Tramadol Aleve Blend: What You Need To Know


Tramadol and Alev (naproxen) in combination can be used to treat acute pain that is severe enough to require opioid pain relievers . Tramadol is often prescribed when other pain relievers are ineffective or poorly tolerated.

When used together, tramadol and naproxen can provide better pain relief than either drug alone. Occasionally, healthcare providers prescribe two medications in lower doses to provide better relief without taking too much of either of them. Find out more about Tramadol and Aleva and if it is safe to take them together.

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What is Tramadol?

Tramadol is an oral medication that can relieve ongoing moderate to severe pain. It works in the same way as other opioid pain relievers . It works in the brain to change the way the body feels and responds to pain. Tramadol is available as a generic drug with several brand names: Ultram, Ultram ER, Ryzolt, and ConZip.

Tramadol is a controlled substance, drug, or other substance that is strictly controlled by the government because it can cause abuse or addiction . It is only available as a prescription treatment where your healthcare provider will need to monitor your use of the drug.

Tramadol comes in many different forms. what includes:

  • Capsules: immediate and prolonged release.
  • Tablets: immediate and prolonged release.
  • Chewable tablets
  • Suppositories
  • Effervescent tablets and powders
  • Sterile solutions for intravenous administration (through a vein)
  • Solutions that can be injected into the column
  • Oral fluids
  • Tablets combined with paracetamol , aspirin or other pain relievers.

The side effects of tramadol are mild and will lessen after you take the drug for a while.

Mild side effects of tramadol can include:

  • Nausea or vomiting
  • Constipation
  • Lightheadedness or dizziness
  • Headache
  • Drowsiness
  • Itching

The more serious side effects of tramadol can include:

  • Interrupted breathing during sleep ( sleep apnea )
  • Mental or mood changes
  • Severe abdominal pain
  • Difficulty urinating
  • Adrenal Dysfunction – Signs include loss of appetite, unusual tiredness, weight loss, etc.

Be sure to seek medical attention in case of serious side effects.

Major side effects, including fast or irregular heartbeat, severe dizziness, fainting, or seizures , can be signs of a medical emergency and you should seek medical attention immediately.

An allergic reaction to tramadol is rare. Call your doctor if you have signs of an allergic reaction including a rash, itching, swelling of the face, throat, or tongue, severe dizziness, or trouble breathing.

Opioid warnings

The risk of dependence on opioids is high. Fortunately, tramadol has a lower risk of addiction. However, it can still be abused and is associated with the risk of overdose and death.

A survey sponsored by the Drug Enforcement and Mental Health Services Administration (SAMHSA) found that 8.1% of tramadol users were abused.

People who abuse tramadol are at risk of overdose and possibly death. Deaths from synthetic opioid overdoses, including tramadol, increased 45% between 2016 and 2017, according to the Centers for Disease Control and Prevention.

Always take Tramadol exactly as your healthcare provider has prescribed. Do not take more than prescribed or pass this medicine to others.

What is Aleve?

Aleve is a brand name for naproxen . Naproxen belongs to a class of drugs called non- steroidal anti-inflammatory drugs (NSAIDs), drugs that are commonly used to relieve mild to moderate pain, inflammation , and fever.

NSAIDs block cyclooxygenase , enzymes that promote the development of prostaglandins . Prostaglandins cause inflammation, pain, and fever. Taking NSAIDs like naproxen can reduce these symptoms.

Alev is used to treat pain in a variety of conditions, including headaches, muscle aches, toothaches, and menstrual cramps. It can also control joint pain, swelling, stiffness, and inflammation associated with arthritis conditions such as osteoarthritis (OA) and rheumatoid arthritis (RA).

The usual dose for adults is 220 milligrams (mg) to 1000 mg every eight to 12 hours. The recommended dose for RA, OA, or ankylosing spondylitis (AS) is 500 mg to 100 mg every 12 hours. Naproxen should be taken with meals to ease an upset stomach.

NSAID warnings

NSAIDs carry the risk of side effects, and the elderly and people with chronic conditions may be at higher risk. NSAIDs are tolerated by most people. Side effects experienced are usually mild and can be reversed by reducing the dose or taking another medication to counteract them (eg, proton pump inhibitors to treat gastrointestinal [GI] side effects).

Some serious side effects of NSAIDs include:

  • Stomach problems : These can include stomach irritation, abdominal pain, heartburn, gas, diarrhea, constipation, nausea, vomiting, gastrointestinal bleeding , and ulcers. You can reduce some of these by taking NSAIDs with food, milk, or acid-blocking medications. You should avoid drinking alcohol with NSAIDs to reduce your risk of gastrointestinal bleeding.
  • Heart attack and stroke : Most NSAIDs can increase the risk of stroke and heart attack. NSAIDs have a black box that warns of increased risk . The warning indicates that a risk may arise after a few weeks of use, with prolonged use and more likely with higher doses. The risk is present with or without other risk factors for heart disease or stroke.
  • High blood pressure : All NSAIDs can raise blood pressure in people with and without high blood pressure. This side effect can occur even when taking blood pressure medications.
  • Kidney problems : The most common kidney problem associated with NSAIDs is fluid retention, mainly swollen ankles and feet. According to the National Kidney Foundation, NSAIDs carry an increased risk of sudden kidney failure or damage . The Foundation recommends that people with already impaired kidney function avoid taking NSAIDs.
  • Allergic reactions : Allergic reactions to NSAIDs are rare. Symptoms of an allergic reaction include swollen lips, tongue, or eyes, trouble breathing, wheezing, trouble swallowing, a rash, or hives.
  • Bruising or bleeding : NSAIDs affect the blood's ability to clot. This can cause easy bruising and cuts that take longer to stop the bleeding. People taking blood thinners should talk to their healthcare provider before taking NSAIDs.
  • Other Side Effects : Some people may experience dizziness, poor balance, or trouble concentrating.

Check with your doctor if you experience serious or persistent side effects. If you experience more serious or dangerous side effects (such as signs of a stroke or heart attack), seek emergency help.

Is it safe to take Aleve with Tramadol?

Using tramadol with NSAIDs can exacerbate side effects , which may be more common in older people and people with chronic medical conditions . However, studies have shown that taking tramadol with most NSAIDs is safe for people over the age of 16.

A study published in 2016 aims to determine whether combination therapy with low-dose tramadol and NSAIDs can prevent the progression from acute low back pain to chronic low back pain. It confirmed that the low-dose tramadol / NSAID combination can reduce the likelihood of side effects while preventing acute low back pain from becoming chronic.

Acute back pain is back pain that occurs suddenly, usually as a result of a known injury. It often goes away in a few days, but can last up to six weeks. Chronic back pain is back pain that develops slowly over time or can progress over time. Pain that lasts three or more months is considered chronic.

Always consult your doctor before changing your medication regimen. Discuss whether it is safe to take tramadol / naproxen combination therapy with other medications you are taking, including vitamins and supplements.

Get the word of drug information

Tramadol and Aleve are effective pain relievers for chronic and acute pain. But these drugs carry many risks, including serious side effects, overdose and death, and, as is the case with tramadol, the potential for abuse.

Make sure you take tramadol and naproxen exactly as prescribed by your healthcare provider and for the recommended time.

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