:   Medical University of Vienna
Completed

Thu, 10 Feb 2011 12:00:00 EST

A Study to Assess the Efficacy, Safety and Tolerability of Oral LPCN 1144 in Subjects With Nonalcoholic Steatohepatitis (NASH)

Condition:   Nonalcoholic Steatohepatitis (NASH)
Interventions:   Drug: LPCN 1144 Formulation A;   Drug: LPCN 1144 Formulation B;   Drug: Placebo
Sponsor:   Lipocine Inc.
Active, not recruiting

Mon, 21 Oct 2019 12:00:00 EDT

Rapid Hormonal Cycling as Treatment for Patients With Prostate Cancer: The Men's Cycle

Conditions:   Prostate;   Cancer;   Hormonal Cycling
Interventions:   Drug: GnRH;   Drug: Ketoconazole;   Drug: Bicalutamide;   Drug: Testosterone transdermal gel;   Drug: Estrogen transdermal patch
Sponsor:   Memorial Sloan Kettering Cancer Center
Completed

Mon, 07 Jan 2008 12:00:00 EST

The Effect of Ibuprofen on Women With PCOS.

Conditions:   PCOS;   Hyperandrogenism;   Inflammation
Intervention:   Drug: Ibuprofen
Sponsor:   Poznan University of Medical Sciences
Enrolling by invitation

Fri, 24 Jul 2020 12:00:00 EDT

Salivary Testosterone in Men: Diurnal Variation and Post-Prandial Responses

Condition:   Hypogonadism, Male
Interventions:   Other: Testosterone Measurements in healthy volunteers after fasting;   Other: Testosterone Measurements after glucose loading
Sponsor:   The Royal Wolverhampton Hospitals NHS Trust
Recruiting

Mon, 30 Mar 2020 12:00:00 EDT

Clinical Trial to Assess the Effect of Testosterone in Patients With Poor Ovarian Response (TESTOPRIM)

Condition:   Infertility, Female
Interventions:   Drug: GROUP 1: Long testosterone;   Drug: GROUP 2: Short testosterone;   Drug: GROUP 3: Control
Sponsor:   Instituto de Investigacion Sanitaria La Fe
Completed

Wed, 20 Dec 2017 12:00:00 EST

Testosterone and Long Pulse Stimulation After SCI

Condition:   Spinal Cord Injury
Interventions:   Device: Testosterone and LPWS;   Drug: Testosterone and standard NMES
Sponsors:   VA Office of Research and Development;   Hunter Holmes McGuire VA Medical Center
Recruiting

Fri, 17 Nov 2017 12:00:00 EST

Testosterone Replacement in Postmenopausal Women With Stress Urinary Incontinence

Condition:   Stress Urinary Incontinence
Interventions:   Drug: Testosterone patch;   Drug: Placebo
Sponsor:   Charles Drew University of Medicine and Science
Completed

Fri, 14 Apr 2017 12:00:00 EDT

Pharmacokinetics, Pharmacodinamic and Safety of Testosterone Gel 1%

Condition:   Post-menopausal Period
Interventions:   Drug: Testosterone gel 1% 2.2 mg;   Drug: Testosterone gel 1% 4.4 mg;   Drug: Testosterone gel 1% 8.8 mg;   Drug: Placebo of Testosterone Gel 1%
Sponsor:   Biolab Sanus Farmaceutica
Withdrawn

Fri, 29 Jan 2016 12:00:00 EST

Transdermal Testosterone Nanoemulsion in Women Libido

Condition:   Menopause
Interventions:   Drug: Testosterone;   Drug: Placebo
Sponsors:   University Potiguar;   Farmacias Evidence Ltda;   Lemos laboratório de Análises Clínicas
Unknown status

Fri, 15 May 2015 12:00:00 EDT

Safety Study of Transdermal Testosterone for Low Libido in Pre and Postmenopausal Women

Condition:   Sex Behavior
Interventions:   Drug: Biolipid B2 (blanked/placebo);   Drug: Testosterone, Transdermal, Behavior
Sponsors:   University Potiguar;   Universidade Federal do Ceara;   Federal Institute of Science and Technology of Ceara
Completed

Wed, 13 Aug 2014 12:00:00 EDT

Testosterone Antidepressant Augmentation in Women

Condition:   Depression
Interventions:   Drug: Testosterone;   Drug: Placebo
Sponsors:   Massachusetts General Hospital;   National Institutes of Health (NIH);   Lawley Pharmaceuticals
Completed

Tue, 05 Feb 2013 12:00:00 EST

Resistance Training and Testosterone After Spinal Cord Injury

Condition:   Spinal Cord Injury
Interventions:   Device: Resistance Training and Testosterone Patches;   Drug: Testosterone Patches
Sponsors:   VA Office of Research and Development;   Virginia Commonwealth University
Completed

Fri, 27 Jul 2012 12:00:00 EDT

Safety and Efficacy of Intranasal TBS-1 Treatment of Male Hypogonadism

Condition:   Male Hypogonadism
Intervention:   Drug: Testosterone
Sponsor:   Acerus Pharmaceuticals Corporation
Completed

Tue, 04 Oct 2011 12:00:00 EDT

PK Study of Testosterone Nasal Gel (TBS-2) in Healthy Premenopausal Women

Condition:   Female Sexual Dysfunction
Interventions:   Drug: Low dose testosterone nasal gel, single dose;   Drug: Medium dose testosterone nasal gel, single dose;   Drug: High dose testosterone nasal gel, single dose;   Drug: Medium dose testosterone nasal gel, multiple dose
Sponsor:   Acerus Pharmaceuticals Corporation
Completed

Thu, 02 Jun 2011 12:00:00 EDT

Efficacy of Luteinizing Hormone (LH) Activity in Low Responder Patients With Transdermal Testosterone

Condition:   Other Complications Associated With Artificial Fertilization
Interventions:   Drug: Testosterone and FSHr-LHr;   Drug: testosterone and FSHr alone
Sponsor:   Hospital Clinic of Barcelona
Unknown status

Tue, 08 Feb 2011 12:00:00 EST

Efficacy of an Intranasal Testosterone Product

Condition:   Hypogonadism
Interventions:   Drug: 10.0 mg of Testosterone, 4.0% TID;   Drug: 13.5 mg of Testosterone, 4.5% B.I.D;   Drug: 11.25 mg of Testosterone, 4.5% T.I.D
Sponsor:   Acerus Pharmaceuticals Corporation
Completed

Fri, 03 Dec 2010 12:00:00 EST


A Study to Evaluate the Effect of Testosterone on Muscle Fractional Synthetic Rate (MK-0000-064)

Condition:   Muscle Anabolism
Interventions:   Drug: Comparator: Testosterone 300 mg, intramuscular injection;   Drug: Comparator: Testosterone 100 mg, Intramuscular injection;   Drug: Comparator: Placebo given by Intramuscular Injection
Sponsor:   Merck Sharp & Dohme Corp.
Completed

Mon, 05 Jan 2009 12:00:00 EST

Biomarkers of Muscle Anabolism (MK-0000-082)

Condition:   Muscle Anabolism
Interventions:   Drug: Comparator: low dose testosterone;   Drug: Comparator: high dose testosterone;   Drug: Comparator: placebo
Sponsor:   Merck Sharp & Dohme Corp.
Completed

Mon, 22 Dec 2008 12:00:00 EST

Bioequivalence of Testosterone Reduced-size Patch Relative to the Testosterone Reference Patch

Condition:   Healthy
Intervention:   Drug: testosterone
Sponsor:   Warner Chilcott
Completed

Mon, 17 Nov 2008 12:00:00 EST

Hormone and Information Processing Study

Conditions:   Mild Cognitive Impairment;   Alzheimer's Disease
Interventions:   Drug: testosterone gel;   Drug: placebo gel
Sponsors:   University of Washington;   National Institute on Aging (NIA);   Solvay Pharmaceuticals
Completed

Thu, 04 Oct 2007 12:00:00 EDT

Hormone Treatment in Growth Hormone and Testosterone Deficient Patients

Condition:   Hormone Deficiency
Interventions:   Drug: Genotropin;   Drug: Testosterone undecannoate
Sponsors:   Max-Planck-Institute of Psychiatry;   Schoen Clinic Bad Aibling
Terminated

Tue, 19 Jul 2011 12:00:00 EDT

Hypofractionated Radiation Therapy in Treating Participants With Prostate Cancer High-Risk Features Following Radical Prostatectomy

Conditions:   Prostate Adenocarcinoma;   Stage IIB Prostate Cancer AJCC v8;   Stage III Prostate Cancer AJCC v8;   Stage IIIA Prostate Cancer AJCC v8;   Stage IIIB Prostate Cancer AJCC v8;   Stage IIIC Prostate Cancer AJCC v8
Interventions:   Drug: Androgen Suppression;   Radiation: Hypofractionated Radiation Therapy;   Other: Quality-of-Life Assessment;   Other: Questionnaire Administration
Sponsors:   Mayo Clinic;   National Cancer Institute (NCI)
Active, not recruiting

Wed, 27 Jun 2018 12:00:00 EDT

Effects and Safety of OPK-88004 Doses in Men With Signs and Symptoms of Benign Prostatic Hyperplasia (BPH)

Condition:   Benign Prostatic Hyperplasia
Interventions:   Drug: Group-1 (15mg, OPK-88004);   Drug: Group-2 (25 mg,OPK-88004);   Other: Placebo
Sponsor:   OPKO Health, Inc.
Terminated

Fri, 29 Sep 2017 12:00:00 EDT

Clinical Trials of Adjuvant Androgen Deprivation in Localized Prostate Cancer

Condition:   Prostate Adenocarcinoma
Interventions:   Drug: Short term androgen deprivation;   Drug: Long term androgen deprivation;   Radiation: Short term androgen deprivation;   Radiation: Long term androgen deprivation
Sponsor:   Fundación de Investigación Biomédica - Hospital Universitario de La Princesa
Completed

Thu, 26 Jun 2014 12:00:00 EDT

Efficacy Study Evaluating Chemotherapy in Prostate Cancer

Condition:   Prostate Cancer
Interventions:   Drug: Cabazitaxel + Androgen deprivation therapy;   Drug: Androgen deprivation therapy
Sponsor:   Örebro University, Sweden
Unknown status

Fri, 08 Nov 2013 12:00:00 EST

ITT4 Intratesticular Hormonal Milieu in Man (ITT4)

Condition:   Healthy Males
Interventions:   Drug: Acyline;   Drug: Testosterone gel;   Drug: ketoconazole 400;   Drug: Ketoconazole 800;   Drug: Dutasteride;   Drug: Anastrozole;   Drug: Placebo ketoconazole
Sponsors:   University of Washington;   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Completed

Wed, 06 Oct 2010 12:00:00 EDT

HOP-3 Manipulation of the Intratesticular Hormonal Milieu With Exogenous Testosterone

Condition:   Healthy Males
Interventions:   Drug: Acyline;   Other: placebo hCG (no active ingredient);   Drug: hCG (human chorionic gonadotropin);   Drug: Testosterone gel
Sponsors:   University of Washington;   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Completed

Mon, 09 Feb 2009 12:00:00 EST

Insulin Sensitivity in Men With the Metabolic Syndrome

Condition:   Metabolic Syndrome
Interventions:   Procedure: intravenous glucose tolerance test;   Drug: testosterone;   Drug: anastrozole;   Drug: goserelin acetate implant;   Procedure: aerobic capacity (VO2 Max);   Procedure: MRI;   Procedure: muscle biopsy;   Procedure: measurement of resting metabolic rate (energy expenditure);   Procedure: Dual energy x-ray absorptiometry;   Procedure: Fasting oral glucose tolerance test
Sponsors:   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK);   American Diabetes Association
Suspended

Fri, 09 Feb 2007 12:00:00 EST

Product Transference Study of Testagen™ TDS®-Testosterone

Condition:   Hypogonadotropism
Intervention:   Drug: Testagen® TDS Testosterone 5% HypoSpray®
Sponsors:   Transdermal Delivery Solutions Corp;   Advanced Therapies Centre, The London Clinic
Enrolling by invitation

Mon, 11 Apr 2016 12:00:00 EDT

Pharmacokinetics of a Novel Vaginal Delivery System for Testosterone and Dehydroepiandrosterone (DHEA)

Conditions:   Pharmacokinetics;   Hormone Deficiency
Interventions:   Drug: Dehydroepiandrosterone 2.2 g;   Drug: Dehydroepiandrosterone 1.5 g/Testosterone 25 mg;   Drug: Testosterone;   Drug: Testosterone Topical Gel;   Drug: Dehydroepiandrosterone Oral Capsule
Sponsor:   Laboratorios Andromaco S.A.
Completed

Thu, 30 May 2019 12:00:00 EDT

Testosterone Implants and the Incidence of Breast Cancer

Condition:   Breast Cancer
Intervention:   Drug: Testosterone Implant
Sponsor:   Millennium Wellness LLC
Completed

Fri, 07 Dec 2018 12:00:00 EST

A Single Dose Trial to Evaluate the Pharmacokinetics of Testosterone and Anastrozole

Condition:   Mammographic Density
Intervention:   Drug: testosterone anastrozole
Sponsor:   Havah Therapeutics Pty Ltd
Completed

Thu, 19 Oct 2017 12:00:00 EDT

Metabolic Effects of Steroids in Obese Men

Conditions:   Obesity;   Insulin Resistance
Interventions:   Drug: Anastrazole;   Drug: Testosterone;   Drug: Dutasteride;   Drug: GnRH antagonist
Sponsors:   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK);   University of California, San Diego
Unknown status

Thu, 24 Sep 2009 12:00:00 EDT

Effects of Interleukin-1 Receptor Antagonism on Hyperandrogenemia in Women With Polycystic Ovary Syndrome

Condition:   Polycystic Ovary Syndrome
Intervention:   Drug: IL-1 receptor antagonist Anakinra
Sponsor:   University Hospital, Basel, Switzerland
Completed

Fri, 06 Jul 2018 12:00:00 EDT

Effect of Testosterone Treatment on Embryo Quality

Conditions:   Primary Ovarian Insufficiency;   Female Infertility Due to Diminished Ovarian Reserve
Interventions:   Drug: Testosterone cream (0.5mg per gram);   Dietary Supplement: DHEA;   Drug: Placebo
Sponsors:   Center for Human Reproduction;   Foundation for Reproductive Medicine
Recruiting

Fri, 10 Aug 2012 12:00:00 EDT

Study On Bioavailability And Pharmacokinetics Of Various Doses Of Testosterone Administered With And Without Dutasteride

Conditions:   Hypogonadism;   Hypogonadism, Male
Interventions:   Drug: Nanomilled testosterone;   Drug: commercially available dutasteride;   Drug: Nanomilled dutasteride
Sponsor:   GlaxoSmithKline
Completed

Thu, 16 Nov 2006 12:00:00 EST

28-Day Study of Testosterone Co-administered With Dutasteride in Hypogonadal Men

Conditions:   Hypogonadism;   Hypogonadism, Male
Interventions:   Drug: Nanomilled testosterone;   Drug: Nanomilled dutasteride;   Drug: commercially available dutasteride
Sponsor:   GlaxoSmithKline
Completed

Fri, 10 Nov 2006 12:00:00 EST

Sex Hormones & Serum Sclerostin Level

Conditions:   Bony Sclerosis;   Testicular; Hormone, C
Intervention:  
Sponsor:   Bagcilar Training and Research Hospital
Completed

Wed, 17 Aug 2011 12:00:00 EDT

Oral Testosterone for the Treatment of Hypogonadism in Males

Condition:   Hypogonadism
Intervention:   Drug: TSX-002
Sponsor:   TesoRx Pharma, LLC
Completed

Thu, 21 Aug 2014 12:00:00 EDT

Oral Testosterone for the Treatment of Hypogonadism

Condition:   Hypogonadism
Intervention:   Drug: TSX-002
Sponsor:   TesoRx Pharma, LLC
Completed

Tue, 30 Oct 2012 12:00:00 EDT

Real-life Evaluation of the Effect of ADT in Prostate Cancer Patients in Asia (READT Asia Study)

Condition:   Prostate Cancer
Interventions:   Procedure: Androgen deprivation therapy - bilateral orchidectomy;   Drug: Androgen deprivation therapy - GnRH agonist;   Drug: Androgen deprivation therapy - GnRH antagonist
Sponsor:   Chinese University of Hong Kong
Recruiting

Fri, 12 Oct 2018 12:00:00 EDT

Effect of Testosterone Treatment on Clitoral Arteries' Hemodynamic Parameters.

Conditions:   Hypoactive Sexual Desire Disorder;   Vulvovaginal Disease;   Menopause Related Conditions;   Dyspareunia (Female Excluding Psychogenic);   Hypoestrogenism;   Arousal Disorders, Sexual
Interventions:   Drug: Testosterone gel;   Drug: Estradiol ovules;   Drug: Moisturizer;   Drug: Testosterone gel + Estradiol ovules
Sponsor:   University of Florence
Completed

Tue, 07 Apr 2020 12:00:00 EDT

Cardiovascular Outcomes of Low Testosterone

Condition:   Hypogonadism
Interventions:   Drug: Acyline;   Drug: Placebo Gel;   Drug: Placebo Tablet;   Drug: Testosterone Gel;   Drug: Arimidex
Sponsor:   University of Colorado, Denver
Recruiting

Mon, 02 May 2016 12:00:00 EDT

Steroid Profile: Differentiating Testosterone Administration From (Simultaneous) Ethanol Consumption

Condition:   Healthy Volunteers
Interventions:   Drug: Testosterone gel;   Drug: Ethanol Solution;   Drug: Testosterone placebo (vaseline);   Drug: Ethanol placebo (lemon-flavoured water)
Sponsor:   Parc de Salut Mar
Completed

Mon, 18 Nov 2019 12:00:00 EST

Hormone Suppression and Radiation Therapy for 6 Months With/Without Docetaxel for High Risk Prostate Cancer

Condition:   Prostate Cancer
Interventions:   Drug: Docetaxel;   Drug: Androgen Hormonal Suppression and Radiation;   Drug: Androgen Suppression Therapy and Radiation Therapy
Sponsors:   Dana-Farber Cancer Institute;   Sanofi
Completed

Tue, 28 Jun 2005 12:00:00 EDT

CEP-1 Hormonal Regulation of Circulating Endothelial Progenitor Cells and HDL-C in Men

Condition:   Healthy
Interventions:   Drug: Acyline;   Drug: Acyline + Testosterone gel;   Drug: Acyline + testosterone gel + anastrozole
Sponsors:   University of Washington;   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Completed

Fri, 08 Aug 2008 12:00:00 EDT

ORAL T-6: Oral Androgens in Man-6

Conditions:   Contraception;   Hypogonadism
Interventions:   Drug: Acyline;   Drug: Testosterone;   Drug: Finasteride
Sponsors:   University of Washington;   National Institutes of Health (NIH);   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Completed

Tue, 22 Apr 2008 12:00:00 EDT

Safety and Efficacy Study of a Testosterone Eye Drop for the Treatment of Meibomian Gland Dysfunction

Condition:   Meibomian Gland Dysfunction
Interventions:   Drug: testosterone ophthalmic solution;   Drug: vehicle of testosterone ophthalmic solution
Sponsor:   ORA, Inc.
Completed

Thu, 18 Sep 2008 12:00:00 EDT

Vaginal Testosterone Cream vs ESTRING for Vaginal Dryness or Decreased Libido in Early Stage Breast Cancer Patients

Condition:   Sexual Dysfunction, Physiological
Interventions:   Drug: Testosterone Cream;   Drug: Estring
Sponsor:   University of California, San Francisco
Completed

Mon, 16 Jun 2008 12:00:00 EDT

Assessment of the Treatment of Severely Burned With Anabolic Agents on Clinical Outcomes, Recovery and Rehabilitation

Condition:   Burns
Interventions:   Procedure: Stable Isotope Infusion Study;   Procedure: Collection of blood and tissues;   Procedure: Radiology testing: Dual-energy X-ray absorptiometry (DEXA), ultrasound, MRI;   Drug: Humatrope;   Drug: Ketoconazole;   Drug: Oxandrolone;   Drug: Propranolol;   Drug: Oxandrolone and propranolol combined;   Drug: Humatrope and propranolol combined;   Drug: Placebo;   Behavioral: Exercise--Hospital supervised intensive exercise program;   Behavioral: Home exercise program
Sponsors:   The University of Texas Medical Branch, Galveston;   U.S. Department of Education;   National Institutes of Health (NIH);   National Institute of General Medical Sciences (NIGMS)
Terminated

Mon, 12 May 2008 12:00:00 EDT

Stereotactic Body Radiation Therapy in Treating Patients With Localized Prostate Cancer That Have Undergone Surgery

Conditions:   PSA Level Greater Than 0.03;   PSA Progression;   Stage I Prostate Adenocarcinoma AJCC (American Joint Committee on Cancer ) v7;   Stage II Prostate Adenocarcinoma AJCC v7;   Stage III Prostate Adenocarcinoma AJCC v7
Interventions:   Drug: Antiandrogen Therapy;   Other: Quality-of-Life Assessment;   Radiation: Stereotactic Body Radiation Therapy
Sponsors:   Jonsson Comprehensive Cancer Center;   Viewray Inc.
Recruiting

Thu, 31 May 2018 12:00:00 EDT

PLX3397, Radiation Therapy, and Antihormone Therapy in Treating Patients With Intermediate- or High-Risk Prostate Cancer

Conditions:   Stage I Prostate Adenocarcinoma;   Stage II Prostate Adenocarcinoma;   Stage III Prostate Adenocarcinoma
Interventions:   Drug: Antiandrogen Therapy;   Other: Laboratory Biomarker Analysis;   Drug: Multitargeted Tyrosine Kinase Inhibitor PLX3397;   Radiation: Radiation Therapy
Sponsors:   Barbara Ann Karmanos Cancer Institute;   National Cancer Institute (NCI)
Completed

Mon, 15 Jun 2015 12:00:00 EDT

Therapeutic Effect of Cytoreductive Radical Prostatectomy in Men With Newly Diagnosed Metastatic Prostate Cancer

Condition:   Stage IV Prostate Adenocarcinoma AJCC v7
Interventions:   Drug: Antiandrogen Therapy;   Drug: Docetaxel;   Other: Laboratory Biomarker Analysis;   Procedure: Quality-of-Life Assessment;   Other: Questionnaire Administration;   Procedure: Radical Prostatectomy
Sponsors:   Rutgers, The State University of New Jersey;   National Cancer Institute (NCI)
Recruiting

Wed, 07 Mar 2018 12:00:00 EST

Androgen Ablation Therapy With or Without Niraparib After Radiation Therapy for the Treatment of High-Risk Localized or Locally Advanced Prostate Cancer

Conditions:   Prostate Carcinoma;   Stage IIC Prostate Cancer AJCC v8;   Stage III Prostate Cancer AJCC v8;   Stage IIIA Prostate Cancer AJCC v8;   Stage IIIB Prostate Cancer AJCC v8;   Stage IIIC Prostate Cancer AJCC v8;   Stage IVA Prostate Cancer AJCC v8
Interventions:   Drug: Abiraterone Acetate;   Drug: Antiandrogen Therapy;   Drug: Apalutamide;   Procedure: Biopsy;   Drug: Niraparib;   Drug: Prednisone;   Radiation: Radiation Therapy
Sponsor:   M.D. Anderson Cancer Center
Recruiting

Thu, 01 Jul 2021 12:00:00 EDT

Study of Lanreotide in Non Metastatic Castration-resistant Prostate Cancer Patients

Condition:   Prostate Cancer
Interventions:   Drug: Lanreotide, non steroidal anti androgens and LHRH-a;   Drug: Non steroidal anti androgens and LHRH-a
Sponsor:   Ipsen
Terminated

Fri, 11 Mar 2011 12:00:00 EST

Advanced ChemoHormonal Therapy for Treatment Naive Metastatic Prostate Cancer

Conditions:   Castration-Sensitive Prostate Carcinoma;   Metastatic Prostate Carcinoma;   Stage IV Prostate Cancer AJCC v8;   Stage IVA Prostate Cancer AJCC v8;   Stage IVB Prostate Cancer AJCC v8
Interventions:   Drug: Abiraterone Acetate;   Drug: Antiandrogen Therapy;   Drug: Apalutamide;   Drug: Prednisone;   Other: Quality-of-Life Assessment;   Other: Questionnaire Administration
Sponsors:   OHSU Knight Cancer Institute;   Janssen Scientific Affairs, LLC;   Oregon Health and Science University
Recruiting

Thu, 13 Feb 2020 12:00:00 EST

Antiandrogen Therapy, Abiraterone Acetate, and Prednisone With or Without Neutron Radiation Therapy in Treating Patients With Prostate Cancer

Conditions:   Castration-Sensitive Prostate Carcinoma;   Metastatic Malignant Neoplasm in the Bone;   Metastatic Prostate Carcinoma;   Prostate Adenocarcinoma;   Prostate Small Cell Neuroendocrine Carcinoma;   Stage IV Prostate Cancer AJCC v8;   Stage IVA Prostate Cancer AJCC v8;   Stage IVB Prostate Cancer AJCC v8
Interventions:   Drug: Antiandrogen Therapy;   Drug: Abiraterone Acetate;   Drug: Prednisone;   Radiation: Radiation Therapy
Sponsors:   University of Washington;   National Cancer Institute (NCI)
Recruiting

Tue, 28 Aug 2018 12:00:00 EDT

Abiraterone Acetate and Antiandrogen Therapy With or Without Cabazitaxel and Prednisone in Treating Patients With Metastatic, Castration-Resistant Prostate Cancer Previously Treated With Docetaxel

Conditions:   Castration Levels of Testosterone;   Castration-Resistant Prostate Carcinoma;   Metastatic Prostate Carcinoma in the Soft Tissue;   Prostate Carcinoma Metastatic in the Bone;   Stage IV Prostate Adenocarcinoma AJCC v7
Interventions:   Drug: Abiraterone Acetate;   Drug: Antiandrogen Therapy;   Drug: Cabazitaxel;   Other: Laboratory Biomarker Analysis;   Procedure: Orchiectomy;   Other: Pharmacological Study;   Drug: Prednisone
Sponsors:   ECOG-ACRIN Cancer Research Group;   National Cancer Institute (NCI)
Recruiting

Thu, 01 Feb 2018 12:00:00 EST

Pembrolizumab +/- SD-101 in Hormone-Naïve Oligometastatic Prostate Cancer With RT and iADT

Condition:   Prostatic Neoplasms
Interventions:   Drug: Pembrolizumab;   Drug: SD-101;   Drug: Leuprolide acetate;   Drug: Abiraterone Acetate;   Drug: Prednisone;   Radiation: Stereotactic Body Radiation Therapy
Sponsors:   Lawrence Fong;   Prostate Cancer Foundation;   Merck Sharp & Dohme Corp.;   Dynavax Technologies Corporation
Recruiting

Mon, 02 Jan 2017 12:00:00 EST

External Beam Radiation With or Without Chemotherapy to Treat High Risk Prostate Cancer

Condition:   Prostate Cancer
Interventions:   Drug: Luteinizing hormone-releasing hormone (LHRH);   Drug: Docetaxel;   Other: Conformal Radiation Therapy (RT)
Sponsor:   Proton Collaborative Group
Terminated

Tue, 22 May 2012 12:00:00 EDT

Antiandrogen Therapy With or Without Axitinib Before Surgery in Treating Patients With Previously Untreated Prostate Cancer With Known or Suspected Lymph Node Metastasis

Conditions:   Metastatic Malignant Neoplasm in Lymph Node;   Prostate Ductal Adenocarcinoma;   Stage III Prostate Adenocarcinoma AJCC v7;   Stage IV Prostate Adenocarcinoma AJCC v7
Interventions:   Drug: Antiandrogen Therapy;   Drug: Axitinib;   Procedure: Radical Prostatectomy;   Procedure: Regional Lymph Node Dissection
Sponsors:   M.D. Anderson Cancer Center;   National Cancer Institute (NCI)
Active, not recruiting

Thu, 04 Aug 2011 12:00:00 EDT

Docetaxel or Abiraterone Acetate With ADT in Treating Patients With Metastatic Hormone Sensitive Prostate Cancer

Conditions:   Castration-Sensitive Prostate Carcinoma;   Metastatic Prostatic Adenocarcinoma;   Stage IV Prostate Cancer;   Stage IVA Prostate Cancer;   Stage IVB Prostate Cancer
Interventions:   Drug: Abiraterone Acetate;   Drug: Antiandrogen Therapy;   Drug: Docetaxel;   Drug: Prednisone;   Other: Quality-of-Life Assessment;   Other: Questionnaire Administration
Sponsor:   University of Utah
Terminated

Fri, 01 Feb 2019 12:00:00 EST

Samarium-153 With Neoadjuvant Hormonal and Radiation Therapy for Locally Advanced Prostate Cancer

Condition:   Prostate Cancer
Interventions:   Drug: Samarium-153;   Drug: Total Androgen Suppression (TAS) with Bicalutamide;   Drug: Total androgen suppression (TAS) with Goserelin Acetate;   Device: Radiation Therapy
Sponsors:   Sidney Kimmel Cancer Center at Thomas Jefferson University;   Cytogen Corporation
Completed

Mon, 22 May 2006 12:00:00 EDT

Androgen Suppression Combined With Elective Nodal and Dose Escalated Radiation Therapy

Condition:   Prostate Cancer
Interventions:   Procedure: Androgen suppression, radiotherapy;   Procedure: Androgen suppression, radiotherapy, iodine 125 brachytherapy
Sponsor:   University of British Columbia
Unknown status

Thu, 15 Sep 2005 12:00:00 EDT