Full text biomedical articles

Trihexyphenidyl for dystonia in cerebral palsy

Adrienne R Harvey, Louise B Baker, Dinah Susan Reddihough, Adam Scheinberg, Katrina Williams, Cochrane Developmental, Psychosocial and Learning Problems Group
Cochrane Database Syst Rev. 2018 May; 2018(5): CD012430. Published online 2018 May 15. doi: 10.1002/14651858.CD012430.pub2

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Trihexyphenidyl rescues the deficit in dopamine neurotransmission in a mouse model of DYT1 dystonia

Anthony M. Downs, Xueliang Fan, Christine Donsante, H.A. Jinnah, Ellen J. Hess
Neurobiol Dis. Author manuscript; available in PMC 2020 May 1.
Published in final edited form as: Neurobiol Dis. 2019 May; 125: 115–122. Published online 2019 Jan 30. doi: 10.1016/j.nbd.2019.01.012

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Trihexyphenidyl induced malignant hyperthermia in a patient with Parkinson's disease complicated with pneumonia: A case report

Jun Zhao, Gang Xu, Congrui Feng, Yuluo Chen, Yanhong Kang, Feng Liu, Wei Ma
Medicine (Baltimore) 2020 May 15; 99(20): e20129. Published online 2020 May 15. doi: 10.1097/MD.0000000000020129

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Long-term trihexyphenidyl exposure alters neuroimmune response and inflammation in aging rat: relevance to age and Alzheimer’s disease

Yuqi Huang, Zhe Zhao, Xiaoli Wei, Yong Zheng, Jianqiang Yu, Jianquan Zheng, Liyun Wang
J Neuroinflammation. 2016; 13: 175. Published online 2016 Jul 1. doi: 10.1186/s12974-016-0640-5

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A Novel Reduced Graphene Oxide Modified Carbon Paste Electrode for Potentiometric Determination of Trihexyphenidyl Hydrochloride in Pharmaceutical and Biological Matrices

Josip Radić, Maša Buljac, Boštjan Genorio, Ema Gričar, Mitja Kolar
Sensors (Basel) 2021 May; 21(9): 2955. Published online 2021 Apr 23. doi: 10.3390/s21092955

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Antagonism by (R)- and (S)-trihexyphenidyl of muscarinic stimulation of adenylyl cyclase in rat olfactory bulb and inhibition in striatum and heart.

P Onali, A J Aasen, M C Olianas
Br J Pharmacol. 1994 Nov; 113(3): 775–780. doi: 10.1111/j.1476-5381.1994.tb17060.x

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Binding and functional profiles of the selective M1 muscarinic receptor antagonists trihexyphenidyl and dicyclomine.

A. Giachetti, E. Giraldo, H. Ladinsky, E. Montagna
Br J Pharmacol. 1986 Sep; 89(1): 83–90. doi: 10.1111/j.1476-5381.1986.tb11123.x

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Impaired absorption of chlorpromazine in rats given trihexyphenidyl.

L Rivera-Calimlim
Br J Pharmacol. 1976 Mar; 56(3): 301–305. doi: 10.1111/j.1476-5381.1976.tb07642.x

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Management of a case of refractory variant angina with benzhexol hydrochloride (trihexyphenidyl hydrochloride).

M Joy, G A Haywood, M M Webb-Peploe
Br Heart J. 1985 Oct; 54(4): 448–451. doi: 10.1136/hrt.54.4.448

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Functional activity of the sensorimotor cortex and cerebellum relates to cervical dystonia symptoms

Roxana G. Burciu, Christopher W. Hess, Stephen A. Coombes, Edward Ofori, Priyank Shukla, Jae Woo Chung, Nikolaus R. McFarland, Aparna Wagle Shukla, Michael S. Okun, David E. Vaillancourt
Hum Brain Mapp. 2017 Sep; 38(9): 4563–4573. Published online 2017 Jun 8. doi: 10.1002/hbm.23684

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Changes in Sensitivity of Reward and Motor Behavior to Dopaminergic, Glutamatergic, and Cholinergic Drugs in a Mouse Model of Fragile X Syndrome

Eric W. Fish, Michael C. Krouse, Sierra J. Stringfield, Jeffrey F. DiBerto, J. Elliott Robinson, C. J. Malanga
PLoS One. 2013; 8(10): e77896. Published online 2013 Oct 18. doi: 10.1371/journal.pone.0077896

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Muscarinic Preferential M1 Receptor Antagonists Minimally Alter the Discriminative-Stimulus Effects of Cocaine in Rats

Gianluigi Tanda, Jonathan L. Katz
Pharmacol Biochem Behav. Author manuscript; available in PMC 2010 Apr 16.
Published in final edited form as: Pharmacol Biochem Behav. 2007 Oct; 87(4): 400–404. Published online 2007 Jun 2. doi: 10.1016/j.pbb.2007.05.015

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Trihexyphenidyl (Artane) Intoxication due to Overdosage with Suicidal Intent

G. F. Morgenstern
Can Med Assoc J. 1962 Jul 14; 87(2): 79–80.

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Effects of muscarinic receptor antagonists on cocaine discrimination in wild-type mice and in muscarinic receptor M1, M2, and M4 receptor knockout mice

Lauren Joseph, Morgane Thomsen
Behav Brain Res. Author manuscript; available in PMC 2018 Jun 30.
Published in final edited form as: Behav Brain Res. 2017 Jun 30; 329: 75–83. Published online 2017 Apr 22. doi: 10.1016/j.bbr.2017.04.023

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An anticholinergic reverses motor control and corticostriatal LTD deficits in Dyt1 ΔGAG knock-in mice

Mai T. Dang, Fumiaki Yokoi, Chad C. Cheetham, Jun Lu, Viet Vo, David M. Lovinger, Yuqing Li
Behav Brain Res. Author manuscript; available in PMC 2013 Jan 15.
Published in final edited form as: Behav Brain Res. 2012 Jan 15; 226(2): 465–472. Published online 2011 Oct 8. doi: 10.1016/j.bbr.2011.10.002

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Cervical Dystonia: From Pathophysiology to Pharmacotherapy

Sejal Patel, Davide Martino
Behav Neurol. 2013; 26(4): 275–282. doi: 10.3233/BEN-2012-120270

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Waddling Gait: A complication of valproate therapy and a thought beyond vitamin D deficiency

Amit Sharma, Siddhartha Sinha, Amit Narang, Dushyant K. Chouhan, Sumit Gupta
Sultan Qaboos Univ Med J. 2020 Feb; 20(1): e104–e108. Published online 2020 Mar 9. doi: 10.18295/squmj.2020.20.01.016

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Transitory procaine-induced Parkinsonism

F. Gjerris
J Neurol Neurosurg Psychiatry. 1971 Feb; 34(1): 20–22. doi: 10.1136/jnnp.34.1.20

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Chewing-induced facial dystonia: a rare presentation of task-specific dystonia

Chandramohan Sharma, Banshi Lal Kumawat, Ankur Garg, Kaushik Kumar Rana
BMJ Case Rep. 2017; 2017: bcr2016218956. Published online 2017 Jul 17. doi: 10.1136/bcr-2016-218956

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Treatment of Dystonia

Mary Ann Thenganatt, Joseph Jankovic
Neurotherapeutics. 2014 Jan; 11(1): 139–152. Published online 2013 Oct 19. doi: 10.1007/s13311-013-0231-4

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